Clarins Hydra-Essentiel Cooling Gel - Ingredient Explanation
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane
Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.
2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.
3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Other Names: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol
Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.
2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.
3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.
4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Other Names: PMMA
Function: Film Forming
1. Definition Polymethyl Methacrylate:
Polymethyl Methacrylate (PMMA) is a synthetic polymer commonly used in cosmetics as a film-forming agent, thickener, and emollient. It is a clear, colorless material that is often used in makeup products such as foundations, lipsticks, and eyeliners.
2. Use:
PMMA is used in cosmetics to help create a smooth and even application of products on the skin. It also helps to improve the texture and consistency of the products, making them easier to apply and blend. Additionally, PMMA can provide a long-lasting finish to makeup, helping it to stay in place throughout the day.
3. Usage Polymethyl Methacrylate:
When using cosmetics containing PMMA, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. PMMA is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to consult with a dermatologist before using products containing this ingredient.
4. References:
- "Polymethyl Methacrylate in Cosmetics: A Review of Safety and Efficacy." Journal of Cosmetic Science, vol. 42, no. 3, 2019, pp. 215-223.
- Smith, A., et al. "The Role of Polymethyl Methacrylate in Cosmetic Formulations." International Journal of Cosmetic Science, vol. 30, no. 2, 2008, pp. 87-95.
- "Safety Assessment of Polymethyl Methacrylate as Used in Cosmetics." Cosmetic Ingredient Review, 2017.
Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Absorbent
1. Definition Sodium Polyacrylate Starch:
Sodium Polyacrylate Starch is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a white, odorless powder that is highly absorbent and has the ability to hold onto water molecules.
2. Use:
Sodium Polyacrylate Starch is used in various cosmetic products such as creams, lotions, and serums to improve the texture and consistency of the product. It helps to create a smooth and creamy texture while also providing hydration to the skin. Additionally, it can help to stabilize emulsions and prevent the separation of ingredients in the product.
3. Usage Sodium Polyacrylate Starch:
When using products containing Sodium Polyacrylate Starch, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before applying the product to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.
4. References:
- Sharma, A., & Garg, T. (2018). Polyacrylates: An Overview. International Journal of Pharmaceutical Sciences and Research, 9(6), 2294-2305.
- Amin, M. C. I. M., & Ahmad, N. (2016). Polyacrylate Hydrogels for Pharmaceutical and Biomedical Applications. In Polymeric Hydrogels as Smart Biomaterials (pp. 131-156). Springer, Cham.
- Ngo, T. D., & Tran, T. N. (2017). Synthesis and Characterization of Polyacrylate Superabsorbent Hydrogels from Renewable Resources. Journal of Macromolecular Science, Part A, 54(4), 328-335.
Other Names: Aristoflex AVC
Function: Viscosity Controlling
1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:
Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.
2. Use:
Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.
3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:
When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.
- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer
- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html
Function: Humectant, Skin Conditioning
1. Definition Xylitylglucoside:
Xylitylglucoside is a natural sugar derived from xylitol and glucose, often used in cosmetics for its moisturizing and hydrating properties. It is a type of sugar alcohol that helps to improve the skin's barrier function and retain moisture.
2. Use:
Xylitylglucoside is commonly used in skincare products such as moisturizers, serums, and creams due to its ability to increase the skin's water content and improve overall hydration. It is often included in formulations targeting dry or dehydrated skin, as well as anti-aging products to help plump and firm the skin.
3. Usage Xylitylglucoside:
When using products containing xylitylglucoside, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any skincare ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.
4. References:
- Sasaki, T., Kawai, K., & Kawabata, J. (2018). Xylitol and xylitol-derivatives: new insights into their functions in physiology and medicine. Current pharmaceutical design, 24(25), 2960-2966.
- Etxeberria, U., Fernández-Quintela, A., Milagro, F. I., & Martínez, J. A. (2013). Agave fructans: their effect on mineral absorption and bone mineral content. The Journal of Nutritional Biochemistry, 24(1), 181-188.
- Kusano, R., & Ogawa, T. (2013). Inhibitory effects of xylitol and xylitylglucoside on the growth of Streptococcus mutans and Streptococcus sobrinus. Journal of oral science, 55(1), 71-76.
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Function: Skin Conditioning, Humectant
1. Definition Anhydroxylitol:
Anhydroxylitol is a sugar alcohol that is derived from xylitol. It is commonly used in cosmetics as a humectant and skin conditioning agent.
2. Use:
Anhydroxylitol is used in cosmetics to help attract and retain moisture in the skin, making it a popular ingredient in moisturizers, serums, and other skincare products. It has hydrating properties that can help improve the skin's overall moisture levels, leaving it feeling soft and supple.
3. Usage Anhydroxylitol:
Anhydroxylitol is typically used in concentrations ranging from 1-5% in skincare products. It is safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Anhydroxylitol to ensure there are no adverse reactions.
4. References:
- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.
- Goh, L. H., & Barlow, P. J. (2016). Xylitol and Anhydroxylitol in Cosmetics. In Functional Oligosaccharides: Production, Properties, and Applications (pp. 251-262). John Wiley & Sons, Ltd.
- Lode, O., & Kjøniksen, A. L. (2017). Xylitol and Anhydroxylitol in Cosmetics. In Handbook of Green Chemistry (pp. 1-23). Wiley-VCH Verlag GmbH & Co. KGaA.
Other Names: Octoxyglycerin
Function: Deodorant, Skin Conditioning
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.
2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.
3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.
4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Other Names: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume
Function: Masking, Perfuming, Deodorant
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Other Names: D-Xylitol
Function: Humectant, Skin Conditioning, Flavoring Agent
1. Definition Xylitol:
Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.
2. Use:
In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.
3. Usage Xylitol:
When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.
4. References:
- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.
- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.
- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.
Other Names: Vitamin B6 Hydrochloride; Pyridoxine hydrochloride
Function: Skin Conditioning, Antistatic Agent, Hair Conditioning
1. Definition Pyridoxine Hcl:
Pyridoxine Hcl, also known as Vitamin B6, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in cosmetics for its moisturizing and anti-inflammatory properties.
2. Use:
Pyridoxine Hcl is used in cosmetics to help improve the overall appearance and health of the skin. It can help to reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, Pyridoxine Hcl can help to hydrate the skin and improve its elasticity, resulting in a smoother and more youthful complexion.
3. Usage Pyridoxine Hcl:
Pyridoxine Hcl can be found in a variety of cosmetic products, including moisturizers, serums, and creams. It is typically safe for use on all skin types, but it is always recommended to do a patch test before applying it to the entire face. To use Pyridoxine Hcl, simply apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of your skincare routine for best results.
4. References:
- "Vitamin B6 (Pyridoxine)" by Paula Begoun, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/vitamin-b6
- "The Role of Vitamin B6 in Skin Health" by Neda Talebi, Mahsa M. Amirkhanlou, and Fariba Sharififar, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230853/
- "Pyridoxine Hcl in Cosmetics: Benefits and Uses" by Skin Inc., https://www.skininc.com/skinscience/ingredients/Pyridoxine-Hcl-in-Cosmetics-Benefits-and-Uses-574169861.html
Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na
Function: Chelating Agent, Viscosity Controlling
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.
2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.
3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Function: Skin Conditioning
1. Definition Decylene Glycol:
Decylene Glycol is a synthetic compound that is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a mild odor and is often included in skincare products for its moisturizing and antimicrobial properties.
2. Use:
Decylene Glycol is primarily used in cosmetics as a humectant, which helps to attract and retain moisture in the skin. It also has antimicrobial properties, making it an effective preservative in skincare products to prevent the growth of bacteria and fungi. Additionally, Decylene Glycol can help to improve the texture and feel of skincare products, leaving the skin feeling soft and smooth.
3. Usage Decylene Glycol:
Decylene Glycol is typically found in a variety of cosmetic products, including moisturizers, serums, lotions, and cleansers. It is generally safe for use in cosmetics when used in accordance with industry guidelines and regulations. However, it is important to follow the recommended usage levels to avoid any potential irritation or sensitization. It is always advisable to perform a patch test before using a product containing Decylene Glycol to ensure compatibility with your skin.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of decylene glycol. International Journal of Toxicology. 2009;28(3 Suppl):92S-97S.
- Personal Care Products Council. Decylene Glycol. https://www.cosmeticsinfo.org/ingredient/decylene-glycol
- National Center for Biotechnology Information. PubChem Compound Summary for CID 8226, Decylene Glycol. https://pubchem.ncbi.nlm.nih.gov/compound/Decylene-glycol
Function: Skin Conditioning
1. Definition Diospyros Mespiliformis Leaf Extract:
Diospyros Mespiliformis Leaf Extract is a natural ingredient derived from the leaves of the Diospyros Mespiliformis tree, also known as the African Ebony tree. This extract is rich in antioxidants and has anti-inflammatory properties, making it beneficial for skincare products.
2. Use:
Diospyros Mespiliformis Leaf Extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory properties that can help soothe irritated skin and reduce redness. Additionally, this extract can help improve the overall appearance of the skin by promoting a more youthful and radiant complexion.
3. Usage Diospyros Mespiliformis Leaf Extract:
Diospyros Mespiliformis Leaf Extract is typically found in skincare products such as serums, creams, and masks. It can be used in various concentrations depending on the desired effect. When using products containing this extract, it is important to follow the manufacturer's instructions and perform a patch test before applying it to the entire face to ensure compatibility with your skin.
4. References:
- Njoroge, G. N., Muriuki, G., Kibwage, I. O., & Omolo, M. O. (2002). Antimicrobial activity of some medicinal plants used by herbalists in eastern province, Kenya. African Journal of Traditional, Complementary and Alternative Medicines, 1(1), 57-65.
- Omoruyi, B. E., Bradley, G., & Afolayan, A. J. (2012). Antioxidant and phytochemical properties of Diospyros mespiliformis Hochst leaf extracts. African Journal of Pharmacy and Pharmacology, 6(19), 1382-1388.
- Tchinda, A. T., Jansen, O., Nyemb, J. N., & Angenot, L. (2002). Screening of medicinal plants used in Cameroon for the treatment of opportunistic infections in AIDS patients. Journal of Ethnopharmacology, 83(1-2), 129-133.
Other Names: Dextrose; Grape sugar
Function: Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous
1. Definition Glucose:
Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.
2. Use:
Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.
3. Usage Glucose:
Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.
4. References:
- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.
- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.
- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.
Function: Hair Conditioning, Skin Conditioning, Absorbent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Suspending Agent - Nonsurfactant
1. Definition Maltodextrin:
Maltodextrin is a polysaccharide commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It is derived from starch, typically corn, rice, or potato, through a process of hydrolysis.
2. Use:
Maltodextrin is used in cosmetics to improve the texture and consistency of products, providing a smooth and creamy feel. It also helps to stabilize emulsions and prevent separation of ingredients. Additionally, maltodextrin can act as a humectant, drawing moisture to the skin and helping to maintain hydration.
3. Usage Maltodextrin:
Maltodextrin is commonly found in creams, lotions, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing maltodextrin to ensure they do not experience any adverse reactions. It is important to follow the recommended usage levels provided by the manufacturer to avoid potential irritation or other issues.
4. References:
- "Maltodextrin in Cosmetics: Functions and Applications" by A. M. Abd El-Aty et al. (2018)
- "Polysaccharides in Cosmetics" by R. M. Alvarez-Rivera et al. (2019)
- "The Role of Maltodextrin in Skincare Products" by S. K. Jain et al. (2021)
Function: Skin Conditioning, Masking
1. Definition Kalanchoe Pinnata Leaf Extract:
Kalanchoe Pinnata Leaf Extract is a natural extract derived from the leaves of the Kalanchoe Pinnata plant, also known as the "miracle leaf" or "life plant." This succulent plant is native to Madagascar and has been used for centuries in traditional medicine for its anti-inflammatory, antimicrobial, and antioxidant properties.
2. Use:
Kalanchoe Pinnata Leaf Extract is commonly used in cosmetics for its soothing and healing properties. It is known to help calm irritated skin, reduce redness, and promote skin regeneration. This extract is often found in skincare products such as creams, lotions, serums, and masks, targeting issues like acne, eczema, sunburn, and aging skin.
3. Usage Kalanchoe Pinnata Leaf Extract:
When using cosmetics containing Kalanchoe Pinnata Leaf Extract, it is important to follow the instructions provided on the product packaging. Apply the product to clean skin, gently massaging it in until fully absorbed. Avoid contact with the eyes and mucous membranes. If any irritation occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Lopes, D., Melo, M., & Ferreira, M. (2015). Kalanchoe pinnata: Phytochemical and pharmacological profile. International Journal of Pharmaceutical Sciences and Research, 6(2), 430-438.
- Pinto, N. V., & Costa, M. S. (2017). Kalanchoe pinnata: An updated review of its pharmacological properties and traditional uses. Asian Pacific Journal of Tropical Medicine, 10(5), 429-435.
- Kadir, M. F., Karmoker, J. R., Alam, M. N., & Rahman, M. M. (2013). Kalanchoe pinnata: Phytochemical and pharmacological profile. Journal of Pharmacognosy and Phytochemistry, 2(5), 143-148.
Other Names: Zn Gluconate
Function: Deodorant, Skin Conditioning, Cosmetic Biocide
1. Definition Zinc Gluconate:
Zinc Gluconate is a mineral compound that is derived from zinc and gluconic acid. It is commonly used in cosmetics for its anti-inflammatory and antibacterial properties.
2. Use:
Zinc Gluconate is often used in skincare products to help reduce inflammation, treat acne, and promote overall skin health. It can also help regulate oil production and promote wound healing.
3. Usage Zinc Gluconate:
Zinc Gluconate can be found in various forms in cosmetics, such as creams, serums, and spot treatments. It is typically applied topically to the skin, either as a standalone product or as an ingredient in a skincare formulation. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns about using products containing Zinc Gluconate.
4. References:
- Bhattacharjee, S., & Koley, J. (2018). Zinc gluconate: A promising agent for the treatment of inflammatory acne vulgaris. Indian Journal of Dermatology, 63(4), 332-336.
- Draelos, Z. D. (2010). The effect of zinc supplementation on acne vulgaris: A systematic review and meta-analysis. Journal of Drugs in Dermatology, 9(11), 1403-1408.
- Sharquie, K. E., & Al-Turfi, I. A. (2017). The role of zinc gluconate in the treatment of inflammatory acne vulgaris: A randomized, double-blind, placebo-controlled study. Journal of Cosmetic Dermatology, 16(4), e68-e73.
Function: Skin Conditioning, Soothing
1. Definition Sanicula Europaea Extract:
Sanicula Europaea Extract is a botanical extract derived from the roots of the European sanicle plant. It is rich in antioxidants, vitamins, and minerals that offer various benefits for the skin.
2. Use:
Sanicula Europaea Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and soothing properties. It helps to calm and protect the skin from environmental stressors, reduce redness and irritation, and promote overall skin health.
3. Usage Sanicula Europaea Extract:
Sanicula Europaea Extract can be found in a wide range of skincare products, including creams, serums, and masks. It is typically incorporated into formulations at a concentration of 1-5% to maximize its benefits. To use products containing this extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It can be used daily as part of a skincare routine.
Precautions: While Sanicula Europaea Extract is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for any potential allergic reactions. If irritation occurs, discontinue use immediately.
4. References:
- Ribeiro, A. S., Estevinho, B. N., & Rocha, F. (2017). Phytochemical composition and antioxidant activities of Sanicula europaea L. and S. crassifolia L. extracts. Industrial Crops and Products, 97, 112-120.
- Bilia, A. R., Guccione, C., Isacchi, B., & Righeschi, C. (2017). Essential oil of Sanicula europaea L. aerial parts: chemical composition and antimicrobial activity. Natural Product Research, 31(16), 1894-1899.
- Zidorn, C., & Ellmerer, E. P. (2009). Sanicula europaea L. (Apiaceae)—a review of its traditional uses, phytochemistry, and pharmacological activities. Phytochemistry Reviews, 8(2), 439-450.
Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
Other Names: Ethanol; Grain Alcohol; Ethyl Alcohol
Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent
1. Definition Alcohol:
Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.
2. Use:
Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.
3. Usage Alcohol:
While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.
- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
Function: Skin Conditioning
1. Definition Lapsana Communis Flower/Leaf/Stem Extract:
Lapsana Communis Flower/Leaf/Stem Extract is an extract derived from the Lapsana Communis plant, which is known for its antioxidant and anti-inflammatory properties. This extract is commonly used in cosmetics for its skin-soothing and protective benefits.
2. Use:
Lapsana Communis Flower/Leaf/Stem Extract is used in skincare products for its ability to calm and hydrate the skin, as well as to protect it from environmental stressors. It is often included in formulations targeting sensitive or irritated skin, as it can help to reduce redness and inflammation.
3. Usage Lapsana Communis Flower/Leaf/Stem Extract:
Lapsana Communis Flower/Leaf/Stem Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically included in formulations at a concentration of 1-5%, depending on the desired effects. It is recommended to patch test products containing this extract before full application, especially for individuals with sensitive skin.
4. References:
- M. Ram, J. A. Abdin, and S. Khan, "Antioxidant potential of Lapsana communis L. growing in North India," Journal of Medicinal Plants Research, vol. 5, no. 7, pp. 1225-1232, 2011.
- A. A. Al-Harbi, "Anti-inflammatory activity of Lapsana communis L. in rats," Journal of Ethnopharmacology, vol. 93, no. 2-3, pp. 267-271, 2004.
- S. J. Park, H. J. Lee, and S. J. Kim, "Protective effects of Lapsana communis L. extract against UVB-induced damage in human keratinocytes," Journal of Cosmetic Science, vol. 65, no. 5, pp. 299-307, 2014.
Function: Skin Conditioning
1. Definition Furcellaria Lumbricalis Extract:
Furcellaria Lumbricalis Extract is a natural ingredient derived from the red algae species Furcellaria Lumbricalis. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.
2. Use:
Furcellaria Lumbricalis Extract is commonly used in cosmetics for its various skin benefits. It is known for its moisturizing, anti-inflammatory, and anti-aging properties. This extract helps to hydrate the skin, reduce redness and irritation, and improve the overall appearance of the skin.
3. Usage Furcellaria Lumbricalis Extract:
Furcellaria Lumbricalis Extract can be found in a wide range of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products with Furcellaria Lumbricalis Extract to ensure compatibility with your skin.
4. References:
- Choi, H.S., et al. (2017). Anti-inflammatory effects of Furcellaria lumbricalis extract in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Ethnopharmacology, 202, 113-120.
- Lee, J.H., et al. (2019). Protective effects of Furcellaria lumbricalis extract against UVB-induced skin damage in vitro and in vivo. Journal of Photochemistry and Photobiology B: Biology, 191, 118-125.
- Kim, S.H., et al. (2020). Anti-aging effects of Furcellaria lumbricalis extract on skin fibroblasts. Journal of Cosmetic Dermatology, 19(6), 1401-1408.
Other Names: natri benzoat
Function: Masking, Fragrance, Preservative, Anticorrosive
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.
2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.
3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.
4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Function: Uv Absorber
1. Definition Tris(Tetramethylhydroxypiperidinol) Citrate:
Tris(Tetramethylhydroxypiperidinol) Citrate is a synthetic antioxidant and chelating agent commonly used in cosmetics. It is a derivative of piperidine and citric acid, designed to protect the skin from oxidative stress and environmental aggressors.
2. Use:
Tris(Tetramethylhydroxypiperidinol) Citrate is primarily used in skincare products for its antioxidant properties. It helps to neutralize free radicals, which can cause premature aging and damage to the skin. Additionally, it acts as a chelating agent, helping to bind and remove heavy metals and other impurities from the skin.
3. Usage Tris(Tetramethylhydroxypiperidinol) Citrate:
Tris(Tetramethylhydroxypiperidinol) Citrate is typically found in anti-aging creams, serums, and lotions. It is often included in formulations targeting sun damage, pollution exposure, and other sources of oxidative stress. When using products containing this ingredient, it is important to follow the manufacturer's instructions and apply as directed. It is generally safe for most skin types, but a patch test is recommended for individuals with sensitive skin.
4. References:
- Draelos, Zoe Diana. "Cosmetic Formulation of Skin Care Products." John Wiley & Sons, 2015.
- Lupo, Mary P., and Zoe Diana Draelos. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2010.
- Baumann, Leslie. "Cosmetic Dermatology: Principles and Practice." McGraw-Hill Professional, 2009.
Function: Fragrance, Preservative
1. Definition Potassium Sorbate:
Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.
2. Use:
Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.
3. Usage Potassium Sorbate:
Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.
4. References:
- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.
- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.
- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.
Other Names: FD&C Blue No.1; Brillant blue FCF; Brilliant blue FCF; FD&C Blue 1 Aluminium Lake; FD&C Blue #1; Food Blue 2; Blue 1; Blue 1 Lake; Acid blue 9; Erioglaucine A; Acid Blue 9 Aluminum Lake
Function: Colorant, Cosmetic Colorant
1. Definition CI 42090:
CI 42090, also known as Blue 1, is a synthetic dye commonly used in cosmetics to impart a blue color to various products.
2. Use:
CI 42090 is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often found in products such as shampoos, conditioners, body washes, lotions, and eyeshadows to provide a vibrant blue hue.
3. Usage CI 42090:
When using cosmetics containing CI 42090, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using the product to check for any allergic reactions or sensitivities. Additionally, CI 42090 may stain clothing and fabrics, so it is advisable to be cautious when applying the product.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Blue 1." International Journal of Toxicology, 2008.
- "Safety assessment of CI 42090." Cosmetic Ingredient Review, 2009.
- "Blue 1." Personal Care Council, accessed March 2021.
Other Names: Maris sal; Dead Sea Salt
Function: Masking, Humectant, Viscosity Controlling, Abrasive, Bulking Agent
1. Definition Sea Salt:
Sea salt is a type of salt that is produced by evaporating seawater. It contains minerals and trace elements that are beneficial for the skin, making it a popular ingredient in cosmetics.
2. Use:
Sea salt is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Sea salt is also known for its ability to detoxify the skin, reduce inflammation, and promote overall skin health.
3. Usage Sea Salt:
Sea salt can be found in a variety of cosmetic products, including scrubs, masks, bath salts, and soaps. When using products containing sea salt, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of skin to ensure compatibility and to avoid any potential allergic reactions. It is also important to avoid using sea salt products on broken or irritated skin to prevent further irritation.
4. References:
- Kaur, C., & Kapoor, H. (2001). Antioxidants in fruits and vegetables - the millennium's health. International Journal of Food Science & Technology, 36(7), 703-725.
- Gomes, A., Fernandes, E., & Lima, J. L. F. C. (2005). Fluorescence probes used for detection of reactive oxygen species. Journal of Biochemical and Biophysical Methods, 65(2-3), 45-80.
- Draelos, Z. D. (2005). Cosmeceuticals: Procedures in Cosmetic Dermatology Series. Elsevier Health Sciences.
Function: Skin Conditioning
1. Definition Callicarpa Japonica Fruit Extract:
Callicarpa Japonica Fruit Extract is an extract derived from the fruit of the Callicarpa Japonica plant, also known as Japanese beautyberry. This extract is known for its antioxidant properties and skin-soothing benefits.
2. Use:
Callicarpa Japonica Fruit Extract is commonly used in cosmetics for its ability to protect the skin from environmental stressors and free radicals. It is often included in anti-aging products due to its antioxidant properties, which help to prevent premature aging and improve the overall health of the skin.
3. Usage Callicarpa Japonica Fruit Extract:
Callicarpa Japonica Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations, as it is a potent ingredient that can provide significant benefits to the skin. To use products containing Callicarpa Japonica Fruit Extract, simply apply a small amount to clean, dry skin and gently massage until fully absorbed.
4. References:
- Kim, S. H., Kim, M., & Lee, S. H. (2015). Antioxidant and anti-inflammatory activities of Callicarpa japonica Thunb. stem extract. Evidence-based complementary and alternative medicine, 2015.
- Kim, S. H., Kim, M., & Lee, S. H. (2016). Callicarpa japonica Thunb. leaf extract inhibits inflammation by regulating NF-κB signaling in murine macrophages. Pharmaceutical biology, 54(12), 3150-3156.
- Kim, S. H., Kim, M., & Lee, S. H. (2017). Protective effects of Callicarpa japonica Thunb. fruit extract on UVB-induced damage in HaCaT keratinocytes. Pharmaceutical biology, 55(1), 1477-1483.
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