Cleanface Phyto Stem Cell Serum - Ingredient Explanation
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Function: Solvent
1. Definition Methylpropanediol:
Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.
2. Use:
Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.
3. Usage Methylpropanediol:
When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.
4. References:
- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.
- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.
- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.
Other Names: Nicotinic acid amide; Nicotinamide
Function: Hair Conditioning, Skin Conditioning, Smoothing
1. Definition Niacinamide:
Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.
2. Use:
Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.
3. Usage Niacinamide:
Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.
Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.
4. References:
- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.
- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.
- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.
Function: Solvent, Skin Conditioning
1. Definition Pentylene Glycol:
Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.
2. Use:
Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.
3. Usage Pentylene Glycol:
Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.
4. References:
- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.
- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.
- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.
Function: Masking
1. Definition Aloe Barbadensis Leaf Water:
Aloe Barbadensis Leaf Water, also known as Aloe Vera leaf water, is a natural ingredient derived from the leaves of the Aloe Barbadensis plant. It is known for its soothing and hydrating properties, making it a popular ingredient in skincare and cosmetic products.
2. Use:
Aloe Barbadensis Leaf Water is commonly used in cosmetics for its moisturizing, calming, and healing properties. It helps to hydrate the skin, reduce inflammation, and promote healing of wounds and sunburns. It is also known to have antioxidant and antibacterial properties, making it beneficial for acne-prone skin. Additionally, Aloe Barbadensis Leaf Water is gentle enough for sensitive skin and can help to soothe irritation and redness.
3. Usage Aloe Barbadensis Leaf Water:
Aloe Barbadensis Leaf Water can be found in a variety of skincare and cosmetic products, such as moisturizers, serums, masks, and sunscreens. It can be applied directly to the skin or used as an ingredient in various formulations. To use Aloe Barbadensis Leaf Water, simply apply the product containing the ingredient to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of a skincare routine.
4. References:
- Lee, S. H., An, S. M., Choi, K. H., Moon, S. W., Park, Y. D., & Kim, S. Z. (2015). Aloe vera gel suppresses the UVB-induced skin photoaging through inhibition of collagenase in human dermal fibroblasts. Journal of Cosmetic Dermatology, 14(4), 291-297.
- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: a short review. Indian Journal of Dermatology, 53(4), 163-166.
- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21-26.
Other Names: cremophor rh-40
Function: Perfuming, Fragrance, Emulsifying, Surfactant
1. Definition Peg 40 Hydrogenated Castor Oil:
Peg 40 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.
2. Use:
Peg 40 Hydrogenated Castor Oil is used in cosmetics to help blend together ingredients that are normally difficult to mix, such as oil and water. It also helps to stabilize formulations and improve the texture of products.
3. Usage Peg 40 Hydrogenated Castor Oil:
Peg 40 Hydrogenated Castor Oil is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is often found in creams, lotions, serums, and other skincare products. It should be added to the oil phase of a formulation and heated to ensure proper dispersion.
Precautions: While Peg 40 Hydrogenated Castor Oil is considered safe for use in cosmetics, some individuals may be sensitive to it. It is always recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. Additionally, some studies have raised concerns about the potential for PEG compounds to be contaminated with harmful impurities, so it is important to use products from reputable sources.
4. References:
- "PEG-40 Hydrogenated Castor Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-40-hydrogenated-castor-oil.
- "PEG-40 Hydrogenated Castor Oil." Truth In Aging, www.truthinaging.com/ingredients/peg-40-hydrogenated-castor-oil.
- "PEG-40 Hydrogenated Castor Oil." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/surfactants/peg-40-hydrogenated-castor-oil.
Function: Skin Conditioning, Emollient, Emulsifying, Surfactant
1. Definition Peg 7 Glyceryl Cocoate:
Peg 7 Glyceryl Cocoate is a mild, non-ionic surfactant derived from coconut oil and polyethylene glycol. It is commonly used in cosmetics as an emollient and emulsifier.
2. Use:
Peg 7 Glyceryl Cocoate is used in various cosmetic products such as cleansers, shampoos, and conditioners. It helps to cleanse the skin and hair by removing dirt and impurities while also providing moisturizing benefits. Additionally, it helps to create a smooth and creamy texture in formulations.
3. Usage Peg 7 Glyceryl Cocoate:
When using products containing Peg 7 Glyceryl Cocoate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is recommended to avoid contact with the eyes and to rinse thoroughly if contact occurs.
4. References:
- Paula Begoun. (2003). "The Complete Beauty Bible: The Ultimate Guide to Smart Beauty." Rodale Books.
- Personal Care Products Council. (2015). "International Cosmetic Ingredient Dictionary and Handbook." Washington, DC: Personal Care Products Council.
- G. Wypych. (2016). "Handbook of Surfactants." ChemTec Publishing.
Other Names: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol
Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.
2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.
3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.
4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Other Names: Hyaluronic Acid Sodium Salt; Kopuron
Function: Humectant, Skin Conditioning
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.
2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.
3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.
Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Other Names: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol
1. Definition Bisabolol:
Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.
2. Use:
Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.
3. Usage Bisabolol:
Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.
4. References:
- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.
- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.
- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.
Other Names: Maolate
Function: Preservative, Antimicrobial, Cosmetic Biocide
1. Definition Chlorphenesin:
Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.
2. Use:
Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.
3. Usage Chlorphenesin:
Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.
- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.
- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Other Names: Glyoxyldiureide; Allantion
Function: Skin Protecting, Skin Conditioning, Soothing
1. Definition Allantoin:
Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.
2. Use:
Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.
3. Usage Allantoin:
Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.
4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.
- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.
Other Names: Carboxypolymethylene; Carbopol; Cabomer
Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming
1. Definition Carbomer:
Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.
2. Use:
Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.
3. Usage Carbomer:
When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.
4. References:
- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.
- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.
- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.
Other Names: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate
Function: Chelating Agent
1. Definition Tetrasodium Edta:
Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.
2. Use:
Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.
3. Usage Tetrasodium Edta:
Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.
- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/
- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751
Other Names: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer
Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.
2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.
3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.
4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Function: Skin Protecting
1. Definition Laminaria Digitata Extract:
Laminaria Digitata Extract is a type of seaweed extract derived from the brown algae Laminaria Digitata. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.
2. Use:
Laminaria Digitata Extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has anti-inflammatory properties that can help calm irritated skin and reduce redness.
3. Usage Laminaria Digitata Extract:
Laminaria Digitata Extract is typically found in skincare products such as moisturizers, serums, and masks. It is best applied to clean skin, either alone or as part of a skincare routine. It can be used daily or as needed, depending on the product instructions and individual skin concerns. It is important to perform a patch test before using products containing Laminaria Digitata Extract to ensure compatibility with your skin.
4. References:
- Duarte ME, Noseda MD, Noseda DG, Tulio S, Pujol CA, Damonte EB. Inhibitory effect of sulfated galactans from the marine alga Bostrychia montagnei on herpes simplex virus replication in vitro. Phytomedicine. 2001 Nov;8(6):53-8. doi: 10.1078/0944-7113-00058. PMID: 11710719.
- Wijesinghe WA, Jeon YJ. Enzyme-assistant extraction (EAE) of bioactive components: a useful approach for recovery of industrially important metabolites from seaweeds: a review. Fitoterapia. 2012 Apr;83(1):6-12. doi: 10.1016/j.fitote.2011.10.006. Epub 2011 Oct 19. PMID: 22036656.
- Zaporozhets TS, Besednova NN, Kuznetsova TA, Zviagintseva TN, Makarenkova ID, Kryzhanovskii SP. [The effect of fucoidan from the brown alga Fucus evanescens on the activity of the proteolytic enzymes of the blood in cancer]. Vopr Onkol. 1996;42(2):225-30. Russian. PMID: 8651167.
Other Names: L-Sodium Lactate
Function: Humectant, pH adjusting agent, Exfoliant, Keratolytic
1. Definition Sodium Lactate:
Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.
2. Use:
Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.
3. Usage Sodium Lactate:
When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.
4. References:
- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.
- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
Other Names: 2-hydroxypropanoic Acid; Milk Acid
Function: Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant
1. Definition Lactic Acid:
Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.
2. Use:
Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.
3. Usage Lactic Acid:
When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.
- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.
Function: Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent
1. Definition Serine:
Serine is an amino acid that is essential for the production of proteins and is a key component in the synthesis of various molecules in the body. In cosmetics, serine is often used for its moisturizing and skin-conditioning properties.
2. Use:
Serine is commonly found in skincare products such as moisturizers, serums, and lotions due to its ability to help maintain skin hydration and improve skin texture. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.
3. Usage Serine:
When using products containing serine, it is important to follow the instructions provided by the manufacturer. Serine is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergic reactions. It is recommended to consult with a dermatologist or skincare professional if you have any concerns about using products with serine.
4. References:
- Y. Katsuta, M. Iida, K. Hotta, S. Tsuboi, Y. Ogawa, "Involvement of serine proteases in the pathogenesis of rosacea: a preliminary study," Archives of Dermatological Research, vol. 300, no. 3, pp. 153-157, 2008.
- N. K. Jain, A. Roy, "Serine protease inhibitors in skin disorders," European Journal of Pharmaceutical Sciences, vol. 11, no. 1, pp. 1-9, 2000.
- S. P. Han, J. Y. Lee, H. S. Kim, "Effects of serine on skin barrier function and inflammation in atopic dermatitis," Journal of Dermatology, vol. 42, no. 2, pp. 123-131, 2015.
Other Names: Carbonyl diamide; Carbamide
Function: Skin Conditioning, Humectant, Antistatic Agent, pH adjusting agent
1. Definition Urea:
Urea is a naturally occurring substance found in the human body and is also synthetically produced for use in various cosmetic products. It is a humectant that helps to draw moisture into the skin and is known for its hydrating properties.
2. Use:
Urea is commonly used in skincare products such as moisturizers, creams, and lotions due to its ability to help improve skin hydration. It is especially beneficial for individuals with dry or dehydrated skin, as it can help to soften and smooth the skin's surface.
3. Usage Urea:
When using skincare products containing urea, it is important to follow the instructions provided on the product packaging. It is recommended to start with a small amount of product and gradually increase the frequency of use to prevent any potential skin irritation. Individuals with sensitive skin should perform a patch test before applying urea-containing products to a larger area of the skin.
4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.
- Loden, M., & Maibach, H. I. (2005). Dry skin and moisturizers: chemistry and function. CRC Press.
Other Names: D-Glucitol
Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer
1. Definition Sorbitol:
Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.
2. Use:
Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.
3. Usage Sorbitol:
Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.
4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol
- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol
- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol
Other Names: NaCl; Natrum muriaticum
Function: Masking, Viscosity Controlling, Bulking Agent
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.
2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.
3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Function: pH adjusting agent, pH adjusting agent
1. Definition Aminomethyl Propanol:
Aminomethyl Propanol, also known as AMP, is a neutralizing agent used in cosmetics and personal care products. It is a clear liquid with an ammonia-like odor and is commonly used to adjust the pH levels in various products.
2. Use:
Aminomethyl Propanol is primarily used in hair care products such as hair dyes, hair sprays, and hair styling gels. It helps to stabilize the pH of these products, ensuring they are safe and effective for use on the hair and scalp. Additionally, AMP can also be found in skincare products like creams and lotions to regulate the pH levels and enhance the overall performance of the product.
3. Usage Aminomethyl Propanol:
When using products containing Aminomethyl Propanol, it is important to follow the instructions provided on the packaging. Avoid direct contact with the eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any allergic reactions.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Safety Assessment of Aminomethyl Propanol as Used in Cosmetics." International Journal of Toxicology, vol. 26, no. 4, 2007, pp. 27S-39S.
- "Aminomethyl Propanol." The Personal Care Products Council, www.cosmeticsinfo.org/ingredient/aminomethyl-propanol. Accessed 10 Nov. 2021.
- "AMP." Cosmetics and Toiletries, www.cosmeticsandtoiletries.com/formulating/category/haircare/AMP-284115661.html. Accessed 10 Nov. 2021.
Other Names: Ceramide 3; Ceramide III
1. Definition Ceramide Np:
Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.
2. Use:
Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.
3. Usage Ceramide Np:
Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.
4. References:
- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.
- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.
- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.
Function: Skin Conditioning
1. Definition Buddleja Davidii Meristem Cell Culture:
Buddleja Davidii Meristem Cell Culture refers to the culture of plant cells derived from the meristems of Buddleja Davidii, commonly known as the butterfly bush. Meristems are regions of plant tissue that contain undifferentiated cells capable of continuous division, making them valuable for the production of plant-based cosmetic ingredients.
2. Use:
Buddleja Davidii Meristem Cell Culture is used in cosmetics for its antioxidant, anti-inflammatory, and anti-aging properties. The plant cells contain active compounds such as flavonoids, phenylethanoids, and iridoids, which help protect the skin from environmental damage, reduce inflammation, and promote collagen production.
3. Usage Buddleja Davidii Meristem Cell Culture:
Buddleja Davidii Meristem Cell Culture is commonly incorporated into skincare products such as serums, creams, and masks. It is known for its ability to improve skin elasticity, reduce the appearance of wrinkles, and enhance overall skin health. When using products containing this ingredient, it is important to follow the manufacturer's instructions and discontinue use if any irritation occurs.
4. References:
- Kim, Y. J., Uyama, H., & Kobayashi, S. (2006). Inhibition effects of Buddleja officinalis on melanin biosynthesis. Natural product research, 20(1), 86-90.
- Li, W., Li, Y., & Yang, R. (2012). Antioxidant activity of extracts and fractions from Buddleja davidii. Food chemistry, 134(4), 2040-2046.
- Lee, S. H., & Kim, J. K. (2013). Buddleja officinalis extract inhibits UV-B-induced matrix metalloproteinase-1 expression in human dermal fibroblasts. Journal of medicinal food, 16(6), 511-517.
Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
