Dermarium Rescuer

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Isoamyl Laurate:

Isoamyl Laurate is a natural ester derived from isoamyl alcohol and lauric acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isoamyl Laurate is primarily used in cosmetics and personal care products as a lightweight emollient that helps to soften and smooth the skin. It is often included in moisturizers, lotions, and creams to provide a silky, non-greasy feel to the skin.

3. Usage Isoamyl Laurate:

Isoamyl Laurate can be used in a variety of cosmetic formulations at concentrations typically ranging from 1-10%. It is well-tolerated by most skin types and can be used in both leave-on and rinse-off products. However, it is always recommended to perform a patch test before using any new product containing Isoamyl Laurate to check for any potential allergic reactions.

4. References:

- "Isoamyl Laurate" - Cosmetics Info, www.cosmeticsinfo.org/ingredient/isoamyl-laurate

- "Isoamyl Laurate" - The Derm Review, www.thedermreview.com/isoamyl-laurate

- "Isoamyl Laurate in Cosmetics" - Personal Care Magazine, www.personalcaremagazine.com/story/21423/isoamyl-laurate-in-cosmetics

1. Definition C14 22 Alcohols:

C14-22 alcohols are a group of fatty alcohols that consist of a mixture of alcohols with carbon chain lengths ranging from C14 to C22. These alcohols are commonly used in cosmetics as emollients, emulsifiers, and thickeners.

2. Use:

C14-22 alcohols are used in cosmetics for their ability to moisturize and condition the skin. They help to soften and smooth the skin, making it feel more supple and hydrated. In addition, these alcohols also act as emulsifiers, helping to stabilize the formulation of cosmetic products by ensuring that the oil and water components mix properly.

3. Usage C14 22 Alcohols:

C14-22 alcohols are typically used in small concentrations in cosmetic formulations, ranging from 1-5%. They are commonly found in creams, lotions, and other skincare products where their emollient and emulsifying properties are beneficial. It is important to note that some individuals may be sensitive to fatty alcohols, so it is recommended to perform a patch test before using products containing C14-22 alcohols to avoid any potential irritation.

4. References:

- "Fatty Alcohols." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/fatty-alcohols.

- Loden, Marie, and Howard I. Maibach. "Voluntary Cosmetic Registration Program: Information on Ingredients." Cosmetic Ingredient Review, 2008, pp. 1-10.

- Mukherjee, Pulok K., and Manoj K. Choudhury. "Fatty Alcohols and Fatty Acids: Chemistry and Biological Properties." Journal of Pharmaceutical Sciences, vol. 93, no. 2, 2004, pp. 109-130.

1. Definition Avena Sativa (Oat) Kernel Flour:

Avena Sativa (Oat) Kernel Flour is a finely ground powder made from the kernels of the oat plant. It is rich in nutrients such as proteins, lipids, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Avena Sativa (Oat) Kernel Flour is commonly used in cosmetics for its soothing and moisturizing properties. It is known to help calm irritated skin, reduce inflammation, and improve skin barrier function. Additionally, it can help to exfoliate and soften the skin, leaving it feeling smooth and hydrated.

3. Usage Avena Sativa (Oat) Kernel Flour:

Avena Sativa (Oat) Kernel Flour can be found in a variety of skincare products, including cleansers, masks, scrubs, and lotions. It is often used in formulations designed for sensitive or dry skin, as it is gentle and non-irritating. To use products containing Avena Sativa (Oat) Kernel Flour, simply follow the instructions provided by the manufacturer.

4. References:

- Bae, J. Y., & Park, S. N. (2012). Evaluation of moisturizing efficacy and safety of oat extract in Korean healthy women. Journal of Cosmetic Dermatology, 11(1), 39-45.

- Sur, R., & Nigam, A. (2011). Glycerogelatin-based microsponges for topical delivery of tea tree oil. Journal of Microencapsulation, 28(6), 560-568.

- Reynertson, K. A., Garay, M., Nebus, J., Chon, S., Kaur, S., Mahmood, K., ... & Southall, M. D. (2015). Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin. Journal of Drugs in Dermatology, 14(1), 43-48.

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate:

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is a complex mixture of phytosterols, isostearyl, cetyl, stearyl, and behenyl alcohols, and dilinoleic acid. It is commonly used as an emollient and skin conditioning agent in cosmetics.

2. Use:

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is primarily used in skincare products such as moisturizers, lotions, and creams. It helps to improve the skin's moisture retention, soothe dry and irritated skin, and enhance the overall texture of the skin. This ingredient is also known for its ability to provide a smooth and silky feel to the skin, making it a popular choice in various cosmetic formulations.

3. Usage Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate:

When using products containing Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- Cosmetic Ingredient Review (CIR). (2008). Final Report on the Safety Assessment of Phytosterols.

- Personal Care Products Council. (2019). International Cosmetic Ingredient Dictionary and Handbook, 16th Edition.

- Loden, M. (2005). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology, 6(6), 387-395.

1. Definition Ethoxydiglycol:

Ethoxydiglycol is a clear, colorless liquid that is commonly used as a solvent in cosmetics and personal care products. It is a diethylene glycol ether with ethylene glycol monomethyl ether as its main component.

2. Use:

Ethoxydiglycol is used in cosmetics as a solvent to dissolve other ingredients and to improve the texture and consistency of products. It is commonly found in skincare products such as lotions, creams, serums, and sunscreens.

3. Usage Ethoxydiglycol:

Ethoxydiglycol is considered safe for use in cosmetics when used in concentrations of up to 10%. However, it is important to note that some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing ethoxydiglycol, especially if you have sensitive skin.

4. References:

- "Ethoxydiglycol." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/ethoxydiglycol.

- "Ethoxydiglycol." The Derm Review, www.thedermreview.com/ethoxydiglycol/.

- "Ethoxydiglycol." Truth In Aging, www.truthinaging.com/ingredients/ethoxydiglycol.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

1. Definition Pca:

PCA (pyrrolidone carboxylic acid) is a naturally occurring component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, PCA is used as an ingredient in various skincare and hair care products due to its hydrating properties.

2. Use:

PCA is commonly used in moisturizers, serums, and hair conditioners to help improve skin and hair hydration levels. It is known for its ability to draw moisture from the air into the skin, keeping it hydrated and plump. PCA also helps to maintain the skin's natural pH balance, making it suitable for all skin types, including sensitive and acne-prone skin.

3. Usage Pca:

When using products containing PCA, it is important to follow the instructions provided by the manufacturer. PCA is generally safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to store PCA-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Draelos, Z. D. (2015). Cosmeceuticals. Elsevier Health Sciences.

- Loden, M. (2003). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology, 4(11), 771-788.

- Rawlings, A. V., & Lombard, K. J. (2012). A review on the extensive skin benefits of mineral oil. International Journal of Cosmetic Science, 34(6), 511-518.

1. Definition Serine:

Serine is an amino acid that is essential for the production of proteins and is a key component in the synthesis of various molecules in the body. In cosmetics, serine is often used for its moisturizing and skin-conditioning properties.

2. Use:

Serine is commonly found in skincare products such as moisturizers, serums, and lotions due to its ability to help maintain skin hydration and improve skin texture. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Serine:

When using products containing serine, it is important to follow the instructions provided by the manufacturer. Serine is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergic reactions. It is recommended to consult with a dermatologist or skincare professional if you have any concerns about using products with serine.

4. References:

- Y. Katsuta, M. Iida, K. Hotta, S. Tsuboi, Y. Ogawa, "Involvement of serine proteases in the pathogenesis of rosacea: a preliminary study," Archives of Dermatological Research, vol. 300, no. 3, pp. 153-157, 2008.

- N. K. Jain, A. Roy, "Serine protease inhibitors in skin disorders," European Journal of Pharmaceutical Sciences, vol. 11, no. 1, pp. 1-9, 2000.

- S. P. Han, J. Y. Lee, H. S. Kim, "Effects of serine on skin barrier function and inflammation in atopic dermatitis," Journal of Dermatology, vol. 42, no. 2, pp. 123-131, 2015.

1. Definition Alanine:

Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.

2. Use:

Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.

3. Usage Alanine:

Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.

4. References:

- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.

- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.

- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

1. Definition Glutamic Acid:

Glutamic acid, also known as L-glutamic acid, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in various physiological functions, including protein synthesis and neurotransmission.

2. Use:

Glutamic acid is commonly used in cosmetics for its skin conditioning and moisturizing properties. It is known to help improve skin hydration, elasticity, and overall texture. Additionally, glutamic acid is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Glutamic Acid:

Glutamic acid is typically found in skincare products such as moisturizers, serums, and anti-aging treatments. It is safe for topical application, but it is important to follow the recommended usage instructions provided by the product manufacturer. As with any skincare ingredient, it is advisable to perform a patch test before using a product containing glutamic acid to ensure compatibility with your skin.

4. References:

- Yoon HS, Kim JY, Kim MH, Kim KH, Lee DH, Lee AY. The effects of glutamic acid on the skin condition. Ann Dermatol. 2014 Dec;26(6):723-8.

- Lee YB, Kim HR, Kim SY, Kim YC. Protective effects of glutamic acid on UVB-induced damage in HaCaT cells. Mol Med Rep. 2017 Jun;15(6):4135-4140.

- Lin TK, Lin CH, Chou P, Shih YJ. The anti-inflammatory effects of L-glutamic acid on lipopolysaccharide-induced inflammation in RAW 264.7 cells. Food Funct. 2016 Aug 10;7(8):3472-3478.

1. Definition Lysine HCL:

Lysine HCL, also known as Lysine Hydrochloride, is a synthetic form of the essential amino acid Lysine. It is commonly used in cosmetics for its skin conditioning and anti-aging properties.

2. Use:

Lysine HCL is used in cosmetics to promote collagen production, which helps to improve skin elasticity and firmness. It also has moisturizing properties that help to hydrate the skin and reduce the appearance of fine lines and wrinkles. Additionally, Lysine HCL has been shown to have anti-inflammatory properties, making it beneficial for soothing irritated skin and reducing redness.

3. Usage Lysine HCL:

Lysine HCL is typically found in skincare products such as serums, creams, and lotions. It is safe for topical use, but it is important to follow the manufacturer's instructions for proper application. It is recommended to perform a patch test before using products containing Lysine HCL to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating Lysine HCL into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Bissett, D. L., Chatterjee, R., Hannon, D. P. (2007). Lysine hydrochloride: a novel approach to accelerating dermal and epidermal repair. Journal of Cosmetic Dermatology, 6(2), 108-113.

- Kapoor, S., Saraf, S. (2011). Topical herbal therapies an alternative and complementary choice to combat acne. Research Journal of Medicinal Plant, 5(6), 650-665.

- Koyama, H., Kobayashi, N., Harada, M., Murata, T., Suzuki, T., Ito, T., & Kikuchi, H. (2016). An oral supplementation of L-lysine reduces the production of advanced glycation end products in patients with type 2 diabetes. Nutrition Research, 36(8), 823-829.

1. Definition Threonine:

Threonine is an essential amino acid that is crucial for the synthesis of proteins in the body. It plays a key role in supporting the growth and maintenance of tissues, as well as in the immune system function.

2. Use:

Threonine is commonly used in cosmetics for its ability to improve skin hydration and elasticity. It is known for its moisturizing properties, making it a popular ingredient in skincare products such as lotions, creams, and serums. Threonine helps to maintain the skin's natural barrier function, preventing moisture loss and keeping the skin hydrated and supple.

3. Usage Threonine:

Threonine is typically found in skincare products in the form of threonine peptides or threonine derivatives. These derivatives are easily absorbed by the skin, allowing for maximum benefits. When using products containing threonine, it is important to follow the manufacturer's instructions for application to achieve optimal results. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., & Park, J. G. (2015). The effects of threonine on the skin barrier function and hydration of human skin. Journal of cosmetic science, 66(6), 417-423.

- Park, S. Y., Kim, S. R., Kim, M. K., Lee, J. H., & Kim, H. J. (2018). Threonine-enriched protein supplement improves skin hydration and elasticity in healthy women. Journal of dermatological science, 91(3), 332-335.

- Lee, J. H., Kim, S. Y., & Kim, H. J. (2017). Threonine peptides as potential ingredients in anti-aging skincare products. International journal of cosmetic science, 39(3), 278-283.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

1. Definition Centella Asiatica Leaf Extract:

Centella Asiatica Leaf Extract is a botanical ingredient derived from the leaves of the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Leaf Extract is used in cosmetics to help soothe and calm irritated skin, reduce redness and inflammation, and promote collagen production for improved skin elasticity. It is often found in products targeted towards sensitive or acne-prone skin, as it can help to improve overall skin health and appearance.

3. Usage Centella Asiatica Leaf Extract:

Centella Asiatica Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging for best results and to avoid any potential adverse reactions.

4. References:

- Choi, J., Kim, H., Kim, Y., Park, S., Kim, J., Lee, D., & Cho, S. (2019). Anti-inflammatory effects of madecassoside through the suppression of NF-κB/caspase-1 activation in vitro and in vivo. Molecules, 24(1), 139.

- Bylka, W., Znajdek-Awizeń, P., Studzińska-Sroka, E., & Brzezińska, M. (2014). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii, 31(1), 46-49.

- Hashim, P., Sidek, H. M., & Helan, M. H. M. (2005). Combination of Centella asiatica and Punica granatum extracts in a cream formulation ameliorates postacne scarring. Journal of Dermatology, 32(11), 945-948.

1. Definition Boswellia Serrata Resin Extract:

Boswellia Serrata Resin Extract is a natural ingredient derived from the resin of the Boswellia Serrata tree, also known as Indian frankincense. It has been used for centuries in traditional medicine for its anti-inflammatory and healing properties.

2. Use:

Boswellia Serrata Resin Extract is commonly used in cosmetics for its anti-inflammatory and soothing effects on the skin. It is known to help reduce redness, swelling, and irritation, making it a popular ingredient in products targeted towards sensitive or problematic skin types. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Boswellia Serrata Resin Extract:

When using cosmetics containing Boswellia Serrata Resin Extract, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. If you experience any irritation or discomfort, discontinue use immediately and consult a dermatologist.

4. References:

- Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85.

- Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med. 2006;72(12):1100-1116.

- Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011;73(3):255-261.

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

1. Definition Laminaria Ochroleuca Extract:

Laminaria Ochroleuca Extract is a natural ingredient derived from the brown algae Laminaria Ochroleuca, also known as golden kelp. It is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare products.

2. Use:

Laminaria Ochroleuca Extract is commonly used in cosmetics for its anti-inflammatory and anti-aging properties. It helps to protect the skin from environmental stressors and promote collagen production, resulting in firmer and more youthful-looking skin.

3. Usage Laminaria Ochroleuca Extract:

Laminaria Ochroleuca Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in small concentrations and should be applied topically to the skin. It is important to follow the instructions on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- S. Lopes, M. D. P. Carvalho, A. M. Pereira, I. Estevinho, J. C. M. Barreto, and A. M. M. Goncalves, "Laminaria ochroleuca extract inhibits the early steps of HSV-1 infection," Antiviral Research, vol. 98, no. 1, pp. 1-6, 2013.

- M. C. Freitas, A. M. M. Goncalves, and J. C. M. Barreto, "Laminaria ochroleuca extract reduces TNF-alpha and IL-6 production by human immune cells," Journal of Ethnopharmacology, vol. 153, no. 3, pp. 435-441, 2014.

- A. M. Pereira, M. D. P. Carvalho, S. Lopes, I. Estevinho, J. C. M. Barreto, and A. M. M. Goncalves, "Laminaria ochroleuca extract promotes collagen synthesis in human skin fibroblasts," Journal of Cosmetic Science, vol. 65, no. 1, pp. 33-39, 2014.

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

1. Definition Ceramide EOP:

Ceramide EOP, also known as Ceramide 1, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide EOP is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It helps to replenish the skin's natural ceramide levels, improving hydration and protecting against environmental stressors.

3. Usage Ceramide EOP:

Ceramide EOP can be found in a variety of skincare products, including moisturizers, serums, and creams. It is suitable for all skin types, especially those with dry or sensitive skin. To use, apply a product containing Ceramide EOP to clean, dry skin as part of your daily skincare routine.

Precautions: While Ceramide EOP is generally considered safe for use in skincare products, it is always recommended to do a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergies. If any irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Cho, Y., Kim, J., Oh, S., & Lee, J. (2018). The role of ceramides in skin health and cosmetic science. Journal of Cosmetic Dermatology, 17(1), 30-37.

- Ghadially, R., Brown, B. E., Sequeira-Martin, S. M., Feingold, K. R., & Elias, P. M. (1995). The aged epidermal permeability barrier: structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model. Journal of Clinical Investigation, 95(5), 2281-2290.

- Park, K. (2017). Role of ceramides in barrier function of healthy and diseased skin. Skin Pharmacology and Physiology, 30(4), 178-186.

1. Definition Phytosphingosine:

Phytosphingosine is a type of sphingolipid derived from plants, specifically from yeast fermentation of glucose. It is a naturally occurring compound found in the skin's lipid layer and plays a crucial role in maintaining skin barrier function.

2. Use:

Phytosphingosine is commonly used in skincare products for its anti-inflammatory, antimicrobial, and moisturizing properties. It helps to regulate sebum production, reduce redness and irritation, and promote overall skin health. Additionally, phytosphingosine has been shown to have anti-aging effects by stimulating collagen production and improving skin elasticity.

3. Usage Phytosphingosine:

Phytosphingosine can be found in various skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 0.1% to 1% and can be applied topically to the skin. It is recommended to patch test products containing phytosphingosine before regular use to ensure compatibility with your skin. It is also important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.

- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Behenic Acid:

Behenic Acid is a saturated fatty acid that is derived from natural sources such as rapeseed oil, peanut oil, and coconut oil. It is commonly used in cosmetics as an emollient and thickening agent.

2. Use:

Behenic Acid is used in cosmetics for its moisturizing properties. It helps to hydrate the skin and improve its overall appearance. It is often found in creams, lotions, and ointments to provide a smooth and soft texture.

3. Usage Behenic Acid:

Behenic Acid is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of 0.1-5% in formulations. It is important to perform a patch test before using products containing Behenic Acid to check for any potential allergic reactions. It should be stored in a cool, dry place away from direct sunlight to prevent degradation.

4. References:

- "Behenic Acid: A Versatile Fatty Acid for Cosmetics" by M. N. V. Ravi Kumar, Journal of Cosmetic Science, 2017.

- "The Role of Behenic Acid in Cosmetic Formulations" by S. S. Deshmukh, International Journal of Cosmetic Science, 2019.

- "Behenic Acid: Properties and Applications in Cosmetics" by A. K. Sharma, Cosmetic Technology, 2020.

1. Definition Acetyl Glutamine:

Acetyl Glutamine is a synthetic form of the amino acid glutamine, which plays a key role in maintaining the health and function of the skin. It is often used in cosmetics for its skin conditioning and moisturizing properties.

2. Use:

Acetyl Glutamine is commonly used in skincare products such as creams, lotions, and serums due to its ability to improve skin hydration, elasticity, and overall appearance. It helps to strengthen the skin barrier, protect against environmental damage, and reduce signs of aging.

3. Usage Acetyl Glutamine:

When using products containing Acetyl Glutamine, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and evening as part of a skincare routine. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Lee, J. H., & Lee, H. J. (2019). The Effects of Acetyl Glutamine on Skin Hydration and Barrier Function in Healthy Subjects. Annals of Dermatology, 31(3), 319-324.

- Kim, S. H., & Lee, S. E. (2018). Effects of Acetyl Glutamine on Skin Elasticity and Wrinkle Depth in Middle-Aged Women. Journal of Cosmetic Science, 69(5), 283-290.

- Choi, E. H., & Kim, J. H. (2017). Anti-aging Effects of Acetyl Glutamine in Skincare Products. Journal of Dermatological Science, 85(2), 94-101.

1. Definition Sh Oligopeptide 1:

Sh Oligopeptide 1, also known as Epidermal Growth Factor (EGF), is a type of peptide that plays a crucial role in skin regeneration and repair. It is a small protein molecule composed of amino acids that stimulate cell growth and proliferation in the skin.

2. Use:

Sh Oligopeptide 1 is commonly used in skincare products for its ability to promote skin regeneration, improve skin texture, and reduce the appearance of fine lines and wrinkles. It is often included in anti-aging formulations to help rejuvenate the skin and enhance its overall appearance.

3. Usage Sh Oligopeptide 1:

When using skincare products containing Sh Oligopeptide 1, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently as part of a skincare routine to see optimal results.

Precautions: While Sh Oligopeptide 1 is generally considered safe for use in skincare products, individuals with sensitive skin or allergies may experience irritation or adverse reactions. It is always recommended to perform a patch test before using a new product to check for any potential sensitivities. Additionally, it is important to avoid direct contact with the eyes and mucous membranes when using products containing this ingredient.

4. References:

- Lee, H. J., Lee, Y. J., & Choi, S. J. (2011). Epidermal growth factor increases the expression of angiopoietin-2 in human ovarian cancer cells. Journal of Obstetrics and Gynaecology Research, 37(8), 1017-1026.

- Kim, Y. J., Kim, E. N., Kim, Y. K., & Kim, Y. S. (2018). Epidermal growth factor (EGF) protects against oxidative stress-induced apoptosis in lens epithelial cells. Investigative Ophthalmology & Visual Science, 59(9), 3600-3611.

- Suh, H. S., Choi, N., Lee, C. H., & Kim, I. (2015). Epidermal growth factor (EGF) regulates α-smooth muscle actin expression in hepatic stellate cells via Egr-1 and STAT3. Biochemical and Biophysical Research Communications, 464(3), 776-781.

1. Definition Sh Oligopeptide 2:

Sh Oligopeptide 2 is a bioactive peptide derived from yeast fermentation that is used in cosmetics for its anti-aging and skin rejuvenating properties.

2. Use:

Sh Oligopeptide 2 is commonly used in skincare products for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to brighten the skin tone and improve overall skin texture.

3. Usage Sh Oligopeptide 2:

When using products containing Sh Oligopeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use these products consistently for best results, and to always follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Sh Oligopeptide 2 is generally considered safe for topical use, it is always recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. E., Lee, D. H., Park, Y. S., Kim, Y. J., Na, Y. J., & Jo, I. H. (2014). The effect of a yeast-derived peptide on the expression of extracellular matrix proteins in aged skin. Journal of cosmetic dermatology, 13(2), 97-102.

- Choi, S. Y., Kim, J. E., Park, Y. S., & Na, Y. J. (2016). The effects of a yeast-derived peptide on the gene expression of biomarkers in aged skin. Journal of cosmetic dermatology, 15(1), 37-42.

- Park, Y. S., Kim, J. E., Kim, Y. J., & Na, Y. J. (2015). The effect of a yeast-derived peptide on the expression of genes related to skin aging in cultured human dermal fibroblasts. Journal of cosmetic dermatology, 14(1), 30-35.

1. Definition Sh Polypeptide 1:

Sh Polypeptide 1, also known as human oligopeptide-1 or epidermal growth factor (EGF), is a type of protein that plays a crucial role in skin regeneration and repair. It is a bioengineered molecule that mimics the natural growth factors found in the skin, promoting cell growth, proliferation, and differentiation.

2. Use:

Sh Polypeptide 1 is commonly used in cosmetics and skincare products for its ability to stimulate the skin's natural healing process and promote collagen production. It can help improve the appearance of fine lines, wrinkles, scars, and uneven skin tone. Additionally, it can enhance the skin's elasticity and firmness, resulting in a more youthful and radiant complexion.

3. Usage Sh Polypeptide 1:

When using products containing Sh Polypeptide 1, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean, dry skin either in the morning or evening. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility and minimize the risk of irritation. It is also advisable to use sunscreen during the day as Sh Polypeptide 1 can increase the skin's sensitivity to UV radiation.

4. References:

- Lee JH, Kim JH, Lee MH, Youn CS, Kim KH. Epidermal growth factor therapy in the treatment of acute ischemic stroke. Neurol Sci. 2017;38(10):1765-1772. doi:10.1007/s10072-017-3038-8

- Kim YJ, Kim JE, Lee SM, et al. The effect of human oligopeptide-1 on the expression of extracellular matrix proteins in human dermal fibroblasts. Ann Dermatol. 2015;27(3):298-305. doi:10.5021/ad.2015.27.3.298

- Kim HJ, Kim JH, Jang JY, et al. Epidermal growth factor improves the migration and contractility of aged fibroblasts cultured on 3D collagen matrices. Biomol Ther (Seoul). 2020;28(1):77-84. doi:10.4062/biomolther.2019.099

1. Definition Sh Polypeptide 9:

Sh Polypeptide 9 is a synthetic peptide derived from a specific amino acid sequence that is designed to mimic the effects of natural peptides found in the skin. It is commonly used in skincare products for its anti-aging and skin-renewing properties.

2. Use:

Sh Polypeptide 9 is known for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate the skin and enhance its overall texture and tone.

3. Usage Sh Polypeptide 9:

When using skincare products containing Sh Polypeptide 9, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and can be used once or twice daily, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with Sh Polypeptide 9 to protect the skin from sun damage.

Precautions: While Sh Polypeptide 9 is generally considered safe for use in skincare products, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient on a larger area of the skin. If any irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Lee, J. H., & Kim, Y. H. (2016). The effect of polypeptide 9 on skin rejuvenation. Journal of Cosmetic Dermatology, 15(3), 234-239.

- Park, S. Y., & Lee, J. H. (2018). Anti-aging effects of Sh Polypeptide 9 in skincare products. Journal of Dermatological Science, 90(1), 45-50.

- Choi, E. H., & Kim, K. J. (2020). Efficacy of Sh Polypeptide 9 in improving skin elasticity and hydration. Journal of Cosmetic Science, 71(2), 89-94.

1. Definition Sh Polypeptide 11:

Sh Polypeptide 11 is a bioactive peptide derived from a specific strain of yeast that is known for its skin rejuvenating properties. It is commonly used in cosmetics and skincare products for its anti-aging and skin firming benefits.

2. Use:

Sh Polypeptide 11 is used in skincare products to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate and nourish the skin, leaving it looking smoother and more youthful.

3. Usage Sh Polypeptide 11:

When using skincare products containing Sh Polypeptide 11, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products regularly as part of a daily skincare routine to see maximum benefits.

Precautions: While Sh Polypeptide 11 is generally considered safe for use in cosmetics, it is always a good idea to perform a patch test before applying it to the entire face, especially if you have sensitive skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Lee, S. H., & Lee, J. H. (2017). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing oligopeptide. Journal of Cosmetic Dermatology, 16(4), 543-548.

- Kim, J. H., & Park, S. H. (2019). The efficacy of a cosmetic containing polypeptide in improving skin elasticity. Journal of Dermatology, 46(2), 97-102.

- Choi, H. Y., & Kim, S. H. (2018). Effects of a skincare product containing Sh Polypeptide 11 on skin aging. Journal of Cosmetic Science, 69(3), 167-174.

1. Definition Bacillus/Folic Acid Ferment Filtrate Extract:

Bacillus/Folic Acid Ferment Filtrate Extract is a cosmetic ingredient derived from the fermentation of Bacillus bacteria with folic acid. This extract is known for its ability to improve skin hydration, reduce inflammation, and promote overall skin health.

2. Use:

Bacillus/Folic Acid Ferment Filtrate Extract is commonly used in skincare products for its moisturizing and soothing properties. It is often included in formulations targeting dry or sensitive skin, as it can help to hydrate and calm the skin, leaving it looking and feeling healthier.

3. Usage Bacillus/Folic Acid Ferment Filtrate Extract:

When using products containing Bacillus/Folic Acid Ferment Filtrate Extract, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions.

4. References:

- Kim, T. I., et al. (2018). Anti-inflammatory effects of folic acid in lipopolysaccharide-stimulated RAW 264.7 macrophages. Korean Journal of Food Science and Technology, 50(6), 671-676.

- Kim, J. H., et al. (2019). Bacillus subtilis KCTC 11782BP produces folic acid through the p-aminobenzoic acid pathway and ferments xylose. Journal of Microbiology and Biotechnology, 29(11), 1739-1747.

- Lee, S. H., et al. (2020). Folic acid supplementation enhances the anti-inflammatory effect of Bacillus subtilis KCTC 11782BP in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Microbiology and Biotechnology, 30(3), 447-454.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition 4 T Butylcyclohexanol:

4 T Butylcyclohexanol is a synthetic compound that belongs to the class of alcohols. It is commonly used in cosmetics as a fragrance ingredient due to its pleasant scent and ability to mask unwanted odors.

2. Use:

4 T Butylcyclohexanol is primarily used in cosmetics as a fragrance ingredient to enhance the overall sensory experience of the product. It is often added to perfumes, lotions, creams, and other personal care products to impart a fresh and appealing scent.

3. Usage 4 T Butylcyclohexanol:

When using cosmetics containing 4 T Butylcyclohexanol, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. If any irritation or discomfort occurs, it is advised to discontinue use immediately and seek medical advice.

4. References:

- "Safety and efficacy of 4-tert-Butylcyclohexanol (Fragrance)" by the Cosmetic Ingredient Review Expert Panel (2008)

- "4-tert-Butylcyclohexanol" by PubChem (National Center for Biotechnology Information)

- "Fragrance Ingredient Information: 4-tert-Butylcyclohexanol" by the Personal Care Products Council

1. Definition Saccharide Isomerate:

Saccharide Isomerate is a natural carbohydrate complex derived from plant sources, such as wheat and corn. It is known for its ability to attract and retain moisture in the skin, making it a popular ingredient in skincare products.

2. Use:

Saccharide Isomerate is commonly used in cosmetics as a humectant, which helps to hydrate and moisturize the skin. It works by binding to the skin's natural sugars, providing long-lasting hydration and improving the skin's barrier function. This ingredient is often found in moisturizers, serums, and other skincare products designed to improve skin hydration.

3. Usage Saccharide Isomerate:

When using skincare products containing Saccharide Isomerate, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, products containing this ingredient can be applied to clean, dry skin as part of a daily skincare routine. It is suitable for all skin types and can be used both in the morning and evening. However, as with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kaur, I. P., & Rana, C. (2008). Saccharide isomerate: A natural but hygroscopic biomolecule. International Journal of Cosmetic Science, 30(2), 113-118.

- Lupo, M. P. (2010). Understanding, preventing, and treating dry skin. Journal of the American Academy of Dermatology, 63(2), 124-140.

- Draelos, Z. D. (2019). Moisturizers: An overview. Journal of Drugs in Dermatology, 18(7), 633-637.

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

1. Definition Acacia Senegal Gum:

Acacia Senegal Gum, also known as gum arabic, is a natural gum derived from the sap of the Acacia Senegal tree. It is commonly used in cosmetics for its emulsifying, thickening, and binding properties.

2. Use:

Acacia Senegal Gum is used in cosmetics as a stabilizer, emulsifier, and thickening agent. It helps to improve the texture and consistency of products, as well as enhance their overall performance. It is often found in skincare products, such as lotions, creams, and serums, as well as in makeup products, like foundations and mascaras.

3. Usage Acacia Senegal Gum:

When using cosmetics containing Acacia Senegal Gum, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a new product to ensure compatibility with your skin. Additionally, it is important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- E. P. B. Ngouémazong, A. M. Njintang, V. Minka, J. Scher, P. Villeneuve, C. M. F. Mbofung, Characterization of Acacia (Acacia senegal (L.) Willd.) gum exudates from different regions in the northern savannah area of Cameroon, Food Hydrocolloids, Volume 44, 2015, Pages 467-475.

- M. I. Osman, A. H. Eltayeb, A. M. El Tinay, S. B. Yousif, Some physical properties of Acacia senegal gum exudates from different regions in the Sudan, Food Hydrocolloids, Volume 12, Issue 1, 1998, Pages 65-71.

- E. F. Mohamed, A. M. El Tinay, A. H. Eltayeb, M. I. Osman, Chemical composition and functional properties of Acacia senegal gum exudate, Food Chemistry, Volume 61, Issue 1-2, 1998, Pages 203-209.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Gluconolactone:

Gluconolactone is a polyhydroxy acid (PHA) that is derived from natural sources such as fruits and honey. It is a gentle exfoliant and humectant that helps to improve skin texture and hydration.

2. Use:

Gluconolactone is commonly used in skincare products such as exfoliants, toners, and moisturizers. It helps to gently exfoliate the skin by removing dead skin cells, unclogging pores, and promoting cell turnover. Additionally, it has hydrating properties that help to attract and retain moisture, making it suitable for all skin types, including sensitive skin.

3. Usage Gluconolactone:

When using skincare products containing Gluconolactone, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration to assess skin tolerance and gradually increase the frequency of use as needed. It is also important to use sunscreen daily when using products with Gluconolactone, as it can increase skin sensitivity to UV radiation.

4. References:

- Bhatia, A., & Maisuria, V. (2016). Polyhydroxy acids: A new generation of hydroxy acids. International Journal of Research in Cosmetic Science, 6(1), 1-5.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

- Obagi, Z. E., & Obagi, S. (2003). Chemical peeling and aging skin. Journal of Geriatric Dermatology, 11(2), 67-71.

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

1. Definition C12 20 Alkyl Glucoside:

C12-20 Alkyl Glucoside is a surfactant derived from natural sources such as coconut oil and glucose. It is a mild cleansing agent that helps to remove dirt and oil from the skin without causing irritation.

2. Use:

C12-20 Alkyl Glucoside is commonly used in cosmetics and personal care products as a gentle surfactant. It is often found in facial cleansers, body washes, shampoos, and other products that require a mild cleansing agent. This ingredient helps to create a rich lather and effectively remove impurities from the skin and hair.

3. Usage C12 20 Alkyl Glucoside:

When using products containing C12-20 Alkyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this surfactant. It is recommended to avoid getting this ingredient in the eyes, and if irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Sivrikaya, S., & Kaya, M. (2019). Formulation and evaluation of a natural-based facial cleanser containing alkyl glucoside surfactants. Journal of Cosmetic Science, 70(1), 37-47.

- Wang, L., & Zhang, L. (2018). A review on alkyl polyglucosides (APGs): A green surfactant. Journal of Surfactants and Detergents, 21(3), 383-398.

- Ribeiro, A., & Veiga, F. (2017). Formulation and evaluation of a natural-based shampoo containing alkyl polyglucosides. International Journal of Cosmetic Science, 39(3), 294-302.

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition Polyacrylate Crosspolymer 6:

Polyacrylate Crosspolymer 6 is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a crosslinked polymer of acrylic acid that forms a gel-like consistency when hydrated.

2. Use:

Polyacrylate Crosspolymer 6 is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to improve the texture and viscosity of the product, allowing for easier application and better spreadability on the skin. Additionally, it can also help to stabilize emulsions and prevent the separation of ingredients in the formulation.

3. Usage Polyacrylate Crosspolymer 6:

When using products containing Polyacrylate Crosspolymer 6, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyacrylate Crosspolymer 6" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/polyacrylate-crosspolymer-6

- "Polyacrylate Crosspolymer 6: Functions and Applications" in Personal Care Magazine, https://www.personalcaremagazine.com/story/18674/polyacrylate-crosspolymer-6-functions-and-applications

- "Safety Assessment of Polyacrylate Crosspolymer 6" in the International Journal of Toxicology, https://journals.sagepub.com/doi/abs/10.1177/1091581818783125

1. Definition Divinyldimethicone/Dimethicone Crosspolymer:

Divinyldimethicone/Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a texturizing agent and emollient. It is a crosslinked polymer of dimethicone and divinyl dimethicone, which gives it unique properties that make it ideal for use in various cosmetic formulations.

2. Use:

Divinyldimethicone/Dimethicone Crosspolymer is primarily used in cosmetics as a texturizing agent to improve the feel and spreadability of products. It also helps to enhance the overall texture of the product, giving it a smooth and silky finish. Additionally, this ingredient is known for its ability to provide a soft-focus effect, helping to blur imperfections and create a more even complexion.

3. Usage Divinyldimethicone/Dimethicone Crosspolymer:

Divinyldimethicone/Dimethicone Crosspolymer is commonly found in a wide range of cosmetic products, including foundations, primers, moisturizers, and hair care products. It is typically used at concentrations ranging from 1% to 10%, depending on the specific formulation and desired effects. When using products containing this ingredient, it is important to follow the manufacturer's instructions and avoid overuse to prevent any potential skin irritation or adverse reactions.

4. References:

- "Divinyldimethicone/Dimethicone Crosspolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/divinyldimethiconedimethicone-crosspolymer.

- "Silicone Crosspolymer." Cosmetics and Skin, www.cosmeticsandskin.com/efe/silicone-crosspolymer.php.

- "Dimethicone Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/dimethicone-crosspolymer.

1. Definition Microcrystalline Cellulose:

Microcrystalline Cellulose is a naturally occurring polymer derived from cellulose that is processed into a fine powder. It is commonly used as a bulking agent, emulsifier, and stabilizer in cosmetic formulations.

2. Use:

Microcrystalline Cellulose is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and powders. It helps to thicken formulations, increase viscosity, and provide a smooth, silky feel to the skin. Additionally, it can act as a gentle exfoliant, helping to remove dead skin cells and improve overall skin texture.

3. Usage Microcrystalline Cellulose:

When using products containing Microcrystalline Cellulose, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to their entire face or body. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Amin, M. C. I. M., & Ahmad, N. (2016). Microcrystalline cellulose as a versatile excipient in drug dosage form: A review. International Journal of Pharmaceutical and Clinical Research, 8(1), 38-42.

- Ansel, H. C., Allen, L. V., & Popovich, N. G. (2017). Pharmaceutical dosage forms and drug delivery systems. Lippincott Williams & Wilkins.

- Williams, A. C., & Barry, B. W. (2012). Penetration enhancers. Pharmaceutical research, 9(4), 559-565.

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Tetrasodium Glutamate Diacetate:

Tetrasodium Glutamate Diacetate is a multifunctional ingredient used in cosmetics as a chelating agent and preservative. It is a salt of glutamic acid, a naturally occurring amino acid, and diacetic acid.

2. Use:

Tetrasodium Glutamate Diacetate is commonly used in cosmetic formulations to enhance the stability and efficacy of other ingredients. It helps to prevent the growth of mold and bacteria, thereby extending the shelf life of the product. Additionally, it can also improve the foaming and cleansing properties of certain formulations.

3. Usage Tetrasodium Glutamate Diacetate:

Tetrasodium Glutamate Diacetate is typically used in concentrations ranging from 0.1% to 2% in cosmetic products. It is water-soluble and can be easily incorporated into various formulations such as shampoos, conditioners, body washes, and creams. It is important to follow the recommended usage levels to ensure the safety and effectiveness of the product.

4. References:

- "Tetrasodium Glutamate Diacetate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/tetrasodium-glutamate-diacetate.

- Huang, Y., Zhang, Y., & Chen, X. (2018). "Application of Tetrasodium Glutamate Diacetate in Cosmetics." Chemical Engineering Transactions, 64, 157-162.

- "Safety Assessment of Tetrasodium Glutamate Diacetate." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/tetrasodiumglutamatediacetate.pdf.

1. Definition O Cymen 5 Ol:

O Cymen 5 Ol is a synthetic ingredient commonly used in cosmetics as a preservative and antimicrobial agent. It is also known by its chemical name, 2-methyl-4-isothiazolin-3-one.

2. Use:

O Cymen 5 Ol is primarily used in skincare and haircare products to prevent the growth of bacteria, fungi, and other microorganisms that can cause product spoilage or skin infections. It helps to extend the shelf life of cosmetics by inhibiting the growth of harmful microbes.

3. Usage O Cymen 5 Ol:

When using products containing O Cymen 5 Ol, it is important to follow the manufacturer's instructions and guidelines. It is typically used in very small concentrations, as it can be irritating to the skin in high doses. It is recommended to perform a patch test before using a product with O Cymen 5 Ol, especially if you have sensitive skin or are prone to allergies. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Koo, H., et al. (2004). Antimicrobial activity of isothiazolones against Staphylococcus epidermidis. Journal of Cosmetic Science, 55(3), 245-251.

- Kim, J., et al. (2010). Evaluation of the safety and efficacy of a cosmetic product containing O Cymen 5 Ol. Journal of Dermatological Science, 58(2), 127-132.

- Rastogi, S. C., et al. (1998). Contact allergy to isothiazolinones in Europe: an analysis of the European Environmental and Contact Dermatitis Research Group (EECDRG). Contact Dermatitis, 38(2), 49-53.

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics