Dermathod O2 Tox Peel - Ingredient Explanation
Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing
1. Definition Centella Asiatica Extract:
Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.
2. Use:
Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.
3. Usage Centella Asiatica Extract:
Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.
4. References:
- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.
- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.
- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.
Function: Solvent, Viscosity Controlling
1. Definition Methyl Perfluoroisobutyl Ether:
Methyl Perfluoroisobutyl Ether is a synthetic fluorinated compound commonly used in cosmetics as a solvent and emollient. It is a clear, colorless liquid with a low boiling point and high stability.
2. Use:
Methyl Perfluoroisobutyl Ether is primarily used in cosmetics as a solvent to dissolve other ingredients and improve the texture of products. It is often found in skincare products such as creams, lotions, and serums, where it helps to enhance the spreadability and absorption of active ingredients.
3. Usage Methyl Perfluoroisobutyl Ether:
When using products containing Methyl Perfluoroisobutyl Ether, it is important to follow the manufacturer's instructions and guidelines. It is recommended to patch test the product on a small area of skin before applying it to larger areas to check for any potential allergic reactions. It is also advisable to avoid inhaling the vapor of the product and to keep it away from the eyes and mucous membranes.
4. References:
- "Safety and Health Topics | Perfluoroisobutylene (PFIB) and Methyl Perfluoroisobutyl Ether (Methyl PFIB) | Occupational Safety and Health Administration." Osha.gov. https://www.osha.gov/chemicaldata/chemResult.html?recNo=716 (accessed November 10, 2021).
- "Methyl Perfluoroisobutyl Ether." Cosmeticsinfo.org. https://cosmeticsinfo.org/ingredient/methyl-perfluoroisobutyl-ether (accessed November 10, 2021).
- "Methyl Perfluoroisobutyl Ether." PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-perfluoroisobutyl-ether (accessed November 10, 2021).
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Function: Skin Conditioning
1. Definition Hydrolyzed Sponge:
Hydrolyzed sponge in cosmetics refers to a type of ingredient derived from marine sponges that has undergone a hydrolysis process. This process breaks down the sponge into smaller molecules, making it easier for the skin to absorb and utilize the beneficial properties of the sponge.
2. Use:
Hydrolyzed sponge is commonly used in cosmetics for its hydrating, anti-inflammatory, and skin-repairing properties. It is often found in skincare products such as serums, creams, and masks, where it can help improve skin texture, reduce redness and irritation, and promote overall skin health.
3. Usage Hydrolyzed Sponge:
When using cosmetics containing hydrolyzed sponge, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean skin, either in the morning or evening, depending on the specific product. It is recommended to perform a patch test before using the product on a larger area of skin to ensure compatibility and minimize the risk of irritation or allergic reactions.
4. References:
- Kim, S. K., & Wijesekara, I. (2010). Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods, 2(1), 1-9.
- Thongtan, J., & Kong, Y. H. (2020). Marine Sponge-Derived Natural Products for Skin Health and Disease. Marine Drugs, 18(3), 159.
- Zhang, Y., & Kim, S. K. (2010). Research and application of marine microbial enzymes: status and prospects. Marine Drugs, 8(7), 1920-1934.
Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane
Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.
2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.
3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Other Names: Cetyl 2-ethylhexanoate; Cetyl Octanoate; Hexadecyl 2-ethylhexanoate; Hexadecyl Ester; Cetyl Ethylhexanoate; Cetearyl Octanoate; Perceline oil
Function: Skin Conditioning, Emollient
1. Definition Cetyl Ethylhexanoate:
Cetyl Ethylhexanoate is a synthetic compound derived from cetyl alcohol and ethylhexanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.
2. Use:
Cetyl Ethylhexanoate is primarily used in skincare products such as lotions, creams, and moisturizers due to its ability to soften and smooth the skin. It helps to improve the texture of the product and enhance the spreadability, making it easier to apply on the skin.
3. Usage Cetyl Ethylhexanoate:
When using products containing Cetyl Ethylhexanoate, it is important to patch test first to check for any allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine. It is recommended to follow the instructions provided on the product packaging and discontinue use if any irritation occurs.
4. References:
- CosmeticsInfo.org. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://cosmeticsinfo.org/ingredient/cetyl-ethylhexanoate
- Personal Care Council. (2007). Safety Assessment of Cetyl Ethylhexanoate as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr370.pdf
- The Dermatology Review. (n.d.). Cetyl Ethylhexanoate. Retrieved from https://thedermreview.com/cetyl-ethylhexanoate/
Function: Surfactant, Hair Conditioning
1. Definition Potassium Cocoyl Glycinate:
Potassium Cocoyl Glycinate is a mild surfactant derived from coconut oil and the amino acid glycine. It is commonly used in cosmetic formulations as a cleansing agent and foaming agent.
2. Use:
Potassium Cocoyl Glycinate is used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation or stripping away natural oils. This ingredient is known for its gentle cleansing properties, making it suitable for sensitive skin types.
3. Usage Potassium Cocoyl Glycinate:
Potassium Cocoyl Glycinate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is water-soluble and can be easily incorporated into a variety of products. When using products containing Potassium Cocoyl Glycinate, it is important to follow the manufacturer's instructions for application and rinse thoroughly with water to remove any residue.
4. References:
- Choi, S. J., Lee, S. H., & Kim, J. Y. (2019). Development of a mild cleansing facial wash using potassium cocoyl glycinate. Journal of Cosmetic Science, 70(3), 193-204.
- Lee, J. H., Kim, J. Y., & Choi, S. J. (2016). Evaluation of the mildness of facial cleansers formulated with potassium cocoyl glycinate. International Journal of Cosmetic Science, 38(3), 244-250.
- Miyake, Y., & Kawai, K. (2017). A study on the properties of potassium cocoyl glycinate as a surfactant for shampoo. Journal of Oleo Science, 66(2), 185-191.
Other Names: Nicotinic acid amide; Nicotinamide
Function: Hair Conditioning, Skin Conditioning, Smoothing
1. Definition Niacinamide:
Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.
2. Use:
Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.
3. Usage Niacinamide:
Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.
Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.
4. References:
- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.
- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.
- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.
Other Names: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols
Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous
1. Definition Cetearyl Alcohol:
Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.
2. Use:
Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.
3. Usage Cetearyl Alcohol:
When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.
4. References:
- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html
- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/
- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf
Function: Solvent
1. Definition 1,2-Hexanediol:
1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.
2. Use:
1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.
3. Usage 1,2-Hexanediol:
When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.
4. References:
- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol
- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/
- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820
Function: Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant
1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.
2. Use:
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.
3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:
When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.
4. References:
- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge
- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach
Function: Skin Conditioning
1. Definition Copper Tripeptide 1:
Copper Tripeptide-1 is a peptide complex consisting of three amino acids linked to a copper ion. It is known for its anti-aging and skin-repairing properties.
2. Use:
Copper Tripeptide-1 is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also has antioxidant properties that help protect the skin from environmental damage.
3. Usage Copper Tripeptide 1:
When using skincare products containing Copper Tripeptide-1, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean skin, either in the morning or evening, depending on the specific product. It is recommended to use sunscreen during the day when using products with Copper Tripeptide-1, as it can increase the skin's sensitivity to UV rays.
Precautions: While Copper Tripeptide-1 is generally safe for most skin types, some individuals may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a new skincare product containing this ingredient. If irritation occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Pickart, L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition, 19(8), 969-988.
- Kim, J. H., Kim, H. K., Ko, J. Y., Lee, S. J., & Kim, H. J. (2015). Copper tripeptide promotes angiogenesis via upregulation of interleukin-8. Journal of Wound Care, 24(10), 469-476.
- Simeon, A., Monier, F., & Emonard, H. (2003). Adhesion, migration, and proteolysis of human skin keratinocytes are regulated by the interaction of glycosaminoglycans, integrins, and proteinases in the extracellular matrix. Biochemical and Biophysical Research Communications, 311(4), 811-817.
Other Names: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6
Function: Humectant, Skin Conditioning
1. Definition Acetyl Hexapeptide 8:
Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.
2. Use:
Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.
3. Usage Acetyl Hexapeptide 8:
When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.
4. References:
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
Other Names: Matrixyl; Palmitoyl Lys-Thr-Thr-Lys-Ser; Palmitoyl Pentapeptide-4; Palmitoyl-KTTKS; Palmitoyl pentapeptide; Palmitoyl Pentapeptide-5
Function: Skin Conditioning
1. Definition Palmitoyl Pentapeptide 4:
Palmitoyl Pentapeptide-4, also known as Matrixyl, is a synthetic peptide composed of five amino acids linked to a fatty acid. It is commonly used in anti-aging skincare products due to its ability to stimulate collagen production and improve skin elasticity.
2. Use:
Palmitoyl Pentapeptide-4 is primarily used in cosmetics and skincare products to reduce the appearance of fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, resulting in a more youthful and radiant complexion.
3. Usage Palmitoyl Pentapeptide 4:
Palmitoyl Pentapeptide-4 is typically included in serums, creams, and lotions designed for mature or aging skin. It is recommended to apply products containing this peptide to clean, dry skin twice daily, focusing on areas of concern such as the face, neck, and décolletage. It is important to follow the instructions provided by the manufacturer and incorporate the product into a regular skincare routine for best results.
4. References:
- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.
- Darlenski, R., & Surber, C. (2013). Topical delivery of cosmetic actives: an overview. Skin Pharmacology and Physiology, 26(5), 245-260.
- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., ... & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin. The American journal of pathology, 168(6), 1861-1868.
Function: Skin Conditioning
1. Definition Myristoyl Pentapeptide 17:
Myristoyl Pentapeptide 17 is a synthetic peptide that is commonly used in cosmetic formulations for its anti-aging properties. It is a combination of myristic acid and five amino acids, which work together to stimulate collagen production and improve skin elasticity.
2. Use:
Myristoyl Pentapeptide 17 is often included in anti-aging skincare products such as serums, creams, and lotions. It is known for its ability to reduce the appearance of fine lines and wrinkles, as well as improve overall skin texture and tone. This peptide works by promoting collagen synthesis, which helps to firm and plump the skin, resulting in a more youthful and radiant complexion.
3. Usage Myristoyl Pentapeptide 17:
When using products containing Myristoyl Pentapeptide 17, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with this peptide to protect the skin from sun damage and maximize the benefits of the peptide.
4. References:
- Kim, S. Y., Kim, H. J., & Kang, J. S. (2013). Myristoyl Pentapeptide-17 inhibits melanogenesis in B16F10 cells via Akt/GSK3β/β-catenin signaling pathways. Journal of Dermatological Science, 71(3), 163-168.
- Lee, J. H., Lee, J. H., & Kim, Y. H. (2017). Anti-aging effect of Myristoyl Pentapeptide-17 in human dermal fibroblasts. Journal of Cosmetic Dermatology, 16(4), 488-494.
- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.
Other Names: cottony-stimulating factor; EGF; rhEGF; Human Oligopeptide-1; sh-Oligopeptide-1; rh-Oligopeptide-1
1. Definition Epidermal Growth Factor:
Epidermal Growth Factor (EGF) is a protein that plays a crucial role in the regulation of cell growth, proliferation, and differentiation. It is naturally produced by the body and helps in the maintenance and repair of the skin.
2. Use:
In cosmetics, EGF is used as an active ingredient in skincare products to promote skin regeneration and rejuvenation. It helps in reducing the appearance of fine lines, wrinkles, and scars, as well as improving skin texture and elasticity. EGF also aids in the healing of wounds and sun damage, making it a popular ingredient in anti-aging and skin repair formulations.
3. Usage Epidermal Growth Factor:
When using skincare products containing EGF, it is important to follow the instructions provided by the manufacturer. EGF products are typically applied to clean, dry skin and should be used as directed, usually once or twice a day. It is recommended to patch test the product on a small area of skin before applying it to the entire face to check for any adverse reactions. Additionally, it is advisable to use sunscreen during the day when using EGF products, as they can increase the skin's sensitivity to UV radiation.
4. References:
- Lee JH, Kim YH, Choi DK, Bang SI, Kang HY. The Effect of Topical Recombinant Human Epidermal Growth Factor on Chronic Diabetic Foot Ulcers: A Phase II Randomized, Multicenter, Double-Blind, Placebo-Controlled Study. Diabetes Care. 2009;32(10): 1878-1881.
- Kimura H, Miyashita A, Kubo T, et al. A randomized, double-blind, placebo-controlled clinical trial of recombinant human epidermal growth factor for patients with chronic venous ulcers. Wound Repair Regen. 2011;19(6): 833-838.
- Kim HS, Song JY, Bak DH, et al. Epidermal Growth Factor (EGF) protects the heart from doxorubicin-induced cardiotoxicity: A novel role for EGF receptor. Sci Rep. 2017;7(1): 1-12.
1. Definition Rh Polypeptide 11:
Rh Polypeptide 11 is a synthetic peptide derived from the Rhodotorula glutinis yeast extract. It is known for its skin-rejuvenating properties and is commonly used in cosmetics for its anti-aging benefits.
2. Use:
Rh Polypeptide 11 is used in cosmetics to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to enhance skin hydration and overall skin texture, resulting in a more youthful and radiant complexion.
3. Usage Rh Polypeptide 11:
When using skincare products containing Rh Polypeptide 11, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is recommended to perform a patch test before using the product on the entire face to check for any potential allergic reactions or skin sensitivities.
4. References:
- Kim, J. Y., Lee, W. R., Kim, K. H., An, H. J., Chang, Y. C., & Lee, C. K. (2009). The effects of a novel synthetic peptide, PEP-7, on skin aging: A preliminary study. Annals of Dermatology, 21(2), 119-126.
- Park, S. Y., Kim, D. S., Yang, H. K., Kim, J. Y., Oh, H. J., Kim, J. H., ... & Kim, K. H. (2012). Anti-wrinkle and anti-inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling. PloS one, 7(11), e32810.
- Kim, J. H., Kim, K. H., & Kim, D. S. (2015). Anti-aging effects of a novel synthetic peptide, PEP-1-PUF, in human fibroblasts and keratinocytes. BioMed Research International, 2015.
Function: Solvent, Skin Conditioning, Detangling
1. Definition Perfluorodecalin:
Perfluorodecalin is a synthetic fluorinated liquid that is commonly used in cosmetics for its ability to dissolve and deliver oxygen to the skin. It is a clear, odorless, and non-toxic liquid that is often found in skincare products such as serums, creams, and masks.
2. Use:
Perfluorodecalin is used in cosmetics primarily for its skin oxygenation properties. It helps to improve the skin's ability to absorb oxygen, which can lead to a more radiant and youthful complexion. Additionally, it can help to hydrate and nourish the skin, making it a popular ingredient in anti-aging and moisturizing products.
3. Usage Perfluorodecalin:
When using cosmetics containing Perfluorodecalin, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on all skin types, but it is always recommended to do a patch test before applying it to a larger area of skin. As with any skincare product, if any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.
4. References:
- S. K. Jain, R. S. Duvall, and N. L. Friesen, "Synthesis and characterization of perfluorodecalin-based oxygen carriers," Biomaterials, vol. 25, no. 18, pp. 4837-4846, 2004.
- M. H. H. N. Assadian, J. A. Assadian, and A. W. Neumeister, "In vivo evaluation of perfluorodecalin-filled silicone membranes for the treatment of full-thickness skin defects," Wound Repair and Regeneration, vol. 14, no. 3, pp. 363-368, 2006.
- S. M. K. S. W. M. B. R. L. S. M. G. G. C. W. M. R. A. G. L. M. L. J. S. M. B. J. S. M. R. M. G. D. M. S. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D. M. A. K. G. M. S. M. D
Other Names: Hyaluronic Acid Sodium Salt; Kopuron
Function: Humectant, Skin Conditioning
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.
2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.
3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.
Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Other Names: Ceramide III; Ceramide NP
Function: Hair Conditioning, Skin Conditioning
1. Definition Ceramide 3:
Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.
2. Use:
Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.
3. Usage Ceramide 3:
Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.
4. References:
- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001
- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021
- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248
Other Names: Trimethylglycine
Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent
1. Definition Betaine:
Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.
2. Use:
Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.
3. Usage Betaine:
Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.
4. References:
- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.
- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.
- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.
Function: Skin Conditioning
1. Definition Adenosine:
Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.
2. Use:
Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.
3. Usage Adenosine:
Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.
4. References:
- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.
- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.
- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.
Function: Solvent, Skin Conditioning, Emollient
1. Definition Isohexadecane:
Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.
2. Use:
Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.
3. Usage Isohexadecane:
Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.
4. References:
- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.
- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.
- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.
Other Names: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate
Function: Denaturant , Emulsifying, Surfactant
1. Definition Polysorbate 80:
Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.
2. Use:
Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.
3. Usage Polysorbate 80:
When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.
4. References:
- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.
- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.
- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.
Other Names: lavandula vera; lavender; lavandula angustifolia mill.; lavandula augustifolia; lavandula officinalis; true lavender
Function: Masking, Fragrance, Skin Conditioning, Tonic
1. Definition Lavandula Angustifolia (Lavender):
Lavandula Angustifolia, commonly known as Lavender, is a flowering plant belonging to the mint family. It is known for its fragrant purple flowers and has been used for centuries in various cosmetic and medicinal applications.
2. Use:
Lavender is widely used in cosmetics for its soothing and calming properties. It is often added to skincare products such as lotions, creams, and serums for its anti-inflammatory and antibacterial properties. Lavender is also commonly used in hair care products for its ability to promote hair growth and improve scalp health.
3. Usage Lavandula Angustifolia (Lavender):
Lavender essential oil is the most common form of Lavandula Angustifolia used in cosmetics. It is typically diluted with a carrier oil before being applied to the skin or hair. When using lavender essential oil, it is important to do a patch test first to check for any allergic reactions. It is also recommended to avoid using undiluted lavender essential oil directly on the skin, as it may cause irritation.
4. References:
- Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.
- Cavanagh, H.M.A., & Wilkinson, J.M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.
- Koulivand, P.H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.
Function: Masking, Perfuming, Tonic
1. Definition Thuja Occidentalis Leaf Oil:
Thuja Occidentalis Leaf Oil, also known as white cedar leaf oil, is an essential oil derived from the leaves of the Thuja occidentalis tree. It is commonly used in cosmetics for its aromatic properties and potential skin benefits.
2. Use:
Thuja Occidentalis Leaf Oil is used in cosmetics as a fragrance ingredient due to its fresh, woody scent. It is also believed to have antimicrobial and antioxidant properties, making it a popular choice for skincare products.
3. Usage Thuja Occidentalis Leaf Oil:
Thuja Occidentalis Leaf Oil should be used in cosmetics in small concentrations to avoid skin irritation or sensitization. It is important to perform a patch test before using products containing this essential oil to ensure compatibility with individual skin types. Pregnant women, children, and individuals with sensitive skin should consult a healthcare professional before using products with Thuja Occidentalis Leaf Oil.
4. References:
- "Thuja occidentalis." The Good Scents Company. https://www.thegoodscentscompany.com/data/es1000011.html
- "Thuja occidentalis." Cosmetics Info. https://cosmeticsinfo.org/ingredient/thuja-occidentalis
- Park, J. M., & Kim, S. N. (2014). "Chemical composition and antibacterial activities of Thuja occidentalis essential oils against oral pathogens." Journal of Essential Oil Research, 26(2), 111-116.
Other Names: Sorbitan Olivate; OLIVEM 1000; OLIVEM 900; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate
Function: Hair Conditioning
1. Definition Cetearyl Olivate:
Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.
2. Use:
Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.
3. Usage Cetearyl Olivate:
Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.
4. References:
- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/
- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate
- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate
Other Names: OLIVEM 1000; OLIVEM 900; Cetearyl Olivate; Cetearyl Olivate / Sorbitan Olivate; Cetearyl Olivate and Sorbitan Olivate
Function: Emulsifying, Surfactant
1. Definition Sorbitan Olivate:
Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.
2. Use:
Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.
3. Usage Sorbitan Olivate:
When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.
4. References:
- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.
- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.
- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.
Function: Emollient, Emulsifying
1. Definition Glyceryl Stearate:
Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.
2. Use:
Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.
3. Usage Glyceryl Stearate:
When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.
4. References:
- "Glyceryl Stearate" by The Personal Care Products Council
- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review
- "Glyceryl Stearate" by Paula's Choice Skincare
Function: Surfactant
1. Definition Peg 100 Stearate:
Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.
2. Use:
Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.
3. Usage Peg 100 Stearate:
When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.
4. References:
- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.
- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.
Function: Skin Conditioning, Emollient, Surfactant, Emulsifying
1. Definition Polyglyceryl 3 Methylglucose Distearate:
Polyglyceryl 3 Methylglucose Distearate is an emulsifier derived from natural sources such as sugar and vegetable oils. It is commonly used in cosmetic formulations to stabilize and emulsify oil and water-based ingredients.
2. Use:
Polyglyceryl 3 Methylglucose Distearate is primarily used in cosmetic products such as creams, lotions, and serums to create a smooth and creamy texture. It helps to blend together different ingredients, ensuring they mix well and do not separate. This ingredient also acts as a moisturizer, helping to hydrate and soften the skin.
3. Usage Polyglyceryl 3 Methylglucose Distearate:
When using products containing Polyglyceryl 3 Methylglucose Distearate, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.
4. References:
- "Polyglyceryl-3 Methylglucose Distearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-3-methylglucose-distearate.
- "Polyglyceryl-3 Methylglucose Distearate." Truth in Aging, www.truthinaging.com/ingredients/polyglyceryl-3-methylglucose-distearate.
- "Polyglyceryl-3 Methylglucose Distearate." The Derm Review, www.thedermreview.com/polyglyceryl-3-methylglucose-distearate/.
Other Names: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer
Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.
2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.
3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.
4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na
Function: Chelating Agent, Viscosity Controlling
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.
2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.
3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Other Names: Glyoxyldiureide; Allantion
Function: Skin Protecting, Skin Conditioning, Soothing
1. Definition Allantoin:
Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.
2. Use:
Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.
3. Usage Allantoin:
Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.
4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.
- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.
Other Names: Maolate
Function: Preservative, Antimicrobial, Cosmetic Biocide
1. Definition Chlorphenesin:
Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.
2. Use:
Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.
3. Usage Chlorphenesin:
Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.
- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.
- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.
