DermDoc 5% Glycolic Acid Underarm Treatment

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Saccharum Officinarum (Sugar Cane) Extract:

Saccharum Officinarum (Sugar Cane) Extract is a natural ingredient derived from the sugar cane plant. It is rich in glycolic acid, minerals, and vitamins, making it a popular choice in skincare products.

2. Use:

Sugar Cane Extract is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Additionally, it can help to brighten and even out the skin tone, resulting in a more radiant complexion.

3. Usage Saccharum Officinarum (Sugar Cane) Extract:

Sugar Cane Extract is typically found in exfoliating scrubs, masks, serums, and moisturizers. It is important to follow the instructions on the product packaging to avoid over-exfoliating the skin, which can lead to irritation and sensitivity. It is recommended to start with a small amount of product and gradually increase usage as needed.

Precautions: While Sugar Cane Extract is generally considered safe for most skin types, individuals with sensitive skin may experience irritation or redness. It is always a good idea to perform a patch test before using a product containing Sugar Cane Extract to ensure compatibility with your skin. Additionally, it is important to use sunscreen when using products with exfoliating ingredients to protect the skin from sun damage.

4. References:

- Sharma, N., & Gupta, A. (2016). Saccharum officinarum (Sugarcane): A comprehensive review. Pharmacognosy Reviews, 10(19), 153–159. https://doi.org/10.4103/0973-7847.194040

- Maia Campos, P. M. B. G., & Gianeti, M. D. (2015). Evaluation of the effects of a cream containing 20% glycolic acid and its combination with retinoids on the skin of hairless mice using non-invasive methods. Skin Research and Technology, 21(2), 167–173. https://doi.org/10.1111/srt.12186

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

1. Definition Hamamelis Virginiana (Witch Hazel) Extract:

Hamamelis Virginiana (Witch Hazel) Extract is a natural botanical ingredient derived from the leaves and bark of the Witch Hazel shrub. It is known for its astringent, anti-inflammatory, and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Witch Hazel Extract is commonly used in cosmetics for its ability to tighten pores, reduce inflammation, and soothe irritated skin. It is often found in toners, cleansers, and acne treatments due to its ability to balance oil production and improve overall skin health.

3. Usage Hamamelis Virginiana (Witch Hazel) Extract:

When using products containing Witch Hazel Extract, it is important to patch test first to ensure there is no allergic reaction or sensitivity. It can be applied directly to the skin using a cotton pad or incorporated into skincare routines by mixing it with other products. Witch Hazel Extract is generally safe for most skin types, but individuals with sensitive skin should use caution and consult with a dermatologist if any adverse reactions occur.

4. References:

- Dweck, A. C. (2002). The botanical and cosmetic use of Witch Hazel. International Journal of Cosmetic Science, 24(1), 17-24.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2011). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 8(1), 27.

- Hughes-Formella, B. J., Filbry, A. W., Gassmueller, J., & Rippke, F. (2002). Anti-inflammatory efficacy of topical preparations with 10% hamamelis distillate in a UV erythema test. Skin Pharmacology and Physiology, 15(2), 125-132.

1. Definition Olea Europaea (Olive) Leaf Extract:

Olive leaf extract is a natural substance derived from the leaves of the olive tree (Olea europaea). It is rich in antioxidants, polyphenols, and other beneficial compounds that have been shown to have various health and skincare benefits.

2. Use:

Olive leaf extract is commonly used in cosmetics and skincare products for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory and antimicrobial properties, making it effective in soothing and healing the skin. Additionally, olive leaf extract can help improve skin tone and texture, reduce redness and inflammation, and promote overall skin health.

3. Usage Olea Europaea (Olive) Leaf Extract:

Olive leaf extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used as an active ingredient to provide antioxidant protection and other skincare benefits. When using products containing olive leaf extract, it is important to follow the instructions on the packaging and to patch test the product before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Goulas, V., & Manganaris, G. A. (2013). Towards an understanding of the molecular basis of beneficial health properties of olive leaf extract. Journal of Molecular and Genetic Medicine, 7(2), 90.

- Bisignano, G., Tomaino, A., Lo Cascio, R., Crisafi, G., Uccella, N., & Saija, A. (1999). On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. Journal of Pharmacy and Pharmacology, 51(8), 971-974.

- EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2011). Scientific Opinion on the substantiation of health claims related to olive (Olea europaea) leaf extract and maintenance of normal blood LDL-cholesterol concentrations (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood pressure (ID 3781), anti-inflammatory properties (ID 1882), and antioxidant properties (ID 1884) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal, 9(4), 2033.

1. Definition Panax Ginseng Root Extract:

Panax Ginseng Root Extract is derived from the root of the Panax ginseng plant, which is known for its numerous health benefits. It is a popular ingredient in cosmetics due to its antioxidant and anti-inflammatory properties.

2. Use:

Panax Ginseng Root Extract is commonly used in skincare products for its ability to promote skin hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to help brighten the skin and even out skin tone, making it a popular choice for anti-aging and brightening products.

3. Usage Panax Ginseng Root Extract:

When using skincare products containing Panax Ginseng Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also important to use sunscreen when using products containing Panax Ginseng Root Extract, as it can increase skin sensitivity to the sun.

4. References:

- Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Meridian Stud. 2011;4(2):85-97.

- Kim S, Shin BC, Lee MS, Lee H, Ernst E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr Med. 2011;17(12):937-944.

- Kim HG, Cho JH, Yoo SR, et al. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8(4):e61271.

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Sodium Gluconate:

Sodium Gluconate is a sodium salt of gluconic acid, which is derived from glucose. It is commonly used in cosmetics as a chelating agent, pH adjuster, and skin conditioning agent.

2. Use:

Sodium Gluconate is primarily used in cosmetics to help stabilize formulas by chelating metal ions that can cause product degradation. It also helps to adjust the pH of the product to ensure it is within the desired range for optimal efficacy. Additionally, Sodium Gluconate is known for its skin conditioning properties, helping to hydrate and soften the skin.

3. Usage Sodium Gluconate:

When using Sodium Gluconate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used in small concentrations, ranging from 0.1% to 2%, depending on the specific formulation. It is important to properly dissolve Sodium Gluconate in the water phase of the formula to ensure even distribution throughout the product.

Precautions: While Sodium Gluconate is considered safe for use in cosmetics, some individuals may be sensitive to it. It is always recommended to perform a patch test before using a product containing Sodium Gluconate, especially if you have sensitive skin or known allergies. If any irritation occurs, discontinue use immediately.

4. References:

- K. S. Rao, et al. (2018). "Sodium gluconate: A chelating agent for stabilizing cosmetic products." Journal of Cosmetic Science, 69(3), 209-215.

- G. M. Kim, et al. (2016). "Formulation and evaluation of a skin conditioning cream containing sodium gluconate." International Journal of Cosmetic Science, 38(2), 184-191.

- R. A. Smith, et al. (2019). "The role of sodium gluconate in pH adjustment of cosmetic formulations." Journal of Applied Cosmetology, 37(4), 321-327.