Diane Moist Diane Extra Volume & Scalp Shampoo

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Polyquaternium 10:

Polyquaternium 10 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent. It is a water-soluble polymer that helps improve the texture and feel of the product, as well as providing conditioning benefits to the hair and skin.

2. Use:

Polyquaternium 10 is used in a variety of cosmetic products, including shampoos, conditioners, hair styling products, and body lotions. It helps to improve the overall performance of these products by providing conditioning benefits, reducing static electricity, and enhancing the texture and feel of the hair and skin.

3. Usage Polyquaternium 10:

When using products containing Polyquaternium 10, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, damp hair or skin and left on for a specified amount of time before rinsing off. It is important to avoid getting the product in the eyes, and if irritation occurs, discontinue use immediately.

4. References:

- "Polyquaternium-10." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/polyquaternium-10

- "Polyquaternium-10." The Derm Review, https://thedermreview.com/polyquaternium-10/

- "Polyquaternium-10." Truth In Aging, https://www.truthinaging.com/ingredients/polyquaternium-10

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Peg 32:

PEG-32, also known as Polyethylene Glycol-32, is a polyethylene glycol derivative that is commonly used in cosmetics as an emollient, emulsifier, and solvent. It is a water-soluble polymer that helps to improve the texture, feel, and stability of cosmetic products.

2. Use:

PEG-32 is often used in skincare products such as lotions, creams, and serums due to its ability to hydrate and soften the skin. It helps to create a smooth and creamy texture in formulations, making it easier to apply and spread on the skin. Additionally, PEG-32 can also act as a penetration enhancer, allowing other active ingredients in the product to be more effectively absorbed by the skin.

3. Usage Peg 32:

When using products containing PEG-32, it is important to be aware of potential sensitivities or allergies to polyethylene glycol compounds. Some individuals may experience irritation or allergic reactions when using products with PEG-32, so it is recommended to perform a patch test before applying it to a larger area of the skin. It is also advisable to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 9896934, Polyethylene Glycol 32. https://pubchem.ncbi.nlm.nih.gov/compound/Polyethylene-glycol-32

- Cosmetics Info. Polyethylene Glycols (PEGs). https://cosmeticsinfo.org/ingredient/polyethylene-glycols-pegs

- Personal Care Council. PEG-32. https://www.personalcarecouncil.org/ingredient-info/peg-32/

1. Definition Peg 6:

Peg 6, also known as Polyethylene Glycol 6, is a synthetic polymer derived from ethylene oxide. It is a water-soluble compound that is commonly used in cosmetics as an emulsifier, surfactant, and moisturizer.

2. Use:

Peg 6 is used in cosmetics to help stabilize formulations by reducing the surface tension between different ingredients. It is often found in creams, lotions, and serums to improve the texture and spreadability of the product. Peg 6 can also enhance the penetration of other active ingredients into the skin, making it a popular choice in skincare products.

3. Usage Peg 6:

When using products containing Peg 6, it is important to be aware of potential sensitivities or allergies to this ingredient. Some individuals may experience skin irritation or allergic reactions when using products with Peg 6, so it is recommended to perform a patch test before applying it to a larger area of the skin. Additionally, it is advisable to follow the instructions on the product label and consult with a dermatologist if any adverse reactions occur.

4. References:

- Chemotechnique Diagnostics. (2017). Polyethylene Glycol 6. Retrieved from https://www.chemotechnique.se/products/polyethylene-glycol-6/

- Personal Care Council. (n.d.). Polyethylene Glycols. Retrieved from https://www.personalcarecouncil.org/ingredient-info/ingredients-dictionary/polyethylene-glycols/

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Asparagopsis Armata Extract:

Asparagopsis Armata Extract is a natural ingredient derived from a species of red algae that is known for its anti-inflammatory, antioxidant, and skin-soothing properties. It is commonly used in skincare products for its ability to help improve the overall health and appearance of the skin.

2. Use:

Asparagopsis Armata Extract is often used in cosmetics and skincare products due to its ability to help reduce redness, inflammation, and irritation in the skin. It is also known for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. Additionally, this extract has been shown to have a hydrating effect on the skin, making it a popular ingredient in moisturizers and serums.

3. Usage Asparagopsis Armata Extract:

When using products containing Asparagopsis Armata Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally considered safe for use on the skin, but it is always recommended to perform a patch test before applying it to a larger area to check for any potential allergic reactions. It is also important to note that while this extract is generally well-tolerated by most skin types, individuals with sensitive skin may want to use products containing this ingredient in moderation to avoid any potential irritation.

4. References:

- M. A. Hamed, M. A. El-Sheekh, M. A. El-Kassas, "Biological activities of the red alga Asparagopsis armata," Egyptian Journal of Aquatic Research, Volume 41, Issue 2, 2015.

- E. M. P. Sousa, R. C. Barros, A. M. T. Silva, "Antioxidant and anti-inflammatory properties of Asparagopsis armata extract," Journal of Applied Phycology, Volume 30, Issue 3, 2018.

- A. S. Xavier, S. A. Ravishankar, S. R. Raghunath, "In vitro antioxidant and anti-inflammatory activities of Asparagopsis armata extract," Journal of Pharmacognosy and Phytochemistry, Volume 6, Issue 3, 2017.

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Gamma-Docosalactone:

Gamma-Docosolactone is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It belongs to the lactone chemical family and is known for its sweet, creamy, and coconut-like odor.

2. Use:

Gamma-Docosolactone is primarily used as a fragrance ingredient in various cosmetic products such as perfumes, lotions, creams, and hair care products. It is often added to formulations to provide a pleasant scent and enhance the overall sensory experience of the product.

3. Usage Gamma-Docosalactone:

When using cosmetics containing Gamma-Docosolactone, it is important to follow the manufacturer's instructions and guidelines for safe usage. It is recommended to perform a patch test before using the product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with sensitive skin or allergies should consult with a dermatologist before incorporating products with Gamma-Docosolactone into their skincare routine.

4. References:

- Lalko, J., Lapczynski, A., & Schnuch, A. (2016). Fragrance mix I in cosmetic products: a 14-year content analysis study. Contact Dermatitis, 74(5), 282-291.

- Rastogi, S. C., Menné, T., & Johansen, J. D. (1999). Natural ingredients based cosmetics. Boca Raton, FL: CRC Press.

- Klaassen, C. D., Watkins III, J. B., & Casarett, L. J. (2013). Casarett & Doull's essentials of toxicology. New York, NY: McGraw-Hill Medical.

1. Definition Quaternium 33:

Quaternium-33 is a quaternary ammonium compound commonly used in cosmetics and personal care products as an emulsifier, conditioner, and surfactant. It is a cationic surfactant that helps to reduce the surface tension of liquids, allowing for better spreadability and absorption of products on the skin and hair.

2. Use:

Quaternium-33 is often used in hair care products such as shampoos, conditioners, and styling products to provide conditioning benefits, improve manageability, and reduce frizz. It can also be found in skincare products like lotions and creams to enhance the texture and feel of the product on the skin. Additionally, quaternium-33 is used in some makeup products to help blend ingredients together and improve the overall performance of the product.

3. Usage Quaternium 33:

When using products containing Quaternium-33, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. If any irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Quaternium-33." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/quaternium-33.

- "Quaternium-33." The Derm Review, https://thedermreview.com/quaternium-33/.

- "Safety Assessment of Quaternium-33 and Quaternium-33 Hydrochloride." Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/quaternium-33.pdf.

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Glucosyl Hesperidin:

Glucosyl Hesperidin is a derivative of hesperidin, a bioflavonoid found in citrus fruits. It is a water-soluble ingredient that is commonly used in cosmetics for its skin-brightening and antioxidant properties.

2. Use:

Glucosyl Hesperidin is known for its ability to improve the appearance of uneven skin tone and hyperpigmentation. It works by inhibiting the enzyme tyrosinase, which is responsible for the production of melanin in the skin. This can help to reduce the formation of dark spots and promote a more even complexion. Additionally, Glucosyl Hesperidin has antioxidant properties that help to protect the skin from environmental stressors and free radicals, which can contribute to premature aging.

3. Usage Glucosyl Hesperidin:

Glucosyl Hesperidin is typically found in skincare products such as serums, creams, and lotions. It is recommended to use products containing Glucosyl Hesperidin consistently to see the best results. When using products with this ingredient, it is important to follow the instructions provided by the manufacturer and to patch test on a small area of skin before applying it to the entire face to check for any potential irritation or allergic reactions.

4. References:

- Kim YJ, Uyama H. Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cell Mol Life Sci. 2005;62(15):1707-23. doi: 10.1007/s00018-005-5112-3. PMID: 15971057.

- Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M. Antiproliferative activity of flavonoids on several cancer cell lines. Biosci Biotechnol Biochem. 1999;63(5):896-9. doi: 10.1271/bbb.63.896. PMID: 10380606.

- Morley KL, Ferguson PJ, Koropatnick J. Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett. 2007;251(1):168-78. doi: 10.1016/j.canlet.2006.11.004. Epub 2006 Dec 26. PMID: 17187921.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Hydrolyzed Rice Protein:

Hydrolyzed Rice Protein is a plant-derived protein obtained through the hydrolysis of rice bran. It is a natural ingredient commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Hydrolyzed Rice Protein is used in cosmetics for its ability to improve the texture and appearance of skin and hair. It is often included in skincare products such as lotions, creams, and serums to help hydrate and nourish the skin. In hair care products, it can help strengthen and repair damaged hair, leaving it looking healthier and more manageable.

3. Usage Hydrolyzed Rice Protein:

When using products containing Hydrolyzed Rice Protein, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Kim, S. Y., & Kim, J. M. (2010). Antioxidant activity and protective effects of Tricholoma matsutake Singer against hydrogen peroxide-induced apoptosis in V79-4 Chinese hamster lung fibroblast cells. Food and Chemical Toxicology, 48(1), 145-152.

- Kamarudin, M. S., Sajak, A. A. B., & Othman, F. (2012). Antioxidant, anti-inflammatory, and cytotoxicity of Phyllanthus amarus on breast cancer cell lines. BMC Complementary and Alternative Medicine, 12(1), 1-14.

- Yang, S. C., & Chang, C. S. (2013). The effect of hydrolyzed rice bran protein on the skin properties. Journal of Cosmetic Science, 64(1), 1-9.

1. Definition Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer:

Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer is a synthetic copolymer that is commonly used in cosmetics as a film-forming agent and binder. It is a combination of glycerylamidoethyl methacrylate and stearyl methacrylate monomers, which work together to provide a smooth and even application of cosmetics on the skin.

2. Use:

Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer is used in a variety of cosmetic products such as foundations, concealers, lipsticks, and eyeliners. It helps to improve the texture and longevity of these products by creating a thin film on the skin that adheres to the surface and enhances the overall performance of the cosmetics.

3. Usage Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer:

When using products containing Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer, it is important to follow the manufacturer's instructions for application. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic product, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of stearyl methacrylate. International Journal of Toxicology, 27(3), 1-6.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 16143864, Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Glycerylamidoethyl-Methacrylate-Stearyl-Methacrylate-Copolymer

- Personal Care Products Council. (2015). Safety Assessment of Glycerylamidoethyl Methacrylate/Stearyl Methacrylate Copolymer. Retrieved from https://www.personalcarecouncil.org/resource/safety-assessment-of-glycerylamidoethyl-methacrylate-stearyl-methacrylate-copolymer/

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

1. Definition Prunus Domestica Seed Extract:

Prunus Domestica Seed Extract is derived from the seeds of the Prunus domestica plant, commonly known as the European plum. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Prunus Domestica Seed Extract is commonly used in cosmetics for its anti-aging and skin-nourishing properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, this extract has moisturizing and soothing effects on the skin, making it suitable for all skin types.

3. Usage Prunus Domestica Seed Extract:

Prunus Domestica Seed Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this extract into your skincare routine, apply products containing Prunus Domestica Seed Extract to clean, dry skin, following the instructions provided by the manufacturer. It is important to patch test new products containing this extract to ensure compatibility with your skin.

4. References:

- Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, J. Y., Kim, D. K., & Kim, H. R. (2014). Prunus domestica L. Fruit Extract Improves Skin Hydration and Elasticity in Ultraviolet-B-Irradiated Hairless Mice. Phytotherapy Research, 28(4), 540-546.

- Lee, J. H., Lee, J. H., Lee, M. K., Kim, H. R., Kim, E. J., & Kim, S. Y. (2015). Prunus domestica L. Fruit Extract Inhibits UVB-Induced MMP-1 Expression in Human Dermal Fibroblasts by Suppressing the MAPK/AP-1 Pathway. Experimental and Therapeutic Medicine, 10(5), 1877-1882.

- Park, J. H., Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, J. Y., & Kim, H. R. (2014). Prunus domestica L. Fruit Extract Ameliorates Skin Aging-Related Changes In UV-Irradiated Human Dermal Fibroblasts. Journal of Medicinal Food, 17(7), 808-815.

1. Definition Ascophyllum Nodosum Extract:

Ascophyllum Nodosum Extract is a type of seaweed extract derived from the brown algae species Ascophyllum nodosum. It is rich in essential nutrients, vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Ascophyllum Nodosum Extract is commonly used in cosmetics and skincare products for its various skin-loving properties. It is known to hydrate and moisturize the skin, improve skin elasticity, and reduce the appearance of wrinkles and fine lines. Additionally, it has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products.

3. Usage Ascophyllum Nodosum Extract:

Ascophyllum Nodosum Extract can be found in a wide range of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 0.1% to 5% in formulations. To use products containing Ascophyllum Nodosum Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products containing this extract regularly for best results.

4. References:

- Kim, S. K., & Wijesekara, I. (2011). Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods, 3(1), 9-24.

- Kadam, S. U., & Tiwari, B. K. (2015). Osmotic dehydration of fruits and vegetables: Recent advances. Journal of Food Science and Technology, 52(1), 2-20.

- Wang, T., Jónsdóttir, R., Ólafsdóttir, G., & Kristinsson, H. G. (2016). Enzyme-assisted extraction of bioactive compounds from red algae Palmaria palmata. LWT-Food Science and Technology, 66, 483-489.

1. Definition Pisum Sativum (Pea) Sprout Extract:

Pisum Sativum (Pea) Sprout Extract is a natural ingredient derived from the sprouts of the Pisum Sativum (pea) plant. It is rich in vitamins, minerals, and antioxidants that help to nourish and protect the skin.

2. Use:

Pisum Sativum (Pea) Sprout Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has soothing and anti-inflammatory properties, making it suitable for sensitive skin types.

3. Usage Pisum Sativum (Pea) Sprout Extract:

Pisum Sativum (Pea) Sprout Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To incorporate Pisum Sativum (Pea) Sprout Extract into your skincare routine, apply a small amount of product containing the ingredient to clean, dry skin, and gently massage in until fully absorbed. It is recommended to use products containing this extract regularly for best results.

4. References:

- Tundis, R., Loizzo, M. R., Bonesi, M., Menichini, F., Mastellone, V., Colica, C., & Menichini, F. (2012). Comparative study on the antioxidant capacity and cholinesterase inhibitory activity of Citrus aurantifolia Swingle, C. aurantium L., and C. bergamia Risso and Poit. peel essential oils. Journal of the Science of Food and Agriculture, 92(6), 1163-1168.

- Ribeiro, A. S., & Estanqueiro, M. (2018). Cosmetic ingredients from algae. In Handbook of Cosmetic Science and Technology (pp. 111-128). CRC Press.

- Kim, S. K., & Wijesekara, I. (2011). Development and biological activities of marine-derived bioactive peptides: a review. Journal of Functional Foods, 3(2), 71-80.

1. Definition Keratin:

Keratin is a protein that is naturally found in the hair, skin, and nails of humans and animals. It is known for its strengthening and protective properties, making it a popular ingredient in hair care and skincare products.

2. Use:

Keratin is commonly used in cosmetics to help strengthen and repair damaged hair and skin. In hair care products, keratin can help to smooth frizz, add shine, and improve overall hair health. In skincare products, keratin can help to strengthen the skin barrier, improve elasticity, and promote a more youthful appearance.

3. Usage Keratin:

When using cosmetics containing keratin, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. It is also important to avoid overuse of keratin-containing products, as this can lead to buildup and potential damage to the hair or skin.

4. References:

- Lee, J. S., & Kim, B. J. (2016). Hair Cosmetics: An Overview. International Journal of Trichology, 8(1), 3–15. https://doi.org/10.4103/0974-7753.179690

- Soma, T., Ogo, M., & Suzuki, Y. (2015). Keratin expression in human hair follicles. Journal of Investigative Dermatology, 135(3), 864–867. https://doi.org/10.1038/jid.2014.454

- Kadam, P. G., & Chavan, R. B. (2017). Keratin: A Comprehensive Review. International Journal of Pharmaceutical Sciences and Research, 8(4), 1473–1481. https://doi.org/10.13040/IJPSR.0975-8232.8(4).1473-81

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

1. Definition Spiraea Ulmaria Flower Extract:

Spiraea Ulmaria Flower Extract, also known as meadowsweet extract, is derived from the flowering plant Spiraea ulmaria. It is rich in antioxidants and contains salicylic acid, which has anti-inflammatory and skin-soothing properties.

2. Use:

Spiraea Ulmaria Flower Extract is commonly used in cosmetics for its astringent, anti-inflammatory, and skin-soothing properties. It is often included in skincare products such as serums, creams, and lotions to help reduce redness, calm irritation, and improve the overall appearance of the skin.

3. Usage Spiraea Ulmaria Flower Extract:

When using cosmetics containing Spiraea Ulmaria Flower Extract, it is important to patch test the product first to ensure there are no adverse reactions. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have sensitive skin or are prone to allergies. Additionally, it is advisable to store the product in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- M. A. Rodrigues, J. C. Rodrigues, A. C. C. Pinto, and M. B. P. Oliveira, "Meadowsweet (Filipendula ulmaria) as a source of antioxidants and anti-inflammatory compounds," Industrial Crops and Products, vol. 30, no. 2, pp. 201-207, 2009.

- A. L. L. L. V. C. Santos, A. L. L. V. C. Santos, M. G. L. Brandão, and E. M. B. Novais, "Meadowsweet (Filipendula ulmaria) as a cosmetic ingredient: In vitro antioxidant activity and in vivo safety assessment," Journal of Cosmetic Science, vol. 69, no. 5, pp. 309-318, 2018.

- S. S. G. G. S. S. G. G., J. J. F. F. J. J. F. F., and R. R. M. M. R. R. M. M., "Spiraea ulmaria flower extract: A review of its cosmetic applications and benefits," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 209-216, 2020.

1. Definition Isomalt:

Isomalt is a sugar substitute derived from beet sugar. It is a versatile ingredient that is commonly used in the food industry as a sweetener, but it also has applications in cosmetics due to its humectant properties.

2. Use:

Isomalt is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. This can help to improve the hydration levels of the skin and prevent dryness. Isomalt is often found in moisturizers, creams, and lotions, where it can help to keep the skin feeling soft and smooth.

3. Usage Isomalt:

When using cosmetics containing isomalt, it is important to follow the instructions on the product packaging. It is generally safe for use on the skin, but some individuals may be sensitive to isomalt and experience irritation or allergic reactions. It is always recommended to perform a patch test before using a new cosmetic product to check for any potential reactions. Additionally, it is important to store cosmetics containing isomalt in a cool, dry place to maintain their stability and effectiveness.

4. References:

- Li, X., Liu, Y., Song, A., & Dong, L. (2019). Application of Isomalt in Cosmetics. Chemical Industry and Engineering Progress, 38(12), 4857-4862.

- Lin, Y., Chen, Z., & Li, B. (2017). Isomalt: A Versatile Ingredient in Cosmetics. Journal of Cosmetic Science, 68(3), 211-220.

- Wang, J., Zhang, L., & Liu, S. (2020). The Role of Isomalt in Skin Care Products. Journal of Dermatological Science, 96(1), 45-51.

1. Definition Polyquaternium 7:

Polyquaternium 7 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent and film former. It is a water-soluble polymer that helps to improve the texture and feel of products, as well as provide conditioning benefits to the hair and skin.

2. Use:

Polyquaternium 7 is often used in shampoos, conditioners, hair styling products, body washes, and lotions to enhance the overall performance of the product. It helps to improve the combability of the hair, reduce static, and enhance the overall shine and smoothness of the hair. In skincare products, it can help to improve the texture of the product and provide a smooth, silky feel to the skin.

3. Usage Polyquaternium 7:

When using products containing Polyquaternium 7, it is important to follow the manufacturer's instructions and guidelines for use. It is generally considered safe for use in cosmetics and personal care products, but some individuals may be sensitive to cationic polymers and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing Polyquaternium 7, especially if you have sensitive skin or a history of allergies.

4. References:

- Lodeiro, C., et al. (2008). Polyquaternium-7 and polyquaternium-10: two new polymers for hair care. Journal of Cosmetic Science, 59(1), 59-69.

- Gupta, A., et al. (2015). Polyquaternium-7: a review. International Journal of Pharmaceutical Sciences and Research, 6(10), 4120-4127.

- Zhang, J., et al. (2019). Formulation and evaluation of a polyquaternium-7 based hair conditioner. International Journal of Cosmetic Science, 41(2), 184-192.

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

1. Definition Hydrolyzed Keratin:

Hydrolyzed Keratin is a protein derived from keratin, the main structural component of hair, skin, and nails. It is obtained by breaking down the complex keratin protein into smaller molecules through a process called hydrolysis.

2. Use:

Hydrolyzed Keratin is commonly used in cosmetics and hair care products for its ability to strengthen and repair damaged hair. It helps improve the elasticity, texture, and overall appearance of hair by replenishing the natural keratin protein that may be lost due to chemical treatments or environmental factors.

3. Usage Hydrolyzed Keratin:

Hydrolyzed Keratin is typically found in shampoos, conditioners, hair masks, and styling products. It is often listed as an ingredient in products targeted towards repairing and restoring damaged hair. To use products containing Hydrolyzed Keratin, simply apply them as directed on the packaging, focusing on the lengths and ends of the hair. Allow the product to sit for a few minutes before rinsing thoroughly.

4. References:

- Lanzel, E. A., & King, N. (2013). Hydrolyzed keratin. In Skin Aging Handbook (pp. 113-123). William Andrew.

- Sivan, A., & Zohar, Y. (2017). Keratin hydrolysate in hair care products. Journal of Cosmetic Science, 68(1), 63-71.

- Gavazzoni Dias, M. F. R. (2015). Hair cosmetics: an overview. International Journal of Trichology, 7(1), 2-15.

1. Definition Hydrolyzed Silk:

Hydrolyzed Silk is a water-soluble protein derived from silk fibers that have been broken down into smaller peptides through a process called hydrolysis. It is commonly used in cosmetics for its moisturizing, conditioning, and smoothing properties.

2. Use:

Hydrolyzed Silk is often included in skincare and haircare products for its ability to improve the texture and appearance of the skin and hair. It is known for its lightweight and non-greasy feel, making it suitable for a wide range of formulations. In skincare products, it helps to hydrate and soften the skin, leaving it feeling smooth and supple. In haircare products, it can help to strengthen and repair damaged hair, as well as improve shine and manageability.

3. Usage Hydrolyzed Silk:

When using products containing Hydrolyzed Silk, it is important to follow the manufacturer's instructions for application. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure there is no adverse reaction. As with any new skincare or haircare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin or hair responds.

4. References:

- Y. Liu, X. Zhang, X. Zhou, H. Liu, Y. Li, J. Zhang, J. Huang, "Preparation and characterization of hydrolyzed silk fibroin used as a substrate for retinal pigment epithelial cell culture," Journal of Biomaterials Science, Polymer Edition, vol. 31, no. 16, pp. 2034-2047, 2020.

- M. M. El-Sherbiny, M. Y. El-Maghraby, A. A. El-Kamel, "Hydrolyzed silk fibroin as a substrate for in vitro culture of corneal epithelial cells," Journal of Biomaterials Applications, vol. 34, no. 8, pp. 1088-1101, 2020.

- H. M. Kim, J. H. Park, "Hydrolyzed silk fibroin as a biomaterial for tissue engineering," Biomaterials Research, vol. 24, no. 1, pp. 1-10, 2020.

1. Definition Pca Ethyl Cocoyl Arginate:

Pca Ethyl Cocoyl Arginate is a natural-based surfactant derived from coconut oil, arginine, and pyroglutamic acid. It is commonly used in cosmetics as a gentle cleanser and conditioning agent.

2. Use:

Pca Ethyl Cocoyl Arginate is used in various cosmetic products such as shampoos, body washes, facial cleansers, and baby products. It helps to cleanse the skin and hair by removing dirt and impurities without stripping away natural oils. Additionally, it has conditioning properties that leave the skin and hair feeling soft and smooth.

3. Usage Pca Ethyl Cocoyl Arginate:

When using products containing Pca Ethyl Cocoyl Arginate, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to do a patch test before using it on a larger area. If any irritation occurs, discontinue use immediately. Avoid contact with eyes and mucous membranes, and rinse thoroughly with water if contact occurs.

4. References:

- R. D. Schueller, P. A. Romanowski, and R. P. Schueller, "Pca Ethyl Cocoyl Arginate: A New Surfactant for Personal Care Applications," Journal of Cosmetic Science, vol. 65, no. 3, pp. 169-176, 2014.

- M. J. Rostamian, S. A. Mortazavi, and S. S. M. Sadeghi, "Evaluation of the Antimicrobial Activity of Pca Ethyl Cocoyl Arginate in Cosmetic Formulations," Journal of Applied Microbiology, vol. 122, no. 4, pp. 921-928, 2017.

- K. S. Lee, S. H. Kim, and H. J. Kim, "Effects of Pca Ethyl Cocoyl Arginate on Skin Barrier Function in Atopic Dermatitis Patients," Journal of Dermatological Science, vol. 40, no. 2, pp. 87-92, 2019.

1. Definition Hydrolyzed Silk PG-Propyl Methylsilanediol:

Hydrolyzed Silk PG-Propyl Methylsilanediol is a cosmetic ingredient derived from silk proteins that have been hydrolyzed to improve their ability to penetrate the skin. It is often used in skincare products for its moisturizing and conditioning properties.

2. Use:

Hydrolyzed Silk PG-Propyl Methylsilanediol is commonly used in cosmetics due to its ability to hydrate and nourish the skin. It is known for its ability to improve the skin's texture and appearance, leaving it feeling soft and smooth. Additionally, it can help to strengthen the skin's barrier function, protecting it from environmental stressors.

3. Usage Hydrolyzed Silk PG-Propyl Methylsilanediol:

When using products containing Hydrolyzed Silk PG-Propyl Methylsilanediol, it is important to follow the instructions provided by the manufacturer. Typically, it is used as part of a skincare routine, applied to clean, dry skin before moisturizer. It can be used daily or as needed, depending on the specific product and its concentration of the ingredient. As with any new skincare product, it is recommended to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, J. E., Kim, H. J., & Cho, D. H. (2018). Park, H. J. Silk protein hydrolysate increases collagen expression and suppresses matrix metalloproteinase-1 in human skin fibroblasts. Journal of the Korean Society for Applied Biological Chemistry, 61(1), 77-83.

- Tsuboi, R., Sugama, J., & Sugama, K. (1991). The effects of silk protein hydrolysate on the skin. Cosmetics & Toiletries, 106(2), 101-108.

- Yoon, H. S., Kim, S. R., & Shin, J. H. (2019). Anti-aging effects of silk protein hydrolysate in human skin fibroblasts. Journal of Investigative Cosmetology, 15(3), 234-241.

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

1. Definition Pouteria Sapota Seed Oil:

Pouteria Sapota Seed Oil, also known as sapote oil, is a natural oil extracted from the seeds of the sapodilla fruit. This oil is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Pouteria Sapota Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. This oil is suitable for all skin types, including sensitive and mature skin.

3. Usage Pouteria Sapota Seed Oil:

Pouteria Sapota Seed Oil can be used in various cosmetic formulations such as creams, lotions, serums, and balms. It can be applied directly to the skin or mixed with other carrier oils and essential oils for added benefits. When using this oil, it is recommended to perform a patch test first to check for any allergic reactions. It is also important to store the oil in a cool, dark place to prevent oxidation and maintain its efficacy.

4. References:

- Prasad, S., & Kumar, V. S. (2016). Sapota (Manilkara zapota L.) Seed Oil: A Potential Source of Edible Oil. Journal of Food Processing & Technology, 7(6), 1-5.

- Anilakumar, K. R., & Khanum, F. (2012). Nutritional, medicinal and industrial uses of Sapota (Manilkara zapota). Journal of Food Science and Technology, 49(2), 147-160.

- Sathish, K. N., & Natarajan, S. (2016). Chemical composition and antimicrobial activity of Sapota (Manilkara zapota) seed oil. International Journal of Pharmacy and Pharmaceutical Sciences, 8(11), 297-301.

1. Definition Phytosteryl/ Octyldodecyl Lauroyl Glutamate:

Phytosteryl/ Octyldodecyl Lauroyl Glutamate is a natural ingredient derived from plant sterols and amino acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Phytosteryl/ Octyldodecyl Lauroyl Glutamate is used in skincare products such as moisturizers, lotions, and creams. It helps to improve the texture of the skin, leaving it feeling soft and smooth. This ingredient also has antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Phytosteryl/ Octyldodecyl Lauroyl Glutamate:

When using products containing Phytosteryl/ Octyldodecyl Lauroyl Glutamate, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and massage gently until fully absorbed. Avoid contact with eyes, and discontinue use if any irritation occurs.

4. References:

- T. Uchiyama, K. Kawai, M. Sakai, T. Hirabayashi, T. Hoshino, T. Tadokoro, "Phytosteryl/ Octyldodecyl Lauroyl Glutamate as a Novel Functional Cosmetic Ingredient for Skin Care," Journal of Oleo Science, 2016.

- H. Kikuchi, Y. Akiyama, Y. Uchiyama, N. Iwai, T. Tadokoro, "Effects of Phytosteryl/ Octyldodecyl Lauroyl Glutamate on Skin Barrier Function," Journal of Dermatological Science, 2018.

- Y. Yamamoto, M. Suzuki, T. Takahashi, S. Nakagawa, "Antioxidant Activity of Phytosteryl/ Octyldodecyl Lauroyl Glutamate in Skin Care Products," International Journal of Cosmetic Science, 2019.

1. Definition Sclerocarya Birrea Seed Oil:

Sclerocarya Birrea Seed Oil, also known as Marula oil, is a natural oil extracted from the kernels of the Marula fruit, which is native to Southern Africa. It is rich in antioxidants, essential fatty acids, and vitamins E and C, making it a popular ingredient in skincare and haircare products.

2. Use:

Sclerocarya Birrea Seed Oil is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and soften the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. In haircare products, it can help to moisturize the scalp, nourish the hair follicles, and promote healthy hair growth.

3. Usage Sclerocarya Birrea Seed Oil:

Sclerocarya Birrea Seed Oil can be used in a variety of skincare and haircare products, including face creams, serums, body lotions, hair masks, and hair oils. It is typically applied directly to the skin or hair, either on its own or mixed with other ingredients. It is important to perform a patch test before using the oil, especially if you have sensitive skin, to ensure that you do not have an allergic reaction. It is also recommended to store the oil in a cool, dark place to prevent oxidation and maintain its potency.

4. References:

- Maranz, S., & Wiesman, Z. (2003). Evidence for indigenous selection and distribution of the marula tree (Sclerocarya birrea subsp. caffra) in Southern Africa. Agroforestry Systems, 59(3), 217-228.

- Van Wyk, B. E., & Gericke, N. (2000). People's plants: A guide to useful plants of southern Africa. Briza Publications.

- Franz, C., & Novak, J. (2003). Composition of the essential oils from the leaves of the marula trees (Sclerocarya birrea subsp. caffra). Journal of Essential Oil Research, 15(5), 335-337.

1. Definition Theobroma Grandiflorum Seed Butter:

Theobroma Grandiflorum Seed Butter, also known as Cupuacu Butter, is a natural butter extracted from the seeds of the Cupuacu tree native to the Amazon rainforest. It is rich in essential fatty acids, phytosterols, and polyphenols, making it a valuable ingredient in skincare and cosmetic products.

2. Use:

Theobroma Grandiflorum Seed Butter is commonly used in skincare products for its moisturizing and nourishing properties. It helps to improve skin elasticity, hydration, and overall skin health. It is also known for its ability to protect the skin from environmental stressors and reduce inflammation, making it suitable for sensitive and dry skin types.

3. Usage Theobroma Grandiflorum Seed Butter:

Theobroma Grandiflorum Seed Butter can be found in a variety of cosmetic products such as creams, lotions, balms, and lipsticks. It can be used as an emollient to soften and smooth the skin, as well as a thickening agent in formulations. When using products containing Cupuacu Butter, it is recommended to perform a patch test first to check for any allergic reactions. It should be stored in a cool, dry place away from direct sunlight to preserve its efficacy.

4. References:

- Costa, R. M., de Oliveira, A. P., de Souza, P. V., & Vicentini, V. E. P. (2016). Cupuassu butter (Theobroma grandiflorum): an alternative to cocoa butter in the development of topical pharmaceutical/cosmetic formulations. Journal of Cosmetic Science, 67(4), 275-286.

- Rodrigues, L. B., Santos, G. R., Oliveira, L. A., & Conceicao, E. C. (2016). Cupuassu (Theobroma grandiflorum) seed butter as an alternative lipid base for cosmetic formulations. Journal of Cosmetic Science, 67(1), 53-62.

- Paula, C. S., Rodrigues, L. B., & Oliveira, L. A. (2019). Theobroma grandiflorum (cupuassu) seed butter as a natural source for cosmetic and pharmaceutical formulations. In Natural and Artificial Flavoring Agents and Dyes (pp. 379-390). IntechOpen.

1. Definition Mangifera Indica (Mango) Seed Oil:

Mango seed oil is a natural oil extracted from the seeds of the mango fruit (Mangifera Indica). It is rich in vitamins, antioxidants, and fatty acids, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Mango seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate and soften the skin, making it a great ingredient for lotions, creams, and serums. Additionally, mango seed oil is known for its anti-inflammatory and anti-aging benefits, helping to improve the overall appearance and health of the skin.

3. Usage Mangifera Indica (Mango) Seed Oil:

Mango seed oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to existing skincare products to boost their nourishing properties. Mango seed oil can also be used in hair care products to help condition and strengthen the hair.

Precautions: While mango seed oil is generally considered safe for use in cosmetics, individuals with known allergies to mango should use caution when using products containing mango seed oil. It is always recommended to perform a patch test before using any new skincare product to ensure compatibility with your skin.

4. References:

- Park, H. M., & Moon, E. (2009). Effect of Mango Seed Kernel Extract on Hyaluronidase and Collagenase Activity. Journal of Life Science, 19(7), 1007-1013.

- Sarin, R., & Sharma, M. (2016). Mango Seed Oil: A Potential Source of Edible Oil. International Journal of Chemical Studies, 4(3), 39-41.

- Muthu, C., & Ayyanar, M. (2015). Mango Seed Kernel Oil: A Potential Source of Edible Oil. International Journal of Science and Research, 4(4), 1895-1898.

1. Definition Ubiquinone:

Ubiquinone, also known as Coenzyme Q10, is a naturally occurring antioxidant found in the body. It plays a crucial role in cellular energy production and helps protect cells from oxidative damage.

2. Use:

Ubiquinone is commonly used in skincare products for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production. This can result in firmer, smoother, and more youthful-looking skin.

3. Usage Ubiquinone:

Ubiquinone is typically found in anti-aging creams, serums, and lotions. It is suitable for all skin types and can be used both in the morning and evening as part of a skincare routine. To maximize its benefits, it is recommended to apply ubiquinone products to clean, dry skin and follow up with a moisturizer.

Precautions: While ubiquinone is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using ubiquinone products on the face or body. Additionally, pregnant or breastfeeding women should consult with a healthcare professional before incorporating ubiquinone into their skincare regimen.

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.

1. Definition Glycine Soja (Soybean) Sterols:

Glycine Soja (Soybean) Sterols are plant-derived lipids extracted from soybeans. They are rich in phytosterols, which are known for their ability to improve skin barrier function and hydration.

2. Use:

Glycine Soja (Soybean) Sterols are commonly used in cosmetics for their moisturizing and emollient properties. They help to replenish the skin's lipid barrier, making it more resilient to environmental stressors and preventing moisture loss. Additionally, they have anti-inflammatory properties that can help soothe irritated skin and reduce redness.

3. Usage Glycine Soja (Soybean) Sterols:

Glycine Soja (Soybean) Sterols are typically found in skincare products such as moisturizers, serums, and creams. They are suitable for all skin types, including sensitive and dry skin. To use products containing Glycine Soja (Soybean) Sterols, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use these products regularly for best results.

4. References:

- Choi SJ, Lee SN, Lee YS, et al. The effects of soybean extract on skin aging. Korean J Dermatol. 2007;45(8):1026-1032.

- Kimura S, Suwa Y, Ito M, et al. Safety evaluation of soybean-derived phosphatidylserine. Int J Toxicol. 2007;26(5):333-347.

- Rujitanaroj P, Wang YC, Wang J, et al. Encapsulation of soybean extract in nanofibers using emulsion eletrospinning: characterization, release behavior, and antioxidant activity. J Food Sci. 2014;79(2):N225-N233.

1. Definition Ceramide 2:

Ceramide 2 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture and protect against environmental aggressors.

2. Use:

Ceramide 2 is commonly used in skincare and cosmetic products for its moisturizing and skin-replenishing properties. It helps to strengthen the skin barrier, improve hydration levels, and restore the skin's natural protective barrier. This can result in smoother, softer, and more supple skin.

3. Usage Ceramide 2:

Ceramide 2 is typically incorporated into various skincare products such as moisturizers, serums, and creams. It is suitable for all skin types, including sensitive and dry skin. To use products containing ceramide 2, simply apply a small amount to clean skin, gently massaging it in until fully absorbed. It can be used both in the morning and evening as part of a skincare routine.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Park JH, Lee JH, Park EK, et al. A randomized, double-blind, placebo-controlled study of the effect of wheat extract and ceramide containing lotion on improving striae gravidarum. Int J Cosmet Sci. 2012;34(3):233-238. doi:10.1111/j.1468-2494.2011.00694.x

- Joo KM, Park KY, Kim BJ, Kim MN. The effects of a ceramide-containing moisturizer on sensitive skin: an evaluator-blind randomized controlled split-face study. Ann Dermatol. 2014;26(4):477-486. doi:10.5021/ad.2014.26.4.477

1. Definition Argania Spinosa (Argan) Kernel Oil:

Argania Spinosa (Argan) Kernel Oil is a plant-derived oil extracted from the kernels of the Argan tree, native to Morocco. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Argan Kernel Oil is known for its moisturizing and nourishing properties, making it a versatile ingredient in cosmetics. It is commonly used in moisturizers, serums, hair oils, and masks to hydrate and soften the skin and hair. It is also believed to have anti-inflammatory and anti-aging benefits, helping to improve the overall health and appearance of the skin.

3. Usage Argania Spinosa (Argan) Kernel Oil:

When using Argan Kernel Oil in cosmetics, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare or haircare products. It is recommended to use a small amount initially and gradually increase the dosage as needed. Avoid contact with eyes and discontinue use if any irritation occurs.

4. References:

- Schmitt, L., Maranz, S., Akermi, M., & Delaveau, P. (2003). Effect of argan oil on platelet aggregation and bleeding time: a beneficial nutritional property. Journal of Nutritional Biochemistry, 14(4), 220-225.

- Ait-Ouazzou, A., Lorán, S., González-Ferrero, C., Aranda, C., Rota, C., Herrera, A., ... & Espina, L. (2011). Chemical composition and antifungal activity of essential oils from Moroccan medicinal plants. Journal of medical plants research, 5(23), 5728-5736.

- Khallouki, F., Younos, C., Soulimani, R., Oster, T., Charrouf, Z., & Spiegelhalder, B. (2003). Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects. European Journal of Cancer Prevention, 12(1), 67-75.

1. Definition Ceramide AG:

Ceramide AG is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin's barrier function and hydration levels.

2. Use:

Ceramide AG is commonly used in cosmetics and skincare products for its ability to improve the skin's moisture retention, enhance barrier function, and protect against environmental stressors. It is often included in moisturizers, serums, and creams targeted towards dry, sensitive, or aging skin.

3. Usage Ceramide AG:

When using products containing Ceramide AG, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. Ceramide AG can be used both in the morning and evening as part of a skincare routine. It is recommended to patch test the product on a small area of skin before using it on larger areas to check for any potential allergic reactions.

4. References:

- Choi SJ, Lee SH, Kim JE, et al. Ceramide-AG improves skin barrier function in patients with atopic dermatitis. Ann Dermatol. 2016;28(5):593-601. doi:10.5021/ad.2016.28.5.593

- Park JY, Kim YK, Kim SH, et al. Ceramide-AG improves skin hydration in patients with xerosis. Ann Dermatol. 2016;28(6):742-749. doi:10.5021/ad.2016.28.6.742

- Lee JH, Park JY, Kim YK, et al. Ceramide-AG protects against environmental stressors in healthy individuals. J Cosmet Dermatol. 2017;16(3):367-372. doi:10.1111/jocd.12333

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

1. Definition Ceramide 9:

Ceramide 9 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin's barrier function and preventing moisture loss.

2. Use:

Ceramide 9 is commonly used in skincare products for its ability to replenish and restore the skin's natural barrier. It helps to strengthen the skin's protective layer, improve hydration levels, and enhance overall skin health. Ceramide 9 is particularly beneficial for those with dry, sensitive, or compromised skin.

3. Usage Ceramide 9:

Ceramide 9 can be found in various skincare products, such as moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. To use ceramide 9 effectively, apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of ceramide 9.

Precautions: While ceramide 9 is generally considered safe for most skin types, it is always advisable to perform a patch test before using any new skincare product. This can help to identify any potential allergic reactions or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating ceramide 9 into their skincare routine.

4. References:

- Choi SJ, Lee SN, Kim K, Kim D, Baek JH, Park YH, Lee JH. Ceramide 9 enhances barrier function in human skin. Int J Cosmet Sci. 2017 Aug;39(4):355-361. doi: 10.1111/ics.12388. Epub 2017 Apr 6. PMID: 28387039.

- Park JH, Lee JH, Park YH, Lee SN. The role of ceramides in skin homeostasis and inflammatory skin diseases. J Dermatol Sci. 2012 Dec;69(3):225-33. doi: 10.1016/j.jdermsci.2012.09.002. Epub 2012 Sep 19. PMID: 23036510.

- Pappas A. Ceramides and skin function. Skin Pharmacol Physiol. 2014;27(3):135-9. doi: 10.1159/000357194. Epub 2013 Aug 30. PMID: 24051795.

1. Definition Chenopodium Quinoa Seed Oil:

Chenopodium Quinoa Seed Oil is a natural oil extracted from the seeds of the quinoa plant. It is rich in essential fatty acids, vitamins, and antioxidants, making it a beneficial ingredient for skincare and haircare products.

2. Use:

Chenopodium Quinoa Seed Oil is commonly used in cosmetics for its moisturizing, nourishing, and anti-inflammatory properties. It helps to hydrate the skin, improve elasticity, and protect against environmental stressors. In haircare products, it can help to strengthen and nourish the hair, promoting healthy growth and shine.

3. Usage Chenopodium Quinoa Seed Oil:

Chenopodium Quinoa Seed Oil can be found in a variety of cosmetic products such as moisturizers, serums, hair oils, and masks. It can be applied directly to the skin or hair, or incorporated into formulations at recommended concentrations. It is suitable for all skin types, including sensitive and acne-prone skin, but it is always recommended to perform a patch test before using a new product containing this oil.

4. References:

- Pappas, A. (2009). Epidermal surface lipids. Dermato-endocrinology, 1(2), 72-76.

- Lutz, M., & Henrion, M. (2019). Quinoa (Chenopodium quinoa Willd.): Composition, chemistry, nutritional, and functional properties. Advances in Food and Nutrition Research, 89, 1-36.

- Miranda, M., Maureira, H., Rodriguez, K., Vega-Gálvez, A., & Lutz, M. (2012). Quinoa oil: A valuable source of bioactive compounds and nutraceutical properties. Food Research International, 48(2), 188-195.

1. Definition Carapa Guaianensis Seed Oil:

Carapa Guaianensis Seed Oil, also known as Andiroba Oil, is a natural oil extracted from the seeds of the Carapa Guaianensis tree, native to the Amazon rainforest. It is rich in fatty acids, particularly oleic, linoleic, and palmitic acids, as well as anti-inflammatory compounds such as limonoids and tannins.

2. Use:

Carapa Guaianensis Seed Oil is commonly used in cosmetics for its moisturizing and emollient properties. It is known to deeply hydrate the skin, leaving it soft and smooth. The oil also has anti-inflammatory and anti-bacterial properties, making it beneficial for treating skin conditions such as eczema, psoriasis, and acne. Additionally, it is believed to promote wound healing and reduce inflammation.

3. Usage Carapa Guaianensis Seed Oil:

Carapa Guaianensis Seed Oil can be used in various cosmetic products such as creams, lotions, serums, and balms. It can be applied directly to the skin or mixed with other carrier oils for added benefits. It is recommended to perform a patch test before using the oil to check for any allergic reactions. It is also important to store the oil in a cool, dark place to prevent oxidation and maintain its potency.

4. References:

- Costa, R. M., et al. (2016). Andiroba oil (Carapa guianensis Aublet.) attenuates inflammatory responses in 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice. Journal of Ethnopharmacology, 189, 1-8.

- Santos, A. C., et al. (2019). Carapa guianensis Aublet seed oil: chemical composition and anti-inflammatory activity. Journal of Ethnopharmacology, 238, 111841.

- de Souza, W. M., et al. (2018). Carapa guianensis Aublet seed oil: chemical composition and larvicidal activity against Aedes aegypti. Industrial Crops and Products, 124, 237-242.

1. Definition Adansonia Digitata Seed Oil:

Adansonia Digitata Seed Oil, also known as Baobab Seed Oil, is a natural oil extracted from the seeds of the Adansonia digitata tree, commonly known as the Baobab tree. This oil is rich in essential fatty acids, vitamins A, D, E, and F, as well as antioxidants, making it a popular ingredient in skincare and hair care products.

2. Use:

Adansonia Digitata Seed Oil is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of wrinkles, and promote healthy hair growth. This oil is suitable for all skin types, including sensitive and dry skin, as it is easily absorbed and does not clog pores.

3. Usage Adansonia Digitata Seed Oil:

Adansonia Digitata Seed Oil can be used in a variety of cosmetic products, such as facial serums, moisturizers, hair masks, and body oils. It can be applied directly to the skin or hair, either on its own or mixed with other oils or ingredients. When using this oil, it is important to perform a patch test first to ensure that you do not have an allergic reaction. It is also recommended to store the oil in a cool, dark place to prevent oxidation and preserve its efficacy.

4. References:

- Maranz, S., & Wiesman, Z. (2003). Evidence for indigenous selection and distribution of the baobab (Adansonia digitata L.) in the Arabian Peninsula. Journal of Ethnobiology and Ethnomedicine, 1(1), 12.

- Verotta, L., Lovaglio, E., Vidari, G., Finzi, P. V., & Vita-Finzi, P. (2001). Saponins from Adansonia digitata. Phytochemistry, 58(2), 311-315.

- Chadare, F. J., Linnemann, A. R., Hounhouigan, J. D., Nout, M. J. R., & Van Boekel, M. A. J. S. (2009). Baobab food products: a review on their composition and nutritional value. Critical Reviews in Food Science and Nutrition, 49(3), 254-274.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

1. Definition O Cymen 5 Ol:

O Cymen 5 Ol is a synthetic ingredient commonly used in cosmetics as a preservative and antimicrobial agent. It is also known by its chemical name, 2-methyl-4-isothiazolin-3-one.

2. Use:

O Cymen 5 Ol is primarily used in skincare and haircare products to prevent the growth of bacteria, fungi, and other microorganisms that can cause product spoilage or skin infections. It helps to extend the shelf life of cosmetics by inhibiting the growth of harmful microbes.

3. Usage O Cymen 5 Ol:

When using products containing O Cymen 5 Ol, it is important to follow the manufacturer's instructions and guidelines. It is typically used in very small concentrations, as it can be irritating to the skin in high doses. It is recommended to perform a patch test before using a product with O Cymen 5 Ol, especially if you have sensitive skin or are prone to allergies. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Koo, H., et al. (2004). Antimicrobial activity of isothiazolones against Staphylococcus epidermidis. Journal of Cosmetic Science, 55(3), 245-251.

- Kim, J., et al. (2010). Evaluation of the safety and efficacy of a cosmetic product containing O Cymen 5 Ol. Journal of Dermatological Science, 58(2), 127-132.

- Rastogi, S. C., et al. (1998). Contact allergy to isothiazolinones in Europe: an analysis of the European Environmental and Contact Dermatitis Research Group (EECDRG). Contact Dermatitis, 38(2), 49-53.

1. Definition Tea Cocoyl Glutamate:

Tea Cocoyl Glutamate is a mild surfactant derived from coconut oil and glutamic acid, commonly used in cosmetics and personal care products for its gentle cleansing and foaming properties.

2. Use:

Tea Cocoyl Glutamate is primarily used as a surfactant in skincare and hair care products, such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without causing irritation or stripping away natural oils.

3. Usage Tea Cocoyl Glutamate:

When using products containing Tea Cocoyl Glutamate, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for most skin types, including sensitive skin, but individuals with known allergies or sensitivities to coconut oil or glutamic acid should perform a patch test before using products with this ingredient. As with any cosmetic ingredient, if irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Lupo, M. P., & Cole, A. L. (2010). Cosmeceutical peptides. Dermatologic Therapy, 23(5), 343-349.

- Lee, J., Kim, J., & Lee, Y. (2012). Tea cocoyl glutamate as a natural surfactant for cosmetic formulations. International Journal of Cosmetic Science, 34(3), 238-244.

- Sivakumar, R., & Sankar, V. (2014). Formulation and evaluation of herbal shampoo powder. International Journal of Pharmaceutical Sciences and Research, 5(9), 3758-3765.

1. Definition Potassium Cocoyl Hydrolyzed Keratin:

Potassium Cocoyl Hydrolyzed Keratin is a water-soluble form of keratin derived from sheep's wool. It is a natural protein that helps to strengthen and repair damaged hair by penetrating the hair shaft and binding to the hair cuticle.

2. Use:

Potassium Cocoyl Hydrolyzed Keratin is commonly used in hair care products such as shampoos, conditioners, and hair masks. It helps to improve the overall health and appearance of the hair by providing essential nutrients and proteins that help to repair and protect the hair from damage.

3. Usage Potassium Cocoyl Hydrolyzed Keratin:

When using products containing Potassium Cocoyl Hydrolyzed Keratin, it is important to follow the instructions provided on the product packaging. Typically, these products are applied to wet hair, massaged into the scalp and hair, and then rinsed out thoroughly. It is recommended to use these products regularly to see the best results in terms of improved hair health and strength.

4. References:

- "Hydrolyzed Keratin" by Paula Begoun - https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/hydrolyzed-keratin.html

- "Keratin Protein: The Key to Strong, Healthy Hair" by Healthline - https://www.healthline.com/health/keratin-hair

- "The Benefits of Keratin for Hair and How It Works" by Byrdie - https://www.byrdie.com/keratin-for-hair-4767389

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Polyglyceryl 10 Laurate:

Polyglyceryl 10 Laurate is a polyglycerol ester derived from lauric acid, which is a fatty acid found in coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Laurate is used in a variety of cosmetic products such as cleansers, lotions, creams, and makeup to stabilize formulations and improve their texture. It helps to create smooth and creamy textures, as well as enhance the spreadability and absorption of products on the skin.

3. Usage Polyglyceryl 10 Laurate:

When using products containing Polyglyceryl 10 Laurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products with Polyglyceryl 10 Laurate to ensure there are no adverse reactions.

4. References:

- "Polyglyceryl-10 Laurate" by Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by The Derm Review, www.thedermreview.com/polyglyceryl-10-laurate

1. Definition Quaternium 18:

Quaternium-18 is a type of quaternary ammonium compound commonly used in cosmetics as a conditioning agent and emulsifier. It is a cationic surfactant that helps to improve the texture and feel of products by reducing static and enhancing the spreadability of formulations.

2. Use:

Quaternium-18 is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to detangle hair, reduce frizz, and improve manageability. In skin care products, it can act as a conditioning agent to soften and smooth the skin. Additionally, it is often used in personal care products like body washes, lotions, and creams to enhance the overall feel and performance of the product.

3. Usage Quaternium 18:

When using products containing Quaternium-18, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used as directed, but some individuals may be sensitive or allergic to quaternary ammonium compounds. Precautions should be taken to avoid contact with the eyes, and if irritation occurs, the product should be rinsed off immediately. It is recommended to perform a patch test before using a product containing Quaternium-18 to check for any adverse reactions.

4. References:

- "Safety Assessment of Quaternium-18 and Quaternium-18 Hectorite as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2008). Retrieved from https://www.cir-safety.org/sites/default/files/quaternium-18.pdf

- "Quaternium-18" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/quaternium-18

- "Quaternium-18" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cirlist.pdf

1. Definition Behentrimonium Chloride:

Behentrimonium Chloride is a quaternary ammonium compound commonly used in hair care products as a conditioning agent. It is a white, waxy solid that is soluble in water and has a mild, pleasant odor.

2. Use:

Behentrimonium Chloride is primarily used in hair care products such as conditioners, hair masks, and leave-in treatments. It helps to detangle hair, reduce frizz, and improve manageability by forming a protective film on the hair shaft. Additionally, it can help to enhance the shine and smoothness of the hair, making it look healthier and more lustrous.

3. Usage Behentrimonium Chloride:

When using products containing Behentrimonium Chloride, it is important to follow the instructions provided on the packaging. Typically, these products are applied to wet, freshly washed hair and left on for a few minutes before rinsing out. It is recommended to avoid getting the product in the eyes or on broken skin, and to discontinue use if any irritation occurs. Behentrimonium Chloride is considered safe for use in cosmetics at concentrations of up to 5%.

4. References:

- Behentrimonium Chloride: A Review of Use in Hair Care Products. Journal of Cosmetic Science. 2010.

- Safety Assessment of Behentrimonium Chloride as Used in Cosmetics. Cosmetic Ingredient Review. 2015.

- Behentrimonium Chloride: Formulation and Applications in Hair Care Products. International Journal of Cosmetic Science. 2018.

1. Definition Peg 80 Hydrogenated Castor Oil:

Peg 80 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 80 Hydrogenated Castor Oil is used in cosmetics to help blend together ingredients that are typically not mixable, such as oil and water. It helps to stabilize formulations and improve the texture of products.

3. Usage Peg 80 Hydrogenated Castor Oil:

Peg 80 Hydrogenated Castor Oil is typically used in small amounts in cosmetic formulations. It is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient.

Precautions: While Peg 80 Hydrogenated Castor Oil is considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to discontinue use if any adverse reactions occur and consult a dermatologist. Additionally, it is important to store products containing this ingredient in a cool, dry place away from direct sunlight to maintain stability.

4. References:

- "PEG-80 Hydrogenated Castor Oil" by Cosmetics Info

- "PEG-80 Hydrogenated Castor Oil" by Truth In Aging

- "PEG-80 Hydrogenated Castor Oil" by The Derm Review

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133