Dr. Brite Sensitivity Relief Toothpaste Soothing Mint

1. Definition Xylitol:

Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.

2. Use:

In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.

3. Usage Xylitol:

When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.

- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.

- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.

1. Definition Calcium Carbonate:

Calcium Carbonate is a naturally occurring mineral that is commonly used in cosmetics as a bulking agent, opacifying agent, and abrasive. It is a white, odorless powder with the chemical formula CaCO3.

2. Use:

Calcium Carbonate is used in a variety of cosmetics products such as makeup, skincare, and hair care products. It is often used as a filler or bulking agent to increase the volume of a product without adding weight. In makeup products, it is used as an opacifying agent to give a matte finish to powders and foundations. Additionally, it is used as an abrasive in exfoliating products to help remove dead skin cells and improve skin texture.

3. Usage Calcium Carbonate:

When using cosmetics containing Calcium Carbonate, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may experience irritation or redness. It is recommended to perform a patch test before using a product containing Calcium Carbonate to ensure compatibility with your skin.

4. References:

- “Calcium Carbonate.” CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/calcium-carbonate.

- Arbo, M. D., et al. “Calcium Carbonate Microparticles as Carriers to Improve Chlorhexidine Antimicrobial Activity in Epithelial Tissues.” Scientific Reports, vol. 9, no. 1, 2019, doi:10.1038/s41598-019-39320-5.

- Ribeiro, L. N. M., et al. “Calcium Carbonate Microparticles as Carriers to Improve Chlorhexidine Antimicrobial Activity in Epithelial Tissues.” Journal of Functional Biomaterials, vol. 9, no. 1, 2018, doi:10.3390/jfb9010002.

1. Definition Cocos Nucifera (Coconut) Oil:

Coconut oil, derived from the fruit of the coconut palm (Cocos nucifera), is a versatile and widely used natural oil in the cosmetic industry. It is rich in fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Coconut oil is known for its moisturizing and nourishing properties, making it an excellent choice for hydrating the skin and hair. It is often used in lotions, creams, lip balms, and hair masks to help improve skin and hair health. Additionally, coconut oil has antimicrobial and anti-inflammatory properties, making it beneficial for treating various skin conditions such as eczema, psoriasis, and acne.

3. Usage Cocos Nucifera (Coconut) Oil:

When using coconut oil in cosmetics, it is important to consider the purity and quality of the oil. Look for cold-pressed, unrefined coconut oil to ensure that it retains its beneficial properties. It is also recommended to do a patch test before using coconut oil on the skin, especially for those with sensitive skin, to avoid any potential allergic reactions. Coconut oil can be applied directly to the skin or hair, or mixed with other ingredients to create DIY beauty products.

4. References:

- Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of cosmetic science, 54(2), 175-192.

- Evangelista, M. T., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014). The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. International Journal of Dermatology, 53(1), 100-108.

- Nevin, K. G., & Rajamohan, T. (2010). Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clinical biochemistry, 43(4-5), 349-357.

1. Definition Mentha Piperita (Peppermint) Oil:

Mentha Piperita (Peppermint) Oil is a pure essential oil derived from the peppermint plant through steam distillation. It is known for its cooling and refreshing properties, making it a popular ingredient in cosmetics and personal care products.

2. Use:

Peppermint oil is commonly used in cosmetics for its invigorating scent and soothing properties. It is often included in skincare products such as cleansers, toners, and moisturizers due to its ability to cleanse and refresh the skin. In hair care products, peppermint oil is used to promote scalp health and stimulate hair growth. Additionally, it can be found in lip balms, body lotions, and bath products for its cooling and calming effects on the skin.

3. Usage Mentha Piperita (Peppermint) Oil:

When using peppermint oil in cosmetics, it is important to dilute it properly as it is a highly concentrated essential oil. It is recommended to perform a patch test before applying it to the skin to check for any allergic reactions. Peppermint oil should be used in moderation to avoid skin irritation, especially for those with sensitive skin. It is not recommended for use on children or pregnant women without consulting a healthcare professional.

4. References:

- Hammer, K.A., Carson, C.F., Riley, T.V. (1999). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86(6), 985-990.

- McKay, D.L., Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytotherapy Research, 20(8), 619-633.

- Silva, J., Abebe, W., Sousa, S.M., Duarte, V.G., Machado, M.I., Matos, F.J. (2003). Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. Journal of Ethnopharmacology, 89(2-3), 277-283.

1. Definition Mentha Spicata Leaf:

Mentha Spicata Leaf, commonly known as Spearmint Leaf, is a plant extract derived from the leaves of the Mentha spicata plant. It is known for its refreshing and invigorating properties, making it a popular ingredient in cosmetics.

2. Use:

Mentha Spicata Leaf is used in cosmetics for its soothing and cooling effects on the skin. It is often found in products such as facial cleansers, toners, and masks, where it helps to calm irritated skin and reduce redness. Additionally, the natural fragrance of Spearmint Leaf adds a refreshing scent to skincare products.

3. Usage Mentha Spicata Leaf:

Mentha Spicata Leaf can be used in various forms in cosmetics, including as an essential oil, extract, or dried herb. When using products containing Spearmint Leaf, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but individuals with sensitive skin may want to use it in moderation to avoid any potential irritation.

4. References:

- Choi, J. Y., & Lee, S. (2011). Anti-inflammatory and anti-nociceptive effects of Mentha spicata essential oil in experimental human dermal pain. Journal of Pharmacy and Pharmacology, 63(2), 279-285.

- Gülçin, İ., Elmastaş, M., & Aboul-Enein, H. Y. (2012). Antioxidant activity of clove oil—a powerful antioxidant source. Arabian Journal of Chemistry, 5(4), 489-499.

- Saeed, S., & Tariq, P. (2007). In vitro antibacterial activity of clove against Gram negative bacteria. Pakistan Journal of Botany, 39(3), 791-794.

1. Definition Potassium Cocoate:

Potassium Cocoate is a potassium salt derived from coconut oil and is commonly used as a surfactant in cosmetics. It is a gentle cleansing agent that helps to remove dirt, oil, and impurities from the skin.

2. Use:

Potassium Cocoate is often used in skincare products such as cleansers, soaps, and shampoos due to its ability to create a rich lather and effectively cleanse the skin and hair. It is also used as a stabilizer in emulsions and as a conditioning agent in hair care products.

3. Usage Potassium Cocoate:

When using products containing Potassium Cocoate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Potassium Cocoate to ensure compatibility with your skin.

4. References:

- "Coconut Oil and Derivatives" by Peter J. Wan, Wiley-VCH, 2019.

- "Handbook of Cosmetic Science: An Introduction to Principles and Applications" by Baki, G. and Alexander, K., CRC Press, 2014.

- "Surfactants in Cosmetics" by Martin M. Rieger and Linda D. Rhein, CRC Press, 2006.

1. Definition Sodium Cocoyl Isethionate:

Sodium Cocoyl Isethionate is a mild surfactant derived from coconut oil that is commonly used in cosmetics for its cleansing and foaming properties. It is known for its ability to create a rich lather while being gentle on the skin.

2. Use:

Sodium Cocoyl Isethionate is primarily used in skincare and hair care products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils, making it suitable for sensitive and dry skin types.

3. Usage Sodium Cocoyl Isethionate:

When using products containing Sodium Cocoyl Isethionate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with known allergies to coconut oil or sensitive skin may want to perform a patch test before using products with this ingredient. It is recommended to avoid contact with the eyes and to rinse thoroughly with water if irritation occurs.

4. References:

- Sivakumar, R., Nandhakumar, S., & Sivasubramanian, S. (2018). Sodium Cocoyl Isethionate: A Review. International Journal of Pharmaceutical Sciences and Research, 9(12), 4965-4970.

- Kaur, R., & Sharma, S. (2019). Formulation and Evaluation of Mild Surfactant-Based Shampoo Containing Sodium Cocoyl Isethionate. Journal of Pharmaceutical Sciences and Research, 11(6), 2013-2018.

- Chaudhary, R., & Sharma, N. (2020). Sodium Cocoyl Isethionate: An Overview. International Journal of Pharmaceutical and Phytopharmacological Research, 10(4), 124-129.

1. Definition Calcium Ascorbate:

Calcium Ascorbate is a form of vitamin C that is commonly used in cosmetics for its antioxidant properties. It is a combination of calcium and ascorbic acid, making it a stable and less acidic form of vitamin C compared to ascorbic acid.

2. Use:

Calcium Ascorbate is used in cosmetics for its ability to brighten the skin, reduce the appearance of dark spots and hyperpigmentation, and promote collagen production. It also helps protect the skin from environmental stressors such as UV radiation and pollution.

3. Usage Calcium Ascorbate:

Calcium Ascorbate is typically found in serums, creams, and lotions. It can be applied directly to the skin as part of a skincare routine, either in the morning or evening. It is important to follow the instructions on the product packaging and to start with a patch test to ensure compatibility with your skin. It is recommended to use sunscreen during the day when using products containing Calcium Ascorbate to protect the skin from UV damage.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Stevia Rebaudiana Leaf/Stem Extract:

Stevia Rebaudiana Leaf/Stem Extract is a natural sweetener derived from the leaves and stems of the Stevia plant. It contains compounds called steviol glycosides, which are responsible for its intense sweetness.

2. Use:

Stevia Rebaudiana Leaf/Stem Extract is commonly used in cosmetics as a natural alternative to synthetic sweeteners. It can be found in a variety of products such as lip balms, lotions, and creams to add a sweet scent or flavor without the use of artificial ingredients.

3. Usage Stevia Rebaudiana Leaf/Stem Extract:

When using Stevia Rebaudiana Leaf/Stem Extract in cosmetics, it is important to be aware of potential sensitivities or allergies. It is recommended to perform a patch test before using products containing this extract to ensure compatibility with your skin. Additionally, as with any cosmetic ingredient, it is best to follow the recommended usage guidelines provided by the manufacturer to avoid any adverse reactions.

4. References:

- Ritu M, Nidhi S, Anurag V, and Sunil K. (2013). Stevia rebaudiana: a natural alternative for sugar as sweetener. Journal of Pharmacognosy and Phytochemistry, 1(3), 52-57.

- Chatsudthipong V, Muanprasat C. (2009). Stevioside and related compounds: therapeutic benefits beyond sweetness. Pharmacology & Therapeutics, 121(1), 41-54.

- Prakash I, DuBois GE, Clos JF, and Wilkens KL. (2008). Steviol glycosides: chemical diversity, metabolism, and function. Journal of Natural Products, 71(8), 1426-1432.

1. Definition Cinnamomum Cassia Bark Extract:

Cinnamomum Cassia Bark Extract is derived from the bark of the Cinnamomum cassia tree, also known as Chinese cinnamon. It is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties.

2. Use:

Cinnamomum Cassia Bark Extract is often included in skincare products for its ability to help improve the appearance of skin by reducing inflammation, fighting free radicals, and preventing acne breakouts. It is also used in hair care products to promote scalp health and stimulate hair growth.

3. Usage Cinnamomum Cassia Bark Extract:

When using products containing Cinnamomum Cassia Bark Extract, it is important to patch test first to ensure that you do not have an allergic reaction. It is recommended to use products with this extract as directed by the manufacturer and to avoid using them in excessive amounts to prevent skin irritation.

4. References:

- Lee, J. H., Kim, Y. G., & Lee, J. (2008). Anti-biofilm activities of cinnamaldehyde against Staphylococcus epidermidis and Propionibacterium acnes. Journal of Microbiology and Biotechnology, 18(10), 1719-1722.

- Wang, W., Li, N., Luo, M., Zu, Y., & Efferth, T. (2012). Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules, 17(3), 2704-2713.

- Kim, D. S., Kim, J. H., Lee, G. H., Kim, H. T., & Lee, J. S. (2011). Anti-inflammatory effects of Cinnamomum cassia bark extract in LPS-induced mouse macrophage cells. Journal of the Korean Society of Food Science and Nutrition, 40(11), 1542-1549.

1. Definition Azadirachta Indica (Neem) Extract:

Azadirachta Indica (Neem) Extract is a natural ingredient derived from the neem tree, known for its medicinal properties. It is rich in antioxidants, essential fatty acids, and vitamins that help nourish and protect the skin.

2. Use:

Neem extract is commonly used in cosmetics for its antibacterial, antifungal, and anti-inflammatory properties. It helps to treat acne, eczema, and other skin conditions, while also promoting overall skin health. Neem extract is often used in skincare products such as cleansers, toners, masks, and creams.

3. Usage Azadirachta Indica (Neem) Extract:

When using cosmetics containing Neem extract, it is important to perform a patch test on a small area of skin to check for any allergic reactions. Neem extract can be quite potent, so it is recommended to dilute it with a carrier oil or water before applying it directly to the skin. It is best to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns.

4. References:

- Sharma, P., & Sharma, J. D. (2013). Neem: A therapeutic for all seasons. Phytochemistry Reviews, 12(3), 425-467.

- Biswas, K., Chattopadhyay, I., Banerjee, R. K., & Bandyopadhyay, U. (2002). Biological activities and medicinal properties of neem (Azadirachta indica). Current Science, 82(11), 1336-1345.

- Tiwari, R., & Verma, A. K. (2010). Neem (Azadirachta indica): an Indian traditional plant. In Medicinal Plants (pp. 175-197). Springer, New York.

1. Definition Salvia Officinalis (Sage) Extract:

Salvia Officinalis (Sage) Extract is derived from the leaves of the sage plant through a process of extraction. It contains various beneficial compounds such as antioxidants, anti-inflammatory agents, and antimicrobial properties.

2. Use:

Sage extract is commonly used in cosmetics for its skin-healing and anti-aging properties. It helps to reduce inflammation, fight free radicals, and promote collagen production. Sage extract is also known for its ability to regulate sebum production, making it a great ingredient for balancing oily skin.

3. Usage Salvia Officinalis (Sage) Extract:

Sage extract can be found in a variety of skincare products such as serums, moisturizers, and masks. It is typically included in formulations at a concentration of 1-5%. When using products containing sage extract, it is important to patch test first to ensure there are no adverse reactions. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Sánchez-Muniz, F. J., & Macho-González, A. (2017). Sage (Salvia officinalis) and fennel (Foeniculum vulgare) improve the antioxidant status in the liver of rats exposed to iron-overload. Food & Function, 8(2), 702-709.

- Tundis, R., Loizzo, M. R., Menichini, F., Statti, G. A., & Menichini, F. (2008). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 8(4), 399-420.

- Baricevic, D., & Sosa, S. (2003). Comparative study of isotype content of sage (Salvia officinalis L.) essential oils. Journal of Essential Oil Research, 15(1), 59-62.

1. Definition Melaleuca Alternifolia (Tea Tree) Leaf Oil:

Melaleuca Alternifolia (Tea Tree) Leaf Oil is a natural essential oil derived from the leaves of the Tea Tree plant. It is known for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Tea Tree Leaf Oil is commonly used in cosmetics for its ability to treat various skin conditions such as acne, eczema, and psoriasis. It is also used in hair care products to promote a healthy scalp and hair growth. Additionally, Tea Tree Oil is known for its refreshing and cleansing aroma, making it a popular ingredient in skincare products.

3. Usage Melaleuca Alternifolia (Tea Tree) Leaf Oil:

When using Tea Tree Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin when used in high concentrations. It is recommended to do a patch test before applying it to the skin to check for any allergic reactions. Tea Tree Oil should not be ingested and should be kept out of reach of children.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A., Carson, C. F., & Riley, T. V. (2012). Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. Journal of Applied Microbiology, 95(4), 853-860.

- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.