Name: E-Rezept Kaufen Adapaben
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Adapalene

Other Names: Adaplene; Differin

Function: Antiacne Agent

1. Definition Adapalene:

Adapalene is a synthetic compound that belongs to the class of medications known as retinoids. It is commonly used in the treatment of acne, as it helps to unclog pores, reduce inflammation, and promote skin cell turnover.

2. Use:

Adapalene is primarily used in the formulation of topical treatments for acne, such as gels, creams, and lotions. It is known for its ability to target multiple factors that contribute to acne formation, making it a popular choice among dermatologists and skincare professionals.

3. Usage Adapalene:

When using products containing Adapalene, it is important to follow the instructions provided by a healthcare professional or included on the product packaging. Typically, Adapalene should be applied to clean, dry skin once daily, preferably in the evening. It is important to avoid excessive sun exposure while using Adapalene, as it can increase the skin's sensitivity to UV radiation. Additionally, some individuals may experience mild irritation or dryness when first using Adapalene, but these side effects usually subside with continued use.

4. References:

- Dreno, B., Thiboutot, D., Gollnick, H., Finlay, A.Y., Layton, A., Leyden, J.J., & Kang, S. (2009). Large-scale worldwide observational study of adherence with acne therapy. International Journal of Dermatology, 48(7), 749-756.

- Thielitz, A., Gollnick, H., & Reinhold, D. (2008). Adapalene as a treatment for acne vulgaris: a retrospective analysis of data from the German Acne Registry. Journal of the European Academy of Dermatology and Venereology, 22(6), 787-794.

- Leyden, J.J., Wortzman, M., & Baldwin, E.K. (2011). A single-center, randomized double-blind, parallel-group study to examine the safety and efficacy of 0.1% Adapalene gel compared to vehicle in the treatment of acne vulgaris in adult females. Journal of Drugs in Dermatology, 10(6), 582-587.

Benzoyl Peroxide

Function: Antiacne Agent, Oxidising Agent

1. Definition Benzoyl Peroxide:

Benzoyl Peroxide is a topical medication commonly used in skincare products to treat acne. It works by reducing the amount of acne-causing bacteria on the skin and helping to unclog pores.

2. Use:

Benzoyl Peroxide is primarily used in over-the-counter and prescription acne treatments, such as creams, gels, and washes. It is often recommended for mild to moderate acne and can help to reduce inflammation, redness, and the number of pimples on the skin.

3. Usage Benzoyl Peroxide:

When using products containing Benzoyl Peroxide, it is important to follow the instructions provided by the manufacturer or healthcare provider. Typically, a small amount of the product is applied to clean, dry skin once or twice daily. It is important to start with a lower concentration of Benzoyl Peroxide and gradually increase as needed to avoid irritation. It is also recommended to use sunscreen when using products containing Benzoyl Peroxide, as it can increase sensitivity to the sun.

4. References:

- Draelos, Z. D. (2016). Over-the-counter acne treatments. Dermatologic clinics, 34(2), 175-184.

- Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Bhushan, R. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.

- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Layton, A. M. (2019). Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 81(3), 775-789.

Benzoic Acid

Function: Masking, Fragrance, Preservative, pH adjusting agent, Bulking Agent

1. Definition Benzoic Acid:

Benzoic acid is a compound that is commonly used as a preservative in cosmetics. It is a white, crystalline powder with a faint, pleasant odor.

2. Use:

Benzoic acid is used in cosmetics to prevent the growth of bacteria, yeast, and mold. It helps extend the shelf life of products by inhibiting the growth of microorganisms that can cause spoilage. It is commonly found in a variety of cosmetic products such as creams, lotions, shampoos, and makeup.

3. Usage Benzoic Acid:

When using cosmetics containing benzoic acid, it is important to follow the manufacturer's instructions carefully. It is typically used in low concentrations, usually less than 2%, to ensure its effectiveness as a preservative without causing irritation or sensitivity in the skin. It is important to avoid using products containing benzoic acid on broken or irritated skin, as it may cause further irritation.

Precautions: While benzoic acid is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing benzoic acid to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate." Int J Toxicol. 2001;20 Suppl 3:23-50.

- "Benzoic Acid." CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/benzoic-acid.

- "Benzoic Acid." PubChem, National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/Benzoic-acid.

Disodium Edetate

Ingredient data is being updated. Please check back later.

Water

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Docusate Sodium

Ingredient data is being updated. Please check back later.

Glycerol

Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

Poloxamer 124

Function: Surfactant, Emulsifying

1. Definition Poloxamer 124:

Poloxamer 124 is a non-ionic surfactant that belongs to the family of synthetic block copolymers. It is composed of hydrophilic polyethylene oxide (PEO) and hydrophobic polypropylene oxide (PPO) blocks, which give it surfactant properties.

2. Use:

Poloxamer 124 is commonly used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients in formulations, stabilize emulsions, and improve the texture and feel of products. It is often found in creams, lotions, shampoos, and other skincare products.

3. Usage Poloxamer 124:

When using products containing Poloxamer 124, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with Poloxamer 124, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Y. Zhang, X. Hu, L. Wang, Y. Zhang, "A novel solid dispersion system of Poloxamer 124 with felodipine," Drug Development and Industrial Pharmacy, 2010.

- M. K. Singh, A. V. Chauhan, "Poloxamers: A pharmaceutical excipient with therapeutic behaviors," International Journal of Pharmaceutical Sciences and Research, 2016.

- L. Li, W. Zhang, Y. Zhang, "The effect of Poloxamer 124 on the stability of O/W emulsions," Journal of Dispersion Science and Technology, 2018.

Propylene Glycol

Other Names: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol

Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a combination of acrylamide and sodium acryloyldimethyltaurate, which helps to create a smooth and creamy texture in skincare products.

2. Use:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is used in a wide range of cosmetics, including moisturizers, sunscreens, serums, and lotions. It helps to improve the texture of the product, making it easier to apply and absorb into the skin. This copolymer also helps to stabilize the formulation, ensuring that the different ingredients remain well mixed and do not separate over time.

3. Usage Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

When using products containing Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, it is important to follow the instructions provided by the manufacturer. This copolymer is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. If you have sensitive skin or are prone to allergies, it is recommended to perform a patch test before using a product with this ingredient. Additionally, avoid contact with the eyes and mouth, and if irritation occurs, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of acrylamide/sodium acryloyldimethyltaurate copolymer. International Journal of Toxicology, 32(1), 46S-66S.

- Personal Care Products Council. (2018). Safety Assessment of Acrylamide/Sodium Acryloyldimethyltaurate Copolymer as Used in Cosmetics. Cosmetic Ingredient Review.

- Loretz, L. J., Api, A. M., Barraj, L. M., Burdick, J., Davis de Borba, B., Dressler, W. E., ... & Wilcox, D. K. (2005). Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food and Chemical Toxicology, 43(2), 279-289.

Isohexadecane

Function: Solvent, Skin Conditioning, Emollient

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

+ Polysorbate 80 (Vegetable)

Other Names: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate

Function: Denaturant , Emulsifying, Surfactant

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

Sorbitan Oleate

Function: Fragrance, Emulsifying, Surfactant

1. Definition Sorbitan Oleate:

Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.

3. Usage Sorbitan Oleate:

When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.

4. References:

- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate

- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf

- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate

Water Purified

Ingredient data is being updated. Please check back later.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
-	-	Adapalene (Antiacne Agent)	Acne fighting
3	-	Benzoyl Peroxide (Antiacne Agent, Oxidising Agent)	Acne fighting
1 3	A	Benzoic Acid (Masking, Fragrance, Preservative, pH adjusting agent, Bulking Agent)	Bad for sensitive skin
-	-	Disodium Edetate
1	-	Water (Solvent)
-	-	Docusate Sodium
1 2	A	Glycerol (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin Moisturizing
2	A	Poloxamer 124 (Surfactant, Emulsifying)	Cleansing
3	B	Propylene Glycol (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous)	Good for dry skin
1 2	-	Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer (Viscosity Controlling, Emulsion Stabilising)
1	B	Isohexadecane (Solvent, Skin Conditioning, Emollient)
3	B	+ Polysorbate 80 (Vegetable) (Denaturant , Emulsifying, Surfactant)	Fungal Acne Trigger Cleansing
1	A	Sorbitan Oleate (Fragrance, Emulsifying, Surfactant)	Bad for oily skin Fungal Acne Trigger Cleansing
-	-	Water Purified

E-Rezept Kaufen Adapaben

Ingredients

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Ingredient List