Ella & Jo Wide Awake Eye Gel

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

1. Definition Ceramide 9:

Ceramide 9 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin's barrier function and preventing moisture loss.

2. Use:

Ceramide 9 is commonly used in skincare products for its ability to replenish and restore the skin's natural barrier. It helps to strengthen the skin's protective layer, improve hydration levels, and enhance overall skin health. Ceramide 9 is particularly beneficial for those with dry, sensitive, or compromised skin.

3. Usage Ceramide 9:

Ceramide 9 can be found in various skincare products, such as moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. To use ceramide 9 effectively, apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of ceramide 9.

Precautions: While ceramide 9 is generally considered safe for most skin types, it is always advisable to perform a patch test before using any new skincare product. This can help to identify any potential allergic reactions or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating ceramide 9 into their skincare routine.

4. References:

- Choi SJ, Lee SN, Kim K, Kim D, Baek JH, Park YH, Lee JH. Ceramide 9 enhances barrier function in human skin. Int J Cosmet Sci. 2017 Aug;39(4):355-361. doi: 10.1111/ics.12388. Epub 2017 Apr 6. PMID: 28387039.

- Park JH, Lee JH, Park YH, Lee SN. The role of ceramides in skin homeostasis and inflammatory skin diseases. J Dermatol Sci. 2012 Dec;69(3):225-33. doi: 10.1016/j.jdermsci.2012.09.002. Epub 2012 Sep 19. PMID: 23036510.

- Pappas A. Ceramides and skin function. Skin Pharmacol Physiol. 2014;27(3):135-9. doi: 10.1159/000357194. Epub 2013 Aug 30. PMID: 24051795.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Phytosphingosine:

Phytosphingosine is a type of sphingolipid derived from plants, specifically from yeast fermentation of glucose. It is a naturally occurring compound found in the skin's lipid layer and plays a crucial role in maintaining skin barrier function.

2. Use:

Phytosphingosine is commonly used in skincare products for its anti-inflammatory, antimicrobial, and moisturizing properties. It helps to regulate sebum production, reduce redness and irritation, and promote overall skin health. Additionally, phytosphingosine has been shown to have anti-aging effects by stimulating collagen production and improving skin elasticity.

3. Usage Phytosphingosine:

Phytosphingosine can be found in various skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 0.1% to 1% and can be applied topically to the skin. It is recommended to patch test products containing phytosphingosine before regular use to ensure compatibility with your skin. It is also important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.

- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.

1. Definition Caffeine:

Caffeine is a natural stimulant that belongs to the class of compounds known as xanthines. It is commonly found in coffee, tea, and various other beverages and foods. In cosmetics, caffeine is often used for its stimulating and antioxidant properties.

2. Use:

Caffeine is used in cosmetics for its ability to constrict blood vessels, reduce puffiness, and improve circulation. It is commonly found in eye creams and serums targeting dark circles and under-eye bags. Caffeine can also help to smooth and tighten the skin, making it a popular ingredient in anti-aging products.

3. Usage Caffeine:

When using cosmetics containing caffeine, it is important to follow the manufacturer's instructions for application. Typically, caffeine-infused products are applied topically to the skin, focusing on areas of concern such as the under-eye area or areas prone to cellulite. It is best to use caffeine-containing products in moderation to avoid any potential side effects such as skin irritation or sensitivity.

4. References:

- Mukherjee, P. K., & Maity, N. (2012). Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate cognitive impairments. In Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease (pp. 605-619). Academic Press.

- Costa, R., Rodrigues, I., Guardão, L., Lima, J. L., & Fernandes, E. (2012). Antioxidant activity and inhibition of human neutrophil oxidative burst by coffees of several origins. Food and Chemical Toxicology, 50(5), 1435-1441.

- Albasini, A., Zech, K., & Taddei, C. (2012). Use of caffeine in cosmetic compositions. U.S. Patent No. 8,119,371.

1. Definition Euphrasia Officinalis Extract:

Euphrasia Officinalis Extract, also known as eyebright extract, is derived from the flowering plant Euphrasia officinalis. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Euphrasia Officinalis Extract is often included in skincare products for its ability to reduce redness, puffiness, and irritation around the eyes. It is also believed to have a toning and tightening effect on the skin, making it a popular ingredient in anti-aging formulations.

3. Usage Euphrasia Officinalis Extract:

Euphrasia Officinalis Extract can be found in various cosmetic products such as eye creams, serums, and facial masks. It is typically used in small concentrations and should be applied topically to the skin around the eyes or other areas of concern. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of the skin to avoid any potential allergic reactions.

4. References:

- Chizzola R. (2018). Composition of the essential oil of Euphrasia officinalis L. ssp. rostkoviana (Hayne) Soó from Austria. Natural Product Communications, 13(5), 561-564.

- Schilcher H. (2012). Phytotherapy in Paediatrics: Handbook for Physicians and Pharmacists. CRC Press.

- European Medicines Agency. (2010). Assessment report on Euphrasia officinalis L., herba. Retrieved from https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-euphrasia-officinalis-l-herba_en.pdf

1. Definition Punica Granatum Extract:

Punica Granatum Extract, also known as pomegranate extract, is derived from the fruit of the Punica granatum tree. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Punica Granatum Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and moisturizing properties. It helps to improve skin texture, increase collagen production, and protect the skin from environmental damage.

3. Usage Punica Granatum Extract:

Punica Granatum Extract can be found in various skincare products such as serums, creams, and masks. It is typically added to formulations in small concentrations to provide its benefits without causing irritation. To use products containing Punica Granatum Extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer and sunscreen for optimal results.

4. References:

- Aslam MN, Lansky EP, Varani J. Pomegranate as a cosmeceutical source: Pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. J Ethnopharmacol. 2006;103(3):311-318. doi:10.1016/j.jep.2005.08.016

- Mphahlele RR, Fawole OA, Mokwena LM, Opara UL. Pomegranate fruit quality: A review. Food Bioprocess Technol. 2014;7(1):34-57. doi:10.1007/s11947-013-1181-1

- Li Y, Guo C, Yang J, Wei J, Xu J, Cheng S. Evaluation of antioxidant properties of pomegranate peel extract in comparison with pomegranate pulp extract. Food Chem. 2006;96(2):254-260. doi:10.1016/j.foodchem.2005.02.033

1. Definition Camellia Sinensis (Green Tea) Leaf Extract:

Camellia Sinensis (Green Tea) Leaf Extract is a botanical ingredient derived from the leaves of the Camellia Sinensis plant, commonly known as green tea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products. Additionally, green tea extract can help soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Camellia Sinensis (Green Tea) Leaf Extract:

Green tea extract can be found in a variety of skincare products, including serums, moisturizers, masks, and eye creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing green tea extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing green tea extract before full application to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Hyun, C. G., & Shin, S. (2009). Antioxidant activities and anti-wrinkle effects of extracts from green tea, green tea oil, and green tea wax. Journal of the American Oil Chemists' Society, 86(6), 601-608.

- Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green tea and skin. Archives of Dermatology, 136(8), 989-994.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Coffea Arabica (Coffee) Seed Extract:

Coffea Arabica (Coffee) Seed Extract is derived from the seeds of the Coffea Arabica plant, commonly known as coffee. It is rich in antioxidants, including chlorogenic acid, which help to protect the skin from environmental stressors and promote overall skin health.

2. Use:

Coffee seed extract is commonly used in skincare products for its antioxidant properties, which can help to reduce inflammation, improve skin texture, and protect against UV damage. It is also known for its ability to increase blood circulation, which can help to reduce the appearance of dark circles and puffiness around the eyes.

3. Usage Coffea Arabica (Coffee) Seed Extract:

Coffee seed extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effects. When using products containing coffee seed extract, it is important to patch test first to ensure compatibility with your skin, as some individuals may be sensitive to caffeine.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Maia Campos, P. M. B. G., Gianeti, M. D., & Camargo, F. B., Jr (2014). Evaluation of the antioxidant capacity of coffea arabica L. in cosmetic formulations by in vitro methods. Anais Brasileiros de Dermatologia, 89(6), 1027–1031. https://doi.org/10.1590/abd1806-4841.20142980

- Micek, J., & Żywicka, B. (2015). Antioxidative properties of coffee substitutes. Acta Scientiarum Polonorum Technologia Alimentaria, 14(1), 61–70. https://doi.org/10.17306/J.AFS.2015.1.7

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Lactobacillus Ferment Lysate:

Lactobacillus Ferment Lysate is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is known for its ability to balance the skin's microbiome, promote healthy bacteria growth, and improve the overall health of the skin.

2. Use:

Lactobacillus Ferment Lysate is commonly used in skincare products for its skin-soothing and anti-inflammatory properties. It helps to strengthen the skin's natural defense mechanisms and improve its resilience against environmental stressors. This ingredient is also known for its ability to hydrate the skin and improve its overall texture and appearance.

3. Usage Lactobacillus Ferment Lysate:

Lactobacillus Ferment Lysate can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied to the skin both in the morning and evening as part of a regular skincare routine. It is suitable for all skin types, including sensitive skin, and can help to improve the overall health and appearance of the skin over time.

4. References:

- Choi, S. Y., Kim, H. J., & Ko, H. C. (2015). Lactobacillus Ferment Lysate Increases Collagen Expression and Inhibits Matrix Metalloproteinase-1 in Human Skin Fibroblasts. Annals of Dermatology, 27(1), 58–63. https://doi.org/10.5021/ad.2015.27.1.58

- Kim, S., Kim, H. J., & Ko, H. C. (2019). Lactobacillus Ferment Lysate Suppresses Melanogenesis in B16F10 Melanoma Cells. Annals of Dermatology, 31(6), 647–652. https://doi.org/10.5021/ad.2019.31.6.647

- Lee, S. H., & Lee, S. H. (2018). Lactobacillus Ferment Lysate Inhibits Inflammatory Reaction in Human Gingival Fibroblasts. Journal of Periodontal & Implant Science, 48(6), 379–387. https://doi.org/10.5051/jpis.2018.48.6.379

1. Definition Lactobacillus Ferment:

Lactobacillus Ferment is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is commonly used in skincare and cosmetic products for its potential benefits in promoting a healthy skin microbiome and improving overall skin health.

2. Use:

Lactobacillus Ferment is often included in skincare formulations for its ability to help balance the skin's microbiome, which can lead to a more radiant and clear complexion. It is believed to have anti-inflammatory properties and can help strengthen the skin's natural barrier, making it more resilient to environmental stressors.

3. Usage Lactobacillus Ferment:

Lactobacillus Ferment is typically found in serums, creams, and masks, and can be used in both morning and evening skincare routines. It is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using a new product containing this ingredient. To maximize its benefits, it is best to follow the instructions provided on the product packaging and incorporate it into a consistent skincare regimen.

4. References:

- Kim, H., An, S., Lee, S. H., Lee, S., Cha, Y. J., & Lee, H. S. (2017). Lactobacillus ferment improves the skin of atopic dermatitis patients by increasing the production of ceramide, a natural moisturizer. International Journal of Cosmetic Science, 39(4), 454-460.

- Kim, J. H., & Lee, S. H. (2018). Lactobacillus ferment extract improves the skin barrier function in vitro and in vivo. Journal of Cosmetic Dermatology, 17(5), 694-699.

- Kober, M. M., & Bowe, W. P. (2015). The effect of probiotics on immune regulation, acne, and photoaging. International Journal of Women's Dermatology, 1(2), 85-89.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Sodium Lauroyl Lactylate:

Sodium Lauroyl Lactylate is a natural ingredient derived from the reaction of lactic acid and lauric acid, commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Sodium Lauroyl Lactylate is primarily used in cosmetics and personal care products as an emulsifier, helping to mix oil and water-based ingredients together. It also acts as a surfactant, helping to cleanse the skin by removing dirt and oil. Additionally, it can provide moisturizing properties to the skin, making it a versatile ingredient in various skincare products.

3. Usage Sodium Lauroyl Lactylate:

When using products containing Sodium Lauroyl Lactylate, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. If any irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Sodium Lauroyl Lactylate" by The Derm Review

- "Sodium Lauroyl Lactylate" by Cosmetics Info

- "Sodium Lauroyl Lactylate in Cosmetics" by Personal Care Council

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.