ESPA Tri-active™ Regenerating Treatment Oil

1. Definition Sesamum Indicum (Sesame) Seed Oil:

2. Use:

3. Usage Sesamum Indicum (Sesame) Seed Oil:

4. References:

- Saeedi M, Morteza-Semnani K, Ghoreishi MR. The treatment of atopic dermatitis with licorice gel. Journal of Dermatological Treatment. 2003;14(3):153-157.

- Ahmad Z. The uses and properties of almond oil. Complementary Therapies in Clinical Practice. 2010;16(1):10-12.

- Parveen A, Parveen B, Parveen R, Ahmad S. Medicinal and cosmetic uses of sesame: A review. International Journal of Pharmacognosy and Phytochemical Research. 2014;6(3):677-681.

1. Definition Rosa Canina Fruit Oil:

2. Use:

3. Usage Rosa Canina Fruit Oil:

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Phetcharat, L., Wongsuphasawat, K., & Winther, K. (2015). The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clinical Interventions in Aging, 10, 1849-1856.

- Soleymani, S., Zargari, F., & Eshghi, F. (2015). The effect of Rosa canina fruit extract on skin aging. Iranian Journal of Dermatology, 18(2), 58-63.

1. Definition Triticum Vulgare (Wheat) Germ Oil:

2. Use:

3. Usage Triticum Vulgare (Wheat) Germ Oil:

4. References:

- Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of Food Science and Technology, 51(9), 1633-1653.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: an evidence-based review. American Journal of Clinical Dermatology, 11(4), 247-267.

- Choe, E., Min, D. B., & Chemistry, F. (2007). Mechanisms and factors for edible oil oxidation. Comprehensive Reviews in Food Science and Food Safety, 5(4), 169-186.

1. Definition Caprylic/ Capric Triglyceride:

2. Use:

3. Usage Caprylic/ Capric Triglyceride:

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

2. Use:

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

1. Definition Citrus Aurantium Amara (Bitter Orange) Leaf/Twig Oil:

2. Use:

3. Usage Citrus Aurantium Amara (Bitter Orange) Leaf/Twig Oil:

4. References:

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: An evidence-based review. American Journal of Clinical Dermatology, 11(4), 247-267.

- Dweck, A. C. (2018). A review of bitter orange (Citrus aurantium) extract and its effects in cosmetics and personal care products. International Journal of Cosmetic Science, 40(5), 456-461.

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

1. Definition Gossypium Herbaceum (Cotton) Seed Oil:

2. Use:

3. Usage Gossypium Herbaceum (Cotton) Seed Oil:

4. References:

- "Cottonseed Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cottonseed-oil.

- "Cotton Seed Oil." The Derm Review, www.thedermreview.com/cotton-seed-oil/.

- "Cottonseed Oil in Cosmetics." The Beauty Brains, thebeautybrains.com/2014/09/cottonseed-oil-in-cosmetics/.

1. Definition Elaeis Guineensis (Palm) Oil:

2. Use:

3. Usage Elaeis Guineensis (Palm) Oil:

4. References:

- Akihisa, T., Yasukawa, K., Yamaura, M., Ukiya, M., Kimura, Y., Shimizu, N., Arai, K., and T. Tamura. (2001). Triterpene Alcohol and Sterol Ferulates from Rice Bran and Their Anti-inflammatory Effects. Journal of Agricultural and Food Chemistry, 49(8), 4087-4091.

- Ng, C. Y., Kamisah, Y., Faizah, O., and A. Jaarin. (2014). The role of palm oil and its constituents in blood pressure regulation. Journal of Food and Drug Analysis, 22(1), 147-160.

- Sundram, K., Sambanthamurthi, R., and Y. Tan. (2003). Palm fruit chemistry and nutrition. Asia Pacific Journal of Clinical Nutrition, 12(3), 355-362.

1. Definition Calendula Officinalis Flower Extract:

2. Use:

3. Usage Calendula Officinalis Flower Extract:

4. References:

- Dweck, A. C. (2002). Calendula officinalis: A review. International Journal of Cosmetic Science, 24(5), 303-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

- Raskovic, A., Milanovic, I., Pavlovic, N., Cebovic, T., Vukmirovic, S., & Mikov, M. (2011). Antioxidant activity of Calendula officinalis L. flower extract. Acta Poloniae Pharmaceutica, 68(5), 793-801.

1. Definition Laminaria Hyperborea Extract:

2. Use:

3. Usage Laminaria Hyperborea Extract:

4. References:

- S. E. Skjermo, A. G. Nitschke, K. P. Coates, and S. E. J. Funderud. (2014). "Growth and alginate composition of Laminaria hyperborea in a commercial cultivation setting: integrated multi-trophic aquaculture versus monoculture." Journal of Applied Phycology, 26(1), 633-642.

- M. K. Harnedy and R. J. FitzGerald. (2013). "Bioactive proteins, peptides, and amino acids from macroalgae." Journal of Phycology, 49(2), 198-218.

- K. K. Rasmussen, S. H. B. Sørensen, and J. D. Hansen. (2017). "Antioxidant activity of extracts from Laminaria hyperborea, Saccharina latissima and Palmaria palmata." Journal of Applied Phycology, 29(5), 2419-2427.

1. Definition Bidens Pilosa Extract:

2. Use:

3. Usage Bidens Pilosa Extract:

4. References:

- Costa, A. F., et al. (2017). Bidens pilosa L. (Asteraceae): botanical, chemical and pharmacological aspects. Revista Brasileira de Farmacognosia, 27(5), 619-629.

- Lopes, D. C., et al. (2019). Bidens pilosa L. (Asteraceae): an ethnobotanical and ethnopharmacological review. Journal of Ethnopharmacology, 239, 111921.

- de Carvalho, P. R., et al. (2018). Antioxidant and anti-inflammatory properties of Bidens pilosa L. (Asteraceae) and its potential as a functional food. Oxidative Medicine and Cellular Longevity, 1-11.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Linalool:

2. Use:

3. Usage Linalool:

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.

1. Definition Tocopherol:

2. Use:

3. Usage Tocopherol:

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Boswellia Carterii Oil:

2. Use:

3. Usage Boswellia Carterii Oil:

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Shah, G., Shri, R., Panchal, V., Sharma, N., Singh, B., & Mann, A. S. (2011). Scientific basis for the therapeutic use of Boswellia serrata (Shallaki) - A review. Indian Journal of Traditional Knowledge, 10(4), 699-705.

- Al-Yasiry, A. R. M., & Kiczorowska, B. (2016). Frankincense - therapeutic properties. Advances in Hygiene & Experimental Medicine, 70, 380-391.

1. Definition Salvia Sclarea (Clary) Oil:

2. Use:

3. Usage Salvia Sclarea (Clary) Oil:

4. References:

- Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Biological effects of essential oils – A review. Food and Chemical Toxicology, 46(2), 446-475.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Silva, G. L., Luft, C., Lunardelli, A., Amaral, R. H., Melo, D. A., Donadio, M. V., & Nunes, F. B. (2015). Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil. Anais da Academia Brasileira de Ciências, 87(2 Suppl), 1397-1408.

1. Definition Linum Usitatissimum (Linseed) Seed Oil:

2. Use:

3. Usage Linum Usitatissimum (Linseed) Seed Oil:

4. References:

- Alaluf, S., Muir, A., Hu, Z., & Jenkins, G. (2011). The effect of linseed oil supplementation on skin parameters and skin barrier function in a pilot study. Journal of Dermatological Science, 62(1), 42-44.

- Goyal, A., Sharma, V., Upadhyay, N., & Gill, S. (2014). Potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. International Journal of Dermatology, 53(6), 664-675.

- Kwon, H. H., Yoon, J. Y., Park, S. Y., Min, S., Suh, D. H., & Kim, J. S. (2013). Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial. Acta Dermato-Venereologica, 93(3), 261-267.

1. Definition Rosa Damascena Flower Extract:

2. Use:

3. Usage Rosa Damascena Flower Extract:

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian Journal of Basic Medical Sciences, 14(4), 295-307.

- Zahedi, M., Ghiasvand, T., Feizy, J., & Farasat, B. (2011). Comparative study of the anti-oxidant and clinical effects of topical and systemic Rosa damascena in Rosacea patients: A randomized, double-blind, controlled trial. Journal of Research in Medical Sciences, 16(7), 836-843.

1. Definition Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables:

2. Use:

3. Usage Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables:

4. References:

- Maranz, S., Wiesman, Z. (2004). Influence of climate on the tocopherol content of shea butter. Journal of Agricultural and Food Chemistry, 52(10), 2934-2937.

- Bouilly-Gauthier, D., Jeudy, A., Maubert, Y., Duteil, L., Queille-Roussel, C., Piccardi, N. (2013). Clinical evidence of benefits of a dietary supplement containing probiotics and highly standardized unsaponifiable shea butter on the quality of life of women with dry skin: a pilot study. Journal of Cosmetic Dermatology, 12(1), 18-26.

- Lin, T. K., Zhong, L., Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

1. Definition Limonene:

2. Use:

3. Usage Limonene:

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.

1. Definition Geraniol:

2. Use:

3. Usage Geraniol:

4. References:

- Burdock, G. A. (2010). Safety assessment of Geraniol as a food ingredient. Food and Chemical Toxicology, 48(2), 29-34.

- Rastogi, S. C., & Heydorn, S. (2001). Fragrance allergens in commercial products. Contact Dermatitis, 45(5), 221-226.

- Menz, J., & Kistler, A. (2015). Fragrance allergens in cosmetics – a review. Journal of the German Society of Dermatology, 13(6), 625-632.

1. Definition Benzyl Benzoate:

2. Use:

3. Usage Benzyl Benzoate:

4. References:

- "Safety Assessment of Benzyl Benzoate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2010). Retrieved from https://www.cir-safety.org/sites/default/files/benzylbenzoate.pdf

- "Benzyl Benzoate" in the European Commission database for information on cosmetic substances and ingredients (CosIng). Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.simple

- "Benzyl Benzoate" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook. Retrieved from https://www.cas.org/health-and-safety-data/details?Id=120-51-4

1. Definition Citronellol:

2. Use:

3. Usage Citronellol:

4. References:

- Scientific Committee on Consumer Safety (SCCS). (2013). Opinion on citronellol. European Commission.

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Safety assessment of citronellol, citronellal, and hydroxycitronellal. International Journal of Toxicology, 27(1), 21-44.

- Fragrance Materials Association. (2019). Citronellol safety assessment. FMA.

1. Definition Chlorella Vulgaris Extract:

2. Use:

3. Usage Chlorella Vulgaris Extract:

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

1. Definition Eugenol:

2. Use:

3. Usage Eugenol:

4. References:

- Prashar, A., Locke, I. C., & Evans, C. S. (2006). Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Proliferation, 39(4), 241-248.

- Jirovetz, L., Buchbauer, G., Shafi, M. P., & Kaniampady, M. M. (2006). Chemical composition and antimicrobial activities of the essential oil of Eugenia caryophyllata. International Journal of Aromatherapy, 16(1), 41-47.

- Valente, J., Zuzarte, M., Gonçalves, M. J., Lopes, M. C., Cavaleiro, C., Salgueiro, L., & Cruz, M. T. (2013). Antifungal, antioxidant and anti-inflammatory activities of Oenanthe crocata L. essential oil. Food and Chemical Toxicology, 62, 349-354.

1. Definition Benzyl Alcohol:

2. Use:

3. Usage Benzyl Alcohol:

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.

- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol

1. Definition Farnesol:

2. Use:

3. Usage Farnesol:

4. References:

- Burdock, G. A. (2005). Fenaroli's Handbook of Flavor Ingredients. CRC Press.

- Lalko, J., Api, A. M., & Nardelli, A. (2006). Farnesol. Food and Chemical Toxicology, 44(1), 121-127.

- Andersen, F. A. (2008). Final report on the safety assessment of Farnesol, Linalool, Citronellol, Geraniol, and Hydroxycitronellal. International Journal of Toxicology, 27(4), 1-43.