Facis Cream With Azulene

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Sorbitan Stearate:

Sorbitan stearate is a type of emulsifier commonly used in cosmetics and personal care products. It is derived from sorbitol, a sugar alcohol, and stearic acid, a fatty acid. Sorbitan stearate helps to mix oil and water-based ingredients in formulations, creating stable emulsions.

2. Use:

Sorbitan stearate is used in a wide range of cosmetics and personal care products, such as creams, lotions, sunscreens, and makeup. It helps to stabilize the emulsion, prevent separation of ingredients, and improve the texture and feel of the product. Sorbitan stearate also acts as a surfactant, helping to cleanse the skin by removing dirt and oil.

3. Usage Sorbitan Stearate:

When using products containing sorbitan stearate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with sorbitan stearate to ensure they do not have an adverse reaction. Additionally, it is recommended to avoid getting sorbitan stearate in the eyes or mouth, and to discontinue use if any irritation occurs.

4. References:

- "Sorbitan Stearate" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/sorbitan-stearate

- "Sorbitan Stearate" Truth in Aging, https://www.truthinaging.com/ingredients/sorbitan-stearate

- "Sorbitan Stearate" The Derm Review, https://thedermreview.com/sorbitan-stearate/

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition 1,2 Hexanediol:

1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.

2. Use:

1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.

3. Usage 1,2 Hexanediol:

When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.

Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.

4. References:

- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook

- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.

1. Definition Sorbitan Sesquioleate:

Sorbitan Sesquioleate is an emulsifier derived from sorbitol and oleic acid. It is commonly used in cosmetics and personal care products to help mix oil and water-based ingredients together.

2. Use:

Sorbitan Sesquioleate is primarily used as an emulsifier in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to stabilize the mixture of oil and water-based ingredients, ensuring a smooth and uniform texture.

3. Usage Sorbitan Sesquioleate:

When using Sorbitan Sesquioleate in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient may lead to skin irritation or sensitization in some individuals. It is also essential to conduct a patch test before using products containing Sorbitan Sesquioleate, especially if you have sensitive skin.

4. References:

- "Sorbitan Sesquioleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sorbitan-sesquioleate.

- "Sorbitan Sesquioleate." The Derm Review, www.thedermreview.com/sorbitan-sesquioleate/.

- "Sorbitan Sesquioleate." Truth In Aging, www.truthinaging.com/ingredients/sorbitan-sesquioleate.

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition CI 42090:

CI 42090, also known as Blue 1, is a synthetic dye commonly used in cosmetics to impart a blue color to various products.

2. Use:

CI 42090 is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often found in products such as shampoos, conditioners, body washes, lotions, and eyeshadows to provide a vibrant blue hue.

3. Usage CI 42090:

When using cosmetics containing CI 42090, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using the product to check for any allergic reactions or sensitivities. Additionally, CI 42090 may stain clothing and fabrics, so it is advisable to be cautious when applying the product.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Blue 1." International Journal of Toxicology, 2008.

- "Safety assessment of CI 42090." Cosmetic Ingredient Review, 2009.

- "Blue 1." Personal Care Council, accessed March 2021.

1. Definition CI 60730:

CI 60730, also known as Ext. D&C Violet 2, is a synthetic colorant commonly used in cosmetics to provide a purple or violet hue to various products.

2. Use:

CI 60730 is primarily used in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes to add a vibrant purple color to the products. It is also commonly used in hair dyes to achieve shades of purple or violet.

3. Usage CI 60730:

When using cosmetics containing CI 60730, it is important to follow the manufacturer's instructions and guidelines for application. It is recommended to perform a patch test before using the product to check for any allergic reactions or sensitivities. Avoid direct contact with the eyes and mucous membranes, and discontinue use if any irritation occurs.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Ext. D&C Violet No. 2. International Journal of Toxicology, 27(1), 1-21.

- Food and Drug Administration. (2018). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics

- European Commission. (2019). CosIng - Cosmetic Ingredients Database. Retrieved from https://ec.europa.eu/growth/sectors/cosmetics/cosing_en

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

1. Definition Persea Gratissima (Avocado) Oil:

Persea Gratissima (Avocado) Oil is a natural oil extracted from the avocado fruit. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Avocado oil is known for its moisturizing and nourishing properties, making it a great ingredient for hydrating dry and damaged skin. It is also believed to have anti-inflammatory and antioxidant properties, which can help soothe irritated skin and protect it from environmental stressors. In haircare products, avocado oil is used to condition and strengthen hair, leaving it soft and shiny.

3. Usage Persea Gratissima (Avocado) Oil:

Avocado oil can be used in various ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums for added hydration. In haircare products, it can be used in hair masks, conditioners, and styling products to nourish and protect the hair. It is generally safe for all skin types, but individuals with avocado allergies should avoid using products containing avocado oil.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Lorraine Dallmeier. (2016). "A Comprehensive Guide to Essential Oils." CreateSpace Independent Publishing Platform.

- R. Ranade, R. Nash, R. Dr. (2010). "Handbook of Cosmetic Science and Technology." Informa Healthcare.

1. Definition Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is a natural ingredient derived from the root of the Rehmannia glutinosa plant, which is native to East Asia. This extract is known for its anti-inflammatory, antioxidant, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Rehmannia Glutinosa Root Extract is commonly used in cosmetics for its ability to soothe and hydrate the skin. It can help reduce redness, inflammation, and irritation, making it ideal for sensitive or dry skin types. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is typically found in creams, serums, and masks. It can be applied directly to the skin as part of a skincare routine, either on its own or in combination with other ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using the extract to ensure compatibility with your skin.

4. References:

- Kim, S. H., Kim, S. H., Park, S., & Lee, J. H. (2018). Anti-Inflammatory Effects of Rehmannia glutinosa Libosch Extract in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Nutrients, 10(10), 1531.

- Choi, H. J., Chung, T. W., Park, M. J., & Choi, H. J. (2017). Rehmannia glutinosa Libosch extracts inhibits inflammatory responses and joint destruction in collagen-induced arthritic mice. Journal of Ethnopharmacology, 196, 126-132.

- Lee, S., Kim, M. G., Ko, Y. S., Lee, J. H., & Kim, H. K. (2020). Anti-inflammatory effects of Rehmannia glutinosa Libosch extracts on LPS-stimulated RAW 264.7 cells. Journal of Microbiology and Biotechnology, 30(3), 429-437.

1. Definition Prunus Mume Fruit Extract:

Prunus Mume Fruit Extract is derived from the Japanese apricot tree, also known as Ume or Plum Blossom. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Prunus Mume Fruit Extract is used in cosmetics for its anti-aging and brightening properties. It helps to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has hydrating and soothing effects on the skin, making it suitable for all skin types.

3. Usage Prunus Mume Fruit Extract:

Prunus Mume Fruit Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and is safe for daily use. To incorporate this ingredient into your skincare routine, look for products that list Prunus Mume Fruit Extract as one of the main ingredients.

4. References:

- Kim, H. J., Kim, S. H., & Yun, J. M. (2018). Anti-wrinkle and skin-whitening effects of Prunus mume fruit extract. Journal of Cosmetic Dermatology, 17(2), 219-224.

- Lee, H. J., Lee, J. H., & Kim, H. S. (2016). Antioxidant and anti-inflammatory effects of Prunus mume extract on UVB-induced damage in HaCaT keratinocytes. Journal of Cosmetic Science, 67(3), 179-186.

- Park, S. Y., Kim, D. S., & Park, Y. H. (2014). Skin brightening effects of Prunus mume extract in human volunteers. International Journal of Cosmetic Science, 36(6), 588-593.

1. Definition Schizonepeta Tenuifolia Extract:

Schizonepeta Tenuifolia Extract is derived from the Schizonepeta plant, which is native to East Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Schizonepeta Tenuifolia Extract is often used in cosmetics for its soothing and calming effects on the skin. It can help reduce redness, irritation, and inflammation, making it a popular ingredient in products targeted towards sensitive or acne-prone skin. Additionally, it has been shown to have antimicrobial properties, making it effective in fighting off acne-causing bacteria.

3. Usage Schizonepeta Tenuifolia Extract:

Schizonepeta Tenuifolia Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in small concentrations and is safe for most skin types. However, as with any new ingredient, it is recommended to do a patch test before applying it to the entire face to ensure there are no adverse reactions. It is best to follow the instructions on the product packaging for the recommended usage.

4. References:

- Kim, M. J., Kim, H. K., & Cho, H. Y. (2016). Anti-inflammatory effects of Schizonepeta tenuifolia through the suppression of nuclear factor-κB and mitogen-activated protein kinases signaling pathways in LPS-induced RAW 264.7 macrophages. Journal of Bacteriology and Virology, 46(3), 209-217.

- Kim, S. H., Kim, S. H., Kim, Y. S., & Jeong, Y. J. (2014). Anti-inflammatory effect of Schizonepeta tenuifolia through the inhibition of the nuclear factor-κB signaling pathway in LPS-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 65, 70-75.

- Kim, M. J., Kim, H. K., & Cho, H. Y. (2017). Inhibitory effects of Schizonepeta tenuifolia extract on atopic dermatitis-like skin lesions in NC/Nga mice. Journal of Ethnopharmacology, 206, 156-163.

1. Definition Saururus Chinensis Leaf/Root Extract:

Saururus Chinensis Leaf/Root Extract is a botanical extract derived from the leaves and roots of the Saururus Chinensis plant. This plant is native to East Asia and has been used in traditional medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Saururus Chinensis Leaf/Root Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It is known to help reduce inflammation, improve skin texture, and protect against environmental stressors. This extract is often included in skincare products such as serums, creams, and masks to promote healthier and more radiant skin.

3. Usage Saururus Chinensis Leaf/Root Extract:

When using cosmetics containing Saururus Chinensis Leaf/Root Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean skin, avoiding contact with the eyes. Perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Lee, S., Kim, K., Kim, J., Kim, Y., & Lee, J. (2019). Anti-inflammatory effect of Saururus chinensis extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Molecular Medicine Reports, 19(1), 635-642.

- Choi, J., Kim, H., Kim, H., & Kim, S. (2017). Protective effects of Saururus chinensis extract on UVB-induced damage in human keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 173, 58-63.

- Park, J., Kim, S., Kim, J., Kim, J., & Lee, C. (2016). Anti-aging effects of Saururus chinensis extract in human dermal fibroblasts. Journal of Cosmetic Dermatology, 15(4), 445-451.

1. Definition Polygonum Fagopyrum Seed Extract:

Polygonum Fagopyrum Seed Extract, also known as buckwheat seed extract, is derived from the seeds of the buckwheat plant. It is rich in antioxidants, vitamins, and minerals that offer various benefits for the skin.

2. Use:

Polygonum Fagopyrum Seed Extract is commonly used in cosmetics for its anti-aging, anti-inflammatory, and skin-soothing properties. It helps to protect the skin from environmental stressors, improve skin elasticity, and promote a more youthful appearance.

3. Usage Polygonum Fagopyrum Seed Extract:

Polygonum Fagopyrum Seed Extract can be found in a wide range of skincare products, including serums, creams, and masks. It is typically used as an active ingredient to target specific skin concerns such as fine lines, wrinkles, and redness. To use, apply the product containing the extract onto clean skin and gently massage in until fully absorbed.

Precautions: While Polygonum Fagopyrum Seed Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying it to the entire face. If any irritation or allergic reaction occurs, discontinue use immediately. It is also important to follow the instructions provided on the product packaging for optimal results.

4. References:

- Kim, M. J., Kim, H. K., & Kim, J. H. (2011). Anti-inflammatory effect of buckwheat (Fagopyrum esculentum Moench) sprouts. Journal of the Science of Food and Agriculture, 91(4), 623-629.

- Song, J. E., Kim, M. J., & Kim, J. H. (2015). Protective effect of buckwheat (Fagopyrum esculentum Moench) against lipopolysaccharide-induced acute lung injury in mice. Journal of Functional Foods, 19, 111-121.

- Kim, M. J., Kim, H. K., & Kim, J. H. (2011). Buckwheat (Fagopyrum esculentum Moench) sprout extract protects against hydrogen peroxide-induced cell death in human SH-SY5Y neuroblastoma cells. Journal of Medicinal Food, 14(11), 1360-1369.

1. Definition Glycine Soja (Soybean) Seed Extract:

Glycine Soja (Soybean) Seed Extract is an extract derived from soybean seeds, rich in proteins, amino acids, and antioxidants. It is commonly used in skincare and cosmetic products for its moisturizing, anti-aging, and skin-brightening properties.

2. Use:

Glycine Soja (Soybean) Seed Extract is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It is often included in anti-aging products, such as serums, creams, and masks, to help boost collagen production and improve skin elasticity.

3. Usage Glycine Soja (Soybean) Seed Extract:

When using products containing Glycine Soja (Soybean) Seed Extract, it is important to patch test first to check for any potential allergic reactions or sensitivities. To incorporate this ingredient into your skincare routine, apply a small amount of the product to a small area of skin and wait 24 hours to see if any irritation occurs. If no adverse reactions occur, you can continue to use the product as directed.

4. References:

- Kim, S. Y., & Kim, J. K. (2016). Anti-aging effects of soy extract on human fibroblasts. Journal of Cosmetic Dermatology, 15(3), 305-313.

- Jung, E. M., An, B. S., Choi, J. H., & Jeung, E. B. (2014). Potential estrogenic activity of soy isoflavones and their metabolites depends on the specific source of soybean. Journal of Medicinal Food, 17(2), 254-261.

- Lee, S. H., Lee, J. H., Kim, Y. S., Jeong, G. J., Lee, J. H., An, S. M., & Kim, Y. C. (2017). Skin protective effect of soy extract against UVB-induced skin aging in vitro and in vivo. Journal of Functional Foods, 31, 1-10.

1. Definition Acanthopanax Senticosus (Eleuthero) Root Extract:

Acanthopanax Senticosus (Eleuthero) Root Extract is a natural ingredient derived from the roots of the Eleuthero plant, also known as Siberian ginseng. It is known for its adaptogenic properties and is commonly used in skincare products for its antioxidant and anti-inflammatory benefits.

2. Use:

Acanthopanax Senticosus Root Extract is used in cosmetics for its ability to help protect the skin from environmental stressors, improve skin texture, and promote overall skin health. It is often included in anti-aging products to help reduce the appearance of fine lines and wrinkles, as well as in products designed to soothe and calm sensitive or irritated skin.

3. Usage Acanthopanax Senticosus (Eleuthero) Root Extract:

Acanthopanax Senticosus Root Extract can be found in a variety of skincare products, including serums, creams, masks, and lotions. It is typically used in concentrations ranging from 0.5% to 2% and is suitable for all skin types. To incorporate this ingredient into your skincare routine, simply apply products containing Acanthopanax Senticosus Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee, S., Shin, E., Lee, J., Kim, J., Kim, Y., & Kim, Y. (2016). Protective effect of Acanthopanax senticosus stem extract on UVB-induced damage in HaCaT cells. Journal of Photochemistry and Photobiology B: Biology, 159, 22-30.

- Kim, J., Kim, Y., Kim, J., & Lee, J. (2017). Anti-inflammatory effect of Acanthopanax senticosus extract in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of Ethnopharmacology, 196, 58-66.

- Kim, J., Kim, Y., Kim, J., & Lee, J. (2018). Acanthopanax senticosus stem extract alleviates skin photoaging in UVB-irradiated human dermal fibroblasts and C57BL/6J mice. Journal of Dermatological Science, 89(3), 239-248.

1. Definition Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is an extract derived from the root of the Ulmus Davidiana tree, also known as the David Elm. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Ulmus Davidiana Root Extract is commonly used in cosmetics for its various skin benefits. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, this extract can help improve skin tone and texture, resulting in a more radiant and youthful complexion.

3. Usage Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. As with any new skincare ingredient, it is important to perform a patch test before using it on the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Lee, Y. H., Kim, J. H., Song, M. Y., & Park, S. Y. (2015). Antioxidant and anti-inflammatory activities of the ethanolic extract of Ulmus davidiana var. japonica. Journal of Life Science, 25(2), 177-183.

- Kim, J. Y., Kim, H. J., Kim, O. Y., & Lee, J. H. (2016). Anti-inflammatory effects of Ulmus davidiana var. japonica in RAW 264.7 cells. Journal of Life Science, 26(8), 904-911.

- Park, S. Y., Lee, Y. H., Kim, J. H., & Song, M. Y. (2017). Skin-brightening effects of Ulmus davidiana var. japonica extract in human skin cells. Journal of Cosmetic Science, 68(3), 185-192.

1. Definition Smilax Glabra Root Extract:

Smilax Glabra Root Extract is a natural ingredient derived from the root of the Chinese herb Smilax Glabra, also known as China Root or Tu Fu Ling. It is commonly used in traditional Chinese medicine for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Smilax Glabra Root Extract is often included in cosmetic formulations for its ability to help calm and nourish the skin. It is known to help reduce redness, irritation, and inflammation, making it a popular ingredient in products targeted towards sensitive or acne-prone skin. Additionally, its antioxidant properties can help protect the skin from environmental stressors and signs of aging.

3. Usage Smilax Glabra Root Extract:

Smilax Glabra Root Extract can be found in various skincare products such as serums, creams, masks, and toners. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing this extract, apply a small amount onto clean skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using to check for any potential allergic reactions.

4. References:

- Chen, X., Liu, J., Guo, J., Su, J., & Zhang, X. (2018). Chemical constituents from Smilax glabra Roxb. Fitoterapia, 125, 48-54.

- Zhang, J., Wang, Y., & Zhang, X. (2017). Anti-inflammatory effect of Smilax glabra Roxb. extract on acute and chronic dermatitis models. Journal of Ethnopharmacology, 207, 47-56.

- Wang, Y., Zhang, J., & Zhang, X. (2016). Antioxidant and anti-inflammatory activities of Smilax glabra extract and its major polyphenolic compounds. Molecules, 21(9), 1173.

1. Definition Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract is derived from the leaves of the Ginkgo Biloba tree, a plant native to China. It is known for its antioxidant properties and is commonly used in skincare products for its potential benefits in improving skin texture and reducing signs of aging.

2. Use:

Ginkgo Biloba Leaf Extract is often included in cosmetic formulations for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental stressors, such as pollution and UV radiation, and promote overall skin health. Additionally, Ginkgo Biloba Leaf Extract may help improve circulation and promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting aging, dullness, and uneven skin tone. To incorporate Ginkgo Biloba Leaf Extract into your skincare routine, look for products specifically formulated with this ingredient and follow the instructions provided by the manufacturer.

4. References:

- Choi, H. S., Kim, M. K., Lee, K., Lee, K. M., Kim, Y. J., & Jun, W. (2017). Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells. Journal of medicinal food, 20(6), 579-586.

- Zhou, L., Gao, Q., Zhang, G., Wang, X., Zhang, J., & Zhang, L. (2018). Ginkgo biloba extract inhibits astrocytic lipocalin‐2 expression and alleviates neuroinflammatory injury via the JAK2/STAT3 pathway after ischemic brain stroke. Phytotherapy Research, 32(12), 2527-2536.

- Kaur, N., Kishore, L., Singh, R., & Singh, S. (2018). Ginkgo biloba: A potential natural product in the treatment of metabolic syndrome. Pharmacognosy reviews, 12(23), 111.

1. Definition Prunus Armeniaca (Apricot) Kernel Extract:

Prunus Armeniaca (Apricot) Kernel Extract is a natural ingredient derived from the kernels of apricot fruit. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular choice in skincare products.

2. Use:

Prunus Armeniaca (Apricot) Kernel Extract is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. Additionally, it has soothing and anti-inflammatory benefits, making it suitable for sensitive or irritated skin.

3. Usage Prunus Armeniaca (Apricot) Kernel Extract:

Prunus Armeniaca (Apricot) Kernel Extract can be found in various skincare products such as moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing this extract, it is important to patch test first to check for any potential allergic reactions. It is also recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Kim, M. J., Yoon, J. H., Kim, J. H., & Kim, S. Y. (2013). Anti-inflammatory effects of Prunus armeniaca L. on contact dermatitis induced by dinitrofluorobenzene in mice. Experimental and therapeutic medicine, 5(2), 523-528.

- Park, S. Y., Kim, Y. H., Park, G., & Kim, J. H. (2015). Anti-aging effects of Prunus armeniaca L. extract on UVB-induced wrinkle formation in hairless mice. Journal of the Korean Society of Cosmetology, 21(3), 359-366.

- Lee, S. H., Kim, Y. H., & Kim, J. H. (2018). Moisturizing effects of Prunus armeniaca L. extract on human skin. Journal of the Society of Cosmetic Scientists of Korea, 44(4), 271-277.

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Sanguisorba Officinalis Root Extract:

Sanguisorba Officinalis Root Extract, also known as Great Burnet Root Extract, is a natural ingredient derived from the root of the Sanguisorba Officinalis plant. This plant is native to Europe and Asia and has been used in traditional medicine for its anti-inflammatory and astringent properties.

2. Use:

Sanguisorba Officinalis Root Extract is commonly used in cosmetics for its skin-soothing and anti-inflammatory benefits. It is known to help reduce redness, calm irritated skin, and promote overall skin health. This extract is often included in products targeting sensitive or acne-prone skin, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Sanguisorba Officinalis Root Extract:

Sanguisorba Officinalis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used at concentrations ranging from 0.1% to 2% in formulations. When using products containing this extract, it is important to patch test first to check for any potential allergic reactions. It is also recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Kim, M. J., Kim, H. J., Kim, D. H., Lee, Y. M., & Kim, H. K. (2008). Anti-inflammatory activity of constituents from Sanguisorba officinalis. Phytotherapy Research, 22(5), 705-709.

- Lee, J. H., & Kim, G. H. (2008). Anti-inflammatory effect of Sanguisorba officinalis L. extract on contact dermatitis in mice. Journal of Ethnopharmacology, 116(3), 532-537.

- Park, C. H., Choi, S. H., Lee, Y. S., Hwang, H. J., & Kim, G. Y. (2018). Anti-inflammatory effects of Sanguisorba officinalis L. on contact dermatitis induced by dinitrofluorobenzene in mice. Journal of Ethnopharmacology, 222, 118-124.

1. Definition Phellodendron Amurense Bark Extract:

Phellodendron Amurense Bark Extract is derived from the bark of the Amur cork tree, a species native to eastern Asia. This extract is known for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a popular ingredient in skincare products.

2. Use:

Phellodendron Amurense Bark Extract is commonly used in cosmetics for its ability to soothe and calm irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is often included in products targeted towards sensitive or acne-prone skin, as well as anti-aging formulations.

3. Usage Phellodendron Amurense Bark Extract:

When using products containing Phellodendron Amurense Bark Extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a small amount and gradually increase usage to assess tolerance. This extract can be found in a variety of skincare products, including serums, creams, and masks, and should be applied as directed by the manufacturer.

4. References:

- Kim, J., Kim, H., Kim, J., Kim, M., & Kim, H. (2013). Anti-inflammatory effect of Phellodendron amurense in peripheral blood mononuclear cells from patients with Behçet's disease. Phytotherapy Research, 27(3), 370-375.

- Park, S., Kim, J., Kim, H., Kim, J., & Kim, H. (2015). Antimicrobial activity of Phellodendron amurense against acne-causing bacteria. Journal of Cosmetic Dermatology, 14(1), 32-37.

- Lee, S., Lee, J., Kang, S., Kim, J., & Kim, H. (2017). Antioxidant properties of Phellodendron amurense bark extract and its potential application in skincare products. Journal of Dermatological Science, 85(3), 186-191.

1. Definition Zanthoxylum Piperitum Fruit Extract:

Zanthoxylum Piperitum Fruit Extract, also known as Japanese Pepper Extract, is derived from the fruit of the Zanthoxylum piperitum plant. This extract is known for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Zanthoxylum Piperitum Fruit Extract is commonly used in cosmetics for its ability to soothe irritated skin, reduce redness, and fight against free radicals that can cause premature aging. It is often found in skincare products such as serums, lotions, and creams targeting sensitive or acne-prone skin.

3. Usage Zanthoxylum Piperitum Fruit Extract:

When using products containing Zanthoxylum Piperitum Fruit Extract, it is important to patch test first to ensure there is no allergic reaction. It is recommended to start with a small amount of product and gradually increase usage if no adverse effects are observed. This extract is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before incorporating it into their skincare routine.

4. References:

- Kim, J. Y., et al. (2017). Anti-inflammatory effects of Zanthoxylum piperitum in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 203, 306-314.

- Lee, H. S., et al. (2015). Anti-inflammatory effects of Zanthoxylum piperitum ethanol extract in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Journal of Medicinal Food, 18(3), 294-303.

- Park, H. J., et al. (2011). Antimicrobial activity of Zanthoxylum piperitum ethanol extract against Propionibacterium acnes. Journal of Microbiology, 49(4), 686-691.

1. Definition Pinus Sylvestris Bark Extract:

Pinus Sylvestris Bark Extract is derived from the bark of the Scots Pine tree, scientifically known as Pinus Sylvestris. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Pinus Sylvestris Bark Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and anti-aging properties. It helps to protect the skin from environmental damage, reduce redness and irritation, and promote collagen production for firmer, more youthful-looking skin.

3. Usage Pinus Sylvestris Bark Extract:

When using skincare products containing Pinus Sylvestris Bark Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but a patch test is recommended before using it on the entire face to check for any potential allergic reactions. Avoid contact with the eyes and discontinue use if any irritation occurs.

4. References:

- Lee, J. H., Kim, M. H., Lee, N. H., & Kim, K. T. (2014). Anti-inflammatory and anti-aging effects of Pinus densiflora bark extract in human fibroblasts and keratinocytes. Journal of Ethnopharmacology, 153(2), 409-415.

- Kwon, Y. S., Kim, K. T., & Kim, M. H. (2017). Antioxidant and anti-inflammatory effects of Pinus densiflora bark extract in RAW 264.7 macrophages. Journal of Medicinal Food, 20(7), 678-685.

- Park, J. S., Kim, K. T., & Kim, M. H. (2016). Anti-aging effects of Pinus densiflora bark extract in UVB-irradiated human dermal fibroblasts. Journal of Cosmetic Science, 67(1), 1-10.

1. Definition Portulaca Oleracea Extract:

Portulaca Oleracea Extract is a natural ingredient derived from the common purslane plant, known for its high levels of antioxidants, omega-3 fatty acids, vitamins, and minerals. It has been used for centuries in traditional medicine for its anti-inflammatory, antimicrobial, and healing properties.

2. Use:

Portulaca Oleracea Extract is commonly used in cosmetics for its soothing and nourishing benefits on the skin. It is known to help reduce redness, irritation, and inflammation, making it ideal for sensitive or acne-prone skin. Additionally, its antioxidant properties help protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Portulaca Oleracea Extract:

Portulaca Oleracea Extract can be found in a variety of skincare products, such as serums, moisturizers, masks, and creams. It is typically included in formulations at a concentration of 0.5-2% to provide the desired benefits without causing any irritation. To use products containing Portulaca Oleracea Extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Kim, M. J., Kim, H. K., Anti-inflammatory effect of Portulaca oleracea in LPS-stimulated RAW 264.7 macrophages. The American Journal of Chinese Medicine. 2014; 42(6):1493-1507.

- Choi, J. H., Kim, D. W., Park, S. E., et al. Protective effect of Portulaca oleracea extracts on DSS-induced murine colitis. International Immunopharmacology. 2019; 73:539-547.

- Lee, H. Y., Kim, S. W., Lee, G. H., et al. The effect of Portulaca oleracea extracts on UVB-induced photoaging in human skin fibroblasts. Journal of Ethnopharmacology. 2018; 220:64-73.

1. Definition Magnolia Obovata Bark Extract:

Magnolia Obovata Bark Extract is a natural ingredient derived from the bark of the Magnolia obovata tree. This extract is rich in bioactive compounds such as honokiol and magnolol, which have antioxidant and anti-inflammatory properties.

2. Use:

Magnolia Obovata Bark Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce redness, inflammation, and irritation, making it ideal for sensitive or reactive skin types. Additionally, the antioxidant properties of this extract can help protect the skin from environmental stressors and premature aging.

3. Usage Magnolia Obovata Bark Extract:

Magnolia Obovata Bark Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, apply products containing Magnolia Obovata Bark Extract after cleansing and toning, and follow with a moisturizer.

4. References:

- Kim, S. J., Kim, J. S., Cho, H. S., Lee, J. H., Kim, Y. J., Lee, S. R., & Kim, Y. C. (2009). Honokiol inhibits oxidative stress-induced inflammatory responses in rat aortic smooth muscle cells. Toxicology and applied pharmacology, 237(2), 171-180.

- Choi, H. S., Kim, S. L., Kim, J. H., Jeong, S. I., Kim, S. H., & Kim, S. J. (2013). Anti-inflammatory and anti-aging effects of magnolia bark extract on human skin cells. International journal of cosmetic science, 35(4), 376-381.

- Lee, J. H., Kim, Y. G., Ra, J. C., Ko, S. H., & Choi, I. G. (2017). Anti-inflammatory effect of magnolia bark extract in human keratinocytes. International journal of molecular sciences, 18(10), 2147.

1. Definition Polygonum Cuspidatum Root Extract:

Polygonum Cuspidatum Root Extract, also known as Japanese Knotweed extract, is a natural ingredient derived from the root of the Polygonum cuspidatum plant. It is rich in antioxidants, particularly resveratrol, which has anti-inflammatory and anti-aging properties.

2. Use:

Polygonum Cuspidatum Root Extract is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It helps to protect the skin from environmental damage, reduce redness and inflammation, and promote a more youthful complexion. It is often found in anti-aging serums, moisturizers, and treatments targeting skin concerns such as fine lines, wrinkles, and uneven skin tone.

3. Usage Polygonum Cuspidatum Root Extract:

When using products containing Polygonum Cuspidatum Root Extract, it is important to follow the manufacturer's instructions for application. Typically, the extract is incorporated into skincare products at a concentration of 1-5%. It is generally safe for most skin types, but as with any new ingredient, it is recommended to perform a patch test before regular use to check for any potential sensitivities or allergic reactions.

4. References:

- Shin, J. W., Wang, J. H., Kang, J. K., Son, C. G., & Kim, H. J. (2019). Anti-inflammatory effect of Polygonum cuspidatum in patients with knee osteoarthritis. The American Journal of Chinese Medicine, 47(7), 1557-1570.

- Park, H. J., Jung, H. J., Kwon, H. J., Kim, K. A., Lim, S. S., & Kwak, J. H. (2012). Antioxidant activity and cell protective effect of Polygonum cuspidatum root extract. Korean Journal of Food Science and Technology, 44(5), 559-564.

- Lee, H. J., Lee, H. J., Lim, E. J., & Lee, E. O. (2017). Polygonum cuspidatum extract attenuates inflammatory responses in a murine model of lipopolysaccharide-induced acute lung injury. Journal of Ethnopharmacology, 206, 124-130.

1. Definition Sophora Angustifolia Root Extract:

Sophora Angustifolia Root Extract is a natural extract derived from the roots of the Sophora Angustifolia plant. This plant is known for its medicinal properties and has been used in traditional Chinese medicine for centuries.

2. Use:

Sophora Angustifolia Root Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-brightening properties. It is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Sophora Angustifolia Root Extract:

When using products containing Sophora Angustifolia Root Extract, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this extract.

4. References:

- Kim, S. H., Kim, H. J., Kim, Y. H., Jeong, S. J., Kim, Y. S., & Lim, D. S. (2012). Anti-inflammatory activity of compounds from the root of Sophora flavescens. Journal of ethnopharmacology, 143(3), 867-871.

- Lee, H. J., Lee, J. H., Lee, J. H., Kim, M. H., Yang, H. J., Kim, H. J., ... & Kim, J. Y. (2018). Anti-inflammatory effect of Sophora flavescens Aiton in a mouse model of phthalic anhydride-induced atopic dermatitis. Experimental and therapeutic medicine, 15(2), 1578-1584.

- Park, G. H., Song, H. M., Jeong, J. B., Hong, E. H., Chang, M., Park, J. H., ... & Lee, H. S. (2016). The root extract of Sophora flavescens enhances anti-adipogenic effect of platycodin D, a major component of Platycodon grandiflorum. Journal of ethnopharmacology, 194, 95-103.

1. Definition Ganoderma Lucidum (Mushroom) Stem Extract:

Ganoderma Lucidum (Mushroom) Stem Extract is a natural ingredient derived from the stem of the Ganoderma Lucidum mushroom, also known as the Reishi mushroom. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Ganoderma Lucidum (Mushroom) Stem Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This extract also has anti-inflammatory and anti-bacterial properties, making it effective in treating acne and other skin conditions.

3. Usage Ganoderma Lucidum (Mushroom) Stem Extract:

Ganoderma Lucidum (Mushroom) Stem Extract can be found in a variety of skincare products, including serums, creams, and masks. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with this extract regularly for best results.

4. References:

- Kim, H.G., Shrestha, B., Lim, S.Y., Yoon, D.H., Chang, W.C., Shin, D.J., & Shin, Y.S. (2011). Antioxidant and immunostimulating activities of the fruiting bodies of Ganoderma applanatum. Journal of Microbiology and Biotechnology, 21(9), 945-954.

- Lindequist, U., Niedermeyer, T.H., & Jülich, W.D. (2005). The pharmacological potential of mushrooms. Evidence-based Complementary and Alternative Medicine, 2(3), 285-299.

- Chen, Y., Zhang, Y., & Feng, K. (2012). The pharmacological potential of Ganoderma lucidum. Evidence-based Complementary and Alternative Medicine, 2012, 1-12.

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Oryza Sativa (Rice) Bran Extract:

Oryza Sativa (Rice) Bran Extract is a natural ingredient derived from the outer layer of rice grains. It is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare products.

2. Use:

Oryza Sativa (Rice) Bran Extract is commonly used in cosmetics for its skin-soothing and brightening properties. It helps to improve skin tone, reduce inflammation, and protect the skin from environmental damage. Additionally, it has moisturizing properties that can help hydrate and nourish the skin.

3. Usage Oryza Sativa (Rice) Bran Extract:

Oryza Sativa (Rice) Bran Extract can be found in a variety of skincare products such as serums, moisturizers, masks, and cleansers. It is typically used in concentrations ranging from 0.1% to 5% in formulations. To incorporate it into your skincare routine, look for products that list Oryza Sativa (Rice) Bran Extract as one of the main ingredients.

Precautions: While Oryza Sativa (Rice) Bran Extract is generally considered safe for use in cosmetics, it is always recommended to do a patch test before trying a new product to ensure you do not have any allergic reactions. If you have sensitive skin or any known allergies, consult with a dermatologist before using products containing this ingredient.

4. References:

- Kusumawati, D., et al. (2017). Antioxidant Activity of Rice Bran Extract and Its Effect on Shelf Life of Beef Sausage. International Journal of Food Science, 2017.

- Kim, J. M., et al. (2018). Anti-Inflammatory Effects of Oryza Sativa (Rice) Bran Extract on Lipopolysaccharide-Induced Inflammation in RAW 264.7 Macrophages. Journal of Medicinal Food, 21(10), 1040-1048.

- Kim, S. H., et al. (2016). Skin Brightening Effects of Oryza Sativa (Rice) Bran Extract on UVB-induced Skin Pigmentation in Guinea Pigs. Journal of Cosmetic Dermatology, 15(4), 454-460.

1. Definition Bletilla Striata Root Extract:

Bletilla Striata Root Extract is a natural ingredient derived from the Bletilla striata plant, also known as the Chinese ground orchid. It is commonly used in skincare products for its hydrating, soothing, and anti-inflammatory properties.

2. Use:

Bletilla Striata Root Extract is used in cosmetics for its ability to improve skin hydration, reduce redness and irritation, and promote overall skin health. It is often found in moisturizers, serums, and masks designed to calm and nourish the skin.

3. Usage Bletilla Striata Root Extract:

When using products containing Bletilla Striata Root Extract, it is important to patch test first to ensure compatibility with your skin. Start by applying a small amount of the product to a small area of skin and wait 24 hours to check for any adverse reactions. If no irritation occurs, you can proceed to use the product as directed. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Kim, J. H., Kim, S. W., Kim, H. J., & Jeon, S. (2018). The anti-inflammatory effects of Bletilla striata on phthalic anhydride-induced atopic dermatitis in vivo and in vitro. Journal of Ethnopharmacology, 226, 25-32.

- Wang, L., Zhao, X., & Wei, J. (2018). The anti-inflammatory and antioxidant effects of Bletilla striata on COPD rats. Biomedicine & Pharmacotherapy, 98, 745-751.

- Zhao, X., Wang, L., & Wei, J. (2017). Protective effects of Bletilla striata polysaccharide on lipopolysaccharide-induced acute lung injury by activating the Nrf2 pathway and inhibiting the NLRP3 pathway. International Journal of Biological Macromolecules, 105, 1049-1055.