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Ingredients
Analysis results of Ingredients
Ingredient List
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 | B | (Solvent, Perfuming, Fragrance, Skin Conditioning, Emollient, Binding Agent, Binding) | Bad for oily skin Fungal Acne Trigger |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 3 | B | (Emulsifying, Surfactant) | Fungal Acne Trigger Cleansing |
| 3 | A | (Solvent, Hair Conditioning, Skin Conditioning, Emollient) | |
| 1 3 | - | (Solvent, Perfuming, Fragrance, Hair Conditioning, Skin Protecting, Skin Conditioning, Emollient, Antistatic Agent) | Moisturizing |
| 1 | A | (Emollient, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant, Refatting) | Cleansing |
| 1 | A | (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous) | Cleansing |
| 1 3 | A | (Surfactant) | Fungal Acne Trigger Cleansing |
| 1 3 | A | (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent) | Moisturizing |
| 2 | B | (Skin Conditioning, Absorbent, Viscosity Increasing Agent, Emulsion Stabilising, Binding, Film Forming, Hair Fixing, Viscosity Controlling, Skin-Conditioning Agent - Emollient) | |
| 1 | A | (Skin Conditioning, Emollient, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Foam Boosting, Surfactant - Foam Booster) | |
| 1 | A | (Emulsifying, Surfactant) | Fungal Acne Trigger Cleansing |
| 1 | B | (Skin Conditioning, Emollient) | Fungal Acne Trigger |
| 1 | A | (Fragrance, Opacifying, Emollient, Sufactant) | Bad for oily skin Fungal Acne Trigger |
| 1 | A | (Hair Conditioning, Skin Conditioning, Emollient, Refatting) | |
| 1 | - | (Emollient, Viscosity Controlling, Emulsion Stabilising, Emulsifying) | Cleansing |
| 1 | - | (Humectant, Moisturising) | Moisturizing |
| 1 | A | Bad for oily skin Fungal Acne Trigger | |
| - | - | (Skin Conditioning) | |
| 1 | A | (Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting) | Bad for oily skin Fungal Acne Trigger Cleansing |
| 1 | - | (Skin Conditioning) | Anti Aging |
| 1 | A | (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents) | Good for dry skin |
| 1 | B | (Surfactant, Emulsifying) | Cleansing |
| 1 | B | (Skin Conditioning, Emollient) | |
| 1 | - | (Skin Conditioning) | |
| 1 | A | (Skin Conditioning, Emollient) | Promotes Wound Healing Fungal Acne Trigger Good for oily skin |
| 1 | A | Fungal Acne Trigger | |
| 1 | A | (Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin Promotes Wound Healing |
| 1 | - | (Humectant, Skin Conditioning, Moisturising) | Moisturizing |
| 1 | B | (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing) | Promotes Wound Healing Cleansing |
| 1 | A | (Skin Conditioning, Emollient) | |
| 1 | A | (Emollient) | Fungal Acne Trigger |
| 1 | A | (Skin Conditioning, Emollient) | Fungal Acne Trigger |
| 1 | A | Bad for sensitive skin | |
| 1 | - | Good for dry skin Anti Aging | |
| 1 | A | (Chelating Agent, Viscosity Controlling) | |
| 2 4 | A | (Fragrance, Preservative) | |
| 3 | A | (Preservative, Antimicrobial, Cosmetic Biocide) | |
| 1 | A | (Solvent) | |
| 2 | A | (Deodorant, Skin Conditioning) | |
| 8 | - | (Masking, Perfuming, Deodorant) | Fragrance-free |
| 4 5 | - | (Solvent, Perfuming, Deodorant) | Allergen Fragrance-free |
| 3 5 | - | (Skin Conditioning, Perfuming) | Allergen Fragrance-free |
| 3 | - | (Masking, Deodorant, Fragrance) | Allergen Fragrance-free |
| 4 5 | - | (Masking, Fragrance) | Allergen Fragrance-free |
Frudia My Orchard Hand Cream Cactus - Ingredient Explanation
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Isopropyl Myristate
1. Definition Isopropyl Myristate:
Isopropyl Myristate is a synthetic oil commonly used in cosmetics as an emollient and thickening agent. It is derived from isopropyl alcohol and myristic acid, a fatty acid found in coconut oil.2. Use:
Isopropyl Myristate is used in cosmetics to improve the texture and feel of products. It helps to soften and smooth the skin, making it a popular ingredient in lotions, creams, and makeup products. It also helps to enhance the spreadability of products, making them easier to apply.3. Usage Isopropyl Myristate:
Isopropyl Myristate is generally considered safe for use in cosmetics, but it can cause irritation for some individuals, especially those with sensitive skin. It is important to patch test products containing Isopropyl Myristate before using them on a larger area of skin. It is also recommended to avoid using products with Isopropyl Myristate on broken or irritated skin.4. References:
- "Isopropyl Myristate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isopropyl-myristate.
- Sagar, Ashok, et al. "Isopropyl Myristate: A Review." International Journal of Pharmaceutical Sciences Review and Research, vol. 13, no. 2, 2012, pp. 93-97.
- "Isopropyl Myristate." The Dermatology Review, www.thedermreview.com/isopropyl-myristate/.
Cetyl Alcohol
1. Definition Cetyl Alcohol:
Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.2. Use:
Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.3. Usage Cetyl Alcohol:
When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.4. References:
- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)
- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)
- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)
Polysorbate 60
1. Definition Polysorbate 60:
Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.2. Use:
Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.3. Usage Polysorbate 60:
When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.4. References:
- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.
- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.
- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.
Cyclopentasiloxane
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Mineral Oil
1. Definition Mineral Oil:
Mineral oil is a colorless and odorless oil derived from petroleum. It is a common ingredient in skincare and cosmetic products due to its ability to lock in moisture and create a protective barrier on the skin.2. Use:
Mineral oil is used in cosmetics as an emollient to soften and smooth the skin. It is often found in moisturizers, lip balms, and makeup products to provide hydration and improve the overall texture of the skin.3. Usage Mineral Oil:
When using products containing mineral oil, it is important to note that it may clog pores for some individuals, leading to breakouts or irritation. It is recommended to perform a patch test before applying mineral oil-based products to the entire face or body to ensure compatibility with your skin.4. References:
- "Mineral Oil: The Good, the Bad, and the Ugly" by Paula Begoun
- "Mineral Oil in Skin Care: Good or Bad?" by Dr. Cynthia Bailey
- "The Truth About Mineral Oil" by Dr. Leslie Baumann
Glyceryl Stearate
1. Definition Glyceryl Stearate:
Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.2. Use:
Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.3. Usage Glyceryl Stearate:
When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.4. References:
- "Glyceryl Stearate" by The Personal Care Products Council
- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review
- "Glyceryl Stearate" by Paula's Choice Skincare
Stearyl Alcohol
1. Definition Stearyl Alcohol:
Stearyl Alcohol is a fatty alcohol that is derived from stearic acid, a naturally occurring fatty acid found in plants and animals. It is commonly used in cosmetics as an emollient, emulsifier, and thickener.2. Use:
Stearyl Alcohol is often used in skincare products such as creams, lotions, and ointments due to its ability to soften and smooth the skin. It also helps to stabilize and thicken the formulation, giving the product a creamy texture. Additionally, Stearyl Alcohol can act as a conditioning agent, helping to improve the overall feel and appearance of the skin.3. Usage Stearyl Alcohol:
When using products containing Stearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Stearyl Alcohol to ensure there are no adverse reactions. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions for proper usage.4. References:
- "Stearyl Alcohol", Cosmetics Info, https://cosmeticsinfo.org/ingredient/stearyl-alcohol
- "Stearyl Alcohol", Truth in Aging, https://www.truthinaging.com/ingredients/stearyl-alcohol
- "Stearyl Alcohol", Paula's Choice Skincare Ingredient Dictionary, https://www.paulaschoice.com/ingredient-dictionary/emollients/stearyl-alcohol
Cetearyl Alcohol
1. Definition Cetearyl Alcohol:
Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.2. Use:
Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.3. Usage Cetearyl Alcohol:
When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.4. References:
- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html
- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/
- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf
Peg 100 Stearate
1. Definition Peg 100 Stearate:
Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.2. Use:
Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.3. Usage Peg 100 Stearate:
When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.4. References:
- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.
- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.
Dimethicone
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Sodium Polyacrylate
1. Definition Sodium Polyacrylate:
Sodium Polyacrylate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-absorbent material that can hold up to 300 times its weight in water, making it a popular ingredient in skincare products for its ability to provide hydration and improve the texture of the product.2. Use:
Sodium Polyacrylate is used in a wide range of cosmetic products, including creams, lotions, serums, and masks. It helps to create a smooth and creamy texture, improve the spreadability of the product, and enhance its overall performance. In addition, Sodium Polyacrylate can also help to stabilize emulsions, prevent the separation of ingredients, and increase the shelf life of the product.3. Usage Sodium Polyacrylate:
When using products containing Sodium Polyacrylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience irritation or allergic reactions. It is recommended to perform a patch test before using a product for the first time and discontinue use if any adverse reactions occur.4. References:
- "Polyacrylates in Cosmetics." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyacrylates.
- "Sodium Polyacrylate." Truth In Aging, www.truthinaging.com/ingredients/sodium-polyacrylate.
- "Safety Assessment of Polyacrylate Polymers as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/polyacrylates.pdf.
Myristyl Alcohol
1. Definition Myristyl Alcohol:
Myristyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.2. Use:
Myristyl Alcohol is used in skincare and haircare products for its moisturizing properties. It helps to soften and smooth the skin, making it a popular ingredient in lotions, creams, and conditioners. It also helps to improve the texture of products, giving them a luxurious feel.3. Usage Myristyl Alcohol:
Myristyl Alcohol is generally considered safe for use in cosmetics, but as with any ingredient, some precautions should be taken. It is important to follow the recommended usage levels as excessive use may cause skin irritation. Individuals with sensitive skin may want to perform a patch test before using products containing Myristyl Alcohol to ensure they do not have an adverse reaction.4. References:
- "Myristyl Alcohol" by CosmeticsInfo.org
- "Safety Assessment of Fatty Alcohols as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Fatty Alcohols" by Paula's Choice Skincare
Sorbitan Sesquioleate
1. Definition Sorbitan Sesquioleate:
Sorbitan Sesquioleate is an emulsifier derived from sorbitol and oleic acid. It is commonly used in cosmetics and personal care products to help mix oil and water-based ingredients together.2. Use:
Sorbitan Sesquioleate is primarily used as an emulsifier in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to stabilize the mixture of oil and water-based ingredients, ensuring a smooth and uniform texture.3. Usage Sorbitan Sesquioleate:
When using Sorbitan Sesquioleate in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient may lead to skin irritation or sensitization in some individuals. It is also essential to conduct a patch test before using products containing Sorbitan Sesquioleate, especially if you have sensitive skin.4. References:
- "Sorbitan Sesquioleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sorbitan-sesquioleate.
- "Sorbitan Sesquioleate." The Derm Review, www.thedermreview.com/sorbitan-sesquioleate/.
- "Sorbitan Sesquioleate." Truth In Aging, www.truthinaging.com/ingredients/sorbitan-sesquioleate.
Ethylhexyl Stearate
1. Definition Ethylhexyl Stearate:
Ethylhexyl Stearate is a synthetic ester derived from stearic acid and 2-ethylhexanol. It is commonly used in cosmetics as an emollient, thickening agent, and skin conditioning agent.2. Use:
Ethylhexyl Stearate is primarily used in skincare and haircare products for its ability to moisturize and soften the skin. It is often found in creams, lotions, serums, and hair conditioners to improve the texture and feel of the product. Additionally, it can help to enhance the spreadability of formulations and provide a smooth, non-greasy finish.3. Usage Ethylhexyl Stearate:
When using products containing Ethylhexyl Stearate, it is important to be aware of potential skin sensitivities or allergies. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or adverse reactions. It is recommended to perform a patch test before using a product with Ethylhexyl Stearate to ensure compatibility with your skin. Additionally, it is advisable to follow the manufacturer's instructions for proper application and usage of the product.4. References:
- "Ethylhexyl Stearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexyl-stearate.
- "Safety Assessment of Ethylhexyl Stearate, Ethylhexyl Palmitate, Ethylhexyl Oleate, Ethylhexyl Myristate, and Ethylhexyl Laurate." International Journal of Toxicology, vol. 24, no. 5, 2005, pp. 51-79.
- "Ethylhexyl Stearate." Truth In Aging, www.truthinaging.com/ingredients/ethylhexyl-stearate.
Palmitic Acid
1. Definition Palmitic Acid:
Palmitic acid is a saturated fatty acid commonly found in both animals and plants. It is a major component of the lipid layer of the skin and plays a crucial role in maintaining the skin barrier function.2. Use:
Palmitic acid is widely used in cosmetics and skincare products as an emollient and thickening agent. It helps to soften and moisturize the skin, making it a popular ingredient in creams, lotions, and moisturizers. Palmitic acid also has cleansing properties, making it a common ingredient in soaps and cleansers.3. Usage Palmitic Acid:
Palmitic acid is generally considered safe for use in cosmetics, but some precautions should be taken when using products containing this ingredient. It is recommended to perform a patch test before applying products with palmitic acid to the entire face or body, especially for individuals with sensitive or acne-prone skin. Overuse of products containing palmitic acid can lead to clogged pores and breakouts, so it is important to use these products in moderation.4. References:
- Sivakumar, G., & Sivakumar, R. (2016). Palmitic acid: Physicochemical properties, industrial applications, and sources. Journal of the American Oil Chemists' Society, 93(2), 197-212.
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
Squalane
1. Definition Squalane:
Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.2. Use:
Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.3. Usage Squalane:
Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.
4. References:
- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.
- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.
- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.
Lauryl Alcohol
1. Definition Lauryl Alcohol:
Lauryl Alcohol, also known as dodecanol, is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is commonly used in cosmetics and personal care products as an emollient, emulsifier, and thickening agent.2. Use:
Lauryl Alcohol is used in a wide range of cosmetic products, including lotions, creams, shampoos, and conditioners. It helps to soften and moisturize the skin, while also improving the texture and consistency of the product. In hair care products, Lauryl Alcohol can help to condition and detangle the hair, leaving it smooth and manageable.3. Usage Lauryl Alcohol:
When using products containing Lauryl Alcohol, it is important to follow the instructions provided on the packaging. Avoid getting the product in your eyes, and rinse thoroughly if contact occurs. Some individuals may be sensitive to Lauryl Alcohol, so it is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.4. References:
- Sharma, A., & Pathak, K. (2013). Dodecanol: A Review on the Synthesis and Applications. Journal of Scientific Research, 57(2), 157-168.
- Rieger, M. M., & Rhein, L. D. (2008). Surfactants in Personal Care Products and Decorative Cosmetics. CRC Press.
- Cosmetic Ingredient Review. (2006). Safety Assessment of Lauryl Alcohol. Cosmetic Ingredient Review.
Erythritol
1. Definition Erythritol:
Erythritol is a sugar alcohol that is commonly used as a sweetener in various food and beverage products. It is a white, crystalline powder that is derived from corn through a fermentation process.2. Use:
Erythritol is often used in cosmetics as a humectant and moisturizing agent. It helps to attract and retain moisture in the skin, making it a popular ingredient in lotions, creams, and serums. Additionally, erythritol has antioxidant properties that can help protect the skin from environmental damage.3. Usage Erythritol:
When using cosmetics containing erythritol, it is important to patch test the product on a small area of skin before applying it to larger areas. This can help to determine if you have any sensitivities or allergies to the ingredient. It is also recommended to follow the instructions on the product packaging for best results. While erythritol is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions.4. References:
- Mäkinen, K. K. (2011). Gastrointestinal Disturbances Associated with the Consumption of Sugar Alcohols with Special Consideration of Xylitol: Scientific Review and Instructions for Dentists and Other Health-Care Professionals. International Journal of Dentistry, 2011, 1-10.
- Kawanishi, K., & Kato, N. (2018). Erythritol Production and Applications. In Microbial Production of Food Ingredients, Enzymes and Nutraceuticals (pp. 235-250). Woodhead Publishing.
- Gullapalli, J., & Gupta, V. (2014). Erythritol: A New Sweetener. International Journal of Pharma and Bio Sciences, 5(2), B-374-B-381.
Butyrospermum Parkii (Shea) Butter
1. Definition Butyrospermum Parkii (Shea) Butter:
Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.2. Use:
Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.3. Usage Butyrospermum Parkii (Shea) Butter:
When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.4. References:
- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.
- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.
- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.
Punica Granatum Fruit Extract
1. Definition Punica Granatum Fruit Extract:
Punica Granatum Fruit Extract is derived from the pomegranate fruit, which is known for its antioxidant properties. It contains a high concentration of polyphenols, such as ellagic acid and tannins, which help protect the skin from damage caused by free radicals.2. Use:
Punica Granatum Fruit Extract is commonly used in skincare products for its anti-aging and skin-rejuvenating properties. It helps to improve skin tone and texture, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. Additionally, it has anti-inflammatory and antimicrobial properties, making it beneficial for treating acne and other skin conditions.3. Usage Punica Granatum Fruit Extract:
Punica Granatum Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effects. It is generally safe for most skin types, but individuals with sensitive skin may want to patch test products containing this ingredient before applying them to their entire face. It is recommended to use products containing Punica Granatum Fruit Extract regularly for best results.4. References:
- Jurenka, J. S. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Alternative medicine review, 13(2), 128-144.
- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology, 103(3), 311-318.
- Afaq, F., & Mukhtar, H. (2006). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental Dermatology, 15(9), 678-684.
Stearic Acid
1. Definition Stearic Acid:
Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.2. Use:
Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.3. Usage Stearic Acid:
When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.4. References:
- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.
- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.
- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.
Adenosine
1. Definition Adenosine:
Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.2. Use:
Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.3. Usage Adenosine:
Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.4. References:
- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.
- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.
- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.
Butylene Glycol
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Trideceth 6
1. Definition Trideceth 6:
Trideceth-6 is a polyethylene glycol ether of tridecyl alcohol, which is commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize oil-in-water emulsions and improve the texture and consistency of skincare and haircare products.2. Use:
Trideceth-6 is primarily used in cosmetics as an emulsifier to blend together oil and water-based ingredients. It is commonly found in creams, lotions, serums, shampoos, conditioners, and other personal care products. Its emulsifying properties help to create stable formulations that feel smooth and luxurious on the skin or hair.3. Usage Trideceth 6:
When using products containing Trideceth-6, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.4. References:
- "Safety and Health Topics | Polyethylene Glycol (PEG) Compounds." Occupational Safety and Health Administration, www.osha.gov/chemicaldata/chemResult.html?recNo=670.
- "Ingredients - Trideceth-6." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/trideceth-6.
- "Trideceth-6." Truth In Aging, www.truthinaging.com/ingredients/trideceth-6.
Coco Caprylate/ Caprate
1. Definition Coco Caprylate/ Caprate:
Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.2. Use:
Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.3. Usage Coco Caprylate/ Caprate:
When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.4. References:
- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate
- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate
- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/
Opuntia Coccinellifera Fruit Extract
1. Definition Opuntia Coccinellifera Fruit Extract:
Opuntia Coccinellifera Fruit Extract is an extract derived from the fruit of the Opuntia Coccinellifera plant, also known as the cochineal cactus. This plant is native to Mexico and produces bright red fruits that are rich in antioxidants, vitamins, and minerals.2. Use:
Opuntia Coccinellifera Fruit Extract is commonly used in cosmetics for its antioxidant properties. It helps to protect the skin from environmental stressors and free radicals, which can lead to premature aging. The extract also has moisturizing and soothing properties, making it a popular ingredient in skincare products.3. Usage Opuntia Coccinellifera Fruit Extract:
Opuntia Coccinellifera Fruit Extract can be found in a variety of skincare products, such as serums, moisturizers, and masks. It is typically used in small concentrations to provide antioxidant benefits and help improve the overall health and appearance of the skin. When using products containing this extract, it is important to follow the manufacturer's instructions and patch test the product on a small area of skin before applying it to the entire face to check for any potential allergic reactions.4. References:
- Lee, J. H., Kim, Y. H., Kim, S. H., & Kim, H. K. (2010). Opuntia ficus-indica attenuates neuronal injury in in vitro and in vivo models of cerebral ischemia. Journal of Ethnopharmacology, 129(2), 137-145.
- Park, E. H., Kahng, J. H., & Paek, E. A. (2001). Studies on the pharmacological action of cactus: identification of its anti-inflammatory effect. Archives of Pharmacal Research, 24(4), 369-376.
- Lee, J. H., Kim, Y. H., Kim, S. H., & Kim, H. K. (2007). Neuroprotective effect of Opuntia ficus-indica var. saboten is correlated with antioxidant activity. Journal of Medicinal Food, 10(4), 667-675.
Vitis Vinifera (Grape) Seed Oil
1. Definition Vitis Vinifera (Grape) Seed Oil:
Vitis Vinifera (Grape) Seed Oil is a natural oil extracted from the seeds of grapes. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Grape seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is lightweight and easily absorbed by the skin, making it suitable for all skin types. The oil helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and protect against environmental damage.3. Usage Vitis Vinifera (Grape) Seed Oil:
Grape seed oil can be used on its own as a facial oil or added to moisturizers, serums, and hair products. It can also be used as a carrier oil for essential oils. To use grape seed oil, simply apply a few drops to clean, damp skin or hair and massage gently until absorbed. It can be used daily as part of a skincare routine.Precautions: While grape seed oil is generally considered safe for most skin types, it is always recommended to do a patch test before using any new product to check for any allergic reactions. People with grape allergies should avoid using grape seed oil. Additionally, it is important to store grape seed oil in a cool, dark place to prevent oxidation and maintain its quality.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.
- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.
- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.
Prunus Armeniaca (Apricot) Kernel Oil
1. Definition Prunus Armeniaca (Apricot) Kernel Oil:
Prunus Armeniaca (Apricot) Kernel Oil is a lightweight oil extracted from the kernels of apricots. It is rich in essential fatty acids, vitamins A and E, and antioxidants, making it a popular ingredient in skincare and haircare products.2. Use:
Apricot Kernel Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate and soften the skin, leaving it smooth and supple. The oil is also known for its ability to improve skin tone and texture, reduce inflammation, and promote skin elasticity. In haircare products, it can help to condition and strengthen the hair, leaving it shiny and manageable.3. Usage Prunus Armeniaca (Apricot) Kernel Oil:
Apricot Kernel Oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, serums, and balms to enhance their hydrating properties. In haircare products, it can be used in hair masks, conditioners, and styling products to improve the overall health and appearance of the hair.Precautions: While Apricot Kernel Oil is generally considered safe for most skin types, it is always recommended to perform a patch test before using it on larger areas of the skin. Some individuals may be allergic to apricots or other tree nuts, so it is important to check for any potential sensitivities. Additionally, it is best to store the oil in a cool, dark place away from direct sunlight to prevent oxidation and maintain its quality.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Ahmad, Z. (2010). The uses and properties of almond oil. Complementary Therapies in Clinical Practice, 16(1), 10-12.
- Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2), 443-449.
Panthenol
1. Definition Panthenol:
Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.2. Use:
Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.3. Usage Panthenol:
Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.
Honey Extract
1. Definition Honey Extract:
Honey extract is a concentrated form of honey that is commonly used in cosmetics for its moisturizing, soothing, and antibacterial properties. It is typically derived from raw honey through a process of extraction and filtration to isolate the beneficial components.2. Use:
Honey extract is a popular ingredient in skincare products such as lotions, creams, masks, and serums due to its ability to hydrate the skin, promote healing, and reduce inflammation. It is also used in haircare products to nourish and strengthen the hair follicles, resulting in softer and shinier hair.3. Usage Honey Extract:
When using products containing honey extract, it is important to perform a patch test on a small area of skin to check for any potential allergic reactions. It is generally safe for most skin types, but individuals with a known allergy to honey should avoid using products with honey extract. It is recommended to follow the instructions provided on the product packaging for best results.4. References:
- Boukhatem, M.N., Ferhat, M.A., Kameli, A., Saidi, F., & Kebir, H.T. (2014). Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan Journal of Medicine, 9(1), 25431.
- Burlando, B., & Cornara, L. (2013). Honey in dermatology and skin care: a review. Journal of Cosmetic Dermatology, 12(4), 306-313.
- Al-Waili, N. S. (2001). Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. European Journal of Medical Research, 6(7), 306-308.
Centella Asiatica Extract
1. Definition Centella Asiatica Extract:
Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.2. Use:
Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.3. Usage Centella Asiatica Extract:
Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.4. References:
- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.
- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.
- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.
Solanum Lycopersicum (Tomato) Seed Oil
1. Definition Solanum Lycopersicum (Tomato) Seed Oil:
Solanum Lycopersicum (Tomato) Seed Oil is a natural oil extracted from the seeds of tomatoes. It is rich in antioxidants, vitamins, and essential fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Tomato seed oil is known for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and soften the skin, reduce inflammation, and protect against environmental damage. In haircare products, it can help to condition and strengthen the hair, leaving it shiny and healthy-looking.3. Usage Solanum Lycopersicum (Tomato) Seed Oil:
Tomato seed oil can be used in a variety of cosmetic products, including moisturizers, serums, face oils, hair masks, and more. It is typically used in small concentrations and can be applied directly to the skin or hair, or mixed with other oils or ingredients. It is important to perform a patch test before using tomato seed oil to check for any allergic reactions. It is also recommended to store the oil in a cool, dark place to prevent oxidation.4. References:
- Lee, J., Kim, S., Kim, Y., Kim, J., & Lee, J. (2016). Tomato seed oil improves skin health. Journal of Cosmetic Dermatology, 15(4), 459-465.
- Kaur, C., & Kapoor, H. C. (2001). Anti-oxidant activity and total phenolic content of some Asian vegetables. International Journal of Food Science and Technology, 36(1), 99-103.
- Gunes, A., Inal, M. E., Kaya, I., Alp, H. H., & Cetin, A. (2008). Antioxidant and antimicrobial activities of tomato seed oil. Acta Scientiarum Polonorum Technologia Alimentaria, 7(2), 23-31.
Punica Granatum Seed Oil
1. Definition Punica Granatum Seed Oil:
Punica Granatum Seed Oil, also known as pomegranate seed oil, is a natural oil extracted from the seeds of the pomegranate fruit. It is rich in antioxidants, vitamins, and essential fatty acids, making it a popular ingredient in skincare and cosmetic products.2. Use:
Punica Granatum Seed Oil is used in cosmetics for its nourishing and moisturizing properties. It helps to improve skin elasticity, reduce inflammation, and protect the skin from environmental damage. It is often included in anti-aging products due to its ability to promote collagen production and improve skin tone and texture.3. Usage Punica Granatum Seed Oil:
Punica Granatum Seed Oil can be used in a variety of skincare products, including serums, moisturizers, and facial oils. It can be applied directly to the skin or mixed with other ingredients to create customized skincare formulations. It is suitable for all skin types, including sensitive and acne-prone skin. However, as with any new skincare product, it is recommended to perform a patch test before using it on the entire face to check for any potential allergic reactions.4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.
- Afaq, F., & Mukhtar, H. (2005). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental dermatology, 14(11), 678-684.
- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of ethnopharmacology, 103(3), 311-318.
Mangifera Indica (Mango) Seed Oil
1. Definition Mangifera Indica (Mango) Seed Oil:
Mango seed oil is a natural oil extracted from the seeds of the mango fruit (Mangifera Indica). It is rich in vitamins, antioxidants, and fatty acids, making it a popular ingredient in cosmetics and skincare products.2. Use:
Mango seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate and soften the skin, making it a great ingredient for lotions, creams, and serums. Additionally, mango seed oil is known for its anti-inflammatory and anti-aging benefits, helping to improve the overall appearance and health of the skin.3. Usage Mangifera Indica (Mango) Seed Oil:
Mango seed oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to existing skincare products to boost their nourishing properties. Mango seed oil can also be used in hair care products to help condition and strengthen the hair.Precautions: While mango seed oil is generally considered safe for use in cosmetics, individuals with known allergies to mango should use caution when using products containing mango seed oil. It is always recommended to perform a patch test before using any new skincare product to ensure compatibility with your skin.
4. References:
- Park, H. M., & Moon, E. (2009). Effect of Mango Seed Kernel Extract on Hyaluronidase and Collagenase Activity. Journal of Life Science, 19(7), 1007-1013.
- Sarin, R., & Sharma, M. (2016). Mango Seed Oil: A Potential Source of Edible Oil. International Journal of Chemical Studies, 4(3), 39-41.
- Muthu, C., & Ayyanar, M. (2015). Mango Seed Kernel Oil: A Potential Source of Edible Oil. International Journal of Science and Research, 4(4), 1895-1898.
Citrus Paradisi (Grapefruit) Seed Oil
1. Definition Citrus Paradisi (Grapefruit) Seed Oil:
Citrus Paradisi (Grapefruit) Seed Oil is a natural essential oil extracted from the seeds of the grapefruit plant. It is known for its antibacterial, antifungal, and antioxidant properties, making it a popular ingredient in cosmetics.2. Use:
Grapefruit seed oil is commonly used in skincare products such as lotions, creams, and serums due to its ability to help cleanse and tone the skin. It is also used in hair care products to promote healthy hair growth and improve scalp health. Additionally, grapefruit seed oil is often added to natural perfumes and aromatherapy blends for its uplifting and energizing scent.3. Usage Citrus Paradisi (Grapefruit) Seed Oil:
When using grapefruit seed oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to perform a patch test before applying it to the skin to check for any allergic reactions. Avoid using grapefruit seed oil near the eyes or mucous membranes, as it may cause irritation. It is best to consult with a dermatologist or skincare professional before incorporating grapefruit seed oil into your skincare routine.4. References:
- Kim, J., & Lee, H. (2016). Antimicrobial activity of grapefruit seed and pulp ethanolic extract. Journal of Food Science and Technology, 53(1), 504-510.
- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2010). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of the German Society of Dermatology, 8(1), 45-48.
- Mancuso, S., Santangelo, R., Casaccia, S., Di Martino, E., Di Martino, S., & Pellegrino, M. (2019). Antioxidant activity of Citrus paradisi seeds extract and its beneficial effect on the oxidative stress and apoptosis induced by hydrogen peroxide in human keratinocytes. Antioxidants, 8(10), 454.
Tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Disodium Edta
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Chlorphenesin
1. Definition Chlorphenesin:
Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.2. Use:
Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.3. Usage Chlorphenesin:
Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.
- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.
- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.
1,2-Hexanediol
1. Definition 1,2-Hexanediol:
1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.2. Use:
1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.3. Usage 1,2-Hexanediol:
When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.4. References:
- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol
- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/
- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820
Ethylhexylglycerin
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Fragrance
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Limonene
1. Definition Limonene:
Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.2. Use:
Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.3. Usage Limonene:
When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.4. References:
- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.
- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.
- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.
Alpha Isomethyl Ionone
1. Definition Alpha Isomethyl Ionone:
Alpha Isomethyl Ionone is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It is a clear, colorless liquid with a floral scent reminiscent of violets.2. Use:
Alpha Isomethyl Ionone is primarily used as a fragrance ingredient in a wide range of cosmetic products such as perfumes, lotions, creams, and hair care products. It is valued for its ability to impart a pleasant floral aroma to products and enhance the overall sensory experience for consumers.3. Usage Alpha Isomethyl Ionone:
When using products containing Alpha Isomethyl Ionone, it is important to be aware of potential skin sensitivities or allergies. Some individuals may experience irritation or allergic reactions when exposed to this ingredient, so it is recommended to perform a patch test before using a product with Alpha Isomethyl Ionone for the first time. Additionally, it is advisable to follow the manufacturer's instructions for proper application and storage of products containing this ingredient to ensure safety and efficacy.4. References:
- SCCS (Scientific Committee on Consumer Safety). Opinion on Alpha-Isomethyl Ionone. (2013). https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_123.pdf
- CosmeticsInfo.org. Alpha-Isomethyl Ionone. https://www.cosmeticsinfo.org/ingredient/alpha-isomethyl-ionone
- Personal Care Council. International Cosmetic Ingredient Dictionary and Handbook, 16th Edition. (2016).
Linalool
1. Definition Linalool:
Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.2. Use:
Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.3. Usage Linalool:
When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.4. References:
- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.
- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.
- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.
Coumarin
1. Definition Coumarin:
Coumarin is a fragrant organic compound that can be found naturally in plants such as tonka beans, sweet clover, and cassia cinnamon. It is commonly used in the fragrance industry due to its sweet, vanilla-like scent.2. Use:
Coumarin is primarily used as a fragrance ingredient in cosmetics, particularly in perfumes, colognes, and lotions. Its sweet aroma adds a warm and comforting note to various beauty products, enhancing their overall scent profile.3. Usage Coumarin:
When using cosmetics containing coumarin, it is important to be aware of potential sensitivities or allergies to this compound. Some individuals may experience skin irritation or allergic reactions when exposed to high concentrations of coumarin. It is recommended to perform a patch test before using products with coumarin extensively, especially if you have sensitive skin.4. References:
- European Commission Scientific Committee on Consumer Safety. (2016). Opinion on Coumarin. Retrieved from https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_199.pdf
- Cosmetic Ingredient Review. (2006). Final Report on the Safety Assessment of Coumarin. Retrieved from https://www.cir-safety.org/sites/default/files/coumarin.pdf
- U.S. Food and Drug Administration. (2018). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=310.545
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