G.M. Collin Daily Ceramide Comfort

1. Definition Glycine Soja (Soybean) Oil Unsaponifiables:

2. Use:

3. Usage Glycine Soja (Soybean) Oil Unsaponifiables:

4. References:

- De Spirt S, Stahl W, Tronnier H, Sies H, Bejot M, Maurette JM, Heinrich U. Intervention with flaxseed and borage oil supplements modulates skin condition in women. Br J Nutr. 2009;101(3):440-5. doi: 10.1017/S0007114508011473.

- Gopaul R, Knaggs HE, Lephart JF, Holley KC, Gibson EM. The influence of botanical extracts, soy protein, and soybean isoflavones on the growth of Staphylococcus epidermidis. Int J Cosmet Sci. 2008;30(1):41-7. doi: 10.1111/j.1467-2494.2007.00401.x.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi: 10.3390/ijms19010070.

1. Definition Olea Europaea (Olive) Oil Unsaponifiables:

2. Use:

3. Usage Olea Europaea (Olive) Oil Unsaponifiables:

4. References:

- Montenegro L, Pasquinucci L. Olive Oil Unsaponifiables in Skincare and Skin Disease. Cosmetics. 2020;7(1):6. doi:10.3390/cosmetics7010006

- Gómez-Rico A, Salvador MD, La Greca M, Fregapane G. Phenolic and volatile compounds of extra virgin olive oil (Olea europaea L. Cv. Cornicabra) with regard to fruit ripening and irrigation management. J Agric Food Chem. 2006;54(8):3121-3130. doi:10.1021/jf053111p

- Sánchez de Medina V, Prieto I, Galvez J, et al. Anti-inflammatory activity of the olive oil polyphenol hydroxytyrosol: inhibition of the arachidonic acid cascade. Clin Nutr. 2009;28(4):350-355. doi:10.1016/j.clnu.2009.03.011

1. Definition Triticum Vulgare (Wheat) Germ Oil Unsaponifiables:

2. Use:

3. Usage Triticum Vulgare (Wheat) Germ Oil Unsaponifiables:

4. References:

- Choe E, Min DB. Mechanisms of antioxidants in the oxidation of foods. Compr Rev Food Sci Food Saf. 2009;8(4):345-358.

- Gharby S, Harhar H, Guillaume D, et al. Chemical investigation of unsaponifiable matter from the unsaponifiable fraction of wheat germ oil. Chem Cent J. 2017;11:20.

- Katsarou A, Gioxari A, Giokas G, et al. Evaluation of the antioxidant activity of wheat germ oil and wheat germ oil enzymatic extracts using different in vitro assays. J Food Qual. 2018;2018:1-10.

1. Definition Lupinus Albus Seed Oil:

2. Use:

3. Usage Lupinus Albus Seed Oil:

4. References:

- Puglia C, et al. (2015). Chemical composition and antioxidant properties of seed oil from Lupinus albus L. https://pubmed.ncbi.nlm.nih.gov/25900791/

- Lopes G, et al. (2017). White Lupin (Lupinus albus L.) Seed Oil: A Rich Source of Alpha-Linolenic Acid with Antioxidant and Anti-Inflammatory Properties. https://pubmed.ncbi.nlm.nih.gov/28587226/

- Gómez-Caravaca AM, et al. (2019). Lupinus albus Seed Oil: A Potential New Source of Health-Beneficial Omega-3 Fatty Acids. https://pubmed.ncbi.nlm.nih.gov/31561475/

1. Definition Ceramide 3:

2. Use:

3. Usage Ceramide 3:

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Isodecyl Salicylate:

2. Use:

3. Usage Isodecyl Salicylate:

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final report on the safety assessment of salicylic acid, butyloctyl salicylate, calcium salicylate, C12-15 alkyl salicylate, C12-15 alkyl lactate, C12-15 alkyl citrate, C12-15 alkyl malate, decyl salicylate, Dodecyl salicylate, dodecyl salicylate, isodecyl salicylate, isocetyl salicylate, octyl salicylate, and triisocetyl salicylate. International journal of toxicology, 31(5_suppl), 1-77.

- Isodecyl Salicylate. (n.d.). Retrieved from https://cosmeticsinfo.org/ingredient/isodecyl-salicylate

- Isodecyl Salicylate. (n.d.). Retrieved from https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/isodecyl-salicylate

1. Definition Isopropylbenzyl Salicylate:

2. Use:

3. Usage Isopropylbenzyl Salicylate:

4. References:

- Cosmetic Ingredient Review Expert Panel. (2007). Final report on the safety assessment of benzyl salicylate, octyldodecyl benzoate, octyldodecyl stearoyl stearate, and the various acetyl triethyl citrate. International Journal of Toxicology, 26(1), 1-24.

- Scientific Committee on Consumer Safety. (2010). Opinion on Isopropylbenzyl Salicylate. European Commission.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5356801, Isopropylbenzyl Salicylate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Isopropylbenzyl-salicylate

1. Definition Tocopherol:

2. Use:

3. Usage Tocopherol:

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Phenoxyethanol:

2. Use:

3. Usage Phenoxyethanol:

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Methylparaben:

2. Use:

3. Usage Methylparaben:

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report of the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(4), 1-82.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumers Directorate-General.

- Soni, M. G., Carabin, I. G., & Burdock, G. A. (2005). Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and Chemical Toxicology, 43(7), 985-1015.

1. Definition Ethylparaben:

2. Use:

3. Usage Ethylparaben:

4. References:

- SCCS (Scientific Committee on Consumer Safety). (2005). Opinion on Parabens. European Commission.

- Darbre, P. D., & Harvey, P. W. (2008). Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. Journal of Applied Toxicology, 28(5), 561-578.

- FDA (U.S. Food and Drug Administration). (2019). Parabens in Cosmetics. U.S. Department of Health and Human Services.

1. Definition Propylparaben:

2. Use:

3. Usage Propylparaben:

4. References:

- Soni MG, Carabin IG, Burdock GA. Safety assessment of propyl paraben: a review of the published literature. Food Chem Toxicol. 2005;43(7):985-1015. doi:10.1016/j.fct.2005.01.020

- Cosmetic Ingredient Review. Final report on the safety assessment of propylparaben. Int J Toxicol. 2008;27 Suppl 4:1-82. doi:10.1080/10915810802548359

- SCCS (Scientific Committee on Consumer Safety). Opinion on parabens. European Commission. 2011.

1. Definition Butylparaben:

2. Use:

3. Usage Butylparaben:

4. References:

- Darbre, P. D., Aljarrah, A., Miller, W. R., Coldham, N. G., Sauer, M. J., & Pope, G. S. (2004). Concentrations of parabens in human breast tumours. Journal of Applied Toxicology, 24(1), 5-13.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumer Protection Directorate-General.

- Cosmetic Ingredient Review (CIR). (2008). Final report on the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(Suppl 4), 1-82.