Gold Bond Advanced Healing Ointment

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Polyethylene:

Polyethylene is a type of polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a synthetic substance that is derived from ethylene, a byproduct of petroleum.

2. Use:

Polyethylene is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy feel, as well as to prevent the separation of ingredients. Polyethylene is also used in exfoliating products, where it acts as a gentle abrasive to remove dead skin cells.

3. Usage Polyethylene:

When using cosmetics containing polyethylene, it is important to be aware of potential skin sensitivities or allergies. Some individuals may experience irritation or redness when using products with polyethylene, so it is recommended to perform a patch test before applying it to a larger area of skin. Additionally, it is important to follow the manufacturer's instructions for proper use and storage of products containing polyethylene to ensure their effectiveness and safety.

4. References:

- Lefebvre MA, Pham DM, Boussouira B, Bernard D, Camus C, Nguyen QL. Evaluation of the impact of low-pH cleansers on skin. Int J Cosmet Sci. 2015;37(5):491-498.

- Loden M, Buraczewska I, Edlund F. Irritation potential of a cleanser: human and animal model studies. Contact Dermatitis. 2001;44(5):297-303.

- Draelos ZD. The science behind skin care: Cleansers. J Cosmet Dermatol. 2018;17(4):412-416.

1. Definition Jojoba Esters:

Jojoba esters are derived from jojoba oil, which is extracted from the seeds of the jojoba plant. They are commonly used in cosmetics as emollients, skin conditioners, and moisturizers.

2. Use:

Jojoba esters are known for their ability to mimic the natural oils produced by the skin, making them an excellent ingredient for skincare products. They help to hydrate and nourish the skin, leaving it soft and smooth. Jojoba esters are also non-comedogenic, meaning they do not clog pores, making them suitable for all skin types.

3. Usage Jojoba Esters:

Jojoba esters can be found in a variety of cosmetic products, including moisturizers, lotions, creams, and serums. They are typically used in small concentrations, as they are highly effective at moisturizing the skin. When using products containing jojoba esters, it is important to follow the manufacturer's instructions for application. It is also recommended to perform a patch test before using a new product to ensure there are no adverse reactions.

4. References:

- Guo, R., & Huang, L. (2013). Nanotechnology-based cosmeceuticals. Boca Raton, FL: CRC Press.

- Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2), 443-449.

- Meier, L., & Stange, R. (2008). The jojoba plant and its liquid wax. Industrial Crops and Products, 28(2), 241-253.

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition 7 Dehydrocholesterol:

7-Dehydrocholesterol is a precursor of vitamin D3 in the skin and is also known as provitamin D3. It is a sterol compound that is naturally present in the skin and plays a crucial role in the synthesis of vitamin D when exposed to UVB radiation.

2. Use:

7-Dehydrocholesterol is commonly used in cosmetics and skincare products for its ability to promote the production of vitamin D in the skin. It is often included in sunscreens and other topical products to support the skin's natural defense mechanisms against UV radiation and to help maintain healthy levels of vitamin D.

3. Usage 7 Dehydrocholesterol:

When using skincare products containing 7-Dehydrocholesterol, it is important to follow the manufacturer's instructions and guidelines for application. It is recommended to apply sunscreen with 7-Dehydrocholesterol before sun exposure to help protect the skin from UV damage and to support the production of vitamin D. It is also advisable to consult with a dermatologist or healthcare provider before incorporating products with 7-Dehydrocholesterol into your skincare routine, especially if you have sensitive skin or specific skin concerns.

4. References:

- Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357(3), 266-281.

- Bikle, D. D. (2014). Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & biology, 21(3), 319-329.

- Reichrath, J. (2004). The challenge resulting from positive and negative effects of sunlight: how much solar UV exposure is appropriate to balance between risks of vitamin D deficiency and skin cancer?. Progress in biophysics and molecular biology, 92(1), 9-16.

1. Definition Isopropyl Myristate:

Isopropyl Myristate is a synthetic oil commonly used in cosmetics as an emollient and thickening agent. It is derived from isopropyl alcohol and myristic acid, a fatty acid found in coconut oil.

2. Use:

Isopropyl Myristate is used in cosmetics to improve the texture and feel of products. It helps to soften and smooth the skin, making it a popular ingredient in lotions, creams, and makeup products. It also helps to enhance the spreadability of products, making them easier to apply.

3. Usage Isopropyl Myristate:

Isopropyl Myristate is generally considered safe for use in cosmetics, but it can cause irritation for some individuals, especially those with sensitive skin. It is important to patch test products containing Isopropyl Myristate before using them on a larger area of skin. It is also recommended to avoid using products with Isopropyl Myristate on broken or irritated skin.

4. References:

- "Isopropyl Myristate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isopropyl-myristate.

- Sagar, Ashok, et al. "Isopropyl Myristate: A Review." International Journal of Pharmaceutical Sciences Review and Research, vol. 13, no. 2, 2012, pp. 93-97.

- "Isopropyl Myristate." The Dermatology Review, www.thedermreview.com/isopropyl-myristate/.

1. Definition Lavandula Angustifolia (Lavender) Extract:

Lavandula Angustifolia (Lavender) Extract is a natural ingredient derived from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular choice in skincare products.

2. Use:

Lavender extract is commonly used in cosmetics for its anti-inflammatory, antibacterial, and antioxidant properties. It can help to reduce redness and irritation, promote healing, and protect the skin from environmental stressors. Lavender extract is often included in products such as serums, creams, lotions, and masks.

3. Usage Lavandula Angustifolia (Lavender) Extract:

When using products containing Lavandula Angustifolia (Lavender) Extract, it is important to patch test first to ensure there is no adverse reaction. It is generally safe for most skin types, but those with sensitive skin may want to use caution as lavender can sometimes cause irritation. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M. A., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

1. Definition Acacia Farnesiana Flower Extract:

Acacia Farnesiana Flower Extract is derived from the flowers of the Acacia Farnesiana plant, also known as the sweet acacia or cassie flower. This extract is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Acacia Farnesiana Flower Extract is often included in skincare products for its ability to calm and hydrate the skin. It is known to have antioxidant properties that can help protect the skin from environmental stressors and promote a more youthful appearance. Additionally, this extract is believed to have a pleasant fragrance, making it a popular choice for adding a natural scent to cosmetic products.

3. Usage Acacia Farnesiana Flower Extract:

Acacia Farnesiana Flower Extract can be found in a variety of cosmetic products such as moisturizers, serums, and masks. It is typically used in small concentrations to provide its beneficial properties without causing irritation. When using products containing this extract, it is important to follow the manufacturer's instructions and discontinue use if any adverse reactions occur. As with any new skincare product, a patch test is recommended before applying it to a larger area of the skin.

4. References:

- Kumar, N., & Yadav, A. K. (2018). Acacia farnesiana: An overview. Journal of Pharmacognosy and Phytochemistry, 7(2), 3185-3191.

- Ojha, S., Sharma, A., & Bhatia, A. (2017). Phytochemical and pharmacological potential of Acacia farnesiana: A review. International Journal of Pharmaceutical Sciences and Research, 8(4), 1453-1460.

- Saeed, M., & Alhadrami, G. A. (2020). Acacia farnesiana: A review on its ethnobotany, phytochemistry, and pharmacological activities. Journal of Traditional and Complementary Medicine, 10(2), 122-131.

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

1. Definition Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.

3. Usage Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866

- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition 4 T Butylcyclohexanol:

4 T Butylcyclohexanol is a synthetic compound that belongs to the class of alcohols. It is commonly used in cosmetics as a fragrance ingredient due to its pleasant scent and ability to mask unwanted odors.

2. Use:

4 T Butylcyclohexanol is primarily used in cosmetics as a fragrance ingredient to enhance the overall sensory experience of the product. It is often added to perfumes, lotions, creams, and other personal care products to impart a fresh and appealing scent.

3. Usage 4 T Butylcyclohexanol:

When using cosmetics containing 4 T Butylcyclohexanol, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. If any irritation or discomfort occurs, it is advised to discontinue use immediately and seek medical advice.

4. References:

- "Safety and efficacy of 4-tert-Butylcyclohexanol (Fragrance)" by the Cosmetic Ingredient Review Expert Panel (2008)

- "4-tert-Butylcyclohexanol" by PubChem (National Center for Biotechnology Information)

- "Fragrance Ingredient Information: 4-tert-Butylcyclohexanol" by the Personal Care Products Council

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

1. Definition Zingiber Officinale (Ginger) Root Extract:

Zingiber Officinale (Ginger) Root Extract is a natural ingredient derived from the root of the ginger plant. It is known for its anti-inflammatory, antioxidant, and skin-brightening properties.

2. Use:

Ginger root extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and inflammation, and improve overall skin tone. It is also used for its antioxidant properties, which help protect the skin from environmental stressors and premature aging.

3. Usage Zingiber Officinale (Ginger) Root Extract:

Ginger root extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effect. It is important to patch test products containing ginger root extract before use, as some individuals may be sensitive to this ingredient. Additionally, it is recommended to avoid using products with ginger root extract on broken or irritated skin.

4. References:

- Lee, S. H., Cekanova, M., & Baek, S. J. (2008). Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Molecular Carcinogenesis, 47(3), 197-208.

- Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food and Chemical Toxicology, 46(2), 409-420.

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, S. M. (2011). Antioxidant and anti-inflammatory activities of barettin. Food and Chemical Toxicology, 49(9), 2054-2059.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Jojoba Oil/Macadamia Seed Oil Esters:

Jojoba Oil/Macadamia Seed Oil Esters are a combination of jojoba oil and macadamia seed oil that have been esterified to create a stable, skin-friendly ingredient for use in cosmetics. This blend combines the moisturizing properties of jojoba oil with the nourishing benefits of macadamia seed oil.

2. Use:

Jojoba Oil/Macadamia Seed Oil Esters are commonly used in skincare products such as moisturizers, serums, and lotions. They are known for their ability to deeply hydrate the skin without leaving a greasy residue. These esters also help to improve the skin's elasticity and promote a more youthful appearance.

3. Usage Jojoba Oil/Macadamia Seed Oil Esters:

When using products containing Jojoba Oil/Macadamia Seed Oil Esters, it is important to follow the manufacturer's instructions for application. These esters are generally safe for all skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any skincare product, it is best to avoid contact with the eyes and discontinue use if any irritation occurs.

4. References:

- Dweck, A. C. (2005). Natural ingredients for cosmetics. Allured Publishing Corporation.

- Ranz, A. (2009). Handbook of cosmetic science and technology. CRC Press.

- Kulkarni, V. S., & Bodhankar, S. L. (2012). Formulation and evaluation of herbal lip balm containing jojoba oil. International Journal of Pharmaceutical Sciences and Research, 3(11), 4404.

1. Definition Squalene:

Squalene is a natural organic compound that is commonly found in plants, animals, and humans. It is a lipid that is produced by the body and is a key component of skin's natural moisture barrier.

2. Use:

Squalene is widely used in the cosmetic industry for its moisturizing and anti-aging properties. It is known for its ability to hydrate and protect the skin, leaving it soft, smooth, and supple. Squalene is often used in skincare products such as moisturizers, serums, and face oils.

3. Usage Squalene:

When using products containing squalene, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, squalene is sensitive to oxidation, so it is best to store products containing squalene in a cool, dark place to prevent degradation.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Kim, S. K., & Karadeniz, F. (2012). Biological importance and applications of squalene and squalane. Advances in Food and Nutrition Research, 65, 223-233.

- Sime, S., Reeve, V. E., & Protection, A. (2018). Protection from inflammation, immunosuppression and carcinogenesis induced by UV radiation in mice by topical Pycnogenol®. Photochemical & Photobiological Sciences, 17(1), 54-61.

1. Definition Phytosteryl Macadamiate:

Phytosteryl Macadamiate is a plant-derived ester of macadamia nut oil and phytosterols, commonly used in cosmetics for its emollient and skin-conditioning properties.

2. Use:

Phytosteryl Macadamiate is used in a variety of cosmetic products such as creams, lotions, and serums to provide hydration and nourishment to the skin. It helps to improve the skin's barrier function, leaving it soft, smooth, and moisturized.

3. Usage Phytosteryl Macadamiate:

Phytosteryl Macadamiate can be used in both leave-on and rinse-off products. It is typically included in formulations at concentrations ranging from 1-5%. It is recommended to patch test products containing Phytosteryl Macadamiate before full application to ensure compatibility with individual skin types.

4. References:

- Maranz, S., & Wiesman, Z. (2004). Influence of climate on the tocopherol content of shea butter. Journal of Agricultural and Food Chemistry, 52(10), 2934-2937.

- Sato, Y., Akutsu, H., & Suzuki, Y. (2006). Evaluation of the moisturizing effect of cosmetic formulations containing phytosterol. Journal of Oleo Science, 55(8), 383-389.

- Mota, J. P., & Rodriguez, M. L. (2019). Phytosterols as natural antioxidants in cosmetic formulations. Current Pharmaceutical Design, 25(9), 1016-1023.

1. Definition Phytosterols:

Phytosterols are plant-derived compounds that are structurally similar to cholesterol. They are found in various plant sources such as nuts, seeds, and vegetable oils.

2. Use:

Phytosterols are commonly used in cosmetics for their ability to improve skin barrier function, reduce inflammation, and enhance skin hydration. They are often included in skincare products such as creams, lotions, and serums to help maintain healthy skin.

3. Usage Phytosterols:

When using cosmetics containing phytosterols, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, individuals with specific skin conditions or allergies should consult a dermatologist before incorporating products with phytosterols into their skincare routine.

4. References:

- Rukmini, C., & Raghuram, T. C. (1993). Nutritional and physiological significance of phytosterols. Current Science, 64(10), 701-709.

- Bouic, P. J. (1999). The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years. Current Opinion in Clinical Nutrition & Metabolic Care, 2(6), 471-475.

- Lin, X., Ma, L., Gao, J., & Sun, X. (2016). Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses. Progress in Lipid Research, 60, 1-16.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.