Name: Hadalabo Perfect White Tranexamic Acid Cleanser
Brand: Hada Labo
Rating: 5 (6 reviews)

Amino Acid

1. Definition Amino Acids:

Amino acids are organic compounds that serve as the building blocks of proteins. They play a crucial role in various biological processes, including the synthesis of enzymes, hormones, and neurotransmitters.

2. Use:

Amino acids are commonly used in cosmetics for their ability to hydrate, repair, and protect the skin. They can help improve the overall appearance and texture of the skin, as well as promote collagen production and elasticity.

3. Usage Amino Acids:

Amino acids are typically found in skincare products such as serums, creams, and masks. They can be applied topically to the skin, either as standalone products or as part of a formulation with other active ingredients. It is important to follow the instructions on the product label and consult with a dermatologist if you have any concerns about using amino acids in your skincare routine.

4. References:

- Kim, J. E., & Kim, Y. J. (2009). Amino acid derivatives as cosmetic ingredients. Cosmetics & Toiletries, 124(6), 61-68.

- Katsuta, Y., Iida, T., Inomata, S., Denda, M. (2010). Amino acids and skin care: Part 1. Journal of Cosmetic Dermatology, 9(1), 23-29.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic Therapy, 25(3), 252-263.

Arbutin

Other Names: Arbutoside; Arbutine

Function: Skin Conditioning, Antioxidant

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

Vitamin C

Function: Antioxidant, Moisturising, Smoothing, Skin Bleaching Agent

1. Definition Vitamin C:

Vitamin C, also known as ascorbic acid, is a powerful antioxidant that helps to protect the skin from free radicals and environmental damage. It is essential for the production of collagen, which helps to keep the skin firm and youthful-looking.

2. Use:

Vitamin C is commonly used in cosmetics for its brightening and anti-aging properties. It can help to even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and improve the overall texture of the skin. Vitamin C also helps to boost the skin's natural defenses, making it more resilient to environmental stressors.

3. Usage Vitamin C:

Vitamin C can be found in a variety of skincare products, including serums, creams, and masks. It is best applied in the morning, before sunscreen, to help protect the skin from UV damage. When using Vitamin C products, it is important to start with a lower concentration and gradually increase the strength to avoid irritation. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation, which can reduce their effectiveness.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. C. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

Niacinamide

Other Names: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

Hyaluronic Acid

Other Names: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

Hyaluronic Acid Hydrolysis (Nano Hyaluronic Acid)

Ingredient data is being updated. Please check back later.

Glycerin

Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

Sodium Cocoyl Glycinate

Function: Skin Conditioning, Surfactant, Hair Conditioning

1. Definition Sodium Cocoyl Glycinate:

Sodium Cocoyl Glycinate is a mild surfactant derived from coconut oil and the amino acid glycine. It is often used in cosmetic products as a cleansing agent and foaming agent.

2. Use:

Sodium Cocoyl Glycinate is commonly found in skincare products such as cleansers, face washes, and body washes. It helps to remove dirt, oil, and impurities from the skin without stripping away its natural oils. Due to its gentle nature, it is suitable for all skin types, including sensitive skin.

3. Usage Sodium Cocoyl Glycinate:

When using products containing Sodium Cocoyl Glycinate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is lathered onto wet skin, massaged gently, and then rinsed off with water. It is important to avoid getting the product into the eyes, as it may cause irritation. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Cocoyl Glycinate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-cocoyl-glycinate.

- Kumar, Manish, et al. "Sodium Cocoyl Glycinate: An Overview." International Journal of Pharmaceutical Sciences and Research, vol. 11, no. 7, 2020, pp. 3157-3163.

- "Sodium Cocoyl Glycinate." The Derm Review, www.thedermreview.com/sodium-cocoyl-glycinate/.

Butylene Glycol

Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Hydroxypropyl Starch Phosphate

Function: Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent

1. Definition Hydroxypropyl Starch Phosphate:

Hydroxypropyl Starch Phosphate is a modified starch derivative that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from natural starch sources such as corn, wheat, or potatoes and is modified through a chemical process to enhance its performance in cosmetic formulations.

2. Use:

Hydroxypropyl Starch Phosphate is used in cosmetics to improve the texture and consistency of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel to the skin. Additionally, it can help to stabilize emulsions and prevent the separation of oil and water phases in formulations.

3. Usage Hydroxypropyl Starch Phosphate:

When using products containing Hydroxypropyl Starch Phosphate, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient can lead to a sticky or tacky feel on the skin, so it is important to carefully measure and incorporate it into formulations. Additionally, individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure compatibility.

4. References:

- Cosmetics Info. (n.d.). Hydroxypropyl Starch Phosphate. https://cosmeticsinfo.org/ingredient/hydroxypropyl-starch-phosphate

- Personal Care Council. (2019). Hydroxypropyl Starch Phosphate. https://www.personalcarecouncil.org/ingredient-info/hydroxypropyl-starch-phosphate/

- Chemlinked. (2021). Hydroxypropyl Starch Phosphate. https://cosmetic.chemlinked.com/chempedia/hydroxypropyl-starch-phosphate

Cocamidopropyl Betaine

Other Names: Cocoamidopropyl Betaine; Cocoamido propyl Betaine; CAPB; Cocoyl Amide Propyldimethyl Glycine

Function: Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant

1. Definition Cocamidopropyl Betaine:

Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.

2. Use:

Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.

3. Usage Cocamidopropyl Betaine:

When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine

- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/

- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/

PEG-20M

Function: Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent

1. Definition PEG-20M:

PEG-20M, also known as polyethylene glycol 20 monomethyl ether, is a water-soluble polymer that is commonly used in cosmetics as an emollient, surfactant, and skin conditioning agent. It is a type of polyethylene glycol that has a molecular weight of around 20,000 g/mol.

2. Use:

PEG-20M is often used in cosmetic formulations such as creams, lotions, and serums due to its ability to improve the texture and feel of the product on the skin. It helps to hydrate and soften the skin, making it a popular ingredient in moisturizers and anti-aging products. PEG-20M also functions as a surfactant, helping to stabilize and emulsify the ingredients in a formulation.

3. Usage PEG-20M:

When using products containing PEG-20M, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using a product with PEG-20M to ensure they do not have an adverse reaction. It is recommended to avoid using products containing PEG-20M on broken or irritated skin.

4. References:

- Cosmetic Ingredient Review (CIR). (2013). Final report on the safety assessment of PEG-20M. International Journal of Toxicology, 32(4), 1-5.

- Personal Care Products Council. (2008). Safety Assessment of PEG-20M. Cosmetic Ingredient Review Expert Panel.

- Lode, O., & Moos, J. (2005). Polyethylene Glycols. In Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH.

Lauryl Glucoside

Function: Surfactant, Cleansing

1. Definition Lauryl Glucoside:

Lauryl Glucoside is a mild, non-ionic surfactant derived from natural sources such as coconut oil and sugar. It is commonly used in cosmetics and personal care products as a cleansing agent and emulsifier.

2. Use:

Lauryl Glucoside is known for its gentle cleansing properties, making it suitable for use in products designed for sensitive skin. It helps to remove dirt, oil, and impurities from the skin without causing irritation. Additionally, Lauryl Glucoside is often used in hair care products to help create a rich lather and effectively cleanse the scalp and hair.

3. Usage Lauryl Glucoside:

When using products containing Lauryl Glucoside, it is important to follow the instructions provided by the manufacturer. As with any cosmetic ingredient, it is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. While Lauryl Glucoside is considered safe for most individuals, those with extremely sensitive skin may want to consult with a dermatologist before using products containing this ingredient.

4. References:

- "Lauryl Glucoside" - Cosmeticsinfo.org

- "Lauryl Glucoside: A Gentle Surfactant for Sensitive Skin" - The Derm Review

- "Formulating with Lauryl Glucoside" - Personal Care Magazine

Sodium Lauroyl Aspartate

Function: Surfactant, Hair Conditioning, Cleansing

1. Definition Sodium Lauroyl Aspartate:

Sodium Lauroyl Aspartate is a mild surfactant derived from aspartic acid and lauric acid. It is commonly used in cosmetics as a cleansing agent and emulsifier.

2. Use:

Sodium Lauroyl Aspartate is often included in skincare products such as cleansers, shampoos, and body washes due to its gentle cleansing properties. It helps to remove dirt, oil, and impurities from the skin or hair without causing irritation or stripping away natural oils. Additionally, it can help to create a creamy lather and stabilize the formulation of the product.

3. Usage Sodium Lauroyl Aspartate:

When using products containing Sodium Lauroyl Aspartate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to damp skin or hair, massaged gently, and then rinsed off with water. It is generally safe for most skin types, including sensitive skin, but individuals with specific allergies or sensitivities should patch test the product before regular use. It is also important to avoid getting the product in the eyes, as it may cause irritation.

4. References:

- E. Baki, A. Alexander-Katz, and C. R. Mace, “Surfactant structure and composition effects on formation of wormlike micelles in mixed cationic/anionic surfactant systems,” Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 560, pp. 1-9, 2018.

- J. E. Kost, M. J. L. de Jong, and J. C. M. van Hest, “Polymeric micelles for next-generation drug delivery: loading and release of poorly water-soluble drugs,” Journal of Controlled Release, vol. 244, pp. 108-126, 2016.

- S. A. Khan, M. R. Singh, and M. S. Khurana, “The role of surfactants in the formulation of solid dispersions,” Journal of Pharmaceutical Sciences, vol. 107, no. 7, pp. 1733-1750, 2018.

Potassium Cocoyl Glycinate

Function: Surfactant, Hair Conditioning

1. Definition Potassium Cocoyl Glycinate:

Potassium Cocoyl Glycinate is a mild surfactant derived from coconut oil and the amino acid glycine. It is commonly used in cosmetic formulations as a cleansing agent and foaming agent.

2. Use:

Potassium Cocoyl Glycinate is used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation or stripping away natural oils. This ingredient is known for its gentle cleansing properties, making it suitable for sensitive skin types.

3. Usage Potassium Cocoyl Glycinate:

Potassium Cocoyl Glycinate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is water-soluble and can be easily incorporated into a variety of products. When using products containing Potassium Cocoyl Glycinate, it is important to follow the manufacturer's instructions for application and rinse thoroughly with water to remove any residue.

4. References:

- Choi, S. J., Lee, S. H., & Kim, J. Y. (2019). Development of a mild cleansing facial wash using potassium cocoyl glycinate. Journal of Cosmetic Science, 70(3), 193-204.

- Lee, J. H., Kim, J. Y., & Choi, S. J. (2016). Evaluation of the mildness of facial cleansers formulated with potassium cocoyl glycinate. International Journal of Cosmetic Science, 38(3), 244-250.

- Miyake, Y., & Kawai, K. (2017). A study on the properties of potassium cocoyl glycinate as a surfactant for shampoo. Journal of Oleo Science, 66(2), 185-191.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Amino Acid
1	-	Arbutin (Skin Conditioning, Antioxidant)	Good for dry skin Brightening
1	-	Vitamin C (Antioxidant, Moisturising, Smoothing, Skin Bleaching Agent)	Good for dry skin Bad for sensitive skin Bad for oily skin Brightening Moisturizing
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing Moisturizing
-	-	Hyaluronic Acid Hydrolysis (Nano Hyaluronic Acid)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin Moisturizing
1	B	Sodium Cocoyl Glycinate (Skin Conditioning, Surfactant, Hair Conditioning)	Cleansing
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	-	Hydroxypropyl Starch Phosphate (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent)
1 5	B	Cocamidopropyl Betaine (Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant)
3	-	PEG-20M (Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent)
1	B	Lauryl Glucoside (Surfactant, Cleansing)	Cleansing
1	B	Sodium Lauroyl Aspartate (Surfactant, Hair Conditioning, Cleansing)	Cleansing
1	B	Potassium Cocoyl Glycinate (Surfactant, Hair Conditioning)	Cleansing

Hadalabo Perfect White Tranexamic Acid Cleanser

Ingredients

Analysis results of Ingredients

Ingredient List