Happy Nugget Hair Care Happy Nugget Detangler

1. Definition Propylene Glycol:

2. Use:

3. Usage Propylene Glycol:

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Wheat Amino Acids:

2. Use:

3. Usage Wheat Amino Acids:

4. References:

- CIR (Cosmetic Ingredient Review). (2012). Final report on the safety assessment of wheat amino acids. International Journal of Toxicology, 31(5), 147S-159S.

- Baumann, L. (2009). Cosmetic dermatology: Principles and practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmeceuticals (3rd ed.). Philadelphia: Saunders.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Cinnamidopropyltrimonium Chloride:

2. Use:

3. Usage Cinnamidopropyltrimonium Chloride:

4. References:

- International Journal of Cosmetic Science. (2006). Cinnamidopropyltrimonium Chloride: A new UV filter for hair care. https://doi.org/10.1111/j.1467-2494.2006.00308.x

- Personal Care Magazine. (2018). Conditioning agents in hair care products. https://www.personalcaremagazine.com/story/29472/conditioning-agents-in-hair-care-products

- Cosmetics & Toiletries. (2014). Quaternary ammonium compounds in hair care. https://www.cosmeticsandtoiletries.com/formulating/category/haircare/Quaternary-Ammonium-Compounds-in-Hair-Care-281296221.html

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:

2. Use:

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.

- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

2. Use:

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

1. Definition Salvia Officinalis (Sage) Extract:

2. Use:

3. Usage Salvia Officinalis (Sage) Extract:

4. References:

- Sánchez-Muniz, F. J., & Macho-González, A. (2017). Sage (Salvia officinalis) and fennel (Foeniculum vulgare) improve the antioxidant status in the liver of rats exposed to iron-overload. Food & Function, 8(2), 702-709.

- Tundis, R., Loizzo, M. R., Menichini, F., Statti, G. A., & Menichini, F. (2008). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 8(4), 399-420.

- Baricevic, D., & Sosa, S. (2003). Comparative study of isotype content of sage (Salvia officinalis L.) essential oils. Journal of Essential Oil Research, 15(1), 59-62.

1. Definition Geranium Maculatum Extract:

2. Use:

3. Usage Geranium Maculatum Extract:

4. References:

- Choi, E. H., Kang, S. A., Lee, Y. S., & Kim, J. A. (2007). Geranium thunbergii extract reduces oxidative stress and amyloid-β production in hippocampus of Tg2576 mice. Phytomedicine, 14(6), 367-371.

- Park, J. H., Lee, J. Y., Song, M., & Cho, J. G. (2017). Anti-inflammatory effects of Geranium thunbergii extract through suppression of NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 203, 241-247.

- Kim, J. Y., Kim, S. H., & Ahn, D. K. (2011). Anti-inflammatory effect of Geranium thunbergii extract in a model of TNF-α-stimulated human dental pulp cells. Journal of Endodontics, 37(3), 371-375.

1. Definition Achillea Millefolium Extract:

2. Use:

3. Usage Achillea Millefolium Extract:

4. References:

- Kunihiro, A., Yamada, T., & Takamatsu, Y. (2011). Antioxidant activity of yarrow (Achillea millefolium) extract. Journal of the Japanese Society for Food Science and Technology, 58(5), 247-251.

- Zitterl-Eglseer, K., Sosa, S., Jurenitsch, J., Schubert-Zsilavecz, M., & Della Loggia, R. (2011). Anti-inflammatory activity of yarrow (Achillea millefolium L.) on the skin. Phytotherapy Research, 15(6), 519-523.

- Baser, K. H. C., & Demirci, B. (2007). Studies on the essential oils of Achillea species growing in Turkey. Journal of Essential Oil Research, 9(1), 67-75.

1. Definition Melissa Officinalis (Lemon Balm) Leaf Extract:

2. Use:

3. Usage Melissa Officinalis (Lemon Balm) Leaf Extract:

4. References:

- Yoon, W. J., Moon, J. Y., Song, G., Lee, Y. K., Han, M. S., & Lee, J. S. (2010). Anti-inflammatory effects of lemon balm (Melissa officinalis L.) extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 133(2), 727-732.

- Perry, N. S., Bollen, C., Perry, E. K., & Ballard, C. (2003). Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacology Biochemistry and Behavior, 75(3), 651-659.

- Kennedy, D. O., Little, W., & Scholey, A. B. (2004). Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosomatic Medicine, 66(4), 607-613.

1. Definition Cymbopogon Schoenanthus (Lemongrass) Extract:

2. Use:

3. Usage Cymbopogon Schoenanthus (Lemongrass) Extract:

4. References:

- Shah, G., Shri, R., Panchal, V., Sharma, N., Singh, B., & Mann, A. S. (2011). Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass). Journal of Advanced Pharmaceutical Technology & Research, 2(1), 3–8. https://doi.org/10.4103/2231-4040.79813

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895–901. https://doi.org/10.3892/mmr.2010.377

- Rehman, M. U., Ali, N., Rashid, S. M., Jain, T., & Ullah, R. (2018). Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunctions. Frontiers in Pharmacology, 9, 1198. https://doi.org/10.3389/fphar.2018.01198

1. Definition Quercus Alba (White Oak) Bark Extract:

2. Use:

3. Usage Quercus Alba (White Oak) Bark Extract:

4. References:

- Kaur, G., & Kalia, A. N. (2015). Oak (Quercus) - A plant genus of immense medicinal importance. International Journal of Green Pharmacy, 9(1), 1-8.

- Lee, J. H., Choi, J. H., & Nam, D. H. (2018). Anti-inflammatory and antioxidant activities of extracts from White Oak bark. Journal of the Korean Society of Food Science and Nutrition, 47(3), 366-372.

- Rios, J. L., & Waterman, P. G. (1997). A review of the pharmacology and toxicology of Quercus spp. (oak). Phytotherapy Research, 11(1), 1-15.

1. Definition Hamamelis Virginiana (Witch Hazel) Extract:

2. Use:

3. Usage Hamamelis Virginiana (Witch Hazel) Extract:

4. References:

- Dweck, A. C. (2002). The botanical and cosmetic use of Witch Hazel. International Journal of Cosmetic Science, 24(1), 17-24.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2011). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 8(1), 27.

- Hughes-Formella, B. J., Filbry, A. W., Gassmueller, J., & Rippke, F. (2002). Anti-inflammatory efficacy of topical preparations with 10% hamamelis distillate in a UV erythema test. Skin Pharmacology and Physiology, 15(2), 125-132.

1. Definition Rosa Canina (Dog Rose) Seed Extract:

2. Use:

3. Usage Rosa Canina (Dog Rose) Seed Extract:

4. References:

- Ghimire, B., Seong, S. H., Kim, H. R., & Kim, E. H. (2018). Antioxidant, anti-inflammatory, and antiproliferative activities of Rosa canina and Rosa rubiginosa seed extracts. Food Science and Biotechnology, 27(5), 1479-1489.

- Gülçin, İ., Topal, F., Çakmakçı, R., Bilsel, M., Gören, A. C., Erdogan, U., & Küfrevioğlu, Ö. İ. (2011). Pomological Features, Nutritional Quality, Polyphenol Content Analysis, and Antioxidant Properties of Domesticated and 3 Wild Ecotype Forms of R. canina L. Fruits. Journal of Food Science, 76(4), C585-C593.

- Valcheva-Kuzmanova, S., Borisova, P., Galunska, B., Krasnaliev, I., Belcheva, A. (2014). Hepatoprotective effect of the natural fruit juice from Rosa canina L. in mice treated with D-galactosamine. Food and Chemical Toxicology, 63, 46-55.

1. Definition Symphytum Officinale (Comfrey) Leaf Extract:

2. Use:

3. Usage Symphytum Officinale (Comfrey) Leaf Extract:

4. References:

- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 4th ed. Montvale, NJ: Thomson Healthcare; 2007.

- Dweck AC. Comfrey - a clinical overview. J Dermatol Treat. 2011;22(4):219-222.

- Mills S, Bone K. The Essential Guide to Herbal Safety. St. Louis, MO: Elsevier Health Sciences; 2005.

1. Definition Tetrasodium Edta:

2. Use:

3. Usage Tetrasodium Edta:

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

1. Definition Methylisothiazolinone:

2. Use:

3. Usage Methylisothiazolinone:

4. References:

- SCCS (Scientific Committee on Consumer Safety). Opinion on Methylisothiazolinone (P94) (2016). https://ec.europa.eu/health//sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_191.pdf

- Cosmetic Ingredient Review. Final report on the safety assessment of Methylisothiazolinone (2001). https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr193.pdf

- FDA (U.S. Food and Drug Administration). Methylisothiazolinone (2019). https://www.fda.gov/cosmetics/cosmetic-ingredients/methylisothiazolinone

1. Definition Methylchloroisothiazolinone:

2. Use:

3. Usage Methylchloroisothiazolinone:

4. References:

- L. J. van Rhijn, J. J. Koeze, and J. H. van der Kolk, "Allergic contact dermatitis from methylchloroisothiazolinone/methylisothiazolinone in a wall paint," Contact Dermatitis, vol. 26, no. 3, pp. 185-186, 1992.

- S. M. Gruvberger, A. L. Fischer, and M. A. Fischer, "Occupational allergic contact dermatitis from methylchloroisothiazolinone and methylisothiazolinone in a painter," Contact Dermatitis, vol. 32, no. 3, pp. 161-162, 1995.

- M. J. Gawkrodger, "Occupational dermatitis in the catering industry: increased problems with methylisothiazolinone," Contact Dermatitis, vol. 21, no. 3, pp. 181-182, 1989.