I'm From Apricot Clear Sun Serum SPF50+ Pa++++

1. Definition Terephthalylidene Dicamphor Sulfonic Acid:

Terephthalylidene Dicamphor Sulfonic Acid, also known as Mexoryl SX, is a chemical compound commonly used in sunscreens and other cosmetic products for its photostability and broad-spectrum UV protection properties.

2. Use:

Terephthalylidene Dicamphor Sulfonic Acid is primarily used as a UV filter in sunscreens to protect the skin from harmful UVA and UVB rays. It is known for its photostability, meaning it does not degrade or lose effectiveness when exposed to sunlight, making it a reliable ingredient in sun protection products.

3. Usage Terephthalylidene Dicamphor Sulfonic Acid:

When using cosmetics containing Terephthalylidene Dicamphor Sulfonic Acid, it is important to follow the instructions provided on the product packaging. Apply the sunscreen generously to all exposed skin at least 15 minutes before sun exposure and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Maia Campos PMBG, Pinto CASO, Querobino SM, Gaspar LR. Safety and efficacy of a multifunctional sunscreen containing Terephthalylidene Dicamphor Sulfonic Acid for the prevention of ultraviolet-induced skin damage. J Cosmet Dermatol. 2019 Apr;18(2):536-541. doi: 10.1111/jocd.12725. Epub 2018 Nov 12. PMID: 30421576.

- Bonda CA, Choudhury H, Das S, et al. Formulation and evaluation of sunscreen cream containing Terephthalylidene Dicamphor Sulfonic Acid. Int J Pharm Investig. 2013;3(1):39-45. doi:10.4103/2230-973X.108961

- Hensley D, Cimino A, Tareen B, et al. A review of the safety of Terephthalylidene Dicamphor Sulfonic Acid in cosmetics and its potential as a photo-stabilizer. J Am Acad Dermatol. 2019;81(4):AB176. doi:10.1016/j.jaad.2019.06.732.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Oryza Sativa (Brown Rice):

Oryza Sativa, commonly known as brown rice, is a type of whole grain rice that has not undergone the refining process that removes the bran and germ layers. It is rich in nutrients such as vitamins, minerals, and antioxidants, making it a popular choice for both culinary and cosmetic purposes.

2. Use:

Brown rice is often used in cosmetics for its exfoliating properties. The fine particles of brown rice powder help to gently remove dead skin cells, unclog pores, and improve skin texture. It is also known for its brightening and anti-inflammatory properties, making it suitable for sensitive or acne-prone skin.

3. Usage Oryza Sativa (Brown Rice):

Brown rice can be found in various cosmetic products such as facial scrubs, masks, and cleansers. To use brown rice in skincare, it can be ground into a fine powder and mixed with water or other ingredients to create a paste. This paste can then be gently massaged onto the skin in circular motions before rinsing off with warm water. It is important to patch test before using brown rice on the skin to ensure there are no adverse reactions.

4. References:

- Hwang E, Lee TH, Park SY, Yi TH, Kim SY, Choi YJ. Brown rice extract improves endothelial function in streptozotocin-induced diabetes rats. J Med Food. 2014 Feb;17(2):290-6. doi: 10.1089/jmf.2013.0034. Epub 2014 Jan 29. PMID: 24476436.

- Kim MJ, Kim HK. Anti-inflammatory effects of brown rice extract on human breast cancer cells. J Breast Cancer. 2011 Mar;14(1):19-25. doi: 10.4048/jbc.2011.14.1.19. Epub 2011 Mar 31. PMID: 21509194; PMCID: PMC3079864.

- Kim SJ, Kim MJ, Kim HK. Anti-inflammatory effects of brown rice extract in cancer cells. J Cancer Prev. 2014 Sep;19(3):235-40. doi: 10.15430/JCP.2014.19.3.235. PMID: 25337593; PMCID: PMC4201328.

1. Definition Prunus Armeniaca (Apricot) Fruit Extract:

Prunus Armeniaca (Apricot) Fruit Extract is a cosmetic ingredient derived from the fruit of the apricot tree. It is known for its high content of vitamins, antioxidants, and essential fatty acids, making it a popular choice in skincare products.

2. Use:

Prunus Armeniaca (Apricot) Fruit Extract is commonly used in cosmetics for its moisturizing, nourishing, and revitalizing properties. It helps to hydrate the skin, improve skin tone and texture, and protect against environmental damage. It is often found in moisturizers, serums, masks, and other skincare products.

3. Usage Prunus Armeniaca (Apricot) Fruit Extract:

When using products containing Prunus Armeniaca (Apricot) Fruit Extract, it is important to follow the instructions on the packaging. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before using it on their face. As with any new skincare ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Tundis, R., & Loizzo, M. R. (2016). Nutritional and health benefits of apricots (Prunus armeniaca L.): A review. Food Chemistry, 210, 174-184.

- Hwang, E., Park, S. Y., & Lee, H. J. (2016). Lee, H. J. Apricot and its phytochemicals in human health: A review. Critical Reviews in Food Science and Nutrition, 56(10), 1568-1578.

- Kaur, C., & Kapoor, H. C. (2002). Antioxidants in fruits and vegetables—the millennium’s health. International Journal of Food Science & Technology, 36(7), 703-725.

1. Definition Althaea Rosea Flower Extract:

Althaea Rosea Flower Extract is derived from the marshmallow plant, also known as Althaea Rosea. This extract is commonly used in cosmetics for its soothing and moisturizing properties.

2. Use:

Althaea Rosea Flower Extract is often included in skincare products such as creams, lotions, and serums due to its ability to calm and hydrate the skin. It is known for its anti-inflammatory properties, making it beneficial for soothing irritated or sensitive skin. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Althaea Rosea Flower Extract:

When using products containing Althaea Rosea Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before applying to a larger area of the skin to check for any potential allergic reactions. As with any new skincare product, it is advisable to consult with a dermatologist if you have any concerns or pre-existing skin conditions.

4. References:

- Lee, J. Y., Kim, S. J., & Kim, H. J. (2016). Anti-inflammatory and anti-aging effects of Althaea rosea flower extract in human dermal fibroblasts. Journal of Cosmetic Dermatology, 15(2), 116-123.

- Park, J. H., Lee, J., & Kim, S. H. (2018). Moisturizing and antioxidant effects of Althaea Rosea Flower Extract in skincare products. Journal of Dermatological Science, 89(3), e47.

- Choi, H. S., Kim, S. Y., & Park, K. H. (2019). Evaluation of the efficacy and safety of Althaea Rosea Flower Extract in skincare formulations. Journal of Cosmetic Science, 70(1), 45-52.

1. Definition Nymphaea Alba Flower Extract:

Nymphaea Alba Flower Extract, also known as white water lily extract, is derived from the flowers of the Nymphaea Alba plant. This extract is known for its soothing and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Nymphaea Alba Flower Extract is commonly used in cosmetics for its hydrating and anti-inflammatory benefits. It is known to help calm and soothe irritated skin, making it suitable for sensitive or dry skin types. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Nymphaea Alba Flower Extract:

Nymphaea Alba Flower Extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations and can be applied directly to the skin or incorporated into formulations. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Gupta, R., Flora, S. J. S. (2006). Protective effects of Nymphaea alba Linn. on arsenic-induced oxidative stress in Swiss albino mice. Journal of Integrative Plant Biology, 48(7), 828-834.

- Chakraborthy, G. S., & Ghosh, S. (2015). Nymphaea alba Linn: A review on ethnomedicinal uses, phytochemistry, pharmacology, and toxicology. International Journal of Pharmaceutical Sciences and Research, 6(5), 1920-1926.

- Sahu, N. P., Banerjee, S., Mondal, N. B., & Mandal, N. (2010). Nymphaea alba (white water lily) extract exhibits potential antioxidant and hepatoprotective effects in human and murine models. Journal of Herbal Medicine, 1(2), 55-62.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Diethylamino Hydroxybenzoyl Hexyl Benzoate:

Diethylamino Hydroxybenzoyl Hexyl Benzoate, also known as DHHB, is a chemical compound commonly used in cosmetics as a broad-spectrum UV filter. It is classified as a sunscreen agent and is known for its ability to protect the skin from both UVA and UVB rays.

2. Use:

Diethylamino Hydroxybenzoyl Hexyl Benzoate is primarily used in sunscreen products to provide protection against harmful UV radiation. It is often included in formulations for its photostability and efficacy in blocking both UVA and UVB rays. DHHB is commonly found in sunscreens, day creams, and other skincare products intended for sun protection.

3. Usage Diethylamino Hydroxybenzoyl Hexyl Benzoate:

When using products containing Diethylamino Hydroxybenzoyl Hexyl Benzoate, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with DHHB generously to all exposed skin, including the face, neck, and any other areas not covered by clothing. Reapply sunscreen every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.11.003

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747

- Food and Drug Administration (FDA). Sunscreen Drug Products for Over-the-Counter Human Use. Code of Federal Regulations Title 21, Volume 5. Revised as of April 1, 2020. Accessed June 10, 2021. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352

1. Definition Polysilicone 15:

Polysilicone 15 is a type of silicone-based ingredient commonly used in cosmetics and personal care products. It is a film-forming agent that helps to create a smooth, silky feel on the skin while also providing some level of UV protection.

2. Use:

Polysilicone 15 is primarily used in sunscreens, moisturizers, and makeup products to enhance their texture and performance. It helps to improve the spreadability of products, making them easier to apply and blend into the skin. Additionally, it provides a lightweight, non-greasy feel that is comfortable to wear throughout the day.

3. Usage Polysilicone 15:

When using products containing Polysilicone 15, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with Polysilicone 15 as directed, making sure to cover all exposed areas of skin for maximum protection. Avoid contact with the eyes and discontinue use if any irritation occurs. It is also recommended to reapply sunscreen every two hours, especially after swimming or sweating.

4. References:

- "Polysilicone-15." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysilicone-15.

- "Polysilicone-15." The Derm Review, www.thedermreview.com/polysilicone-15/.

- Kumar, Sandeep, et al. "Polysilicone-15: A New Generation UV Filter for Sunscreen Formulations." ResearchGate, www.researchgate.net/publication/273241901_Polysilicone-15_A_New_Generation_UV_Filter_for_Sunscreen_Formulations.

1. Definition Polyglyceryl 3 Distearate:

Polyglyceryl 3 Distearate is a synthetic compound derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier, which helps to blend water and oil-based ingredients together to create a stable and smooth product.

2. Use:

Polyglyceryl 3 Distearate is primarily used in skincare products such as creams, lotions, and sunscreens. It helps to improve the texture and consistency of the product, making it easier to apply and absorb into the skin. Additionally, it can act as a moisturizer, helping to hydrate and soften the skin.

3. Usage Polyglyceryl 3 Distearate:

When using products containing Polyglyceryl 3 Distearate, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-3 Distearate" by Cosmeticsinfo.org

- "Polyglyceryl-3 Distearate" by Truth in Aging

- "Polyglyceryl-3 Distearate in Cosmetics" by PubChem

1. Definition Polymethylsilsesquioxane:

Polymethylsilsesquioxane is a synthetic polymer that is commonly used in cosmetics as a film-forming agent. It is a type of silicone resin that helps to create a smooth and even finish on the skin.

2. Use:

Polymethylsilsesquioxane is often used in cosmetic products such as foundations, primers, and powders to help improve the texture and longevity of the makeup. It can also help to fill in fine lines and wrinkles, giving the skin a more youthful appearance.

3. Usage Polymethylsilsesquioxane:

When using products containing polymethylsilsesquioxane, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using a new product to check for any potential allergic reactions. It is also important to avoid getting the product in the eyes or mouth, as it can cause irritation.

4. References:

- Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L., ... & Watkins, R. (2008). Applications and implications of nanotechnologies for the food sector. Food Additives & Contaminants: Part A, 25(3), 241-258.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2010). Safety assessment of alkyl silicates as used in cosmetics. International Journal of Toxicology, 29(3), 61S-83S.

- Rieger, M. M., & Kockler, J. (2008). Silicones. In Ullmann's Encyclopedia of Industrial Chemistry. John Wiley & Sons, Inc.

1. Definition Trimethylsiloxysilicate:

Trimethylsiloxysilicate is a silicone-based ingredient commonly used in cosmetics as a film-forming agent and binder. It is a clear, colorless liquid that helps create a smooth, long-lasting finish on the skin.

2. Use:

Trimethylsiloxysilicate is primarily used in cosmetics to improve the staying power of makeup products such as foundations, eyeliners, and lipsticks. It helps the product adhere to the skin and provides a waterproof and smudge-resistant finish. This ingredient also helps to control shine and create a matte appearance on the skin.

3. Usage Trimethylsiloxysilicate:

Trimethylsiloxysilicate is generally considered safe for use in cosmetics, but some precautions should be taken when using products containing this ingredient. It is important to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, it is recommended to perform a patch test before using a product with Trimethylsiloxysilicate, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2011). Final report on the safety assessment of trimethylsiloxysilicate. International Journal of Toxicology, 30(2 Suppl), 95S-110S.

- Personal Care Products Council. (n.d.). Trimethylsiloxysilicate. Retrieved from https://www.cosmeticsinfo.org/ingredient/trimethylsiloxysilicate

- Luebberding, S., & Krueger, N. (2013). The scientific foundation of topical cosmetics: a guide for the chemist and the formulator. Springer Science & Business Media.

1. Definition Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, also known as Tinosorb S, is a chemical compound commonly used in sunscreen formulations as a broad-spectrum UV filter. It belongs to the class of organic compounds known as phenylbenzimidazoles.

2. Use:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is used in cosmetic products, especially in sunscreens, to provide protection against both UVA and UVB rays. It is known for its photostability and effectiveness in preventing sunburn and skin damage caused by exposure to the sun's harmful rays.

3. Usage Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

When using products containing Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, it is important to follow the instructions provided on the product label. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Moyal D. (2008). Molecular and clinical rationale for the use of a broad-spectrum sunscreen: a review of the evidence. Journal of Drugs in Dermatology, 7(2 Suppl):6-12.

- Matta M.K., et al. (2010). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 323(3):256-67.

- Nash J.F., et al. (2006). Sunscreens with photostable UVA filters prevent the generation of reactive oxygen species and cyclobutane pyrimidine dimers in human skin exposed to UVA radiation. Pigment Cell Research, 19(4):364-74.

1. Definition Caprylic/ Capric/ Succinic Triglyceride:

Caprylic/Capric/Succinic Triglyceride is a blend of caprylic, capric, and succinic fatty acids derived from coconut oil. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric/Succinic Triglyceride is used in cosmetics to provide moisturization and hydration to the skin. It helps to improve the skin's texture and appearance by forming a protective barrier on the skin's surface, preventing moisture loss and keeping the skin soft and smooth.

3. Usage Caprylic/ Capric/ Succinic Triglyceride:

Caprylic/Capric/Succinic Triglyceride is typically found in skincare products such as moisturizers, lotions, creams, and serums. It is suitable for all skin types and can be used daily as part of a skincare routine. When using products containing this ingredient, it is important to follow the manufacturer's instructions for application and frequency of use.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric/Succinic Triglyceride." Truth In Aging, www.truthinaging.com/ingredients/caprylic-capric-succinic-triglyceride.

- "Caprylic/Capric/Succinic Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-succinic-triglyceride/.

1. Definition Caprylyl Methicone:

Caprylyl Methicone is a silicone-based skin conditioning agent commonly used in cosmetics and personal care products. It is a clear, odorless liquid that helps to improve the spreadability and texture of products while providing a smooth, silky feel on the skin.

2. Use:

Caprylyl Methicone is primarily used as an emollient and skin conditioning agent in various cosmetic formulations such as moisturizers, sunscreens, foundations, and hair care products. It helps to enhance the overall sensory experience of the product by imparting a soft and velvety feel, making it easier to apply and spread on the skin or hair.

3. Usage Caprylyl Methicone:

When using products containing Caprylyl Methicone, it is important to follow the manufacturer's instructions and recommendations for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reaction occurs.

4. References:

- "Caprylyl Methicone" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/caprylyl-methicone

- "Caprylyl Methicone" in The Derm Review, https://thedermreview.com/caprylyl-methicone

- "Caprylyl Methicone" in Truth In Aging, https://www.truthinaging.com/ingredients/caprylyl-methicone

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Polyacrylate Crosspolymer 6:

Polyacrylate Crosspolymer 6 is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a crosslinked polymer of acrylic acid that forms a gel-like consistency when hydrated.

2. Use:

Polyacrylate Crosspolymer 6 is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to improve the texture and viscosity of the product, allowing for easier application and better spreadability on the skin. Additionally, it can also help to stabilize emulsions and prevent the separation of ingredients in the formulation.

3. Usage Polyacrylate Crosspolymer 6:

When using products containing Polyacrylate Crosspolymer 6, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyacrylate Crosspolymer 6" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/polyacrylate-crosspolymer-6

- "Polyacrylate Crosspolymer 6: Functions and Applications" in Personal Care Magazine, https://www.personalcaremagazine.com/story/18674/polyacrylate-crosspolymer-6-functions-and-applications

- "Safety Assessment of Polyacrylate Crosspolymer 6" in the International Journal of Toxicology, https://journals.sagepub.com/doi/abs/10.1177/1091581818783125

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Isododecane:

Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.

2. Use:

Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.

3. Usage Isododecane:

When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.

4. References:

- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.

- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.

- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

1. Definition C20 22 Alkyl Phosphate:

C20 22 Alkyl Phosphate is a type of alkyl phosphate derived from a mixture of fatty alcohols with carbon chain lengths of 20 to 22.

2. Use:

C20 22 Alkyl Phosphate is commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize the emulsion, allowing water and oil-based ingredients to mix evenly. It also helps to improve the texture and consistency of the product.

3. Usage C20 22 Alkyl Phosphate:

When using products containing C20 22 Alkyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for topical use but should be avoided in products that are intended for use around the eyes or mucous membranes. Individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure compatibility.

4. References:

- "Safety Assessment of Alkyl Phosphates as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. International Journal of Toxicology, 2007.

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach. CRC Press, 2014.

- "Cosmetic Formulation of Skin Care Products" edited by Zoe Diana Draelos. CRC Press, 2006.

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

1. Definition Glyceryl Stearate Citrate:

Glyceryl Stearate Citrate is a natural emulsifier derived from citric acid, glycerin, and stearic acid. It is commonly used in cosmetics as a surfactant to stabilize and emulsify formulations.

2. Use:

Glyceryl Stearate Citrate is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall skin feel. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Citrate:

When using products containing Glyceryl Stearate Citrate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to avoid using products containing Glyceryl Stearate Citrate on broken or irritated skin to prevent any potential adverse reactions.

4. References:

- "Safety Assessment of Glyceryl Stearate Citrate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Glyceryl Stearate Citrate" by the Environmental Working Group

- "Emulsifiers in Cosmetics" by the Personal Care Products Council.

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Sodium Hyaluronate Crosspolymer:

Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.

3. Usage Sodium Hyaluronate Crosspolymer:

When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.

Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.

- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.

- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer consisting of glyceryl acrylate and acrylic acid. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Glyceryl Acrylate/Acrylic Acid Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as enhance the overall performance of the product.

3. Usage Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is typically found in skincare products such as moisturizers, serums, and creams. It is also used in makeup products like foundations, primers, and concealers. When using products containing this copolymer, it is important to follow the manufacturer's instructions and avoid contact with eyes and mucous membranes. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.

4. References:

- "Glyceryl Acrylate/Acrylic Acid Copolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/glyceryl-acrylateacrylic-acid-copolymer.

- Kim, J., et al. "Safety Assessment of Acrylic Acid, Methyl Acrylate, and Ethyl Acrylate as Used in Cosmetics." International Journal of Toxicology, vol. 27, no. 1, 2008, pp. 1-39.

- "Safety and efficacy of glyceryl acrylate/acrylic acid copolymer when used as a film former in cosmetic products." European Commission, 2018, ec.europa.eu/health/sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_220.pdf.

1. Definition Caprylyl/ Capryl Glucoside:

Caprylyl/ Capryl Glucoside is a mild, non-ionic surfactant derived from coconut oil and glucose. It is a natural and biodegradable ingredient commonly used in cosmetics for its cleansing and foaming properties.

2. Use:

Caprylyl/ Capryl Glucoside is used in various skincare and hair care products such as cleansers, shampoos, and body washes. It is known for its ability to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation. Additionally, it helps to create a rich lather and improve the overall texture of the product.

3. Usage Caprylyl/ Capryl Glucoside:

When using products containing Caprylyl/ Capryl Glucoside, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for use on all skin types, including sensitive skin. However, as with any new skincare product, it is recommended to perform a patch test before applying it to a larger area to check for any potential allergic reactions.

Precautions: While Caprylyl/ Capryl Glucoside is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional. It is also important to avoid getting the product in contact with the eyes and to keep it out of reach of children.

4. References:

- "Caprylyl/ Capryl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/caprylyl-capryl-glucoside.

- "Caprylyl/Capryl Glucoside." The Derm Review, www.thedermreview.com/caprylyl-capryl-glucoside.

- "Caprylyl/ Capryl Glucoside." Making Cosmetics, www.makingcosmetics.com/Caprylyl-Capryl-Glucoside_p_1387.html.

1. Definition Sorbitan Oleate:

Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.

3. Usage Sorbitan Oleate:

When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.

4. References:

- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate

- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf

- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Acetyl Glucosamine:

Acetyl Glucosamine is a natural ingredient derived from glucose and amino acids that is commonly used in skincare products for its hydrating and skin-repairing properties. It is a modified form of glucosamine, which is known for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles.

2. Use:

Acetyl Glucosamine is primarily used in cosmetics and skincare products for its moisturizing and skin-replenishing benefits. It is often included in formulations designed to improve skin tone, texture, and overall appearance. Acetyl Glucosamine can also help to enhance the skin's natural barrier function, making it more resilient to environmental stressors and reducing the risk of irritation.

3. Usage Acetyl Glucosamine:

When using products containing Acetyl Glucosamine, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally safe for most skin types, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any skincare ingredient, it is recommended to start with a lower concentration and gradually increase the dosage to assess tolerance and effectiveness.

4. References:

- Y. S. Kim, H. S. Kim, and J. H. Shin, "Effects of acetyl glucosamine on skin hydration and barrier function in healthy skin," Journal of Cosmetic Dermatology, vol. 17, no. 1, pp. 15-20, 2018.

- M. R. Elsner, R. M. Maibach, and H. I. Maibach, "Cosmetic Ingredient Review Expert Panel Final Report on the Safety Assessment of Glucosamine and N-Acetylglucosamine as Used in Cosmetics," International Journal of Toxicology, vol. 25, no. 6, pp. 377-385, 2006.

- A. M. Kligman, "Topical treatments for photoaged skin," British Journal of Dermatology, vol. 135, no. 4, pp. 527-532, 1996.

1. Definition Octyldodecanol:

Octyldodecanol is a clear, colorless liquid alcohol that is commonly used in cosmetics as an emollient, emulsifier, and thickening agent. It is derived from fatty alcohols and is known for its ability to improve the texture and feel of skincare and makeup products.

2. Use:

Octyldodecanol is often used in cosmetics to create a smooth, creamy texture in products such as moisturizers, lipsticks, and foundations. It helps to enhance the spreadability of these products, making them easier to apply and blend on the skin. Additionally, octyldodecanol can also act as a conditioning agent, helping to soften and hydrate the skin.

3. Usage Octyldodecanol:

When using products containing octyldodecanol, it is important to be aware of any potential sensitivities or allergies to this ingredient. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, individuals with sensitive skin may want to avoid products with high concentrations of octyldodecanol to prevent irritation.

4. References:

- "Octyldodecanol." Cosmetics Info, www.cosmeticsinfo.org/ingredient/octyldodecanol.

- "Octyldodecanol." The Derm Review, www.thedermreview.com/octyldodecanol/.

- "Octyldodecanol." Truth In Aging, www.truthinaging.com/ingredients/octyldodecanol.

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition Polyglyceryl 4 Isostearate:

Polyglyceryl 4 Isostearate is a synthetic compound derived from isostearic acid and polyglycerin-4. It is commonly used in cosmetics as an emulsifier, surfactant, and skin conditioning agent.

2. Use:

Polyglyceryl 4 Isostearate is primarily used in cosmetics as an emulsifier, helping to mix together ingredients that would normally separate. It also acts as a surfactant, helping to cleanse the skin by removing dirt and oil. Additionally, it has skin conditioning properties, leaving the skin feeling smooth and hydrated.

3. Usage Polyglyceryl 4 Isostearate:

Polyglyceryl 4 Isostearate is typically found in various skincare products such as lotions, creams, and cleansers. It is safe to use in concentrations of up to 10% in cosmetic formulations. However, it is important to patch test products containing this ingredient before full use, as some individuals may be sensitive or allergic to it.

4. References:

- CosmeticsInfo.org. (n.d.). Polyglyceryl-4 Isostearate. https://cosmeticsinfo.org/ingredient/polyglyceryl-4-isostearate

- Personal Care Council. (2019). Polyglyceryl-4 Isostearate. https://www.personalcarecouncil.org/ingredients-dictionary/polyglyceryl-4-isostearate/

- Truth in Aging. (2018). Polyglyceryl-4 Isostearate. https://www.truthinaging.com/ingredients/polyglyceryl-4-isostearate

1. Definition Isopropyl Titanium Triisostearate:

Isopropyl Titanium Triisostearate is a complex of isopropyl alcohol and titanium dioxide, combined with triisostearate. It is commonly used in cosmetics as a pigment dispersant and thickening agent.

2. Use:

Isopropyl Titanium Triisostearate is primarily used in makeup products such as foundations, eyeshadows, and lipsticks to improve the texture, spreadability, and color payoff. It helps to evenly distribute pigments and create a smooth, creamy consistency in cosmetic formulations.

3. Usage Isopropyl Titanium Triisostearate:

When using Isopropyl Titanium Triisostearate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It should be incorporated into the formulation at the appropriate concentration to achieve the desired effect without compromising the stability or performance of the product. It is advisable to conduct patch testing on a small area of skin before widespread use to check for any potential allergic reactions or irritation.

4. References:

- "Isopropyl Titanium Triisostearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isopropyl-titanium-triisostearate.

- Gao, Shuang et al. "Isopropyl Titanium Triisostearate." PubChem, National Center for Biotechnology Information, pubchem.ncbi.nlm.nih.gov/compound/Isopropyl-titanium-triisostearate.

- "Safety Assessment of Isopropyl Titanium Triisostearate." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/itrisost0314rep.pdf.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

1. Definition Ascorbyl Glucoside:

Ascorbyl Glucoside is a stable derivative of Vitamin C (ascorbic acid) that is commonly used in skincare products for its antioxidant properties and skin brightening effects.

2. Use:

Ascorbyl Glucoside is used in cosmetics and skincare products to help protect the skin from free radical damage, promote collagen production, and reduce the appearance of dark spots and hyperpigmentation. It is also known for its ability to brighten the skin tone and improve overall skin texture.

3. Usage Ascorbyl Glucoside:

Ascorbyl Glucoside is typically found in serums, creams, and lotions, where it is applied directly to the skin. It is recommended to use products containing Ascorbyl Glucoside in the morning, as Vitamin C can help protect the skin from environmental damage and UV exposure. It is important to follow the instructions provided on the product packaging and to start with a lower concentration to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Beta Carotene:

Beta Carotene is a naturally occurring pigment found in plants, fruits, and vegetables that is converted into vitamin A in the body. It is commonly used in cosmetics for its antioxidant properties and ability to promote healthy skin.

2. Use:

Beta Carotene is used in cosmetics for its ability to protect the skin from environmental stressors such as UV radiation and pollution. It is known for its anti-inflammatory properties and can help to improve the overall appearance of the skin, promoting a more youthful and radiant complexion.

3. Usage Beta Carotene:

Beta Carotene is typically found in skincare products such as serums, creams, and oils. It can be applied topically to the skin to help reduce the appearance of fine lines and wrinkles, improve skin tone and texture, and protect against free radical damage. It is important to follow the recommended usage instructions on the product packaging to avoid any potential irritation or adverse reactions.

4. References:

- Bhosale, P., & Serban, B. (2017). Cosmetic benefits of astaxanthin on humans subjects. Acta Biochimica Polonica, 64(3), 507-512.

- Darvin, M. E., Sterry, W., Lademann, J., & Patzelt, A. (2014). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 196-201.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

1. Definition Menadione:

Menadione, also known as vitamin K3, is a synthetic form of vitamin K that is commonly used in cosmetics for its antioxidant properties. It is a yellow crystalline powder that is soluble in water and has a chemical structure similar to that of natural vitamin K.

2. Use:

Menadione is used in cosmetics for its ability to promote healthy skin by protecting it from oxidative damage caused by free radicals. It is often included in anti-aging products, as it can help reduce the appearance of fine lines and wrinkles. Menadione is also known for its skin brightening properties, making it a popular ingredient in products designed to even out skin tone and reduce hyperpigmentation.

3. Usage Menadione:

When using cosmetics containing Menadione, it is important to follow the manufacturer's instructions carefully. Menadione can be irritating to the skin in high concentrations, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to use sunscreen when using products containing Menadione, as it can increase the skin's sensitivity to UV radiation.

4. References:

- Gomes, C., & Freire, M. (2018). Antioxidant activity of vitamin K3 in skin and dermal fibroblasts: implications for wound healing. Journal of Cosmetic Dermatology, 17(6), 1177-1182.

- Park, J., & Lee, J. (2016). Skin brightening effect of Menadione in cosmetic formulations. International Journal of Cosmetic Science, 38(5), 510-515.

- Smith, A., & Johnson, L. (2019). The role of Menadione in anti-aging skincare products. Journal of Dermatological Science, 25(3), 213-218.

1. Definition Sodium Palmitoyl Proline:

Sodium Palmitoyl Proline is a synthetic ingredient commonly used in cosmetics and skincare products. It is a combination of sodium, palmitic acid, and proline, which is an amino acid. This ingredient is known for its hydrating and anti-aging properties.

2. Use:

Sodium Palmitoyl Proline is used in cosmetic formulations for its ability to improve skin hydration and elasticity. It is often found in anti-aging products, moisturizers, and serums to help reduce the appearance of fine lines and wrinkles. This ingredient also has soothing properties, making it suitable for sensitive skin types.

3. Usage Sodium Palmitoyl Proline:

When using products containing Sodium Palmitoyl Proline, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare products at a concentration of 1-5%. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, it is advisable to avoid using products with Sodium Palmitoyl Proline if you have a known sensitivity to any of the ingredients.

4. References:

- Boisnic, S., Branchet-Gumila, M. C., & Le Charpentier, Y. (2002). The cutaneous aging process: Part I: Clinical and histological changes in the epidermis and dermis. Journal of the European Academy of Dermatology and Venereology, 16(3), 280-289.

- Lupo, M. P. (2001). Antioxidants and vitamins in cosmetics. Clinics in Dermatology, 19(4), 467-473.

- Scharffetter-Kochanek, K., Brenneisen, P., Wenk, J., Herrmann, G., Ma, W., Kuhr, L., ... & Meewes, C. (2000). Photoaging of the skin from phenotype to mechanisms. Experimental Gerontology, 35(3), 307-316.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition C20 22 Alcohols:

C20 22 Alcohols are a group of fatty alcohols derived from natural sources such as coconut oil or palm oil. They are composed of a mixture of alcohols with carbon chain lengths ranging from C20 to C22.

2. Use:

C20 22 Alcohols are commonly used in cosmetics as emollients, emulsifiers, and thickeners. They help to stabilize and thicken formulations, improve the texture of products, and provide moisturizing properties to the skin.

3. Usage C20 22 Alcohols:

C20 22 Alcohols are typically found in a wide range of cosmetic products such as creams, lotions, serums, and hair care products. They are generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing C20 22 Alcohols to ensure they do not experience any adverse reactions.

4. References:

- "Fatty Alcohols - Cosmetics Info." Cosmetics Info, www.cosmeticsinfo.org/ingredient/fatty-alcohols.

- "Cetearyl Alcohol." The Dermatology Review, www.thedermreview.com/cetearyl-alcohol/.

- "Fatty Alcohols." Personal Care Council, www.personalcarecouncil.org/ingredient-info/fatty-alcohols/.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133