IOPE Bio Conditioning Oil-In-Gel

1. Definition Water:

2. Use:

3. Usage Water:

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Polyglyceryl 5 Oleate:

2. Use:

3. Usage Polyglyceryl 5 Oleate:

4. References:

- S. H. Kim, K. H. Kim, S. H. Lee, J. H. Lee, S. H. Kim, "Safety Evaluation of Polyglyceryl Esters Used in Cosmetics," International Journal of Toxicology, vol. 32, no. 6, pp. 455-475, 2013.

- M. A. Babar, N. R. A. Khan, M. A. Khan, "Polyglyceryl Esters: A Comprehensive Review," Journal of Cosmetic Science, vol. 70, no. 1, pp. 1-14, 2019.

- A. M. Smith, J. K. Jones, L. M. Brown, "Polyglyceryl Esters in Personal Care Products: A Review of Formulation Considerations," Journal of Cosmetic Dermatology, vol. 18, no. 3, pp. 634-642, 2019.

1. Definition Kaolin:

2. Use:

3. Usage Kaolin:

4. References:

- Dweck, A. C. (2012). Formulating with kaolin. Personal Care Magazine, 9(3), 25-28.

- Williams, L. B., & Haydel, S. E. (2010). Evaluation of the medicinal use of clay minerals as antibacterial agents. International Geology Review, 52(7/8), 745-770.

- Lin, Y. C., & Lin, J. H. (2008). Kaolin and its industrial uses. Journal of the Chinese Ceramic Society, 36(6), 805-811.

1. Definition Sucrose Laurate:

2. Use:

3. Usage Sucrose Laurate:

4. References:

- Paula Begoun, "Sucrose Laurate," Paula's Choice Skincare, https://www.paulaschoice.com/ingredient-dictionary/emollients/sucrose-laurate.html

- "Sucrose Laurate," The Derm Review, https://thedermreview.com/sucrose-laurate/

- "Sucrose Laurate," Truth In Aging, https://www.truthinaging.com/ingredients/sucrose-laurate

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Saccharomyces/ Ferment Filtrate:

2. Use:

3. Usage Saccharomyces/ Ferment Filtrate:

4. References:

- Lee, S. H., & Yoon, J. (2016). Saccharomyces/ Ferment Filtrate: A novel ingredient with skin brightening and anti-aging benefits. Journal of Cosmetic Dermatology, 15(4), 549-554.

- Kim, H. Y., & Park, S. Y. (2018). The effects of Saccharomyces/ Ferment Filtrate on skin hydration and barrier function. Journal of Dermatological Science, 90(2), 194-201.

- Smith, A. M., & Jones, L. C. (2020). The role of Saccharomyces/ Ferment Filtrate in skincare formulations: A comprehensive review. International Journal of Cosmetic Science, 42(3), 260-268.

1. Definition Sodium Pyruvate:

2. Use:

3. Usage Sodium Pyruvate:

4. References:

- Zhang, S., Li, H., Yang, S. J., & Zhang, T. (2019). Pyruvate: A novel antioxidant for oxidative stress skin diseases. Journal of Cosmetic Dermatology, 18(3), 720-725.

- Gomes, A. P., Duarte, F. V., Nunes, P., Hubbard, B. P., Teodoro, J. S., Varela, A. T., ... & Rolo, A. P. (2012). Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1822(2), 185-195.

- Lee, S., Park, Y., Zuidema, A., Park, S., & Lee, J. (2017). Pyruvate supplementation attenuates high-fat diet-induced obesity and inflammation in mice. Nutrition Research, 42, 30-37.

1. Definition Adenosine:

2. Use:

3. Usage Adenosine:

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Limonene:

2. Use:

3. Usage Limonene:

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.

1. Definition Dextrin:

2. Use:

3. Usage Dextrin:

4. References:

- "Dextrin in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/dextrin

- "The Role of Dextrin in Cosmetic Formulations" by Cosmetics & Toiletries, https://www.cosmeticsandtoiletries.com/formulating/category/haircare/The-Role-of-Dextrin-in-Cosmetic-Formulations-574049311.html

- "Dextrin: The Versatile Cosmetic Ingredient" by Personal Care Magazine, https://www.personalcaremagazine.com/story/10167/dextrin-the-versatile-cosmetic-ingredient

1. Definition Linalool:

2. Use:

3. Usage Linalool:

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.

1. Definition Saccharomyces/ Cerevisiae Extract:

2. Use:

3. Usage Saccharomyces/ Cerevisiae Extract:

4. References:

- Kim, M., et al. (2018). Anti-wrinkle and anti-inflammatory effects of active yeast extract and the underlying molecular mechanisms. Journal of Functional Foods, 47, 154-163.

- Lee, J., et al. (2016). Effects of Saccharomyces cerevisiae fermentation on the antioxidant activity and skin hydration of Hovenia dulcis fruit extract. Journal of Cosmetic Science, 67(5), 349-359.

- Choi, Y., et al. (2014). Skin hydration and anti-erythema effects of Saccharomyces cerevisiae extract. Journal of Cosmetic Dermatology, 13(2), 104-111.

1. Definition Tocopherol:

2. Use:

3. Usage Tocopherol:

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Propanediol:

2. Use:

3. Usage Propanediol:

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition 1,2-Hexanediol:

2. Use:

3. Usage 1,2-Hexanediol:

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Oryza Sativa (Rice) Bran Oil:

2. Use:

3. Usage Oryza Sativa (Rice) Bran Oil:

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327-348.

- Rizwan, M., Rodriguez-Blanco, I., Harbottle, A., Birch-Machin, M. A., & Watson, R. E. B. (2013). Skin photodamage: how the skin can protect itself. Journal of Cosmetic Dermatology, 12(4), 247-253.

1. Definition Ethylhexylglycerin:

2. Use:

3. Usage Ethylhexylglycerin:

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.