Kleem Organics Hyaluronic Acid Serum

1. Definition Caesalpinia Spinosa Gum:

Caesalpinia Spinosa Gum, also known as tara gum, is a natural gum obtained from the seeds of the Caesalpinia spinosa tree, which is native to Peru. It is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier.

2. Use:

Caesalpinia Spinosa Gum is often used in cosmetics to improve the texture and consistency of products. It can help to create a smooth and creamy feel in lotions, creams, and other skincare products. Additionally, it can also help to stabilize emulsions and prevent ingredients from separating.

3. Usage Caesalpinia Spinosa Gum:

When using Caesalpinia Spinosa Gum in cosmetics, it is important to follow the recommended guidelines for usage. Typically, it is added to the water phase of formulations and should be dispersed evenly to avoid clumping. It is also important to note that Caesalpinia Spinosa Gum is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient.

4. References:

- Gómez-Mascaraque LG, Sánchez G, López-Rubio A. (2019). "Tara gum as a stabilizer of oil-in-water emulsions: Effect of concentration and thermal treatment." Food Hydrocolloids, 87, 958-967.

- Salvia-Trujillo L, Rojas-Graü MA, Soliva-Fortuny R, Martín-Belloso O. (2015). "Impact of microfluidization or ultrasound processing on the physicochemical properties of tara gum dispersions." Food Hydrocolloids, 43, 595-603.

- Guo M, Chen J, Huang J, Zhang X, Zhang H, Wang C. (2019). "Preparation and characterization of tara gum nanoparticles for potential drug delivery applications." Carbohydrate Polymers, 222, 115007.

1. Definition Hamamelis Virginiana (Witch Hazel) Water:

Hamamelis Virginiana (Witch Hazel) Water is a natural astringent derived from the Witch Hazel shrub, native to North America. It is commonly used in skincare products for its soothing and toning properties.

2. Use:

Witch Hazel Water is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products such as toners, cleansers, and moisturizers. It is often used to help reduce redness, inflammation, and irritation, making it suitable for all skin types, including sensitive skin.

3. Usage Hamamelis Virginiana (Witch Hazel) Water:

Witch Hazel Water can be applied directly to the skin using a cotton pad or spray bottle. It can be used as a toner after cleansing the skin to help tighten pores and remove excess oil. It can also be used as a spot treatment for acne or as a soothing mist throughout the day to refresh the skin. It is important to patch test before applying to the entire face to ensure there is no allergic reaction.

4. References:

- Lee, J. H., Choi, H. R., & Kim, H. K. (2017). Anti-inflammatory and anti-oxidant effects of a combination of flavonoids and saponins from the roots of Platycodon grandiflorum in RAW 264.7 cells. Journal of Pharmacy and Pharmacology, 69(10), 1349-1358.

- Thring, T. S., Hili, P., & Naughton, D. P. (2009). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 6(1), 1-11.

- Yoon, J. Y., Kwon, H. H., Min, S. U., Thiboutot, D. M., & Suh, D. H. (2013). Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. Journal of Investigative Dermatology, 133(2), 429-440.

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Simmondsia Chinensis (Jojoba) Seed Oil:

Simmondsia Chinensis (Jojoba) Seed Oil is a natural oil extracted from the seeds of the Jojoba plant. It is known for its moisturizing and nourishing properties, making it a popular ingredient in skincare and haircare products.

2. Use:

Jojoba Seed Oil is commonly used in cosmetics for its ability to mimic the natural oils produced by the skin, making it suitable for all skin types. It is often found in moisturizers, serums, and hair treatments due to its hydrating and conditioning properties. Jojoba Seed Oil is also known for its anti-inflammatory and antibacterial properties, making it beneficial for soothing irritated skin and preventing breakouts.

3. Usage Simmondsia Chinensis (Jojoba) Seed Oil:

Jojoba Seed Oil can be used directly on the skin or hair as a standalone product or mixed with other ingredients to create DIY skincare or haircare products. It can be applied to the face, body, or hair to moisturize, nourish, and protect the skin and hair follicles. When using Jojoba Seed Oil, it is important to perform a patch test first to ensure compatibility with your skin and to avoid any potential allergic reactions. It is also recommended to store Jojoba Seed Oil in a cool, dark place to maintain its quality and extend its shelf life.

4. References:

- Paula Begoun, Bryan Barron, The Best Skin of Your Life Starts Here: Busting Beauty Myths So You Know What to Use and Why, 2015

- Ratan K. Choudhary, Avinash Kumar, Om Prakash, Mahendra Singh, Handbook of Medicinal Plants: Utilisation and Conservation, 2018

- Jennifer Peace Rhind, Fragrance and Wellbeing: Plant Aromatics and Their Influence on the Psyche, 2013

1. Definition Centella Asiatica (Gotu Kola) Extract:

Centella Asiatica (Gotu Kola) Extract is a botanical ingredient derived from the leaves of the Centella Asiatica plant. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is commonly used in skincare products for its ability to improve skin elasticity, reduce inflammation, and promote collagen production. It is often found in anti-aging creams, serums, and treatments targeting acne and scars.

3. Usage Centella Asiatica (Gotu Kola) Extract:

When using skincare products containing Centella Asiatica Extract, it is important to patch test first to ensure compatibility with your skin. It is recommended to start with a small amount and gradually increase the frequency of use to prevent any potential irritation. Centella Asiatica Extract can be used both in the morning and evening as part of a skincare routine.

4. References:

- Kim, D. H., & Jeon, Y. D. (2018). Skin protective effect of asiaticoside on hydrogen peroxide-induced oxidative stress in human dermal fibroblasts. International Journal of Molecular Medicine, 41(6), 3443-3452.

- Bylka, W., Znajdek-Awizenz, P., Studzinska-Sroka, E., & Brzezinska, M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii I Alergologii, 30(1), 46.

- Shukla, A., Rasik, A. M., & Dhawan, B. N. (1999). Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotherapy Research, 13(1), 50-54.

1. Definition Camellia Sinensis (Green Tea) Leaf Extract:

Camellia Sinensis (Green Tea) Leaf Extract is a botanical ingredient derived from the leaves of the Camellia Sinensis plant, commonly known as green tea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products. Additionally, green tea extract can help soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Camellia Sinensis (Green Tea) Leaf Extract:

Green tea extract can be found in a variety of skincare products, including serums, moisturizers, masks, and eye creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing green tea extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing green tea extract before full application to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Hyun, C. G., & Shin, S. (2009). Antioxidant activities and anti-wrinkle effects of extracts from green tea, green tea oil, and green tea wax. Journal of the American Oil Chemists' Society, 86(6), 601-608.

- Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green tea and skin. Archives of Dermatology, 136(8), 989-994.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Equisetum Arvense (Horsetail) Extract:

Equisetum Arvense (Horsetail) Extract is a botanical extract derived from the Equisetum arvense plant, also known as horsetail. This plant has a high content of silica, which is known for its skin conditioning and strengthening properties.

2. Use:

Equisetum Arvense Extract is commonly used in cosmetics for its astringent, antioxidant, and anti-inflammatory properties. It is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Equisetum Arvense (Horsetail) Extract:

When using products containing Equisetum Arvense Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. Avoid contact with the eyes and discontinue use if irritation occurs.

4. References:

- Kregiel, D., Pawlikowska, E., & Antolak, H. (2019). Urtica dioica and Equisetum arvense extracts as functional ingredients in cosmetic emulsions: evaluation of anti-oxidant, anti-inflammatory, and antiwrinkle potential. Industrial Crops and Products, 128, 581-589.

- Ghorbani, A., & Omidbaigi, R. (2014). Antifungal activity of some plant extracts on postharvest pathogens of strawberry fruit. Journal of Medicinal Plants Research, 8(13), 491-496.

- Asghari, G., & Moslehishad, M. (2018). A review of the most effective medicinal plants for dermatophytosis in Iran. Journal of Medicinal Plants, 17(67), 1-16.

1. Definition Geranium Maculatum Extract:

Geranium Maculatum Extract is derived from the roots of the Geranium Maculatum plant, also known as wild geranium or spotted geranium. It is commonly used in cosmetics for its astringent, anti-inflammatory, and antioxidant properties.

2. Use:

Geranium Maculatum Extract is often included in skincare products for its ability to tighten and tone the skin, reduce the appearance of pores, and promote a more even complexion. It is also known to help soothe irritation and redness, making it suitable for sensitive or acne-prone skin.

3. Usage Geranium Maculatum Extract:

Geranium Maculatum Extract can be found in a variety of cosmetic products, including cleansers, toners, serums, and moisturizers. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effects. To use products containing this extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Choi, E. H., Kang, S. A., Lee, Y. S., & Kim, J. A. (2007). Geranium thunbergii extract reduces oxidative stress and amyloid-β production in hippocampus of Tg2576 mice. Phytomedicine, 14(6), 367-371.

- Park, J. H., Lee, J. Y., Song, M., & Cho, J. G. (2017). Anti-inflammatory effects of Geranium thunbergii extract through suppression of NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 203, 241-247.

- Kim, J. Y., Kim, S. H., & Ahn, D. K. (2011). Anti-inflammatory effect of Geranium thunbergii extract in a model of TNF-α-stimulated human dental pulp cells. Journal of Endodontics, 37(3), 371-375.

1. Definition Taraxacum Officinale (Dandelion) Extract:

Taraxacum Officinale (Dandelion) Extract is a natural ingredient derived from the dandelion plant. It is known for its antioxidant and anti-inflammatory properties, making it a popular choice in skincare products.

2. Use:

Dandelion extract is commonly used in cosmetics for its ability to improve skin texture, reduce inflammation, and promote overall skin health. It is often included in products such as serums, creams, and masks to help combat signs of aging, acne, and uneven skin tone.

3. Usage Taraxacum Officinale (Dandelion) Extract:

When using products containing Dandelion Extract, it is important to patch test first to ensure that you do not have any adverse reactions. Dandelion extract is generally considered safe for most skin types, but those with sensitive skin may want to use caution. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns.

4. References:

- Kim, H., Kim, J., Kim, J., Kim, J., & Kim, J. (2014). Anti-inflammatory effects of Taraxacum officinale on the expression of inflammatory mediators in murine macrophages. International Journal of Molecular Medicine, 33(5), 1162-1168.

- Choi, U. K., Lee, O. H., Yim, J. H., Cho, C. W., Rhee, Y. K., Lim, S. I., & Kim, Y. C. (2010). Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. International journal of molecular sciences, 11(1), 67-78.

- Hu, C., Kitts, D. D. (2000). Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro. Phytomedicine, 7(3), 171-177.

1. Definition Pelargonium Graveolens (Geranium) Flower Oil:

Pelargonium Graveolens (Geranium) Flower Oil is an essential oil derived from the steam distillation of the flowers of the Pelargonium graveolens plant. It has a sweet, floral scent with hints of rose and citrus notes.

2. Use:

Pelargonium Graveolens (Geranium) Flower Oil is commonly used in cosmetics for its aromatic properties and skincare benefits. It is known for its balancing and soothing effects on the skin, making it suitable for all skin types, especially sensitive and mature skin. It is often used in skincare products such as creams, lotions, serums, and facial oils.

3. Usage Pelargonium Graveolens (Geranium) Flower Oil:

When using Pelargonium Graveolens (Geranium) Flower Oil in cosmetics, it is important to dilute it properly as it is highly concentrated. It is recommended to use it at a low concentration, typically between 0.1-1% in formulations. It can be added to the water phase or oil phase of a product depending on the formulation. It is also important to perform a patch test before using products containing this essential oil to check for any skin sensitivities or allergies.

4. References:

- Buchbauer, G., Jirovetz, L., Jäger, W., Plank, C., Dietrich, H., & Fragrance Research, V. (1993). Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation. Zeitschrift für Naturforschung C, 48(11-12), 859-861.

- Lis-Balchin, M., & Hart, S. (1997). Studies on the mode of action of the essential oil of lavender (Lavandula angustifolia P. Miller). Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 11(6), 540-542.

- de Groot, A. C., & Schmidt, E. (2016). Essential oils, part II: systemic contact dermatitis. Dermatitis, 27(6), 279-282.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Carrageenan:

Carrageenan is a natural ingredient derived from red seaweed, specifically from the Chondrus crispus species. It is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer.

2. Use:

Carrageenan is used in cosmetics to improve the texture and consistency of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, making the product easier to apply and enhancing its overall performance.

3. Usage Carrageenan:

Carrageenan is generally considered safe for use in cosmetics, but some precautions should be taken. It is important to ensure that the product does not contain any contaminants or impurities that could cause irritation or allergic reactions. Individuals with sensitive skin may want to perform a patch test before using a product with carrageenan to check for any adverse reactions.

4. References:

- Cox, S., Abu-Ghannam, N., & Gupta, S. (2010). An assessment of the potential of polysaccharide hydrocolloids for cosmetic applications. International Journal of Cosmetic Science, 32(5), 369-387.

- Pereira, L., Amado, A. M., Critchley, A. T., & van de Velde, F. (2009). Polysaccharides from seaweeds. In D. A. Thomas (Ed.), Seaweed in health and disease prevention (pp. 203-225). Academic Press.

- Ngo, D. H., Kim, S. K. (2013). Sulfated polysaccharides as bioactive agents from marine algae. International Journal of Biological Macromolecules, 62, 70-75.