La Roche-Posay Anthelios Xl Invisible Mist Spf50+ - Ingredient Explanation
Function: Propellant agent
1. Definition Butane:
Butane is a highly flammable, colorless gas that is commonly used as a propellant in aerosol products, including cosmetics. It is a hydrocarbon with the chemical formula C4H10.
2. Use:
Butane is used in cosmetics to create the pressure necessary to propel products out of aerosol containers, such as hairsprays, deodorants, and shaving creams. It helps to deliver the product in a fine mist or foam form, making it easier to apply evenly.
3. Usage Butane:
When using cosmetics containing butane, it is important to follow the instructions on the product label carefully. It is recommended to use these products in a well-ventilated area, away from sources of heat or flame. Avoid inhaling the gas directly and do not puncture or incinerate the aerosol container. In case of skin irritation or respiratory problems, discontinue use and seek medical attention.
4. References:
- "Butane in Cosmetics: Safety and Regulatory Considerations" by Cosmetic Ingredient Review, 2010.
- "Toxicological Profile for Butane" by Agency for Toxic Substances and Disease Registry, 1997.
- "Butane Safety Data Sheet" by The Linde Group, 2019.
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Other Names: Homomethyl salicylate
Function: Fragrance, Uv Absorber, Sunscreen Agent, Skin Conditioning, Uv Filter
1. Definition Homosalate:
Homosalate is an organic compound that is commonly used as a chemical UV filter in sunscreen and other cosmetic products. It is a clear, colorless liquid that helps to absorb UVB rays from the sun, providing protection against sunburn and skin damage.
2. Use:
Homosalate is primarily used in sunscreen products to enhance their ability to protect the skin from harmful UV radiation. It is often combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays. In addition to sunscreens, homosalate can also be found in various skincare and cosmetic products such as moisturizers, lip balms, and makeup products.
3. Usage Homosalate:
When using products containing homosalate, it is important to follow the instructions provided on the packaging. Apply sunscreen with homosalate generously and evenly to all exposed areas of skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.
4. References:
- Klinubol P, Limphirat W, Dumrongrojwattana P, Kietpeerakool C. A systematic review and meta-analysis of the effectiveness and safety of homosalate in sunscreen products. J Dermatol. 2021;48(12):1682-1690. doi:10.1111/1346-8138.16110
- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747
- Food and Drug Administration (FDA). Sunscreen drug products for over-the-counter human use. Fed Regist. 2019;84(97): 6204-6275.
Other Names: Dioctyl ether
Function: Solvent, Skin Conditioning, Emollient
1. Definition Dicaprylyl Ether:
Dicaprylyl Ether is a clear, colorless liquid that is commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from caprylic acid, a fatty acid found in coconut oil and palm oil.
2. Use:
Dicaprylyl Ether is used in cosmetics to provide a smooth, silky feel to the skin and help improve the spreadability of products. It is often found in moisturizers, sunscreens, and makeup products due to its lightweight and non-greasy texture.
3. Usage Dicaprylyl Ether:
When using products containing Dicaprylyl Ether, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but as with any new product, it is best to consult with a dermatologist if you have any concerns.
4. References:
- "Dicaprylyl Ether" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/dicaprylyl-ether
- "Dicaprylyl Ether" Truth In Aging, https://www.truthinaging.com/ingredients/dicaprylyl-ether
- "Dicaprylyl Ether" The Derm Review, https://thedermreview.com/dicaprylyl-ether/
Other Names: 3-diphenyl acrylate; Octocrylene
Function: Uv Absorber, Sunscreen Agent, Uv Filter
1. Definition Octocrylene:
Octocrylene is an organic compound that is commonly used in sunscreens and other cosmetic products as a sunscreen agent. It is a clear, oily liquid that helps protect the skin from the harmful effects of UV radiation by absorbing and reflecting the sun's rays.
2. Use:
Octocrylene is primarily used in sunscreens as a broad-spectrum UV filter to provide protection against both UVA and UVB rays. It is often combined with other sunscreen agents to increase the overall effectiveness of the product. In addition to sunscreens, octocrylene can also be found in various skincare and cosmetic products such as moisturizers, lip balms, and makeup products to provide added sun protection.
3. Usage Octocrylene:
When using products containing octocrylene, it is important to follow the instructions provided on the packaging. Apply the product generously to all exposed skin at least 15 minutes before sun exposure and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing, seeking shade, and avoiding peak sun hours to further reduce the risk of sun damage.
4. References:
- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.09.003
- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747
- Chatelain E, Gabard B. Photostabilization of butyl methoxydibenzoylmethane (Avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter. Photochem Photobiol. 2001;74(3):401-406. doi:10.1562/0031-8655(2001)074 2.0.CO;2
Other Names: 2-Ethylhexyl Salicylate; Octisalate; Octyl Salicylate
Function: Uv Absorber, Uv Filter
1. Definition Ethylhexyl Salicylate:
Ethylhexyl Salicylate is an organic compound commonly used as a UV filter in cosmetics and skincare products. It is a clear liquid with a faint odor and is derived from salicylic acid.
2. Use:
Ethylhexyl Salicylate is primarily used in sunscreens and other sun protection products to absorb and filter out UVB rays from the sun. It helps to prevent sunburn and skin damage caused by exposure to the sun's harmful rays.
3. Usage Ethylhexyl Salicylate:
Ethylhexyl Salicylate is typically found in sunscreen lotions, creams, and sprays, where it is combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays. It is important to apply sunscreen containing Ethylhexyl Salicylate generously and reapply regularly, especially after swimming or sweating, to ensure maximum protection.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2003). Final report of the safety assessment of ethylhexyl salicylate. International Journal of Toxicology, 22(Suppl 3), 1-35.
- Food and Drug Administration. (2018). Code of Federal Regulations Title 21: Ethylhexyl Salicylate. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=352.10
- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 5352327, Ethylhexyl salicylate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Ethylhexyl-salicylate
Other Names: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000
Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.
2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.
3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.
4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Function: Film Forming, Opacifying
1. Definition Styrene/ Acrylates Copolymer:
Styrene/Acrylates Copolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent. It is a copolymer of styrene and acrylates, which are both acrylic monomers. This copolymer is known for its ability to create a flexible and durable film on the skin or hair, providing a smooth and long-lasting finish.
2. Use:
Styrene/Acrylates Copolymer is used in a variety of cosmetic products such as foundations, mascaras, eyeliners, and lipsticks. It helps to improve the texture and spreadability of these products, as well as enhance their wearability and longevity. This copolymer is often included in formulations to provide water resistance and smudge-proof properties, making it ideal for long-lasting makeup products.
3. Usage Styrene/ Acrylates Copolymer:
When using cosmetics containing Styrene/Acrylates Copolymer, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs.
4. References:
- Zhang, Y., & Wang, J. (2019). Styrene/Acrylates Copolymer. In Handbook of Cosmetic Science and Technology (pp. 421-426). CRC Press.
- Rastogi, S. C., & Heydorn, S. (2006). Acrylic Polymers. In Cosmeceuticals and Active Cosmetics (pp. 93-104). CRC Press.
- Lode, O., & Høgset, A. (2016). Polymer-Based Drug Delivery Systems. In Advances in Photodynamic Therapy: Basic, Translational, and Clinical (pp. 113-143). CRC Press.
Other Names: Avobenzone; Eusolex 9020; Parsol 1789; Avobenzene; Avobezone
Function: Uv Absorber, Uv Filter
1. Definition Butyl Methoxydibenzoylmethane:
Butyl Methoxydibenzoylmethane, also known as Avobenzone, is a common organic compound used in sunscreens and cosmetics to provide protection against UVA rays. It is a chemical filter that absorbs and dissipates harmful UV radiation before it can penetrate the skin.
2. Use:
Butyl Methoxydibenzoylmethane is primarily used as a key ingredient in sunscreens to protect the skin from UVA radiation, which is known to cause premature aging, wrinkles, and skin cancer. It is often combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays.
3. Usage Butyl Methoxydibenzoylmethane:
When using products containing Butyl Methoxydibenzoylmethane, it is important to apply them generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or immediately after swimming or sweating to ensure continued protection. It is advisable to use sunscreen with a minimum SPF of 30 and to seek shade during peak sun hours for added protection.
4. References:
- Kullavanijaya, P., & Lim, H. W. (2005). Photoprotection. Journal of the American Academy of Dermatology, 52(6), 937-958.
- Matta, M. K., Florian, J., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., ... & Stratman, E. J. (2019). Effect of sunscreen application under maximal use conditions on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 321(21), 2082-2091.
- Autier, P., Boniol, M., Dore, J. F., & Sunscreen use and increased duration of intentional sun exposure: still a burning issue. International Journal of Cancer, 121(1), 1-5.
Other Names: Mexoryl XL
Function: Uv Absorber, Uv Filter
1. Definition Drometrizole Trisiloxane:
Drometrizole Trisiloxane is a chemical compound commonly used in cosmetics as a UV filter. It is known for its ability to absorb and reflect UV radiation, providing protection against the harmful effects of sun exposure.
2. Use:
Drometrizole Trisiloxane is primarily used in sunscreens, moisturizers, and other skincare products to enhance their sun protection properties. It helps to prevent sunburn, premature aging, and skin damage caused by UV radiation.
3. Usage Drometrizole Trisiloxane:
When using cosmetics containing Drometrizole Trisiloxane, it is important to follow the instructions provided on the product label. Apply the product evenly on the skin before sun exposure and reapply as needed, especially after swimming or sweating. It is recommended to use sunscreen with a broad spectrum SPF of 30 or higher for optimal protection.
Precautions: While Drometrizole Trisiloxane is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. If any irritation occurs, discontinue use and consult a dermatologist.
4. References:
- European Commission. (2019). CosIng - Cosmetics - GROWTH - European Commission. https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=72212
- Cosmetic Ingredient Review. (2012). Safety Assessment of Drometrizole Trisiloxane as Used in Cosmetics. https://www.cir-safety.org/sites/default/files/drometrizole%20trisiloxane.pdf
- U.S. Food and Drug Administration. (2021). Sunscreen: How to Help Protect Your Skin from the Sun. https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun
Function: Surfactant, Emulsifying
1. Definition Peg 30 Dipolyhydroxystearate:
Peg 30 Dipolyhydroxystearate is a polyethylene glycol derivative of hydroxystearic acid. It is commonly used in cosmetics as an emulsifier and surfactant.
2. Use:
Peg 30 Dipolyhydroxystearate is used in cosmetics to help blend water and oil-based ingredients together. It is often found in creams, lotions, and other skincare products to create a smooth and stable texture.
3. Usage Peg 30 Dipolyhydroxystearate:
When using products containing Peg 30 Dipolyhydroxystearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. Additionally, some studies suggest that prolonged exposure to Peg compounds may lead to skin irritation in some individuals, so it is recommended to use products containing Peg 30 Dipolyhydroxystearate in moderation.
4. References:
- "Safety Assessment of PEG-30 Dipolyhydroxystearate as Used in Cosmetics" Cosmetic Ingredient Review, 2014.
- "PEG-30 Dipolyhydroxystearate" The Environmental Working Group, 2021.
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" American Academy of Dermatology, 2019.
Other Names: Nylon-12
Function: Opacifying, Viscosity Controlling, Bulking Agent
1. Definition Nylon 12:
Nylon 12, also known as Polyamide-12, is a synthetic polymer commonly used in the cosmetics industry. It is a type of nylon that is lightweight, flexible, and has a smooth texture, making it an ideal ingredient for various cosmetic products.
2. Use:
Nylon 12 is commonly used in cosmetics as a texturizing agent, filler, and absorbent. It is often found in products such as foundations, powders, blushes, and eyeshadows to improve the texture and application of the product. Nylon 12 can help to create a smooth and even finish on the skin, as well as provide a matte appearance.
3. Usage Nylon 12:
When using cosmetics containing Nylon 12, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products containing Nylon 12. Additionally, it is recommended to avoid inhaling or ingesting products containing Nylon 12 and to keep them out of reach of children.
4. References:
- L. Leclercq, M. Pelletier, J. L. Leal, L. Rigal, F. J. Wortmann, and M. A. R. Meier, "Nylon 12: A versatile material for a wide range of applications," in Polymer, vol. 40, no. 7, pp. 1863-1875, 1999.
- A. M. J. F. van der Ven, J. R. H. Maas, A. J. Murk, J. J. M. van den Brandhof, and A. C. Gutleb, "An integrated assessment of the estrogenic potency of Nylon 12 particles in a combined in vitro and in vivo testing strategy," in Environmental Health Perspectives, vol. 119, no. 12, pp. 1700-1706, 2011.
- M. R. R. de Oliveira, A. P. A. de Souza, and D. G. Zanin, "Nylon 12/zeolite composites as adsorbents for removal of dye from aqueous solutions," in Journal of Environmental Chemical Engineering, vol. 5, no. 1, pp. 1007-1013, 2017.
Other Names: CETIOL CC
Function: Skin Conditioning, Emollient
1. Definition Dicaprylyl Carbonate:
Dicaprylyl Carbonate is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from caprylic acid, a fatty acid found in coconut oil, and carbonic acid. Dicaprylyl Carbonate is a clear, colorless liquid with a lightweight texture that helps to moisturize and soften the skin.
2. Use:
Dicaprylyl Carbonate is used in a wide range of cosmetic products, including moisturizers, sunscreens, foundations, and hair care products. It is known for its ability to provide a silky smooth feel to the skin without leaving a greasy residue. Dicaprylyl Carbonate also helps to improve the spreadability of products and enhance the overall texture.
3. Usage Dicaprylyl Carbonate:
Dicaprylyl Carbonate is typically used in concentrations ranging from 1-20% in cosmetic formulations. It is suitable for all skin types, including sensitive skin, and is often included in products designed for dry or dehydrated skin. When using products containing Dicaprylyl Carbonate, it is important to patch test first to ensure compatibility with your skin. As with any cosmetic ingredient, discontinue use if irritation occurs.
4. References:
- "Dicaprylyl Carbonate" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/dicaprylyl-carbonate
- "Dicaprylyl Carbonate" The Derm Review, https://thedermreview.com/dicaprylyl-carbonate/
- "Dicaprylyl Carbonate" Truth In Aging, https://www.truthinaging.com/ingredients/dicaprylyl-carbonate
Function: Viscosity Increasing Agent, Film Forming
1. Definition Methyl Methacrylate Crosspolymer:
Methyl Methacrylate Crosspolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and texture enhancer. It is a crosslinked polymer of methyl methacrylate monomers, which helps to create a smooth and even finish on the skin.
2. Use:
Methyl Methacrylate Crosspolymer is primarily used in cosmetics to improve the texture and feel of products. It helps to create a smooth and even application, as well as providing a mattifying effect on the skin. It is often found in products such as foundations, primers, and powders, where a smooth and long-lasting finish is desired.
3. Usage Methyl Methacrylate Crosspolymer:
When using products containing Methyl Methacrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Methyl Methacrylate Crosspolymer. International Journal of Toxicology. 2005;24(Suppl 4):1-13.
- Personal Care Products Council. Methyl Methacrylate Crosspolymer. Accessed online at https://www.personalcarecouncil.org/ingredient/methyl-methacrylate-crosspolymer/.
- Paula's Choice Skincare. Methyl Methacrylate Crosspolymer. Accessed online at https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/methyl-methacrylate-crosspolymer.html.
Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Cyclohexasiloxane:
Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.
2. Use:
Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.
3. Usage Cyclohexasiloxane:
Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.
4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.
- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.
- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.
Other Names: Polymethylsilsequioxane
Function: Opacifying
1. Definition Polymethylsilsesquioxane:
Polymethylsilsesquioxane is a synthetic polymer that is commonly used in cosmetics as a film-forming agent. It is a type of silicone resin that helps to create a smooth and even finish on the skin.
2. Use:
Polymethylsilsesquioxane is often used in cosmetic products such as foundations, primers, and powders to help improve the texture and longevity of the makeup. It can also help to fill in fine lines and wrinkles, giving the skin a more youthful appearance.
3. Usage Polymethylsilsesquioxane:
When using products containing polymethylsilsesquioxane, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using a new product to check for any potential allergic reactions. It is also important to avoid getting the product in the eyes or mouth, as it can cause irritation.
4. References:
- Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L., ... & Watkins, R. (2008). Applications and implications of nanotechnologies for the food sector. Food Additives & Contaminants: Part A, 25(3), 241-258.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2010). Safety assessment of alkyl silicates as used in cosmetics. International Journal of Toxicology, 29(3), 61S-83S.
- Rieger, M. M., & Kockler, J. (2008). Silicones. In Ullmann's Encyclopedia of Industrial Chemistry. John Wiley & Sons, Inc.
Other Names: p-Anisic Acid
Function: Masking, Fragrance, Flavoring Agent
1. Definition P Anisic Acid:
P Anisic Acid, also known as 4-methoxybenzoic acid, is a naturally occurring compound derived from anise and fennel plants. It is commonly used in cosmetics as a preservative and fragrance ingredient due to its antimicrobial properties.
2. Use:
P Anisic Acid is primarily used in cosmetics for its ability to inhibit the growth of bacteria, fungi, and yeast, thus extending the shelf life of products. It is often found in skincare products, such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners.
3. Usage P Anisic Acid:
When using cosmetics containing P Anisic Acid, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for use in skincare and hair care products at concentrations of up to 1%, although some individuals may be sensitive to this ingredient. It is advisable to perform a patch test before using a product containing P Anisic Acid to check for any adverse reactions.
4. References:
- "4-Methoxybenzoic acid" by PubChem, National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Anisic Acid" by Cosmetics Info, The Personal Care Products Council.
- "4-Methoxybenzoic Acid" by Truth In Aging, A Beauty and Wellness Blog.
Other Names: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol
Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Caprylyl Glycol:
Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.
2. Use:
Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.
3. Usage Caprylyl Glycol:
Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.
4. References:
- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017
- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.
- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.
Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na
Function: Chelating Agent, Viscosity Controlling
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.
2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.
3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Function: Viscosity Controlling, Stabilising
1. Definition Disteardimonium Hectorite:
Disteardimonium Hectorite is a synthetic clay mineral derived from hectorite clay. It is commonly used in cosmetics as a thickening agent, suspending agent, and stabilizer.
2. Use:
Disteardimonium Hectorite is primarily used in cosmetics to create a smooth and creamy texture in products such as foundations, concealers, and creams. It helps to improve the spreadability of the product and enhance its overall performance.
3. Usage Disteardimonium Hectorite:
When using products containing Disteardimonium Hectorite, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid inhaling the powder form of Disteardimonium Hectorite to prevent irritation to the respiratory system.
4. References:
- "Safety Assessment of Disteardimonium Hectorite as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Evaluation of the Skin Irritation Potential of Disteardimonium Hectorite" by the Journal of Cosmetic Science
- "Formulation and Characterization of Disteardimonium Hectorite-Based Cosmetic Products" by the International Journal of Cosmetic Science
Function: Solvent, Masking, Fragrance, Viscosity Controlling, Viscosity Decreasing Agent
1. Definition Dodecene:
Dodecene is a type of chemical compound that belongs to the class of alkenes, which are hydrocarbons containing double bonds between carbon atoms. Dodecene specifically refers to a group of isomeric compounds with the chemical formula C12H24.
2. Use:
Dodecene is commonly used in cosmetics as an emollient, solvent, and skin conditioning agent. It is known for its ability to soften and smooth the skin, making it a popular ingredient in moisturizers, lotions, creams, and other skincare products. Dodecene helps to improve the texture of cosmetic formulations and enhance the spreadability of products on the skin.
3. Usage Dodecene:
When using cosmetics containing dodecene, it is important to follow the manufacturer's instructions and guidelines for application. Dodecene is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products containing this ingredient. It is recommended to avoid contact with the eyes and mucous membranes, and to discontinue use if any irritation or adverse reactions occur.
4. References:
- Rao, P. S. S., & Kumar, S. (2019). Dodecene. In Handbook of Ecomaterials (pp. 1-6). Springer, Cham.
- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of dodecene. International Journal of Toxicology, 24(1), 17-32.
- Personal Care Products Council. (2018). Safety Assessment of Dodecene and Dodecene-1 for Use in Cosmetics.
Other Names: Uvinul T 150; Octyl Triazone; 2,4,6‐trianilino‐p‐(carbo‐2‐ethylhexyl‐1‐oxi)‐1,3,5‐triazine
Function: Uv Absorber, Uv Filter
1. Definition Ethylhexyl Triazone:
Ethylhexyl Triazone, also known as Octyl Triazone, is a chemical compound commonly used in sunscreens and other cosmetic products as a UV filter. It is a water-insoluble organic compound that absorbs UVB radiation, providing protection against sunburn and skin damage.
2. Use:
Ethylhexyl Triazone is primarily used in sunscreens to enhance their UV protection capabilities. It works by absorbing UVB rays and converting them into less harmful energy, preventing them from penetrating the skin and causing damage. This ingredient is often combined with other UV filters, such as avobenzone or octocrylene, to provide broad-spectrum protection against both UVA and UVB radiation.
3. Usage Ethylhexyl Triazone:
When using products containing Ethylhexyl Triazone, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours.
4. References:
- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2012.01.001
- Sarveiya V, Risk S, Benson HAE. Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;803(2):225-231. doi:10.1016/j.jchromb.2003.11.032
- Moyal D. Fourcroy P. Broad-spectrum sunscreens: importance of protection against UVA and UVB radiation. J Am Acad Dermatol. 2008;58(5 Suppl 2):S139-S148. doi:10.1016/j.jaad.2007.04.031
Other Names: 2-Methylundecane
Function: Solvent, Perfuming, Fragrance, Emollient
1. Definition Isododecane:
Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.
2. Use:
Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.
3. Usage Isododecane:
When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.
4. References:
- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.
- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.
- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf
Function: Skin Conditioning
1. Definition Lauryl Peg/ Ppg 18/ 18 Methicone:
Lauryl Peg/ Ppg 18/ 18 Methicone is a silicone-based ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to a lauryl group, which helps to improve the texture and feel of cosmetic products.
2. Use:
Lauryl Peg/ Ppg 18/ 18 Methicone is often found in skincare and hair care products such as lotions, creams, serums, and shampoos. It acts as a moisturizer, helping to hydrate and soften the skin or hair, while also providing a smooth and silky finish. Additionally, it can enhance the spreadability of products and improve their overall performance.
3. Usage Lauryl Peg/ Ppg 18/ 18 Methicone:
When using products containing Lauryl Peg/ Ppg 18/ 18 Methicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.
4. References:
- "Safety Assessment of Lauryl Peg/Ppg-18/18 Methicone as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2017)
- "Silicones in Cosmetics" by Gabriella Baki and Kenneth S. Alexander. (2015)
- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach. (2014)
Function: Surfactant, Emulsifying
1. Definition Peg 8 Laurate:
Peg 8 Laurate is a polyethylene glycol ether of lauric acid, which is a fatty acid derived from coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant.
2. Use:
Peg 8 Laurate is used in cosmetic formulations to help mix together ingredients that do not normally combine well, such as oil and water. It helps to stabilize the product, improve its texture, and enhance its overall performance.
3. Usage Peg 8 Laurate:
Peg 8 Laurate is typically found in a wide range of cosmetic products, including lotions, creams, cleansers, and makeup. It is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for concentration levels to avoid any potential irritation or sensitization.
Precautions when using Peg 8 Laurate include conducting a patch test before using a product containing this ingredient, especially if you have sensitive skin. It is also important to follow the instructions provided on the product packaging and consult with a dermatologist if you experience any adverse reactions.
4. References:
- "PEG-8 Laurate" by The Derm Review
- "PEG-8 Laurate" by Truth In Aging
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" by FDA
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Function: Emulsifying, Surfactant
1. Definition Poloxamer 407:
Poloxamer 407, also known as Pluronic F127, is a non-ionic surfactant that is commonly used in the pharmaceutical and cosmetic industries. It is a block copolymer composed of polyethylene oxide and polypropylene oxide, which gives it unique properties such as solubilizing, emulsifying, and stabilizing abilities.
2. Use:
Poloxamer 407 is widely used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to create stable emulsions, improve the texture of products, and enhance the solubility of active ingredients. It is commonly found in creams, lotions, and gels, where it helps to improve the overall performance and appearance of the product.
3. Usage Poloxamer 407:
When using products containing Poloxamer 407, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Poloxamer 407, especially if you have sensitive skin. Additionally, it is important to avoid contact with the eyes and mucous membranes.
4. References:
- Kim, J. W., Lee, J. E., & Kim, J. O. (2019). Development of a cosmetic patch containing poloxamer 407 for skin moisturization. International Journal of Cosmetic Science, 41(2), 167-173.
- Almeida, H., Amaral, M. H., Lobao, P., & Sousa Lobo, J. M. (2017). Applications of poloxamers in ophthalmic pharmaceutical formulations: an overview. Expert Opinion on Drug Delivery, 14(9), 1163-1176.
- Sivakumar, M., Tang, S. Y., Tan, K. W., & Chua, K. H. (2016). Biocompatibility study of poloxamer-based hydrogel as a cell carrier. Biomedical Materials, 11(4), 045006.
Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent
1. Definition Poly C10 30 Alkyl Acrylate:
Poly C10-30 Alkyl Acrylate is a polymer derived from acrylic acid that is commonly used in cosmetics as a film-forming agent and viscosity regulator.
2. Use:
Poly C10-30 Alkyl Acrylate is used in a variety of cosmetics and personal care products such as creams, lotions, and sunscreens. It helps to improve the texture and consistency of these products, giving them a smooth and creamy feel. Additionally, it can also help to increase the longevity of makeup products by forming a film on the skin that helps to lock in moisture and prevent smudging.
3. Usage Poly C10 30 Alkyl Acrylate:
When using products containing Poly C10-30 Alkyl Acrylate, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, it is recommended to discontinue use and consult a dermatologist. Additionally, it is important to store products containing Poly C10-30 Alkyl Acrylate in a cool, dry place away from direct sunlight to maintain their stability and efficacy.
4. References:
- "Poly C10-30 Alkyl Acrylate." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/poly-c10-30-alkyl-acrylate
- "Poly C10-30 Alkyl Acrylate." Truth in Aging, https://www.truthinaging.com/ingredients/poly-c10-30-alkyl-acrylate
- "Poly C10-30 Alkyl Acrylate." The Derm Review, https://www.thedermreview.com/poly-c10-30-alkyl-acrylate/
Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling
1. Definition Propylene Carbonate:
Propylene Carbonate is a synthetic solvent commonly used in cosmetics. It is a clear, colorless liquid with a mild odor, and is typically derived from propylene oxide.
2. Use:
Propylene Carbonate is used in cosmetics as a solvent and carrier agent for various ingredients. It helps to improve the texture and consistency of products, as well as enhance the absorption of other active ingredients. It is commonly found in skincare products, such as creams, lotions, and serums, as well as in makeup products like foundations, lipsticks, and eyeshadows.
3. Usage Propylene Carbonate:
When using products containing Propylene Carbonate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Propylene Carbonate, especially if you have sensitive skin. Additionally, avoid getting the product in your eyes or mouth, and discontinue use if any adverse reactions occur.
4. References:
- "Propylene Carbonate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/propylene-carbonate.
- "Propylene Carbonate." The Dermatology Review, www.thedermreview.com/propylene-carbonate/.
- "Safety Assessment of Propylene Carbonate as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/PCarbonate1114SLR.pdf.
Other Names: NaCl; Natrum muriaticum
Function: Masking, Viscosity Controlling, Bulking Agent
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.
2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.
3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Other Names: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.
2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.
3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Other Names: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume
Function: Masking, Perfuming, Deodorant
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.