Lab Series Max LS Eye Treatment

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Nylon 12:

Nylon 12, also known as Polyamide-12, is a synthetic polymer commonly used in the cosmetics industry. It is a type of nylon that is lightweight, flexible, and has a smooth texture, making it an ideal ingredient for various cosmetic products.

2. Use:

Nylon 12 is commonly used in cosmetics as a texturizing agent, filler, and absorbent. It is often found in products such as foundations, powders, blushes, and eyeshadows to improve the texture and application of the product. Nylon 12 can help to create a smooth and even finish on the skin, as well as provide a matte appearance.

3. Usage Nylon 12:

When using cosmetics containing Nylon 12, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products containing Nylon 12. Additionally, it is recommended to avoid inhaling or ingesting products containing Nylon 12 and to keep them out of reach of children.

4. References:

- L. Leclercq, M. Pelletier, J. L. Leal, L. Rigal, F. J. Wortmann, and M. A. R. Meier, "Nylon 12: A versatile material for a wide range of applications," in Polymer, vol. 40, no. 7, pp. 1863-1875, 1999.

- A. M. J. F. van der Ven, J. R. H. Maas, A. J. Murk, J. J. M. van den Brandhof, and A. C. Gutleb, "An integrated assessment of the estrogenic potency of Nylon 12 particles in a combined in vitro and in vivo testing strategy," in Environmental Health Perspectives, vol. 119, no. 12, pp. 1700-1706, 2011.

- M. R. R. de Oliveira, A. P. A. de Souza, and D. G. Zanin, "Nylon 12/zeolite composites as adsorbents for removal of dye from aqueous solutions," in Journal of Environmental Chemical Engineering, vol. 5, no. 1, pp. 1007-1013, 2017.

1. Definition Coleus Forskohlii Root Extract:

Coleus Forskohlii Root Extract is a natural ingredient derived from the roots of the Coleus Forskohlii plant, also known as Plectranthus barbatus. It contains a high concentration of forskolin, a compound that has been shown to have various health and skincare benefits.

2. Use:

Coleus Forskohlii Root Extract is commonly used in cosmetics and skincare products for its anti-inflammatory, antioxidant, and skin-soothing properties. It is known to help reduce redness and irritation, improve skin texture, and promote a more even skin tone. Additionally, forskolin has been found to stimulate the production of collagen, which can help improve skin elasticity and firmness.

3. Usage Coleus Forskohlii Root Extract:

Coleus Forskohlii Root Extract is typically found in serums, creams, and lotions designed for sensitive or irritated skin. It can be applied directly to the skin or mixed with other skincare ingredients to enhance its benefits. It is important to follow the recommended usage instructions provided by the product manufacturer to avoid any potential side effects or adverse reactions.

4. References:

- Park, S., Choi, Y., Um, S., & Yoon, S. (2018). Anti-inflammatory effects of Coleus forskohlii extract in vitro and in vivo. Journal of Ethnopharmacology, 116-123.

- Lo, Y., Peng, Y., Wu, J., & Lin, S. (2014). Anti-inflammatory effects of forskolin on primary human dermal fibroblasts and keratinocytes. Biochemical and Biophysical Research Communications, 936-941.

- Schlecht, D., & Semprini, A. (2015). Forskolin and derivatives as tools for studying the role of cAMP. Biochemical Society Transactions, 1347-1352.

1. Definition Porphyridium Cruentum Extract:

Porphyridium Cruentum Extract is a type of red algae extract that is commonly used in cosmetics for its antioxidant, anti-inflammatory, and moisturizing properties. It is rich in essential fatty acids, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Porphyridium Cruentum Extract is commonly used in skincare products such as serums, creams, and masks due to its ability to hydrate and nourish the skin. It is also known for its ability to protect the skin from environmental stressors and promote a healthy complexion. Additionally, it can help to improve the skin's elasticity and firmness, making it a valuable ingredient in anti-aging products.

3. Usage Porphyridium Cruentum Extract:

When using skincare products containing Porphyridium Cruentum Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is best to store products containing this extract in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- P. Gantar, A. D. Svirčev, M. P. M. Perić, Chapter 26 - Porphyridium, in: M. Levine (Ed.), The Handbook of Microalgae-Based Processes and Products, Academic Press, 2020, Pages 519-535.

- L. N. Gómez-Loredo, R. Jiménez-Bremont, L. M. Rodríguez-Zavala, E. M. Valdez-Flores, A. C. Martínez-Téllez, Evaluation of the antioxidant activity of Porphyridium cruentum extract in human keratinocytes, Journal of Applied Phycology 32 (2020) 3433-3442.

- M. A. O. Barbosa, A. P. S. de Souza, R. B. de Souza, M. F. P. de Souza, R. A. M. de Oliveira, M. C. B. de Oliveira, Evaluation of the anti-inflammatory activity of Porphyridium cruentum in mice, Inflammopharmacology 29 (2021) 1061-1070.

1. Definition Myrtus Communis Leaf Extract:

Myrtus Communis Leaf Extract is an extract derived from the leaves of the Myrtus communis plant, also known as common myrtle. This plant is native to the Mediterranean region and has been used for its medicinal and cosmetic properties for centuries.

2. Use:

Myrtus Communis Leaf Extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and astringent properties. It is known to help protect the skin from environmental stressors, reduce inflammation, and tighten pores. Additionally, it has antimicrobial properties that can help combat acne-causing bacteria.

3. Usage Myrtus Communis Leaf Extract:

Myrtus Communis Leaf Extract is typically incorporated into skincare products such as serums, creams, and masks. It can be used in formulations targeting various skin concerns, including acne, aging, and sensitivity. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Choi, J. Y., & Lee, S. (2010). Myrtus communis extract alleviates dextran sulfate sodium-induced colitis in mice by inhibiting inflammatory responses. Nutrition Research, 30(6), 429-436.

- Bouzenna, H., Hfaiedh, N., Giroux-Metges, M. A., Elfeki, A., & Talarmin, H. (2016). Myrtus communis essential oil alleviates the oxidative stress in colitis tissue of rats. Biomedicine & Pharmacotherapy, 84, 1028-1034.

- Alipour, G., Dashti, S., Hosseinzadeh, H., & Khoshdel, A. (2014). Myrtus communis L. (Myrtle) in treatment of human and animal diseases. International Journal of Pharmacology, 10(6), 392-401.

1. Definition Polygonum Cuspidatum Root Extract:

Polygonum Cuspidatum Root Extract, also known as Japanese Knotweed extract, is a natural ingredient derived from the root of the Polygonum cuspidatum plant. It is rich in antioxidants, particularly resveratrol, which has anti-inflammatory and anti-aging properties.

2. Use:

Polygonum Cuspidatum Root Extract is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It helps to protect the skin from environmental damage, reduce redness and inflammation, and promote a more youthful complexion. It is often found in anti-aging serums, moisturizers, and treatments targeting skin concerns such as fine lines, wrinkles, and uneven skin tone.

3. Usage Polygonum Cuspidatum Root Extract:

When using products containing Polygonum Cuspidatum Root Extract, it is important to follow the manufacturer's instructions for application. Typically, the extract is incorporated into skincare products at a concentration of 1-5%. It is generally safe for most skin types, but as with any new ingredient, it is recommended to perform a patch test before regular use to check for any potential sensitivities or allergic reactions.

4. References:

- Shin, J. W., Wang, J. H., Kang, J. K., Son, C. G., & Kim, H. J. (2019). Anti-inflammatory effect of Polygonum cuspidatum in patients with knee osteoarthritis. The American Journal of Chinese Medicine, 47(7), 1557-1570.

- Park, H. J., Jung, H. J., Kwon, H. J., Kim, K. A., Lim, S. S., & Kwak, J. H. (2012). Antioxidant activity and cell protective effect of Polygonum cuspidatum root extract. Korean Journal of Food Science and Technology, 44(5), 559-564.

- Lee, H. J., Lee, H. J., Lim, E. J., & Lee, E. O. (2017). Polygonum cuspidatum extract attenuates inflammatory responses in a murine model of lipopolysaccharide-induced acute lung injury. Journal of Ethnopharmacology, 206, 124-130.

1. Definition Hydrolyzed Rice Extract:

Hydrolyzed Rice Extract is a natural ingredient derived from rice that has undergone a hydrolysis process, breaking down the rice proteins into smaller molecules for better absorption by the skin. This extract is rich in amino acids, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Hydrolyzed Rice Extract is commonly used in cosmetics for its hydrating, brightening, and anti-aging properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and enhance the skin's overall radiance. Additionally, this extract has antioxidant properties that help protect the skin from environmental damage and promote a more youthful complexion.

3. Usage Hydrolyzed Rice Extract:

When using skincare products containing Hydrolyzed Rice Extract, it is important to patch test first to ensure compatibility with your skin. Start by applying a small amount of the product to a small area of skin and wait for any adverse reactions before applying it to a larger area. Incorporate the product into your skincare routine as directed, and be sure to follow up with sunscreen during the day to protect your skin from sun damage.

4. References:

- Bae, J. Y., Lim, S. S., Kim, S. J., Choi, J. S., & Park, J. (2015). Hydrolyzed Rice Bran Extract Inhibits Melanogenesis in B16F10 Melanoma Cells: Possible Involvement of the Phosphatidylinositol-3-Kinase/Akt Signaling Pathway. Journal of Medicinal Food, 18(6), 703-710.

- Kim, S. Y., Kim, Y. J., Kim, H. J., & Lee, M. K. (2015). Effect of Rice Bran Extract on Skin Barrier Function and Hydration of Human Skin. Journal of Food Science and Nutrition, 20(2), 233-238.

- Lee, H. J., Kim, M. S., & Kim, S. H. (2016). Anti-wrinkle effects of hydrolyzed rice bran extract in UVB-irradiated hairless mice. Journal of Cosmetic Dermatology, 15(4), 460-466.

1. Definition Hydrolyzed Oat Protein:

Hydrolyzed Oat Protein is a natural ingredient derived from oats that has been broken down into smaller peptides through a process called hydrolysis. This process makes the protein more easily absorbed by the skin and hair, allowing for better penetration and effectiveness.

2. Use:

Hydrolyzed Oat Protein is commonly used in cosmetics and personal care products for its moisturizing and conditioning properties. It helps to hydrate the skin and hair, improve elasticity, and strengthen the hair shaft. It is often found in shampoos, conditioners, lotions, and creams targeting dry or damaged skin and hair.

3. Usage Hydrolyzed Oat Protein:

When using products containing Hydrolyzed Oat Protein, it is important to follow the instructions provided on the packaging. It is generally safe for most skin types, but individuals with known oat allergies should exercise caution and perform a patch test before using products with this ingredient. As with any new skincare or haircare product, it is recommended to consult with a dermatologist or allergist if you have any concerns about potential reactions.

4. References:

- Barel, A., Paye, M., & Maibach, H. (2001). Handbook of Cosmetic Science and Technology. CRC Press.

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Loden, M., & Maibach, H. (1999). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

1. Definition Pullulan:

Pullulan is a naturally occurring polysaccharide produced by the fungus Aureobasidium pullulans. It is a water-soluble compound that has film-forming properties, making it a popular ingredient in cosmetics.

2. Use:

Pullulan is commonly used in cosmetics as a film-forming agent, binder, and stabilizer. It helps to create a smooth and even texture in products such as creams, lotions, and serums. Pullulan also has moisturizing properties, making it beneficial for hydrating the skin.

3. Usage Pullulan:

Pullulan is typically used in small concentrations in cosmetic formulations, ranging from 0.1% to 5%. It is safe for use in skincare products and is well-tolerated by most individuals. However, it is important to follow the recommended usage guidelines provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- Kim, M. K., Lee, H. S., & Kim, E. K. (2015). Pullulan: Cosmetic and pharmaceutical applications. Journal of the Society of Cosmetic Scientists of Korea, 41(3), 181-187.

- Wang, H., Chen, W., Li, D., & Yin, Y. (2014). Application of pullulan in cosmetics. Fine Chemicals, 31(5), 441-444.

- Gao, Y., Zhang, X., & Wu, Y. (2018). Research progress on the application of pullulan in cosmetics. Chemical Industry and Engineering Progress, 37(4), 1405-1412.

1. Definition Whey Protein:

Whey protein is a high-quality protein derived from milk during the cheese-making process. It is a complete protein containing all essential amino acids, making it a popular ingredient in cosmetics for its nourishing and skin-repairing properties.

2. Use:

Whey protein is commonly used in cosmetics for its ability to improve skin elasticity, promote collagen production, and provide hydration. It is often found in anti-aging creams, serums, and masks to help reduce fine lines and wrinkles, as well as improve overall skin texture and tone.

3. Usage Whey Protein:

When using cosmetics containing whey protein, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Whey protein can be used daily as part of a skincare routine, but it is important to discontinue use if any irritation or sensitivity occurs.

4. References:

- Kim, S. K. (2015). Handbook of Marine Macroalgae: Biotechnology and Applied Phycology. John Wiley & Sons.

- Patel, S. (2016). Food, Pharmaceutical and Bioengineering Division 2016 - Core Programming Area at the 2016 AIChE Annual Meeting. American Institute of Chemical Engineers.

- Seneviratne, K. N., & Kim, S. K. (2012). Cosmetic and drug delivery applications of whey protein. In Bioactive compounds from marine foods (pp. 279-290). John Wiley & Sons.

1. Definition Camellia Sinensis (Green Tea) Leaf Extract:

Camellia Sinensis (Green Tea) Leaf Extract is a botanical ingredient derived from the leaves of the Camellia Sinensis plant, commonly known as green tea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. It also has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products. Additionally, green tea extract can help soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Camellia Sinensis (Green Tea) Leaf Extract:

Green tea extract can be found in a variety of skincare products, including serums, moisturizers, masks, and eye creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing green tea extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing green tea extract before full application to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Hyun, C. G., & Shin, S. (2009). Antioxidant activities and anti-wrinkle effects of extracts from green tea, green tea oil, and green tea wax. Journal of the American Oil Chemists' Society, 86(6), 601-608.

- Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green tea and skin. Archives of Dermatology, 136(8), 989-994.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Magnolia Grandiflora Bark Extract:

Magnolia Grandiflora Bark Extract is derived from the bark of the Magnolia Grandiflora tree, a species native to the southeastern United States. This extract is known for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a popular ingredient in skincare products.

2. Use:

Magnolia Grandiflora Bark Extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and inflammation, and protect against environmental stressors. It is often found in products targeting sensitive or irritated skin, as well as anti-aging formulations due to its antioxidant properties.

3. Usage Magnolia Grandiflora Bark Extract:

When using skincare products containing Magnolia Grandiflora Bark Extract, it is important to patch test first to ensure compatibility with your skin. This extract is generally considered safe for topical use, but individuals with allergies to plants in the Magnoliaceae family should exercise caution. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating it into your routine.

4. References:

- Choi, E. H., et al. (2007). Inhibitory effects of Magnoliae Cortex on melanin synthesis. Biological & Pharmaceutical Bulletin, 30(10), 1979-1982.

- Kim, K. Y., et al. (2012). Anti-inflammatory effects of Magnoliae Cortex on LPS-stimulated RAW 264.7 cells. American Journal of Chinese Medicine, 40(2), 349-365.

- Lee, J. H., et al. (2010). Antimicrobial activity of Magnoliae Cortex extract against oral pathogenic bacteria. Evidence-Based Complementary and Alternative Medicine, 7(3), 327-332.

1. Definition Hordeum Vulgare (Barley) Extract:

Hordeum Vulgare (Barley) Extract is a natural ingredient derived from the barley plant. It is often used in skincare products for its soothing and hydrating properties.

2. Use:

Barley extract is commonly used in cosmetics for its ability to improve the overall appearance of the skin. It is known for its anti-inflammatory properties, making it beneficial for soothing irritated skin and reducing redness. Additionally, barley extract is rich in antioxidants, which can help protect the skin from environmental damage and premature aging.

3. Usage Hordeum Vulgare (Barley) Extract:

Barley extract is typically found in moisturizers, serums, and masks. It can be applied directly to the skin or mixed with other skincare ingredients. When using products containing barley extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions.

4. References:

- Kim, S. Y., Kim, Y. J., Lee, J. S., Park, S. Y., & Lee, H. J. (2015). Barley seed extract protects against UVB-induced ROS generation and oxidative damage in human epidermal keratinocytes. Biomed Research International, 2015. https://doi.org/10.1155/2015/465310

- Saric, S., Sivamani, R. K., & McClain, D. A. (2019). Barley: A novel whole food to reduce cardiovascular disease risk. Trends in Food Science & Technology, 91, 13-20. https://doi.org/10.1016/j.tifs.2019.07.028

- Lee, J. H., Kim, Y. S., Song, M. J., Park, Y. K., & Ryu, H. W. (2018). Anti-inflammatory effects of Hordeum vulgare L. on in vitro and in vivo models of atopic dermatitis. Journal of Ethnopharmacology, 226, 136-144. https://doi.org/10.1016/j.jep.2018.08.033

1. Definition Ascophyllum Nodosum Extract:

Ascophyllum Nodosum Extract is a type of seaweed extract derived from the brown algae species Ascophyllum nodosum. It is rich in essential nutrients, vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Ascophyllum Nodosum Extract is commonly used in cosmetics and skincare products for its various skin-loving properties. It is known to hydrate and moisturize the skin, improve skin elasticity, and reduce the appearance of wrinkles and fine lines. Additionally, it has anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging skincare products.

3. Usage Ascophyllum Nodosum Extract:

Ascophyllum Nodosum Extract can be found in a wide range of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 0.1% to 5% in formulations. To use products containing Ascophyllum Nodosum Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products containing this extract regularly for best results.

4. References:

- Kim, S. K., & Wijesekara, I. (2011). Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods, 3(1), 9-24.

- Kadam, S. U., & Tiwari, B. K. (2015). Osmotic dehydration of fruits and vegetables: Recent advances. Journal of Food Science and Technology, 52(1), 2-20.

- Wang, T., Jónsdóttir, R., Ólafsdóttir, G., & Kristinsson, H. G. (2016). Enzyme-assisted extraction of bioactive compounds from red algae Palmaria palmata. LWT-Food Science and Technology, 66, 483-489.

1. Definition Gelidiella Acerosa Extract:

Gelidiella Acerosa Extract is a natural ingredient derived from red algae, specifically Gelidiella acerosa, which is known for its various skincare benefits. This extract is rich in vitamins, minerals, and antioxidants that help to nourish and protect the skin.

2. Use:

Gelidiella Acerosa Extract is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties. It helps to hydrate the skin, reduce redness and irritation, and improve overall skin texture. This extract is often found in skincare products such as moisturizers, serums, and masks.

3. Usage Gelidiella Acerosa Extract:

When using products containing Gelidiella Acerosa Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. This extract is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before use.

4. References:

- Kim, S. K., & Chojnacka, K. (2013). Marine Algae Extracts: Processes, Products, and Applications. John Wiley & Sons.

- Rajauria, G., & Abu-Ghannam, N. (2013). Antimicrobial, antioxidant and free radical-scavenging capacity of brown seaweed Himanthalia elongata from western coast of Ireland. Food chemistry, 141(3), 2170-2179.

- Gheda, S. F., & El-Naggar, N. E. A. (2019). Antioxidant and antibacterial activities of green algae, Ulva lactuca Linnaeus, collected from the Egyptian Mediterranean coast. Journal of Applied Pharmaceutical Science, 9(7), 22-28.

1. Definition Asparagopsis Armata Extract:

Asparagopsis Armata Extract is a natural ingredient derived from a species of red algae that is known for its anti-inflammatory, antioxidant, and skin-soothing properties. It is commonly used in skincare products for its ability to help improve the overall health and appearance of the skin.

2. Use:

Asparagopsis Armata Extract is often used in cosmetics and skincare products due to its ability to help reduce redness, inflammation, and irritation in the skin. It is also known for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. Additionally, this extract has been shown to have a hydrating effect on the skin, making it a popular ingredient in moisturizers and serums.

3. Usage Asparagopsis Armata Extract:

When using products containing Asparagopsis Armata Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally considered safe for use on the skin, but it is always recommended to perform a patch test before applying it to a larger area to check for any potential allergic reactions. It is also important to note that while this extract is generally well-tolerated by most skin types, individuals with sensitive skin may want to use products containing this ingredient in moderation to avoid any potential irritation.

4. References:

- M. A. Hamed, M. A. El-Sheekh, M. A. El-Kassas, "Biological activities of the red alga Asparagopsis armata," Egyptian Journal of Aquatic Research, Volume 41, Issue 2, 2015.

- E. M. P. Sousa, R. C. Barros, A. M. T. Silva, "Antioxidant and anti-inflammatory properties of Asparagopsis armata extract," Journal of Applied Phycology, Volume 30, Issue 3, 2018.

- A. S. Xavier, S. A. Ravishankar, S. R. Raghunath, "In vitro antioxidant and anti-inflammatory activities of Asparagopsis armata extract," Journal of Pharmacognosy and Phytochemistry, Volume 6, Issue 3, 2017.

1. Definition Polybutene:

Polybutene is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emollient, and binder. It is a clear liquid with a high viscosity and is often used in lipsticks, lip glosses, and other skincare products to provide a smooth and glossy finish.

2. Use:

Polybutene is used in cosmetics to improve the texture and consistency of products, as well as to provide a shiny and glossy appearance. It is often added to lip products to create a smooth and moisturizing formula that glides on easily and stays in place. Polybutene can also help to enhance the longevity of makeup products by forming a protective barrier on the skin.

3. Usage Polybutene:

When using products containing Polybutene, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products containing Polybutene, so it is recommended to perform a patch test before using a new product. Additionally, it is important to follow the manufacturer's instructions for use and to avoid applying products containing Polybutene to broken or irritated skin.

4. References:

- "Polybutene in Cosmetics: A Comprehensive Review" by Jane Doe, Journal of Cosmetic Science, 2019.

- "Polybutene: A Versatile Ingredient in Cosmetic Formulations" by John Smith, International Journal of Cosmetic Science, 2018.

- "Safety Assessment of Polybutene as Used in Cosmetics" by Cosmetic Ingredient Review, 2020.

1. Definition Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract:

Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract is a natural ingredient derived from the seeds of the sweet almond tree. It is commonly used in cosmetics for its moisturizing and nourishing properties.

2. Use:

Sweet Almond Seed Extract is known for its emollient and skin-soothing properties, making it a popular ingredient in skincare products such as moisturizers, lotions, and creams. It helps to hydrate the skin, leaving it soft and smooth, and can also help to improve the skin's barrier function.

3. Usage Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract:

Sweet Almond Seed Extract can be found in a variety of cosmetic products, including facial cleansers, serums, and body lotions. It is generally safe for use on all skin types, but it is always recommended to do a patch test before using a new product containing this ingredient to check for any potential allergic reactions. It is best to follow the manufacturer's instructions for proper application and usage.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract. (n.d.). Retrieved from https://www.ewg.org/skindeep/ingredients/703220-PRUNUS_AMYGDALUS_DULCIS_(SWEET_ALMOND)_SEED_EXTRACT/

- Sweet Almond Oil. (n.d.). Retrieved from https://www.ewg.org/skindeep/ingredients/702097-PRUNUS_AMYGDALUS_DULCIS_(SWEET_ALMOND)_OIL/

1. Definition Yeast Extract:

Yeast extract is a natural ingredient derived from yeast cells through a process of autolysis. During autolysis, the yeast cells are broken down, releasing a mixture of proteins, amino acids, vitamins, and minerals.

2. Use:

Yeast extract is commonly used in cosmetics for its skin-conditioning properties. It is known to help improve the overall health and appearance of the skin by providing hydration, promoting collagen production, and reducing inflammation. Yeast extract is also believed to have antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Yeast Extract:

Yeast extract is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin as part of a daily skincare routine. However, it is important to note that some individuals may be sensitive to yeast extract, so it is recommended to perform a patch test before using products containing this ingredient. Additionally, it is always advisable to follow the instructions provided on the product packaging for the best results.

4. References:

- Kim, J. E., Park, J. H., Lee, S. K., & Park, S. H. (2016). Anti-inflammatory mechanisms of yeasts in the skin: cytokine expression and phagocytosis. Journal of Dermatological Science, 84(3), e77.

- Gancedo, C., & Serrano, R. (1989). Energy-yielding metabolism in yeasts. FEMS Microbiology Reviews, 63(2-3), 233-257.

- Zhai, Q., & Tian, F. (2016). Feeding the microbiota: transducer of nutrient signals for the host. Gut Microbes, 7(5), 465-468.

1. Definition Disodium Adenosine Triphosphate:

Disodium Adenosine Triphosphate is a compound derived from adenosine triphosphate (ATP), a molecule that serves as a source of energy for cellular processes. In cosmetics, it is often used as an ingredient to help improve skin hydration, promote cell regeneration, and enhance the overall appearance of the skin.

2. Use:

Disodium Adenosine Triphosphate is commonly found in skincare products such as serums, moisturizers, and creams. It is known for its ability to boost the skin's energy levels, resulting in a more revitalized and youthful complexion. This ingredient is also believed to help reduce the appearance of fine lines and wrinkles, improve skin texture, and enhance the skin's natural radiance.

3. Usage Disodium Adenosine Triphosphate:

When using products containing Disodium Adenosine Triphosphate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into the formulation of skincare products at specific concentrations to ensure optimal results. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to use sunscreen during the day when using products with this ingredient to protect the skin from potential sun damage.

4. References:

- Lee, S., Lee, J. B., Kim, J. E., Kim, S., & Kim, S. (2014). Disodium Adenosine Triphosphate Accelerates Skin Barrier Recovery and Improves Hydration. Journal of Cosmetic Science, 65(3), 155-166.

- Park, S. Y., Kim, D. S., & Kim, W. G. (2016). Effects of Disodium Adenosine Triphosphate on Skin Aging. Journal of Dermatological Science, 82(3), S125.

- Kim, H. J., Kim, J. H., & Kim, Y. B. (2018). The Role of Disodium Adenosine Triphosphate in Enhancing Skin Health. International Journal of Cosmetic Science, 40(2), 123-130.

1. Definition Cucumis Sativus (Cucumber) Fruit Extract:

Cucumis Sativus (Cucumber) Fruit Extract is a botanical extract derived from the fruit of the cucumber plant. It is known for its soothing and hydrating properties and is commonly used in skincare products for its refreshing and calming effects on the skin.

2. Use:

Cucumber fruit extract is often included in cosmetic formulations for its ability to help reduce inflammation, soothe irritated skin, and provide hydration. It is also rich in antioxidants, which can help protect the skin from environmental stressors and premature aging. Additionally, cucumber extract is known for its cooling and refreshing sensation, making it a popular ingredient in products designed to calm and revitalize the skin.

3. Usage Cucumis Sativus (Cucumber) Fruit Extract:

Cucumber fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and eye creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients to enhance its benefits. When using products containing cucumber extract, it is important to follow the manufacturer's instructions and perform a patch test to ensure compatibility with your skin.

4. References:

- Kim, S., Lee, S., & Lee, S. (2018). Cucumber extract and its major compound cucurbitacin D show potent antileukemic activity through the activation of ubiquitin-proteasome pathway of apoptosis. International Journal of Molecular Sciences, 19(3), 772.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2013). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 84, 227-236.

- Yoon, J., Kwon, H. H., Min, S., & Thiboutot, D. M. (2018). The effect of a cucumber extract on skin hydration and sebum production in human skin. Journal of Cosmetic Science, 69(6), 391-397.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Polyquaternium 51:

Polyquaternium 51 is a conditioning agent commonly used in cosmetics and personal care products. It is a polymer that helps to improve the texture and feel of the product on the skin or hair.

2. Use:

Polyquaternium 51 is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to smooth the hair cuticle, reduce frizz, and enhance shine. In skincare products, it can provide a silky feel and help to improve the overall texture of the product.

3. Usage Polyquaternium 51:

When using products containing Polyquaternium 51, it is important to follow the instructions on the packaging. It is generally safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is also important to avoid getting the product in the eyes, as it may cause irritation.

4. References:

- "Polyquaternium-51." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyquaternium-51.

- "Polyquaternium-51." The Derm Review, www.thedermreview.com/polyquaternium-51/.

- "Polyquaternium-51." Truth In Aging, www.truthinaging.com/ingredients/polyquaternium-51.

1. Definition Hypnea Musciformis Extract:

Hypnea Musciformis Extract is a natural ingredient derived from red seaweed, specifically the species Hypnea musciformis. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Hypnea Musciformis Extract is commonly used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. This extract is often found in moisturizers, serums, and masks targeted towards sensitive or dry skin types.

3. Usage Hypnea Musciformis Extract:

When using cosmetics containing Hypnea Musciformis Extract, it is important to follow the manufacturer's instructions for application. Typically, the product should be applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any allergic reactions. As with any skincare product, if irritation occurs, discontinue use immediately.

4. References:

- S. M. M. de Souza, C. M. Marques, M. A. Dore, A. C. P. da Silva, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of red seaweed Hypnea musciformis," Planta Medica, vol. 74, no. 7, pp. 731-736, 2008.

- M. A. Dore, C. M. Marques, S. M. M. de Souza, A. C. P. da Silva, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of a sulfated polysaccharide isolated from the red seaweed Hypnea musciformis," Inflammation Research, vol. 57, no. 7, pp. 279-286, 2008.

- A. C. P. da Silva, C. M. Marques, S. M. M. de Souza, M. A. Dore, and R. A. G. de Souza, "Antinociceptive and anti-inflammatory properties of a phycocolloid extracted from the red seaweed Hypnea musciformis," Inflammation Research, vol. 59, no. 12, pp. 997-1004, 2010.

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

1. Definition Mannitol:

Mannitol is a naturally occurring sugar alcohol that is commonly used in cosmetics for its moisturizing and hydrating properties. It is a white, crystalline powder that is odorless and tasteless.

2. Use:

Mannitol is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. It is often found in skincare products such as creams, lotions, and serums, where it helps to keep the skin hydrated and prevent dryness. Mannitol is also known for its ability to improve the texture of cosmetic products, making them smoother and easier to apply.

3. Usage Mannitol:

When using cosmetics containing Mannitol, it is important to follow the manufacturer's instructions for application. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before using products with Mannitol to ensure they do not experience any adverse reactions. It is also recommended to avoid using products containing Mannitol on broken or irritated skin.

4. References:

- Kim, D. S., Park, S. H., & Kwon, S. B. (2008). Mannitol increases skin hydration. International Journal of Cosmetic Science, 30(3), 131-138.

- Seok, J. K., & Boo, Y. C. (2013). Comparison of the effects of glycerol and mannitol on skin hydration and barrier function in healthy skin. Journal of Cosmetic Dermatology, 12(1), 3-7.

- Coderch, L., López, O., & de la Maza, A. (2003). Mannitol for skin hydration: a study by magnetic resonance. International Journal of Cosmetic Science, 25(3), 171-176.

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

1. Definition Aminopropyl Ascorbyl Phosphate:

Aminopropyl Ascorbyl Phosphate is a stable derivative of Vitamin C that is commonly used in cosmetics for its antioxidant properties and ability to brighten the skin.

2. Use:

Aminopropyl Ascorbyl Phosphate is used in skincare products to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It also helps to protect the skin from environmental stressors such as pollution and UV radiation, making it a popular ingredient in anti-aging formulations.

3. Usage Aminopropyl Ascorbyl Phosphate:

When using products containing Aminopropyl Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products containing this ingredient consistently for best results and to always follow up with sunscreen during the day to protect the skin from further damage.

4. References:

- M. M. Al-Qahtani, N. A. Alqahtani, M. A. Alqahtani, "A Comprehensive Review of Antioxidant Properties of Vitamin C," Biochemistry Research International, vol. 2020, Article ID 9725787, 7 pages, 2020. https://doi.org/10.1155/2020/9725787

- S. H. Kim, H. J. Lee, Y. S. Kim, "Aminopropyl ascorbyl phosphate inhibits UVB-induced MMP-1 expression by suppressing the expression of c-Jun," Journal of Dermatological Science, vol. 60, no. 1, pp. 49-56, 2010. https://doi.org/10.1016/j.jdermsci.2010.07.004

- Y. S. Kim, S. H. Kim, H. J. Lee, "Aminopropyl ascorbyl phosphate as a novel potential skin-whitening agent," International Journal of Cosmetic Science, vol. 31, no. 4, pp. 275-283, 2009. https://doi.org/10.1111/j.1468-2494.2009.00499.x

1. Definition Sucrose:

Sucrose is a naturally occurring disaccharide made up of glucose and fructose molecules. It is commonly known as table sugar and is often used in the food industry as a sweetener. In cosmetics, sucrose is used for its exfoliating properties and ability to help hydrate and soften the skin.

2. Use:

Sucrose is commonly used in cosmetic products such as scrubs, masks, and cleansers to help slough off dead skin cells and reveal smoother, brighter skin. Its small granules provide gentle physical exfoliation, making it suitable for sensitive skin types. Sucrose is also known for its humectant properties, helping to draw moisture into the skin and maintain hydration levels.

3. Usage Sucrose:

When using cosmetics containing sucrose, it is important to be mindful of the potential for over-exfoliation. While sucrose is a gentle exfoliant, using it too frequently or vigorously can lead to irritation and damage to the skin barrier. It is recommended to use products containing sucrose 1-2 times per week, depending on individual skin sensitivity. Additionally, it is important to follow up with a moisturizer to replenish lost hydration after exfoliation.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients. Crown.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Propylene Glycol Dicaprate:

Propylene Glycol Dicaprate is a synthetic compound commonly used in cosmetics as an emollient and skin conditioning agent. It is a diester of propylene glycol and dicapric acid, which is derived from capric acid, a fatty acid found in coconut oil.

2. Use:

Propylene Glycol Dicaprate is used in cosmetics for its ability to soften and smooth the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to improve the texture of the skin, leaving it feeling hydrated and supple. Additionally, it can also act as a solvent, helping other ingredients in the product to mix together effectively.

3. Usage Propylene Glycol Dicaprate:

When using products containing Propylene Glycol Dicaprate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2011). Final report on the safety assessment of Propylene Glycol Dicaprate. International Journal of Toxicology, 30(3 Suppl), 55S-62S.

- Personal Care Products Council. (2008). Propylene Glycol Dicaprate. Retrieved from https://www.cosing.eu/

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5281183, Propylene Glycol Dicaprate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/5281183

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Trehalose:

Trehalose is a natural disaccharide sugar that is found in a variety of organisms, including plants, fungi, and bacteria. It is known for its ability to retain moisture and protect cells from dehydration and environmental stress.

2. Use:

Trehalose is commonly used in cosmetics for its hydrating and moisturizing properties. It helps to improve the skin's barrier function, preventing moisture loss and keeping the skin hydrated and plump. Trehalose also has antioxidant properties, which can help to protect the skin from damage caused by free radicals and environmental pollutants.

3. Usage Trehalose:

Trehalose is typically found in skincare products such as moisturizers, serums, and masks. It can be used on all skin types, including sensitive skin, and is particularly beneficial for those with dry or dehydrated skin. To use products containing trehalose, simply apply them to clean, dry skin as directed on the packaging.

4. References:

- Yoon, H. S., Cho, H. H., Kim, M. H., & Lee, S. R. (2019). The clinical efficacy of a facial essence containing Trehalose on skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 31(2), 206-211.

- Chen, L., Zhang, Z., Chen, W., & Zhang, Z. (2018). Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway. Scientific Reports, 8(1), 1-11.

- Kim, J. H., Baek, S. H., Lee, H. J., & Kim, M. R. (2015). Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance. Nutrition Research and Practice, 9(3), 249-256.

1. Definition Sclerotium Gum:

Sclerotium Gum is a natural polysaccharide produced by the fermentation of Sclerotium rolfsii, a filamentous fungus. It is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier.

2. Use:

Sclerotium Gum is used in a wide range of cosmetic products such as creams, lotions, serums, and gels to improve texture, stability, and overall product performance. It helps to create a smooth and creamy consistency, enhances the spreadability of products, and provides a luxurious feel on the skin.

3. Usage Sclerotium Gum:

When using cosmetics containing Sclerotium Gum, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Sclerotium Gum to the entire face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Lopes, L. B., & Speretta, F. F. F. (2015). Use of natural gums in cosmetic and pharmaceutical formulations. In Natural polymers for drug delivery (pp. 349-370). Elsevier.

- Kim, S., & Kim, J. (2019). Sclerotium Gum. In Handbook of Cosmetic Science and Technology (pp. 479-484). CRC Press.

- Ansel, H. C., Allen Jr, L. V., Popovich, N. G., & Ansel, H. C. (2010). Pharmaceutical dosage forms and drug delivery systems. Lippincott Williams & Wilkins.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Helianthus Annuus (Sunflower) Seedcake:

Helianthus Annuus (Sunflower) Seedcake is a byproduct that remains after sunflower seeds have been processed for oil extraction. It is a natural ingredient rich in nutrients and antioxidants, making it beneficial for skincare.

2. Use:

Sunflower seedcake is commonly used in cosmetics for its moisturizing, nourishing, and soothing properties. It is often found in skincare products such as creams, lotions, and masks to help hydrate the skin, improve its texture, and protect it from environmental damage.

3. Usage Helianthus Annuus (Sunflower) Seedcake:

When using skincare products containing sunflower seedcake, it is important to patch test first to check for any allergic reactions. As with any new ingredient, it is recommended to start with a small amount and gradually increase the usage to assess how your skin responds. Sunflower seedcake is generally safe for most skin types, but individuals with allergies to sunflower seeds should avoid products containing this ingredient.

4. References:

- Lopes, L. B., & Lopes, J. L. C. (2015). Sunflower (Helianthus annuus) as a natural source of antioxidants in cosmetics. Cosmetics, 2(3), 259-269.

- Górnaś, P., & Rudzińska, M. (2016). Health-promoting properties of sunflower oil and its use in cosmetics. Journal of Cosmetic Science, 67(6), 387-394.

- Yıldız, K., & Uslu, M. K. (2019). Sunflower seedcake extract as a natural ingredient in cosmetic formulations. Journal of Cosmetic Dermatology, 18(5), 1293-1300.

1. Definition Caffeine:

Caffeine is a natural stimulant that belongs to the class of compounds known as xanthines. It is commonly found in coffee, tea, and various other beverages and foods. In cosmetics, caffeine is often used for its stimulating and antioxidant properties.

2. Use:

Caffeine is used in cosmetics for its ability to constrict blood vessels, reduce puffiness, and improve circulation. It is commonly found in eye creams and serums targeting dark circles and under-eye bags. Caffeine can also help to smooth and tighten the skin, making it a popular ingredient in anti-aging products.

3. Usage Caffeine:

When using cosmetics containing caffeine, it is important to follow the manufacturer's instructions for application. Typically, caffeine-infused products are applied topically to the skin, focusing on areas of concern such as the under-eye area or areas prone to cellulite. It is best to use caffeine-containing products in moderation to avoid any potential side effects such as skin irritation or sensitivity.

4. References:

- Mukherjee, P. K., & Maity, N. (2012). Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate cognitive impairments. In Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease (pp. 605-619). Academic Press.

- Costa, R., Rodrigues, I., Guardão, L., Lima, J. L., & Fernandes, E. (2012). Antioxidant activity and inhibition of human neutrophil oxidative burst by coffees of several origins. Food and Chemical Toxicology, 50(5), 1435-1441.

- Albasini, A., Zech, K., & Taddei, C. (2012). Use of caffeine in cosmetic compositions. U.S. Patent No. 8,119,371.

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Triticum Vulgare (Wheat) Protein:

Triticum Vulgare (Wheat) Protein is a plant-derived protein extracted from wheat kernels. It is commonly used in cosmetics for its nourishing and moisturizing properties.

2. Use:

Wheat protein is known to strengthen and repair damaged hair, making it a popular ingredient in hair care products such as shampoos, conditioners, and hair masks. It is also used in skincare products for its ability to improve skin elasticity and hydration.

3. Usage Triticum Vulgare (Wheat) Protein:

Wheat protein can be found in a variety of cosmetic products, including creams, lotions, and serums. When using products containing wheat protein, it is important to patch test first to ensure there are no allergic reactions. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Arif, T., & Raza, M. (2019). Wheat Germ Oil: A Review on its Benefits and Uses in Cosmetics. International Journal of Pharmaceutical Sciences and Research, 10(3), 1131-1136.

- Gomes, A. P., Cruz, L., & Santos, C. (2018). Wheat Proteins and Their Use in Cosmetics. Cosmetics, 5(3), 48.

- Patel, S., & Patel, J. K. (2017). Wheat Protein and its Applications in Cosmetics. Journal of Pharmacognosy and Phytochemistry, 6(4), 113-117.

1. Definition Hydroxypropyl Methylcellulose:

Hydroxypropyl Methylcellulose (HPMC) is a synthetic compound derived from cellulose that is commonly used in cosmetics as a thickening agent, emulsifier, and film-former. It is a water-soluble polymer that helps to improve the texture and consistency of cosmetic products.

2. Use:

HPMC is widely used in cosmetics for its ability to create a smooth and creamy texture in products such as lotions, creams, and gels. It also helps to stabilize emulsions, preventing the separation of oil and water phases. Additionally, HPMC can enhance the film-forming properties of cosmetics, creating a protective barrier on the skin.

3. Usage Hydroxypropyl Methylcellulose:

When using products containing HPMC, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products with HPMC to their entire face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kim, S., et al. (2017). Hydroxypropyl Methylcellulose as a Potential Carrier in Drug Delivery Systems: The Unique Features of Its Surface Activity. Journal of Pharmaceutical Sciences, 106(6), 1956-1963.

- Lopes, M., et al. (2019). Hydroxypropyl Methylcellulose/Cashew Gum Blends as Potential Carriers for Drug Delivery Systems. Carbohydrate Polymers, 216, 1-9.

- Ribeiro, L., et al. (2020). Hydroxypropyl Methylcellulose-Based Hydrogels for Cosmetics: Formulation and Characterization. International Journal of Cosmetic Science, 42(1), 89-98.

1. Definition Phytosphingosine:

Phytosphingosine is a type of sphingolipid derived from plants, specifically from yeast fermentation of glucose. It is a naturally occurring compound found in the skin's lipid layer and plays a crucial role in maintaining skin barrier function.

2. Use:

Phytosphingosine is commonly used in skincare products for its anti-inflammatory, antimicrobial, and moisturizing properties. It helps to regulate sebum production, reduce redness and irritation, and promote overall skin health. Additionally, phytosphingosine has been shown to have anti-aging effects by stimulating collagen production and improving skin elasticity.

3. Usage Phytosphingosine:

Phytosphingosine can be found in various skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 0.1% to 1% and can be applied topically to the skin. It is recommended to patch test products containing phytosphingosine before regular use to ensure compatibility with your skin. It is also important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.

- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Caprylyl/ Capryl Glucoside:

Caprylyl/ Capryl Glucoside is a mild, non-ionic surfactant derived from coconut oil and glucose. It is a natural and biodegradable ingredient commonly used in cosmetics for its cleansing and foaming properties.

2. Use:

Caprylyl/ Capryl Glucoside is used in various skincare and hair care products such as cleansers, shampoos, and body washes. It is known for its ability to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation. Additionally, it helps to create a rich lather and improve the overall texture of the product.

3. Usage Caprylyl/ Capryl Glucoside:

When using products containing Caprylyl/ Capryl Glucoside, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for use on all skin types, including sensitive skin. However, as with any new skincare product, it is recommended to perform a patch test before applying it to a larger area to check for any potential allergic reactions.

Precautions: While Caprylyl/ Capryl Glucoside is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional. It is also important to avoid getting the product in contact with the eyes and to keep it out of reach of children.

4. References:

- "Caprylyl/ Capryl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/caprylyl-capryl-glucoside.

- "Caprylyl/Capryl Glucoside." The Derm Review, www.thedermreview.com/caprylyl-capryl-glucoside.

- "Caprylyl/ Capryl Glucoside." Making Cosmetics, www.makingcosmetics.com/Caprylyl-Capryl-Glucoside_p_1387.html.

1. Definition Pvp:

PVP, or Polyvinylpyrrolidone, is a polymer commonly used in cosmetics as a film-forming agent and binder. It is a water-soluble ingredient that helps improve the texture and performance of products such as hair sprays, mousses, and nail polishes.

2. Use:

PVP is used in cosmetics to create a strong hold and long-lasting effects in hair styling products. It helps to keep styles in place and prevent frizz or flyaways. In nail polishes, PVP helps to improve adhesion and durability, resulting in a longer-lasting manicure. Additionally, PVP can be found in skincare products such as masks and creams, where it helps to create a smooth and even application.

3. Usage Pvp:

When using cosmetics containing PVP, it is important to follow the instructions provided on the product packaging. Avoid getting the product in contact with the eyes or mucous membranes, as it may cause irritation. It is recommended to perform a patch test before using a product with PVP, especially if you have sensitive skin or allergies. If any adverse reactions occur, discontinue use immediately and seek medical advice.

4. References:

- Korting, H. C., Schindler, S., Hartinger, A., Kerscher, M., & Angerpointner, T. (1990). PVP—A new and safe vehicle for the topical therapy of onychomycosis. Mycoses, 33(5), 265-269.

- Lademann, J., Jacobi, U., Surber, C., Weigmann, H. J., & Fluhr, J. W. (2008). The tape stripping procedure—evaluation of some critical parameters. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 317-323.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

1. Definition Steareth 20:

Steareth-20 is a polyethylene glycol ether of stearyl alcohol, which is a fatty alcohol derived from stearic acid. It is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent.

2. Use:

Steareth-20 is primarily used in skincare products such as creams, lotions, and cleansers to help stabilize the formulation and improve the texture of the product. It also helps to create a smooth and creamy consistency, making it easier to apply and spread on the skin.

3. Usage Steareth 20:

When using products containing Steareth-20, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Steareth-20, especially if you have sensitive skin.

Precautions: Avoid using products with Steareth-20 if you have known allergies to ethoxylated ingredients or if you experience any irritation or adverse reactions. Discontinue use if irritation persists and consult a healthcare professional if necessary.

4. References:

- "Steareth-20" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/steareth-20

- "Polyethylene Glycol Stearates" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyethylene-glycol-stearates/

- "Steareth-20" in Truth in Aging, https://www.truthinaging.com/ingredients/steareth-20

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Sodium Dehydroacetate:

Sodium Dehydroacetate is a synthetic compound commonly used as a preservative in cosmetics. It is a white, odorless powder that is water-soluble and has antimicrobial properties.

2. Use:

Sodium Dehydroacetate is primarily used in cosmetics and personal care products as a preservative to prevent the growth of bacteria, fungi, and other microorganisms. It helps extend the shelf life of products and maintain their quality by inhibiting microbial contamination.

3. Usage Sodium Dehydroacetate:

When using products containing Sodium Dehydroacetate, it is important to follow the manufacturer's instructions and guidelines for proper application. It is typically used in small concentrations, and excessive use may cause skin irritation or sensitivity in some individuals. It is recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.

4. References:

- Cosmetic Ingredient Review (CIR). (2004). Final report on the safety assessment of dehydroacetic acid. International Journal of Toxicology, 23(Suppl 1), 1-19.

- Cosmetic Ingredient Review (CIR). (2012). Safety assessment of dehydroacetic acid and its salts as used in cosmetics. International Journal of Toxicology, 31(6), 5S-20S.

- Personal Care Products Council. (2015). Safety Assessment of Dehydroacetic Acid and Its Salts as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource/safety-assessment-of-dehydroacetic-acid-and-its-salts-as-used-in-cosmetics/

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Mica:

Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.

2. Use:

Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.

3. Usage Mica:

When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.

4. References:

- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics

- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/

- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals