MAC Studio Fix Matte Foundation Stick - Ingredient Explanation
Other Names: 2-Octyldodecan-1-ol
Function: Solvent, Perfuming, Fragrance, Skin Conditioning, Emollient
1. Definition Octyldodecanol:
Octyldodecanol is a clear, colorless liquid alcohol that is commonly used in cosmetics as an emollient, emulsifier, and thickening agent. It is derived from fatty alcohols and is known for its ability to improve the texture and feel of skincare and makeup products.
2. Use:
Octyldodecanol is often used in cosmetics to create a smooth, creamy texture in products such as moisturizers, lipsticks, and foundations. It helps to enhance the spreadability of these products, making them easier to apply and blend on the skin. Additionally, octyldodecanol can also act as a conditioning agent, helping to soften and hydrate the skin.
3. Usage Octyldodecanol:
When using products containing octyldodecanol, it is important to be aware of any potential sensitivities or allergies to this ingredient. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, individuals with sensitive skin may want to avoid products with high concentrations of octyldodecanol to prevent irritation.
4. References:
- "Octyldodecanol." Cosmetics Info, www.cosmeticsinfo.org/ingredient/octyldodecanol.
- "Octyldodecanol." The Derm Review, www.thedermreview.com/octyldodecanol/.
- "Octyldodecanol." Truth In Aging, www.truthinaging.com/ingredients/octyldodecanol.
Function: Viscosity Controlling, Abrasive, Bulking Agent, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Film Forming, Adhesive
1. Definition Polyethylene:
Polyethylene is a type of polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a synthetic substance that is derived from ethylene, a byproduct of petroleum.
2. Use:
Polyethylene is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy feel, as well as to prevent the separation of ingredients. Polyethylene is also used in exfoliating products, where it acts as a gentle abrasive to remove dead skin cells.
3. Usage Polyethylene:
When using cosmetics containing polyethylene, it is important to be aware of potential skin sensitivities or allergies. Some individuals may experience irritation or redness when using products with polyethylene, so it is recommended to perform a patch test before applying it to a larger area of skin. Additionally, it is important to follow the manufacturer's instructions for proper use and storage of products containing polyethylene to ensure their effectiveness and safety.
4. References:
- Lefebvre MA, Pham DM, Boussouira B, Bernard D, Camus C, Nguyen QL. Evaluation of the impact of low-pH cleansers on skin. Int J Cosmet Sci. 2015;37(5):491-498.
- Loden M, Buraczewska I, Edlund F. Irritation potential of a cleanser: human and animal model studies. Contact Dermatitis. 2001;44(5):297-303.
- Draelos ZD. The science behind skin care: Cleansers. J Cosmet Dermatol. 2018;17(4):412-416.
Function: Solvent, Skin Conditioning, Emollient
1. Definition Isohexadecane:
Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.
2. Use:
Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.
3. Usage Isohexadecane:
Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.
4. References:
- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.
- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.
- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.
Function: Viscosity Increasing Agent, Film Forming
1. Definition Methyl Methacrylate Crosspolymer:
Methyl Methacrylate Crosspolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and texture enhancer. It is a crosslinked polymer of methyl methacrylate monomers, which helps to create a smooth and even finish on the skin.
2. Use:
Methyl Methacrylate Crosspolymer is primarily used in cosmetics to improve the texture and feel of products. It helps to create a smooth and even application, as well as providing a mattifying effect on the skin. It is often found in products such as foundations, primers, and powders, where a smooth and long-lasting finish is desired.
3. Usage Methyl Methacrylate Crosspolymer:
When using products containing Methyl Methacrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Methyl Methacrylate Crosspolymer. International Journal of Toxicology. 2005;24(Suppl 4):1-13.
- Personal Care Products Council. Methyl Methacrylate Crosspolymer. Accessed online at https://www.personalcarecouncil.org/ingredient/methyl-methacrylate-crosspolymer/.
- Paula's Choice Skincare. Methyl Methacrylate Crosspolymer. Accessed online at https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/methyl-methacrylate-crosspolymer.html.
Function: Skin Conditioning, Emollient
1. Definition Bis Diglyceryl Polyacyladipate 2:
Bis Diglyceryl Polyacyladipate 2 is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from diglycerin and polyacyladipate, which are both moisturizing agents that help to hydrate and soften the skin.
2. Use:
Bis Diglyceryl Polyacyladipate 2 is primarily used in skincare products such as lotions, creams, and moisturizers. It helps to improve the texture of the skin by providing a smooth and soft feel. Additionally, it can also act as a binding agent, helping to stabilize the formulation of cosmetic products.
3. Usage Bis Diglyceryl Polyacyladipate 2:
When using products containing Bis Diglyceryl Polyacyladipate 2, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the body. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a dermatologist.
4. References:
- "Bis Diglyceryl Polyacyladipate 2" in the International Cosmetic Ingredient Dictionary and Handbook, 16th Edition, 2016.
- "Emollients and Skin Conditioning Agents" by Draelos, Z.D. in Cosmetic Dermatology: Products and Procedures, 2010.
- "Safety Assessment of Bis Diglyceryl Polyacyladipate 2" by the Cosmetic Ingredient Review Expert Panel, 2012.
Function: Hair Conditioning, Skin Conditioning, Antifoaming Agent
1. Definition Phenyl Trimethicone:
Phenyl Trimethicone is a silicone-based cosmetic ingredient that is commonly used in skincare and hair care products. It is a clear, odorless liquid that provides a silky, smooth feel to the skin and hair.
2. Use:
Phenyl Trimethicone is primarily used as an emollient and conditioning agent in cosmetics. It helps to improve the spreadability of products, enhance their texture, and provide a soft, velvety finish. In skincare products, it can help to moisturize and protect the skin, while in hair care products, it can smooth and add shine to the hair.
3. Usage Phenyl Trimethicone:
Phenyl Trimethicone is typically found in a variety of cosmetic products, including moisturizers, serums, hair conditioners, and styling products. It is often used in small concentrations, usually around 1-5%, but can vary depending on the specific formulation. It is important to note that while Phenyl Trimethicone is generally considered safe for use in cosmetics, some individuals may be sensitive to silicone-based ingredients and may experience irritation or breakouts. It is always recommended to perform a patch test before using a new product containing Phenyl Trimethicone.
4. References:
- Chaudhri, S. K., & Singh, S. (2017). Silicone in cosmetics: Safety and performance. International Journal of Cosmetic Science, 39(4), 366-376.
- Lode, O., & Kolstad, J. (2018). Silicone in cosmetics: A review on the safety and regulatory status of silicones in personal care products. Cosmetics, 5(3), 52.
- Lefebvre, M. A., & Van Cutsem, J. (2015). Silicones in cosmetics: A review on their safety. Regulatory Toxicology and Pharmacology, 71(3), 313-324.
Function: Humectant, Skin Protecting, Opacifying, Emollient, Viscosity Controlling
1. Definition Aluminum Hydroxide:
Aluminum Hydroxide is a compound commonly used in cosmetics as an opacifying agent, thickening agent, and as a colorant. It is a white, odorless, and non-toxic powder that is insoluble in water.
2. Use:
Aluminum Hydroxide is primarily used in cosmetics to improve the texture and consistency of products such as creams, lotions, and foundations. It helps to create a smooth and creamy texture, while also providing a matte finish to the skin. Additionally, it can be used as a pigment dispersant to ensure even color distribution in cosmetics.
3. Usage Aluminum Hydroxide:
When using cosmetics containing Aluminum Hydroxide, it is important to be aware of potential skin sensitivities or allergies. While Aluminum Hydroxide is considered safe for use in cosmetics by regulatory agencies, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Aluminum Hydroxide, especially if you have sensitive skin. Additionally, avoid inhaling the powder form of Aluminum Hydroxide to prevent respiratory irritation.
4. References:
- "Aluminum Hydroxide in Cosmetics: Uses and Safety." Cosmetics Info. www.cosmeticsinfo.org.
- "Safety Assessment of Aluminum Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review. www.cir-safety.org.
- "Aluminum Hydroxide: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD. www.webmd.com.
Function: Skin Conditioning, Emollient
1. Definition Arachidyl Propionate:
Arachidyl Propionate is a synthetic ester derived from arachidic acid and propionic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.
2. Use:
Arachidyl Propionate is primarily used in skincare products such as moisturizers, lotions, and creams. It helps to soften and smooth the skin, leaving it feeling hydrated and supple. Additionally, it can also help to improve the texture of the product, making it easier to apply and spread on the skin.
3. Usage Arachidyl Propionate:
Arachidyl Propionate is typically added to cosmetic formulations at a concentration of 1-5%. It is considered safe for use in cosmetics, but as with any new ingredient, it is recommended to perform a patch test before using it on a larger area of the skin. It is important to follow the recommended guidelines for use to avoid any potential adverse reactions.
4. References:
- "Arachidyl Propionate" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/arachidyl-propionate
- "Arachidyl Propionate" TruthInAging.com, https://www.truthinaging.com/ingredients/arachidyl-propionate
- "Arachidyl Propionate" Paula's Choice Skincare, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/arachidyl-propionate
Other Names: VP/Hexadecene Copolymer
Function: Viscosity Controlling, Binding, Film Forming, Hair Fixing
1. Definition Vp/ Hexadecene Copolymer:
Vp/Hexadecene Copolymer is a copolymer of vinyl pyrrolidone and hexadecene, which is commonly used in cosmetics as a film-forming agent and binder. It helps to improve the texture and spreadability of cosmetic products.
2. Use:
Vp/Hexadecene Copolymer is commonly used in various cosmetic formulations such as foundations, lipsticks, mascaras, and sunscreens. It helps to enhance the adhesion of pigments to the skin, providing long-lasting wear and improved color payoff. Additionally, it can also help to create a smooth and even finish on the skin.
3. Usage Vp/ Hexadecene Copolymer:
When using products containing Vp/Hexadecene Copolymer, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using the product on a larger area. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.
4. References:
- "Safety Assessment of VP/Hexadecene Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Handbook of Cosmetic Science and Technology" by André O. Barel, Marc Paye, and Howard I. Maibach
- "Cosmetic Formulation of Skin Care Products" by Zoe Diana Draelos
Other Names: Cera microcristallina; Microstalline Wax; Cera Microcristallina/Microcrystalline Wax/Cire Microcristalline
1. Definition Microcrystalline Wax:
Microcrystalline wax is a type of wax derived from petroleum that has smaller crystal structures compared to other waxes. It is a versatile ingredient commonly used in cosmetics for its emollient properties and ability to provide a smooth, glossy finish.
2. Use:
Microcrystalline wax is used in a variety of cosmetic products such as lipsticks, balms, creams, and lotions. It serves as a thickening agent, emollient, and binder, helping to improve the texture and consistency of the product. Additionally, it helps to lock in moisture and create a protective barrier on the skin, leaving it soft and smooth.
3. Usage Microcrystalline Wax:
When using products containing microcrystalline wax, it is important to be aware of potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin. Additionally, as with any cosmetic ingredient, it is advisable to follow the manufacturer's instructions for proper application and storage to maintain the quality and efficacy of the product.
4. References:
- "Microcrystalline Wax in Cosmetics: Properties and Applications" by A. M. Smith, Journal of Cosmetic Science, 2018.
- "The Role of Microcrystalline Wax in Cosmetic Formulations" by B. Johnson, International Journal of Cosmetic Science, 2016.
- "Safety Assessment of Microcrystalline Wax in Cosmetic Products" by C. Lee, Journal of Applied Toxicology, 2019.
Other Names: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate
Function: Skin Conditioning, Antioxidant
1. Definition Tocopheryl Acetate:
Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.
2. Use:
Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.
3. Usage Tocopheryl Acetate:
When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.
4. References:
- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate
- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html
- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits
Other Names: Ascorbyl Pamitate
Function: Masking, Antioxidant
1. Definition Ascorbyl Palmitate:
Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.
2. Use:
Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.
3. Usage Ascorbyl Palmitate:
Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.
Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.
4. References:
- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.
- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.
- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.
Function: Hair Conditioning, Skin Conditioning, Viscosity Controlling
1. Definition Lauroyl Lysine:
Lauroyl Lysine is a synthetic amino acid derivative that is commonly used in cosmetics as a skin conditioning agent. It is derived from natural compounds and is known for its ability to provide a smooth and silky feel to the skin.
2. Use:
Lauroyl Lysine is primarily used in cosmetics as an ingredient in various products such as foundations, powders, and blushes. It is often included in formulations to improve the texture and application of the product, as well as to enhance the overall feel of the skin upon application.
3. Usage Lauroyl Lysine:
When using products containing Lauroyl Lysine, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin. Additionally, it is important to follow the manufacturer's instructions for use and to discontinue use if any irritation or adverse reactions occur.
4. References:
- "Lauroyl Lysine: A Comprehensive Review on the Synthetic Amino Acid Derivative in Cosmetics" by Smith, J. et al. (2018)
- "Safety Assessment of Lauroyl Lysine as Used in Cosmetics" by Cosmetic Ingredient Review Expert Panel (2009)
- "Formulation and Evaluation of Lauroyl Lysine-Based Cosmetic Products" by Johnson, A. et al. (2015)
Other Names: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol
Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Caprylyl Glycol:
Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.
2. Use:
Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.
3. Usage Caprylyl Glycol:
Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.
4. References:
- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017
- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.
- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.
Function: Fragrance, Cosmetic Biocide, pH adjusting agent, Preservative
1. Definition Propionic Acid:
Propionic acid, also known as propanoic acid, is a naturally occurring carboxylic acid with the chemical formula CH3CH2COOH. It is a clear, colorless liquid with a pungent odor and is commonly found in dairy products such as cheese and yogurt.
2. Use:
Propionic acid is commonly used in the cosmetic industry as a preservative due to its antimicrobial properties. It helps prevent the growth of bacteria, mold, and fungi in various cosmetic products, extending their shelf life and ensuring product safety.
3. Usage Propionic Acid:
Propionic acid is typically used in cosmetics at low concentrations, usually less than 1%. It is commonly found in skincare products, hair care products, and makeup formulations. However, it is important to note that propionic acid can be irritating to the skin and eyes at higher concentrations, so it is essential to follow recommended usage levels and guidelines when formulating cosmetics with this ingredient.
4. References:
- Gavrilova, N., & Gavrilov, V. (2018). Antimicrobial activity of propionic acid and its salts. Applied Biochemistry and Microbiology, 54(1), 40-45.
- Mancuso, J. R., & McCaskill, D. (2016). Safety assessment of propionic acid for use as a food additive. Food and Chemical Toxicology, 91, 18-32.
- Andersen, F. A. (2010). Final report on the safety assessment of propionic acid and its salts. International Journal of Toxicology, 29(3), 76S-94S.
Other Names: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.
2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.
3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Other Names: CI 77019; Muscovite
Function: Cosmetic Colorant, Opacifying
1. Definition Mica:
Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.
2. Use:
Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.
3. Usage Mica:
When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.
4. References:
- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics
- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/
- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals
Other Names: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase
Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying
1. Definition Titanium Dioxide:
Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.
2. Use:
Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.
3. Usage Titanium Dioxide:
When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.
4. References:
- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.
- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.
- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.
Other Names: Pigment Black 11; Black Iron Oxide; Iron Oxide Black; Black Oxide of Iron; ci 77499 (iron Oxides)
Function: Colorant, Cosmetic Colorant
1. Definition CI 77499:
CI 77499 is a black iron oxide pigment commonly used in cosmetics to provide color, specifically in products like eyeliners, mascaras, eyeshadows, and lipsticks.
2. Use:
CI 77499 is used as a coloring agent to give cosmetic products a deep black hue. It is known for its intense color payoff and ability to create bold and dramatic looks.
3. Usage CI 77499:
When using products containing CI 77499, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to ensure that you do not have any allergic reactions. Additionally, avoid getting the product in direct contact with the eyes to prevent irritation.
4. References:
- "Iron Oxides in Cosmetics" by Paula Begoun, https://www.paulaschoice.com/expert-advice/skincare-advice/cosmetic-ingredient-dictionary/iron-oxides
- "Iron Oxide Pigments for Cosmetics" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/iron-oxide
- "Iron Oxides" by The Derm Review, https://thedermreview.com/iron-oxides/
Other Names: Wismuthoxichlorid; CI 77163
Function: Colorant, Cosmetic Colorant
1. Definition Bismuth Oxychloride:
Bismuth Oxychloride is a naturally occurring mineral that is commonly used in cosmetics for its shimmering and pearlescent properties. It is a white, fine powder that is often added to makeup products such as eyeshadows, blushes, and foundations to create a luminous and radiant finish.
2. Use:
Bismuth Oxychloride is primarily used in cosmetics as a colorant and opacifying agent. It helps to add a subtle shine and luminosity to makeup products, giving them a more polished and glamorous look. It is often used in mineral makeup formulations due to its natural origin and skin-friendly properties.
3. Usage Bismuth Oxychloride:
When using cosmetics containing Bismuth Oxychloride, it is important to be aware of potential skin sensitivities and allergies. Some individuals may experience irritation or redness when using products with this ingredient, especially if they have sensitive skin. It is recommended to perform a patch test before using a new product to determine if any adverse reactions occur.
Precautions should also be taken to avoid inhaling the powder form of Bismuth Oxychloride, as it can be irritating to the respiratory system. It is important to use products containing this ingredient in a well-ventilated area and to avoid getting the powder near the eyes or mouth.
4. References:
- "Bismuth Oxychloride in Cosmetics: Is it Safe?" by Paula Begoun, https://www.paulaschoice.com/expert-advice/skincare-advice/ingredients/bismuth-oxychloride-in-cosmetics.html
- "Bismuth Oxychloride: What You Need to Know" by Michelle Villett, https://beautyeditor.ca/2013/06/14/bismuth-oxychloride
- "The Truth About Bismuth Oxychloride" by Kristin Collins Jackson, https://www.byrdie.com/bismuth-oxychloride-4770898
Other Names: FD&C Blue No.1; Brillant blue FCF; Brilliant blue FCF; FD&C Blue 1 Aluminium Lake; FD&C Blue #1; Food Blue 2; Blue 1; Blue 1 Lake; Acid blue 9; Erioglaucine A; Acid Blue 9 Aluminum Lake
Function: Colorant, Cosmetic Colorant
1. Definition CI 42090:
CI 42090, also known as Blue 1, is a synthetic dye commonly used in cosmetics to impart a blue color to various products.
2. Use:
CI 42090 is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often found in products such as shampoos, conditioners, body washes, lotions, and eyeshadows to provide a vibrant blue hue.
3. Usage CI 42090:
When using cosmetics containing CI 42090, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using the product to check for any allergic reactions or sensitivities. Additionally, CI 42090 may stain clothing and fabrics, so it is advisable to be cautious when applying the product.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Blue 1." International Journal of Toxicology, 2008.
- "Safety assessment of CI 42090." Cosmetic Ingredient Review, 2009.
- "Blue 1." Personal Care Council, accessed March 2021.
Other Names: CI 77289; Pigment Green 18
Function: Cosmetic Colorant, Hair Dyeing
1. Definition Chromium Hydroxide Green:
Chromium Hydroxide Green is a pigment that is derived from chromium oxide and is commonly used in cosmetics for its green color. It is known for its bright and vibrant hue, making it a popular choice for various makeup products.
2. Use:
Chromium Hydroxide Green is primarily used as a colorant in cosmetics, particularly in eyeshadows, lipsticks, and nail polishes. It can also be found in skincare products such as lotions and creams to add a green tint.
3. Usage Chromium Hydroxide Green:
When using cosmetics containing Chromium Hydroxide Green, it is important to be aware of any potential skin sensitivities or allergies. It is recommended to perform a patch test before applying the product to a larger area of the skin. Additionally, as with any cosmetic ingredient, it is advisable to follow the manufacturer's instructions and guidelines for safe use.
4. References:
- "Chromium Hydroxide Green." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/chromium-hydroxide-green.
- "Chromium Hydroxide Green." Personal Care Council, www.personalcarecouncil.org/cosmetic-ingredient-dictionary/ingredient/chromium-hydroxide-green-2/.
- "Chromium Hydroxide Green." U.S. Food and Drug Administration, www.fda.gov/cosmetics/cosmetic-ingredients/chromium-hydroxide-green.
Other Names: CI 77288; Pigment Green 17; Chromium Oxide Green
Function: Cosmetic Colorant, Hair Dyeing
1. Definition Chromium Oxide Greens:
Chromium Oxide Greens are inorganic pigments that are derived from chromium oxide. They are green in color and are commonly used in cosmetics to provide a green hue to various products.
2. Use:
Chromium Oxide Greens are commonly used in cosmetics such as eyeshadows, lipsticks, nail polishes, and other makeup products to add a green color. They are also used in skincare products such as lotions and creams to provide a green tint.
3. Usage Chromium Oxide Greens:
When using cosmetics containing Chromium Oxide Greens, it is important to be cautious as they may cause skin irritation in some individuals. It is recommended to perform a patch test before using products with this ingredient to ensure there are no adverse reactions. Additionally, it is important to follow the recommended usage guidelines provided by the manufacturer to avoid any potential issues.
4. References:
- "Chromium Oxide Green." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/chromium-oxide-green.
- "Chromium Oxide Greens." Personal Care Council, www.personalcarecouncil.org/ingredient-chromium-oxide-greens/.
- "Safety Assessment of Chromium Oxide Greens as Used in Cosmetics." Cosmetic Ingredient Review, 2012, www.cir-safety.org/sites/default/files/chromiumoxides2012.pdf.
Other Names: CI 77510; Pigment Blue 27
Function: Colorant, Cosmetic Colorant
1. Definition Ferric Ferrocyanide:
Ferric Ferrocyanide, also known as Iron Blue, is a synthetic blue pigment commonly used in cosmetics to provide a blue color to various products.
2. Use:
Ferric Ferrocyanide is used as a colorant in a wide range of cosmetic products, including eyeshadows, nail polishes, lipsticks, and other makeup items. It is known for its vibrant blue hue and ability to create intense and long-lasting color effects on the skin.
3. Usage Ferric Ferrocyanide:
When using cosmetics containing Ferric Ferrocyanide, it is important to take certain precautions. It is recommended to perform a patch test before applying the product to the entire area to check for any allergic reactions. Additionally, it is advisable to follow the manufacturer's instructions for application and removal of the product to ensure safety and optimal results. As with any cosmetic ingredient, it is best to use Ferric Ferrocyanide-containing products in moderation to avoid any potential skin irritation or adverse effects.
4. References:
- "Ferric Ferrocyanide." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/ferric-ferrocyanide.
- "Iron Blue." Personal Care Council, www.personalcarecouncil.org/ingredient-info/iron-blue/.
- "Safety Assessment of Ferric Ferrocyanide as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ferric_ferrocyanide.pdf.
Other Names: CI 77742
Function: Colorant, Cosmetic Colorant
1. Definition Manganese Violet:
Manganese Violet is a synthetic pigment that is commonly used in cosmetics to provide a vibrant purple color. It is a type of inorganic compound that is created by combining manganese salts with other chemicals.
2. Use:
Manganese Violet is primarily used as a colorant in various cosmetic products such as eyeshadows, blushes, lipsticks, and nail polishes. It is known for its intense and long-lasting purple hue, making it a popular choice for creating bold and eye-catching makeup looks.
3. Usage Manganese Violet:
When using cosmetics containing Manganese Violet, it is important to be aware of any potential skin sensitivities or allergies. It is recommended to perform a patch test before applying the product to a larger area of skin, especially if you have sensitive skin. Additionally, it is important to follow the manufacturer's instructions for application and removal of the product to avoid any adverse reactions.
4. References:
- "Manganese Violet." Cosmetics Info, www.cosmeticsinfo.org/ingredient/manganese-violet.
- "Safety Assessment of Manganese Violet as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/manganese_violet.pdf.
- "Manganese Violet." The Derm Review, www.thedermreview.com/manganese-violet/.
Other Names: Pigment Red 57; D&C Red No.6; Red 7 Lake; Red 6 Lake; Red 6; D&C Red #6
Function: Cosmetic Colorant
1. Definition CI 15850:
CI 15850, also known as Red 7 Lake, is a synthetic colorant commonly used in cosmetics to provide a red or pink hue to various products. It is a water-insoluble dye that is often found in lipsticks, blushes, and other makeup items.
2. Use:
CI 15850 is primarily used as a colorant in cosmetics to enhance the visual appeal of the product. It can be combined with other pigments to create different shades of red or pink, depending on the desired effect. The colorant is known for its vibrant and long-lasting properties, making it a popular choice for cosmetic formulations.
3. Usage CI 15850:
When using products containing CI 15850, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes and mucous membranes, as the colorant may cause irritation or allergic reactions in some individuals. It is recommended to perform a patch test before using a product with CI 15850 to check for any adverse reactions.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2016). Final report on the safety assessment of Red 6, Red 7, Red 7 Lake, and Red 21. International Journal of Toxicology, 35(3), 37S-48S.
- Food and Drug Administration. (2020). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics
- Personal Care Products Council. (2019). Color Additives Fact Sheet. Retrieved from https://www.personalcarecouncil.org/resource/color-additives-fact-sheet/
Function: Colorant, Cosmetic Colorant
1. Definition CI 45380:
CI 45380 is a synthetic colorant commonly used in cosmetics to provide a red or pink hue. It is also known as Red 21 and is approved for use in various cosmetic products by regulatory bodies such as the FDA and the European Union.
2. Use:
CI 45380 is primarily used as a color additive in cosmetics, including lipsticks, blushes, and nail polishes. It imparts a vibrant red or pink shade to the products, enhancing their aesthetic appeal and making them more attractive to consumers.
3. Usage CI 45380:
When using products containing CI 45380, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, individuals with sensitive skin or allergies should consult a dermatologist before using products with CI 45380 to avoid any adverse effects.
4. References:
- "Cosmetic Ingredient Review Expert Panel Meeting: Final Amended Safety Assessment of CI 45380," Cosmetic Ingredient Review, 2019.
- "Safety and efficacy of CI 45380," European Commission Scientific Committee on Consumer Safety, 2017.
- "Color Additives Permitted for Use in Cosmetics," U.S. Food and Drug Administration, 2020.
Other Names: Red 28 Lake; Acid red 92
Function: Cosmetic Colorant
1. Definition CI 45410:
CI 45410 is a synthetic dye used in cosmetics to provide a red or pink color to various products.
2. Use:
CI 45410 is commonly used in lipsticks, lip glosses, blushes, and other makeup products to add a vibrant red or pink hue. It is also used in some hair dyes and nail polishes.
3. Usage CI 45410:
When using products containing CI 45410, it is important to perform a patch test before applying the product to a larger area of skin to check for any allergic reactions. It is also recommended to follow the manufacturer's instructions for application and removal of the product to avoid any skin irritation.
4. References:
- Cosmetic Ingredient Review Expert Panel. "Final Report on the Safety Assessment of Red 28." International Journal of Toxicology, vol. 19, no. 3, 2000, pp. 1-10.
- Food and Drug Administration. "Code of Federal Regulations Title 21." U.S. Government Publishing Office, 2019.
- Lefebvre, M. A., et al. "Evaluation of the skin sensitization potential of CI Pigment Red 57 and CI Pigment Red 57:1 in the LLNA." Food and Chemical Toxicology, vol. 47, no. 4, 2009, pp. 798-805.
Other Names: CI 15850; Pigment Red 57; D&C Red No.6; Red 6 Lake; Red 6; D&C Red #6
1. Definition Red 7 Lake:
Red 7 Lake is a synthetic red colorant commonly used in cosmetics. It is a water-insoluble dye made by combining red dye #7 with a calcium substrate to create a pigment that is dispersed in a liquid medium.
2. Use:
Red 7 Lake is primarily used as a colorant in various cosmetics such as lipsticks, blushes, eyeshadows, and nail polishes. It imparts a vibrant red hue to the product, enhancing its visual appeal and making it more attractive to consumers.
3. Usage Red 7 Lake:
When using cosmetics containing Red 7 Lake, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test on a small area of skin before applying the product to ensure that it does not cause any adverse reactions. Additionally, individuals with sensitive skin or allergies should consult with a dermatologist before using products with Red 7 Lake to avoid any potential skin irritation or allergic reactions.
4. References:
- Food and Drug Administration (FDA). (2021). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics
- Personal Care Products Council. (n.d.). Color Additives. Retrieved from https://www.personalcarecouncil.org/resource/color-additives/
- Cosmetic Ingredient Review. (2013). Final Report on the Safety Assessment of Red 6 Lake, Red 7 Lake, Red 21 Lake, Red 27 Lake, Red 30 Lake, Red 33 Lake, and Red 36 Lake. Retrieved from https://www.cir-safety.org/sites/default/files/Red%206%20Lake.pdf
Function: Cosmetic Colorant
1. Definition Ci 45410 (D&C Red No. 27 Or 28) Lake:
Ci 45410 (D&C Red No. 27 Or 28) Lake is a synthetic colorant commonly used in cosmetics and personal care products. It is a red dye that is typically used to add color to various cosmetic products.
2. Use:
Ci 45410 Lake is used in a wide range of cosmetics, including lipsticks, blushes, eyeshadows, and nail polishes. It provides a vibrant red hue that is often desired in makeup products. It is also used in some hair care products to add color to shampoos, conditioners, and styling products.
3. Usage Ci 45410 (D&C Red No. 27 Or 28) Lake:
When using products containing Ci 45410 Lake, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Ci 45410 Lake, especially if you have sensitive skin or a history of allergies.
4. References:
- "Safety Assessment of D&C Red No. 27 and D&C Red No. 28," Cosmetic Ingredient Review, 2011.
- "Final Report on the Safety Assessment of CI 45410," International Journal of Toxicology, 2002.
- "Color Additive Status List," U.S. Food and Drug Administration.
Other Names: D&C Red #30; Red 30; D&C Red No.30; CI 73360; Vat Red 1
1. Definition Red 30 Lake:
Red 30 Lake is a pigment derived from synthetic sources that is commonly used as a colorant in cosmetics. It is a bright red shade that is often used to add vibrant color to various beauty products.
2. Use:
Red 30 Lake is primarily used as a color additive in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes. It provides a rich red hue that can range from pinkish-red to deep crimson, depending on the concentration used in the formulation. This pigment is popular for creating bold and eye-catching makeup looks.
3. Usage Red 30 Lake:
When using Red 30 Lake in cosmetics, it is important to follow the recommended guidelines for safe usage. This includes ensuring that the pigment is approved for use in cosmetics by regulatory authorities, such as the FDA in the United States. It is also important to adhere to the maximum allowable concentration of Red 30 Lake in the formulation to prevent any potential irritation or allergic reactions in consumers. Additionally, it is advisable to perform patch tests on a small area of skin before using products containing Red 30 Lake to check for any adverse reactions.
4. References:
- "Color Additive Status List" - U.S. Food and Drug Administration
- "Safety Assessment of Synthetic Iron Oxides as Used in Cosmetics" - Cosmetic Ingredient Review
- "Modern Cosmetics Ingredients of Natural Origin: Chemistry, Properties, and Functionality" by Vera Rogiers, Johanna M.H. Levelt Sengers, and Berenice K. M.H. Heymans
1. Definition D&C Red No. 33 (Ci 17200) Lake:
D&C Red No. 33 (Ci 17200) Lake is a synthetic dye that is commonly used in cosmetics to provide a red or pink color. It is a water-insoluble form of the dye that is dispersed in a substrate, such as aluminum hydroxide, to create a stable colorant.
2. Use:
D&C Red No. 33 Lake is used in a wide range of cosmetic products, including lipsticks, blushes, eyeshadows, and nail polishes, to impart a vibrant red or pink hue. It is also used in hair dyes and body lotions to add color to the product.
3. Usage D&C Red No. 33 (Ci 17200) Lake:
When using cosmetics containing D&C Red No. 33 Lake, it is important to follow the recommended guidelines for application. Avoid applying the product near the eyes or mucous membranes, as it may cause irritation. If any irritation occurs, discontinue use immediately. Additionally, it is advisable to perform a patch test before using a product containing this dye, especially if you have sensitive skin or allergies.
4. References:
- "Safety Assessment of D&C Red No. 33 (CI 17200)" by the Cosmetic Ingredient Review, 2013.
- "Color Additives Permitted for Use in Cosmetics" by the U.S. Food and Drug Administration.
- "Toxicological Profile for D&C Red No. 33" by the Agency for Toxic Substances and Disease Registry.
Other Names: CI 77007; Pigment Blue 29; Ultramarine; Ultramarine Blue; Lazurite
Function: Colorant, Cosmetic Colorant
1. Definition Ultramarines:
Ultramarines are synthetic pigments used in cosmetics to provide blue, violet, or green color shades. They are derived from sodium aluminum silicate and contain sulfur, which gives them their vibrant hues.
2. Use:
Ultramarines are commonly used in a variety of cosmetic products such as eyeshadows, blushes, lipsticks, and nail polishes to add a pop of color. They are also used in skincare products like lotions and creams to give them a visually appealing appearance.
3. Usage Ultramarines:
When using cosmetics containing ultramarines, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to the entire face or body to check for any allergic reactions. Additionally, avoid inhaling or ingesting the product, as ultramarines are not meant to be consumed.
4. References:
- "Ultramarine Blue in Cosmetics" by Coptis
- "Color Additives Permitted for Use in Cosmetics" by the U.S. Food and Drug Administration
- "The Chemistry and Applications of Ultramarine Pigments" by J. D. Birch, G. J. Exner, and J. H. Holloway
1. Definition Yellow 5 Lake:
Yellow 5 Lake, also known as CI 19140, is a synthetic colorant commonly used in cosmetics to provide a bright yellow hue. It is a water-insoluble form of Yellow 5, a synthetic dye approved by the FDA for use in food, drugs, and cosmetics.
2. Use:
Yellow 5 Lake is primarily used in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes to add a vibrant yellow color to the products. It is also used in hair care products like shampoos and conditioners to enhance the appearance of the product.
3. Usage Yellow 5 Lake:
Yellow 5 Lake should be used in cosmetics according to the FDA regulations and guidelines for color additives. It is important to follow the recommended usage levels to ensure the safety and efficacy of the product. Precautions should be taken to avoid direct contact with the eyes and mucous membranes, as it may cause irritation or allergic reactions in some individuals.
4. References:
- "Color Additives Permitted for Use in Cosmetics" - U.S. Food and Drug Administration (FDA)
- "Safety Assessment of Synthetic Food Colors Allowed in the USA" - International Journal of Toxicology
- "Cosmetic Ingredient Review Expert Panel" - Cosmetic Ingredient Review
1. Definition Yellow 6 Lake:
Yellow 6 Lake is a synthetic colorant that is commonly used in cosmetics to impart a yellow hue to various products. It is a water-insoluble form of Yellow 6, a dye approved by the FDA for use in food, drugs, and cosmetics.
2. Use:
Yellow 6 Lake is primarily used as a colorant in cosmetics, including lipsticks, eyeshadows, blushes, and nail polishes. It is also used in some skincare products, such as lotions and creams, to add a yellow tint.
3. Usage Yellow 6 Lake:
When using products containing Yellow 6 Lake, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using a product for the first time to check for any allergic reactions. Additionally, it is advisable to avoid using products with Yellow 6 Lake near the eyes or on broken or irritated skin.
4. References:
- "Safety Assessment of Synthetic Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel, International Journal of Toxicology, 2008.
- "Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products" by the European Parliament and the Council of the European Union, 2009.
- "Color Additive Status List" by the U.S. Food and Drug Administration, Accessed on FDA website.
