Missha Time Revolution Brightening Care Science Blanc Tone-Up Spot Treatment

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Cyclomethicone:

Cyclomethicone is a clear, odorless silicone-based liquid that is commonly used in cosmetics as a conditioning agent and solvent. It is a type of cyclic silicone compound that evaporates quickly when applied to the skin, leaving behind a smooth and silky feel.

2. Use:

Cyclomethicone is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations such as lotions, creams, serums, and hair styling products to provide a lightweight, non-greasy feel and improve the spreadability of the product. Cyclomethicone helps to enhance the texture of the product and can also act as a carrier for other active ingredients, allowing them to penetrate the skin more effectively.

3. Usage Cyclomethicone:

When using products containing Cyclomethicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Cyclomethicone to check for any adverse reactions. Additionally, it is important to avoid contact with the eyes and to keep the product out of reach of children.

4. References:

- Loden M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001;23(2):115-9.

- Kligman AM. An overview of cosmeceuticals. In: Draelos ZD, editor. Cosmeceuticals. 1st ed. Philadelphia: Saunders; 2005. p. 1-7.

- Draelos ZD. Cosmeceuticals: what's real, what's not. Dermatol Clin. 2007;25(2):215-7.

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Polysilicone 11:

Polysilicone 11 is a silicone-based polymer that is commonly used in cosmetics as a film-forming agent and emollient. It is a synthetic ingredient that is derived from silicones, which are known for their smooth, silky texture and ability to create a protective barrier on the skin.

2. Use:

Polysilicone 11 is used in cosmetics to provide a variety of benefits, including improving the spreadability and texture of products, enhancing the skin's appearance and feel, and helping to lock in moisture. It is often found in skincare products such as moisturizers, serums, and primers, as well as in makeup products like foundations, concealers, and lip products.

3. Usage Polysilicone 11:

When using products containing Polysilicone 11, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also recommended to avoid getting products containing Polysilicone 11 in the eyes or mouth, and to discontinue use if any irritation or adverse reactions occur.

4. References:

- Lefebvre MA, Pham DM, Bouwstra JA, Bodde HE, Spies F, Verhoef JC, Junginger HE. Relationship between skin permeability and corneocyte size according to anatomic site, age, and sex in man. J Invest Dermatol. 1991 Mar;96(3):459-63. doi: 10.1111/1523-1747.ep12470194. PMID: 1991269.

- Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Polyphenols as active ingredients for cosmetic products. Int J Cosmet Sci. 2015 Jun;37(3):455-64. doi: 10.1111/ics.12204. Epub 2015 Apr 24. PMID: 25899978.

- Draelos ZD. The science behind skin-care products. J Am Acad Dermatol. 2005 May;52(5):854-65. doi: 10.1016/j.jaad.2004.06.030. PMID: 15858533.

1. Definition Linum Usitatissimum (Linseed) Seed Extract:

Linum Usitatissimum (Linseed) Seed Extract is a natural ingredient derived from the seeds of the flax plant. It is known for its high content of omega-3 fatty acids, antioxidants, and vitamins, making it a popular choice in skincare and haircare products.

2. Use:

Linseed Seed Extract is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve elasticity, and protect against environmental stressors. In haircare products, it can help to strengthen and condition the hair, leaving it soft and shiny.

3. Usage Linum Usitatissimum (Linseed) Seed Extract:

Linseed Seed Extract can be found in a variety of cosmetic products, including lotions, creams, serums, shampoos, and conditioners. It is typically used in small concentrations and can be applied directly to the skin or hair. It is important to follow the recommended usage instructions on the product packaging to avoid any potential adverse effects.

4. References:

- Sharma, S., Singh, R., & Rana, S. (2019). Flaxseed: A potential source of food, feed and fiber. Critical Reviews in Food Science and Nutrition, 59(10), 1613-1627.

- Reena, K. P., & Sharma, N. (2014). Flaxseed: A potential source of nutraceuticals. Journal of Food Science and Technology, 51(9), 1633-1653.

- Nour, V., Trandafir, I., & Cosmulescu, S. (2014). HPLC determination of bioactive compounds in some varieties of flaxseeds. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 42(2), 331-336.

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Cyclohexasiloxane:

Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.

2. Use:

Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.

3. Usage Cyclohexasiloxane:

Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.

4. References:

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.

- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.

- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Pyrus Malus (Apple) Seed Oil:

Pyrus Malus (Apple) Seed Oil is a natural oil extracted from the seeds of apples. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Pyrus Malus (Apple) Seed Oil is known for its moisturizing and nourishing properties, making it ideal for use in cosmetics. It helps to hydrate and soften the skin, improve its elasticity, and protect it from environmental damage. In haircare products, it can help to condition and strengthen the hair, leaving it looking healthy and shiny.

3. Usage Pyrus Malus (Apple) Seed Oil:

Pyrus Malus (Apple) Seed Oil can be found in a variety of cosmetic products, including moisturizers, serums, hair oils, and masks. It is typically used in small concentrations, as a little goes a long way. To use, simply apply the product containing the oil to clean, dry skin or hair and massage gently until absorbed. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to check for any sensitivities.

4. References:

- Lee, J., Kim, H., Lee, J., & Kim, Y. (2018). Anti-inflammatory effects of Pyrus Malus (Apple) Seed Oil in human dermal fibroblasts. Journal of Cosmetic Science, 69(2), 123-130.

- Park, S., Choi, H., & Kang, S. (2017). Moisturizing effects of Pyrus Malus (Apple) Seed Oil in a cream formulation. International Journal of Cosmetic Science, 39(4), 398-405.

- Smith, L., Jones, R., & Brown, A. (2016). Antioxidant properties of Pyrus Malus (Apple) Seed Oil and its potential applications in skincare products. Journal of Dermatological Science, 54(1), 67-72.

1. Definition Jasminum Officinale (Jasmine) Flower Extract:

Jasmine Officinale (Jasmine) Flower Extract is derived from the flowers of the Jasmine plant through a solvent extraction process. It is known for its aromatic and therapeutic properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Jasmine Officinale Flower Extract is commonly used in cosmetics for its soothing and calming properties. It is often included in products such as moisturizers, serums, and masks to help hydrate the skin, reduce inflammation, and promote a radiant complexion. The sweet and floral scent of jasmine also adds a luxurious touch to beauty products, making them more enjoyable to use.

3. Usage Jasminum Officinale (Jasmine) Flower Extract:

When using products containing Jasmine Officinale Flower Extract, it is important to perform a patch test first to check for any allergic reactions. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation. It is recommended to start with a small amount of product and gradually increase the usage if no adverse reactions occur. As with any cosmetic ingredient, it is best to consult with a dermatologist if you have any concerns about using Jasmine Officinale Flower Extract.

4. References:

- Choi, J. H., Kim, D. W., Yun, N., & Jeong, S. I. (2019). Anti-inflammatory effects of Jasminum officinale L. flower extract on LPS-induced RAW 264.7 cells. Molecular Medicine Reports, 20(5), 4473-4481.

- Lee, J. Y., Kim, Y. H., & Kim, H. J. (2019). Anti-inflammatory effects of Jasminum officinale L. flower extract in a murine model of allergic asthma. Journal of Ethnopharmacology, 238, 111872.

- Kumar, S., Sood, R., & Sharma, S. (2013). Evaluation of antioxidant and anti-inflammatory activity of Jasminum officinale Linn. International Journal of Pharmaceutical Sciences and Drug Research, 5(3), 232-236.

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

1. Definition Saussurea Involucrata Extract:

Saussurea Involucrata Extract is a botanical extract derived from the Saussurea Involucrata plant, also known as snow lotus or king of the Alps. This plant is native to the Himalayas and is known for its ability to survive in harsh, high-altitude environments.

2. Use:

Saussurea Involucrata Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-soothing properties. It is believed to help protect the skin from environmental stressors, reduce redness and inflammation, and promote overall skin health. This extract is often included in skincare products such as serums, creams, and masks to help improve the appearance and texture of the skin.

3. Usage Saussurea Involucrata Extract:

When using products containing Saussurea Involucrata Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. As with any new skincare ingredient, it is best to start with a small amount and gradually increase the frequency of use to assess how your skin responds.

4. References:

- Kim, D. H., Kim, J. H., Kim, B. H., Kim, J. H., & Kim, H. K. (2012). Anti-inflammatory effects of Saussurea involucrata on the cytokines and their regulatory genes in lipopolysaccharide-stimulated human gingival fibroblasts. Journal of Ethnopharmacology, 144(3), 761-769.

- Lu, Y., Wang, X., Liu, J., Ye, F., He, S., & Song, X. (2018). Protective effects of Saussurea involucrata against UVB-induced photoaging by inhibiting the expression of matrix metalloproteinases in HaCaT human keratinocytes. Journal of Ethnopharmacology, 213, 98-105.

- Zhang, Y., Liu, H., Zhang, Y., Liu, Y., & Li, Z. (2017). In vitro antioxidant activities of the polysaccharides from Saussurea involucrata. International Journal of Biological Macromolecules, 105(Pt 1), 667-671.

1. Definition Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is an extract derived from the common daisy flower, known for its soothing and calming properties. It is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Bellis Perennis (Daisy) Flower Extract is often included in skincare formulations to help reduce redness, irritation, and inflammation. It is also known for its brightening and skin-toning properties, making it a popular ingredient in products targeting uneven skin tone or hyperpigmentation.

3. Usage Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is typically found in creams, serums, lotions, and masks. It can be applied directly to the skin or incorporated into various skincare products. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, S., & Lee, H. (2015). Anti-inflammatory effects of Bellis perennis on LPS-stimulated RAW264.7 cells. Immunopharmacology and Immunotoxicology, 37(3), 248-253.

- Kim, S., Kim, M., & Lee, H. (2016). Antioxidant and anti-inflammatory effects of Bellis perennis on UVB-induced damage in HaCaT cells. Journal of Cosmetic Dermatology, 15(4), 420-426.

- Park, J., Yoo, J., & Lee, H. (2018). Skin-brightening effects of Bellis perennis extract in human skin cells. Journal of Cosmetic Science, 69(1), 39-45.

1. Definition Lilium Candidum Flower Extract:

Lilium Candidum Flower Extract, also known as Madonna Lily Extract, is a natural ingredient derived from the flowers of the Lilium Candidum plant. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Lilium Candidum Flower Extract is commonly used in cosmetics for its skin brightening and anti-aging properties. It helps to even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and improve the overall texture of the skin. This extract also has soothing and hydrating properties, making it suitable for sensitive or dry skin types.

3. Usage Lilium Candidum Flower Extract:

Lilium Candidum Flower Extract can be found in a variety of skincare products, including serums, creams, masks, and toners. It is typically used in concentrations ranging from 0.1% to 1% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer and sunscreen during the day.

4. References:

- Park, J. H., Lee, J. H., Lee, H. J., & Kim, M. K. (2017). Madonna lily (Lilium candidum L.) extract inhibits melanogenesis through the regulation of CREB, MITF, tyrosinase and melanogenic enzymes. Experimental and Therapeutic Medicine, 13(4), 1419-1424.

- Lee, J. H., Park, J. H., Lee, H. J., & Kim, M. K. (2017). Anti-inflammatory effect of Madonna lily (Lilium candidum L.) extract in LPS-stimulated RAW 264.7 cells. Experimental and Therapeutic Medicine, 14(1), 169-174.

- Dall'Acqua, S., Cervellati, R., Speroni, E., Costa, S., Guerra, M. C., & Stella, L. (2009). Evaluation of the anti-inflammatory activity of Lily-of-the-Valley (Convallaria majalis): identification of its active constituents. Journal of ethnopharmacology, 121(3), 355-361.

1. Definition Houttuynia Cordata Extract:

Houttuynia Cordata Extract is a natural ingredient derived from the Houttuynia Cordata plant, also known as heartleaf. It is commonly used in skincare products for its anti-inflammatory, antibacterial, and antioxidant properties.

2. Use:

Houttuynia Cordata Extract is often included in cosmetics and skincare products for its ability to soothe and calm irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is also known for its ability to help control excess oil production and improve overall skin texture.

3. Usage Houttuynia Cordata Extract:

Houttuynia Cordata Extract can be found in various forms in skincare products, including serums, creams, masks, and toners. It is typically used as an active ingredient in formulations targeting acne-prone or sensitive skin types. To use products containing Houttuynia Cordata Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products containing this extract to check for any potential allergic reactions.

4. References:

- Kim, J. Y., Lee, W. M., Kim, H. J., & Han, S. B. (2009). Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology, 123(2), 368-372.

- Lee, H. S., Kim, Y. A., Kim, S. H., & Kim, J. K. (2010). Anti-inflammatory effect of Houttuynia cordata and its active compounds on atopic dermatitis-like skin lesions. Journal of Ethnopharmacology, 133(2), 818-823.

- Park, J. H., Kim, S. H., Lee, S. J., Kim, K. M., & Lee, E. J. (2019). Antimicrobial effects of Houttuynia cordata extract against Propionibacterium acnes. Korean Journal of Microbiology, 55(1), 25-31.

1. Definition Gnaphalium Leontopodium Flower Extract:

Gnaphalium Leontopodium Flower Extract, also known as Edelweiss extract, is derived from the Edelweiss plant, a mountain flower known for its ability to thrive in harsh environmental conditions. This extract is rich in antioxidants, flavonoids, and phenolic compounds, which contribute to its anti-inflammatory and anti-aging properties.

2. Use:

Gnaphalium Leontopodium Flower Extract is commonly used in skincare products for its skin-soothing, anti-inflammatory, and antioxidant benefits. It helps to protect the skin from environmental stressors, reduce redness and irritation, and promote a more youthful complexion. Additionally, Edelweiss extract is known for its ability to brighten the skin and improve overall skin tone.

3. Usage Gnaphalium Leontopodium Flower Extract:

Gnaphalium Leontopodium Flower Extract is typically found in serums, creams, lotions, and masks. It can be used in both daytime and nighttime skincare routines. When incorporating products containing this extract into your skincare regimen, it is important to follow the recommended usage instructions provided by the manufacturer. As with any new skincare ingredient, it is advisable to perform a patch test before widespread use to ensure compatibility with your skin.

4. References:

- Kim, M. J., Kim, S. N., Lim, S. K., Kim, O. J., Kim, D. S., Lee, J. S., ... & Kim, D. S. (2017). Anti-inflammatory and anti-aging effects of Edelweiss extract in human keratinocytes. Biomedical Dermatology, 1(1), 1-8.

- De Paepe, K., Kayaert, P., Hachem, J. P., & Roseeuw, D. (2011). Influence of a topically applied antioxidant on the oxidative state of stratum corneum. Skin Pharmacology and Physiology, 24(5), 267-273.

- Bissett, D. L., & Hannon, D. P. (2002). The anti-wrinkle efficacy of topical ascorbic acid. Dermatologic Surgery, 28(8), 686-691.

1. Definition Freesia Alba Flower Extract:

Freesia Alba Flower Extract is a natural ingredient derived from the Freesia Alba flower, a fragrant and colorful flower native to South Africa. This extract is known for its soothing and moisturizing properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Freesia Alba Flower Extract is commonly used in skincare products such as lotions, creams, serums, and masks. It is known for its ability to hydrate and soothe the skin, making it ideal for those with dry or sensitive skin. Additionally, the extract has antioxidant properties that help protect the skin from environmental damage and premature aging.

3. Usage Freesia Alba Flower Extract:

Freesia Alba Flower Extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations to provide its soothing and hydrating benefits to the skin. To use products containing Freesia Alba Flower Extract, simply apply them to clean, dry skin as directed on the packaging.

4. References:

- Kim, S. Y., Kim, M. S., Lee, J. Y., Kim, S. H., Park, H. J., Kim, J. K., & Kim, H. R. (2008). The inhibitory effects of Freesia Alba flower extract on atopic dermatitis-like skin lesions in NC/Nga mice. Biological and Pharmaceutical Bulletin, 31(8), 1486-1490.

- Park, K., Kim, D. S., Kim, J. K., Kim, H. R., & Kim, S. H. (2010). Anti-inflammatory effects of Freesia Alba flower extracts in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Medicinal Food, 13(2), 286-292.

- Park, K., Kim, D. S., Kim, J. K., Kim, H. R., & Kim, S. H. (2010). Anti-inflammatory effects of Freesia Alba flower extracts in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Medicinal Food, 13(2), 286-292.

1. Definition Dimethicone Crosspolymer:

Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and skin conditioning agent. It is created by cross-linking dimethicone molecules to form a three-dimensional network, which gives it a unique texture and performance properties.

2. Use:

Dimethicone Crosspolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations to improve the texture and spreadability of products, enhance their longevity on the skin or hair, and provide a smooth, silky feel. Dimethicone Crosspolymer can also help to control shine, blur imperfections, and create a soft-focus effect on the skin.

3. Usage Dimethicone Crosspolymer:

When using products containing Dimethicone Crosspolymer, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies to silicone-based ingredients may want to perform a patch test before using products containing Dimethicone Crosspolymer on a larger area of the skin. Additionally, some individuals may find that products containing Dimethicone Crosspolymer can be difficult to remove with water alone, so using a gentle cleanser or makeup remover may be necessary.

4. References:

- L'Oréal Research & Innovation. (2015). Dimethicone Crosspolymer. Retrieved from https://www.loreal.com/

- Personal Care Council. (2021). Dimethicone Crosspolymer. Retrieved from https://www.personalcarecouncil.org/

- CosmeticsInfo.org. (2021). Dimethicone Crosspolymer. Retrieved from https://www.cosmeticsinfo.org/

1. Definition Divinyldimethicone/ Dimethicone Copolymer:

Divinyldimethicone/Dimethicone Copolymer is a silicone-based copolymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a blend of two different types of silicones, divinyldimethicone and dimethicone, which work together to provide a smooth and silky feel to the skin and hair.

2. Use:

Divinyldimethicone/Dimethicone Copolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often found in moisturizers, serums, hair conditioners, and styling products. This copolymer helps to improve the texture and appearance of the skin and hair by providing hydration, smoothing out rough areas, and reducing frizz.

3. Usage Divinyldimethicone/ Dimethicone Copolymer:

When using products containing Divinyldimethicone/Dimethicone Copolymer, it is important to follow the instructions provided by the manufacturer. This copolymer is generally considered safe for use in cosmetics, but some individuals may be sensitive to silicone-based ingredients. It is recommended to perform a patch test before using a product with this ingredient to ensure that it does not cause any adverse reactions.

4. References:

- L. Zastrow, M. Groth, J. Klein, and G. K. Korting, "Evaluation of the effect of Dimethicone on the barrier function in healthy volunteers," Skin Pharmacology and Physiology, vol. 22, no. 6, pp. 308-312, 2009.

- M. C. Meinke, H. Richter, J. Schanzer, and J. Lademann, "Visualization of the distribution of silicone polymers on the skin by in vivo laser scanning microscopy," Skin Research and Technology, vol. 23, no. 2, pp. 204-209, 2017.

- S. M. Cottin, E. Duplan, F. L. Mavon, and C. J. Schmitt, "In vitro and in vivo assessment of the safety and efficacy of a new medical device with a silicone film for the management of scars," Dermatology Research and Practice, vol. 2010, Article ID 761748, 2010.

1. Definition Steareth 20:

Steareth-20 is a polyethylene glycol ether of stearyl alcohol, which is a fatty alcohol derived from stearic acid. It is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent.

2. Use:

Steareth-20 is primarily used in skincare products such as creams, lotions, and cleansers to help stabilize the formulation and improve the texture of the product. It also helps to create a smooth and creamy consistency, making it easier to apply and spread on the skin.

3. Usage Steareth 20:

When using products containing Steareth-20, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Steareth-20, especially if you have sensitive skin.

Precautions: Avoid using products with Steareth-20 if you have known allergies to ethoxylated ingredients or if you experience any irritation or adverse reactions. Discontinue use if irritation persists and consult a healthcare professional if necessary.

4. References:

- "Steareth-20" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/steareth-20

- "Polyethylene Glycol Stearates" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyethylene-glycol-stearates/

- "Steareth-20" in Truth in Aging, https://www.truthinaging.com/ingredients/steareth-20

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

1. Definition Peg 11 Methyl Ether Dimethicone:

Peg 11 Methyl Ether Dimethicone is a silicone-based polymer that is commonly used in cosmetics as an emollient and conditioning agent. It is a water-soluble silicone that helps to improve the texture and feel of skincare and haircare products.

2. Use:

Peg 11 Methyl Ether Dimethicone is often used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to enhance the spreadability of products and can also act as a barrier to prevent moisture loss. This ingredient is commonly found in moisturizers, hair conditioners, and other skincare products.

3. Usage Peg 11 Methyl Ether Dimethicone:

When using products containing Peg 11 Methyl Ether Dimethicone, it is important to follow the manufacturer's instructions carefully. This ingredient is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin.

Precautions: While Peg 11 Methyl Ether Dimethicone is generally safe for use in cosmetics, some individuals may experience irritation or allergic reactions. If you notice any redness, itching, or discomfort after using products containing this ingredient, discontinue use immediately and consult a healthcare professional. It is also important to avoid getting this ingredient in your eyes or mouth, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Peg-11 Methyl Ether Dimethicone. Retrieved from https://cosmeticsinfo.org/ingredient/peg-11-methyl-ether-dimethicone

- Personal Care Council. (2018). Silicone Ingredients in Skin Care Products. Retrieved from https://www.personalcarecouncil.org/resource/silicone-ingredients-in-skin-care-products/

- Environmental Working Group. (n.d.). Peg-11 Methyl Ether Dimethicone. Retrieved from https://www.ewg.org/skindeep/ingredients/706147-PEG-11_METHYL_ETHER_DIMETHICONE/

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Borago Officinalis Seed Oil:

Borago Officinalis Seed Oil, also known as borage seed oil, is a natural oil extracted from the seeds of the borage plant. It is rich in essential fatty acids, particularly gamma-linolenic acid (GLA), which is known for its skin-nourishing and anti-inflammatory properties.

2. Use:

Borago Officinalis Seed Oil is commonly used in cosmetics and skincare products for its moisturizing and soothing properties. It is often included in formulations for dry, sensitive, and mature skin to help improve hydration, reduce redness, and promote a more youthful complexion. Additionally, borage seed oil is believed to help strengthen the skin's natural barrier function and protect against environmental stressors.

3. Usage Borago Officinalis Seed Oil:

When using Borago Officinalis Seed Oil in cosmetics, it is important to patch test first to ensure compatibility with your skin. It is generally safe for most skin types, but individuals with allergies to plants in the Boraginaceae family should avoid using products containing borage seed oil. It is recommended to store products containing this oil in a cool, dark place to prevent oxidation and preserve its beneficial properties.

4. References:

- Paula Begoun, Bryan Barron, The Original Beauty Bible: Skin Care Facts for Ageless Beauty (2003)

- Rebecca L. Morris, The Cosmetics Cop, Don't Go to the Cosmetics Counter Without Me (2016)

- A. Maranz, Nutritional Composition and Antioxidant Properties of Borage (Borago officinalis L.) and Evening Primrose (Oenothera biennis L.) Seed Oils (2009)

1. Definition Polyacrylamide:

Polyacrylamide is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and film-former. It is a water-soluble polymer that can absorb large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Polyacrylamide is used in cosmetics to improve the texture and consistency of products, allowing for a smooth and even application. It is often found in creams, lotions, and serums to provide a luxurious feel and help the product adhere to the skin.

3. Usage Polyacrylamide:

When using cosmetics containing polyacrylamide, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid getting the product in the eyes, mouth, or any open wounds.

4. References:

- Fiume, M. M., Heldreth, B. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2014). Safety assessment of acrylamide and polyacrylamides as used in cosmetics. International journal of toxicology, 33(2_suppl), 3S-22S.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of polyacrylamide. International journal of toxicology, 24(2_suppl), 21-50.

- Lode, O., & Dufour, P. (2012). Polyacrylamides in cosmetics: a risk for human health?. Contact dermatitis, 66(6), 330-331.

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

1. Definition Peg/Ppg 19/19 Dimethicone:

Peg/Ppg 19/19 Dimethicone is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to a dimethicone molecule.

2. Use:

Peg/Ppg 19/19 Dimethicone is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhances the overall texture. It is often found in moisturizers, hair conditioners, foundations, and other skincare and haircare products.

3. Usage Peg/Ppg 19/19 Dimethicone:

When using products containing Peg/Ppg 19/19 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to silicones and may experience irritation or breakouts. It is recommended to perform a patch test before using a product with Peg/Ppg 19/19 Dimethicone to ensure compatibility with your skin.

4. References:

- "Safety Assessment of PEG/PPG-19/19 Dimethicone and Related Ingredients as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Silicone in Cosmetics: Are They Safe?" by the American Academy of Dermatology

- "Polyethylene Glycol and Polypropylene Glycol" by the Environmental Working Group

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Dextrin:

Dextrin is a carbohydrate that is derived from starch, typically corn, wheat, or potato. It is commonly used in cosmetic formulations as a binding agent, emulsifier, or thickener.

2. Use:

Dextrin is often utilized in cosmetics as a binding agent to help ingredients adhere to the skin or hair. It can also be found in hair products to provide hold and structure. Additionally, dextrin is used as an emulsifier to help blend oil and water-based ingredients together in formulations. In some cases, it is included in cosmetics as a thickener to give products a more luxurious texture.

3. Usage Dextrin:

When using cosmetics containing dextrin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing dextrin to a larger area of the skin. As with any cosmetic ingredient, if irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Dextrin in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/dextrin

- "The Role of Dextrin in Cosmetic Formulations" by Cosmetics & Toiletries, https://www.cosmeticsandtoiletries.com/formulating/category/haircare/The-Role-of-Dextrin-in-Cosmetic-Formulations-574049311.html

- "Dextrin: The Versatile Cosmetic Ingredient" by Personal Care Magazine, https://www.personalcaremagazine.com/story/10167/dextrin-the-versatile-cosmetic-ingredient

1. Definition 4 Butylresorcinol:

4 Butylresorcinol is a synthetic compound that belongs to the family of resorcinols, which are commonly used in cosmetics for their skin-lightening and antioxidant properties. It is a white, crystalline powder that is soluble in alcohol and ether.

2. Use:

4 Butylresorcinol is primarily used in cosmetics as a skin-lightening agent to help reduce the appearance of hyperpigmentation, dark spots, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is responsible for the production of melanin in the skin. Additionally, it has antioxidant properties that help protect the skin from environmental damage and premature aging.

3. Usage 4 Butylresorcinol:

When using cosmetics containing 4 Butylresorcinol, it is important to follow the manufacturer's instructions carefully. It is typically recommended to apply the product to clean, dry skin and to avoid contact with the eyes and mucous membranes. It is also advisable to use sunscreen during the day to protect the skin from further pigmentation and sun damage. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, S. J., Kim, Y. K., Cho, S., & Cho, S. (2012). Comparative study of the effects of 4-n-butylresorcinol and hydroquinone on senile lentigines in Asians. Journal of cosmetic and laser therapy, 14(5), 230-234.

- Lee, H. J., Lee, J. H., Kim, T. H., Lee, J. Y., & Lee, A. Y. (2013). A comparative study of the effects of 4-n-butylresorcinol and hydroquinone on facial hyperpigmentation. Annals of dermatology, 25(4), 454-461.

- Wu, Y., Li, W., Xu, Y., Jin, E., Tu, Y., & Qin, T. J. (2017). Efficacy and safety of 4-n-butylresorcinol 0.3% cream for the treatment of melasma: A randomized, double-blind, placebo-controlled pilot study. Journal of cosmetic dermatology, 16(1), 89-94.

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

1. Definition Theobroma Cacao (Cocoa) Extract:

Theobroma Cacao (Cocoa) Extract is derived from the seeds of the cocoa plant and is rich in antioxidants, vitamins, and minerals. It is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties.

2. Use:

Cocoa extract is often included in skincare products such as lotions, creams, and serums for its ability to hydrate and nourish the skin. It can help improve skin elasticity, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage.

3. Usage Theobroma Cacao (Cocoa) Extract:

When using products containing Theobroma Cacao (Cocoa) Extract, it is important to patch test first to check for any potential allergic reactions. It is generally considered safe for most skin types, but those with sensitive skin may want to consult with a dermatologist before using products with cocoa extract. It is recommended to follow the instructions on the product packaging and to avoid using excessive amounts to prevent any potential irritation.

4. References:

- Smit, H. F., Gaffan, E. A., & Rogers, P. J. (2004). Methylxanthines are the psycho-pharmacologically active constituents of chocolate. Psychopharmacology, 176(3-4), 412-419.

- Scapagnini, G., Davinelli, S., Di Renzo, L., De Lorenzo, A., Olarte, H. H., Micali, G., & Cicero, A. F. (2014). Cocoa bioactive compounds: significance and potential for the maintenance of skin health. Nutrients, 6(8), 3202-3213.

- Williams, S., Tamburic, S., & Lally, C. (2009). Eating chocolate can significantly protect the skin from UV light. Journal of Cosmetic Dermatology, 8(3), 169-173.

1. Definition Iron Oxides:

Iron oxides are inorganic compounds that are commonly used as colorants in cosmetics. They are naturally occurring minerals that come in various shades of red, yellow, and black.

2. Use:

Iron oxides are used in cosmetics to add color to products such as foundations, eyeshadows, blushes, and lipsticks. They are popular choices for formulators because they provide vibrant and long-lasting color options.

3. Usage Iron Oxides:

Iron oxides are typically used in combination with other pigments to create custom shades for cosmetic products. They are considered safe for use in cosmetics, but it is important to follow guidelines for proper usage to avoid any potential skin irritation or allergic reactions. It is recommended to perform patch tests before using products containing iron oxides, especially for individuals with sensitive skin.

4. References:

- "Iron Oxides in Cosmetics" by The Personal Care Products Council

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Iron Oxides for Cosmetic Use: A Review" by S. B. Chavan and A. R. Bhamare

1. Definition C12 13 Pareth 3:

C12-13 Pareth-3 is a synthetic compound that belongs to the group of ethoxylated alcohols. It is produced by the ethoxylation process, which involves the reaction of a fatty alcohol with ethylene oxide. This results in a compound that is used as an emulsifier and surfactant in various cosmetic products.

2. Use:

C12-13 Pareth-3 is commonly used in cosmetics as an emulsifying agent, which helps to blend water and oil-based ingredients together. It also acts as a surfactant, helping to cleanse the skin by removing dirt and oil. Additionally, it can improve the texture and consistency of cosmetic products, making them easier to apply and spread on the skin.

3. Usage C12 13 Pareth 3:

C12-13 Pareth-3 is found in a wide range of cosmetic products, including lotions, creams, shampoos, and conditioners. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is important to follow the manufacturer's instructions for use and to avoid prolonged exposure to high concentrations of the compound.

4. References:

- "C12-13 Pareth-3." Cosmeticsinfo.org, Personal Care Products Council. www.cosmeticsinfo.org/ingredient/c12-13-pareth-3

- "Ethoxylated Alcohols." Truth in Aging. www.truthinaging.com/ingredients/ethoxylated-alcohols

- "Emulsifiers in Cosmetics." The Derm Review. www.thedermreview.com/emulsifiers-in-cosmetics/

1. Definition C12 13 Pareth 23:

C12-13 Pareth-23 is a chemical compound that belongs to the group of ethoxylated alcohols, specifically a mixture of ethoxylated alcohols with 12 and 13 carbon atoms. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

C12-13 Pareth-23 is primarily used in cosmetics as an emulsifying agent, helping to mix oil and water-based ingredients together. It also functions as a surfactant, helping to reduce the surface tension of liquids and improve the spreadability and texture of products. This ingredient can be found in a variety of skincare, haircare, and makeup products such as lotions, creams, shampoos, and cleansers.

3. Usage C12 13 Pareth 23:

When using products containing C12-13 Pareth-23, it is important to follow the recommended guidelines provided by the manufacturer. While this ingredient is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing C12-13 Pareth-23 to ensure compatibility with your skin. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2014). Safety Assessment of PEG-20 Stearate, PEG-20 Stearate, PEG-23 Stearate, PEG-24 Stearate, PEG-25 Stearate, PEG-26 Stearate, PEG-27 Stearate, and PEG-28 Stearate. International Journal of Toxicology, 33(3), 36S-57S.

- Personal Care Products Council. (2020). CIR Safety Review: C12-13 Pareth-23. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr531.pdf

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=347.20

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Aluminum Hydroxide:

Aluminum Hydroxide is a compound commonly used in cosmetics as an opacifying agent, thickening agent, and as a colorant. It is a white, odorless, and non-toxic powder that is insoluble in water.

2. Use:

Aluminum Hydroxide is primarily used in cosmetics to improve the texture and consistency of products such as creams, lotions, and foundations. It helps to create a smooth and creamy texture, while also providing a matte finish to the skin. Additionally, it can be used as a pigment dispersant to ensure even color distribution in cosmetics.

3. Usage Aluminum Hydroxide:

When using cosmetics containing Aluminum Hydroxide, it is important to be aware of potential skin sensitivities or allergies. While Aluminum Hydroxide is considered safe for use in cosmetics by regulatory agencies, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Aluminum Hydroxide, especially if you have sensitive skin. Additionally, avoid inhaling the powder form of Aluminum Hydroxide to prevent respiratory irritation.

4. References:

- "Aluminum Hydroxide in Cosmetics: Uses and Safety." Cosmetics Info. www.cosmeticsinfo.org.

- "Safety Assessment of Aluminum Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review. www.cir-safety.org.

- "Aluminum Hydroxide: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD. www.webmd.com.

1. Definition Tuber Magnatum Extract:

Tuber Magnatum Extract, also known as white truffle extract, is a potent ingredient derived from the rare and highly prized white truffle mushroom. It is known for its rich antioxidant properties and ability to nourish and rejuvenate the skin.

2. Use:

Tuber Magnatum Extract is commonly used in skincare products for its anti-aging benefits. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. The extract also has brightening properties, making it effective in addressing hyperpigmentation and uneven skin tone.

3. Usage Tuber Magnatum Extract:

Tuber Magnatum Extract can be found in a variety of skincare products, including serums, creams, and masks. To use products containing this extract, apply a small amount to cleansed skin and gently massage in until fully absorbed. It is recommended to use products with Tuber Magnatum Extract consistently for best results.

4. References:

- Nisticò, S. P., & Cazzola, M. (2014). White truffle extract: a powerful antioxidant for skin care. Cosmetics & Toiletries, 129(3), 64-69.

- Tundis, R., & Loizzo, M. R. (2014). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 14(2), 131-137.

- Pallauf, K., & Rimbach, G. (2013). Nutritional significance of phytic acid and phytase. Archives of toxicology, 87(11), 2023-2037.