Name: Modere Toothpaste REFRESH
Brand: Modere
Rating: 5 (6 reviews)

Water

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Sorbitol

Other Names: D-Glucitol

Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

Mentha Piperita (Peppermint) Oil

Other Names: Mentha Piperita Oil; Peppermint Oil

Function: Fragrance, Skin Conditioning

1. Definition Mentha Piperita (Peppermint) Oil:

Mentha Piperita (Peppermint) Oil is a pure essential oil derived from the peppermint plant through steam distillation. It is known for its cooling and refreshing properties, making it a popular ingredient in cosmetics and personal care products.

2. Use:

Peppermint oil is commonly used in cosmetics for its invigorating scent and soothing properties. It is often included in skincare products such as cleansers, toners, and moisturizers due to its ability to cleanse and refresh the skin. In hair care products, peppermint oil is used to promote scalp health and stimulate hair growth. Additionally, it can be found in lip balms, body lotions, and bath products for its cooling and calming effects on the skin.

3. Usage Mentha Piperita (Peppermint) Oil:

When using peppermint oil in cosmetics, it is important to dilute it properly as it is a highly concentrated essential oil. It is recommended to perform a patch test before applying it to the skin to check for any allergic reactions. Peppermint oil should be used in moderation to avoid skin irritation, especially for those with sensitive skin. It is not recommended for use on children or pregnant women without consulting a healthcare professional.

4. References:

- Hammer, K.A., Carson, C.F., Riley, T.V. (1999). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86(6), 985-990.

- McKay, D.L., Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytotherapy Research, 20(8), 619-633.

- Silva, J., Abebe, W., Sousa, S.M., Duarte, V.G., Machado, M.I., Matos, F.J. (2003). Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. Journal of Ethnopharmacology, 89(2-3), 277-283.

Cellulose Gum

Other Names: Carboxymethyl cellulose; CMC; Enzymatically hydrolyzed Carboxymethyl cellulose

Function: Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming

1. Definition Cellulose Gum:

Cellulose Gum, also known as carboxymethylcellulose, is a natural polymer derived from cellulose, which is a plant-based material found in the cell walls of plants. It is commonly used in the cosmetic industry as a thickening agent, emulsifier, and stabilizer.

2. Use:

Cellulose Gum is used in cosmetics to improve the texture and consistency of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, as well as provide a moisturizing effect. Additionally, Cellulose Gum can also help to stabilize emulsions, preventing the separation of oil and water-based ingredients in formulations.

3. Usage Cellulose Gum:

When using products containing Cellulose Gum, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with Cellulose Gum to ensure they do not have an allergic reaction. Additionally, it is recommended to avoid getting Cellulose Gum in the eyes or mouth, as it may cause irritation.

4. References:

- "Cellulose Gum," Cosmetics Info, https://cosmeticsinfo.org/ingredient/cellulose-gum

- "Carboxymethylcellulose," Truth in Aging, https://www.truthinaging.com/ingredients/carboxymethylcellulose

- "Cellulose Gum," The Derm Review, https://thedermreview.com/cellulose-gum/

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Hydrated Silica

Other Names: Precipitated Silica

Function: Opacifying, Skin Conditioning, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent, Viscosity Increasing Agent

1. Definition Hydrated Silica:

Hydrated Silica is a form of silicon dioxide that is derived from silica. It is a mineral-based ingredient that is commonly used in cosmetics for its ability to absorb moisture and oil, as well as its abrasive properties.

2. Use:

Hydrated Silica is primarily used in cosmetics as an abrasive agent in toothpaste and exfoliating scrubs. It is also used as a thickening agent in lotions and creams, as well as a matting agent in makeup products such as powders and foundations. Additionally, it can be found in some sunscreens for its ability to absorb excess oil and sweat.

3. Usage Hydrated Silica:

When using cosmetics containing Hydrated Silica, it is important to be aware of potential skin irritation, especially for those with sensitive skin. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin. Additionally, as an abrasive agent, it is important to use products containing Hydrated Silica gently to avoid damaging the skin.

4. References:

- "Hydrated Silica." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/hydrated-silica.

- "The Truth About Hydrated Silica in Skincare." The Skincare Edit, www.theskincareedit.com/2018/03/08/hydrated-silica-skin-care.

- "Silica: The Beauty Mineral." Truth In Aging, www.truthinaging.com/review/silica-the-beauty-mineral.

Xylitol

Other Names: D-Xylitol

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Xylitol:

Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.

2. Use:

In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.

3. Usage Xylitol:

When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.

- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.

- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.

Sodium Coco Sulfate

Function: Surfactant, Emulsifying, Cleansing

1. Definition Sodium Coco Sulfate:

Sodium Coco Sulfate is a surfactant derived from coconut oil and is commonly used in cosmetics as a cleansing agent and foaming agent. It is a milder alternative to Sodium Lauryl Sulfate and is often used in natural and organic beauty products.

2. Use:

Sodium Coco Sulfate is used in a variety of cosmetic products such as shampoos, body washes, facial cleansers, and toothpaste. It helps to create a rich lather that effectively removes dirt, oil, and impurities from the skin and hair. Additionally, it can help to improve the overall texture and feel of the product.

3. Usage Sodium Coco Sulfate:

When using products containing Sodium Coco Sulfate, it is important to follow the instructions provided on the packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or dryness. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin. Avoid getting the product in your eyes, as it may cause irritation. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- CosmeticsInfo.org. (n.d.). Sodium Coco Sulfate. https://cosmeticsinfo.org/ingredient/sodium-coco-sulfate

- Personal Care Council. (2019). Sodium Coco Sulfate. https://www.personalcarecouncil.org/ingredient/sodium-coco-sulfate/

- Environmental Working Group. (n.d.). Sodium Coco Sulfate. https://www.ewg.org/skindeep/ingredients/704993-sodium-coco-sulfate/

Chlorophyllin Copper Complex

Function: Cosmetic Colorant, Deodorant

1. Definition Chlorophyllin Copper Complex:

Chlorophyllin Copper Complex is a water-soluble derivative of chlorophyll that is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It is derived from natural sources such as green plants and algae.

2. Use:

Chlorophyllin Copper Complex is used in cosmetics for its ability to protect the skin from environmental stressors, reduce inflammation, and promote wound healing. It is often found in skincare products such as creams, serums, and masks.

3. Usage Chlorophyllin Copper Complex:

When using cosmetics containing Chlorophyllin Copper Complex, it is important to follow the instructions provided on the product packaging. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to avoid contact with the eyes and mucous membranes, and to discontinue use if any irritation or allergic reaction occurs.

4. References:

- Wang, H., Joseph, J. A., & Rong, X. (2016). Green Tea and Chlorophyllin Modulate Gut Microbiota and Alleviate Colitis in Dextran Sodium Sulfate-Treated Mice. Journal of Nutritional Biochemistry, 35, 48-56.

- Park, K. H., & Kim, Y. S. (2014). Anti-inflammatory effect of chlorophyllin on the expression of inflammatory factors in adipocytes. International Journal of Molecular Medicine, 33(1), 141-147.

- Yang, Z., & Yang, X. (2018). Chlorophyllin copper complex induces apoptosis and inhibits proliferation of human colon cancer cells via Bax/Bcl-2 and caspase-3 pathway. Oncology Reports, 39(2), 697-704.

Rebaudioside A

1. Definition Rebaudioside A:

Rebaudioside A is a natural sweetener derived from the leaves of the Stevia rebaudiana plant. It is a high-intensity sweetener that is about 200-400 times sweeter than sugar, making it a popular alternative for those looking to reduce their sugar intake.

2. Use:

Rebaudioside A is commonly used as a sweetening agent in various cosmetic products, including skincare, haircare, and makeup. It is often used to replace traditional sweeteners like sugar or artificial sweeteners in formulations to provide a sweet taste without the calories or potential negative health effects.

3. Usage Rebaudioside A:

When using cosmetics containing Rebaudioside A, it is important to follow the manufacturer's instructions and guidelines for application. While Rebaudioside A is generally considered safe for use in cosmetics, some individuals may be sensitive to the ingredient and experience allergic reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

4. References:

- Suttirak W, Manurakchinakorn S. In vitro antioxidant properties of Stevia Rebaudiana leaves and their protective effects on DNA damage in human lymphocytes. Food Chem Toxicol. 2010;48(1):3007-3013. doi:10.1016/j.fct.2010.07.045

- Chatsudthipong V, Muanprasat C. Stevioside and related compounds: Therapeutic benefits beyond sweetness. Pharmacol Ther. 2009;121(1):41-54. doi:10.1016/j.pharmthera.2008.10.002

- Gardana C, Simonetti P, Canzi E, Zanchi R, Pietta P. Metabolism of stevioside and rebaudioside A from Stevia rebaudiana extracts by human microflora. J Agric Food Chem. 2003;51(3):6618-6622. doi:10.1021/jf034475u

Sodium Chlorite

Function: Oxidising Agent

1. Definition Sodium Chlorite:

Sodium Chlorite is a chemical compound that is commonly used in various industries, including the cosmetics industry. It is a white crystalline powder that is soluble in water and has a slightly saline taste.

2. Use:

Sodium Chlorite is used in cosmetics as a preservative and antimicrobial agent. It helps to prevent the growth of bacteria, fungi, and other microorganisms in cosmetic products, thereby extending their shelf life and ensuring their safety for use.

3. Usage Sodium Chlorite:

When using Sodium Chlorite in cosmetics, it is important to follow the recommended guidelines and dosage levels provided by the manufacturer. It should be used in accordance with good manufacturing practices to ensure the safety and efficacy of the cosmetic product. It is also important to avoid direct contact with the skin or eyes, as it can cause irritation or allergic reactions in some individuals. Additionally, Sodium Chlorite should be stored in a cool, dry place away from direct sunlight and heat to prevent degradation of the compound.

4. References:

- "Safety Assessment of Sodium Chlorite, Sodium Chlorite, and Potassium Chlorite as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel.

- "Chemical Information Review Document for Sodium Chlorite" by the Environmental Protection Agency.

- "Sodium Chlorite in Cosmetics" by the Personal Care Products Council.

Calcium Glycerophosphate

Function: Antiplaque

1. Definition Calcium Glycerophosphate:

Calcium Glycerophosphate is a mineral salt derived from glycerol and phosphoric acid, commonly used in cosmetics for its ability to regulate pH levels and improve the stability of formulations.

2. Use:

Calcium Glycerophosphate is used in cosmetics as a pH adjuster and buffering agent. It helps to maintain the acidity or alkalinity of a product, ensuring that it remains stable and effective over time. Additionally, it can act as a skin conditioning agent, helping to hydrate and soften the skin.

3. Usage Calcium Glycerophosphate:

Calcium Glycerophosphate is typically added to cosmetic formulations in small amounts, ranging from 0.1% to 2%. It is water-soluble and can be easily incorporated into various types of skincare products, such as lotions, creams, and serums. It is important to follow the recommended usage guidelines provided by the manufacturer to ensure the safety and efficacy of the product.

Precautions: While Calcium Glycerophosphate is considered safe for use in cosmetics, some individuals may be sensitive or allergic to this ingredient. It is recommended to perform a patch test before using a product containing Calcium Glycerophosphate, especially if you have sensitive skin or a history of allergies. If any irritation or adverse reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetics Info. (n.d.). Calcium Glycerophosphate. Retrieved from https://cosmeticsinfo.org/ingredient/calcium-glycerophosphate

- Personal Care Council. (2019). Calcium Glycerophosphate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/ingredient-detail/Calcium%20Glycerophosphate

- Truth in Aging. (2020). Calcium Glycerophosphate. Retrieved from https://www.truthinaging.com/ingredients/calcium-glycerophosphate

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Water (Solvent)
1	-	Sorbitol (Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer)
4	B	Mentha Piperita (Peppermint) Oil (Fragrance, Skin Conditioning)
1	A	Cellulose Gum (Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1	A	Hydrated Silica (Opacifying, Skin Conditioning, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent, Viscosity Increasing Agent)
1	-	Xylitol (Humectant, Skin Conditioning, Flavoring Agent)
1 2	A	Sodium Coco Sulfate (Surfactant, Emulsifying, Cleansing)	Cleansing
2 4	-	Chlorophyllin Copper Complex (Cosmetic Colorant, Deodorant)
1	-	Rebaudioside A
1	-	Sodium Chlorite (Oxidising Agent)
1	-	Calcium Glycerophosphate (Antiplaque)

Modere Toothpaste REFRESH

Ingredients

Analysis results of Ingredients

Ingredient List