MyChelle Perfect C Serum

1. Definition Water:

2. Use:

3. Usage Water:

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Polyglyceryl 4 Caprate:

2. Use:

3. Usage Polyglyceryl 4 Caprate:

4. References:

- "Polyglyceryl-4 Caprate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-4-caprate.

- Yoon, Juyoung, et al. "Safety assessment of polyglyceryl fatty acid esters as used in cosmetics." International Journal of Toxicology, vol. 34, no. 5, 2015, pp. 463-482.

- "Polyglyceryl-4 Caprate." Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-4-caprate.

1. Definition Ergothioneine:

2. Use:

3. Usage Ergothioneine:

4. References:

- Paula, L., et al. (2019). Ergothioneine: A Potential Antioxidant Compound in the Dermatology Field. Dermatology and Therapy, 9(2), 223-232.

- Cheah, I. K., & Halliwell, B. (2012). Ergothioneine; antioxidant potential, physiological function and role in disease. Biochimica et Biophysica Acta, 1822(5), 784-793.

- Gründemann, D., et al. (2005). Discovery of the ergothioneine transporter. Proceedings of the National Academy of Sciences, 102(14), 5256-5261.

1. Definition Buddleja Davidii Meristem Cell Culture:

2. Use:

3. Usage Buddleja Davidii Meristem Cell Culture:

4. References:

- Kim, Y. J., Uyama, H., & Kobayashi, S. (2006). Inhibition effects of Buddleja officinalis on melanin biosynthesis. Natural product research, 20(1), 86-90.

- Li, W., Li, Y., & Yang, R. (2012). Antioxidant activity of extracts and fractions from Buddleja davidii. Food chemistry, 134(4), 2040-2046.

- Lee, S. H., & Kim, J. K. (2013). Buddleja officinalis extract inhibits UV-B-induced matrix metalloproteinase-1 expression in human dermal fibroblasts. Journal of medicinal food, 16(6), 511-517.

1. Definition Solanum Lycopersicum (Tomato) Fruit Lipids:

2. Use:

3. Usage Solanum Lycopersicum (Tomato) Fruit Lipids:

4. References:

- Bohn T, Carotenoids and Flavonoids Contribute to Nutritional Protection against Skin Damage from Sunlight. (2019)

- Kim J, et al. Lycopene Inhibits ICAM-1 Expression and NF-κB Activation by Nrf2-Regulated Heme Oxygenase-1 in Aged Rat Kidney. (2019)

- Yamamoto Y, et al. Tomato Extract Suppresses UV-Induced Skin Aging. (2020)

1. Definition Citrus Reticulata (Tangerine) Peel Oil:

2. Use:

3. Usage Citrus Reticulata (Tangerine) Peel Oil:

4. References:

- Kim, J., Kim, H. J., & Kim, J. Y. (2017). Citrus reticulata Blanco peel essential oil attenuates DMBA/TPA-induced skin tumorigenesis by inhibiting cell proliferation and inflammation in mice. Journal of Food and Drug Analysis, 25(4), 817-825.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2010). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermal Science, 58(2), 115-122.

- Li, Y., Wang, Y., Chen, Y., & Li, P. (2019). Chemical composition and anti-inflammatory and antioxidant activities of eight citrus essential oils. Journal of Food Science and Technology, 56(6), 3109-3117.

1. Definition Lavandula Angustifolia (Lavender) Oil:

2. Use:

3. Usage Lavandula Angustifolia (Lavender) Oil:

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Citrus Paradisi (Grapefruit) Peel Oil:

2. Use:

3. Usage Citrus Paradisi (Grapefruit) Peel Oil:

4. References:

- Cho, E., Chung, E., Lim, K. M., & Lim, C. Y. (2014). Grapefruit seed extract as a natural preservative in cosmetics. Journal of Cosmetic Science, 65(3), 153-163.

- Kim, S., Kim, S., & Lee, J. (2017). Anti-inflammatory effects of grapefruit peel oil in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 46(5), 618-624.

- Garg, A., Garg, S., Zaneveld, L. J. D., & Singla, A. K. (2001). Chemistry and pharmacology of the Citrus bioflavonoid hesperidin. Phytotherapy Research, 15(8), 655-669.

1. Definition Elaeis Guineensis (Palm) Oil:

2. Use:

3. Usage Elaeis Guineensis (Palm) Oil:

4. References:

- Akihisa, T., Yasukawa, K., Yamaura, M., Ukiya, M., Kimura, Y., Shimizu, N., Arai, K., and T. Tamura. (2001). Triterpene Alcohol and Sterol Ferulates from Rice Bran and Their Anti-inflammatory Effects. Journal of Agricultural and Food Chemistry, 49(8), 4087-4091.

- Ng, C. Y., Kamisah, Y., Faizah, O., and A. Jaarin. (2014). The role of palm oil and its constituents in blood pressure regulation. Journal of Food and Drug Analysis, 22(1), 147-160.

- Sundram, K., Sambanthamurthi, R., and Y. Tan. (2003). Palm fruit chemistry and nutrition. Asia Pacific Journal of Clinical Nutrition, 12(3), 355-362.

1. Definition Fructooligosaccharides:

2. Use:

3. Usage Fructooligosaccharides:

4. References:

- Roberfroid, M. B. (2007). Inulin-type fructans: functional food ingredients. The Journal of Nutrition, 137(11), 2493S-2502S.

- Schrezenmeir, J., & de Vrese, M. (2001). Probiotics, prebiotics, and synbiotics—approaching a definition. The American Journal of Clinical Nutrition, 73(2), 361s-364s.

- Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417-1435.

1. Definition Beta Carotene:

2. Use:

3. Usage Beta Carotene:

4. References:

- Bhosale, P., & Serban, B. (2017). Cosmetic benefits of astaxanthin on humans subjects. Acta Biochimica Polonica, 64(3), 507-512.

- Darvin, M. E., Sterry, W., Lademann, J., & Patzelt, A. (2014). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 196-201.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

1. Definition Glucosamine Hcl:

2. Use:

3. Usage Glucosamine Hcl:

4. References:

- Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

- Bissett, D. L., et al. (2007). Glucosamine: an ingredient with skin and other benefits. Journal of Cosmetic Dermatology, 6(4), 309-315.

- Kim, S. H., et al. (2009). Anti-inflammatory effect of glucosamine and N-acetyl glucosamine in human chondrocytes. Journal of Pharmacological Sciences, 109(3), 399-407.

1. Definition Wine Extract:

2. Use:

3. Usage Wine Extract:

4. References:

- Batiha, Gaber El-Saber, et al. "Grape Extracts as Antioxidants for Food Preservation and Health Benefits." Antioxidants 9.4 (2020): 325.

- Cho, Su-Jin, et al. "Effect of Red Wine Extract on Oxidative Stress and Inflammatory Cytokines in Korean Adults." Journal of the Korean Society of Food Science and Nutrition 44.11 (2015): 1682-1688.

- Ndiaye, Mary, et al. "The Grape Antioxidant Resveratrol for Skin Disorders: Promise, Prospects, and Challenges." Archives of Biochemistry and Biophysics 508.2 (2011): 164-170.

1. Definition Astaxanthin:

2. Use:

3. Usage Astaxanthin:

4. References:

- Tominaga K, Hongo N, Karato M, Yamashita E. Cosmetic benefits of astaxanthin on humans subjects. Acta Biochim Pol. 2012;59(1):43-7.

- Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in skin health, repair, and disease: A comprehensive review. Nutrients. 2018;10(4):522.

- Camera E, Mastrofrancesco A, Fabbri C, et al. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol. 2009;18(3):222-31.

1. Definition Tocotrienols:

2. Use:

3. Usage Tocotrienols:

4. References:

- Shahidi F, Ambigaipalan P. (2015). Tocopherols and Tocotrienols in Common and Emerging Dietary Sources: Occurrence, Applications, and Health Benefits.

- Serbinova E, Kagan V, Han D, Packer L. (1991). Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.

- Packer L, Weber SU, Rimbach G. (2001). Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling.

1. Definition Caprylic/ Capric Triglyceride:

2. Use:

3. Usage Caprylic/ Capric Triglyceride:

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Tocopherol, D Alpha:

2. Use:

3. Usage Tocopherol, D Alpha:

4. References:

- Lin, J. T., & Jacob, R. F. (2012). Vitamin E in human skin: organ-specific physiology and considerations for its use in dermatology. Molecular aspects of medicine, 33(1), 57-66.

- Thiele, J. J., Hsieh, S. N., & Ekanayake-Mudiyanselage, S. (2005). Vitamin E: critical review of its current use in cosmetic and clinical dermatology. Dermatologic surgery, 31(s1), 805-813.

- Keen, M. A., & Hassan, I. (2016). Vitamin E in dermatology. Indian dermatology online journal, 7(4), 311.

1. Definition Ubiquinone:

2. Use:

3. Usage Ubiquinone:

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.

1. Definition Benzyl Alcohol:

2. Use:

3. Usage Benzyl Alcohol:

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.

- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol

1. Definition Xanthan Gum:

2. Use:

3. Usage Xanthan Gum:

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Linalool:

2. Use:

3. Usage Linalool:

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.

1. Definition Limonene:

2. Use:

3. Usage Limonene:

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.

1. Definition Citral:

2. Use:

3. Usage Citral:

4. References:

- Gomes-Carneiro, M. R., Dias, D. M., Paumgartten, F. J., & Azevedo, R. B. (2005). Subchronic toxicity of citral in rats. Food and Chemical Toxicology, 43(9), 1361-1367.

- Prashar, A., Locke, I. C., & Evans, C. S. (2004). Cytotoxicity of citral and limonene in a human melanoma cell line. Phytomedicine, 11(1), 34-40.

- Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26(9-10), 1231-1237.