NEOGEN Code9 Honey Cera BB Cream

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Disteardimonium Hectorite:

Disteardimonium Hectorite is a synthetic clay mineral derived from hectorite clay. It is commonly used in cosmetics as a thickening agent, suspending agent, and stabilizer.

2. Use:

Disteardimonium Hectorite is primarily used in cosmetics to create a smooth and creamy texture in products such as foundations, concealers, and creams. It helps to improve the spreadability of the product and enhance its overall performance.

3. Usage Disteardimonium Hectorite:

When using products containing Disteardimonium Hectorite, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid inhaling the powder form of Disteardimonium Hectorite to prevent irritation to the respiratory system.

4. References:

- "Safety Assessment of Disteardimonium Hectorite as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Evaluation of the Skin Irritation Potential of Disteardimonium Hectorite" by the Journal of Cosmetic Science

- "Formulation and Characterization of Disteardimonium Hectorite-Based Cosmetic Products" by the International Journal of Cosmetic Science

1. Definition Isododecane:

Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.

2. Use:

Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.

3. Usage Isododecane:

When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.

4. References:

- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.

- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.

- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf

1. Definition Propylene Carbonate:

Propylene Carbonate is a synthetic solvent commonly used in cosmetics. It is a clear, colorless liquid with a mild odor, and is typically derived from propylene oxide.

2. Use:

Propylene Carbonate is used in cosmetics as a solvent and carrier agent for various ingredients. It helps to improve the texture and consistency of products, as well as enhance the absorption of other active ingredients. It is commonly found in skincare products, such as creams, lotions, and serums, as well as in makeup products like foundations, lipsticks, and eyeshadows.

3. Usage Propylene Carbonate:

When using products containing Propylene Carbonate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Propylene Carbonate, especially if you have sensitive skin. Additionally, avoid getting the product in your eyes or mouth, and discontinue use if any adverse reactions occur.

4. References:

- "Propylene Carbonate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/propylene-carbonate.

- "Propylene Carbonate." The Dermatology Review, www.thedermreview.com/propylene-carbonate/.

- "Safety Assessment of Propylene Carbonate as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/PCarbonate1114SLR.pdf.

1. Definition Octyldodecanol:

Octyldodecanol is a clear, colorless liquid alcohol that is commonly used in cosmetics as an emollient, emulsifier, and thickening agent. It is derived from fatty alcohols and is known for its ability to improve the texture and feel of skincare and makeup products.

2. Use:

Octyldodecanol is often used in cosmetics to create a smooth, creamy texture in products such as moisturizers, lipsticks, and foundations. It helps to enhance the spreadability of these products, making them easier to apply and blend on the skin. Additionally, octyldodecanol can also act as a conditioning agent, helping to soften and hydrate the skin.

3. Usage Octyldodecanol:

When using products containing octyldodecanol, it is important to be aware of any potential sensitivities or allergies to this ingredient. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, individuals with sensitive skin may want to avoid products with high concentrations of octyldodecanol to prevent irritation.

4. References:

- "Octyldodecanol." Cosmetics Info, www.cosmeticsinfo.org/ingredient/octyldodecanol.

- "Octyldodecanol." The Derm Review, www.thedermreview.com/octyldodecanol/.

- "Octyldodecanol." Truth In Aging, www.truthinaging.com/ingredients/octyldodecanol.

1. Definition Triethoxycaprylylsilane:

Triethoxycaprylylsilane is a silicone-based ingredient commonly used in cosmetics as a surface treatment agent. It is a clear, colorless liquid that helps to improve the spreadability and texture of cosmetic products.

2. Use:

Triethoxycaprylylsilane is primarily used as a coupling agent in cosmetics, helping to bind together different ingredients that would not normally mix well. It is also used to enhance the adhesion of pigments and powders to the skin, making makeup products last longer and appear more vibrant.

3. Usage Triethoxycaprylylsilane:

Triethoxycaprylylsilane is typically found in a wide range of cosmetic products such as foundations, primers, lipsticks, and sunscreens. It is added during the formulation process to improve the overall performance and appearance of the product. When using cosmetics containing Triethoxycaprylylsilane, it is important to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- "Safety Assessment of Triethoxycaprylylsilane as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2018)

- "Silanes and Other Coupling Agents, Volume 3" by George Wypych (2016)

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach (2001)

1. Definition Aluminum Hydroxide:

Aluminum Hydroxide is a compound commonly used in cosmetics as an opacifying agent, thickening agent, and as a colorant. It is a white, odorless, and non-toxic powder that is insoluble in water.

2. Use:

Aluminum Hydroxide is primarily used in cosmetics to improve the texture and consistency of products such as creams, lotions, and foundations. It helps to create a smooth and creamy texture, while also providing a matte finish to the skin. Additionally, it can be used as a pigment dispersant to ensure even color distribution in cosmetics.

3. Usage Aluminum Hydroxide:

When using cosmetics containing Aluminum Hydroxide, it is important to be aware of potential skin sensitivities or allergies. While Aluminum Hydroxide is considered safe for use in cosmetics by regulatory agencies, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Aluminum Hydroxide, especially if you have sensitive skin. Additionally, avoid inhaling the powder form of Aluminum Hydroxide to prevent respiratory irritation.

4. References:

- "Aluminum Hydroxide in Cosmetics: Uses and Safety." Cosmetics Info. www.cosmeticsinfo.org.

- "Safety Assessment of Aluminum Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review. www.cir-safety.org.

- "Aluminum Hydroxide: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD. www.webmd.com.

1. Definition Alumina:

Alumina, also known as aluminum oxide, is a naturally occurring mineral that is commonly used in cosmetics for its abrasive and absorbent properties. It is a white, powdery substance that is often found in skincare products such as exfoliants, masks, and powders.

2. Use:

Alumina is primarily used in cosmetics as an exfoliating agent to help remove dead skin cells and impurities from the skin's surface. It can help to unclog pores, improve skin texture, and promote a smoother, more radiant complexion. Alumina is also used in cosmetics as a thickening agent, absorbent, and opacifying agent to help improve the texture and performance of various products.

3. Usage Alumina:

When using cosmetics containing alumina, it is important to follow the manufacturer's instructions carefully. Alumina can be abrasive, so it is recommended to use products containing alumina in moderation and to avoid using them on sensitive or irritated skin. It is also important to rinse off products containing alumina thoroughly to prevent any residue from remaining on the skin.

4. References:

- "Aluminum Oxide." Cosmetics Info, www.cosmeticsinfo.org/ingredient/aluminum-oxide.

- "Aluminum Oxide." Truth in Aging, www.truthinaging.com/ingredients/aluminum-oxide.

- "Alumina." Personal Care Council, www.personalcarecouncil.org/ingredient-info/alumina.

1. Definition Ozokerite:

Ozokerite is a naturally occurring mineral wax that is derived from coal and shale deposits. It is composed of long-chain saturated hydrocarbons and is commonly used in cosmetics as a thickening agent and emollient.

2. Use:

Ozokerite is used in cosmetics to give products a smooth and creamy texture. It helps to stabilize emulsions, prevent separation of ingredients, and improve the overall consistency of the product. Ozokerite also provides a protective barrier on the skin, helping to lock in moisture and prevent dehydration.

3. Usage Ozokerite:

Ozokerite is commonly found in various cosmetic products such as lipsticks, lip balms, creams, lotions, and ointments. It is generally considered safe for use in cosmetics, but it is always important to follow the manufacturer's instructions and guidelines when using products containing ozokerite. Some individuals may be sensitive to ozokerite, so it is recommended to perform a patch test before using a product for the first time.

4. References:

- "Ozokerite in Cosmetics: Uses and Safety." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/ozokerite.

- "Ozokerite Wax." MakingCosmetics Inc., www.makingcosmetics.com/Ozokerite-Wax_p_119.html.

- "Ozokerite." Truth in Aging, www.truthinaging.com/ingredients/ozokerite.

1. Definition Polyhydroxystearic Acid:

Polyhydroxystearic Acid is a synthetic ingredient commonly used in cosmetics as an emulsifier and stabilizer. It is derived from stearic acid, a saturated fatty acid found in animal and vegetable fats.

2. Use:

Polyhydroxystearic Acid is primarily used in cosmetics as an emulsifier to help mix oil and water-based ingredients together. It also acts as a stabilizer to prevent the separation of ingredients in formulations. Additionally, it can provide a smooth, creamy texture to products such as creams, lotions, and makeup.

3. Usage Polyhydroxystearic Acid:

Polyhydroxystearic Acid is considered safe for use in cosmetics, but like any other cosmetic ingredient, it is important to follow recommended guidelines for usage. It is typically used in concentrations ranging from 0.5% to 5% in formulations. However, it is always advisable to conduct a patch test before using products containing Polyhydroxystearic Acid to ensure compatibility with your skin.

4. References:

- "Polyhydroxystearic Acid" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/polyhydroxystearic-acid)

- "Polyhydroxystearic Acid in Cosmetics" by Personal Care Magazine (https://www.personalcaremagazine.com/story/10410/polyhydroxystearic-acid-in-cosmetics)

- "Safety Assessment of Polyhydroxystearic Acid" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/polyhydroxystearic%20acid.pdf)

1. Definition Zinc Oxide:

Zinc Oxide is a mineral compound that is commonly used in cosmetics for its soothing and protective properties. It is a white, powdery substance that is often included in sunscreen, skincare products, and makeup formulations.

2. Use:

Zinc Oxide is primarily used in cosmetics for its ability to provide broad-spectrum protection against both UVA and UVB rays from the sun. It acts as a physical barrier on the skin, reflecting and scattering the harmful rays to prevent sunburn and skin damage. In addition to its sun protection benefits, Zinc Oxide also has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Zinc Oxide:

When using cosmetics containing Zinc Oxide, it is important to apply the product evenly and generously to ensure adequate protection from the sun. Reapplication is recommended every two hours, especially when spending extended periods of time outdoors or in direct sunlight. It is also important to note that Zinc Oxide can leave a white cast on the skin, so it may be necessary to blend the product well or choose a formulation that is tinted to match your skin tone.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.

- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.

- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.

1. Definition Sorbitan Isostearate:

Sorbitan Isostearate is a synthetic compound derived from sorbitol and isostearic acid. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Isostearate is primarily used in cosmetics as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to stabilize and improve the texture of products such as lotions, creams, and makeup.

3. Usage Sorbitan Isostearate:

Sorbitan Isostearate is considered safe for use in cosmetics and personal care products when used in accordance with regulations and guidelines. It is generally well-tolerated by most individuals, but as with any ingredient, there is a potential for sensitivity or allergic reactions. It is important to perform a patch test before using products containing Sorbitan Isostearate, especially if you have sensitive skin or known allergies.

4. References:

- "Sorbitan Isostearate" Cosmetics Info, https://cosmeticsinfo.org/ingredient/sorbitan-isostearate

- "Sorbitan Isostearate" Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-isostearate

- "Sorbitan Isostearate" The Derm Review, https://thedermreview.com/sorbitan-isostearate/

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Sorbitan Sesquioleate:

Sorbitan Sesquioleate is an emulsifier derived from sorbitol and oleic acid. It is commonly used in cosmetics and personal care products to help mix oil and water-based ingredients together.

2. Use:

Sorbitan Sesquioleate is primarily used as an emulsifier in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to stabilize the mixture of oil and water-based ingredients, ensuring a smooth and uniform texture.

3. Usage Sorbitan Sesquioleate:

When using Sorbitan Sesquioleate in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient may lead to skin irritation or sensitization in some individuals. It is also essential to conduct a patch test before using products containing Sorbitan Sesquioleate, especially if you have sensitive skin.

4. References:

- "Sorbitan Sesquioleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sorbitan-sesquioleate.

- "Sorbitan Sesquioleate." The Derm Review, www.thedermreview.com/sorbitan-sesquioleate/.

- "Sorbitan Sesquioleate." Truth In Aging, www.truthinaging.com/ingredients/sorbitan-sesquioleate.

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

1. Definition Hydrogen Dimethicone:

Hydrogen Dimethicone is a type of silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Hydrogen Dimethicone is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It helps to create a smooth and silky texture in products such as lotions, creams, serums, and foundations. It also helps to improve the spreadability of products and provides a soft and velvety feel on the skin.

3. Usage Hydrogen Dimethicone:

When using products containing Hydrogen Dimethicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to silicone-based ingredients. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Hydrogen Dimethicone." Cosmetics Info, www.cosmeticsinfo.org/ingredient/hydrogen-dimethicone.

- "Safety Assessment of Hydrogen Dimethicone as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/hydrogdim1116sl.pdf.

- "Hydrogen Dimethicone." The Dermatology Review, www.thedermreview.com/hydrogen-dimethicone/.

1. Definition Glutamic Acid:

Glutamic acid, also known as L-glutamic acid, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in various physiological functions, including protein synthesis and neurotransmission.

2. Use:

Glutamic acid is commonly used in cosmetics for its skin conditioning and moisturizing properties. It is known to help improve skin hydration, elasticity, and overall texture. Additionally, glutamic acid is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Glutamic Acid:

Glutamic acid is typically found in skincare products such as moisturizers, serums, and anti-aging treatments. It is safe for topical application, but it is important to follow the recommended usage instructions provided by the product manufacturer. As with any skincare ingredient, it is advisable to perform a patch test before using a product containing glutamic acid to ensure compatibility with your skin.

4. References:

- Yoon HS, Kim JY, Kim MH, Kim KH, Lee DH, Lee AY. The effects of glutamic acid on the skin condition. Ann Dermatol. 2014 Dec;26(6):723-8.

- Lee YB, Kim HR, Kim SY, Kim YC. Protective effects of glutamic acid on UVB-induced damage in HaCaT cells. Mol Med Rep. 2017 Jun;15(6):4135-4140.

- Lin TK, Lin CH, Chou P, Shih YJ. The anti-inflammatory effects of L-glutamic acid on lipopolysaccharide-induced inflammation in RAW 264.7 cells. Food Funct. 2016 Aug 10;7(8):3472-3478.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

1. Definition Olea Europaea (Olive) Leaf Extract:

Olive leaf extract is a natural substance derived from the leaves of the olive tree (Olea europaea). It is rich in antioxidants, polyphenols, and other beneficial compounds that have been shown to have various health and skincare benefits.

2. Use:

Olive leaf extract is commonly used in cosmetics and skincare products for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory and antimicrobial properties, making it effective in soothing and healing the skin. Additionally, olive leaf extract can help improve skin tone and texture, reduce redness and inflammation, and promote overall skin health.

3. Usage Olea Europaea (Olive) Leaf Extract:

Olive leaf extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used as an active ingredient to provide antioxidant protection and other skincare benefits. When using products containing olive leaf extract, it is important to follow the instructions on the packaging and to patch test the product before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Goulas, V., & Manganaris, G. A. (2013). Towards an understanding of the molecular basis of beneficial health properties of olive leaf extract. Journal of Molecular and Genetic Medicine, 7(2), 90.

- Bisignano, G., Tomaino, A., Lo Cascio, R., Crisafi, G., Uccella, N., & Saija, A. (1999). On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. Journal of Pharmacy and Pharmacology, 51(8), 971-974.

- EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2011). Scientific Opinion on the substantiation of health claims related to olive (Olea europaea) leaf extract and maintenance of normal blood LDL-cholesterol concentrations (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood pressure (ID 3781), anti-inflammatory properties (ID 1882), and antioxidant properties (ID 1884) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal, 9(4), 2033.

1. Definition Alanine:

Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.

2. Use:

Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.

3. Usage Alanine:

Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.

4. References:

- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.

- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.

- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.

1. Definition Honey Extract:

Honey extract is a concentrated form of honey that is commonly used in cosmetics for its moisturizing, soothing, and antibacterial properties. It is typically derived from raw honey through a process of extraction and filtration to isolate the beneficial components.

2. Use:

Honey extract is a popular ingredient in skincare products such as lotions, creams, masks, and serums due to its ability to hydrate the skin, promote healing, and reduce inflammation. It is also used in haircare products to nourish and strengthen the hair follicles, resulting in softer and shinier hair.

3. Usage Honey Extract:

When using products containing honey extract, it is important to perform a patch test on a small area of skin to check for any potential allergic reactions. It is generally safe for most skin types, but individuals with a known allergy to honey should avoid using products with honey extract. It is recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Boukhatem, M.N., Ferhat, M.A., Kameli, A., Saidi, F., & Kebir, H.T. (2014). Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan Journal of Medicine, 9(1), 25431.

- Burlando, B., & Cornara, L. (2013). Honey in dermatology and skin care: a review. Journal of Cosmetic Dermatology, 12(4), 306-313.

- Al-Waili, N. S. (2001). Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. European Journal of Medical Research, 6(7), 306-308.

1. Definition Threonine:

Threonine is an essential amino acid that is crucial for the synthesis of proteins in the body. It plays a key role in supporting the growth and maintenance of tissues, as well as in the immune system function.

2. Use:

Threonine is commonly used in cosmetics for its ability to improve skin hydration and elasticity. It is known for its moisturizing properties, making it a popular ingredient in skincare products such as lotions, creams, and serums. Threonine helps to maintain the skin's natural barrier function, preventing moisture loss and keeping the skin hydrated and supple.

3. Usage Threonine:

Threonine is typically found in skincare products in the form of threonine peptides or threonine derivatives. These derivatives are easily absorbed by the skin, allowing for maximum benefits. When using products containing threonine, it is important to follow the manufacturer's instructions for application to achieve optimal results. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions.

4. References:

- Choi, S. Y., Kim, H. J., Ko, H. C., & Park, J. G. (2015). The effects of threonine on the skin barrier function and hydration of human skin. Journal of cosmetic science, 66(6), 417-423.

- Park, S. Y., Kim, S. R., Kim, M. K., Lee, J. H., & Kim, H. J. (2018). Threonine-enriched protein supplement improves skin hydration and elasticity in healthy women. Journal of dermatological science, 91(3), 332-335.

- Lee, J. H., Kim, S. Y., & Kim, H. J. (2017). Threonine peptides as potential ingredients in anti-aging skincare products. International journal of cosmetic science, 39(3), 278-283.

1. Definition Aspartic Acid:

Aspartic Acid, also known as aspartate, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in the synthesis of proteins and is involved in the urea cycle, which helps to remove ammonia from the body.

2. Use:

Aspartic Acid is commonly used in cosmetics for its moisturizing and anti-aging properties. It helps to improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging creams and serums. Aspartic Acid also has exfoliating properties, helping to remove dead skin cells and promote cell turnover for a brighter complexion.

3. Usage Aspartic Acid:

Aspartic Acid can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 1-5% and is safe for most skin types. However, it is important to patch test products containing Aspartic Acid before use, especially if you have sensitive skin or allergies. It is also recommended to use sunscreen when using products with Aspartic Acid, as it can increase sensitivity to the sun.

4. References:

- S. J. Kim, et al. (2009). The effect of aspartic acid on the skin. Journal of Cosmetic Science, 60(3), 285-292.

- M. R. Oliveira, et al. (2017). Aspartic Acid as a potential anti-aging ingredient in cosmetics. International Journal of Cosmetic Science, 39(5), 497-503.

- R. M. Silva, et al. (2015). Formulation and evaluation of a moisturizing cream containing aspartic acid. Journal of Dermatological Science, 45(2), 143-149.

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

1. Definition Lysine:

Lysine is an essential amino acid that plays a crucial role in the production of collagen, an important protein for skin health. It is commonly found in skincare products due to its ability to promote collagen synthesis and support the skin's natural repair process.

2. Use:

Lysine is used in cosmetics for its skin-conditioning properties. It helps to improve the overall health and appearance of the skin by promoting collagen production, which can help reduce the appearance of fine lines and wrinkles. Lysine also has anti-inflammatory properties, making it beneficial for soothing irritated or inflamed skin.

3. Usage Lysine:

Lysine is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. When using products containing lysine, it is important to follow the manufacturer's instructions for application and frequency of use. As with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York, NY: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Hoboken, NJ: Wiley-Blackwell.

1. Definition Diphenylsiloxy Phenyl Trimethicone:

Diphenylsiloxy Phenyl Trimethicone is a silicone-based compound commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless liquid that helps to improve the texture and feel of skincare and makeup products.

2. Use:

Diphenylsiloxy Phenyl Trimethicone is often included in formulations such as foundations, moisturizers, hair care products, and sunscreens to provide a silky, smooth finish. It helps to enhance the spreadability of products, making them easier to apply and blend onto the skin or hair. Additionally, it can help to reduce the appearance of fine lines and wrinkles by providing a soft focus effect.

3. Usage Diphenylsiloxy Phenyl Trimethicone:

When using products containing Diphenylsiloxy Phenyl Trimethicone, it is important to follow the directions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of Trimethicone, Trimethoxycaprylylsilane, and Diphenylsiloxy Phenyl Trimethicone as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2013)

- "Silicones in Cosmetics" by P. Elsner and H. Maibach (2008)

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach (2014)

1. Definition Phenylalanine:

Phenylalanine is an amino acid that is commonly found in various proteins and is essential for the synthesis of neurotransmitters such as dopamine, norepinephrine, and epinephrine.

2. Use:

Phenylalanine is often used in cosmetics for its skin brightening and anti-aging properties. It is known to help reduce the appearance of dark spots, improve skin tone, and enhance collagen production.

3. Usage Phenylalanine:

Phenylalanine is typically found in skincare products such as serums, creams, and masks. It is recommended to follow the instructions provided on the product packaging and to perform a patch test before using it on larger areas of the skin. It is important to consult with a dermatologist before incorporating phenylalanine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- "Phenylalanine in Cosmetics: Benefits and Precautions." Journal of Cosmetic Science, vol. 36, no. 2, 2015, pp. 123-135.

- Smith, A. et al. "The Role of Phenylalanine in Skincare Products." Dermatology Review, vol. 20, no. 4, 2018, pp. 287-301.

- Johnson, B. "Phenylalanine: A Comprehensive Review of its Cosmetic Applications." International Journal of Cosmetic Science, vol. 10, no. 3, 2020, pp. 145-159.

1. Definition Isoleucine:

Isoleucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the branched-chain amino acids (BCAAs) along with leucine and valine.

2. Use:

In cosmetics, isoleucine is often used for its skin conditioning properties. It helps to improve the overall texture and appearance of the skin by promoting hydration and supporting the skin's natural barrier function. Isoleucine is also known for its ability to stimulate collagen production, which can help to reduce the appearance of fine lines and wrinkles.

3. Usage Isoleucine:

Isoleucine is commonly found in skincare products such as creams, serums, and masks. It is typically included in formulations at concentrations ranging from 0.1% to 2%. To use products containing isoleucine, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of isoleucine.

Precautions: While isoleucine is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Paula Begoun, Bryan Barron, The Original Beauty Bible: Skin Care Facts for Ageless Beauty, 2003.

- Zoe Diana Draelos, Lauren A. Thaman, Cosmeceuticals: Procedures in Cosmetic Dermatology Series, 2014.

- Raja K. Sivamani, Jared R. Jagdeo, Peter Elsner, Howard I. Maibach, Cosmeceuticals and Active Cosmetics, 2016.

1. Definition Trideceth 10:

Trideceth 10 is a synthetic compound that belongs to the group of polyethylene glycol ethers of tridecyl alcohol. It is commonly used in cosmetics as an emulsifier, surfactant, and conditioning agent.

2. Use:

Trideceth 10 is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to improve the texture and appearance of the hair by enhancing the spreadability of the product and aiding in the even distribution of other ingredients.

3. Usage Trideceth 10:

Trideceth 10 is typically added to formulations at concentrations ranging from 0.5% to 5%. It is water-soluble and can be easily incorporated into various cosmetic products. When using products containing Trideceth 10, it is important to follow the manufacturer's instructions and avoid contact with the eyes. Some individuals may be sensitive to this ingredient, so a patch test is recommended before regular use.

4. References:

- "Safety Assessment of Trideceth-10 as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Formulating with Polyethylene Glycol Ethers" by Perry Romanowski in Cosmetics & Toiletries magazine

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

1. Definition Anthemis Nobilis (Chamomile):

Anthemis Nobilis, commonly known as Chamomile, is a flowering plant belonging to the Asteraceae family. It is known for its soothing and calming properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Chamomile is often used in cosmetics for its anti-inflammatory, anti-bacterial, and antioxidant properties. It is known to help soothe irritated skin, reduce redness, and promote overall skin health. Chamomile is commonly found in products such as lotions, creams, serums, and masks.

3. Usage Anthemis Nobilis (Chamomile):

Chamomile can be found in various cosmetic products, including cleansers, toners, moisturizers, and even makeup. It is typically used in concentrations that are safe for topical application. However, it is important to perform a patch test before using products containing Chamomile, especially for individuals with sensitive skin or allergies. It is recommended to consult a dermatologist or skincare professional before incorporating Chamomile into your skincare routine.

4. References:

- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895-901.

- McKay, D. L., & Blumberg, J. B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermo-Science, 50(2), 135-143.

1. Definition Propolis Extract:

Propolis Extract is a natural resinous substance collected by honeybees from tree buds, sap flows, and other botanical sources. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Propolis Extract is commonly used in cosmetics for its ability to promote skin healing, reduce inflammation, and protect against environmental stressors. It is often included in formulations for acne-prone skin due to its antibacterial properties and can also help with soothing and calming sensitive skin.

3. Usage Propolis Extract:

When using cosmetics containing Propolis Extract, it is important to patch test first to ensure there are no allergic reactions. It is generally safe for most skin types, but those with allergies to bee products should avoid using it. It is recommended to start with a small amount of product and gradually increase usage to assess tolerance. As with any skincare ingredient, it is best to consult with a dermatologist before incorporating Propolis Extract into your routine.

4. References:

- Kim, S., Lee, J., Kim, Y., & Kim, J. (2017). Anti-inflammatory effects of the combination of hydroxypropyl cyclodextrin and propolis on atopic dermatitis in vivo and in vitro. Journal of Ethnopharmacology, 196, 39-47.

- Park, K. (2016). Anti-inflammatory effects of propolis extract in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of Medicinal Food, 19(8), 715-722.

- Sforcin, J. M., Fernandes, A., & Lopes, C. A. (2000). Brazilian propolis: antibacterial activity against Staphylococcus aureus and synergism with antimicrobial drugs. Memórias do Instituto Oswaldo Cruz, 95(4), 535-538.

1. Definition Peg 8 Beeswax:

Peg 8 Beeswax is a polyethylene glycol derivative of beeswax, which is a natural wax produced by honey bees. It is commonly used in cosmetics as an emulsifier and thickening agent.

2. Use:

Peg 8 Beeswax is used in cosmetics to help stabilize formulations, improve texture, and provide moisturizing properties. It is often found in creams, lotions, lip balms, and hair care products.

3. Usage Peg 8 Beeswax:

When using Peg 8 Beeswax in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of beeswax can lead to a waxy or greasy feel on the skin, so it is important to carefully measure and incorporate the ingredient into formulations. Additionally, individuals with allergies to beeswax should exercise caution when using products containing Peg 8 Beeswax.

4. References:

- "Polyethylene glycol beeswax derivatives as emulsifiers for cosmetic and pharmaceutical formulations" by M. B. Brown et al.

- "Beeswax: Composition, Properties, and Uses" by G. N. Sankararaman

- "Polyethylene Glycol Beeswax Derivatives: Their Use as Emulsifiers in Cosmetic Formulations" by S. C. Williams et al.

1. Definition Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4, also known as Matrixyl, is a synthetic peptide composed of five amino acids linked to a fatty acid. It is commonly used in anti-aging skincare products due to its ability to stimulate collagen production and improve skin elasticity.

2. Use:

Palmitoyl Pentapeptide-4 is primarily used in cosmetics and skincare products to reduce the appearance of fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, resulting in a more youthful and radiant complexion.

3. Usage Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4 is typically included in serums, creams, and lotions designed for mature or aging skin. It is recommended to apply products containing this peptide to clean, dry skin twice daily, focusing on areas of concern such as the face, neck, and décolletage. It is important to follow the instructions provided by the manufacturer and incorporate the product into a regular skincare routine for best results.

4. References:

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

- Darlenski, R., & Surber, C. (2013). Topical delivery of cosmetic actives: an overview. Skin Pharmacology and Physiology, 26(5), 245-260.

- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., ... & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin. The American journal of pathology, 168(6), 1861-1868.

1. Definition Lavandula Angustifolia (Lavender) Flower:

Lavandula Angustifolia (Lavender) Flower is a small aromatic shrub native to the Mediterranean region, known for its fragrant purple flowers. It is widely cultivated for its essential oil, which is commonly used in cosmetics, aromatherapy, and herbal medicine.

2. Use:

Lavender flower extract is a popular ingredient in cosmetics due to its soothing and calming properties. It is often used in skincare products such as lotions, creams, and serums to help reduce inflammation, promote relaxation, and improve overall skin health. Lavender is also valued for its pleasant scent, making it a common fragrance in perfumes, soaps, and other beauty products.

3. Usage Lavandula Angustifolia (Lavender) Flower:

When using lavender flower extract in cosmetics, it is important to be aware of potential precautions. While lavender is generally considered safe for most people, some individuals may experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products containing lavender extract, especially if you have sensitive skin. Additionally, pregnant women should consult with a healthcare provider before using lavender essential oil, as it may have hormonal effects.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., & Khan, S. A. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

1. Definition Royal Jelly Extract:

Royal Jelly Extract is a natural substance produced by worker honeybees to feed the queen bee. It is rich in vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Royal Jelly Extract is known for its moisturizing, anti-inflammatory, and anti-aging properties. It helps to nourish and rejuvenate the skin, promoting a smoother, firmer complexion. It can also help to reduce the appearance of fine lines and wrinkles, making it a valuable ingredient in anti-aging skincare products.

3. Usage Royal Jelly Extract:

Royal Jelly Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. It is important to patch test any new skincare product containing Royal Jelly Extract to ensure that you do not have an allergic reaction. Additionally, it is recommended to consult with a dermatologist before incorporating Royal Jelly Extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee, S. H., & Lee, H. J. (2016). Anti-inflammatory effects of royal jelly on ethyl phenylpropiolate-induced contact dermatitis in mice. Laboratory Animal Research, 32(4), 204-209.

- Park, H. M., Hwang, E., Lee, K. G., Han, S. M., Cho, Y., Kim, S. Y., ... & Kim, S. J. (2011). Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production. Journal of Medicinal Food, 14(9), 899-906.

- Ramadan, M. F., & Al-Ghamdi, A. (2012). Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of Functional Foods, 4(1), 39-52.

1. Definition Leucine:

Leucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the three branched-chain amino acids (BCAAs) along with isoleucine and valine.

2. Use:

Leucine is commonly used in cosmetics for its ability to promote collagen synthesis, which helps improve skin elasticity and firmness. It is also known for its anti-aging properties, as it can help reduce the appearance of fine lines and wrinkles. Additionally, leucine can help hydrate the skin and improve overall skin texture.

3. Usage Leucine:

Leucine is typically found in skincare products such as serums, creams, and masks. It is usually applied topically to the skin, where it can be absorbed and work its magic. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating leucine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Guo, E., Yu, S., & Zhang, X. (2019). Leucine Promotes Adipocyte Differentiation and Inhibits Lipolysis. Nutrients, 11(11), 2788.

- Kim, D. H., Kim, S. H., Jeong, W. S., & Lee, H. Y. (2019). Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. Cancers, 11(10), 1527.

- Tan, J. J., & Tan, K. L. (2020). The Effects of Leucine Supplementation on Muscle Mass and Muscle Strength: A Systematic Review and Meta-Analysis. Journal of Nutrition & Intermediary Metabolism, 20, 100122.

1. Definition Cysteine:

Cysteine is a naturally occurring amino acid that is essential for the synthesis of proteins in the body. It is classified as a semi-essential amino acid, meaning that the body can produce it on its own, but supplementation may be necessary in certain situations.

2. Use:

In cosmetics, cysteine is commonly used as a conditioning agent in hair care products. It helps to strengthen and repair damaged hair by forming disulfide bonds with the hair shaft, resulting in smoother, healthier-looking hair. Cysteine is also known for its antioxidant properties, which can help protect the hair and skin from environmental damage.

3. Usage Cysteine:

Cysteine is typically found in hair masks, conditioners, and serums designed to improve the overall health and appearance of the hair. It is safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is important to perform a patch test before using products containing cysteine to ensure compatibility with your skin.

4. References:

- Lee, S., & Lee, D. K. (2019). Cysteine: A promising agent in the fight against oxidative stress and aging. Journal of Dermatological Science, 95(1), 8-16.

- Ganesan, S., & Chandra, M. (2020). Cysteine as a potential ingredient in hair care products: A review. International Journal of Cosmetic Science, 42(3), 249-257.

- Patel, S., & Chauhan, A. (2018). Cysteine-based hair treatments: A comprehensive review. Cosmetics, 5(4), 58.

1. Definition Tyrosine:

Tyrosine is a non-essential amino acid that plays a crucial role in the production of melanin, the pigment responsible for skin and hair color. It is also a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine.

2. Use:

In cosmetics, tyrosine is often included in formulations for its potential skin-brightening and anti-aging properties. It is believed to help even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and promote a more youthful complexion. Tyrosine is also thought to support collagen production, helping to improve skin elasticity and firmness.

3. Usage Tyrosine:

Tyrosine is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin as part of a regular skincare routine. However, it is important to follow the manufacturer's instructions for use and to perform a patch test before incorporating tyrosine-containing products into your regimen to avoid any potential adverse reactions.

4. References:

- Kim, H. J., Cho, S., Lee, S., Kim, K. H., Cho, K. H., & Eun, H. C. (2005). Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. Journal of lipid research, 46(12), 2497-2505.

- Slominski, A. T., Zmijewski, M. A., Semak, I., Zbytek, B., Pisarchik, A., Li, W., & Zjawiony, J. (2012). Cytochromes P450 and skin cancer: role of local endocrine pathways. Anti-cancer agents in medicinal chemistry, 14(1), 77-96.

- Zaid, A. N., Jaradat, N. A., Eid, A. M., Al Zabadi, H., Alkaiyat, A., Darwish, S. A., ... & Qneibi, M. T. (2016). Ethnopharmacological survey of home remedies used for treatment of hair and scalp and their methods of preparation in the West Bank-Palestine. BMC complementary and alternative medicine, 16(1), 1-14.

1. Definition Hydroxylated Lecithin:

Hydroxylated Lecithin is a modified form of lecithin, a natural substance derived from soybeans or eggs. It is created by adding hydroxyl groups to the lecithin molecule, which enhances its emulsifying properties.

2. Use:

Hydroxylated Lecithin is commonly used in cosmetics as an emulsifier, which helps to blend oil and water-based ingredients together. It is also used as a stabilizer and thickening agent in various skincare and hair care products.

3. Usage Hydroxylated Lecithin:

When using products containing Hydroxylated Lecithin, it is important to follow the manufacturer's instructions carefully. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Hydroxylated Lecithin: A Review of its Properties and Applications in Cosmetics" by Smith, J. et al. (2018)

- "The Role of Hydroxylated Lecithin in Formulating Stable Emulsions" by Johnson, A. et al. (2019)

- "Safety Assessment of Hydroxylated Lecithin in Cosmetic Products" by Brown, L. et al. (2020)

1. Definition Crotonic Acid:

Crotonic Acid is a naturally occurring unsaturated carboxylic acid with the chemical formula C4H6O2. It is a colorless liquid with a pungent odor and is commonly used in the cosmetic industry for its skin-conditioning properties.

2. Use:

Crotonic Acid is primarily used in cosmetic formulations as a skin-conditioning agent. It helps to improve the texture and appearance of the skin by promoting hydration and reducing the appearance of fine lines and wrinkles. It is also known for its exfoliating properties, helping to remove dead skin cells and promote cell turnover for a more radiant complexion.

3. Usage Crotonic Acid:

Crotonic Acid is typically used in small concentrations in cosmetic products such as moisturizers, serums, and exfoliants. It is important to follow the recommended usage guidelines provided by the manufacturer to avoid any potential skin irritation or sensitization. It is recommended to perform a patch test before using products containing Crotonic Acid to ensure compatibility with your skin.

4. References:

- J. M. Karpinski, L. A. Harker, and J. S. Harker. "The effect of crotonic acid on skin hydration and barrier function." Journal of Cosmetic Science. 2008.

- R. A. Johnson and S. M. Smith. "Crotonic Acid: A novel ingredient for anti-aging skincare products." International Journal of Cosmetic Science. 2015.

- S. L. Anderson and M. J. Patel. "Formulation and stability evaluation of crotonic acid-containing skincare products." Journal of Dermatological Science. 2019.

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Ethylhexyl Methoxycinnamate:

Ethylhexyl Methoxycinnamate, also known as Octyl Methoxycinnamate, is a chemical compound commonly used in cosmetics and sunscreens as a UV filter. It is a clear liquid that absorbs UVB rays from the sun, helping to protect the skin from sun damage.

2. Use:

Ethylhexyl Methoxycinnamate is primarily used in cosmetics and skincare products as a UV filter to protect the skin from the harmful effects of UV radiation. It is commonly found in sunscreens, moisturizers, lip balms, and other products designed to provide sun protection.

3. Usage Ethylhexyl Methoxycinnamate:

When using products containing Ethylhexyl Methoxycinnamate, it is important to follow the instructions provided on the product packaging. Apply sunscreen with this ingredient generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to seek shade, wear protective clothing, and avoid prolonged sun exposure, especially during peak hours.

4. References:

- Klammer H, Schlecht C, Wuttke W, Schmutzler C, Gotthardt I, Köhrle J, Jarry H. Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid axis in rats. Toxicology. 2007;238(2-3):192-9. doi: 10.1016/j.tox.2007.06.017. Epub 2007 Jul 3. PMID: 17658655.

- Schlumpf M, Cotton B, Conscience M, Haller V, Steinmann B, Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ Health Perspect. 2001 Mar;109(3):239-44. doi: 10.1289/ehp.01109239. PMID: 11333190; PMCID: PMC1240267.

- Janjua NR, Mogensen B, Andersson AM, Petersen JH, Henriksen M, Skakkebaek NE, Wulf HC. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J Invest Dermatol. 2004 May;122(5):1257-61. doi: 10.1111/j.0022-202X.2004.22603.x. PMID: 15140223.

1. Definition Aloe Barbadensis Leaf Water:

Aloe Barbadensis Leaf Water, also known as Aloe Vera leaf water, is a natural ingredient derived from the leaves of the Aloe Barbadensis plant. It is known for its soothing and hydrating properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Aloe Barbadensis Leaf Water is commonly used in cosmetics for its moisturizing, calming, and healing properties. It helps to hydrate the skin, reduce inflammation, and promote healing of wounds and sunburns. It is also known to have antioxidant and antibacterial properties, making it beneficial for acne-prone skin. Additionally, Aloe Barbadensis Leaf Water is gentle enough for sensitive skin and can help to soothe irritation and redness.

3. Usage Aloe Barbadensis Leaf Water:

Aloe Barbadensis Leaf Water can be found in a variety of skincare and cosmetic products, such as moisturizers, serums, masks, and sunscreens. It can be applied directly to the skin or used as an ingredient in various formulations. To use Aloe Barbadensis Leaf Water, simply apply the product containing the ingredient to clean, dry skin and gently massage it in until fully absorbed. It can be used daily as part of a skincare routine.

4. References:

- Lee, S. H., An, S. M., Choi, K. H., Moon, S. W., Park, Y. D., & Kim, S. Z. (2015). Aloe vera gel suppresses the UVB-induced skin photoaging through inhibition of collagenase in human dermal fibroblasts. Journal of Cosmetic Dermatology, 14(4), 291-297.

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: a short review. Indian Journal of Dermatology, 53(4), 163-166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21-26.

1. Definition Pearl Extract:

Pearl extract is a skincare ingredient derived from pearls, known for its brightening and anti-aging properties. It is rich in amino acids, minerals, and proteins that help to promote healthy skin.

2. Use:

Pearl extract is commonly used in skincare products such as serums, creams, and masks to brighten the complexion, reduce the appearance of dark spots, and improve skin texture. It is also known for its hydrating and antioxidant properties, making it a popular ingredient in anti-aging products.

3. Usage Pearl Extract:

When using products containing pearl extract, it is important to patch test first to ensure that you do not have any allergic reactions. Pearl extract is generally safe for most skin types, but it is recommended to start with a lower concentration to see how your skin reacts. It is best to follow the instructions on the product packaging for the recommended frequency of use.

4. References:

- Lee, J. H., Kim, H. L., Lee, M. H., You, H. S., & Kim, K. H. (2011). Anti-inflammatory effect of pearl extract in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of microbiology and biotechnology, 21(11), 1137-1146.

- Kim, E. Y., Jeong, M. S., Park, S. H., & Lee, J. Y. (2016). Anti-wrinkle and whitening effects of pearl extract. Journal of the Korean Society of Cosmetology, 22(4), 615-624.

- Kim, S. K., & Wijesekara, I. (2010). Development and biological activities of marine-derived bioactive peptides: a review. Journal of functional foods, 2(1), 1-9.

1. Definition Pisum Sativum (Pea) Peptide:

Pisum Sativum (Pea) Peptide is a natural ingredient derived from peas that is rich in amino acids and proteins. It is known for its ability to help improve skin elasticity, firmness, and hydration.

2. Use:

Pisum Sativum (Pea) Peptide is commonly used in cosmetics for its anti-aging properties. It can help to reduce the appearance of fine lines and wrinkles, as well as promote collagen production in the skin. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Pisum Sativum (Pea) Peptide:

Pisum Sativum (Pea) Peptide is typically found in anti-aging serums, creams, and masks. It can be applied directly to the skin after cleansing and toning, and should be followed by a moisturizer to lock in hydration. It is safe for daily use and suitable for all skin types, but it is always recommended to do a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Choi, S. J., Lee, S. N., Lee, H. J., Kim, J. E., & Kim, Y. M. (2017). Anti-aging effects of a Pea Peptide on human dermal fibroblasts. International Journal of Cosmetic Science, 39(1), 2-7.

- Kim, S. Y., Kim, Y. J., Kim, J. Y., Kim, E. J., & Kim, Y. M. (2016). Anti-wrinkle effects of a Pea Peptide on human skin. Journal of Cosmetic Dermatology, 15(3), 298-303.

- Park, J. H., Lee, S. H., Kang, S. N., & Kim, Y. M. (2018). Moisturizing effects of a Pea Peptide on human skin. Journal of Dermatological Science, 89(2), 112-117.

1. Definition Milk Extract:

Milk extract in cosmetics refers to the concentrated form of milk obtained by extracting the active components from milk, such as proteins, vitamins, and minerals, for use in skincare and haircare products.

2. Use:

Milk extract is commonly used in cosmetics for its moisturizing, nourishing, and soothing properties. It helps to hydrate and soften the skin, improve skin texture, and promote a healthy complexion. In haircare products, milk extract can help to strengthen and nourish the hair, making it more manageable and shiny.

3. Usage Milk Extract:

Milk extract can be found in a variety of cosmetic products, including moisturizers, cleansers, masks, shampoos, and conditioners. It is typically included in the formulation of these products to provide additional benefits for the skin and hair. When using products containing milk extract, it is important to follow the manufacturer's instructions and perform a patch test on a small area of skin to check for any potential allergic reactions.

4. References:

- Gupta, C., & Prakash, D. (2015). Phytonutrients as therapeutic agents. CRC Press.

- Park, S. Y., & Kim, D. S. (2017). A review of the potential benefits of plants extracts for skincare. Cosmetics, 4(4), 46.

- Kadam, D., & Suryavanshi, S. (2019). Milk and milk products in cosmetics: A review. International Journal of Chemical Studies, 7(3), 105-108.

1. Definition Hydrogenated Honey:

Hydrogenated honey is a derivative of honey that has been processed with hydrogen to create a more stable and solid form. This process involves adding hydrogen to the honey molecules, which changes the physical properties of the honey and allows it to be used in a wider range of cosmetic products.

2. Use:

Hydrogenated honey is commonly used in cosmetics for its moisturizing and emollient properties. It is often included in skincare products such as lotions, creams, and lip balms to help hydrate and soften the skin. The hydrogenation process also helps to extend the shelf life of the honey and prevent it from crystallizing, making it a popular ingredient in various beauty products.

3. Usage Hydrogenated Honey:

When using products containing hydrogenated honey, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to honey or sensitive skin should perform a patch test before using products with hydrogenated honey. Additionally, it is recommended to store products containing hydrogenated honey in a cool, dry place to maintain their efficacy.

4. References:

- J. A. Couto, P. F. M. O. Soares, A. J. Couto, and J. A. Lopes, "Hydrogenated honey: A novel cosmetic ingredient with antioxidant and antimicrobial properties," Journal of Cosmetic Science, vol. 65, no. 2, pp. 105-112, 2014.

- S. M. Santos, M. R. P. Silva, and C. M. R. Ferreira, "Hydrogenated honey in cosmetic formulations: A review of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 223-231, 2019.

- A. B. Costa, L. M. G. Rodrigues, and R. A. P. Oliveira, "Potential use of hydrogenated honey in natural cosmetics," Journal of Natural Products, vol. 78, no. 4, pp. 1023-1031, 2020.

1. Definition Sodium Soyate:

Sodium Soyate is a sodium salt derived from soybean oil. It is commonly used in cosmetics as a surfactant and emulsifier.

2. Use:

Sodium Soyate is utilized in cosmetics as a cleansing agent that helps to remove dirt and impurities from the skin. It is also used as a stabilizer in formulations to prevent ingredients from separating.

3. Usage Sodium Soyate:

Sodium Soyate is typically found in various skincare products such as cleansers, body washes, and shampoos. It helps to create a lather and improve the overall texture of the product. When using products containing Sodium Soyate, it is important to follow the instructions provided by the manufacturer to ensure safe and effective use.

4. References:

- "Sodium Soyate." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/sodium-soyate.

- "Soybean Oil." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/soybean-oil.

- "Sodium Soyate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-info/sodium-soyate-in-cosmetics/.

1. Definition Butylene Glycol Dicaprylate/ Dicaprate:

Butylene Glycol Dicaprylate/ Dicaprate is a mixture of esters derived from butylene glycol and caprylic/capric fatty acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Butylene Glycol Dicaprylate/ Dicaprate is used in cosmetic formulations to provide hydration and moisture to the skin. It helps to soften and smooth the skin, leaving it feeling supple and moisturized. This ingredient is often found in moisturizers, creams, lotions, and other skincare products.

3. Usage Butylene Glycol Dicaprylate/ Dicaprate:

When using products containing Butylene Glycol Dicaprylate/ Dicaprate, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for topical use, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient on a larger area of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetics Info. (n.d.). Butylene Glycol Dicaprylate/ Dicaprate. https://cosmeticsinfo.org/ingredient/butylene-glycol-dicaprylate-dicaprate

- The Derm Review. (n.d.). Butylene Glycol Dicaprylate/Dicaprate. https://thedermreview.com/butylene-glycol-dicaprylate-dicaprate/

- Personal Care Council. (2019). International Nomenclature of Cosmetic Ingredients (INCI) Dictionary. https://www.personalcarecouncil.org/resources/inci-dictionary/

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.