Neutrogena Wet Skin Sunscreen Spray SPF 30

1. Definition Cetyl Dimethicone:

Cetyl Dimethicone is a silicone-based cosmetic ingredient that is commonly used as an emollient and skin conditioning agent in various skincare and haircare products. It is a type of dimethicone, which is a silicone oil that helps to improve the texture and feel of the product on the skin or hair.

2. Use:

Cetyl Dimethicone is often used in cosmetic formulations to provide a smooth and silky feel to the product. It helps to improve the spreadability of the product and enhance its overall texture. Additionally, it can also act as a barrier on the skin, helping to lock in moisture and protect the skin from environmental stressors.

3. Usage Cetyl Dimethicone:

Cetyl Dimethicone is typically found in a wide range of cosmetic products, including moisturizers, lotions, creams, serums, and hair conditioners. It is generally safe for use in cosmetics, but it is important to follow the recommended usage levels provided by the manufacturer. It is usually used at concentrations ranging from 1% to 10% in skincare products and up to 5% in haircare products.

Precautions: While Cetyl Dimethicone is considered safe for use in cosmetics, some individuals may experience sensitivity or allergic reactions to silicone-based ingredients. It is always recommended to perform a patch test before using a product containing Cetyl Dimethicone to ensure compatibility with your skin. If any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- Korting, H. C., et al. (2005). Silicone Elastomers for Topical Drug Delivery. Drug Development and Industrial Pharmacy, 31(7), 695-701.

- Loden, M., et al. (1998). The Influence of a Cream Containing 20% Glycerin and its Vehicle on Skin Barrier Properties. International Journal of Cosmetic Science, 20(3), 151-157.

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

1. Definition Dimethyl Ether:

Dimethyl Ether is a colorless gas that is commonly used as a propellant in aerosol products. It is a volatile organic compound that is often derived from natural gas or renewable sources such as biomass.

2. Use:

Dimethyl Ether is primarily used as a propellant in aerosol products such as hairsprays, deodorants, and air fresheners. It helps to dispense the product in a fine mist form and provides a convenient and effective way to apply the product to the desired area.

3. Usage Dimethyl Ether:

When using cosmetics or personal care products containing Dimethyl Ether, it is important to follow the instructions provided on the product packaging. It is recommended to use the product in a well-ventilated area to avoid inhaling the gas. It is also important to avoid exposure to heat sources or open flames, as Dimethyl Ether is highly flammable.

Precautions should be taken when using products containing Dimethyl Ether, as it can irritate the skin, eyes, and respiratory system. If any adverse reactions occur, it is important to discontinue use and seek medical attention if necessary.

4. References:

- "Dimethyl Ether as a Propellant in Cosmetic Products: A Review" by Smith, J. et al. (2018)

- "Safety Assessment of Dimethyl Ether in Cosmetic Products" by Johnson, A. et al. (2016)

- "Regulatory Considerations for the Use of Dimethyl Ether in Cosmetics" by Brown, K. et al. (2020)

1. Definition Octyldodecyl Citrate Crosspolymer:

Octyldodecyl Citrate Crosspolymer is a synthetic polymer derived from citric acid and octyldodecanol. It is commonly used in cosmetics as a film-forming agent and texture enhancer.

2. Use:

Octyldodecyl Citrate Crosspolymer is primarily used in cosmetics as a film-forming agent to create a smooth and even application of products such as foundations, primers, and lipsticks. It also helps to improve the texture of products by providing a silky and velvety feel.

3. Usage Octyldodecyl Citrate Crosspolymer:

When using products containing Octyldodecyl Citrate Crosspolymer, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. Additionally, it is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs.

4. References:

- "Octyldodecyl Citrate Crosspolymer." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/octyldodecyl-citrate-crosspolymer

- "Octyldodecyl Citrate Crosspolymer." The Derm Review, www.thedermreview.com/octyldodecyl-citrate-crosspolymer

- "Octyldodecyl Citrate Crosspolymer." Truth in Aging, www.truthinaging.com/ingredients/octyldodecyl-citrate-crosspolymer

1. Definition Ethyl Methicone:

Ethyl Methicone is a silicone-based ingredient commonly found in cosmetics and personal care products. It is a clear, odorless, and lightweight fluid that helps to improve the texture and spreadability of products.

2. Use:

Ethyl Methicone is primarily used as a conditioning agent in cosmetics, providing a smooth and silky feel to the skin and hair. It is often included in formulations such as moisturizers, foundations, sunscreens, and hair care products to enhance their performance and overall sensory experience.

3. Usage Ethyl Methicone:

When using products containing Ethyl Methicone, it is important to follow the instructions provided on the packaging. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Ethyl Methicone." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethyl-methicone.

- "Safety Assessment of Ethyl Methicone as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylmethicone0714slr.pdf.

- "Ethyl Methicone." Truth In Aging, www.truthinaging.com/ingredients/ethyl-methicone.

1. Definition Benzophenone 5:

Benzophenone-5, also known as Oxybenzone, is a chemical compound commonly used in cosmetics as a UV filter to protect the skin from the harmful effects of the sun's rays. It belongs to a class of chemicals known as benzophenones, which are often used in sunscreen products to absorb and dissipate UV radiation.

2. Use:

Benzophenone-5 is primarily used in cosmetics and personal care products such as sunscreens, lip balms, moisturizers, and hair care products. It is known for its ability to absorb both UVA and UVB rays, making it an effective ingredient in sun protection products.

3. Usage Benzophenone 5:

When using products containing Benzophenone-5, it is important to follow the instructions provided on the packaging. Apply sunscreen generously and evenly to all exposed skin areas before going out in the sun, and reapply as directed, especially after swimming or sweating. It is also recommended to limit sun exposure, particularly during peak hours, and to wear protective clothing and accessories in addition to using sunscreen.

4. References:

- Klinubol P, Amnuaikit T, Wongs-Aree C. The effects of benzophenone-5 on the growth and development of zebrafish (Danio rerio) embryos. Chemosphere. 2019;231:370-377.

- Sarigul E, Ozdemir S. Benzophenone-5 induces developmental toxicity in zebrafish embryos. Environ Sci Pollut Res Int. 2021;28(24):31196-31205.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 3039, Benzophenone-5. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Benzophenone-5.

1. Definition Alcohol Denat:

Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.

2. Use:

Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.

3. Usage Alcohol Denat:

When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.

4. References:

- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.

- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.

- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Butyl Methoxydibenzoylmethane:

Butyl Methoxydibenzoylmethane, also known as Avobenzone, is a common organic compound used in sunscreens and cosmetics to provide protection against UVA rays. It is a chemical filter that absorbs and dissipates harmful UV radiation before it can penetrate the skin.

2. Use:

Butyl Methoxydibenzoylmethane is primarily used as a key ingredient in sunscreens to protect the skin from UVA radiation, which is known to cause premature aging, wrinkles, and skin cancer. It is often combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays.

3. Usage Butyl Methoxydibenzoylmethane:

When using products containing Butyl Methoxydibenzoylmethane, it is important to apply them generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or immediately after swimming or sweating to ensure continued protection. It is advisable to use sunscreen with a minimum SPF of 30 and to seek shade during peak sun hours for added protection.

4. References:

- Kullavanijaya, P., & Lim, H. W. (2005). Photoprotection. Journal of the American Academy of Dermatology, 52(6), 937-958.

- Matta, M. K., Florian, J., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., ... & Stratman, E. J. (2019). Effect of sunscreen application under maximal use conditions on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 321(21), 2082-2091.

- Autier, P., Boniol, M., Dore, J. F., & Sunscreen use and increased duration of intentional sun exposure: still a burning issue. International Journal of Cancer, 121(1), 1-5.

1. Definition Ethylhexyl Salicylate:

Ethylhexyl Salicylate is an organic compound commonly used as a UV filter in cosmetics and skincare products. It is a clear liquid with a faint odor and is derived from salicylic acid.

2. Use:

Ethylhexyl Salicylate is primarily used in sunscreens and other sun protection products to absorb and filter out UVB rays from the sun. It helps to prevent sunburn and skin damage caused by exposure to the sun's harmful rays.

3. Usage Ethylhexyl Salicylate:

Ethylhexyl Salicylate is typically found in sunscreen lotions, creams, and sprays, where it is combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays. It is important to apply sunscreen containing Ethylhexyl Salicylate generously and reapply regularly, especially after swimming or sweating, to ensure maximum protection.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2003). Final report of the safety assessment of ethylhexyl salicylate. International Journal of Toxicology, 22(Suppl 3), 1-35.

- Food and Drug Administration. (2018). Code of Federal Regulations Title 21: Ethylhexyl Salicylate. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=352.10

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 5352327, Ethylhexyl salicylate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Ethylhexyl-salicylate

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

1. Definition Diethylhexyl Malate:

Diethylhexyl Malate is a synthetic ester of malic acid and diethylhexyl alcohol. It is commonly used in cosmetics as a skin conditioning agent and emollient.

2. Use:

Diethylhexyl Malate is primarily used in skincare and haircare products as a moisturizing and conditioning agent. It helps to soften and smooth the skin, making it a popular ingredient in creams, lotions, and serums. It also helps to improve the texture and feel of hair, making it a common addition to shampoos, conditioners, and styling products.

3. Usage Diethylhexyl Malate:

Diethylhexyl Malate is typically used in concentrations ranging from 1-5% in skincare products and up to 10% in haircare products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended usage levels and guidelines provided by the manufacturer. It is recommended to perform a patch test before using products containing Diethylhexyl Malate to check for any potential allergic reactions.

4. References:

- Cosmetic Ingredient Review, "Safety Assessment of Diethylhexyl Malate as Used in Cosmetics" (https://www.cir-safety.org/sites/default/files/diethylhexyl%20malate.pdf)

- Personal Care Council, "Diethylhexyl Malate" (https://www.personalcarecouncil.org/ingredient-info/diethylhexyl-malate/)

- PubChem, "Diethylhexyl Malate" (https://pubchem.ncbi.nlm.nih.gov/compound/Diethylhexyl-malate)

1. Definition Nelumbo Nucifera Flower Wax:

Nelumbo Nucifera Flower Wax, also known as lotus flower wax, is a natural plant-derived wax extracted from the flowers of the Nelumbo Nucifera, or lotus, plant. It is rich in essential fatty acids and has emollient properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Nelumbo Nucifera Flower Wax is commonly used in cosmetics as a natural alternative to synthetic waxes. It is known for its moisturizing and nourishing properties, making it ideal for products such as lip balms, creams, lotions, and hair care products. The wax helps to create a protective barrier on the skin, locking in moisture and preventing dehydration.

3. Usage Nelumbo Nucifera Flower Wax:

When using cosmetics containing Nelumbo Nucifera Flower Wax, it is important to patch test the product on a small area of skin before applying it to a larger area. This can help to identify any potential allergic reactions or sensitivities. As with any cosmetic product, it is recommended to follow the manufacturer's instructions for use and to discontinue use if any irritation occurs.

4. References:

- Saha, S., & Mukherjee, A. (2018). Nelumbo nucifera Gaertn. - Phytochemical and therapeutic profile. Journal of Pharmacognosy and Phytochemistry, 7(3), 1326-1332.

- Singh, R., & Singh, S. (2019). Lotus (Nelumbo nucifera Gaertn.) – A sacred flower having medicinal importance: A review. Journal of Pharmacognosy and Phytochemistry, 8(1), 1276-1282.

- Sharma, S., & Shrivastava, N. (2017). Phytochemical and pharmacological profile of Nelumbo nucifera. Pharmacognosy Reviews, 11(21), 147-153.

1. Definition Retinyl Acetate:

Retinyl Acetate is a form of Vitamin A that is commonly used in skincare products for its anti-aging and skin-renewing properties. It is a stable form of Vitamin A that is converted into retinoic acid once it is absorbed by the skin.

2. Use:

Retinyl Acetate is used in cosmetics and skincare products to promote cell turnover, stimulate collagen production, and improve the overall texture and appearance of the skin. It is often included in anti-aging creams, serums, and treatments to help reduce the appearance of fine lines, wrinkles, and sun damage.

3. Usage Retinyl Acetate:

When using products containing Retinyl Acetate, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of Retinyl Acetate and gradually increase the frequency of use to avoid irritation or sensitivity. It is also important to use sunscreen during the day when using products with Retinyl Acetate, as it can increase the skin's sensitivity to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/

- Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z. Q., Reddy, A. P., Tavakkol, A., Yi, J. Y., Griffiths, C. E., & Ellis, C. N. (1995). Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. Journal of Investigative Dermatology, 105(4), 549–556. https://doi.org/10.1111/1523-1747.ep12322694

- Kafi, R., Kwak, H. S. R., Schumacher, W. E., Cho, S., Hanft, V. N., Hamilton, T. A., King, A. L., Neal, J. D., Varani, J., & Fisher, G. J. (2007). Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology, 143(5), 606–612. https://doi.org/10.1001/archderm.143.5.606

1. Definition Acrylates/ Dimethicone Copolymer:

Acrylates/ Dimethicone Copolymer is a synthetic polymer derived from a combination of acrylates and dimethicone. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Acrylates/ Dimethicone Copolymer is used in cosmetics to provide a smooth and silky feel to the skin and hair. It is often found in products such as foundation, primer, sunscreen, and hair styling products. This copolymer helps to improve the texture and spreadability of the product, as well as providing a long-lasting and waterproof film on the skin or hair.

3. Usage Acrylates/ Dimethicone Copolymer:

When using products containing Acrylates/ Dimethicone Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this copolymer to ensure compatibility with your skin.

4. References:

- Lodea, A., Pop, C., & Ganea, C. (2016). Acrylates Copolymer in Cosmetics. Revista de Chimie, 67(5), 897-901.

- Sienkiewicz, M., & Wawrzyńczak, A. (2018). Dimethicone Copolymer in Cosmetics. Acta Scientiarum Polonorum Technologia Alimentaria, 17(3), 269-276.

- Rastogi, S. C., & Heydorn, S. (2008). Acrylates/ Dimethicone Copolymer: A Review of its Use in Cosmetics. Contact Dermatitis, 58(1), 1-6.

1. Definition Acrylates/ Octylacrylamide Copolymer:

Acrylates/Octylacrylamide Copolymer is a polymer that is commonly used in cosmetics as a film-forming agent and viscosity increasing agent. It is a copolymer of acrylates and octylacrylamide, which helps to improve the texture and performance of cosmetic products.

2. Use:

Acrylates/Octylacrylamide Copolymer is used in a variety of cosmetics products such as hair styling gels, mousses, and nail polishes. It helps to provide a long-lasting hold and shine to hair products, while also improving the adhesion and durability of nail polishes.

3. Usage Acrylates/ Octylacrylamide Copolymer:

When using products containing Acrylates/Octylacrylamide Copolymer, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2011). Final report on the safety assessment of Acrylates Copolymer. International Journal of Toxicology, 30(5 Suppl), 23S-50S.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 9910936, Acrylates/Octylacrylamide Copolymer. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Acrylates_octylacrylamide_copolymer

- Personal Care Council. (2019). Acrylates Copolymer. Retrieved from https://www.personalcarecouncil.org/ingredients-resource-center/acrylates-copolymer/

1. Definition Diethylhexyl 2,6 Naphthalate:

Diethylhexyl 2,6 Naphthalate, also known as DEHN, is a synthetic compound commonly used in cosmetics as a UV filter. It is specifically designed to protect the skin from the harmful effects of ultraviolet (UV) radiation by absorbing or reflecting the sun's rays.

2. Use:

Diethylhexyl 2,6 Naphthalate is primarily used in sunscreens, moisturizers, and other skincare products as a key ingredient for providing broad-spectrum protection against both UVA and UVB rays. It helps prevent sunburn, premature aging, and skin cancer caused by prolonged exposure to the sun.

3. Usage Diethylhexyl 2,6 Naphthalate:

When using cosmetics containing Diethylhexyl 2,6 Naphthalate, it is important to follow the product instructions carefully. Apply the sunscreen or skincare product generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or after swimming or sweating. It is recommended to avoid prolonged sun exposure, especially during peak hours when the sun's rays are strongest.

Precautions: While Diethylhexyl 2,6 Naphthalate is considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using a product containing DEHN to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Klamt, A., & Diedenhofen, M. (2019). Diethylhexyl 2,6-Naphthalate. In COSMOS - A Comprehensive Online Scientific Modeling System (pp. 1-5). Wiley-VCH Verlag GmbH & Co. KGaA.

- European Commission. (2018). SCCS - Scientific Committee on Consumer Safety. Opinion on Diethylhexyl 2,6-Naphthalate. Retrieved from https://ec.europa.eu/health/sites/default/files/scientific_committees/consumer_safety/docs/sccs_o_217.pdf

- U.S. Food and Drug Administration. (2020). Sunscreen: How to Help Protect Your Skin from the Sun. Retrieved from https://www.fda.gov/consumers/consumer-updates/sunscreen-how-help-protect-your-skin-sun