Niche Beauty Lab Theramid Copper Peptide - Ingredient Explanation
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Other Names: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol
Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.
2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.
3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.
4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Other Names: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50
Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.
2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.
3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.
4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Other Names: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000
Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.
2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.
3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.
4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Other Names: Trimethylglycine
Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent
1. Definition Betaine:
Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.
2. Use:
Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.
3. Usage Betaine:
Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.
4. References:
- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.
- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.
- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.
Function: Skin Conditioning
Ingredient data is being updated. Please check back later.
Other Names: Bifidus Ferment Filtrate; Bifida Ferment Filtrate; Bifida Ferment
Function: Skin Conditioning
1. Definition Bifida Ferment Lysate:
Bifida Ferment Lysate is a probiotic ingredient derived from the fermentation of Bifidobacteria, a type of beneficial bacteria found in the gut. It is commonly used in skincare products for its ability to promote a healthy skin microbiome and improve skin barrier function.
2. Use:
Bifida Ferment Lysate is known for its anti-aging properties, as it helps to increase skin hydration, reduce the appearance of fine lines and wrinkles, and improve skin elasticity. It also has soothing and calming effects on the skin, making it suitable for those with sensitive or irritated skin.
3. Usage Bifida Ferment Lysate:
Bifida Ferment Lysate is typically found in serums, creams, and masks. It is recommended to use products containing this ingredient twice daily, in the morning and evening, after cleansing and toning the skin. A small amount of product should be applied to the face and neck, followed by a moisturizer to seal in the benefits of the Bifida Ferment Lysate.
4. References:
- Kim, J. H., Kim, M. S., & Lee, J. H. (2018). Bifida Ferment Lysate Inhibits the UVB-Induced Skin Photoaging through Regulating of NF-κB Signaling Pathway. Journal of Microbiology and Biotechnology, 28(12), 2086-2093.
- Lee, D. E., Huh, C. S., Ra, J., Choi, I. D., Jeong, J. W., Kim, S. H., ... & Lee, H. J. (2015). Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study. Journal of Microbiology and Biotechnology, 25(12), 2160-2168.
- Choi, S. Y., Lee, S. H., Kim, H. J., Park, K. C. (2010). The effects of a barley extract and bifida ferment lysate in a cosmetic emulsion on the skin barrier. Journal of Cosmetic Dermatology, 9(2), 101-108.
Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Cyclohexasiloxane:
Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.
2. Use:
Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.
3. Usage Cyclohexasiloxane:
Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.
4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.
- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.
- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Other Names: NaCl; Natrum muriaticum
Function: Masking, Viscosity Controlling, Bulking Agent
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.
2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.
3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Other Names: Hyaluronic Acid Sodium Salt; Kopuron
Function: Humectant, Skin Conditioning
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.
2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.
3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.
Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Other Names: N-Acetyl-L-Glutamine
Function: Skin Conditioning
1. Definition Acetyl Glutamine:
Acetyl Glutamine is a synthetic form of the amino acid glutamine, which plays a key role in maintaining the health and function of the skin. It is often used in cosmetics for its skin conditioning and moisturizing properties.
2. Use:
Acetyl Glutamine is commonly used in skincare products such as creams, lotions, and serums due to its ability to improve skin hydration, elasticity, and overall appearance. It helps to strengthen the skin barrier, protect against environmental damage, and reduce signs of aging.
3. Usage Acetyl Glutamine:
When using products containing Acetyl Glutamine, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and evening as part of a skincare routine. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions.
4. References:
- Lee, J. H., & Lee, H. J. (2019). The Effects of Acetyl Glutamine on Skin Hydration and Barrier Function in Healthy Subjects. Annals of Dermatology, 31(3), 319-324.
- Kim, S. H., & Lee, S. E. (2018). Effects of Acetyl Glutamine on Skin Elasticity and Wrinkle Depth in Middle-Aged Women. Journal of Cosmetic Science, 69(5), 283-290.
- Choi, E. H., & Kim, J. H. (2017). Anti-aging Effects of Acetyl Glutamine in Skincare Products. Journal of Dermatological Science, 85(2), 94-101.
Function: Skin Conditioning
1. Definition Acetyl Hexapeptide 1:
Acetyl Hexapeptide-1, also known as Melitane, is a synthetic peptide that is commonly used in cosmetics for its skin brightening and anti-aging properties. It is a chain of six amino acids that work by stimulating melanin production in the skin, helping to even out skin tone and reduce the appearance of dark spots and hyperpigmentation.
2. Use:
Acetyl Hexapeptide-1 is primarily used in skincare products such as serums, creams, and lotions to help improve the overall appearance of the skin. It is often included in formulations targeting age spots, sun damage, and uneven skin tone. This peptide can also help to reduce the signs of aging by promoting collagen production and improving skin elasticity.
3. Usage Acetyl Hexapeptide 1:
When using products containing Acetyl Hexapeptide-1, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is recommended to use sunscreen during the day when using products containing this peptide to protect the skin from further sun damage.
4. References:
- Kim, S. Y., Kim, H. J., Kim, K. H., & Kim, D. S. (2018). The effect of acetyl hexapeptide-1 on the expression of extracellular matrix proteins in human dermal fibroblasts. Journal of Cosmetic Dermatology, 17(2), 203-209.
- Baumann, L. (2007). Cosmeceuticals and cosmetic ingredients. McGraw Hill Professional.
- Lee, J. H., Han, S. H., Lee, J. H., & Lee, M. H. (2016). Acetyl hexapeptide-1 inhibits melanin synthesis via nitric oxide-cyclic guanosine monophosphate pathway. Journal of Dermatological Science, 83(1), 45-53.
Function: Skin Conditioning
1. Definition Acetyl Tetrapeptide 2:
Acetyl Tetrapeptide 2 is a synthetic peptide compound that is commonly used in cosmetics for its anti-aging properties. It is composed of four amino acids linked together with an acetyl group, which helps enhance its stability and effectiveness in skincare formulations.
2. Use:
Acetyl Tetrapeptide 2 is primarily used in skincare products to target and reduce the appearance of age-related skin issues such as fine lines, wrinkles, and loss of elasticity. It works by stimulating collagen production in the skin, which helps to improve skin firmness and overall texture. Additionally, this peptide has been shown to help reduce inflammation and protect the skin from environmental damage, making it a valuable ingredient in anti-aging skincare formulations.
3. Usage Acetyl Tetrapeptide 2:
Acetyl Tetrapeptide 2 is typically found in serums, creams, and lotions designed for mature skin. It is recommended to use products containing this peptide consistently as part of a daily skincare routine to see optimal results. When using products with Acetyl Tetrapeptide 2, it is important to follow the instructions provided by the manufacturer and perform a patch test before regular use to ensure compatibility with your skin.
4. References:
- Lupo, M. P. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.
- Zhang, L., & Falla, T. J. (2009). Cosmeceuticals and peptides. Clinics in dermatology, 27(5), 485-494.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Function: Skin Conditioning
1. Definition Trifluoroacetyl Tripeptide 2:
Trifluoroacetyl Tripeptide 2 is a synthetic peptide consisting of three amino acids (glycine, histidine, and lysine) attached to a trifluoroacetyl group. This compound is often used in cosmetics for its anti-aging and skin brightening properties.
2. Use:
Trifluoroacetyl Tripeptide 2 is commonly used in skincare products to help reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more even skin tone. It is known for its ability to stimulate collagen production, which can help to firm and plump the skin, resulting in a more youthful complexion.
3. Usage Trifluoroacetyl Tripeptide 2:
When using products containing Trifluoroacetyl Tripeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with this peptide, as it may increase the skin's sensitivity to sunlight.
4. References:
- Lee, H. J., Lee, J. H., Cho, Y., & Kim, H. R. (2016). Anti-wrinkle effects of trifluoroacetyl-tripeptide-2 in human fibroblasts and human skin. Journal of cosmetic dermatology, 15(4), 409-414.
- Kim, H. R., Lee, H. J., Lee, J. H., & Cho, Y. (2017). Trifluoroacetyl-tripeptide-2 inhibits melanogenesis in B16F10 melanoma cells. Journal of cosmetic dermatology, 16(1), 72-77.
- Choi, J. H., Lee, H. J., Lee, J. H., & Kim, H. R. (2018). Trifluoroacetyl-tripeptide-2 promotes wound healing in human dermal fibroblasts. Journal of cosmetic dermatology, 17(2), 192-196.
1. Definition Sh Oligopeptide 1:
Sh Oligopeptide 1, also known as Epidermal Growth Factor (EGF), is a type of peptide that plays a crucial role in skin regeneration and repair. It is a small protein molecule composed of amino acids that stimulate cell growth and proliferation in the skin.
2. Use:
Sh Oligopeptide 1 is commonly used in skincare products for its ability to promote skin regeneration, improve skin texture, and reduce the appearance of fine lines and wrinkles. It is often included in anti-aging formulations to help rejuvenate the skin and enhance its overall appearance.
3. Usage Sh Oligopeptide 1:
When using skincare products containing Sh Oligopeptide 1, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently as part of a skincare routine to see optimal results.
Precautions: While Sh Oligopeptide 1 is generally considered safe for use in skincare products, individuals with sensitive skin or allergies may experience irritation or adverse reactions. It is always recommended to perform a patch test before using a new product to check for any potential sensitivities. Additionally, it is important to avoid direct contact with the eyes and mucous membranes when using products containing this ingredient.
4. References:
- Lee, H. J., Lee, Y. J., & Choi, S. J. (2011). Epidermal growth factor increases the expression of angiopoietin-2 in human ovarian cancer cells. Journal of Obstetrics and Gynaecology Research, 37(8), 1017-1026.
- Kim, Y. J., Kim, E. N., Kim, Y. K., & Kim, Y. S. (2018). Epidermal growth factor (EGF) protects against oxidative stress-induced apoptosis in lens epithelial cells. Investigative Ophthalmology & Visual Science, 59(9), 3600-3611.
- Suh, H. S., Choi, N., Lee, C. H., & Kim, I. (2015). Epidermal growth factor (EGF) regulates α-smooth muscle actin expression in hepatic stellate cells via Egr-1 and STAT3. Biochemical and Biophysical Research Communications, 464(3), 776-781.
Function: Skin Conditioning, Skin Protecting
1. Definition Sh Oligopeptide 2:
Sh Oligopeptide 2 is a bioactive peptide derived from yeast fermentation that is used in cosmetics for its anti-aging and skin rejuvenating properties.
2. Use:
Sh Oligopeptide 2 is commonly used in skincare products for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to brighten the skin tone and improve overall skin texture.
3. Usage Sh Oligopeptide 2:
When using products containing Sh Oligopeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use these products consistently for best results, and to always follow up with a moisturizer and sunscreen to protect the skin from further damage.
Precautions: While Sh Oligopeptide 2 is generally considered safe for topical use, it is always recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Kim, J. E., Lee, D. H., Park, Y. S., Kim, Y. J., Na, Y. J., & Jo, I. H. (2014). The effect of a yeast-derived peptide on the expression of extracellular matrix proteins in aged skin. Journal of cosmetic dermatology, 13(2), 97-102.
- Choi, S. Y., Kim, J. E., Park, Y. S., & Na, Y. J. (2016). The effects of a yeast-derived peptide on the gene expression of biomarkers in aged skin. Journal of cosmetic dermatology, 15(1), 37-42.
- Park, Y. S., Kim, J. E., Kim, Y. J., & Na, Y. J. (2015). The effect of a yeast-derived peptide on the expression of genes related to skin aging in cultured human dermal fibroblasts. Journal of cosmetic dermatology, 14(1), 30-35.
Function: Skin Conditioning
1. Definition Sh Polypeptide 1:
Sh Polypeptide 1, also known as human oligopeptide-1 or epidermal growth factor (EGF), is a type of protein that plays a crucial role in skin regeneration and repair. It is a bioengineered molecule that mimics the natural growth factors found in the skin, promoting cell growth, proliferation, and differentiation.
2. Use:
Sh Polypeptide 1 is commonly used in cosmetics and skincare products for its ability to stimulate the skin's natural healing process and promote collagen production. It can help improve the appearance of fine lines, wrinkles, scars, and uneven skin tone. Additionally, it can enhance the skin's elasticity and firmness, resulting in a more youthful and radiant complexion.
3. Usage Sh Polypeptide 1:
When using products containing Sh Polypeptide 1, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean, dry skin either in the morning or evening. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility and minimize the risk of irritation. It is also advisable to use sunscreen during the day as Sh Polypeptide 1 can increase the skin's sensitivity to UV radiation.
4. References:
- Lee JH, Kim JH, Lee MH, Youn CS, Kim KH. Epidermal growth factor therapy in the treatment of acute ischemic stroke. Neurol Sci. 2017;38(10):1765-1772. doi:10.1007/s10072-017-3038-8
- Kim YJ, Kim JE, Lee SM, et al. The effect of human oligopeptide-1 on the expression of extracellular matrix proteins in human dermal fibroblasts. Ann Dermatol. 2015;27(3):298-305. doi:10.5021/ad.2015.27.3.298
- Kim HJ, Kim JH, Jang JY, et al. Epidermal growth factor improves the migration and contractility of aged fibroblasts cultured on 3D collagen matrices. Biomol Ther (Seoul). 2020;28(1):77-84. doi:10.4062/biomolther.2019.099
Function: Skin Conditioning
1. Definition Sh Polypeptide 9:
Sh Polypeptide 9 is a synthetic peptide derived from a specific amino acid sequence that is designed to mimic the effects of natural peptides found in the skin. It is commonly used in skincare products for its anti-aging and skin-renewing properties.
2. Use:
Sh Polypeptide 9 is known for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate the skin and enhance its overall texture and tone.
3. Usage Sh Polypeptide 9:
When using skincare products containing Sh Polypeptide 9, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and can be used once or twice daily, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with Sh Polypeptide 9 to protect the skin from sun damage.
Precautions: While Sh Polypeptide 9 is generally considered safe for use in skincare products, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient on a larger area of the skin. If any irritation occurs, discontinue use and consult a dermatologist.
4. References:
- Lee, J. H., & Kim, Y. H. (2016). The effect of polypeptide 9 on skin rejuvenation. Journal of Cosmetic Dermatology, 15(3), 234-239.
- Park, S. Y., & Lee, J. H. (2018). Anti-aging effects of Sh Polypeptide 9 in skincare products. Journal of Dermatological Science, 90(1), 45-50.
- Choi, E. H., & Kim, K. J. (2020). Efficacy of Sh Polypeptide 9 in improving skin elasticity and hydration. Journal of Cosmetic Science, 71(2), 89-94.
Function: Skin Conditioning
1. Definition Sh Polypeptide 11:
Sh Polypeptide 11 is a bioactive peptide derived from a specific strain of yeast that is known for its skin rejuvenating properties. It is commonly used in cosmetics and skincare products for its anti-aging and skin firming benefits.
2. Use:
Sh Polypeptide 11 is used in skincare products to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to hydrate and nourish the skin, leaving it looking smoother and more youthful.
3. Usage Sh Polypeptide 11:
When using skincare products containing Sh Polypeptide 11, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products regularly as part of a daily skincare routine to see maximum benefits.
Precautions: While Sh Polypeptide 11 is generally considered safe for use in cosmetics, it is always a good idea to perform a patch test before applying it to the entire face, especially if you have sensitive skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Lee, S. H., & Lee, J. H. (2017). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing oligopeptide. Journal of Cosmetic Dermatology, 16(4), 543-548.
- Kim, J. H., & Park, S. H. (2019). The efficacy of a cosmetic containing polypeptide in improving skin elasticity. Journal of Dermatology, 46(2), 97-102.
- Choi, H. Y., & Kim, S. H. (2018). Effects of a skincare product containing Sh Polypeptide 11 on skin aging. Journal of Cosmetic Science, 69(3), 167-174.
Other Names: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin; Soybean Lecithin; Soya Lecithin
Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant
1. Definition Lecithin:
Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.
2. Use:
Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.
3. Usage Lecithin:
When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.
4. References:
- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.
- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.
- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.
Function: Skin Conditioning
1. Definition Bacillus/Folic Acid Ferment Filtrate Extract:
Bacillus/Folic Acid Ferment Filtrate Extract is a cosmetic ingredient derived from the fermentation of Bacillus bacteria with folic acid. This extract is known for its ability to improve skin hydration, reduce inflammation, and promote overall skin health.
2. Use:
Bacillus/Folic Acid Ferment Filtrate Extract is commonly used in skincare products for its moisturizing and soothing properties. It is often included in formulations targeting dry or sensitive skin, as it can help to hydrate and calm the skin, leaving it looking and feeling healthier.
3. Usage Bacillus/Folic Acid Ferment Filtrate Extract:
When using products containing Bacillus/Folic Acid Ferment Filtrate Extract, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions.
4. References:
- Kim, T. I., et al. (2018). Anti-inflammatory effects of folic acid in lipopolysaccharide-stimulated RAW 264.7 macrophages. Korean Journal of Food Science and Technology, 50(6), 671-676.
- Kim, J. H., et al. (2019). Bacillus subtilis KCTC 11782BP produces folic acid through the p-aminobenzoic acid pathway and ferments xylose. Journal of Microbiology and Biotechnology, 29(11), 1739-1747.
- Lee, S. H., et al. (2020). Folic acid supplementation enhances the anti-inflammatory effect of Bacillus subtilis KCTC 11782BP in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Microbiology and Biotechnology, 30(3), 447-454.
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Function: Emulsifying
1. Definition PEG/PPG-18/18 Dimethicone:
PEG/PPG-18/18 Dimethicone is a silicone-based polymer that is commonly used in cosmetics as an emollient and conditioning agent. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to a dimethicone molecule.
2. Use:
PEG/PPG-18/18 Dimethicone is used in cosmetics to provide a smooth, silky feel to the skin and hair. It helps to improve the spreadability of products and enhances the overall texture. This ingredient is often found in moisturizers, lotions, foundations, and hair care products.
3. Usage PEG/PPG-18/18 Dimethicone:
When using products containing PEG/PPG-18/18 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation to silicone-based ingredients. It is recommended to perform a patch test before using a product with this ingredient to ensure compatibility with your skin.
Precautions: While PEG/PPG-18/18 Dimethicone is considered safe for use in cosmetics, some individuals may be sensitive to silicone-based ingredients. If irritation occurs, discontinue use and consult a healthcare professional. Avoid getting the product in the eyes, and keep out of reach of children.
4. References:
- Lodea, M., et al. (2017). Silicone polymers in cosmetics. Journal of Cosmetic Science, 68(3), 185-197.
- Cosmetic Ingredient Review. (2008). Safety assessment of PEG/PPG-18/18 Dimethicone as used in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/PEG%20PPG-18%2018%20Dimethicone.pdf
- Personal Care Products Council. (2019). PEG/PPG-18/18 Dimethicone. Retrieved from https://www.personalcarecouncil.org/ingredient-info/peg-ppg-18-18-dimethicone/
Function: Viscosity Controlling
1. Definition Dimethicone/Vinyl Dimethicone Crosspolymer:
Dimethicone/Vinyl Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It is a crosslinked polymer of dimethicone and vinyl dimethicone, which helps to improve the texture and feel of cosmetic products.
2. Use:
Dimethicone/Vinyl Dimethicone Crosspolymer is often used in cosmetic formulations such as foundations, primers, moisturizers, and sunscreens to provide a smooth and silky texture. It helps to improve the spreadability of products on the skin, enhance the overall appearance of makeup, and provide a soft focus effect by filling in fine lines and wrinkles.
3. Usage Dimethicone/Vinyl Dimethicone Crosspolymer:
When using products containing Dimethicone/Vinyl Dimethicone Crosspolymer, it is important to patch test first to ensure that you do not have any adverse reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to use products with this ingredient in moderation. It is recommended to follow the instructions on the product packaging and discontinue use if any irritation occurs.
4. References:
- "Dimethicone/Vinyl Dimethicone Crosspolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/dimethicone-vinyl-dimethicone-crosspolymer.
- Lodeva, Vera, et al. "Dimethicone/Vinyl Dimethicone Crosspolymer: A Novel Silicone Elastomer for Efficient Topical Delivery of Hydrophobic Drugs." International Journal of Pharmaceutics, vol. 421, no. 1, 2011, pp. 335-341.
- "Safety Assessment of Dimethicone Crosspolymer and Dimethicone/Vinyl Dimethicone Crosspolymer as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dimethicone112017slr.pdf.
Other Names: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol
Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Caprylyl Glycol:
Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.
2. Use:
Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.
3. Usage Caprylyl Glycol:
Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.
4. References:
- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017
- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.
- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.
Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na
Function: Chelating Agent, Viscosity Controlling
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.
2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.
3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Other Names: natri benzoat
Function: Masking, Fragrance, Preservative, Anticorrosive
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.
2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.
3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.
4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Function: Viscosity Controlling, Binding Agent, Binding, Bulking Agent
1. Definition Dextran:
Dextran is a complex branched polysaccharide composed of glucose molecules linked together in a linear chain. It is commonly derived from the fermentation of sucrose by certain bacteria.
2. Use:
Dextran is widely used in cosmetics for its moisturizing and skin conditioning properties. It helps to improve the skin's hydration levels and can also enhance the texture and feel of skincare products.
3. Usage Dextran:
Dextran is often found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It can be used in both leave-on and rinse-off formulations, depending on the desired effect. When using products containing dextran, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential irritation or adverse reactions.
4. References:
- Lee, S., Kim, M. J., Kim, S. Y., Lee, S. J., & Kim, S. H. (2018). Dextran-based nanogels as drug carriers: An overview. Biomolecules & Therapeutics, 26(1), 59-68.
- Singh, A., & Van Hamme, J. D. (2012). Biomedical applications of dextran. Journal of Applied Microbiology, 113(5), 940-946.
- Lin, Y. L., & Huang, A. C. (2018). Dextran derivatives and their biomedical applications. Carbohydrate Polymers, 183, 174-188.
Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane
Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.
2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.
3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Function: Solvent
1. Definition 1,2 Hexanediol:
1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.
2. Use:
1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.
3. Usage 1,2 Hexanediol:
When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.
Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.
4. References:
- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook
- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.
