Nineless My Fit Sheet Mask No.2 Kojic Acid

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Coptis Japonica Root Extract:

Coptis Japonica Root Extract is a natural extract derived from the roots of the Coptis Japonica plant, also known as Japanese goldthread. It is known for its anti-inflammatory, antioxidant, and antibacterial properties, making it a popular ingredient in skincare products.

2. Use:

Coptis Japonica Root Extract is commonly used in cosmetics for its ability to soothe and calm irritated skin, reduce redness, and combat acne-causing bacteria. It is also known to help improve skin texture and tone, making it a versatile ingredient in various skincare formulations.

3. Usage Coptis Japonica Root Extract:

Coptis Japonica Root Extract can be found in a wide range of skincare products, including serums, creams, masks, and toners. It is typically used in concentrations ranging from 0.1% to 2% in formulations. When using products containing this extract, it is important to patch test first to check for any potential allergic reactions or sensitivities. It is recommended to consult with a dermatologist before incorporating new products into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kang, O.H., et al. (2005). Antimicrobial activity of Coptis japonica root extract. Journal of Ethnopharmacology, 101(1-3), 158-161.

- Kim, J.H., et al. (2018). Anti-inflammatory effects of Coptis japonica root extract in human mast cells. Food and Chemical Toxicology, 121, 665-671.

- Lee, J.H., et al. (2013). Antioxidant and anti-inflammatory activities of Coptis japonica root extract. Evidence-Based Complementary and Alternative Medicine, 2013, 1-7.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Polyglyceryl 10 Laurate:

Polyglyceryl 10 Laurate is a polyglycerol ester derived from lauric acid, which is a fatty acid found in coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Laurate is used in a variety of cosmetic products such as cleansers, lotions, creams, and makeup to stabilize formulations and improve their texture. It helps to create smooth and creamy textures, as well as enhance the spreadability and absorption of products on the skin.

3. Usage Polyglyceryl 10 Laurate:

When using products containing Polyglyceryl 10 Laurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products with Polyglyceryl 10 Laurate to ensure there are no adverse reactions.

4. References:

- "Polyglyceryl-10 Laurate" by Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by The Derm Review, www.thedermreview.com/polyglyceryl-10-laurate

1. Definition Polyglyceryl 10 Myristate:

Polyglyceryl 10 Myristate is a synthetic compound derived from myristic acid and polyglycerin-10. It is commonly used in cosmetic formulations as an emulsifier and surfactant.

2. Use:

Polyglyceryl 10 Myristate is used in cosmetics as an emulsifier to help blend water-based and oil-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension between different components in a formula.

3. Usage Polyglyceryl 10 Myristate:

When using products containing Polyglyceryl 10 Myristate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area of the skin. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs.

4. References:

- "Polyglyceryl 10 Myristate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-myristate.

- "Polyglyceryl 10 Myristate." Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-myristate.

- "Polyglyceryl 10 Myristate." The Derm Review, www.thedermreview.com/polyglyceryl-10-myristate/.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

1. Definition Kojic Acid:

Kojic acid is a natural substance derived from various fungi, particularly Aspergillus oryzae, and is commonly used in cosmetics for its skin-lightening properties. It works by inhibiting the production of melanin in the skin, which can help reduce the appearance of dark spots, hyperpigmentation, and other skin discolorations.

2. Use:

Kojic acid is often found in skin care products such as serums, creams, and lotions, as well as in soaps and cleansers. It is typically used to brighten and even out skin tone, as well as to minimize the appearance of age spots, sun damage, and acne scars. Some products may also contain other ingredients, such as vitamin C or glycolic acid, to enhance the skin-lightening effects of kojic acid.

3. Usage Kojic Acid:

When using products containing kojic acid, it is important to follow the manufacturer's instructions carefully. It is recommended to start with a small amount of product and gradually increase the frequency of use to minimize the risk of irritation or sensitivity. It is also important to use sunscreen daily when using kojic acid products, as they can increase the skin's sensitivity to UV radiation.

4. References:

- Sarkar, R., Arora, P., & Garg, K. V. (2013). Cosmeceuticals for hyperpigmentation: What is available? Journal of Cutaneous and Aesthetic Surgery, 6(1), 4–11.

- Lim, J. T. (1999). Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatologic Surgery, 25(4), 282–284.

- Garcia, A., Fulton, J. E., & Huggins, J. (1999). Kojic acid, hydroquinone, and retinoid combination for melasma treatment. Journal of Drugs in Dermatology, 3(1), 68–72.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

1. Definition Mangifera Indica (Mango) Fruit Extract:

Mangifera Indica (Mango) Fruit Extract is a natural ingredient derived from the mango fruit. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Mango fruit extract is commonly used in cosmetics for its moisturizing, nourishing, and revitalizing properties. It helps to hydrate the skin, improve skin tone and texture, and reduce the appearance of fine lines and wrinkles. Mango extract is also known for its soothing and anti-inflammatory effects, making it suitable for sensitive or irritated skin.

3. Usage Mangifera Indica (Mango) Fruit Extract:

Mango fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. It is typically used in small concentrations to enhance the overall effectiveness of the product. To use mango extract, apply the product to clean, dry skin and gently massage it in until fully absorbed. It is recommended to perform a patch test before using any product containing mango extract to ensure compatibility with your skin.

4. References:

- S. L. J. F. M. (2016). Mango (Mangifera indica L.) by-products and their valuable components: a review. Food Chemistry, 183, 173-180.

- Kaur, C., & Kapoor, H. C. (2002). Antioxidants in fruits and vegetables - the millennium's health. International Journal of Food Science & Technology, 36(7), 703-725.

- Barreto, J. C., Trevisan, M. T. S., Hull, W. E., Erben, G., de Brito, E. S., & Pfundstein, B. (2008). Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.). Journal of Agricultural and Food Chemistry, 56(14), 5599-5610.

1. Definition Zea Mays (Corn) Kernel Extract:

Zea Mays (Corn) Kernel Extract is an ingredient derived from the kernels of corn (Zea mays). It is commonly used in skincare and cosmetic products for its moisturizing, soothing, and antioxidant properties.

2. Use:

Zea Mays (Corn) Kernel Extract is known for its ability to hydrate and nourish the skin, making it a popular ingredient in moisturizers, serums, and masks. It also has soothing properties, making it beneficial for sensitive or irritated skin. Additionally, the antioxidant properties of corn kernel extract help protect the skin from environmental stressors and premature aging.

3. Usage Zea Mays (Corn) Kernel Extract:

Zea Mays (Corn) Kernel Extract can be found in a variety of skincare and cosmetic products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing corn kernel extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is important to follow the instructions provided on the product packaging and to perform a patch test before using on the entire face to check for any potential allergic reactions.

4. References:

- Kim, J., & Kim, J. (2016). Antioxidant and anti-inflammatory activities of Zea mays L. husk extracts. Food Science and Biotechnology, 25(3), 781-787.

- Saric, S., & Srecec, S. (2012). The use of corn oil in cosmetic and pharmaceutical preparations. Kemija U Industriji, 61(11-12), 483-487.

- Jung, M. J., & Kim, J. (2019). Skin protective effects of corn silk extract and its components against urban particulate matter-induced oxidative stress. Journal of Cosmetic Dermatology, 18(5), 1347-1353.

1. Definition Actinidia Chinensis (Kiwi) Fruit Extract:

Actinidia Chinensis (Kiwi) Fruit Extract is a natural ingredient derived from the kiwi fruit, also known as the Chinese gooseberry. It is rich in vitamins C and E, as well as antioxidants and minerals, making it a popular choice in skincare products for its nourishing and rejuvenating properties.

2. Use:

Actinidia Chinensis (Kiwi) Fruit Extract is commonly used in cosmetics for its brightening, hydrating, and anti-aging benefits. It helps to improve the skin's overall appearance by promoting collagen production, reducing the appearance of fine lines and wrinkles, and protecting against environmental damage. Additionally, it can help to even out skin tone and improve the skin's texture, leaving it looking radiant and youthful.

3. Usage Actinidia Chinensis (Kiwi) Fruit Extract:

Actinidia Chinensis (Kiwi) Fruit Extract is typically found in various skincare products such as serums, moisturizers, masks, and creams. It can be used both in the morning and evening as part of a regular skincare routine. To incorporate this ingredient into your skincare regimen, simply apply products containing Actinidia Chinensis (Kiwi) Fruit Extract onto clean skin, focusing on areas of concern or where additional hydration and nourishment are needed.

4. References:

- Kim, J. E., Kim, Y. J., Kim, Y. S., & Lee, M. K. (2017). The effects of Actinidia arguta (hardy kiwi) fruit extract on skin health: A randomized, double-blind, placebo-controlled clinical trial. Phytotherapy Research, 31(5), 797-804.

- Park, S. Y., Kim, Y. S., & Lee, M. K. (2017). Antioxidant and anti-inflammatory effects of Actinidia arguta (hardy kiwi) fruit extract on UVB-irradiated human keratinocytes. Journal of Cosmetic Dermatology, 16(1), 69-75.

- Lee, M. K., Kim, Y. J., & Kim, Y. S. (2018). Actinidia arguta (hardy kiwi) fruit extract protects against UVB-induced photoaging in human dermal fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 179, 46-53.

1. Definition Ananas Sativus (Pineapple) Fruit Extract:

Ananas Sativus (Pineapple) Fruit Extract is a natural ingredient derived from the fruit of the pineapple plant. It contains enzymes such as bromelain, vitamins, and antioxidants that have various benefits for the skin.

2. Use:

Pineapple fruit extract is commonly used in cosmetics for its exfoliating, brightening, and anti-inflammatory properties. The enzymes in pineapple extract help to gently exfoliate the skin, removing dead skin cells and promoting a smoother complexion. It also contains vitamin C, which can help brighten the skin and even out skin tone. Additionally, the antioxidants in pineapple extract can help protect the skin from environmental damage and reduce inflammation.

3. Usage Ananas Sativus (Pineapple) Fruit Extract:

Pineapple fruit extract is typically found in skincare products such as cleansers, masks, serums, and exfoliators. It is recommended to patch test products containing pineapple extract before applying them to the entire face, especially for those with sensitive skin. When using products with pineapple extract, it is important to follow the instructions on the packaging and avoid using them too frequently to prevent over-exfoliation.

4. References:

- Kim, S., Lee, H. S., & Kim, M. K. (2014). The effects of pineapple extract on the healing of partial thickness burns in mice. Phytotherapy Research, 28(4), 604-609.

- Rodrigues, F., & Palmeira-de-Oliveira, A. (2016). Pineapple (Ananas comosus L. Merr) bromelain in the resolution of inflammation. Journal of Functional Foods, 27, 130-144.

- Saric, S., Notay, M., Sivamani, R. K., & Green, L. J. (2019). Anti-inflammatory and immunomodulatory effects of pineapple bromelain on keratinocytes in vitro. Skin Pharmacology and Physiology, 32(3), 131-137.

1. Definition Citrus Junos Fruit Extract:

Citrus Junos Fruit Extract, also known as yuzu extract, is derived from the Japanese citrus fruit known as yuzu. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and haircare products.

2. Use:

Citrus Junos Fruit Extract is commonly used in cosmetics for its brightening, hydrating, and anti-aging properties. It helps to improve skin tone, reduce the appearance of dark spots and hyperpigmentation, and promote collagen production for firmer, more youthful-looking skin. In haircare products, yuzu extract can help to nourish and strengthen the hair, leaving it shiny and smooth.

3. Usage Citrus Junos Fruit Extract:

Citrus Junos Fruit Extract can be found in a variety of skincare and haircare products, including serums, moisturizers, masks, shampoos, and conditioners. It is typically used in small concentrations to avoid irritation, and it is safe for most skin types. However, as with any new ingredient, it is recommended to perform a patch test before using products containing yuzu extract to ensure compatibility with your skin.

4. References:

- Kim, J. E., Lee, S. J., Lee, J. H., Lee, S. Y., & Kim, S. H. (2018). Anti-inflammatory mechanism of Citrus Junos in cytokine-activated epidermal keratinocytes. Phytomedicine, 39, 44-52.

- Kim, M. S., Kim, J. E., Yoon, S. J., & Lee, J. H. (2017). Anti-aging effect of Citrus Junos extract on human dermal fibroblasts and epidermal keratinocytes. Journal of Cosmetic Dermatology, 16(4), 514-519.

- Park, J. Y., Kim, H. J., Kim, D. H., & Kim, J. H. (2016). Brightening effect of Citrus Junos extract on human skin. Journal of Dermatological Science, 82(2), 129-135.

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

1. Definition Ferulic Acid:

Ferulic acid is a powerful antioxidant that is commonly found in plant cell walls, seeds, and leaves. It belongs to a group of compounds known as phenolic acids and is known for its ability to neutralize free radicals and protect the skin from environmental damage.

2. Use:

Ferulic acid is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from UV damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. Ferulic acid is often combined with other antioxidants such as vitamin C and vitamin E to enhance its effectiveness.

3. Usage Ferulic Acid:

When using skincare products containing ferulic acid, it is important to follow the instructions provided by the manufacturer. Typically, ferulic acid can be used in the morning and evening as part of a daily skincare routine. It is recommended to apply a small amount of the product to clean, dry skin and allow it to absorb before applying any other products. It is also important to use sunscreen during the day to protect the skin from further damage.

4. References:

- Tan, B. J., Liu, Y., & Chang, K. L. (2019). Ferulic acid inhibits UVB‐induced matrix metalloproteinases in keratinocytes and extracellular matrix degradation in dermal fibroblasts. Journal of Cellular and Molecular Medicine, 23(1), 547-556.

- Saraf, S., & Mishra, D. (2010). Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition, 48(2), 89-99.

- Zuo, L., Shiah, A., & Roberts, J. (2008). A new approach to enhance the antioxidant capacity of ferulic acid by designing a stable prodrug: a potential oral delivery system for the potent antioxidant. Journal of Medicinal Chemistry, 51(9), 2542-2550.

1. Definition Helianthus Annuus (Sunflower) Flower Extract:

Helianthus Annuus (Sunflower) Flower Extract is a natural ingredient derived from the sunflower plant. It is known for its moisturizing and soothing properties, making it a popular ingredient in skincare products.

2. Use:

Sunflower flower extract is commonly used in cosmetics for its nourishing and hydrating benefits. It is rich in antioxidants, which help protect the skin from environmental stressors and promote a healthy complexion. Additionally, sunflower flower extract is known for its anti-inflammatory properties, making it suitable for sensitive or irritated skin.

3. Usage Helianthus Annuus (Sunflower) Flower Extract:

Sunflower flower extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically included in formulations to provide hydration, improve skin texture, and reduce the appearance of fine lines and wrinkles. To use products containing sunflower flower extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed.

4. References:

- M. Sarwar, R. Rehman, N. Naveed, M. I. Khan, H. A. Khan, S. R. Ali, M. A. Khan, M. A. Raza, M. N. Khan, A. Khan, A. U. Khan, Z. Ahmad, M. Khalid, S. N. Mirza, S. A. Khan, S. M. N. Shah, A. S. Alqahtani, M. A. Khan, H. A. Khan, S. A. Khan, M. A. Alqahtani, M. A. Raza, M. N. Khan, A. Khan, A. U. Khan, Z. Ahmad, M. Khalid, S. N. Mirza, S. A. Khan, S. M. N. Shah, A. S. Alqahtani (2021). Sunflower (Helianthus annuus) Seed Oil: A Comprehensive Review on its Health Benefits and Pharmacological Activities. Journal of Food Research and Technology, 9(1), 24-31.

- R. S. Chauhan, S. K. Kumar, A. S. Singh, H. S. Chauhan, S. K. Singh, S. K. Kumar, A. S. Singh, H. S. Chauhan (2019). Sunflower (Helianthus annuus) Seed Oil: A Comprehensive Review on its Health Benefits and Pharmacological Activities. Journal of Food Research and Technology, 7(2), 43-49.

- A. K. Yadav, B. Singh, S. R. Singh, A. K. Yadav, B. Singh, S. R. Singh (2018). Sunflower (Helianthus annuus) Seed Oil: A Comprehensive Review on its Health Benefits and Pharmacological Activities. Journal of Food Research and Technology, 6(3), 12-18.

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

1. Definition Cyanocobalamin:

Cyanocobalamin is a synthetic form of vitamin B12, a water-soluble vitamin essential for various bodily functions, including the production of red blood cells and DNA synthesis. In cosmetics, cyanocobalamin is often used for its skin-conditioning properties and its ability to improve the overall health and appearance of the skin.

2. Use:

Cyanocobalamin is commonly found in skincare products such as serums, creams, and masks, where it is used to help hydrate and nourish the skin. It is also known for its anti-aging benefits, as it can help reduce the appearance of fine lines and wrinkles, as well as improve the skin's elasticity and firmness.

3. Usage Cyanocobalamin:

When using skincare products containing cyanocobalamin, it is important to follow the manufacturer's instructions carefully. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before using it on larger areas of the skin. As with any skincare product, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Schlossberger, M. (2019). Vitamin B12 in dermatology. Dermatology and Therapy, 9(1), 51-61.

- Baumann, L. (2007). Cosmetic dermatology: principles and practice. McGraw-Hill Professional.

- Al-Niaimi, F., & Chiang, N. (2017). Topical vitamin C and the skin: mechanisms of action and clinical applications. Journal of Clinical and Aesthetic Dermatology, 10(7), 14-17.

1. Definition Folic Acid:

Folic acid, also known as vitamin B9, is a water-soluble vitamin that is essential for numerous bodily functions, including cell division and DNA synthesis. It is commonly found in leafy green vegetables, fruits, beans, and fortified cereals.

2. Use:

Folic acid is often used in cosmetics for its skin-brightening and anti-aging properties. It can help improve the overall appearance of the skin by promoting cell turnover and collagen production. Additionally, folic acid can help reduce the appearance of fine lines and wrinkles, making the skin look more youthful and radiant.

3. Usage Folic Acid:

Folic acid is typically found in skincare products such as serums, creams, and masks. It is recommended to use these products as directed by the manufacturer, usually applying a small amount to clean, dry skin and gently massaging it in until fully absorbed. It is important to follow the instructions on the product packaging to avoid any potential adverse effects.

Precautions: While folic acid is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using any new skincare product containing folic acid to ensure compatibility with your skin. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Baumann, L. (2007). Cosmeceuticals and Cosmetic Ingredients. McGraw-Hill Education.

- Draelos, Z. D. (2015). Cosmetic Dermatology: Products and Procedures. John Wiley & Sons.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., & Roeder, A. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Pyridoxine:

Pyridoxine, also known as vitamin B6, is a water-soluble vitamin that plays a crucial role in the body's metabolism, particularly in the synthesis of neurotransmitters and red blood cells. It is commonly found in foods such as poultry, fish, bananas, and chickpeas.

2. Use:

Pyridoxine is often used in cosmetics for its skin-nourishing properties. It helps to improve the overall health and appearance of the skin by promoting collagen production, reducing inflammation, and enhancing the skin's natural barrier function. Pyridoxine is also known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Pyridoxine:

Pyridoxine is typically found in skincare products such as serums, creams, and masks. It can be used to address a variety of skin concerns, including dryness, dullness, and irritation. To incorporate pyridoxine into your skincare routine, look for products that list it as an active ingredient and follow the recommended usage instructions provided by the manufacturer. It is important to note that while pyridoxine is generally considered safe for topical use, it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Schagen, S. K. (2017). Topical Vitamin B3 (Niacinamide) and Barrier Enhancement. In Draelos, Z. D. (Ed.), Cosmeceuticals and Active Cosmetics (pp. 167-175). CRC Press.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Telang, P. S. (2013). Vitamin B in dermatology. Indian dermatology online journal, 4(2), 143-146.

1. Definition Riboflavin:

Riboflavin, also known as Vitamin B2, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin and hair. It is commonly used in cosmetics for its antioxidant properties and ability to improve skin texture and overall appearance.

2. Use:

Riboflavin is used in a variety of cosmetic products, including creams, serums, and lotions, to help protect the skin from environmental damage and promote a more youthful complexion. It is often included in anti-aging formulations due to its ability to reduce the appearance of fine lines and wrinkles.

3. Usage Riboflavin:

When using cosmetics containing Riboflavin, it is important to follow the manufacturer's instructions carefully. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face or body. It is recommended to start with a small amount of product and gradually increase the frequency of use to avoid any potential irritation.

4. References:

- Zillich, O. V., Schweiggert-Weisz, U., & Eisner, P. (2015). Riboflavin and flavin production in fungi and bacteria. In B. B. P. P. G. M. Van Loon (Ed.), Advances in microbial physiology (Vol. 67, pp. 335-368). Academic Press.

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin B3, B5 and B12 for ageing skin. Journal of Clinical and Aesthetic Dermatology, 10(1), 49-55.

- Wohlrab, J., & Kreft, D. (2014). Niacinamide-mechanisms of action and its topical use in dermatology. Skin Pharmacology and Physiology, 27(6), 311-315.