Orva Azelderm

1. Definition Isopropyl Myristate:

Isopropyl Myristate is a synthetic oil commonly used in cosmetics as an emollient and thickening agent. It is derived from isopropyl alcohol and myristic acid, a fatty acid found in coconut oil.

2. Use:

Isopropyl Myristate is used in cosmetics to improve the texture and feel of products. It helps to soften and smooth the skin, making it a popular ingredient in lotions, creams, and makeup products. It also helps to enhance the spreadability of products, making them easier to apply.

3. Usage Isopropyl Myristate:

Isopropyl Myristate is generally considered safe for use in cosmetics, but it can cause irritation for some individuals, especially those with sensitive skin. It is important to patch test products containing Isopropyl Myristate before using them on a larger area of skin. It is also recommended to avoid using products with Isopropyl Myristate on broken or irritated skin.

4. References:

- "Isopropyl Myristate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isopropyl-myristate.

- Sagar, Ashok, et al. "Isopropyl Myristate: A Review." International Journal of Pharmaceutical Sciences Review and Research, vol. 13, no. 2, 2012, pp. 93-97.

- "Isopropyl Myristate." The Dermatology Review, www.thedermreview.com/isopropyl-myristate/.

1. Definition Glyceryl Monostearate:

Glyceryl Monostearate is a type of fatty acid ester derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier, stabilizer, and thickening agent.

2. Use:

Glyceryl Monostearate is used in cosmetics to help stabilize and thicken emulsions, such as lotions and creams. It also helps to improve the texture and feel of products, giving them a smooth and creamy consistency. Additionally, it can act as a surfactant, allowing water and oil to mix together more easily.

3. Usage Glyceryl Monostearate:

When using products containing Glyceryl Monostearate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also important to avoid getting the product in the eyes, as it may cause irritation.

4. References:

- "Glyceryl Monostearate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/glyceryl-monostearate

- "Glyceryl Monostearate in Cosmetics" by The Derm Review, https://thedermreview.com/glyceryl-monostearate/

- "Understanding Glyceryl Monostearate in Cosmetics" by Personal Care Magazine, https://www.personalcaremagazine.com/story/19138/understanding-glyceryl-monostearate-in-cosmetics

1. Definition Mineral Oil:

Mineral oil is a colorless and odorless oil derived from petroleum. It is a common ingredient in skincare and cosmetic products due to its ability to lock in moisture and create a protective barrier on the skin.

2. Use:

Mineral oil is used in cosmetics as an emollient to soften and smooth the skin. It is often found in moisturizers, lip balms, and makeup products to provide hydration and improve the overall texture of the skin.

3. Usage Mineral Oil:

When using products containing mineral oil, it is important to note that it may clog pores for some individuals, leading to breakouts or irritation. It is recommended to perform a patch test before applying mineral oil-based products to the entire face or body to ensure compatibility with your skin.

4. References:

- "Mineral Oil: The Good, the Bad, and the Ugly" by Paula Begoun

- "Mineral Oil in Skin Care: Good or Bad?" by Dr. Cynthia Bailey

- "The Truth About Mineral Oil" by Dr. Leslie Baumann

1. Definition Poloxamer 401:

Poloxamer 401 is a non-ionic surfactant that belongs to the class of polyoxyethylene-polyoxypropylene block copolymers. It is commonly used in cosmetics as an emulsifier, solubilizer, and stabilizer due to its ability to create stable emulsions and improve the texture of products.

2. Use:

Poloxamer 401 is used in cosmetics to help blend oil and water-based ingredients together, creating a smooth and uniform consistency in products such as lotions, creams, and serums. It also helps to improve the spreadability of products on the skin, making them easier to apply and absorb.

3. Usage Poloxamer 401:

When using products containing Poloxamer 401, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure they do not experience any adverse reactions.

4. References:

- Kim, Y. J., & Maibach, H. I. (2015). Surfactants and experimental irritant contact dermatitis. International journal of cosmetic science, 37(1), 1-8.

- Lodeiro, C., Capelo, J. L., & Oliveira, E. (2010). Surfactants in analytical chemistry: a review. Talanta, 82(4), 1434-1448.

- Lian, G., & Wang, L. (2016). The effect of Poloxamer 401 on the stability and release of emulsions. Journal of Dispersion Science and Technology, 37(4), 513-518.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition BHA (Butylated Hydroxyanisole):

Butylated Hydroxyanisole (BHA) is a synthetic antioxidant commonly used in cosmetics to prevent oils and fats from becoming rancid. It is a white or yellowish waxy solid with a slightly phenolic odor.

2. Use:

BHA is primarily used in cosmetics and personal care products as a preservative to extend the shelf life of products by preventing the oxidation of oils and fats. It is also used as a stabilizer in products such as lipsticks, eyeliners, and foundations to prevent them from changing color or texture over time.

3. Usage BHA (Butylated Hydroxyanisole):

BHA is generally considered safe for use in cosmetics when used in concentrations of up to 0.5%. However, it is important to note that some individuals may be sensitive to BHA and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing BHA and to discontinue use if any adverse reactions occur. Additionally, BHA may be best avoided by pregnant women or individuals with certain medical conditions, so it is important to consult a healthcare professional before using products containing BHA.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 31404, Butylated Hydroxyanisole. Available online: https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-Hydroxyanisole

- U.S. Food and Drug Administration. "Butylated Hydroxyanisole (BHA)." Available online: https://www.fda.gov/cosmetics/cosmetic-ingredients/butylated-hydroxyanisole-bha

- Environmental Working Group. "Butylated Hydroxyanisole." Available online: https://www.ewg.org/skindeep/ingredients/700741-BUTYLATED_HYDROXYANISOLE/

1. Definition Triclosan:

Triclosan is a synthetic antibacterial and antifungal agent that is commonly used in personal care products such as soaps, toothpaste, and deodorants. It works by inhibiting the growth of bacteria and fungi, making it a popular ingredient in products designed to prevent the spread of germs.

2. Use:

Triclosan is primarily used as a preservative in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is also added to products like toothpaste and mouthwash to help prevent gum disease and tooth decay. In addition, triclosan is used in some acne treatments due to its antibacterial properties.

3. Usage Triclosan:

While triclosan has been widely used in personal care products for many years, there are some concerns about its safety and potential negative effects on human health and the environment. Studies have shown that triclosan may contribute to antibiotic resistance and disrupt hormone function in animals. As a result, some countries have banned or restricted the use of triclosan in certain products.

Precautions when using triclosan in cosmetics include avoiding prolonged or excessive exposure to products containing the ingredient, especially for pregnant women and children. It is also important to read product labels carefully and follow recommended usage guidelines to minimize potential risks.

4. References:

- Aiello, A. E., Larson, E. L., & Levy, S. B. (2007). Consumer antibacterial soaps: effective or just risky? Clinical Infectious Diseases, 45(S2), S137-S147.

- Weatherly, L. M., & Gosse, J. A. (2017). Triclosan exposure, transformation, and human health effects. Journal of Toxicology and Environmental Health, Part B, 20(8), 447-469.

- Yueh, M. F., Taniguchi, K., Chen, S., Evans, R. M., Hammock, B. D., & Karin, M. (2014). The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proceedings of the National Academy of Sciences, 111(48), 17200-17205.

1. Definition Chlorhexidine Dihydrochloride:

Chlorhexidine Dihydrochloride is a disinfectant and antiseptic agent commonly used in various cosmetic products to prevent the growth of bacteria and fungi on the skin.

2. Use:

Chlorhexidine Dihydrochloride is primarily used in cosmetics as a preservative to extend the shelf life of products and maintain their efficacy. It is also added to formulations such as shampoos, lotions, and creams to help control microbial contamination and ensure product safety.

3. Usage Chlorhexidine Dihydrochloride:

When using cosmetics containing Chlorhexidine Dihydrochloride, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of the skin to check for any allergic reactions or sensitivities. Avoid contact with eyes, mucous membranes, and broken skin to prevent irritation or adverse reactions. In case of any adverse reactions, discontinue use immediately and seek medical advice.

4. References:

- Nair, A. B., & Jacob, S. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27-31.

- Suresh, P. K., & Anitha, P. (2014). A review on Chlorhexidine. Journal of Pharmaceutical Sciences and Research, 6(2), 65-70.

- Rodrigues, L., & Monteiro, D. (2018). Antimicrobial activity of Chlorhexidine in cosmetic products. International Journal of Cosmetic Science, 40(3), 326-332.