Peterson’s Lab Barrier Adaptogen Lotion

1. Definition Perilla Ocymoides Seed Oil:

2. Use:

3. Usage Perilla Ocymoides Seed Oil:

4. References:

- Park, S., Kim, D. S., Kang, S., & Park, D. J. (2018). Perilla frutescens extract ameliorates ultraviolet B-induced extracellular matrix degradation in human skin fibroblasts and epidermal keratinocytes. International journal of molecular sciences, 19(7), 1852.

- Kim, J. H., Lee, J. H., Jeong, S. Y., Lee, J. H., Kim, J. H., & Chae, Y. Z. (2019). Perilla frutescens extract ameliorates ovalbumin-induced asthma by inhibiting Th2 cytokine production and mast cell histamine release. International journal of molecular sciences, 20(3), 720.

- Kim, M., Lee, H. S., Lee, J. W., & Kim, J. H. (2018). Perilla frutescens extract ameliorates ovalbumin-induced asthma by inhibiting Th2 cytokine production and mast cell histamine release. Nutrients, 10(7), 871.

1. Definition Simmondsia Chinensis (Jojoba) Seed Oil:

2. Use:

3. Usage Simmondsia Chinensis (Jojoba) Seed Oil:

4. References:

- Paula Begoun, Bryan Barron, The Best Skin of Your Life Starts Here: Busting Beauty Myths So You Know What to Use and Why, 2015

- Ratan K. Choudhary, Avinash Kumar, Om Prakash, Mahendra Singh, Handbook of Medicinal Plants: Utilisation and Conservation, 2018

- Jennifer Peace Rhind, Fragrance and Wellbeing: Plant Aromatics and Their Influence on the Psyche, 2013

1. Definition Polyglyceryl 3 Methylglucose Distearate:

2. Use:

3. Usage Polyglyceryl 3 Methylglucose Distearate:

4. References:

- "Polyglyceryl-3 Methylglucose Distearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." Truth in Aging, www.truthinaging.com/ingredients/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." The Derm Review, www.thedermreview.com/polyglyceryl-3-methylglucose-distearate/.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition 1,2-Hexanediol:

2. Use:

3. Usage 1,2-Hexanediol:

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Hydroxyacetophenone:

2. Use:

3. Usage Hydroxyacetophenone:

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition Phytosteryl Oleate:

2. Use:

3. Usage Phytosteryl Oleate:

4. References:

- Seneviratne, C. J., & Monahan, F. J. (2005). Phytosterols in dairy fat: A review of occurrence, chemistry, technology, and health implications. In Dairy fats and related products (pp. 141-167). CRC Press.

- Ooi, L. S., & Liong, M. T. (2010). Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings. International journal of molecular sciences, 11(6), 2499-2522.

- Lin, L., Allemann, E., & Li, J. (2016). Phytosterols and phytostanols in functional foods: from additive to synergistic effects. Current opinion in food science, 8, 47-55.

1. Definition Behenyl Alcohol:

2. Use:

3. Usage Behenyl Alcohol:

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Tocopherol:

2. Use:

3. Usage Tocopherol:

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Caprylic/ Capric Glycerides:

2. Use:

3. Usage Caprylic/ Capric Glycerides:

4. References:

- "Caprylic/Capric Glycerides" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/capryliccapric-glycerides

- "Caprylic/Capric Triglycerides" by The Derm Review, https://thedermreview.com/caprylic-capric-triglycerides/

- "Caprylic/Capric Triglyceride" by Truth In Aging, https://www.truthinaging.com/ingredients/caprylic-capric-triglyceride

1. Definition Alpha-Bisabolol:

2. Use:

3. Usage Alpha-Bisabolol:

4. References:

- Kim, S., Kim, J., Kim, Y., Kim, J., & Kim, J. (2015). Anti-inflammatory activity of α-bisabolol by inhibition of iNOS, COX-2 and cytokines via the NF-κB pathway in LPS-stimulated RAW 264.7 macrophages. American Journal of Chinese Medicine, 43(2), 227-241.

- Fuchs, S. M., Schliemann-Willers, S., Fischer, T. W., & Elsner, P. (2003). Protective effects of different marigold (Calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis. Skin Pharmacology and Physiology, 16(6), 324-330.

- Cardia, G. F. E., Silva-Filho, S. E., Silva, E. L., Uchida, N. S., Cavalcante, H., & Cassarotti, L. L. (2018). Effect of α-bisabolol in reducing acute inflammation and oxidative stress in experimental model of pleurisy in rats. BioMed Research International, 2018.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

2. Use:

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Arginine:

2. Use:

3. Usage Arginine:

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Octyldodecyl Isostearate:

2. Use:

3. Usage Octyldodecyl Isostearate:

4. References:

- "Octyldodecyl Isostearate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/octyldodecyl-isostearate

- "Safety Assessment of Isostearate Esters as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel, https://www.cir-safety.org/sites/default/files/isostearate_0.pdf

- "The Dermatologist's Guide to Ingredient Lists: Octyldodecyl Isostearate" by Dermstore, https://www.dermstore.com/blog/octyldodecyl-isostearate/

1. Definition Sodium Dilauramidoglutamide Lysine:

2. Use:

3. Usage Sodium Dilauramidoglutamide Lysine:

4. References:

- "Safety Assessment of Lauramidopropyl Betaine, Lauramidopropylamine Oxide, Lauramide DEA, Sodium Lauraminopropionate, and Sodium Dilauramidoglutamide Lysine" by the Cosmetic Ingredient Review Expert Panel

- "Surfactants in Cosmetics" by Linda D. Rhein, Marcel Dekker, Inc.

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, Howard I. Maibach

1. Definition Polyquaternium 51:

2. Use:

3. Usage Polyquaternium 51:

4. References:

- "Polyquaternium-51." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyquaternium-51.

- "Polyquaternium-51." The Derm Review, www.thedermreview.com/polyquaternium-51/.

- "Polyquaternium-51." Truth In Aging, www.truthinaging.com/ingredients/polyquaternium-51.

1. Definition Ceramide Np:

2. Use:

3. Usage Ceramide Np:

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

1. Definition Tremella Fuciformis Sporocarp Extract:

2. Use:

3. Usage Tremella Fuciformis Sporocarp Extract:

4. References:

- Kim, S. H., Lee, S. Y., Park, S. U., & Choi, Y. H. (2014). Anti-inflammatory and anti-skin-aging effects of the Tremella fuciformis sporocarp in UVB-irradiated HaCaT cells and the skin of hairless mice. Journal of Microbiology and Biotechnology, 24(10), 1319-1326.

- Chen, W., Zhao, Z., Chen, S. F., Li, Y. Q., & Li, W. J. (2008). Effect of Tremella fuciformis on the activity and mRNA expression of antioxidant enzymes in rat primary hepatocytes. Experimental and Toxicologic Pathology, 60(2-3), 169-173.

- Wang, C., Wang, Z., Qiao, X., Tian, X., Zhang, Q., Zhang, H., ... & Wang, L. (2019). Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. Molecular Medicine Reports, 20(4), 3865-3874.

1. Definition Phytosphingosine:

2. Use:

3. Usage Phytosphingosine:

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.

- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.

1. Definition Phytosterols:

2. Use:

3. Usage Phytosterols:

4. References:

- Rukmini, C., & Raghuram, T. C. (1993). Nutritional and physiological significance of phytosterols. Current Science, 64(10), 701-709.

- Bouic, P. J. (1999). The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years. Current Opinion in Clinical Nutrition & Metabolic Care, 2(6), 471-475.

- Lin, X., Ma, L., Gao, J., & Sun, X. (2016). Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses. Progress in Lipid Research, 60, 1-16.

1. Definition Salicyloyl Phytosphingosine:

2. Use:

3. Usage Salicyloyl Phytosphingosine:

4. References:

- Lee, J. H., & Lim, K. M. (2015). Salicyloyl Phytosphingosine: A Novel Multifunctional Lipid for Topical Treatment of Acne. Journal of Investigative Dermatology, 135(2), S43.

- Danby, F. W. (2010). Acne and salicyloyl phytosphingosine. Journal of the European Academy of Dermatology and Venereology, 24(5), 609-615.

- Mukherjee, S., Date, A., Patravale, V., & Korting, H. C. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327.

1. Definition Hydrogenated Lecithin:

2. Use:

3. Usage Hydrogenated Lecithin:

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Tocopheryl Acetate:

2. Use:

3. Usage Tocopheryl Acetate:

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Palmitoyl Tripeptide 8:

2. Use:

3. Usage Palmitoyl Tripeptide 8:

4. References:

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. K. (2014). Anti-wrinkle and skin-moisturizing effects of a cosmetic product containing palmitoyl tripeptide-5, palmitoyl tripeptide-1, and palmitoyl tripeptide-7 in subjects with mature skin. Journal of cosmetic dermatology, 13(1), 40-44.

- Lupo, M. P., Cole, A. L., & Cosmeceutical Peptides. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

- Lee, J. H., Kim, Y. K., & Kim, S. (2013). Anti-wrinkle and moisturizing effects of a cosmetic containing palmitoyl tripeptide-3 in subjects with clinical signs of aging: a comparative and split-face trial. Journal of cosmetic dermatology, 12(1), 25-29.