Name: PharmaClinix Lightenex® Gold Cream
Brand: PharmaClinix
Rating: 5 (6 reviews)

Alpha Arbutin

Other Names: Hydroquinone-alpha-D-glucopyranoside; 4-Hydroxyphenyl-alpha-D-glucopyranoside; α-Arbutin

Function: Skin Conditioning, Antioxidant

1. Definition Alpha Arbutin:

Alpha Arbutin is a skin-lightening agent that is derived from the bearberry plant. It is a type of hydroquinone derivative that is commonly used in skincare products to reduce the appearance of dark spots, hyperpigmentation, and melasma.

2. Use:

Alpha Arbutin is primarily used in cosmetics and skincare products for its skin-brightening and lightening properties. It works by inhibiting the enzyme tyrosinase, which is responsible for the production of melanin in the skin. By blocking this enzyme, Alpha Arbutin helps to reduce the production of melanin, leading to a more even skin tone and a reduction in dark spots and hyperpigmentation.

3. Usage Alpha Arbutin:

When using products containing Alpha Arbutin, it is important to follow the instructions provided by the manufacturer. Typically, Alpha Arbutin is used in concentrations ranging from 1-2% in skincare products such as serums, creams, and lotions. It is recommended to apply the product to clean, dry skin once or twice daily, depending on the instructions. It is also important to use sunscreen daily when using products containing Alpha Arbutin, as it can increase the skin's sensitivity to UV radiation.

4. References:

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Boissy, R. E., & Visscher, M. (2006). DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Experimental Dermatology, 15(9), 601–608. https://doi.org/10.1111/j.1600-0625.2006.00449.x

- Smit, N., Vicanova, J., & Pavel, S. (2009). The hunt for natural skin whitening agents. International Journal of Molecular Sciences, 10(12), 5326–5349. https://doi.org/10.3390/ijms10125326

Arbutin

Other Names: Arbutoside; Arbutine

Function: Skin Conditioning, Antioxidant

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

Tetrahexyldecyl Ascorbate

Other Names: VC-IP; Ascorbyl Tetraisopalmitate; Vitamin C Tetraisopalmitate

Function: Skin Conditioning, Antioxidant

1. Definition Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.

3. Usage Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866

- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.

Magnesium Ascorbyl Phosphate

Other Names: MAP; Magnesium L-Ascorbyl-2-phosphate; Ascorbyl phosphate Magnesium

Function: Antioxidant

1. Definition Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is a water-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a stable form of Vitamin C that is less likely to cause irritation compared to other forms of Vitamin C.

2. Use:

Magnesium Ascorbyl Phosphate is used in cosmetics and skincare products for its various benefits on the skin. It helps to protect the skin from free radical damage, reduce the appearance of fine lines and wrinkles, and promote a more even skin tone. Additionally, it can help to boost collagen production and improve the skin's overall texture.

3. Usage Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is typically found in serums, creams, and lotions targeted towards brightening and anti-aging. It is best used in the morning to help protect the skin from environmental stressors throughout the day. To use, apply a small amount of product containing Magnesium Ascorbyl Phosphate onto clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen for added protection.

Precautions: While Magnesium Ascorbyl Phosphate is generally considered safe for most skin types, it is always recommended to do a patch test before using it on the entire face to check for any potential sensitivity or allergic reactions. Additionally, it is important to follow the product instructions and not to exceed the recommended usage to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826–832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

Lactic Acid, L

Function: Skin Conditioning, Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Exfoliant, Skin-Conditioning Agent - Humectant

1. Definition Lactic Acid, L:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is often used in skincare products for its exfoliating and moisturizing properties.

2. Use:

Lactic acid is commonly used in cosmetics and skincare products for its ability to gently exfoliate the skin, promoting cell turnover and revealing smoother, brighter skin. It can also help to improve the skin's texture, reduce the appearance of fine lines and wrinkles, and even out skin tone.

3. Usage Lactic Acid, L:

When using skincare products containing lactic acid, it is important to start with a lower concentration and gradually increase as your skin becomes accustomed to the ingredient. It is recommended to use products containing lactic acid in the evening, as it can increase sensitivity to the sun. It is also important to use sunscreen during the day when using products with lactic acid to protect the skin from sun damage.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327.

Octadecenedioic Acid

Other Names: Mediatone

Function: Emulsifying

1. Definition Octadecenedioic Acid:

Octadecenedioic Acid, also known as Octadec-9-enedioic acid or C18:1 diacid, is a naturally occurring unsaturated fatty acid with a molecular formula C18H32O4. It is commonly used in cosmetics for its skin brightening and anti-aging properties.

2. Use:

Octadecenedioic Acid is used in cosmetics as a skin lightening agent to reduce hyperpigmentation and even out skin tone. It is also known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in anti-aging products. Additionally, it helps to improve the overall texture and appearance of the skin.

3. Usage Octadecenedioic Acid:

Octadecenedioic Acid is typically found in skincare products such as serums, creams, and lotions. It is recommended to use products containing this ingredient as directed by the manufacturer. It is important to perform a patch test before using any new product to check for any potential allergic reactions. As with any skincare ingredient, it is advisable to consult with a dermatologist before incorporating Octadecenedioic Acid into your skincare routine.

4. References:

- Pumori Saokar Telang, Vishal K. Chavhan, Ashwini S. Patil, and Amit A. Telang. "Octadecenedioic acid: A review of its chemistry, pharmacology, and therapeutic potential." Journal of Applied Pharmaceutical Science 7, no. 6 (2017): 241-247.

- J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, A. M. Rios-Romero, and A. E. Marchat. "Octadecenedioic acid inhibits migration and invasion in human lung cancer cells." Biochemical and Biophysical Research Communications 506, no. 1 (2018): 52-59.

- A. E. Marchat, J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, and A. M. Rios-Romero. "Octadecenedioic acid inhibits proliferation and induces apoptosis in human lung cancer cells." Oncology Reports 40, no. 5 (2018): 2859-2867.

Salicylic Acid

Other Names: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

Sodium Hyaluronate

Other Names: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Ascorbyl Palmitate

Other Names: Ascorbyl Pamitate

Function: Masking, Antioxidant

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

Tocopherol

Other Names: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Glycyrrhiza Glabra Extract

Other Names: Glycyrrhiza Glabra Root Extract; Licorice Root Extract; Oil Soluble Licorice (Glycyrrhiza) Extract

Function: Perfuming, Humectant, Skin Conditioning, Antioxidant

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Niacinamid

Ingredient data is being updated. Please check back later.

N-Acetyl Glucosamine

Ingredient data is being updated. Please check back later.

Arctostaphylos Uva Ursi Extract

Ingredient data is being updated. Please check back later.

Ferulic Acid

Function: Preservative, Uv Absorber, Antioxidant, Antimicrobial

1. Definition Ferulic Acid:

Ferulic acid is a powerful antioxidant that is commonly found in plant cell walls, seeds, and leaves. It belongs to a group of compounds known as phenolic acids and is known for its ability to neutralize free radicals and protect the skin from environmental damage.

2. Use:

Ferulic acid is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from UV damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. Ferulic acid is often combined with other antioxidants such as vitamin C and vitamin E to enhance its effectiveness.

3. Usage Ferulic Acid:

When using skincare products containing ferulic acid, it is important to follow the instructions provided by the manufacturer. Typically, ferulic acid can be used in the morning and evening as part of a daily skincare routine. It is recommended to apply a small amount of the product to clean, dry skin and allow it to absorb before applying any other products. It is also important to use sunscreen during the day to protect the skin from further damage.

4. References:

- Tan, B. J., Liu, Y., & Chang, K. L. (2019). Ferulic acid inhibits UVB‐induced matrix metalloproteinases in keratinocytes and extracellular matrix degradation in dermal fibroblasts. Journal of Cellular and Molecular Medicine, 23(1), 547-556.

- Saraf, S., & Mishra, D. (2010). Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition, 48(2), 89-99.

- Zuo, L., Shiah, A., & Roberts, J. (2008). A new approach to enhance the antioxidant capacity of ferulic acid by designing a stable prodrug: a potential oral delivery system for the potent antioxidant. Journal of Medicinal Chemistry, 51(9), 2542-2550.

Retinal

Other Names: Retinaldehyde; Vitamin A aldehyde

Function: Skin Conditioning

1. Definition Retinal:

Retinal, also known as retinaldehyde, is a form of Vitamin A that is commonly used in skincare products for its anti-aging and skin-renewing properties. It is a precursor to retinoic acid, a compound that is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote collagen production.

2. Use:

Retinal is often used in cosmetics to address various skin concerns, including signs of aging, uneven skin tone, and acne. It is a potent ingredient that can help to improve the overall health and appearance of the skin by promoting cell turnover and stimulating collagen production. Retinal is also known for its antioxidant properties, which can help to protect the skin from damage caused by free radicals and environmental stressors.

3. Usage Retinal:

When using skincare products containing retinal, it is important to follow the instructions provided by the manufacturer. Retinal can be a potent ingredient, so it is recommended to start with a lower concentration and gradually increase the frequency of use as tolerated. It is also important to use sunscreen during the day when using retinal, as it can increase the skin's sensitivity to the sun.

Precautions: Some individuals may experience mild irritation or sensitivity when using products containing retinal. It is important to monitor the skin for any signs of irritation and discontinue use if any adverse reactions occur. It is also recommended to consult with a dermatologist before incorporating retinal into your skincare routine, especially if you have sensitive skin or are pregnant.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Draelos, Z. D. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Alpha Arbutin (Skin Conditioning, Antioxidant)	Brightening
1	-	Arbutin (Skin Conditioning, Antioxidant)	Good for dry skin Brightening
1	-	Tetrahexyldecyl Ascorbate (Skin Conditioning, Antioxidant)	Anti Aging Brightening
1	A	Magnesium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
4	B	Lactic Acid, L (Skin Conditioning, Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Exfoliant, Skin-Conditioning Agent - Humectant)	Anti Aging Bad for sensitive skin
1	-	Octadecenedioic Acid (Emulsifying)	Cleansing
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Ascorbyl Palmitate (Masking, Antioxidant)	Fungal Acne Trigger
1	-	Tocopherol	Good for dry skin Anti Aging
5	-	Glycyrrhiza Glabra Extract (Perfuming, Humectant, Skin Conditioning, Antioxidant)	Brightening Acne fighting
-	-	Niacinamid
-	-	N-Acetyl Glucosamine
-	-	Arctostaphylos Uva Ursi Extract
1 2	-	Ferulic Acid (Preservative, Uv Absorber, Antioxidant, Antimicrobial)	Anti Aging
5 6	-	Retinal (Skin Conditioning)

PharmaClinix Lightenex® Gold Cream

Ingredients

Analysis results of Ingredients

Ingredient List