Province Apothecary Clear Skin Advanced Face Serum

1. Definition Centella Asiatica (Gotu Kola):

Centella Asiatica, also known as Gotu Kola, is a small, herbaceous plant native to Asia and India. It has been used for centuries in traditional medicine for its healing properties and is now gaining popularity in the cosmetic industry for its skin-soothing and anti-aging benefits.

2. Use:

Centella Asiatica is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce inflammation. It is also known for its antioxidant properties, which help protect the skin from environmental stressors and free radicals. Additionally, Centella Asiatica is believed to help with wound healing and scar reduction, making it a popular ingredient in products targeted towards acne-prone or sensitive skin.

3. Usage Centella Asiatica (Gotu Kola):

Centella Asiatica can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. When using products containing Centella Asiatica, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or pre-existing skin conditions.

4. References:

- Bylka, W., Znajdek-Awizenz, P., Studzińska-Sroka, E., Brzezińska, M. (2014). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii, 31(1), 46-49.

- Shukla, A., Rasik, A. M., & Dhawan, B. N. (1999). Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotherapy Research, 13(1), 50-54.

- Kim, S. R., Jung, Y. J., Kim, D. H., & An, H. J. (2014). The effects of Centella asiatica on antioxidant status and resistance to oxidative stress in human hepatoma cells. Journal of Ethnopharmacology, 151(1), 131-139.

1. Definition Camellia Sinensis (Green Tea) Leaf:

Camellia Sinensis (Green Tea) Leaf is a plant extract derived from the leaves of the Camellia Sinensis plant, which is commonly used to produce green tea. It is rich in antioxidants, polyphenols, and vitamins, making it a popular ingredient in cosmetics for its anti-aging and skin-soothing properties.

2. Use:

Green tea leaf extract is commonly used in skincare products such as serums, creams, and masks due to its antioxidant properties. It helps to protect the skin from free radicals, reduce inflammation, and promote overall skin health. Green tea leaf extract is also known for its ability to improve the appearance of pores, reduce redness, and provide a calming effect on the skin.

3. Usage Camellia Sinensis (Green Tea) Leaf:

When using cosmetics containing Camellia Sinensis (Green Tea) Leaf extract, it is important to patch test the product first to ensure that it does not cause any irritation or allergic reactions. It is recommended to follow the instructions provided on the product packaging and to use the product as directed. Green tea leaf extract can be used in both morning and evening skincare routines, and can be applied to the face, neck, and décolletage.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Lin, Y., Shi, R., Wang, X., Shen, H. M. (2018). Luteolin, a flavonoid with potential for cancer prevention and therapy. Current Cancer Drug Targets, 18(7), 629-646.

- Nam, J. H., Moon, T. C., Kang, J. Y., Kim, C. H., Kim, H. M., Jeong, H. J. (2017). Evaluation of the anti-inflammatory effects of green tea extract on Porphyromonas gingivalis lipopolysaccharide-treated macrophages and a human keratinocyte cell line. Journal of Periodontal & Implant Science, 47(3), 144-159.

1. Definition Urtica Dioica (Nettle) Leaf:

Urtica Dioica, commonly known as Nettle Leaf, is a plant that has been used for centuries for its medicinal properties. It is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in cosmetics.

2. Use:

Nettle Leaf is often used in cosmetics for its anti-inflammatory and antioxidant properties. It can help soothe irritated skin, reduce redness, and improve overall skin health. Nettle Leaf is also known for its astringent properties, making it beneficial for oily or acne-prone skin.

3. Usage Urtica Dioica (Nettle) Leaf:

Nettle Leaf can be found in various cosmetic products such as creams, serums, masks, and lotions. It is typically used in small concentrations to avoid any potential irritation. Nettle Leaf can be applied directly to the skin or used in combination with other ingredients to enhance its benefits.

Precautions: While Nettle Leaf is generally considered safe for topical use, it is important to perform a patch test before using it on the skin to check for any allergic reactions. Pregnant or breastfeeding women should consult with a healthcare provider before using products containing Nettle Leaf.

4. References:

- Sharma, N., Sharma, V., & Sharma, R. (2012). Urtica dioica (Stinging Nettle): A Review. International Research Journal of Pharmacy, 3(7), 24-28.

- Dweck, A. C. (2016). Nettles in cosmetics. Personal Care Magazine, 13(3), 33-36.

- Basch, E., Ulbricht, C., Hammerness, P., Bevins, A., Sollars, D., & Tanguay-Colucci, S. (2003). Nettle (Urtica dioica): A Review of its Uses and Health Benefits. Pharmacy World & Science, 25(3), 114-126.

1. Definition Rosa Rubiginosa Seed Oil:

Rosa Rubiginosa Seed Oil, also known as Rosehip Seed Oil, is a natural oil extracted from the seeds of the Rosa rubiginosa plant, which is native to certain regions of South America. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Rosa Rubiginosa Seed Oil is commonly used in cosmetics for its hydrating, anti-inflammatory, and regenerative properties. It is known to help improve skin elasticity, reduce the appearance of scars and wrinkles, and promote overall skin health. Additionally, it can help protect the skin from environmental damage and soothe irritation.

3. Usage Rosa Rubiginosa Seed Oil:

Rosa Rubiginosa Seed Oil can be used in various skincare products, such as serums, moisturizers, and facial oils. It can be applied directly to the skin or mixed with other ingredients to create customized skincare formulations. It is suitable for all skin types, including sensitive and acne-prone skin, but it is recommended to do a patch test before using it on the face to ensure compatibility.

4. References:

- Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. 2017;19(1):70. Published 2017 Dec 27. doi:10.3390/ijms19010070

- Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-1856. Published 2015 Nov 19. doi:10.2147/CIA.S90092

- Gutiérrez-Pajares JL, Juárez-Vázquez Mdel C, Luna-López A, et al. Effect of rose hip (Rosa rubiginosa) extraction process on oil and defatted meal physicochemical and functional properties. Plant Foods Hum Nutr. 2015;70(4):450-456. doi:10.1007/s11130-015-0501-1

1. Definition Rubus Idaeus (Raspberry) Seed Oil:

Rubus Idaeus (Raspberry) Seed Oil is a natural oil extracted from the seeds of the raspberry fruit. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare products.

2. Use:

Raspberry Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve elasticity, and protect against environmental damage. It is suitable for all skin types, including sensitive and acne-prone skin.

3. Usage Rubus Idaeus (Raspberry) Seed Oil:

Raspberry Seed Oil can be used in various skincare products, such as moisturizers, serums, and facial oils. It can be applied directly to the skin or mixed with other oils or creams. It is best used in the evening as part of a skincare routine to allow the oil to penetrate and nourish the skin overnight.

Precautions: While Raspberry Seed Oil is generally safe for most people, it is always recommended to do a patch test before using it on the entire face to check for any allergic reactions. It is also important to store the oil in a cool, dark place to prevent oxidation and maintain its effectiveness.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

- Kamal, R., & El-Sayed, S. (2015). Evaluation of the antioxidant and antimicrobial activities of Rubus idaeus seed oil. Journal of Applied Pharmaceutical Science, 5(8), 064-070.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143.

1. Definition Hippophae Rhamnoides (Sea Buckthorn) Oil:

Sea Buckthorn oil is derived from the berries of the Hippophae Rhamnoides plant, which is native to the Himalayas. It is rich in vitamins, minerals, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Sea Buckthorn oil is known for its nourishing and moisturizing properties, making it a great ingredient for skincare products. It is often used in anti-aging products due to its ability to promote skin elasticity and reduce the appearance of wrinkles. It also has anti-inflammatory properties, which can help soothe irritated skin and reduce redness.

3. Usage Hippophae Rhamnoides (Sea Buckthorn) Oil:

Sea Buckthorn oil can be used in a variety of ways in skincare products. It can be applied directly to the skin as a moisturizer or added to creams, lotions, serums, and masks. It is suitable for all skin types, including sensitive skin, but it is always recommended to do a patch test before using it on a larger area of the skin to ensure there are no adverse reactions.

Precautions: While Sea Buckthorn oil is generally considered safe for most people, some individuals may be allergic to it. It is always recommended to consult with a dermatologist before incorporating any new skincare product into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, S. et al. (2018). Anti-inflammatory effects of Hippophae rhamnoides L. extract on human eosinophils and mast cells. Journal of Ethnopharmacology, 212, 256-261.

- Yang, B. et al. (2018). Sea buckthorn (Hippophae rhamnoides L.) oil protects against chronic stress-induced inhibitory function of natural killer cells in rats. International Immunopharmacology, 54, 315-321.

- Zhang, Y. et al. (2019). Protective effects of sea buckthorn (Hippophae rhamnoides L.) seed oil against carbon tetrachloride-induced hepatotoxicity in mice. Food and Chemical Toxicology, 123, 491-498.

1. Definition Tocopherol (Vitamin E):

Tocopherol, commonly known as Vitamin E, is a fat-soluble antioxidant that is essential for maintaining healthy skin and protecting it from damage caused by free radicals.

2. Use:

Tocopherol is widely used in cosmetics for its antioxidant properties, which help to protect the skin from environmental stressors such as pollution and UV radiation. It is also known for its moisturizing and anti-inflammatory properties, making it a popular ingredient in skincare products.

3. Usage Tocopherol (Vitamin E):

Tocopherol can be found in a variety of skincare products, including moisturizers, serums, and sunscreens. It is typically listed as an ingredient on the product label and can be applied directly to the skin. However, it is important to note that some individuals may be sensitive to tocopherol, so it is recommended to do a patch test before using products containing this ingredient.

4. References:

- Lin, F.-H., Lin, J.-Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., … & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Thiele, J. J., Hsieh, S. N., Briviba, K., Sies, H. (1999). Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. Journal of Investigative Dermatology, 113(3), 335-339.

- Nachbar, F., Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of Molecular Medicine, 73(1), 7-17.

1. Definition Curcuma Longa (Turmeric) Root Oil:

Curcuma Longa (Turmeric) Root Oil is a natural essential oil extracted from the roots of the Curcuma Longa plant, also known as Turmeric. It is known for its vibrant yellow color and distinct earthy aroma.

2. Use:

Turmeric Root Oil is commonly used in cosmetics for its anti-inflammatory, antioxidant, and antibacterial properties. It is often included in skincare products for its ability to brighten skin, reduce acne and blemishes, and improve overall skin health. It is also used in hair care products to promote hair growth, strengthen hair follicles, and add shine to the hair.

3. Usage Curcuma Longa (Turmeric) Root Oil:

Turmeric Root Oil should be used in moderation as it is a potent essential oil. It can be diluted with a carrier oil such as coconut oil or jojoba oil before applying to the skin or hair. It is recommended to perform a patch test before using Turmeric Root Oil to check for any allergic reactions. It should be stored in a cool, dark place away from direct sunlight to preserve its potency.

4. References:

- Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243-1264.

- Hewlings, S. J., & Kalman, D. S. (2017). Curcumin: A Review of Its’ Effects on Human Health. Foods, 6(10), 92.

- Prasad, S., & Aggarwal, B. B. (2011). Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine. In Herbal Medicine: Biomolecular and Clinical Aspects (2nd ed.). CRC Press/Taylor & Francis.

1. Definition Boswellia Carterii Oil:

Boswellia Carterii Oil, also known as Frankincense Oil, is a natural essential oil derived from the resin of the Boswellia Carterii tree. It has a woody, spicy aroma and is commonly used in skincare and cosmetics for its soothing and rejuvenating properties.

2. Use:

Boswellia Carterii Oil is used in cosmetics for its anti-inflammatory, anti-aging, and skin-healing properties. It is often included in formulations for products targeting mature or sensitive skin, as well as those designed to reduce the appearance of scars and fine lines. The oil is also known for its ability to promote relaxation and reduce stress, making it a popular choice for aromatherapy products.

3. Usage Boswellia Carterii Oil:

When using Boswellia Carterii Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to do a patch test before using it on larger areas of the skin to check for any allergic reactions. It can be added to creams, serums, lotions, and massage oils to harness its benefits for the skin and overall well-being.

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Shah, G., Shri, R., Panchal, V., Sharma, N., Singh, B., & Mann, A. S. (2011). Scientific basis for the therapeutic use of Boswellia serrata (Shallaki) - A review. Indian Journal of Traditional Knowledge, 10(4), 699-705.

- Al-Yasiry, A. R. M., & Kiczorowska, B. (2016). Frankincense - therapeutic properties. Advances in Hygiene & Experimental Medicine, 70, 380-391.

1. Definition Helichrysum Italicum (Everlasting) Oil:

Helichrysum Italicum (Everlasting) Oil is a natural essential oil derived from the flowers of the Helichrysum Italicum plant, also known as Immortelle or Everlasting. It is highly prized in the cosmetic industry for its anti-inflammatory, antioxidant, and regenerative properties.

2. Use:

Helichrysum Italicum Oil is commonly used in skincare products for its ability to promote skin healing, reduce inflammation, and improve overall skin health. It is often included in formulations for mature skin, as it can help to reduce the appearance of fine lines and wrinkles, as well as promote a more youthful complexion.

3. Usage Helichrysum Italicum (Everlasting) Oil:

When using Helichrysum Italicum Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to use a carrier oil, such as jojoba or coconut oil, to dilute the Helichrysum Oil before applying it to the skin. It is also important to perform a patch test before using the oil on a larger area of skin, as some individuals may be sensitive to essential oils.

4. References:

- Tundis, R., Loizzo, M. R., & Menichini, F. (2014). Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update. Mini reviews in medicinal chemistry, 10(4), 315-331.

- Garg, A., Garg, S., Zaneveld, L. J. D., & Singla, A. K. (2001). Chemistry and pharmacology of the Citrus bioflavonoid hesperidin. Phytotherapy Research, 15(8), 655-669.

- Kaur, G., & Kaur, R. (2015). Helichrysum italicum: A comprehensive review on its traditional uses, phytochemistry, pharmacological activities, and safety profile. Arabian Journal of Chemistry, 8(5), 662-673.