QRxLabs Glycolic Acid 10% Wrinkle Control Pads

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Vegetable Glycerin:

Vegetable Glycerin, also known as glycerol, is a clear, odorless liquid derived from plant oils such as coconut, palm, or soy. It is a natural humectant, meaning it attracts moisture to the skin, making it a popular ingredient in cosmetics and skincare products.

2. Use:

Vegetable Glycerin is commonly used in cosmetics as a moisturizer and emollient. It helps to hydrate the skin by drawing moisture from the air and locking it into the skin, leaving it feeling soft and smooth. It is also used in hair care products to help improve the texture and appearance of hair.

3. Usage Vegetable Glycerin:

Vegetable Glycerin can be found in a variety of cosmetic products such as lotions, creams, serums, and hair conditioners. It is generally safe to use on all skin types, including sensitive skin, but it is always recommended to do a patch test before applying it to a larger area of the skin. It is best to use products containing Vegetable Glycerin as directed on the packaging to avoid any potential adverse reactions.

4. References:

- Sharma, R., & Mahajan, V. K. (2018). Role of humectants in cosmetic products. Indian Dermatology Online Journal, 9(4), 244–249. https://doi.org/10.4103/idoj.IDOJ_265_17

- Draelos, Z. D. (2018). Cosmetic Formulation of Skin Care Products. In Cosmeceuticals, 3rd Edition (pp. 25-43). Elsevier. https://doi.org/10.1016/B978-0-12-802005-1.00003-7

- Burdock, G. A. (2005). Encyclopedia of Food and Color Additives (Vol. 1). CRC Press.

1. Definition Vitamin B5:

Vitamin B5, also known as pantothenic acid, is a water-soluble vitamin that is essential for the synthesis of coenzyme A, which plays a crucial role in various metabolic processes in the body. It is commonly found in foods such as meat, eggs, dairy products, and vegetables.

2. Use:

Vitamin B5 is widely used in cosmetics for its moisturizing and skin-healing properties. It helps to improve skin hydration, reduce inflammation, and promote wound healing. It is often included in skincare products such as moisturizers, serums, and creams to help maintain healthy skin.

3. Usage Vitamin B5:

When using Vitamin B5 in cosmetics, it is important to follow the recommended dosage to avoid any potential side effects. It is generally considered safe for topical use, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Vitamin B5 to ensure compatibility with your skin.

4. References:

- Draelos, Zoe Diana. "Cosmetic Formulation of Skin Care Products." John Wiley & Sons, 2015.

- Baumann, Leslie. "Cosmetic Dermatology: Principles and Practice." McGraw-Hill Education, 2009.

- Fiume, Monice M. et al. "Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics." International Journal of Toxicology, vol. 26, no. 2, 2007, pp. 63-88.

1. Definition Camellia Sinensis (Green Tea) Extract:

Camellia Sinensis (Green Tea) Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green tea. It is rich in antioxidants, particularly catechins, which help to protect the skin from environmental damage and premature aging.

2. Use:

Green tea extract is commonly used in cosmetics for its antioxidant properties, which can help to reduce inflammation, protect against UV damage, and improve overall skin health. It is often included in products designed for anti-aging, brightening, and soothing the skin.

3. Usage Camellia Sinensis (Green Tea) Extract:

Green tea extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and cleansers. It is typically applied topically to the skin, either on its own or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using a new product containing green tea extract to check for any potential allergic reactions.

4. References:

- Yoon HS, Kim JR, Park GY, Kim JY, Won YJ, Kim HR, Kim BJ. Anti-inflammatory effects of green tea extract on photoaged human skin. J Dermatol Sci. 2016 Oct;84(1):74-83. doi: 10.1016/j.jdermsci.2016.06.016. Epub 2016 Jul 1. PMID: 27422719.

- Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. doi: 10.1097/00042728-200507000-00011. PMID: 16029678.

- Zhou B, Wu LM, Yang L, Liu ZL. Evidence for alpha-bisabolol as a natural antioxidant. J Agric Food Chem. 2007 Aug 8;55(16):6302-6306. doi: 10.1021/jf070477y. Epub 2007 Jul 11. PMID: 17625876.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Menthol:

Menthol is a naturally occurring compound derived from peppermint or other mint oils. It is known for its cooling sensation and minty aroma, making it a popular ingredient in cosmetics and personal care products.

2. Use:

Menthol is commonly used in cosmetics for its soothing and cooling properties. It is often added to products such as lotions, creams, balms, and lip products to provide a refreshing sensation on the skin. Menthol can also help to relieve minor skin irritations and itching.

3. Usage Menthol:

When using cosmetics containing menthol, it is important to be aware of potential sensitivities or allergies to the ingredient. Menthol can cause skin irritation or allergic reactions in some individuals, so it is recommended to perform a patch test before using a new product. Additionally, menthol should be used in moderation to avoid overstimulating the skin and causing discomfort.

4. References:

- Yosipovitch, G., & Maibach, H. I. (1998). Sensitive Skin Syndrome. CRC Press.

- Rawlings, A. V., & Leyden, J. J. (2004). Skin Moisturization. CRC Press.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. John Wiley & Sons.

1. Definition Eucalyptus (Eucalyptus Grandis) Oil:

Eucalyptus (Eucalyptus Grandis) Oil is a natural essential oil extracted from the leaves of the Eucalyptus Grandis tree. It is known for its refreshing and invigorating scent, as well as its antibacterial and anti-inflammatory properties.

2. Use:

Eucalyptus Oil is commonly used in cosmetics for its aromatic qualities and skincare benefits. It can be found in a variety of products such as creams, lotions, soaps, and shampoos. Its cooling sensation makes it a popular ingredient in products designed to soothe muscle aches and pains.

3. Usage Eucalyptus (Eucalyptus Grandis) Oil:

When using Eucalyptus Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin in its concentrated form. It is recommended to perform a patch test before using any products containing Eucalyptus Oil to check for any allergic reactions. Avoid using Eucalyptus Oil near the eyes or on broken skin, and discontinue use if any irritation occurs.

4. References:

- Silva, J., Abebe, W., Sousa, S. M., Duarte, V. G., Machado, M. I., & Matos, F. J. (2003). Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. Journal of ethnopharmacology, 89(2-3), 277-283.

- Juergens, U. R., Dethlefsen, U., Steinkamp, G., Gillissen, A., Repges, R., & Vetter, H. (2003). Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial. Respiratory medicine, 97(3), 250-256.

- Sadlon, A. E., & Lamson, D. W. (2010). Immune-modifying and antimicrobial effects of Eucalyptus oil and simple inhalation devices. Alternative medicine review, 15(1), 33-47.

1. Definition Mentha Spicata (Spearmint) Oil:

Mentha Spicata (Spearmint) Oil is a natural essential oil derived from the steam distillation of the leaves of the spearmint plant. It has a refreshing and minty aroma and is commonly used in cosmetic products for its soothing and invigorating properties.

2. Use:

Spearmint oil is often used in cosmetics for its cooling and calming effects on the skin. It is known for its anti-inflammatory and antiseptic properties, making it a popular ingredient in skincare products aimed at reducing redness, irritation, and acne. Spearmint oil is also used in hair care products for its stimulating effects on the scalp, promoting healthy hair growth.

3. Usage Mentha Spicata (Spearmint) Oil:

Spearmint oil should be used in cosmetics in small concentrations to avoid skin irritation or sensitization. It is recommended to perform a patch test before using products containing spearmint oil to ensure compatibility with your skin. Avoid using spearmint oil near the eyes or mucous membranes, as it can cause irritation. Pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products containing spearmint oil.

4. References:

- Kaur, G., & Athar, M. (2008). Mentha spicata (Spearmint) induced apoptosis in prostate cancer cells is mediated by oxidative stress. Food and Chemical Toxicology, 46(12), 3651-3658.

- Silva, J., Abebe, W., & Sousa, S. M. (2003). Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. Journal of Ethnopharmacology, 89(2-3), 277-283.

- Sienkiewicz, M., Łysakowska, M., & Denys, P. (2012). The antimicrobial activity of thyme essential oil against multidrug resistant clinical bacterial strains. Natural Product Communications, 7(1), 1934578X1200700128.

1. Definition Vitamin E:

Vitamin E is a fat-soluble antioxidant that helps protect skin cells from damage caused by free radicals and UV radiation. It is commonly used in cosmetics for its moisturizing and anti-aging properties.

2. Use:

Vitamin E is often included in skincare products such as creams, lotions, and serums to help hydrate and nourish the skin. It is also used in hair care products to promote healthy hair growth and prevent split ends. In addition, Vitamin E can help improve the appearance of scars and stretch marks by promoting skin regeneration.

3. Usage Vitamin E:

When using Vitamin E in cosmetics, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to do a patch test before using Vitamin E products on a larger area of the skin. Additionally, Vitamin E should be stored in a cool, dark place to prevent oxidation and maintain its efficacy.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Farris, P. K. (2007). Cosmeceuticals and Cosmetic Practice. Hoboken, NJ: Wiley-Blackwell.

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. Boca Raton, FL: CRC Press.

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

1. Definition Diazolidinyl Urea:

Diazolidinyl Urea is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde to inhibit microbial growth.

2. Use:

Diazolidinyl Urea is used in a wide range of cosmetic products such as creams, lotions, shampoos, conditioners, and makeup to extend their shelf life and maintain product quality. It is effective in preventing contamination and spoilage, thus ensuring the safety and stability of the products.

3. Usage Diazolidinyl Urea:

When using products containing Diazolidinyl Urea, it is important to follow the recommended usage guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 0.5%, depending on the formulation and intended use of the product. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this preservative.

4. References:

- Cosmetic Ingredient Review (CIR). (2006). Final Report on the Safety Assessment of Diazolidinyl Urea. Retrieved from https://www.cir-safety.org/sites/default/files/diazolidinyl%20urea.pdf

- Personal Care Council. (2019). Diazolidinyl Urea. Retrieved from https://www.personalcarecouncil.org/ingredient-info/diazolidinyl-urea/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.10