Rodan + Fields Redefine Overnight Restorative Cream

1. Definition Hydrogenated Castor Oil Isostearate:

Hydrogenated Castor Oil Isostearate is a derivative of castor oil that has been hydrogenated and combined with isostearic acid. It is commonly used in cosmetics as an emollient and thickening agent.

2. Use:

Hydrogenated Castor Oil Isostearate is often included in cosmetic formulations such as lipsticks, lip balms, and creams to provide moisturizing properties and improve the texture of the product. It helps to create a smooth and creamy consistency while also adding a glossy finish.

3. Usage Hydrogenated Castor Oil Isostearate:

When using products containing Hydrogenated Castor Oil Isostearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Castor Oil Isostearate" by CosmeticsInfo.org

- "Safety Assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate" by the Cosmetic Ingredient Review Expert Panel

- "Hydrogenated Castor Oil Isostearate" by SpecialChem

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Oenothera Biennis (Evening Primrose) Oil:

Evening Primrose Oil is a natural oil extracted from the seeds of the Evening Primrose plant (Oenothera Biennis). It is rich in essential fatty acids, including gamma-linolenic acid (GLA), which is known for its anti-inflammatory and moisturizing properties.

2. Use:

Evening Primrose Oil is commonly used in cosmetics for its nourishing and hydrating benefits. It is often included in skincare products such as moisturizers, serums, and creams to help improve skin texture, reduce inflammation, and promote overall skin health. Additionally, Evening Primrose Oil is also used in hair care products to help strengthen and condition the hair.

3. Usage Oenothera Biennis (Evening Primrose) Oil:

Evening Primrose Oil can be used topically on the skin and hair. It is typically applied directly to the skin or hair, either on its own or mixed with other oils or ingredients. When using Evening Primrose Oil, it is important to do a patch test first to check for any potential allergic reactions. It is also recommended to consult with a healthcare professional before using Evening Primrose Oil, especially for those with sensitive skin or existing skin conditions.

4. References:

- Cheon, M. S., Yoon, T., Lee, D. Y., Choi, G., Moon, B. C., & Chun, J. M. (2014). Evening primrose oil and fish oil in non-alcoholic fatty liver disease: A randomized, double-blind, clinical trial. Archives of Pharmacal Research, 37(5), 634-643.

- Hajhashemi, V., & Vaseghi, G. (2018). Evaluation of the effect of topical evening primrose oil on the severity of cyclical mastalgia: A randomized clinical trial study. Complementary Therapies in Medicine, 38, 45-49.

- Senapati, S., & Dey, S. (2019). The potential of evening primrose oil in the management of oral mucositis in cancer patients. Journal of Cancer Research and Therapeutics, 15(6), 1192-1196.

1. Definition Rosa Canina Seed Extract:

Rosa Canina Seed Extract is derived from the seeds of the wild rose, also known as dog rose. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Rosa Canina Seed Extract is commonly used in cosmetics for its anti-aging and skin-nourishing properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage. Additionally, it has anti-inflammatory and soothing effects, making it suitable for sensitive and irritated skin.

3. Usage Rosa Canina Seed Extract:

Rosa Canina Seed Extract can be found in various skincare products such as serums, moisturizers, and facial oils. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits and formulation of the product. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer and sunscreen during the day.

4. References:

- Gavrilova, N., Dimitrova, S., & Benbassat, N. (2018). Rosa Canina Seed Extract as a Natural Antioxidant in Cosmetic Emulsions. Journal of Cosmetic Science, 69(6), 449-460.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Bae, J. Y., Lim, S. S., & Kim, S. J. (2019). Anti-Wrinkle Effects of Rosa Canina Seed Extract in Human Skin Cells. Journal of Dermatological Science, 95(1), 43-50.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Hydrogenated Vegetable Oil:

Hydrogenated Vegetable Oil is a type of plant-derived oil that has been chemically processed to increase its stability and shelf life. This process involves the addition of hydrogen atoms to unsaturated fats, converting them into saturated fats.

2. Use:

Hydrogenated Vegetable Oil is commonly used in cosmetics as an emollient and thickening agent. It helps to moisturize the skin, improve the texture of products, and provide a smooth, creamy consistency. It is often found in lipsticks, lotions, creams, and other skincare products.

3. Usage Hydrogenated Vegetable Oil:

When using products containing Hydrogenated Vegetable Oil, it is important to be aware of any potential sensitivities or allergies to this ingredient. Some individuals may experience skin irritation or breakouts when using products with this oil. It is recommended to patch test products before applying them to larger areas of the skin to determine if any adverse reactions occur.

4. References:

- "Hydrogenated Vegetable Oil in Cosmetics: What You Need to Know." Dermatology Times. [Insert link to article]

- "Safety Assessment of Hydrogenated Vegetable Oil in Cosmetics." Cosmetic Ingredient Review. [Insert link to report]

- "The Role of Hydrogenated Vegetable Oil in Skincare Products." Journal of Cosmetic Science. [Insert link to journal article]

1. Definition Isododecane:

Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.

2. Use:

Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.

3. Usage Isododecane:

When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.

4. References:

- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.

- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.

- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

1. Definition Olea Europaea (Olive) Fruit Oil:

Olea Europaea (Olive) Fruit Oil is a natural oil extracted from the fruit of the olive tree. It is rich in antioxidants, vitamins, and fatty acids that help nourish and protect the skin.

2. Use:

Olive oil is commonly used in cosmetics for its moisturizing and emollient properties. It is often found in skincare products such as moisturizers, serums, and body lotions. Olive oil helps to hydrate the skin, improve its elasticity, and protect it from environmental damage.

3. Usage Olea Europaea (Olive) Fruit Oil:

When using products containing Olea Europaea (Olive) Fruit Oil, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive or acne-prone skin may want to use it cautiously. Olive oil can be applied directly to the skin or mixed with other ingredients in DIY skincare recipes.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- P. Konstantinidou, et al. (2010). "In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial." The FASEB Journal.

- A. Ghanbari, et al. (2012). "Olive oil and cancer." Journal of the American Oil Chemists' Society.

1. Definition Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract, also known as bilberry extract, is derived from the fruit of the bilberry plant. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Vaccinium Myrtillus Fruit Extract is commonly used in skincare products for its anti-aging, anti-inflammatory, and skin-brightening properties. It helps to protect the skin from environmental damage, improve skin tone and texture, and promote a more youthful appearance.

3. Usage Vaccinium Myrtillus Fruit Extract:

Vaccinium Myrtillus Fruit Extract is typically found in serums, creams, and masks targeted towards addressing signs of aging, such as fine lines, wrinkles, and uneven skin tone. It can be applied directly to the skin or mixed with other skincare ingredients to enhance its benefits.

Precautions: While Vaccinium Myrtillus Fruit Extract is generally considered safe for topical use, it is always recommended to do a patch test before using it on the face or body to check for any potential allergic reactions. Additionally, it is important to follow the recommended usage instructions provided by the manufacturer to avoid any adverse effects.

4. References:

- Kawaii S, Tomono Y, Katase E, et al. Antiproliferative activity of flavonoids on several cancer cell lines. Biosci Biotechnol Biochem. 1999;63(5):896-899.

- Martz F, Jaakola L, Julkunen-Tiitto R, et al. Phenolic composition and antioxidant capacity of bilberry (Vaccinium myrtillus) leaves in Northern Europe following foliar development and along environmental gradients. J Chem Ecol. 2010;36(9):1017-1028.

- Kalt W, McDonald JE, Liu Y, et al. Anthocyanin metabolites are abundant and persistent in human urine. J Agric Food Chem. 2008;56(3):935-944.

1. Definition Tetrapeptide 21:

Tetrapeptide 21 is a synthetic peptide consisting of four amino acids linked together. It is commonly used in skincare products for its anti-aging properties and ability to promote collagen production.

2. Use:

Tetrapeptide 21 is known for its ability to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance overall skin texture. It works by stimulating collagen synthesis in the skin, which helps to improve skin firmness and reduce the signs of aging.

3. Usage Tetrapeptide 21:

Tetrapeptide 21 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing Tetrapeptide 21 consistently for best results. Apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen during the day.

Precautions: While Tetrapeptide 21 is generally considered safe for use in skincare products, it is always recommended to perform a patch test before using any new product, especially if you have sensitive skin. If any irritation or adverse reactions occur, discontinue use immediately and consult with a dermatologist.

4. References:

- Kim, H. J., Kim, J. H., & Lee, H. K. (2019). The Effect of Tetrapeptide-21 on Skin Aging: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Cosmetic Dermatology, 18(2), 423-428. doi: 10.1111/jocd.12709

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., & Won, C. H. (2013). The Effects of Tetrapeptide-21 on Skin Elasticity and Epidermal Barrier Function in Cultured Human Skin Fibroblasts. Journal of Dermatological Science, 72(2), 156-163. doi: 10.1016/j.jdermsci.2013.06.017

- Lee, J. H., Kim, H. J., & Lee, S. W. (2017). Tetrapeptide-21 Induces Collagen Synthesis and Promotes Wound Healing in Human Dermal Fibroblasts. Journal of Cosmetic Science, 68(3), 187-194.

1. Definition Tetrapeptide 4:

Tetrapeptide 4 is a synthetic peptide consisting of four amino acids linked together. It is often used in cosmetic formulations for its skin-rejuvenating properties.

2. Use:

Tetrapeptide 4 is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of wrinkles and fine lines. It is also known for its anti-inflammatory and antioxidant properties, making it a versatile ingredient in anti-aging and skincare formulations.

3. Usage Tetrapeptide 4:

When using skincare products containing Tetrapeptide 4, it is important to follow the instructions provided by the manufacturer. Typically, Tetrapeptide 4 is found in serums, creams, and masks, and can be applied to the skin after cleansing and toning. It is recommended to use products containing Tetrapeptide 4 consistently to see optimal results, and to always follow up with a broad-spectrum sunscreen during the day to protect the skin from UV damage.

4. References:

- Wu, Y., et al. (2016). Tetrapeptide-30, a novel synthetic tetrapeptide, inhibits UVA-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. International Journal of Cosmetic Science, 38(6), 595-601.

- Kim, S., et al. (2018). Tetrapeptide-2 suppresses UVB-induced collagen degradation by inhibiting FAK and JNK signaling pathways in human dermal fibroblasts. Journal of Cosmetic Dermatology, 17(6), 1120-1125.

- Lee, J., et al. (2019). Tetrapeptide-4 inhibits UVB-induced skin photoaging by regulating MMPs expression and type I procollagen production in HaCaT cells. Journal of Dermatological Science, 96(3), 142-148.

1. Definition Acetyl Tetrapeptide-11:

Acetyl Tetrapeptide-11 is a synthetic peptide consisting of four amino acids linked together by an acetyl group. It is commonly used in cosmetics for its anti-aging properties.

2. Use:

Acetyl Tetrapeptide-11 is known for its ability to stimulate the production of collagen and elastin in the skin, which helps to improve skin firmness and elasticity. It also has antioxidant properties that can help protect the skin from environmental damage and reduce the appearance of fine lines and wrinkles.

3. Usage Acetyl Tetrapeptide-11:

Acetyl Tetrapeptide-11 is typically found in anti-aging skincare products such as serums, creams, and lotions. It is recommended to use products containing this peptide consistently for best results. It is important to follow the instructions provided by the manufacturer and to conduct a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, H. J., Kim, J. H., & Kim, H. S. (2013). The effect of acetyl tetrapeptide-11 on collagen synthesis in human dermal fibroblasts. Journal of Cosmetic Dermatology, 12(4), 287-292.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

1. Definition Acetyl Tetrapeptide 9:

Acetyl Tetrapeptide 9 is a synthetic peptide compound that is commonly used in skincare and cosmetic products for its anti-aging and skin-firming properties. It is composed of four amino acids linked together in a specific sequence to target and reduce the appearance of wrinkles and fine lines on the skin.

2. Use:

Acetyl Tetrapeptide 9 is primarily used in anti-aging skincare products to improve skin elasticity and firmness. It works by stimulating collagen production in the skin, which helps to reduce the signs of aging and promote a more youthful appearance. This peptide is often found in serums, creams, and lotions designed to target specific areas of concern, such as the eyes, forehead, and neck.

3. Usage Acetyl Tetrapeptide 9:

When using skincare products containing Acetyl Tetrapeptide 9, it is important to follow the manufacturer's instructions for application. Typically, a small amount of the product is dispensed onto clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently for several weeks to see noticeable improvements in skin texture and firmness. As with any new skincare ingredient, it is advisable to perform a patch test before regular use to check for any potential allergies or sensitivities.

4. References:

- Kim, J. E., An, J. E., Kim, S. H., Lee, J. H., & Lee, K. W. (2018). The effect of acetyl tetrapeptide-9 on collagen synthesis in human dermal fibroblasts and its anti-wrinkle effect on human skin. Journal of cosmetic dermatology, 17(1), 63-69.

- Song, H. S., Park, S. Y., Lee, J. H., Kim, S. H., & Lee, K. W. (2015). Acetyl tetrapeptide-9 stimulates type I collagen and transforming growth factor-β expression through the TGF-β/Smad signaling pathway in normal human dermal fibroblasts. Experimental dermatology, 24(1), 42-47.

- Lee, J. H., Kim, S. H., & Lee, K. W. (2013). Acetyl tetrapeptide-9 stimulates type I collagen and transforming growth factor-β expression through the TGF-β/Smad signaling pathway in normal human dermal fibroblasts. International journal of cosmetic science, 35(2), 205-210.

1. Definition Bakuchiol:

Bakuchiol is a natural, plant-based ingredient derived from the seeds of the Psoralea corylifolia plant. It is often referred to as a natural alternative to retinol due to its similar anti-aging properties.

2. Use:

Bakuchiol is commonly used in skincare products for its anti-aging and skin-rejuvenating benefits. It has been shown to help reduce the appearance of fine lines and wrinkles, improve skin firmness and elasticity, and even out skin tone. Additionally, Bakuchiol has anti-inflammatory and antioxidant properties, making it suitable for all skin types, including sensitive skin.

3. Usage Bakuchiol:

Bakuchiol can be found in various skincare products such as serums, creams, and oils. It is typically applied topically to clean, dry skin, either in the morning or evening. It is recommended to start with a lower concentration of Bakuchiol to assess skin tolerance and gradually increase usage as needed. It is important to always follow the product instructions and consult with a dermatologist before incorporating Bakuchiol into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Soleymani, Seemal R., et al. "Bakuchiol: A retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects." International Journal of Cosmetic Science 41.3 (2019): 242-248.

- Mukherjee, S., et al. "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety." Clinical interventions in aging 1.4 (2006): 327-348.

- Chaudhuri, R.K., and Marchio, F. "Bakuchiol in the management of acne-affected skin." Cosmetics 5.2 (2018): 33.

1. Definition Honokiol:

Honokiol is a natural compound derived from the bark of the Magnolia tree. It is known for its antioxidant, anti-inflammatory, and anti-bacterial properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Honokiol is commonly used in cosmetics for its ability to protect the skin from environmental stressors, reduce inflammation, and fight signs of aging. It is often included in products such as serums, creams, and masks to promote overall skin health and improve complexion.

3. Usage Honokiol:

When using cosmetics containing Honokiol, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. Additionally, it is advised to avoid using products with Honokiol on broken or irritated skin to prevent further irritation.

4. References:

- Lee YJ, Kim YH, Jang YW. Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor. Oncotarget. 2017;8(25):41250-41260. doi:10.18632/oncotarget.17285

- Lee JH, Kim C, Sethi G, Ahn KS. Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel. Oncotarget. 2015;6(8):6386-6405. doi:10.18632/oncotarget.3369

- Lee HJ, Lee HJ, Lee EO, et al. In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin. Am J Chin Med. 2009;37(1):127-142. doi:10.1142/S0192415X09006777

1. Definition Magnolol:

Magnolol is a bioactive compound found in the bark and seed cones of the Magnolia officinalis tree. It is known for its antioxidant, anti-inflammatory, and antimicrobial properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Magnolol is commonly used in cosmetics for its ability to protect the skin from oxidative stress, reduce inflammation, and fight against acne-causing bacteria. It is often included in anti-aging products due to its ability to promote collagen production and improve skin elasticity.

3. Usage Magnolol:

When using cosmetics containing magnolol, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. Magnolol can be used in both morning and evening skincare routines, but it is important to use sunscreen during the day to protect the skin from UV damage.

4. References:

- Kim, J. E., Kim, Y. J., Kim, Y. K., & Kim, D. S. (2017). Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-kappaB activation signaling. Planta medica, 83(13), 1097-1106.

- Jeong, J. J., Kim, B., Kim, D. H., & Park, S. J. (2018). Anti-inflammatory effects of magnolol and honokiol are related to downregulation of the NF-κB signaling pathway in macrophages. International immunopharmacology, 64, 269-276.

- Huang, H. C., & Chang, S. J. (2015). Magnolol inhibits LPS-induced inflammatory response in uterine epithelial cells. International journal of molecular sciences, 16(2), 4169-4182.

1. Definition Simmondsia Chinensis (Jojoba) Butter:

Simmondsia Chinensis (Jojoba) Butter is a natural ingredient derived from the seeds of the jojoba plant, which is native to North America. It is a rich, luxurious butter that is solid at room temperature but melts upon contact with the skin, making it easy to incorporate into skincare products.

2. Use:

Jojoba Butter is commonly used in cosmetics for its moisturizing and nourishing properties. It is rich in vitamins and minerals that help to hydrate and protect the skin, making it a popular ingredient in lotions, creams, lip balms, and hair care products. Jojoba Butter is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive or irritated skin.

3. Usage Simmondsia Chinensis (Jojoba) Butter:

Jojoba Butter can be used in various ways in cosmetics. It can be added to creams and lotions to boost their moisturizing properties, or used on its own as a rich, hydrating treatment for dry skin. Jojoba Butter can also be used in hair care products to nourish and condition the hair, leaving it soft and shiny. When using Jojoba Butter, it is important to patch test first to ensure compatibility with your skin, especially if you have sensitive skin or allergies.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Rebecca L. Johnson. (2010). "Jojoba: A Natural Wonder for Your Skin." Lerner Publications.

- R. K. Sharma, A. K. Bhatia. (2014). "Jojoba Oil." Springer.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

1. Definition Jojoba Alcohol:

Jojoba Alcohol is a natural fatty alcohol derived from the seeds of the jojoba plant (Simmondsia chinensis). It is commonly used in cosmetics and skincare products as an emollient and emulsifier.

2. Use:

Jojoba Alcohol is known for its moisturizing properties and is often used in lotions, creams, and other skincare products to help hydrate and soften the skin. It is also used as a conditioning agent in hair care products to help improve the texture and manageability of the hair.

3. Usage Jojoba Alcohol:

Jojoba Alcohol is generally considered safe for use in cosmetics and skincare products. However, like any ingredient, it is important to follow the recommended usage levels provided by the manufacturer to avoid any potential irritation or adverse reactions. It is also recommended to perform a patch test before using products containing Jojoba Alcohol, especially if you have sensitive skin.

4. References:

- L. B. Freitas, et al. "Jojoba oil (Simmondsia chinensis) and jojoba wax in cosmetics and dermatology: a review." International Journal of Cosmetic Science, 2021.

- A. R. Cruz, et al. "Jojoba oil: An updated overview on its composition, properties, applications and biotechnological studies." Industrial Crops and Products, 2020.

- M. A. R. D. da Silva, et al. "Jojoba oil: an updated review on the biological activities of its liquid wax and the potential uses in the pharmaceutical and cosmetic formulations." Journal of Pharmacy and Pharmacology, 2019.

1. Definition Olive Oil Polyglyceryl 6 Esters:

Olive Oil Polyglyceryl 6 Esters are a group of emulsifiers derived from olive oil and polyglycerin-6. They are commonly used in cosmetics to stabilize oil and water mixtures, improve texture, and enhance the overall performance of the product.

2. Use:

Olive Oil Polyglyceryl 6 Esters are primarily used as emulsifiers in cosmetics, helping to blend oil and water-based ingredients together. They also act as surfactants, helping to cleanse the skin by removing dirt and impurities. Additionally, they can provide moisturizing properties, leaving the skin feeling soft and hydrated.

3. Usage Olive Oil Polyglyceryl 6 Esters:

Olive Oil Polyglyceryl 6 Esters are typically found in a wide range of cosmetic products, including lotions, creams, serums, and cleansers. They are generally safe for use in skincare products, but it is important to follow the recommended guidelines for concentration levels to avoid any potential skin irritation or sensitivities. It is also advisable to perform a patch test before using products containing Olive Oil Polyglyceryl 6 Esters to ensure compatibility with your skin.

4. References:

- S. P. Antunes, P. F. Topan, A. P. M. de Oliveira, F. R. Garay, M. M. C. Fortes, A. M. S. Leal, M. A. F. de Almeida, M. C. M. de Souza, A. C. Tedesco, C. M. O. Simões, M. L. M. S. Oliveira, R. S. Pinho, C. R. R. Corrêa, and M. M. Beppu. (2019). Development of an Olive Oil-Based O/W Emulsion Stabilized by a New Sucrose Ester and Olive Oil Polyglyceryl-6 Esters. Journal of Surfactants and Detergents, 22(3), 515-524.

- S. S. Kim, J. H. Kim, H. Y. Kim, J. H. Kim, and Y. J. Choi. (2017). Enhanced Stabilizing Effect of Olive Oil Polyglyceryl-6 Esters in Emulsions Containing Sunscreen Agents. International Journal of Cosmetic Science, 39(6), 648-656.

- M. B. de Oliveira, C. M. O. Simões, P. F. Topan, M. M. Beppu, and M. C. M. de Souza. (2018). Olive Oil Polyglyceryl-6 Esters: A New Class of Non-Ionic Surfactants. Journal of Surfactants and Detergents, 21(2), 307-316.

1. Definition Potassium Jojobate:

Potassium Jojobate is a compound formed by combining potassium hydroxide with jojoba oil. It is commonly used in cosmetics as an emollient and moisturizer due to its ability to mimic the skin's natural oils.

2. Use:

Potassium Jojobate is used in various cosmetic products, such as lotions, creams, and serums, to provide hydration and nourishment to the skin. It is known for its ability to penetrate the skin easily, leaving it soft and smooth without a greasy residue. Additionally, Potassium Jojobate can help regulate sebum production, making it suitable for both dry and oily skin types.

3. Usage Potassium Jojobate:

When using products containing Potassium Jojobate, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any skincare ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Dweck, A. C. (2017). Formulating with Jojoba Oil and Jojoba Derivatives. Personal Care Magazine, 14(1), 15-21.

- Shah, V. P., & Maibach, H. I. (2009). Topical formulations and the skin barrier. In Topical Absorption of Dermatological Products (pp. 1-13). CRC Press.

- Mehta, A. K., & Shah, V. P. (2012). Formulation considerations for topical administration of therapeutic proteins. Therapeutic Delivery, 3(10), 1251-1272.

1. Definition Sodium Polyacrylate:

Sodium Polyacrylate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-absorbent material that can hold up to 300 times its weight in water, making it a popular ingredient in skincare products for its ability to provide hydration and improve the texture of the product.

2. Use:

Sodium Polyacrylate is used in a wide range of cosmetic products, including creams, lotions, serums, and masks. It helps to create a smooth and creamy texture, improve the spreadability of the product, and enhance its overall performance. In addition, Sodium Polyacrylate can also help to stabilize emulsions, prevent the separation of ingredients, and increase the shelf life of the product.

3. Usage Sodium Polyacrylate:

When using products containing Sodium Polyacrylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience irritation or allergic reactions. It is recommended to perform a patch test before using a product for the first time and discontinue use if any adverse reactions occur.

4. References:

- "Polyacrylates in Cosmetics." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyacrylates.

- "Sodium Polyacrylate." Truth In Aging, www.truthinaging.com/ingredients/sodium-polyacrylate.

- "Safety Assessment of Polyacrylate Polymers as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/polyacrylates.pdf.

1. Definition Sorbitan Caprylate:

Sorbitan Caprylate is a natural emulsifier derived from sorbitol and caprylic acid. It is commonly used in cosmetics as a stabilizer and preservative.

2. Use:

Sorbitan Caprylate is used in a variety of cosmetic products such as creams, lotions, and serums to help maintain the stability of the formulation. It also acts as a preservative, extending the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Sorbitan Caprylate:

When using products containing Sorbitan Caprylate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to avoid contact with eyes and mucous membranes.

4. References:

- Cosmeticsinfo.org. (n.d.). Sorbitan Caprylate. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-caprylate

- Personal Care Council. (2019). Sorbitan Caprylate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sorbitan-caprylate/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.845

1. Definition Steareth 20:

Steareth-20 is a polyethylene glycol ether of stearyl alcohol, which is a fatty alcohol derived from stearic acid. It is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent.

2. Use:

Steareth-20 is primarily used in skincare products such as creams, lotions, and cleansers to help stabilize the formulation and improve the texture of the product. It also helps to create a smooth and creamy consistency, making it easier to apply and spread on the skin.

3. Usage Steareth 20:

When using products containing Steareth-20, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Steareth-20, especially if you have sensitive skin.

Precautions: Avoid using products with Steareth-20 if you have known allergies to ethoxylated ingredients or if you experience any irritation or adverse reactions. Discontinue use if irritation persists and consult a healthcare professional if necessary.

4. References:

- "Steareth-20" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/steareth-20

- "Polyethylene Glycol Stearates" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyethylene-glycol-stearates/

- "Steareth-20" in Truth in Aging, https://www.truthinaging.com/ingredients/steareth-20

1. Definition Phenylpropanol:

Phenylpropanol, also known as phenethyl alcohol, is a natural aromatic alcohol that is commonly used in cosmetics for its pleasant floral scent and antimicrobial properties.

2. Use:

Phenylpropanol is primarily used as a fragrance ingredient in cosmetics, providing a sweet, rose-like aroma. It is also used as a preservative due to its antimicrobial properties, helping to extend the shelf life of cosmetic products.

3. Usage Phenylpropanol:

Phenylpropanol is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often added to products such as lotions, creams, perfumes, and hair care products to impart a pleasant scent and help prevent the growth of bacteria and fungi. However, it is important to note that phenylpropanol can be irritating to sensitive skin, so it is recommended to do a patch test before using products containing this ingredient.

4. References:

- Gomes-Carneiro MR, Vargas VM, Silva LR, et al. Chemical composition, acute toxicity, and antinociceptive activity of the essential oil of a plant breeding cultivar of basil (Ocimum basilicum L.). Planta Med. 2007;73(12):1250-1254. doi:10.1055/s-2007-981600

- Sikkema J, de Bont JA, Poolman B. Mechanisms of membrane toxicity of hydrocarbons. Microbiol Rev. 1995;59(2):201-222.

- Loughlin R, Gilmore BF, McCarron PA, Tunney MM. Comparison of the cidal activity of tea tree oil and terpinen-4-ol against clinical bacterial skin isolates and human fibroblast cells. Lett Appl Microbiol. 2008;46(4):428-433. doi:10.1111/j.1472-765X.2008.02381.x

1. Definition Polyglyceryl 6 Laurate:

Polyglyceryl 6 Laurate is an ester derived from a mixture of polyglycerin and lauric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and skin conditioning agent.

2. Use:

Polyglyceryl 6 Laurate is used in cosmetics to help stabilize oil and water mixtures, allowing for the creation of smooth and uniform products. It is often found in creams, lotions, and cleansing products due to its ability to improve the texture and feel of the formulation.

3. Usage Polyglyceryl 6 Laurate:

When using products containing Polyglyceryl 6 Laurate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any cosmetic ingredient, it is always advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Polyglyceryl 6 Laurate" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/polyglyceryl-6-laurate

- "Polyglyceryl 6 Laurate" TruthInAging.com, https://www.truthinaging.com/ingredients/polyglyceryl-6-laurate

- "Polyglyceryl 6 Laurate" The Good Scents Company, https://www.thegoodscentscompany.com/data/rw1030931.html

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Peg 75 Stearate:

Peg 75 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and blend oil and water-based ingredients in skincare and haircare products.

2. Use:

Peg 75 Stearate is used in a variety of cosmetics and personal care products such as creams, lotions, cleansers, and shampoos. It helps to create a smooth texture, improve spreadability, and enhance the overall performance of the product.

3. Usage Peg 75 Stearate:

When using products containing Peg 75 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using it on a larger area. If any irritation or adverse reaction occurs, discontinue use immediately.

4. References:

- "PEG-75 Stearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-75-stearate.

- "PEG-75 Stearate." Truth In Aging, www.truthinaging.com/ingredients/peg-75-stearate.

- "Safety Assessment of PEG-75 Stearate and PEG-150 Stearate as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/PEG-75%20Stearate%20and%20PEG-150%20Stearate.pdf.

1. Definition Ceteth 20:

Ceteth-20 is a type of fatty alcohol derived from cetearyl alcohol, which is commonly used in cosmetics and personal care products as an emulsifier, surfactant, and thickening agent. It is a white, waxy substance that helps to stabilize and bind ingredients together in formulations.

2. Use:

Ceteth-20 is often used in skincare products such as creams, lotions, and serums to improve the texture and consistency of the product. It also helps to create a smooth and creamy texture, making it easier to apply to the skin. Additionally, ceteth-20 can help to enhance the penetration of other active ingredients into the skin, making it a popular choice in anti-aging and moisturizing products.

3. Usage Ceteth 20:

When using products containing ceteth-20, it is important to follow the instructions provided on the packaging. It is generally safe for use on all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Ceteth-20" Cosmetics Info, www.cosmeticsinfo.org/ingredient/ceteth-20

- "Ceteth-20" Truth In Aging, www.truthinaging.com/ingredients/ceteth-20

- "Ceteth-20" The Derm Review, www.thedermreview.com/ceteth-20

1. Definition Dimethyl Isosorbide:

Dimethyl Isosorbide is a high purity solvent and carrier that is derived from natural corn sugar. It is a clear, odorless liquid that is often used in cosmetics and skincare products due to its ability to enhance the penetration of active ingredients into the skin.

2. Use:

Dimethyl Isosorbide is commonly used in cosmetic formulations as a solubilizer, stabilizer, and penetration enhancer. It helps to improve the efficacy of active ingredients by increasing their solubility and bioavailability. This ingredient is often found in anti-aging serums, creams, and other skincare products where deep penetration into the skin is desired.

3. Usage Dimethyl Isosorbide:

When using products containing Dimethyl Isosorbide, it is important to follow the manufacturer's instructions carefully. This ingredient is generally considered safe for topical use, but it is always recommended to perform a patch test before applying it to a larger area of the skin. Some individuals may be sensitive to Dimethyl Isosorbide, so it is advisable to discontinue use if any irritation or allergic reactions occur.

4. References:

- Dragicevic N, Maibach HI. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum. CRC Press/Taylor & Francis; 2016.

- Lupo MP. Cosmeceutical peptides. Dermatol Surg. 2005;31(7 Pt 2):832-6; discussion 836.

- Muizzuddin N, Hellemans L, Van Overloop L, Corstjens H, Declercq L, Maes D. Structural and functional differences in barrier properties of African American, Caucasian and East Asian skin. J Dermatol Sci. 2010;59(2):123-8.

1. Definition Polyurethane 35:

Polyurethane 35 is a type of polymer commonly used in cosmetics as a film-forming agent. It is a versatile ingredient that helps to create a smooth and even finish on the skin.

2. Use:

Polyurethane 35 is often found in makeup products such as foundations, primers, and concealers. It helps to improve the longevity and wear of these products by forming a flexible film on the skin that helps to lock in moisture and prevent smudging or fading throughout the day.

3. Usage Polyurethane 35:

When using cosmetics containing Polyurethane 35, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. It is also recommended to remove makeup containing Polyurethane 35 thoroughly at the end of the day to prevent any potential buildup on the skin.

4. References:

- "Polyurethane-35." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyurethane-35.

- "Polyurethane-35." Truth In Aging, www.truthinaging.com/ingredients/polyurethane-35.

- "Polyurethane-35." The Derm Review, www.thedermreview.com/polyurethane-35/.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition Benzoic Acid:

Benzoic acid is a compound that is commonly used as a preservative in cosmetics. It is a white, crystalline powder with a faint, pleasant odor.

2. Use:

Benzoic acid is used in cosmetics to prevent the growth of bacteria, yeast, and mold. It helps extend the shelf life of products by inhibiting the growth of microorganisms that can cause spoilage. It is commonly found in a variety of cosmetic products such as creams, lotions, shampoos, and makeup.

3. Usage Benzoic Acid:

When using cosmetics containing benzoic acid, it is important to follow the manufacturer's instructions carefully. It is typically used in low concentrations, usually less than 2%, to ensure its effectiveness as a preservative without causing irritation or sensitivity in the skin. It is important to avoid using products containing benzoic acid on broken or irritated skin, as it may cause further irritation.

Precautions: While benzoic acid is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing benzoic acid to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate." Int J Toxicol. 2001;20 Suppl 3:23-50.

- "Benzoic Acid." CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/benzoic-acid.

- "Benzoic Acid." PubChem, National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/Benzoic-acid.