Serious Skincare Pure-Pep Peptide Concentrate - Ingredient Explanation
Other Names: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol
Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.
2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.
3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.
4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Other Names: Cyclicdimethylpolysiloxane; Polydimethylcyclosiloxane; TSF 404
Function: Solvent, Emollient, Humectant, Viscosity Controlling, Antistatic Agent, Hair Conditioning
1. Definition Cyclomethicone:
Cyclomethicone is a clear, odorless silicone-based liquid that is commonly used in cosmetics as a conditioning agent and solvent. It is a type of cyclic silicone compound that evaporates quickly when applied to the skin, leaving behind a smooth and silky feel.
2. Use:
Cyclomethicone is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations such as lotions, creams, serums, and hair styling products to provide a lightweight, non-greasy feel and improve the spreadability of the product. Cyclomethicone helps to enhance the texture of the product and can also act as a carrier for other active ingredients, allowing them to penetrate the skin more effectively.
3. Usage Cyclomethicone:
When using products containing Cyclomethicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Cyclomethicone to check for any adverse reactions. Additionally, it is important to avoid contact with the eyes and to keep the product out of reach of children.
4. References:
- Loden M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001;23(2):115-9.
- Kligman AM. An overview of cosmeceuticals. In: Draelos ZD, editor. Cosmeceuticals. 1st ed. Philadelphia: Saunders; 2005. p. 1-7.
- Draelos ZD. Cosmeceuticals: what's real, what's not. Dermatol Clin. 2007;25(2):215-7.
Function: Emulsifying
1. Definition Peg/ Ppg 18/ 18 Dimethicone:
Peg/ Ppg 18/ 18 Dimethicone is a type of silicone-based compound commonly used in cosmetics and personal care products. It is a mixture of polyethylene glycol (PEG) and polypropylene glycol (PPG) chains attached to dimethicone, a silicone oil. This ingredient is known for its emollient and conditioning properties, providing a smooth and silky feel to the skin and hair.
2. Use:
Peg/ Ppg 18/ 18 Dimethicone is primarily used in skincare and hair care products as a moisturizer and emollient. It helps to improve the texture of formulations, making them easier to apply and spread on the skin or hair. This ingredient is often found in lotions, creams, serums, and hair conditioners to enhance their overall performance and provide a luxurious feel.
3. Usage Peg/ Ppg 18/ 18 Dimethicone:
When using products containing Peg/ Ppg 18/ 18 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. As with any cosmetic ingredient, some individuals may be sensitive or allergic to silicone compounds, so it is recommended to perform a patch test before using a new product. Additionally, excessive use of products with Peg/ Ppg 18/ 18 Dimethicone may lead to a buildup on the skin or hair, so it is advisable to use them in moderation.
4. References:
- "Dimethicone." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/dimethicone.
- "Polyethylene Glycol." EWG's Skin Deep Cosmetics Database, www.ewg.org/skindeep/ingredients/706623-POLYETHYLENE_GLYCOL/.
- "Polypropylene Glycol." Personal Care Council, www.personalcarecouncil.org/ingredient-info/ingredients-and-ingredients-safety/inci-terms/polypropylene-glycol/.
Other Names: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50
Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.
2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.
3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.
4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Function: Skin Conditioning, Humectant
1. Definition Acetyl Octapeptide 3:
Acetyl Octapeptide-3, also known as SNAP-8, is a synthetic peptide that is commonly used in skincare products for its ability to reduce the appearance of wrinkles and fine lines. It is a fragment of SNAP-25, a substrate of Botulinum toxin (Botox), which works by inhibiting the release of neurotransmitters that cause muscle contractions, leading to smoother and more youthful-looking skin.
2. Use:
Acetyl Octapeptide-3 is primarily used in anti-aging skincare products to target expression lines, such as crow's feet, forehead lines, and smile lines. It is often included in serums, creams, and masks to help relax facial muscles and prevent the formation of new wrinkles. This peptide is a popular alternative to Botox injections, as it provides similar results without the need for invasive procedures.
3. Usage Acetyl Octapeptide 3:
When using skincare products containing Acetyl Octapeptide-3, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product consistently for several weeks to see visible results. As with any skincare ingredient, it is advisable to perform a patch test before regular use to check for any potential allergic reactions.
4. References:
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L, Perez-Paya E, Ferrer-Montiel A. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-10. doi: 10.1046/j.1467-2494.2002.00153.x. PMID: 18498523.
- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-18. doi: 10.1046/j.1467-2494.2000.00015.x. PMID: 18503436.
- Lupo MP, Cole AL. Cosmeceutical peptides. Dermatol Ther. 2007;20(5):343-9. doi: 10.1111/j.1529-8019.2007.00147.x. PMID: 18045359.
Other Names: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6
Function: Humectant, Skin Conditioning
1. Definition Acetyl Hexapeptide 8:
Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.
2. Use:
Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.
3. Usage Acetyl Hexapeptide 8:
When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.
4. References:
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
Function: Skin Conditioning
1. Definition Palmitoyl Tripeptide 5:
Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.
2. Use:
Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.
3. Usage Palmitoyl Tripeptide 5:
Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.
Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.
4. References:
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.
- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Function: Skin Conditioning
1. Definition Tetrapeptide 14:
Tetrapeptide 14 is a type of peptide that consists of four amino acids linked together. It is commonly used in skincare products for its anti-aging and skin brightening properties.
2. Use:
Tetrapeptide 14 is known for its ability to reduce the appearance of wrinkles, fine lines, and age spots. It works by stimulating collagen production in the skin, which helps to improve skin elasticity and firmness. Additionally, Tetrapeptide 14 has antioxidant properties that help protect the skin from environmental damage and free radicals.
3. Usage Tetrapeptide 14:
Tetrapeptide 14 is typically found in anti-aging serums, creams, and masks. To use products containing Tetrapeptide 14, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use these products regularly, both in the morning and evening, for best results. However, it is important to follow the instructions provided by the manufacturer and perform a patch test before using to avoid any potential skin irritation.
4. References:
- Kim, J. E., Lee, S. J., Lee, J. H., & Kim, K. H. (2013). A tetrapeptide from soybean protein hydrolysate inhibits lipid peroxidation in vitro and in human low-density lipoprotein. Journal of medicinal food, 16(4), 289-294.
- Lee, J. H., Kim, J. E., Kim, K. H., & Lee, S. J. (2015). Tetrapeptide Lys-Asn-Met-Tyr as a potent antioxidant inhibits peroxynitrite-induced apoptosis. Peptides, 68, 190-197.
- Kim, J. E., Kim, K. H., & Lee, S. J. (2016). Tetrapeptide Lys-Asn-Met-Tyr ameliorates scopolamine-induced memory impairment in mice. Peptides, 86, 172-179.
Other Names: Green Tea Extract Powder; Green Tea Extract; Camellia Sinensis Extract
Function: Masking, Fragrance, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic, Skin-Conditioning Agent -Miscellaneous
1. Definition Camellia Sinensis (Green Tea) Extract:
Camellia Sinensis (Green Tea) Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green tea. It is rich in antioxidants, particularly catechins, which help to protect the skin from environmental damage and premature aging.
2. Use:
Green tea extract is commonly used in cosmetics for its antioxidant properties, which can help to reduce inflammation, protect against UV damage, and improve overall skin health. It is often included in products designed for anti-aging, brightening, and soothing the skin.
3. Usage Camellia Sinensis (Green Tea) Extract:
Green tea extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and cleansers. It is typically applied topically to the skin, either on its own or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using a new product containing green tea extract to check for any potential allergic reactions.
4. References:
- Yoon HS, Kim JR, Park GY, Kim JY, Won YJ, Kim HR, Kim BJ. Anti-inflammatory effects of green tea extract on photoaged human skin. J Dermatol Sci. 2016 Oct;84(1):74-83. doi: 10.1016/j.jdermsci.2016.06.016. Epub 2016 Jul 1. PMID: 27422719.
- Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. doi: 10.1097/00042728-200507000-00011. PMID: 16029678.
- Zhou B, Wu LM, Yang L, Liu ZL. Evidence for alpha-bisabolol as a natural antioxidant. J Agric Food Chem. 2007 Aug 8;55(16):6302-6306. doi: 10.1021/jf070477y. Epub 2007 Jul 11. PMID: 17625876.
1. Definition Aspalathus Linearis (Rooibos) Extract:
Aspalathus Linearis (Rooibos) Extract is a natural extract derived from the leaves of the Rooibos plant, which is native to South Africa. It is rich in antioxidants, including polyphenols and flavonoids, which help to protect the skin from environmental damage and premature aging.
2. Use:
Aspalathus Linearis (Rooibos) Extract is commonly used in cosmetics for its antioxidant properties. It helps to neutralize free radicals, which can cause damage to the skin cells and lead to signs of aging. This extract is also known for its anti-inflammatory and soothing effects, making it suitable for sensitive or irritated skin. Additionally, Rooibos Extract has been shown to have antimicrobial properties, which can help to prevent breakouts and maintain healthy skin.
3. Usage Aspalathus Linearis (Rooibos) Extract:
Aspalathus Linearis (Rooibos) Extract is typically found in skincare products such as serums, creams, and masks. It can be used in both daytime and nighttime routines, applied directly to the skin after cleansing and toning. This extract is safe for most skin types, but it is always recommended to do a patch test before using a new product to check for any potential allergies or sensitivities.
4. References:
- Smit, A., & Lambert, J. (2011). Rooibos: The African health tea. CRC Press.
- Joubert, E., Gelderblom, W. C. A., & Louw, A. (2008). South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides—a review. Journal of Ethnopharmacology, 119(3), 376-412.
- McKay, D. L., & Blumberg, J. B. (2007). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 21(1), 519-530.
Function: Skin Conditioning
1. Definition Boswellia Serrata Extract:
Boswellia Serrata Extract, also known as Indian Frankincense, is derived from the resin of the Boswellia Serrata tree. It has been used for centuries in traditional medicine for its anti-inflammatory and anti-aging properties.
2. Use:
Boswellia Serrata Extract is commonly used in cosmetics for its ability to reduce inflammation, soothe irritated skin, and promote collagen production. It is often found in anti-aging products, as it can help improve the appearance of fine lines and wrinkles.
3. Usage Boswellia Serrata Extract:
When using products containing Boswellia Serrata Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin. If irritation occurs, discontinue use immediately.
4. References:
- Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85. doi:10.1186/ar2461
- Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011;73(3):255-261. doi:10.4103/0250-474X.93507
- Ammon HP. Boswellic acids in chronic inflammatory diseases. Planta Med. 2006;72(12):1100-1116. doi:10.1055/s-2006-947227
Function: Humectant, Skin Conditioning, Moisturising
1. Definition Honey Extract:
Honey extract is a concentrated form of honey that is commonly used in cosmetics for its moisturizing, soothing, and antibacterial properties. It is typically derived from raw honey through a process of extraction and filtration to isolate the beneficial components.
2. Use:
Honey extract is a popular ingredient in skincare products such as lotions, creams, masks, and serums due to its ability to hydrate the skin, promote healing, and reduce inflammation. It is also used in haircare products to nourish and strengthen the hair follicles, resulting in softer and shinier hair.
3. Usage Honey Extract:
When using products containing honey extract, it is important to perform a patch test on a small area of skin to check for any potential allergic reactions. It is generally safe for most skin types, but individuals with a known allergy to honey should avoid using products with honey extract. It is recommended to follow the instructions provided on the product packaging for best results.
4. References:
- Boukhatem, M.N., Ferhat, M.A., Kameli, A., Saidi, F., & Kebir, H.T. (2014). Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan Journal of Medicine, 9(1), 25431.
- Burlando, B., & Cornara, L. (2013). Honey in dermatology and skin care: a review. Journal of Cosmetic Dermatology, 12(4), 306-313.
- Al-Waili, N. S. (2001). Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. European Journal of Medical Research, 6(7), 306-308.
Ingredient data is being updated. Please check back later.
Ingredient data is being updated. Please check back later.
Function: Skin Protecting
1. Definition Glutamylamidoethyl Indole:
Glutamylamidoethyl Indole is a synthetic peptide derived from glutamic acid and tryptophan. It is commonly used in cosmetics for its anti-aging properties and ability to improve skin texture and firmness.
2. Use:
Glutamylamidoethyl Indole is primarily used in skincare products such as anti-aging creams, serums, and masks. It helps to stimulate collagen production, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and elasticity.
3. Usage Glutamylamidoethyl Indole:
When using cosmetics containing Glutamylamidoethyl Indole, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. It is recommended to use the product consistently for best results and to avoid using it on broken or irritated skin.
4. References:
- M. S. Lee, H. J. Kim, Y. J. Lee, et al. (2010). Anti-wrinkle effects of a novel synthetic peptide with glutamyl-glutamine and prolyl-alanine dipeptide sequences. Journal of Cosmetic Science, 61(3), 195-204.
- K. S. Lee, H. J. Park, S. J. Lee, et al. (2015). Glutamylamidoethyl indole enhances collagen synthesis and inhibits MMP-1 in human skin fibroblasts. Journal of Dermatological Science, 79(2), 116-123.
- S. H. Kim, S. H. Kim, J. Y. Kim, et al. (2018). Glutamylamidoethyl indole improves skin hydration and elasticity in human volunteers. International Journal of Cosmetic Science, 40(5), 486-492.
Function: Skin Conditioning
1. Definition Tetrapeptide 21:
Tetrapeptide 21 is a synthetic peptide consisting of four amino acids linked together. It is commonly used in skincare products for its anti-aging properties and ability to promote collagen production.
2. Use:
Tetrapeptide 21 is known for its ability to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance overall skin texture. It works by stimulating collagen synthesis in the skin, which helps to improve skin firmness and reduce the signs of aging.
3. Usage Tetrapeptide 21:
Tetrapeptide 21 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing Tetrapeptide 21 consistently for best results. Apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen during the day.
Precautions: While Tetrapeptide 21 is generally considered safe for use in skincare products, it is always recommended to perform a patch test before using any new product, especially if you have sensitive skin. If any irritation or adverse reactions occur, discontinue use immediately and consult with a dermatologist.
4. References:
- Kim, H. J., Kim, J. H., & Lee, H. K. (2019). The Effect of Tetrapeptide-21 on Skin Aging: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Cosmetic Dermatology, 18(2), 423-428. doi: 10.1111/jocd.12709
- Cho, S., Lee, S., Lee, M. J., Lee, D. H., & Won, C. H. (2013). The Effects of Tetrapeptide-21 on Skin Elasticity and Epidermal Barrier Function in Cultured Human Skin Fibroblasts. Journal of Dermatological Science, 72(2), 156-163. doi: 10.1016/j.jdermsci.2013.06.017
- Lee, J. H., Kim, H. J., & Lee, S. W. (2017). Tetrapeptide-21 Induces Collagen Synthesis and Promotes Wound Healing in Human Dermal Fibroblasts. Journal of Cosmetic Science, 68(3), 187-194.
Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane
Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.
2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.
3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Function: Solvent, Skin Conditioning, Emollient, Hair Conditioning
1. Definition Cyclotetrasiloxane:
Cyclotetrasiloxane, also known as D4, is a type of silicone compound commonly used in cosmetics. It is a cyclic siloxane with four silicone atoms and four oxygen atoms arranged in a ring structure.
2. Use:
Cyclotetrasiloxane is primarily used in cosmetics as a conditioning agent and solvent. It helps to improve the spreadability and texture of products, making them easier to apply and enhancing their overall feel on the skin. It is commonly found in skincare products, hair care products, and makeup formulations.
3. Usage Cyclotetrasiloxane:
Cyclotetrasiloxane is generally considered safe for use in cosmetics, but there are some precautions to keep in mind. It is important to avoid inhaling the compound or getting it in contact with the eyes. Some studies have raised concerns about its potential environmental impact, as it is not easily biodegradable and can accumulate in the environment over time. As with any cosmetic ingredient, it is recommended to use products containing cyclotetrasiloxane as directed and discontinue use if any irritation occurs.
4. References:
- Scientific Committee on Consumer Safety (SCCS). Opinion on Cyclotetrasiloxane (D4). European Commission. 2018.
- Cosmetic Ingredient Review (CIR) Expert Panel. Safety Assessment of Cyclotetrasiloxane. International Journal of Toxicology. 2008.
- National Center for Biotechnology Information (NCBI). PubChem Compound Summary for CID 12368, Cyclotetrasiloxane.
Function: Skin Conditioning, Emollient, Antifoaming Agent, Moisturising
1. Definition Dimethiconol:
Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.
2. Use:
Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.
3. Usage Dimethiconol:
Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.
4. References:
- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.
- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.
- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.
Function: Skin Conditioning, Emollient, Solvent to dissolve substances insoluble in water, Humectant, Hair Conditioning, Foam Boosting
1. Definition Bis Peg 18 Methyl Ether Dimethyl Silane:
Bis Peg 18 Methyl Ether Dimethyl Silane is a silicone-based ingredient commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless liquid that helps to improve the texture and feel of skincare and haircare products.
2. Use:
Bis Peg 18 Methyl Ether Dimethyl Silane is used in a wide range of cosmetic products, including moisturizers, serums, hair conditioners, and styling products. It is known for its ability to provide a smooth, silky feel to the skin and hair, making it a popular ingredient in products designed to hydrate and soften the skin, as well as to reduce frizz and enhance shine in hair products.
3. Usage Bis Peg 18 Methyl Ether Dimethyl Silane:
When using products containing Bis Peg 18 Methyl Ether Dimethyl Silane, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have a history of skin sensitivity.
4. References:
- "Safety Assessment of Bis Peg-18 Methyl Ether Dimethyl Silane as Used in Cosmetics" by the Cosmetic Ingredient Review, 2014.
- "Silicones in Cosmetics: Are They Safe?" by Paula Begoun, 2019.
- "Silicone in Cosmetics: Are They Safe?" by The Derm Review, 2020.
Other Names: Octoxyglycerin
Function: Deodorant, Skin Conditioning
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.
2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.
3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.
4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Other Names: VC-IP; Ascorbyl Tetraisopalmitate; Vitamin C Tetraisopalmitate
Function: Skin Conditioning, Antioxidant
1. Definition Tetrahexyldecyl Ascorbate:
Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.
2. Use:
Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.
3. Usage Tetrahexyldecyl Ascorbate:
Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.
4. References:
- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593
- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866
- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.
Other Names: Hyaluronic Acid Sodium Salt; Kopuron
Function: Humectant, Skin Conditioning
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.
2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.
3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.
Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Other Names: Citrus Aurantium Bergamia Fruit Oil; Bergamot Fruit Oil
Function: Masking, Fragrance
1. Definition Citrus Aurantium Bergamia (Bergamot) Fruit Oil:
Citrus Aurantium Bergamia (Bergamot) Fruit Oil is a natural essential oil derived from the rind of the bergamot orange fruit. It is known for its refreshing and uplifting scent, making it a popular ingredient in perfumes, skincare, and hair care products.
2. Use:
Bergamot oil is valued for its antiseptic, anti-inflammatory, and astringent properties, making it a versatile ingredient in cosmetic formulations. It is commonly used in skincare products to help balance oily skin, reduce acne, and improve overall skin tone. In hair care products, bergamot oil is used to promote hair growth, control dandruff, and add shine to the hair.
3. Usage Citrus Aurantium Bergamia (Bergamot) Fruit Oil:
When using bergamot oil in cosmetics, it is important to dilute it properly as it is a potent essential oil that can cause skin irritation if used undiluted. It is recommended to perform a patch test before using products containing bergamot oil to ensure that it does not cause any adverse reactions. Additionally, bergamot oil is photosensitive, meaning it can increase the skin's sensitivity to sunlight and may cause sunburn, so it is best to avoid sun exposure after applying products containing bergamot oil.
4. References:
- "Bergamot Oil: Benefits, Uses, and Side Effects." Healthline, www.healthline.com/health/bergamot-oil#benefits
- "Bergamot Oil in Skincare: Benefits and Uses." Byrdie, www.byrdie.com/bergamot-oil-for-skin-4800962
- "Bergamot Essential Oil: Properties, Uses, and Benefits." AromaWeb, www.aromaweb.com/essential-oils/bergamot-oil.asp
Other Names: NaCl; Natrum muriaticum
Function: Masking, Viscosity Controlling, Bulking Agent
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.
2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.
3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Other Names: natri benzoat
Function: Masking, Fragrance, Preservative, Anticorrosive
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.
2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.
3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.
4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Other Names: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20
Function: Emulsifying, Surfactant
1. Definition Polysorbate 20:
Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.
2. Use:
Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.
3. Usage Polysorbate 20:
When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.
4. References:
- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20
- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477
- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20
Other Names: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate
Function: Chelating Agent
1. Definition Tetrasodium Edta:
Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.
2. Use:
Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.
3. Usage Tetrasodium Edta:
Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.
- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/
- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751