Sesderma Azelac Moisturising Gel

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

1. Definition Potassium Azeloyl Diglycinate:

Potassium Azeloyl Diglycinate is a water-soluble derivative of azelaic acid, a naturally occurring acid found in grains like barley, wheat, and rye. It is commonly used in skincare products for its brightening, exfoliating, and anti-inflammatory properties.

2. Use:

Potassium Azeloyl Diglycinate is primarily used in cosmetics and skincare products as a skin brightening agent. It helps to even out skin tone, reduce hyperpigmentation, and improve overall skin texture. Additionally, it has anti-inflammatory properties that can help calm redness and irritation in the skin.

3. Usage Potassium Azeloyl Diglycinate:

Potassium Azeloyl Diglycinate is typically found in serums, creams, and lotions targeted towards individuals looking to improve the appearance of their skin. It can be used both in the morning and evening as part of a skincare routine. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have sensitive skin or any concerns about using this ingredient.

4. References:

- Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin Cosmet Investig Dermatol. 2015;8:455-61. doi: 10.2147/CCID.S84765. Epub 2015 Aug 7. PMID: 26347269; PMCID: PMC4554394.

- Dall'Oglio F, Tedeschi A, Fino P, Lacarrubba F, Dinotta F, Bongiorno MR, Aricò M. A new topical azelaic acid foam: treatment for acne. Expert Opin Pharmacother. 2013 Nov;14(16):2271-9. doi: 10.1517/14656566.2013.844174. Epub 2013 Oct 9. PMID: 24102681.

- Grimes PE. The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. Dermatol Surg. 1999 Jan;25(1):18-22. doi: 10.1046/j.1524-4725.1999.08164.x. PMID: 9935084.

1. Definition Triticum Vulgare (Wheat) Germ Extract:

Triticum Vulgare (Wheat) Germ Extract is a natural ingredient derived from the germ of wheat kernels. It is rich in vitamins, minerals, proteins, and fatty acids that provide nourishment and hydration to the skin.

2. Use:

Wheat germ extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and premature aging. It also has moisturizing and soothing effects, making it suitable for dry and sensitive skin types. Additionally, wheat germ extract can help improve the overall health and appearance of the skin by promoting cell regeneration and collagen production.

3. Usage Triticum Vulgare (Wheat) Germ Extract:

Wheat germ extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations and can be applied directly to the skin or mixed with other ingredients. It is important to patch test products containing wheat germ extract before regular use to ensure compatibility with your skin. Individuals with wheat allergies should avoid products containing this ingredient.

4. References:

- Calzavara-Pinton, P., Zane, C., Arisi, M., & Capezzera, R. (2005). Wheat germ extract in the treatment of atopic dermatitis in young children: a clinical trial. Pediatric dermatology, 22(3), 184-187.

- Saraf, S., & Jeswani, G. (2010). Triticum aestivum (wheatgrass) and its Nutritional Value. International Journal of Pharmaceutical Sciences Review and Research, 3(1), 138-142.

- Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and wheat germ: Composition and benefits to health. International Journal of Food Science & Technology, 1(4), 1-8.

1. Definition Silybum Marianum Extract:

Silybum Marianum Extract, also known as Milk Thistle Extract, is a natural ingredient derived from the seeds of the milk thistle plant. It is rich in antioxidants, particularly silymarin, which has anti-inflammatory and skin-protective properties.

2. Use:

Silybum Marianum Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to protect the skin from environmental stressors, reduce redness and inflammation, and promote overall skin health. Additionally, it can help to improve the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Silybum Marianum Extract:

Silybum Marianum Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations of 0.5-2% and is suitable for all skin types, including sensitive skin. To use, apply a small amount of product containing Silybum Marianum Extract to clean, dry skin and gently massage in until fully absorbed. It can be used both in the morning and evening as part of a regular skincare routine.

4. References:

- Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61(14):2035-63.

- Surai PF, Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. Antioxidants (Basel). 2015;4(1):204-47.

- Gazák R, Walterová D, Kren V. Silybin and silymarin--new and emerging applications in medicine. Curr Med Chem. 2007;14(3):315-38.

1. Definition Azelaic Acid:

Azelaic acid is a naturally occurring dicarboxylic acid found in grains like barley, wheat, and rye. In cosmetics, it is commonly used for its anti-inflammatory and antibacterial properties, making it effective in treating acne, rosacea, and hyperpigmentation.

2. Use:

Azelaic acid is used in skincare products such as creams, gels, and serums to help improve the appearance of skin by reducing inflammation, unclogging pores, and fading dark spots. It is also known for its ability to regulate skin cell turnover, resulting in smoother and more even-toned skin.

3. Usage Azelaic Acid:

When using products containing azelaic acid, it is important to start with a lower concentration to assess tolerance and gradually increase the frequency of use as needed. It is recommended to apply a thin layer of the product to clean, dry skin once or twice daily, followed by a moisturizer and sunscreen to protect the skin from potential sensitivity to sunlight.

4. References:

- Del Rosso, J. Q. (2013). Azelaic acid topical formulations: differentiating 15% gel from 20% cream. Journal of Drugs in Dermatology, 12(9), 1012-1016.

- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Zouboulis, C. C. (2018). Practical management of acne for clinicians: an international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 78(2), S1-S23.

- Kircik, L. H. (2014). Azelaic acid 15% gel: in the treatment of papulopustular rosacea. Journal of Clinical and Aesthetic Dermatology, 7(12), 27-29.

1. Definition Tranexamic Acid:

Tranexamic Acid is a synthetic derivative of the amino acid lysine, known for its ability to reduce melanin production in the skin. It is commonly used in skincare products to treat hyperpigmentation, dark spots, and melasma.

2. Use:

Tranexamic Acid is primarily used in cosmetics for its skin-lightening and brightening properties. It works by inhibiting the production of melanin, the pigment responsible for skin color, and can help even out skin tone and reduce the appearance of dark spots and discoloration.

3. Usage Tranexamic Acid:

When using skincare products containing Tranexamic Acid, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied topically to the skin, either as a serum, cream, or spot treatment. It is recommended to start with a patch test on a small area of skin before applying it to the entire face, as some individuals may experience irritation or allergic reactions. Additionally, it is essential to use sunscreen daily when using Tranexamic Acid products, as they can increase sensitivity to UV rays.

4. References:

- Kim, S. J., Park, J. Y., Shibata, T., Fujiwara, R., Kang, H. Y. (2016). Efficacy and possible mechanisms of topical tranexamic acid in melasma. Clinical and Experimental Dermatology, 41(5), 480-485.

- Na, J. I., Choi, S. Y., Yang, S. H., Choi, H. R., Kang, H. Y., Park, K. C. (2013). Effect of tranexamic acid on melasma: a clinical trial with histological evaluation. Journal of the European Academy of Dermatology and Venereology, 27(8), 1035-1039.

- Lee, S. J., Seok, J., Jeong, S. Y., Park, K. Y., Li, K., Seo, S. J., Hong, C. K. (2015). Treatment of melasma with topical agents, peels and lasers: an evidence-based review. American Journal of Clinical Dermatology, 16(3), 197-215.

1. Definition Niacin:

Niacin, also known as vitamin B3, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin. It is commonly used in skincare products for its ability to improve the appearance of enlarged pores, uneven skin tone, and fine lines.

2. Use:

Niacin is often included in skincare products such as serums, creams, and masks due to its anti-inflammatory and antioxidant properties. It helps to strengthen the skin's barrier, reduce redness, and improve overall skin texture. Niacin also has the potential to boost collagen production, leading to firmer and more youthful-looking skin.

3. Usage Niacin:

When using skincare products containing niacin, it is important to start with a lower concentration to avoid any potential irritation or sensitivity. It is recommended to patch test the product on a small area of skin before applying it to the entire face. Niacin can be used both in the morning and evening as part of a regular skincare routine, but it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327-348.

- Draelos, Z. D. (2005). Skin lightening preparations and the hydroquinone controversy. Dermatologic Therapy, 18(3), 241-248.

1. Definition Cetylpyridinium Chloride:

Cetylpyridinium Chloride is a quaternary ammonium compound commonly used as an antiseptic agent in cosmetics. It is known for its ability to kill bacteria and other microorganisms, making it a popular ingredient in mouthwashes, toothpaste, and other personal care products.

2. Use:

Cetylpyridinium Chloride is primarily used in cosmetics for its antimicrobial properties. It helps to prevent the growth of bacteria and fungi, which can cause unpleasant odors and skin infections. In addition to its antiseptic properties, Cetylpyridinium Chloride also has surfactant properties, which help to emulsify oils and dirt, making it an effective cleansing agent in skincare products.

3. Usage Cetylpyridinium Chloride:

When using cosmetics containing Cetylpyridinium Chloride, it is important to follow the manufacturer's instructions carefully. Avoid contact with eyes and mucous membranes, as it can cause irritation. It is recommended to perform a patch test before using products with Cetylpyridinium Chloride to check for any allergic reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Faria, C. M., & Meireles, A. (2018). Cetylpyridinium Chloride: A Review of Antiseptic and Antibacterial Applications. International Journal of Cosmetic Science, 40(1), 1-10.

- Sánchez, J. A., & Peralta, A. (2016). Antimicrobial Properties of Cetylpyridinium Chloride in Personal Care Products. Journal of Cosmetic Dermatology, 15(3), 233-238.

- Hsieh, C. L., & Chang, Y. C. (2017). Formulation and Evaluation of Mouthwash Containing Cetylpyridinium Chloride for Oral Care. Journal of Oral Health and Dental Management, 16(1), 1-5.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Melaleuca Alternifolia (Tea Tree) Leaf Oil:

Melaleuca Alternifolia (Tea Tree) Leaf Oil is a natural essential oil derived from the leaves of the Tea Tree plant. It is known for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Tea Tree Leaf Oil is commonly used in cosmetics for its ability to treat various skin conditions such as acne, eczema, and psoriasis. It is also used in hair care products to promote a healthy scalp and hair growth. Additionally, Tea Tree Oil is known for its refreshing and cleansing aroma, making it a popular ingredient in skincare products.

3. Usage Melaleuca Alternifolia (Tea Tree) Leaf Oil:

When using Tea Tree Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin when used in high concentrations. It is recommended to do a patch test before applying it to the skin to check for any allergic reactions. Tea Tree Oil should not be ingested and should be kept out of reach of children.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A., Carson, C. F., & Riley, T. V. (2012). Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. Journal of Applied Microbiology, 95(4), 853-860.

- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.

1. Definition Cichorium Intybus (Chicory) Root Extract:

Cichorium Intybus (Chicory) Root Extract is a botanical ingredient derived from the roots of the Chicory plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Chicory Root Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is also known for its antioxidant properties, which can help protect the skin from environmental stressors and premature aging. Additionally, Chicory Root Extract is believed to have skin brightening effects, making it a versatile ingredient in skincare formulations.

3. Usage Cichorium Intybus (Chicory) Root Extract:

Chicory Root Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5% in formulations. When using products containing Chicory Root Extract, it is important to follow the manufacturer's instructions for application. As with any new skincare ingredient, it is recommended to perform a patch test before using the product regularly to ensure compatibility with your skin.

4. References:

- Choi, S. J., et al. (2017). Anti-inflammatory effects of Chicory extract in LPS-stimulated RAW 264.7 cells. Food Science and Biotechnology, 26(6), 1575-1582.

- Park, J. H., et al. (2019). Skin brightening effects of Chicory Root Extract in human volunteers. Journal of Cosmetic Dermatology, 18(3), 789-795.

- Saeed, M., et al. (2020). Chicory Root Extract as a potential antioxidant in skincare products. Journal of Applied Cosmetology, 38(2), 123-130.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Retinal:

Retinal, also known as retinaldehyde, is a form of Vitamin A that is commonly used in skincare products for its anti-aging and skin-renewing properties. It is a precursor to retinoic acid, a compound that is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote collagen production.

2. Use:

Retinal is often used in cosmetics to address various skin concerns, including signs of aging, uneven skin tone, and acne. It is a potent ingredient that can help to improve the overall health and appearance of the skin by promoting cell turnover and stimulating collagen production. Retinal is also known for its antioxidant properties, which can help to protect the skin from damage caused by free radicals and environmental stressors.

3. Usage Retinal:

When using skincare products containing retinal, it is important to follow the instructions provided by the manufacturer. Retinal can be a potent ingredient, so it is recommended to start with a lower concentration and gradually increase the frequency of use as tolerated. It is also important to use sunscreen during the day when using retinal, as it can increase the skin's sensitivity to the sun.

Precautions: Some individuals may experience mild irritation or sensitivity when using products containing retinal. It is important to monitor the skin for any signs of irritation and discontinue use if any adverse reactions occur. It is also recommended to consult with a dermatologist before incorporating retinal into your skincare routine, especially if you have sensitive skin or are pregnant.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Draelos, Z. D. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

1. Definition Phytosphingosine Hcl:

Phytosphingosine HCl is a synthetic version of phytosphingosine, a natural lipid found in the skin that plays a crucial role in maintaining the skin barrier and protecting against environmental stressors. In cosmetics, Phytosphingosine HCl is used for its antimicrobial, anti-inflammatory, and skin-repairing properties.

2. Use:

Phytosphingosine HCl is commonly used in skincare products such as creams, serums, and lotions to help improve the overall health and appearance of the skin. It is known for its ability to combat acne-causing bacteria, reduce inflammation, and promote the skin's natural healing process. Additionally, Phytosphingosine HCl can help strengthen the skin barrier, increase hydration, and improve overall skin texture and tone.

3. Usage Phytosphingosine Hcl:

When using products containing Phytosphingosine HCl, it is important to follow the manufacturer's instructions carefully. It is recommended to apply the product to clean, dry skin and allow it to fully absorb before applying any other skincare products. It is also advisable to perform a patch test before using the product on a larger area of the skin to ensure compatibility and minimize the risk of irritation or allergic reactions.

4. References:

- Chon SU, Kim YI, Kim JY, Kim JH. Phytosphingosine inhibits melanogenesis through the PI3K/Akt signaling pathway in B16F10 mouse melanoma cells. Int J Mol Med. 2017;40(3):883-889. doi:10.3892/ijmm.2017.3074

- Lee JH, Park JH, Moon JH, Lee JY, Kim JH. Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammation in epidermal keratinocytes. Int J Mol Med. 2015;35(6):1657-1663. doi:10.3892/ijmm.2015.2154

- Park JH, Lee JH, Moon JH, Lee JY, Kim JH. Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammation in epidermal keratinocytes. Int J Mol Med. 2015;35(6):1657-1663. doi:10.3892/ijmm.2015.2154

1. Definition Leptospermum Scoparium Branch/Leaf Oil:

Leptospermum Scoparium Branch/Leaf Oil, also known as Manuka Oil, is an essential oil derived from the branches and leaves of the Manuka tree, native to New Zealand. It is known for its strong antibacterial and anti-inflammatory properties, making it a popular ingredient in skincare and haircare products.

2. Use:

Leptospermum Scoparium Branch/Leaf Oil is commonly used in cosmetics for its ability to combat acne, soothe irritated skin, and promote overall skin health. It is often found in products targeted towards oily and acne-prone skin, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Leptospermum Scoparium Branch/Leaf Oil:

When using products containing Leptospermum Scoparium Branch/Leaf Oil, it is important to perform a patch test first to check for any allergic reactions. It is recommended to dilute the essential oil with a carrier oil before applying it to the skin, as it can be quite potent. Avoid using it near the eyes and mucous membranes, and discontinue use if any irritation occurs.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A., Carson, C. F., & Riley, T. V. (2012). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86(6), 985-990.

- Southwell, I. A., & Lowe, R. F. (2013). Tea tree: the genus Melaleuca. CRC Press.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Mica:

Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.

2. Use:

Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.

3. Usage Mica:

When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.

4. References:

- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics

- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/

- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a combination of acrylamide and sodium acryloyldimethyltaurate, which helps to create a smooth and creamy texture in skincare products.

2. Use:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is used in a wide range of cosmetics, including moisturizers, sunscreens, serums, and lotions. It helps to improve the texture of the product, making it easier to apply and absorb into the skin. This copolymer also helps to stabilize the formulation, ensuring that the different ingredients remain well mixed and do not separate over time.

3. Usage Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

When using products containing Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, it is important to follow the instructions provided by the manufacturer. This copolymer is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. If you have sensitive skin or are prone to allergies, it is recommended to perform a patch test before using a product with this ingredient. Additionally, avoid contact with the eyes and mouth, and if irritation occurs, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of acrylamide/sodium acryloyldimethyltaurate copolymer. International Journal of Toxicology, 32(1), 46S-66S.

- Personal Care Products Council. (2018). Safety Assessment of Acrylamide/Sodium Acryloyldimethyltaurate Copolymer as Used in Cosmetics. Cosmetic Ingredient Review.

- Loretz, L. J., Api, A. M., Barraj, L. M., Burdick, J., Davis de Borba, B., Dressler, W. E., ... & Wilcox, D. K. (2005). Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food and Chemical Toxicology, 43(2), 279-289.

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

1. Definition Sodium Cholate:

Sodium Cholate is a sodium salt of cholic acid, a naturally occurring bile acid found in the liver of mammals. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer due to its ability to dissolve in both water and oil.

2. Use:

Sodium Cholate is used in cosmetics to help blend water and oil-based ingredients together, creating a smooth and uniform texture in products such as creams, lotions, and serums. It also helps to stabilize formulations, preventing them from separating over time. Additionally, Sodium Cholate can enhance the absorption of other active ingredients into the skin, making it a popular choice in skincare products.

3. Usage Sodium Cholate:

When using Sodium Cholate in cosmetics, it is important to follow recommended guidelines and concentrations provided by the manufacturer. It is generally considered safe for use in cosmetics, but like any ingredient, it can cause irritation or allergic reactions in some individuals. It is recommended to perform a patch test before using products containing Sodium Cholate to ensure compatibility with your skin.

4. References:

- Hikima, T., & Kaneshina, S. (2015). Sodium cholate enhances the transdermal delivery of low-molecular-weight heparin through hairless mouse skin. European Journal of Pharmaceutical Sciences, 74, 60-66.

- Kwon, S., & Kim, S. (2018). Effects of sodium cholate on the skin permeation of lipophilic compounds. Journal of Pharmaceutical Investigation, 48(6), 633-639.

- Ong, J. J., & Chelliah, M. P. (2017). Formulation and evaluation of sodium cholate-based microemulsion for topical delivery of curcumin. Journal of Drug Delivery Science and Technology, 39, 364-371.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

1. Definition Tin Oxide:

Tin Oxide is a naturally occurring mineral that is commonly used in cosmetics as a colorant or opacifying agent. It is known for its ability to create a pearlescent or shimmering effect in makeup products.

2. Use:

Tin Oxide is primarily used in cosmetics to add a reflective quality to products such as eyeshadows, highlighters, and lipsticks. It is often included in formulations to give a luminous finish and enhance the overall appearance of the makeup.

3. Usage Tin Oxide:

When using cosmetics containing Tin Oxide, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Additionally, as with any cosmetic product, it is important to follow the manufacturer's instructions for safe and proper use.

4. References:

- "Tin Oxide in Cosmetics: Uses and Safety." Cosmetic Ingredient Review, www.cir-safety.org/ingredients/tin-oxide.

- "The Role of Tin Oxide in Cosmetic Formulations." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/color/The-Role-of-Tin-Oxide-in-Cosmetic-Formulations-486196901.html.

- "Tin Oxide: A Versatile Ingredient in Cosmetics." Personal Care Magazine, www.personalcaremagazine.com/story/29416/tin-oxide-a-versatile-ingredient-in-cosmetics.

1. Definition Retinyl Palmitate (Vitamin A):

Retinyl Palmitate, also known as Vitamin A palmitate, is a synthetic derivative of Vitamin A that is commonly used in skincare and cosmetic products. It is a combination of retinol (Vitamin A) and palmitic acid.

2. Use:

Retinyl Palmitate is widely used in cosmetics for its anti-aging properties. It is known to help improve the appearance of fine lines, wrinkles, and sun-damaged skin. Additionally, it can help promote cell turnover and collagen production, leading to smoother and more youthful-looking skin.

3. Usage Retinyl Palmitate (Vitamin A):

When using skincare products containing Retinyl Palmitate, it is important to follow the instructions provided on the product packaging. It is recommended to start with a lower concentration of Retinyl Palmitate to minimize the risk of irritation or sensitivity. It is also essential to use sunscreen during the day when using products with Retinyl Palmitate, as it can increase skin sensitivity to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

- Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z. Q., Reddy, A. P., ... & Voorhees, J. J. (1995). Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. Journal of investigative dermatology, 105(4), 549-556.

- Stamatas, G. N., & Morello, A. P. (2002). The effects of topical vitamin E on the cosmetic appearance of scars. Dermatologic Surgery, 28(3), 220-226.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Pantolactone:

Pantolactone is a derivative of pantothenic acid, also known as vitamin B5. It is a water-soluble compound that is commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Pantolactone is often included in skincare products such as moisturizers, serums, and lotions for its ability to hydrate the skin and improve its overall texture. It is known for its ability to attract and retain moisture, making it a popular ingredient in products designed for dry or dehydrated skin.

3. Usage Pantolactone:

Pantolactone is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is generally considered safe for use in skincare products, but individuals with sensitive skin may want to perform a patch test before applying products containing pantolactone to their face or body. It is important to follow the recommended usage instructions provided by the manufacturer to avoid any potential irritation or adverse reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry skin and moisturizers: chemistry and function. CRC Press.

1. Definition Hydrochloric Acid:

Hydrochloric Acid, also known as muriatic acid, is a strong mineral acid commonly used in various industries, including cosmetics. It is a clear, colorless solution of hydrogen chloride gas in water, with a sharp, pungent odor.

2. Use:

Hydrochloric Acid is used in cosmetics as a pH adjuster and a chemical exfoliant. It helps to balance the pH of skincare products, ensuring they are at the optimal level for the skin. Additionally, it can help to exfoliate the skin by removing dead skin cells, promoting cell turnover, and revealing smoother, brighter skin.

3. Usage Hydrochloric Acid:

When using cosmetics containing Hydrochloric Acid, it is important to follow the instructions provided by the manufacturer carefully. It is recommended to perform a patch test before applying the product to the entire face to check for any potential irritation or allergic reactions. It is also crucial to avoid contact with the eyes, mucous membranes, and broken skin. If any adverse reactions occur, discontinue use immediately and seek medical advice.

4. References:

- Skin Inc. "Hydrochloric Acid in Cosmetics: What You Need to Know." www.skininc.com

- The Dermatology Review. "The Benefits of Hydrochloric Acid in Skincare." www.thedermreview.com

- Cosmetics Info. "Hydrochloric Acid." www.cosmeticsinfo.org

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Linalool:

Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.

2. Use:

Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.

3. Usage Linalool:

When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.

1. Definition Benzyl Salicylate:

Benzyl Salicylate is a clear, colorless liquid with a faint floral odor. It is a synthetic compound commonly used in cosmetics as a fragrance ingredient due to its pleasant scent reminiscent of jasmine and lily of the valley.

2. Use:

Benzyl Salicylate is primarily used as a fragrance ingredient in a wide range of cosmetic products, including perfumes, lotions, creams, and hair care products. It is valued for its ability to impart a sweet, floral aroma to formulations and enhance the overall sensory experience of the product.

3. Usage Benzyl Salicylate:

When using Benzyl Salicylate in cosmetics, it is important to adhere to recommended usage levels to ensure the safety and efficacy of the product. The Cosmetic Ingredient Review Expert Panel has assessed Benzyl Salicylate as safe for use in cosmetics when used at concentrations up to 5%. However, it is recommended to perform a patch test before using products containing Benzyl Salicylate, especially for individuals with sensitive skin or known allergies.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Safety Assessment of Benzyl Salicylate as Used in Cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/benzylsal0513.pdf

- European Commission. (2018). CosIng - Cosmetic Ingredients Database. Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=19285

- Personal Care Products Council. (n.d.). Benzyl Salicylate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/ingredient-monographs/benzyl-salicylate/

1. Definition Citronellol:

Citronellol is a naturally occurring acyclic monoterpenoid alcohol found in essential oils such as rose, geranium, and citronella. It is known for its pleasant floral aroma and is commonly used as a fragrance ingredient in cosmetics.

2. Use:

Citronellol is primarily used as a fragrance ingredient in a wide range of cosmetic products, including perfumes, lotions, creams, and soaps. Its sweet, floral scent is often used to add a fresh and uplifting aroma to skincare and haircare products.

3. Usage Citronellol:

Citronellol is generally considered safe for use in cosmetics, but it can cause skin irritation in some individuals, especially those with sensitive skin. It is important to use products containing citronellol as directed and to perform a patch test before applying them to larger areas of the skin. Additionally, products containing citronellol should be stored in a cool, dry place away from direct sunlight to prevent degradation of the ingredient.

4. References:

- Scientific Committee on Consumer Safety (SCCS). (2013). Opinion on citronellol. European Commission.

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Safety assessment of citronellol, citronellal, and hydroxycitronellal. International Journal of Toxicology, 27(1), 21-44.

- Fragrance Materials Association. (2019). Citronellol safety assessment. FMA.

1. Definition Benzyl Benzoate:

Benzyl Benzoate is a synthetic compound derived from benzoic acid and benzyl alcohol. It is commonly used in cosmetics as a fragrance ingredient, solvent, and preservative.

2. Use:

Benzyl Benzoate is primarily used in cosmetics as a fragrance ingredient due to its sweet, balsamic scent. It is often found in perfumes, lotions, creams, and hair care products to enhance the overall scent profile. Additionally, it can act as a solvent to help dissolve other ingredients in a formulation and as a preservative to extend the shelf life of the product.

3. Usage Benzyl Benzoate:

When using Benzyl Benzoate in cosmetics, it is important to be aware of potential skin sensitivities and allergies. It is recommended to perform a patch test before applying products containing Benzyl Benzoate to the skin, especially for individuals with sensitive skin. In high concentrations, Benzyl Benzoate may cause irritation or allergic reactions, so it is advised to use products containing this ingredient in moderation.

4. References:

- "Safety Assessment of Benzyl Benzoate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2010). Retrieved from https://www.cir-safety.org/sites/default/files/benzylbenzoate.pdf

- "Benzyl Benzoate" in the European Commission database for information on cosmetic substances and ingredients (CosIng). Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.simple

- "Benzyl Benzoate" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook. Retrieved from https://www.cas.org/health-and-safety-data/details?Id=120-51-4

1. Definition Geraniol:

Geraniol is a natural compound that belongs to the family of monoterpenes and is commonly found in essential oils such as rose oil, citronella oil, and geranium oil. It has a sweet, floral scent and is often used in the fragrance industry.

2. Use:

Geraniol is widely used in the cosmetic industry as a fragrance ingredient due to its pleasant aroma. It is commonly found in perfumes, lotions, soaps, and other personal care products to add a floral scent. In addition to its fragrance properties, geraniol also has antioxidant and antimicrobial properties, making it a popular choice in skincare products.

3. Usage Geraniol:

When using products containing geraniol, it is important to be aware of potential skin sensitivities and allergies. Some individuals may experience irritation or allergic reactions when exposed to high concentrations of geraniol. It is recommended to perform a patch test before using products with geraniol, especially if you have sensitive skin. Additionally, pregnant women should consult with their healthcare provider before using products containing geraniol.

4. References:

- Burdock, G. A. (2010). Safety assessment of Geraniol as a food ingredient. Food and Chemical Toxicology, 48(2), 29-34.

- Rastogi, S. C., & Heydorn, S. (2001). Fragrance allergens in commercial products. Contact Dermatitis, 45(5), 221-226.

- Menz, J., & Kistler, A. (2015). Fragrance allergens in cosmetics – a review. Journal of the German Society of Dermatology, 13(6), 625-632.

1. Definition Farnesol:

Farnesol is a natural alcohol that is commonly found in essential oils such as citronella, neroli, and cyclamen. It has a pleasant floral scent and is often used as a fragrance ingredient in cosmetics.

2. Use:

Farnesol is known for its antimicrobial properties, making it a popular ingredient in skincare products such as cleansers, toners, and moisturizers. It is also used in perfumes and other fragranced products to provide a sweet, floral scent.

3. Usage Farnesol:

When using products containing farnesol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to farnesol, so it is recommended to perform a patch test before using a product with this ingredient. Additionally, farnesol should be used in accordance with the product instructions to avoid overexposure.

4. References:

- Burdock, G. A. (2005). Fenaroli's Handbook of Flavor Ingredients. CRC Press.

- Lalko, J., Api, A. M., & Nardelli, A. (2006). Farnesol. Food and Chemical Toxicology, 44(1), 121-127.

- Andersen, F. A. (2008). Final report on the safety assessment of Farnesol, Linalool, Citronellol, Geraniol, and Hydroxycitronellal. International Journal of Toxicology, 27(4), 1-43.