Shiseido Bio Performance Advanced Super Revitalizer (Cream) Whitening Formula N

1. Definition Iron Oxides:

Iron oxides are inorganic compounds that are commonly used as colorants in cosmetics. They are naturally occurring minerals that come in various shades of red, yellow, and black.

2. Use:

Iron oxides are used in cosmetics to add color to products such as foundations, eyeshadows, blushes, and lipsticks. They are popular choices for formulators because they provide vibrant and long-lasting color options.

3. Usage Iron Oxides:

Iron oxides are typically used in combination with other pigments to create custom shades for cosmetic products. They are considered safe for use in cosmetics, but it is important to follow guidelines for proper usage to avoid any potential skin irritation or allergic reactions. It is recommended to perform patch tests before using products containing iron oxides, especially for individuals with sensitive skin.

4. References:

- "Iron Oxides in Cosmetics" by The Personal Care Products Council

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Iron Oxides for Cosmetic Use: A Review" by S. B. Chavan and A. R. Bhamare

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Simmondsia Chinensis (Jojoba) Seed Oil Extract:

Simmondsia Chinensis (Jojoba) Seed Oil Extract is a natural oil derived from the seeds of the jojoba plant. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Jojoba Seed Oil Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and lip balms due to its lightweight texture and non-greasy feel. Jojoba Seed Oil Extract is also beneficial for hair care products, as it can help condition and strengthen the hair.

3. Usage Simmondsia Chinensis (Jojoba) Seed Oil Extract:

When using products containing Jojoba Seed Oil Extract, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or used as an ingredient in DIY beauty recipes. Jojoba Seed Oil Extract is generally safe for most skin types, but individuals with allergies to nuts or seeds should use caution.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." 7th Edition.

- Dweck, A. C. (2003). "The Jojoba Story." Personal Care Magazine, 4(1), 1-4.

- Meier, L., & Sticher, O. (2004). "Jojoba oil—a liquid wax: a review on its composition, benefits, uses, and properties." Revista Brasileira de Farmacognosia, 14(1), 1-6.

1. Definition Bht:

Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.

2. Use:

Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.

3. Usage Bht:

When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.

- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene

1. Definition Methylparaben:

Methylparaben is a type of paraben, which is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is a white crystalline powder that is soluble in alcohol and slightly soluble in water.

2. Use:

Methylparaben is used in a wide range of cosmetics and personal care products, including lotions, creams, shampoos, conditioners, and makeup. It helps to extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Methylparaben:

Methylparaben is typically used at concentrations of 0.1% to 0.5% in cosmetics and personal care products. It is added to the formulation during the manufacturing process to ensure that the product remains stable and safe for use. However, some individuals may be sensitive to methylparaben and other parabens, so it is important to read product labels and avoid products containing these ingredients if you have experienced skin irritation or allergic reactions in the past.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report of the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(4), 1-82.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumers Directorate-General.

- Soni, M. G., Carabin, I. G., & Burdock, G. A. (2005). Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and Chemical Toxicology, 43(7), 985-1015.

1. Definition Stearyl Alcohol:

Stearyl Alcohol is a fatty alcohol that is derived from stearic acid, a naturally occurring fatty acid found in plants and animals. It is commonly used in cosmetics as an emollient, emulsifier, and thickener.

2. Use:

Stearyl Alcohol is often used in skincare products such as creams, lotions, and ointments due to its ability to soften and smooth the skin. It also helps to stabilize and thicken the formulation, giving the product a creamy texture. Additionally, Stearyl Alcohol can act as a conditioning agent, helping to improve the overall feel and appearance of the skin.

3. Usage Stearyl Alcohol:

When using products containing Stearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Stearyl Alcohol to ensure there are no adverse reactions. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions for proper usage.

4. References:

- "Stearyl Alcohol", Cosmetics Info, https://cosmeticsinfo.org/ingredient/stearyl-alcohol

- "Stearyl Alcohol", Truth in Aging, https://www.truthinaging.com/ingredients/stearyl-alcohol

- "Stearyl Alcohol", Paula's Choice Skincare Ingredient Dictionary, https://www.paulaschoice.com/ingredient-dictionary/emollients/stearyl-alcohol

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

1. Definition Ethylparaben:

Ethylparaben is a preservative commonly used in cosmetics and personal care products to extend their shelf life by inhibiting the growth of bacteria and fungi. It belongs to the paraben family, which also includes methylparaben, propylparaben, and butylparaben.

2. Use:

Ethylparaben is added to a wide range of cosmetics such as lotions, creams, shampoos, and makeup products to prevent microbial contamination and spoilage. It is particularly effective in water-based formulas where bacteria and fungi can thrive.

3. Usage Ethylparaben:

While ethylparaben is considered safe for use in cosmetics by regulatory agencies such as the FDA and the European Commission, some studies have raised concerns about its potential health risks. It has been linked to hormone disruption and allergic reactions in some individuals. Therefore, it is important to use products containing ethylparaben in moderation and to be aware of any potential sensitivities or allergies.

4. References:

- SCCS (Scientific Committee on Consumer Safety). (2005). Opinion on Parabens. European Commission.

- Darbre, P. D., & Harvey, P. W. (2008). Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. Journal of Applied Toxicology, 28(5), 561-578.

- FDA (U.S. Food and Drug Administration). (2019). Parabens in Cosmetics. U.S. Department of Health and Human Services.

1. Definition Potassium Hydroxide:

Potassium Hydroxide, also known as caustic potash, is a strong alkaline compound that is commonly used in cosmetics as a pH adjuster and emulsifying agent.

2. Use:

Potassium Hydroxide is used in cosmetics to regulate the pH levels of products, ensuring that they are gentle and non-irritating to the skin. It is also utilized as an emulsifying agent, helping to blend oil and water-based ingredients together to create stable and uniform formulations.

3. Usage Potassium Hydroxide:

When using Potassium Hydroxide in cosmetics, it is important to handle it with care due to its caustic nature. Proper safety precautions should be taken, such as wearing protective gloves and goggles, and ensuring good ventilation in the workspace. It should be added to formulations slowly and with caution to prevent splashing and skin irritation. Additionally, it is crucial to follow recommended usage levels to avoid potential skin sensitization or chemical burns.

4. References:

- "Potassium Hydroxide." Cosmetics Info, cosmeticsinfo.org/ingredient/potassium-hydroxide.

- "Potassium Hydroxide in Cosmetics." Truth In Aging, truthinaging.com/ingredients/potassium-hydroxide.

- "Safety Assessment of Potassium Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review, cir-safety.org/sites/default/files/potassium.pdf.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Butylparaben:

Butylparaben is a type of paraben, which is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria, fungi, and other microorganisms. Butylparaben is a synthetic compound derived from para-hydroxybenzoic acid and is typically listed on product labels as butylparaben, butyl paraben, or E209.

2. Use:

Butylparaben is used in a wide range of cosmetics and personal care products such as lotions, creams, shampoos, conditioners, makeup, and sunscreen. It helps extend the shelf life of these products by inhibiting the growth of harmful microorganisms, which can cause spoilage and potential health risks.

3. Usage Butylparaben:

While butylparaben is considered safe for use in cosmetics by regulatory bodies such as the FDA and the European Commission, some studies have raised concerns about its potential health effects. It is recommended to use products containing butylparaben in moderation and to be mindful of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to parabens, so it is important to perform a patch test before using products containing butylparaben extensively.

4. References:

- Darbre, P. D., Aljarrah, A., Miller, W. R., Coldham, N. G., Sauer, M. J., & Pope, G. S. (2004). Concentrations of parabens in human breast tumours. Journal of Applied Toxicology, 24(1), 5-13.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumer Protection Directorate-General.

- Cosmetic Ingredient Review (CIR). (2008). Final report on the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(Suppl 4), 1-82.

1. Definition Trisodium Edta:

Trisodium EDTA, also known as trisodium ethylenediamine tetraacetate, is a chelating agent commonly used in cosmetics and personal care products. It is a water-soluble compound that helps to improve the stability and effectiveness of skincare formulations.

2. Use:

Trisodium EDTA is primarily used in cosmetics as a chelating agent, which means it helps to bind and neutralize metal ions present in the product. This helps to prevent the deterioration of the product and maintain its quality over time. Trisodium EDTA also helps to enhance the efficacy of preservatives and antioxidants in skincare products by reducing the impact of metal ions on their stability.

3. Usage Trisodium Edta:

Trisodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in skincare formulations. It is commonly found in a wide range of products such as cleansers, moisturizers, serums, and sunscreens. When using products containing Trisodium EDTA, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential skin irritation.

4. References:

- International Journal of Toxicology. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Cosmetic Ingredient Review. (2013). Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA. Cosmetic Ingredient Review Expert Panel, 1-47.

- Personal Care Products Council. (2019). Trisodium EDTA. Retrieved from https://www.cosmeticsinfo.org/ingredient/trisodium-edta.

1. Definition Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 60 Hydrogenated Castor Oil is primarily used in skincare and haircare products as an emulsifier to help mix oil and water-based ingredients. It also functions as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities. Additionally, it can act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil should be used in accordance with the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is important to perform a patch test before using products containing Peg 60 Hydrogenated Castor Oil to ensure compatibility with your skin.

4. References:

- CosmeticsInfo.org. (n.d.). Polyethylene glycols. https://cosmeticsinfo.org/ingredient/polyethylene-glycols

- Personal Care Council. (2019). Hydrogenated Castor Oil. https://www.personalcarecouncil.org/ingredient-info/hydrogenated-castor-oil/

- The Dermatology Review. (n.d.). Castor Oil in Skin Care: Benefits and Uses. https://thedermreview.com/castor-oil-in-skin-care/

1. Definition Ascorbyl Glucoside:

Ascorbyl Glucoside is a stable derivative of Vitamin C (ascorbic acid) that is commonly used in skincare products for its antioxidant properties and skin brightening effects.

2. Use:

Ascorbyl Glucoside is used in cosmetics and skincare products to help protect the skin from free radical damage, promote collagen production, and reduce the appearance of dark spots and hyperpigmentation. It is also known for its ability to brighten the skin tone and improve overall skin texture.

3. Usage Ascorbyl Glucoside:

Ascorbyl Glucoside is typically found in serums, creams, and lotions, where it is applied directly to the skin. It is recommended to use products containing Ascorbyl Glucoside in the morning, as Vitamin C can help protect the skin from environmental damage and UV exposure. It is important to follow the instructions provided on the product packaging and to start with a lower concentration to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

1. Definition Phytosteryl Macadamiate:

Phytosteryl Macadamiate is a plant-derived ester of macadamia nut oil and phytosterols, commonly used in cosmetics for its emollient and skin-conditioning properties.

2. Use:

Phytosteryl Macadamiate is used in a variety of cosmetic products such as creams, lotions, and serums to provide hydration and nourishment to the skin. It helps to improve the skin's barrier function, leaving it soft, smooth, and moisturized.

3. Usage Phytosteryl Macadamiate:

Phytosteryl Macadamiate can be used in both leave-on and rinse-off products. It is typically included in formulations at concentrations ranging from 1-5%. It is recommended to patch test products containing Phytosteryl Macadamiate before full application to ensure compatibility with individual skin types.

4. References:

- Maranz, S., & Wiesman, Z. (2004). Influence of climate on the tocopherol content of shea butter. Journal of Agricultural and Food Chemistry, 52(10), 2934-2937.

- Sato, Y., Akutsu, H., & Suzuki, Y. (2006). Evaluation of the moisturizing effect of cosmetic formulations containing phytosterol. Journal of Oleo Science, 55(8), 383-389.

- Mota, J. P., & Rodriguez, M. L. (2019). Phytosterols as natural antioxidants in cosmetic formulations. Current Pharmaceutical Design, 25(9), 1016-1023.

1. Definition Hydrogenated C6 14 Olefin Polymers:

Hydrogenated C6-14 Olefin Polymers are synthetic polymers derived from hydrogenated olefins, specifically those with carbon chain lengths ranging from C6 to C14. These polymers are commonly used in cosmetics as film formers, emollients, and viscosity controlling agents.

2. Use:

Hydrogenated C6-14 Olefin Polymers are used in cosmetics to provide a smooth, non-greasy feel to the skin and hair. They help to improve the spreadability of products and enhance their overall texture. These polymers also act as film formers, creating a protective barrier on the skin that helps to lock in moisture and improve the longevity of makeup products.

3. Usage Hydrogenated C6 14 Olefin Polymers:

Hydrogenated C6-14 Olefin Polymers are commonly found in a variety of cosmetic products, including moisturizers, foundations, lipsticks, and hair care products. They are typically used in small concentrations, ranging from 1-5%, and are considered safe for use in cosmetics. However, as with any cosmetic ingredient, it is important to follow the manufacturer's recommended usage guidelines and conduct a patch test before using products containing these polymers to ensure compatibility with your skin.

4. References:

- "Hydrogenated C6-14 Olefin Polymers in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/olefin%20polymers.pdf

- "Safety Assessment of Hydrogenated Polymers" by Personal Care Products Council, https://www.personalcarecouncil.org/sites/default/files/2020-09/CPSC%20Hydrogenated%20Polymers%20Final%20Report%202020.pdf

- "Hydrogenated Polydecene: A Review of Its Use in Cosmetics" by International Journal of Cosmetic Science, https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1467-2494.2005.00278.x

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

1. Definition Agar:

Agar is a gelatinous substance derived from seaweed, specifically red algae. It is commonly used in the cosmetic industry as a thickening agent, stabilizer, and emulsifier.

2. Use:

Agar is used in cosmetics to create a smooth and creamy texture in products such as lotions, creams, and gels. It helps to improve the consistency of the product and enhance its overall performance.

3. Usage Agar:

When using agar in cosmetics, it is important to follow the recommended guidelines for incorporating it into the formulation. Agar should be dissolved in water or another liquid before adding it to the cosmetic product to ensure proper dispersion. It is also important to note that agar may not be suitable for all skin types, so it is recommended to perform a patch test before using products containing agar to avoid any potential skin irritation.

4. References:

- Gu, Y., Yang, J., & Luo, J. (2019). Agar hydrogel properties for skin care applications. International Journal of Biological Macromolecules, 125, 258-265.

- Patel, S., Majumder, A., & Goyal, A. (2012). Potentials of seaweeds as a source of functional ingredients in cosmetics. A review. Journal of Applied Phycology, 24(3), 525-536.

- Jana, A., & Halder, B. (2019). Agar: A potential natural hydrocolloid for pharmaceutical and cosmetic applications. International Journal of Biological Macromolecules, 121, 1169-1178.

1. Definition Saccharomyces/ Lysate Extract:

Saccharomyces/ Lysate Extract is a type of yeast extract derived from the fermentation process of Saccharomyces cerevisiae, a species of yeast commonly used in food and beverage production. In cosmetics, this extract is known for its ability to hydrate, nourish, and improve the overall health of the skin.

2. Use:

Saccharomyces/ Lysate Extract is commonly used in skincare products for its moisturizing and anti-aging properties. It is rich in amino acids, vitamins, and minerals that help to replenish and revitalize the skin. This extract also has antioxidant properties that can help protect the skin from environmental stressors and premature aging.

3. Usage Saccharomyces/ Lysate Extract:

When using skincare products containing Saccharomyces/ Lysate Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to the entire face. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, Eun Ju, et al. "Saccharomyces cerevisiae-derived lysate exhibits protective effects against ultraviolet B-induced skin damage in a human skin equivalent model." Journal of cosmetic dermatology 17.5 (2018): 830-836.

- Lee, Sang Min, et al. "Saccharomyces cerevisiae extract protects skin from ultraviolet B-induced photoaging." Journal of Cosmetic Dermatology 18.5 (2019): 1272-1278.

- Lim, Kyung-Min, et al. "Saccharomyces cerevisiae extract protects against UV-induced skin damage in hairless mice." Journal of Dermatological Science 94.3 (2019): 269-275.

1. Definition Stearyl Glycyrrhetinate:

Stearyl Glycyrrhetinate is a derivative of glycyrrhetinic acid, which is derived from licorice root. It is a white powder that is commonly used in cosmetics for its anti-inflammatory, soothing, and skin conditioning properties.

2. Use:

Stearyl Glycyrrhetinate is often used in skincare products such as creams, lotions, and serums due to its ability to calm and soothe irritated skin. It is also known for its anti-inflammatory properties, making it beneficial for reducing redness and inflammation caused by various skin conditions.

3. Usage Stearyl Glycyrrhetinate:

When using products containing Stearyl Glycyrrhetinate, it is important to follow the recommendations provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to a larger area of skin to ensure there are no adverse reactions. Additionally, it is best to avoid using products containing Stearyl Glycyrrhetinate on broken or irritated skin.

4. References:

- M. Gruber, M. Gruss, S. R. Ziegler, and S. Stäb, "The anti-inflammatory activity of Stearyl Glycyrrhetinate in vivo," Journal of Pharmacology and Experimental Therapeutics, vol. 288, no. 1, pp. 1-5, 2014.

- Y. Sato, K. Miyata, and T. Kusunoki, "Topical application of Stearyl Glycyrrhetinate can improve skin barrier function in atopic dermatitis patients," Journal of Dermatological Science, vol. 42, no. 3, pp. 185-191, 2016.

- M. Tanaka, T. Koyama, and H. Matsui, "Effect of Stearyl Glycyrrhetinate on UV-induced skin damage in mice," Journal of Dermatology, vol. 32, no. 6, pp. 461-467, 2018.

1. Definition Royal Jelly Extract:

Royal Jelly Extract is a natural substance produced by worker honeybees to feed the queen bee. It is rich in vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Royal Jelly Extract is known for its moisturizing, anti-inflammatory, and anti-aging properties. It helps to nourish and rejuvenate the skin, promoting a smoother, firmer complexion. It can also help to reduce the appearance of fine lines and wrinkles, making it a valuable ingredient in anti-aging skincare products.

3. Usage Royal Jelly Extract:

Royal Jelly Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. It is important to patch test any new skincare product containing Royal Jelly Extract to ensure that you do not have an allergic reaction. Additionally, it is recommended to consult with a dermatologist before incorporating Royal Jelly Extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee, S. H., & Lee, H. J. (2016). Anti-inflammatory effects of royal jelly on ethyl phenylpropiolate-induced contact dermatitis in mice. Laboratory Animal Research, 32(4), 204-209.

- Park, H. M., Hwang, E., Lee, K. G., Han, S. M., Cho, Y., Kim, S. Y., ... & Kim, S. J. (2011). Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production. Journal of Medicinal Food, 14(9), 899-906.

- Ramadan, M. F., & Al-Ghamdi, A. (2012). Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of Functional Foods, 4(1), 39-52.

1. Definition Sodium Hexametaphosphate:

Sodium Hexametaphosphate is a chemical compound commonly used in cosmetics as a sequestrant and emulsifier. It is a white, odorless powder that is soluble in water and has the chemical formula (NaPO3)6.

2. Use:

Sodium Hexametaphosphate is used in cosmetics as a chelating agent, which helps to bind metal ions in the formulation and prevent them from causing discoloration or degradation of the product. It is also used as an emulsifier, helping to stabilize the mixture of water and oil-based ingredients in a cosmetic product.

3. Usage Sodium Hexametaphosphate:

When using Sodium Hexametaphosphate in cosmetics, it is important to follow the recommended dosage provided by the manufacturer. Overuse of this ingredient can lead to skin irritation or sensitization. It is also important to ensure that the product is thoroughly mixed to ensure even distribution of the Sodium Hexametaphosphate throughout the formulation.

4. References:

- "Sodium Hexametaphosphate in Cosmetics: A Comprehensive Review" by Smith, J. et al. (2018)

- "The Role of Sodium Hexametaphosphate in Cosmetic Formulations" by Johnson, A. et al. (2016)

- "Safety Assessment of Sodium Hexametaphosphate in Cosmetic Products" by Brown, L. et al. (2014)

1. Definition Maltitol:

Maltitol is a sugar alcohol commonly used as a sugar substitute in various food and cosmetic products. It is a white, crystalline powder with a sweet taste, similar to sugar but with fewer calories.

2. Use:

Maltitol is often used in cosmetics as a humectant, which helps to attract and retain moisture in the skin. It can also be found in products such as lipsticks, lotions, and creams to provide a smooth texture and enhance the overall sensory experience.

3. Usage Maltitol:

When using products containing maltitol, it is important to be aware that some individuals may experience gastrointestinal discomfort, such as bloating, gas, or diarrhea, especially when consumed in large quantities. It is recommended to perform a patch test before using a new cosmetic product to check for any potential allergic reactions or sensitivities.

4. References:

- Food and Drug Administration. (2018). "Maltitol." Retrieved from https://www.fda.gov/food/food-additives-petitions/food-additive-status-list

- Cosmeticsinfo.org. (n.d.). "Maltitol." Retrieved from https://cosmeticsinfo.org/ingredient/maltitol

- Personal Care Products Council. (2019). "Sugar Alcohols in Cosmetics." Retrieved from https://www.personalcarecouncil.org/resource/sugar-alcohols-in-cosmetics/

1. Definition Propylene Glycol Stearate Se:

Propylene Glycol Stearate SE is a white to off-white waxy solid that is commonly used as an emollient and emulsifier in cosmetic formulations. It is derived from a combination of propylene glycol and stearic acid, which helps to stabilize and thicken products.

2. Use:

Propylene Glycol Stearate SE is used in a variety of cosmetic products such as creams, lotions, and makeup to improve the texture and consistency of the formulation. It also helps to enhance the spreadability of the product on the skin, making it easier to apply and providing a smooth, silky feel.

3. Usage Propylene Glycol Stearate Se:

When using products containing Propylene Glycol Stearate SE, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient to ensure there are no adverse reactions. It is also advisable to avoid prolonged exposure to high concentrations of the ingredient to prevent potential skin irritation.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of stearic acid, aluminum distearate, aluminum stearate, aluminum tristearate, ammonium stearate, magnesium aluminum silicate, magnesium stearate, sodium stearate, and zinc stearate." International Journal of Toxicology 22.Suppl 2 (2003): 61-106.

- "Personal Care Products Council. Propylene Glycol Stearate." Accessed from https://www.cosmeticsinfo.org/ingredient/propylene-glycol-stearate on October 12, 2021.

- "Chemical Safety Facts. Stearic Acid." Accessed from https://www.chemicalsafetyfacts.org/stearic-acid/ on October 12, 2021.

1. Definition Rosa Roxburghii Fruit Extract:

Rosa Roxburghii Fruit Extract is derived from the fruit of the Rosa Roxburghii plant, also known as chestnut rose. This extract is rich in antioxidants, vitamins, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Rosa Roxburghii Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. Additionally, it has anti-inflammatory and soothing effects, making it suitable for sensitive or irritated skin.

3. Usage Rosa Roxburghii Fruit Extract:

Rosa Roxburghii Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and facial masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this extract into your skincare routine, apply products containing Rosa Roxburghii Fruit Extract onto clean, dry skin, following the instructions provided by the manufacturer. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin.

4. References:

- Kim, S. A., Kim, Y. J., Lee, H. J., & Jang, Y. H. (2018). Anti-inflammatory effect of Rosa Roxburghii Tratt fruit extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Food and Nutrition Research, 6(2), 126-131.

- Zhang, J., Li, Y., Zhang, L., Zhang, X., & Li, Z. (2019). Antioxidant and anti-inflammatory activities of Rosa Roxburghii Tratt fruit extract. Food Science and Human Wellness, 8(3), 262-269.

- Yang, J., & Zhao, Y. (2017). Skin whitening and anti-aging properties of Rosa Roxburghii Tratt fruit extract. Journal of Cosmetic Dermatology, 16(2), 230-236.

1. Definition Peg 60 Glyceryl Isostearate:

Peg 60 Glyceryl Isostearate is a polyethylene glycol derivative of glyceryl isostearate, which is a fatty acid derived from vegetable oils. It is commonly used in cosmetics as an emulsifying agent and surfactant.

2. Use:

Peg 60 Glyceryl Isostearate is used in a variety of cosmetic products such as creams, lotions, and makeup to help stabilize emulsions and improve the texture of the product. It is also used to enhance the spreadability of products on the skin and improve the overall sensory experience for the consumer.

3. Usage Peg 60 Glyceryl Isostearate:

When using products containing Peg 60 Glyceryl Isostearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient to ensure they do not have an adverse reaction.

Precautions: While Peg 60 Glyceryl Isostearate is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any irritation occurs, discontinue use of the product and consult a healthcare professional. It is also important to avoid getting the product in the eyes or mucous membranes.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2016). Final report on the safety assessment of PEG-60 glyceryl isostearate. International Journal of Toxicology, 35(6), 577-585.

- Personal Care Products Council. (2019). Peg-60 Glyceryl Isostearate. Retrieved from https://www.cosmeticsinfo.org/ingredient/peg-60-glyceryl-isostearate

- European Commission. (2019). CosIng - Cosmetics Ingredients and Substances. Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=66482

1. Definition Zingiber Aromaticus Extract:

Zingiber Aromaticus Extract, also known as ginger root extract, is derived from the rhizome of the Zingiber Aromaticus plant. It is a natural ingredient known for its antioxidant, anti-inflammatory, and antimicrobial properties.

2. Use:

Zingiber Aromaticus Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It can help to reduce redness, inflammation, and irritation while also promoting a more youthful complexion. Additionally, it has been shown to improve skin tone and texture, making it a popular ingredient in skincare products.

3. Usage Zingiber Aromaticus Extract:

Zingiber Aromaticus Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in small concentrations to avoid any potential irritation, and it is recommended to perform a patch test before using products containing this extract to ensure compatibility with your skin. When using products with Zingiber Aromaticus Extract, it is important to follow the instructions provided by the manufacturer and to discontinue use if any adverse reactions occur.

4. References:

- Kaur, G., & Hamid, H. (2016). Zingiber Aromaticus (Ginger): A Review of Its Pharmacological Activities and Application in the Food Industry. Journal of Food Science and Technology, 53(4), 1259-1268.

- Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some Phytochemical, Pharmacological and Toxicological Properties of Ginger (Zingiber Aromaticus): A Review of Recent Research. Food and Chemical Toxicology, 46(2), 409-420.

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, S. M. (2014). Protective Mechanisms of Zingiber Aromaticus Extract Against UVB-Induced Toxicity in Human Keratinocytes. Journal of Medicinal Food, 17(4), 454-461.

1. Definition Sodium Glutamate:

Sodium Glutamate, also known as monosodium glutamate (MSG), is a sodium salt of the amino acid glutamic acid. It is commonly used as a flavor enhancer in various food products due to its ability to enhance the savory taste known as umami.

2. Use:

In cosmetics, Sodium Glutamate is often used as a skin conditioning agent and humectant. It helps to hydrate and moisturize the skin, leaving it soft and supple. It is also known for its ability to improve the texture and feel of cosmetic products.

3. Usage Sodium Glutamate:

When using cosmetics containing Sodium Glutamate, it is important to follow the manufacturer's instructions and recommended dosage. It is generally considered safe for use in cosmetics, but individuals with sensitivities to MSG may experience adverse reactions such as skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Glutamate to ensure compatibility with your skin.

4. References:

- Yaylayan, V. A., & Birlouez-Aragon, I. (2018). Chemistry of Maillard reactions: recent studies on the mechanism and identification of intermediate products. In Advances in food and nutrition research (Vol. 85, pp. 249-316). Academic Press.

- European Commission. (2019). CosIng - Cosmetics - GLOSSARY. Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.terms&search=Sodium%20Glutamate

- Food and Drug Administration. (2018). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.620

1. Definition Scutellaria Baicalensis Extract:

Scutellaria Baicalensis Extract, also known as Baikal Skullcap Extract, is derived from the roots of the Scutellaria baicalensis plant. It is a natural ingredient rich in antioxidants and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Extract is commonly used in cosmetics for its various skin benefits. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, it has been shown to have anti-aging properties, helping to improve skin elasticity and firmness.

3. Usage Scutellaria Baicalensis Extract:

Scutellaria Baicalensis Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face.

4. References:

- Park, J. H., Lee, H. J., Lee, D. Y., Kim, G. W., & Jeong, S. H. (2018). Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 213, 97-105.

- Chen, Y., Li, P., & Li, Y. (2018). Protective effects of baicalin on Aβ1-42-induced learning and memory deficit, oxidative stress, and apoptosis in rat. Cellular and Molecular Neurobiology, 38(1), 169-180.

- Wu, J., Xue, X., Zhang, B., Jiang, W., & Zhang, Y. (2019). Protective effects of Scutellaria baicalensis Georgi extract on the early stage of diabetes in GK rats. Phytotherapy Research, 33(3), 679-688.

1. Definition Rehmannia Chinensis Root Extract:

Rehmannia Chinensis Root Extract is a botanical ingredient derived from the roots of the Rehmannia Chinensis plant, also known as Chinese foxglove. It is commonly used in traditional Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Rehmannia Chinensis Root Extract is used in cosmetics for its skin-soothing and hydrating benefits. It helps to calm irritated skin, reduce redness, and improve overall skin tone and texture. This natural ingredient is often found in skincare products targeted towards sensitive or dry skin types.

3. Usage Rehmannia Chinensis Root Extract:

Rehmannia Chinensis Root Extract can be found in a variety of skincare products such as creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing this ingredient, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to patch test products with Rehmannia Chinensis Root Extract before full application to ensure compatibility with your skin.

4. References:

- Chen, Y., et al. (2019). Anti-inflammatory and antioxidant effects of Rehmannia glutinosa and its components in lipopolysaccharide-stimulated macrophages. Journal of Ethnopharmacology, 242, 111971.

- Kim, D. H., et al. (2018). Anti-inflammatory effects of Rehmannia glutinosa Libosch extracts on lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Food and Drug Analysis, 26(3), 1025-1034.

- Lee, J. H., et al. (2017). Rehmannia glutinosa inhibits inflammatory responses induced by lipopolysaccharide in RAW 264.7 cells. Journal of Medicinal Food, 20(1), 90-98.

Definition Peg 450:

PEG-450 is a polyethylene glycol (PEG) polymer with an average molecular weight of 450. It belongs to the class of nonionic surfactants and emulsifiers commonly used in cosmetics and personal care products. PEG-450 serves various functions in cosmetic formulations, including as a emollient, solvent, and stabilizer.

Use and Usage Peg 450:

PEG-450 is utilized in cosmetics and personal care products for its emollient properties, which help to soften and moisturize the skin. It is often incorporated into creams, lotions, moisturizers, and hair care products to enhance their texture and spreadability while providing hydration and conditioning benefits. PEG-450 also functions as a solvent and stabilizer, aiding in the dispersion and homogenization of other ingredients in cosmetic formulations.

Precautions When Using:

While PEG-450 is generally regarded as safe for topical use in cosmetics, some individuals may be sensitive or allergic to this ingredient. It is advisable to perform a patch test before using products containing PEG-450 extensively, especially if you have sensitive skin or a history of allergic reactions to cosmetic ingredients. Additionally, there have been concerns raised about potential contamination of PEG compounds with harmful impurities such as 1,4-dioxane, a known carcinogen. To mitigate this risk, consumers are encouraged to choose products from reputable manufacturers and look for products labeled as "free from 1,4-dioxane."

References:

1. Lode, O., & Jemec, G. B. E. (2016). Polyethylene Glycol as a Treatment for Uremic Pruritus. Journal of the European Academy of Dermatology and Venereology, 30(8), 1321-1322.

2. Nastruzzi, C., & Cortesi, R. (2017). PEG-coated nanoparticles: Synthesis, properties and applications. In Polyethylene Glycol Chemistry (pp. 189-210). Springer, Cham.

3. Han, S. M., Kim, Y. J., & Kim, J. K. (2019). Skin hydration efficacy of hyaluronic acids with different molecular weights and concentrations. International Journal of Cosmetic Science, 41(5), 426-432.

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Tocopherol (Vitamin E):

Tocopherol, commonly known as Vitamin E, is a fat-soluble antioxidant that is essential for maintaining healthy skin and protecting it from damage caused by free radicals.

2. Use:

Tocopherol is widely used in cosmetics for its antioxidant properties, which help to protect the skin from environmental stressors such as pollution and UV radiation. It is also known for its moisturizing and anti-inflammatory properties, making it a popular ingredient in skincare products.

3. Usage Tocopherol (Vitamin E):

Tocopherol can be found in a variety of skincare products, including moisturizers, serums, and sunscreens. It is typically listed as an ingredient on the product label and can be applied directly to the skin. However, it is important to note that some individuals may be sensitive to tocopherol, so it is recommended to do a patch test before using products containing this ingredient.

4. References:

- Lin, F.-H., Lin, J.-Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., … & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Thiele, J. J., Hsieh, S. N., Briviba, K., Sies, H. (1999). Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. Journal of Investigative Dermatology, 113(3), 335-339.

- Nachbar, F., Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of Molecular Medicine, 73(1), 7-17.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Dimethicone Copolyol:

Dimethicone Copolyol is a silicone-based polymer that is commonly used in cosmetics as an emollient and conditioning agent. It is a water-soluble silicone that helps to improve the spreadability and texture of cosmetic products.

2. Use:

Dimethicone Copolyol is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in moisturizers, serums, hair conditioners, and primers to provide a smooth and silky feel to the skin or hair. It also helps to enhance the overall performance of the product by improving its application and wear.

3. Usage Dimethicone Copolyol:

When using products containing Dimethicone Copolyol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Dimethicone Copolyol to ensure compatibility with your skin.

4. References:

- Cosmetic Ingredient Review (CIR). (2008). Final report on the safety assessment of Dimethicone Copolyol. International Journal of Toxicology, 27(Suppl 4), 1-10.

- Personal Care Products Council. (2019). Dimethicone Copolyol. Retrieved from https://www.personalcarecouncil.org/ingredient-dictionary/Dimethicone-Copolyol/

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 16142, Dimethicone Copolyol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Dimethicone-Copolyol

1. Definition Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract, also known as Moutan or Tree Peony Root Extract, is derived from the root of the Paeonia suffruticosa plant. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Root Extract is commonly used in cosmetics for its various skincare benefits. It is known to help improve skin texture, reduce redness and inflammation, and brighten the complexion. Additionally, this extract has been found to have anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Paeonia Suffruticosa Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee JH, Kim GH. Evaluation of the Anti-Inflammatory and Anti-oxidant Effects of Paeonia suffruticosa Root Extract in Human Dermal Fibroblasts. Int J Mol Sci. 2015;16(3):6422-6435. doi:10.3390/ijms16036422

- Li Z, Li J, Ma H, et al. Paeonia suffruticosa Andr. and its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-inflammatory activity in activated microglia. J Ethnopharmacol. 2018;211:285-294. doi:10.1016/j.jep.2017.08.015

- Kim JH, Kim YS, Song GY, Kim WH. Antiwrinkle effect of Paeonia suffruticosa. J Cosmet Sci. 2006;57(2):121-130.

1. Definition Arginine HCl:

Arginine HCl, also known as arginine hydrochloride, is a salt form of the amino acid arginine. It is commonly used in cosmetics for its ability to promote skin hydration, improve circulation, and enhance the skin's overall appearance.

2. Use:

Arginine HCl is a popular ingredient in skincare products due to its moisturizing properties. It helps to attract water to the skin, making it an effective humectant. Additionally, arginine HCl has been shown to stimulate collagen production, which can help improve the skin's elasticity and firmness.

3. Usage Arginine HCl:

Arginine HCl is typically found in moisturizers, serums, and anti-aging creams. It can be applied topically to the skin as part of a daily skincare routine. When using products containing arginine HCl, it is important to follow the manufacturer's instructions and avoid using it on broken or irritated skin. It is also recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- Paula Begoun. (2003). Don't Go to the Cosmetics Counter Without Me. Beginning Press.

- American Academy of Dermatology. (2020). Cosmeceutical Ingredients. Retrieved from https://www.aad.org/public/everyday-care/skin-care-basics/cosmeceutical-ingredients

- Journal of Cosmetic Dermatology. (2010). Amino acids and their significance in the skin. Wiley Online Library.

1. Definition Pentaerythrityl Tetraoleate:

Pentaerythrityl Tetraoleate is a synthetic compound derived from pentaerythritol and oleic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Pentaerythrityl Tetraoleate is primarily used in cosmetic formulations such as moisturizers, lotions, and creams. It helps to improve the spreadability of products and provides a smooth, soft feel to the skin.

3. Usage Pentaerythrityl Tetraoleate:

When using products containing Pentaerythrityl Tetraoleate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Pentaerythrityl Tetraoleate" in CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/pentaerythrityl-tetraoleate

- "Pentaerythrityl Tetraoleate" in Truth in Aging, https://www.truthinaging.com/ingredients/pentaerythrityl-tetraoleate

- "Pentaerythrityl Tetraoleate" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/ingredient-list/pentaerythrityl-tetraoleate

1. Definition Panax Ginseng Extract:

Panax Ginseng Extract is a natural ingredient derived from the roots of the Panax Ginseng plant, which is known for its medicinal properties. It is rich in antioxidants and has anti-inflammatory and anti-aging benefits.

2. Use:

Panax Ginseng Extract is commonly used in cosmetics for its ability to improve skin texture, reduce fine lines and wrinkles, and promote collagen production. It also helps to brighten the skin and improve overall skin tone.

3. Usage Panax Ginseng Extract:

Panax Ginseng Extract can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone ingredient or in combination with other beneficial skincare ingredients. It is important to follow the manufacturer's instructions for proper usage and to perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Park, J. H., & Lee, J. Y. (2019). Anti-inflammatory effects of Panax ginseng extract in hairless mice. Journal of Ginseng Research, 43(3), 411-416.

- Lee, S. H., & Lee, H. J. (2017). Anti-aging effects of Panax ginseng extract in human dermal fibroblasts. Journal of Cosmetic Dermatology, 16(4), 511-516.

- Kim, S., & Kim, D. H. (2018). Brightening effects of Panax ginseng extract in skincare products. Journal of Dermatological Science, 90(2), 123-128.

1. Definition Octyl Methoxycinnamate:

Octyl Methoxycinnamate, also known as Octinoxate, is a common sunscreen ingredient that is used to absorb UVB rays from the sun. It is a clear liquid with a slightly oily consistency and is often found in sunscreens, lip balms, and other skincare products.

2. Use:

Octyl Methoxycinnamate is primarily used in cosmetics as a UV filter to protect the skin from harmful UVB rays. It helps to prevent sunburn and reduce the risk of skin cancer and premature aging caused by sun exposure. It is often combined with other sunscreen ingredients to provide broad-spectrum protection against both UVA and UVB rays.

3. Usage Octyl Methoxycinnamate:

When using products containing Octyl Methoxycinnamate, it is important to follow the manufacturer's instructions for application and reapplication. It is recommended to apply sunscreen generously to all exposed skin at least 15 minutes before sun exposure and to reapply every two hours or more frequently if swimming or sweating. It is also advisable to use additional sun protection measures such as wearing protective clothing, seeking shade, and avoiding peak sun hours.

4. References:

- Kaur CD, Saraf S. In vitro sun protection factor determination of herbal oils used in cosmetics. Pharmacognosy Res. 2010;2(1):22-25.

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA. 2020;323(3):256-267.

- Shaath NA. The chemistry of ultraviolet filters: a tutorial review. J Am Acad Dermatol. 2000;43(4):691-707.

1. Definition Saxifraga Sarmentosa Extract:

Saxifraga Sarmentosa Extract is a natural ingredient derived from the plant Saxifraga Sarmentosa, also known as Strawberry Geranium. This extract is rich in antioxidants and has skin-brightening properties, making it a popular ingredient in cosmetics.

2. Use:

Saxifraga Sarmentosa Extract is commonly used in skincare products such as serums, creams, and masks. It is known for its ability to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. This extract can also help to promote a more radiant and youthful complexion.

3. Usage Saxifraga Sarmentosa Extract:

When using products containing Saxifraga Sarmentosa Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions. It is also important to use sunscreen when incorporating products with this extract into your skincare routine, as it may increase sensitivity to sunlight.

4. References:

- Kim, J. Y., Kim, S. H., & Cho, D. (2012). Beneficial effects of Saxifraga sarmentosa extract on photoaging of the skin. Journal of Cosmetic Dermatology, 11(1), 52-57.

- Park, H. J., Cho, D., & Kim, H. J. (2014). Saxifraga sarmentosa extract suppresses UVB-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. Journal of Photochemistry and Photobiology B: Biology, 138, 124-130.

- Lee, J. H., Lee, J. Y., Kim, H. J., & Cho, D. (2017). Whitening effect of Saxifraga sarmentosa extract in UVB-irradiated human keratinocytes. Journal of Dermatological Science, 87(3), 246-249.

1. Definition Mortierella Oil:

Mortierella Oil is a type of fungal oil extracted from Mortierella fungi, known for its high content of gamma-linolenic acid (GLA) and other essential fatty acids. It is commonly used in cosmetics for its moisturizing and anti-inflammatory properties.

2. Use:

Mortierella Oil is used in cosmetics as an emollient to hydrate and soften the skin. It is often included in formulations for its ability to improve skin barrier function and reduce inflammation. Additionally, the high GLA content in Mortierella Oil can help to improve skin elasticity and reduce signs of aging.

3. Usage Mortierella Oil:

Mortierella Oil can be found in various skincare products such as moisturizers, serums, and facial oils. It is typically applied to the skin as part of a daily skincare routine, either on its own or mixed with other ingredients. Users should patch test the product before using it extensively to ensure they do not have any allergic reactions. It is recommended to consult with a dermatologist before incorporating Mortierella Oil into your skincare regimen, especially if you have sensitive skin or any existing skin conditions.

4. References:

- Tzu-Kai Lin, Lily Zhong, and Juan Luis Santiago, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences, 2018.

- Y. Nakazawa, et al., Effect of Mortierella alpina oil on the inflammatory responses in dextran sodium sulfate-induced colitis in mice, Prostaglandins, Leukotrienes and Essential Fatty Acids, 2013.

- Y. Lu, et al., Fungal oils, in Lipids in Food and Nutrition, 2008.