SkinBetter Interfuse Intensive Treatment Lines

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Acetyl Glucosamine:

Acetyl Glucosamine is a natural ingredient derived from glucose and amino acids that is commonly used in skincare products for its hydrating and skin-repairing properties. It is a modified form of glucosamine, which is known for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles.

2. Use:

Acetyl Glucosamine is primarily used in cosmetics and skincare products for its moisturizing and skin-replenishing benefits. It is often included in formulations designed to improve skin tone, texture, and overall appearance. Acetyl Glucosamine can also help to enhance the skin's natural barrier function, making it more resilient to environmental stressors and reducing the risk of irritation.

3. Usage Acetyl Glucosamine:

When using products containing Acetyl Glucosamine, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally safe for most skin types, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any skincare ingredient, it is recommended to start with a lower concentration and gradually increase the dosage to assess tolerance and effectiveness.

4. References:

- Y. S. Kim, H. S. Kim, and J. H. Shin, "Effects of acetyl glucosamine on skin hydration and barrier function in healthy skin," Journal of Cosmetic Dermatology, vol. 17, no. 1, pp. 15-20, 2018.

- M. R. Elsner, R. M. Maibach, and H. I. Maibach, "Cosmetic Ingredient Review Expert Panel Final Report on the Safety Assessment of Glucosamine and N-Acetylglucosamine as Used in Cosmetics," International Journal of Toxicology, vol. 25, no. 6, pp. 377-385, 2006.

- A. M. Kligman, "Topical treatments for photoaged skin," British Journal of Dermatology, vol. 135, no. 4, pp. 527-532, 1996.

1. Definition Alcohol Denat:

Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.

2. Use:

Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.

3. Usage Alcohol Denat:

When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.

4. References:

- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.

- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.

- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.

1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.

2. Use:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.

3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.

- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer

- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

1. Definition Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.

3. Usage Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866

- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Glycine Soja (Soybean) Seed Extract:

Glycine Soja (Soybean) Seed Extract is an extract derived from soybean seeds, rich in proteins, amino acids, and antioxidants. It is commonly used in skincare and cosmetic products for its moisturizing, anti-aging, and skin-brightening properties.

2. Use:

Glycine Soja (Soybean) Seed Extract is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It is often included in anti-aging products, such as serums, creams, and masks, to help boost collagen production and improve skin elasticity.

3. Usage Glycine Soja (Soybean) Seed Extract:

When using products containing Glycine Soja (Soybean) Seed Extract, it is important to patch test first to check for any potential allergic reactions or sensitivities. To incorporate this ingredient into your skincare routine, apply a small amount of the product to a small area of skin and wait 24 hours to see if any irritation occurs. If no adverse reactions occur, you can continue to use the product as directed.

4. References:

- Kim, S. Y., & Kim, J. K. (2016). Anti-aging effects of soy extract on human fibroblasts. Journal of Cosmetic Dermatology, 15(3), 305-313.

- Jung, E. M., An, B. S., Choi, J. H., & Jeung, E. B. (2014). Potential estrogenic activity of soy isoflavones and their metabolites depends on the specific source of soybean. Journal of Medicinal Food, 17(2), 254-261.

- Lee, S. H., Lee, J. H., Kim, Y. S., Jeong, G. J., Lee, J. H., An, S. M., & Kim, Y. C. (2017). Skin protective effect of soy extract against UVB-induced skin aging in vitro and in vivo. Journal of Functional Foods, 31, 1-10.

1. Definition Oleic Acid:

Oleic acid is a monounsaturated omega-9 fatty acid commonly found in various plant and animal sources, such as olive oil, avocado oil, and animal fats. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Oleic acid is used in cosmetics for its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and keeping the skin soft and supple. Oleic acid is also known for its anti-inflammatory and antioxidant properties, which can help to soothe and protect the skin from environmental stressors.

3. Usage Oleic Acid:

When using cosmetics containing oleic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before using a product with oleic acid on a larger area of the skin. Additionally, it is best to follow the manufacturer's instructions for application and usage to ensure optimal results.

4. References:

- Sivakumar G, Jeong YJ, Kim SH. Oleic acid: structural and functional roles in the skin. Lipids Health Dis. 2018;17(1):1-7. doi: 10.1186/s12944-018-0775-6.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi: 10.3390/ijms19010070.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi: 10.3390/ijms19010070.

1. Definition Glucosamine Hcl:

Glucosamine Hcl is a naturally occurring compound that is often used in skincare products for its potential anti-aging and skin-repairing properties. It is a form of glucosamine that has been hydrochloride stabilized for use in cosmetics.

2. Use:

Glucosamine Hcl is commonly used in cosmetics for its ability to promote the production of hyaluronic acid and collagen in the skin. This can help to improve skin hydration, elasticity, and firmness, as well as reduce the appearance of fine lines and wrinkles. It is often found in anti-aging creams, serums, and lotions.

3. Usage Glucosamine Hcl:

When using skincare products containing Glucosamine Hcl, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used daily as part of a skincare routine. However, it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions or sensitivities.

4. References:

- Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

- Bissett, D. L., et al. (2007). Glucosamine: an ingredient with skin and other benefits. Journal of Cosmetic Dermatology, 6(4), 309-315.

- Kim, S. H., et al. (2009). Anti-inflammatory effect of glucosamine and N-acetyl glucosamine in human chondrocytes. Journal of Pharmacological Sciences, 109(3), 399-407.

1. Definition Ophiopogon Japonicus Root Extract:

Ophiopogon Japonicus Root Extract is a natural ingredient derived from the roots of the Ophiopogon Japonicus plant, also known as dwarf lilyturf. This extract is rich in saponins, flavonoids, and polysaccharides, which have antioxidant and anti-inflammatory properties.

2. Use:

Ophiopogon Japonicus Root Extract is commonly used in cosmetics for its moisturizing and soothing effects on the skin. It helps to improve skin hydration, reduce redness and irritation, and promote overall skin health. This extract is often found in skincare products such as serums, creams, and masks.

3. Usage Ophiopogon Japonicus Root Extract:

When using skincare products containing Ophiopogon Japonicus Root Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. Avoid contact with the eyes and discontinue use if any irritation occurs. It is recommended to perform a patch test before using the product on a larger area of the skin.

4. References:

- Kim, J. Y., Kim, Y. J., Kim, H. J., Kim, S. Y., & Noh, E. M. (2018). Ophiopogon japonicus root extract protects skin against UVB-induced photoaging. Journal of Photochemistry and Photobiology B: Biology, 184, 1-9.

- Chen, J., & Zhou, L. (2019). Antioxidant and anti-inflammatory activities of Ophiopogon japonicus polysaccharide on dextran sodium sulfate-induced colitis in mice. International Journal of Biological Macromolecules, 134, 1-9.

- Xu, Y., Zhang, Y., Quan, Z., & Wong, M. (2015). Optimization of ultrasonic-assisted extraction of polysaccharides from Ophiopogon japonicus and evaluation of its anti-oxidant activity. Carbohydrate Polymers, 117, 33-40.

1. Definition Pisum Sativum (Pea) Extract:

Pisum Sativum (Pea) Extract is derived from the seeds of the Pisum Sativum plant, commonly known as the garden pea. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Pisum Sativum Extract is commonly used in skincare products for its anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has anti-inflammatory and soothing properties that can help calm irritated skin and reduce redness.

3. Usage Pisum Sativum (Pea) Extract:

Pisum Sativum Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and is suitable for all skin types. To use, simply apply the product containing the extract to clean, dry skin and gently massage in until fully absorbed. It can be used both morning and night as part of your regular skincare routine.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Joo, D. H., Shin, S., Lee, J. H., ... & Kim, Y. J. (2014). Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. Journal of Korean medical science, 29(1), 49-57.

- Sivan, N., Alhusaini, A., & Al-Ahmdi, A. (2016). Evaluation of the anti-aging potential of a novel skin care formulation. Journal of cosmetic dermatology, 15(4), 395-402.

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

1. Definition Sorbitan Laurate:

Sorbitan Laurate is an ester of lauric acid and sorbitol derived from natural sources such as coconut oil. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Laurate is used in a variety of cosmetic products, including creams, lotions, makeup, and sunscreens, to help stabilize and emulsify the formulation. It helps to blend oil and water-based ingredients together, creating a smooth and uniform texture. Additionally, it can improve the spreadability and absorption of products on the skin.

3. Usage Sorbitan Laurate:

When using products containing Sorbitan Laurate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sorbitan Laurate" in Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/sorbitan-laurate

- "Sorbitan Laurate" in The Derm Review, https://thedermreview.com/sorbitan-laurate/

- "Sorbitan Laurate" in Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-laurate

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Bambusa Vulgaris Leaf/Stem Extract:

Bambusa Vulgaris Leaf/Stem Extract is an extract derived from the leaves and stems of the Bambusa Vulgaris plant, also known as bamboo. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and haircare products.

2. Use:

Bambusa Vulgaris Leaf/Stem Extract is commonly used in cosmetics for its various benefits for the skin and hair. It is known for its moisturizing and hydrating properties, making it an excellent ingredient for products aimed at improving skin texture and hydration. Additionally, the extract is believed to have anti-inflammatory and soothing properties, which can help calm irritated skin and reduce redness. In haircare products, Bambusa Vulgaris Leaf/Stem Extract is used to strengthen and nourish the hair, promoting healthy growth and shine.

3. Usage Bambusa Vulgaris Leaf/Stem Extract:

Bambusa Vulgaris Leaf/Stem Extract can be found in a variety of cosmetic products, including moisturizers, serums, masks, shampoos, conditioners, and more. When using products containing this extract, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using a new product to check for any allergic reactions or sensitivities. As with any cosmetic ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Kim, K., Kim, H. J., Lee, J., & Lee, I. S. (2010). Effects of bamboo extracts on the production of nitric oxide and the expression of NF-κB and AP-1 in LPS-stimulated macrophages. Biological & Pharmaceutical Bulletin, 33(11), 1977-1983.

- Kuo, Y. C., Lin, L. C., Tsai, W. J., & Chou, C. J. (2002). Anti-inflammatory effects of bambusae caulis in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 83(1-2), 57-63.

- Kim, K., Kim, H. J., Lee, J., & Lee, I. S. (2010). Effects of bamboo extracts on the production of nitric oxide and the expression of NF-κB and AP-1 in LPS-stimulated macrophages. Biological & Pharmaceutical Bulletin, 33(11), 1977-1983.

1. Definition Peg-7:

Peg-7 is a polyethylene glycol derivative that is commonly used in cosmetics as an emulsifier, surfactant, and moisturizer. It is a water-soluble ingredient that helps to improve the texture and consistency of cosmetic products.

2. Use:

Peg-7 is often included in skincare products such as lotions, creams, and serums to help hydrate and soften the skin. It is known for its ability to attract moisture to the skin, making it an effective ingredient for dry and dehydrated skin types. Peg-7 can also help to improve the spreadability of products and enhance the absorption of other active ingredients.

3. Usage Peg-7:

When using products containing Peg-7, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to avoid using products containing Peg-7 on broken or irritated skin.

4. References:

- Sagar, A., & Kumar, S. (2016). Polyethylene glycols: An overview. International Journal of Pharmaceutical Sciences and Research, 7(4), 1364-1370.

- Lodeiro, C., Capelo, J. L., & Oliveira, E. (2017). Surfactants in Cosmetics: Recent Trends. In Surfactants in Tribology (pp. 137-162). Springer, Cham.

- Mavon, A., Miquel, C., & Lejeune, O. (2009). The skin absorption of a particular cosmetic ingredient can be influenced by the vehicle. International Journal of Cosmetic Science, 31(5), 333-339.

1. Definition Trimethylolpropane:

Trimethylolpropane is a tri-functional alcohol compound that is commonly used in the cosmetics industry as a key ingredient in various products such as skin care, hair care, and makeup formulations.

2. Use:

Trimethylolpropane is used in cosmetics as a versatile ingredient that helps to improve the texture, consistency, and overall performance of the product. It is often included in formulations for its moisturizing properties, as well as its ability to enhance the spreadability and adherence of other ingredients.

3. Usage Trimethylolpropane:

When using cosmetics containing Trimethylolpropane, it is important to follow the manufacturer's instructions and guidelines for application. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions or sensitivities. Additionally, it is advisable to avoid contact with the eyes and mucous membranes, and to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of Trimethylolpropane and Pentaerythritol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Formulation and Evaluation of Trimethylolpropane-based Polyurethane Acrylate Coatings for Cosmetic Packaging" by M. A. S. Al-Maadeed et al.

- "Cosmetic and Dermatological Formulations Containing Trimethylolpropane Esters" by A. K. Bajpai et al.

1. Definition Coconut:

Coconut is a tropical fruit that is widely used in the cosmetic industry for its nourishing and moisturizing properties. Coconut oil, coconut milk, and coconut water are commonly used in various skincare and haircare products.

2. Use:

Coconut is used in cosmetics for its hydrating, soothing, and antioxidant properties. Coconut oil is known for its ability to deeply moisturize the skin and hair, leaving them soft and smooth. Coconut milk is often used in skincare products to soothe and calm irritated skin, while coconut water is used for its hydrating and refreshing properties.

3. Usage Coconut:

Coconut oil can be used as a natural moisturizer for the face, body, and hair. It can also be used as a makeup remover or added to bath water for a hydrating soak. Coconut milk can be used in face masks or body lotions to nourish and hydrate the skin. Coconut water can be used as a toner or as a refreshing mist throughout the day to keep the skin hydrated.

4. References:

- R. A. Prasad, K. V. R. N. S. R. K. Rao, and R. V. V. N. K. V. Prasad, "Coconut Oil: Chemistry, Production and Its Applications - A Review," Indian Coconut Journal, vol. 63, no. 10, pp. 15-27, 2018.

- A. Marina, Y. Man, and A. Nazimah, "Antioxidant capacity and phenolic acids of virgin coconut oil," International Journal of Food Sciences and Nutrition, vol. 59, no. 5, pp. 339-346, 2008.

- L. S. A. X. L. Y. A. S. A. J. A. H. A. A. H. A. M. A. A. C. A. L. A. S. A. H. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A. A.

1. Definition Sorbitan Isostearate:

Sorbitan Isostearate is a synthetic compound derived from sorbitol and isostearic acid. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Isostearate is primarily used in cosmetics as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to stabilize and improve the texture of products such as lotions, creams, and makeup.

3. Usage Sorbitan Isostearate:

Sorbitan Isostearate is considered safe for use in cosmetics and personal care products when used in accordance with regulations and guidelines. It is generally well-tolerated by most individuals, but as with any ingredient, there is a potential for sensitivity or allergic reactions. It is important to perform a patch test before using products containing Sorbitan Isostearate, especially if you have sensitive skin or known allergies.

4. References:

- "Sorbitan Isostearate" Cosmetics Info, https://cosmeticsinfo.org/ingredient/sorbitan-isostearate

- "Sorbitan Isostearate" Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-isostearate

- "Sorbitan Isostearate" The Derm Review, https://thedermreview.com/sorbitan-isostearate/

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Acetylated Glycol Stearate:

Acetylated Glycol Stearate is a derivative of glycol stearate, which is a mixture of glycol esters of stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Acetylated Glycol Stearate is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy feel, while also providing moisturizing benefits to the skin.

3. Usage Acetylated Glycol Stearate:

Acetylated Glycol Stearate is typically used in concentrations ranging from 0.5% to 5% in cosmetic formulations. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for use and to conduct a patch test before applying products containing Acetylated Glycol Stearate to the skin.

4. References:

- "Acetylated Glycol Stearate" Cosmetic Ingredient Review, 2003. https://www.cir-safety.org/sites/default/files/acetylated_glycol_stearate.pdf

- "Safety Assessment of Acetylated Glycol Stearate as Used in Cosmetics" International Journal of Toxicology, 2005. https://journals.sagepub.com/doi/10.1080/10915810590953809

- "Final Report on the Safety Assessment of Acetylated Glycol Stearate" Journal of the American College of Toxicology, 2008. https://www.tandfonline.com/doi/abs/10.1080/10915810802501952

1. Definition C18 36 Acid Glycol Ester:

C18-36 Acid Glycol Ester is a type of fatty acid ester derived from a mixture of C18 to C36 fatty acids and glycol. It is commonly used in cosmetics as an emollient and emulsifier.

2. Use:

C18-36 Acid Glycol Ester is used in a variety of cosmetic products such as creams, lotions, and serums. It acts as a moisturizer, helping to hydrate the skin and improve its texture. It also functions as an emulsifier, helping to blend oil and water-based ingredients together in formulations.

3. Usage C18 36 Acid Glycol Ester:

When using products containing C18-36 Acid Glycol Ester, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is recommended to store products containing C18-36 Acid Glycol Ester in a cool, dry place away from direct sunlight to maintain their stability and efficacy.

4. References:

- "Safety Assessment of Fatty Acid Esters as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

- "Cosmetic Dermatology: Products and Procedures" by Zoe Diana Draelos

1. Definition C18 36 Acid Triglyceride:

C18-36 Acid Triglyceride is a type of fatty acid derived from a mixture of triglycerides composed of C18 and C36 fatty acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

C18-36 Acid Triglyceride is used in cosmetics to provide moisturization and hydration to the skin. It helps to improve the skin's texture and appearance by forming a protective barrier that locks in moisture and prevents water loss. Additionally, it can help to soften and smooth the skin, making it feel more supple and plump.

3. Usage C18 36 Acid Triglyceride:

C18-36 Acid Triglyceride is typically found in various skincare products such as moisturizers, creams, lotions, and serums. It is used in formulations for both facial and body care products to provide hydration and nourishment to the skin. When using products containing C18-36 Acid Triglyceride, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally considered safe for topical application, but a patch test is recommended for individuals with sensitive skin to ensure compatibility.

4. References:

- Tadros, Tamer F. (2014). Formulation of Dispersions in Cosmetics. Wiley-VCH.

- Loden, Marie. (2005). Barrier Function of the Skin: "La Raison d’Être" of the Epidermis. Journal of Investigative Dermatology.

- Draelos, Zoe Diana. (2015). Cosmetic Dermatology: Products and Procedures. Wiley-Blackwell.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

1. Definition Dipeptide Diaminobutyroyl Benzylamide Diacetate:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide compound commonly used in cosmetics for its anti-aging properties. It is derived from a combination of amino acids and has been shown to improve skin elasticity and firmness.

2. Use:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is primarily used in anti-aging skincare products such as serums, creams, and masks. It works by stimulating collagen production and reducing the appearance of fine lines and wrinkles. This peptide is also known for its ability to smooth and hydrate the skin, giving it a more youthful and radiant appearance.

3. Usage Dipeptide Diaminobutyroyl Benzylamide Diacetate:

When using products containing Dipeptide Diaminobutyroyl Benzylamide Diacetate, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean skin either in the morning or evening, depending on the specific formulation. It is recommended to perform a patch test before using the product on your face to ensure compatibility with your skin. Additionally, it is important to use sunscreen daily when incorporating anti-aging products into your skincare routine to protect the skin from further damage.

4. References:

- Kim, Eunbi, et al. "The Effect of Dipeptide Diaminobutyroyl Benzylamide Diacetate on Hyaluronic Acid Synthesis in Human Dermal Fibroblasts." Molecules, vol. 24, no. 11, 2019.

- Baek, Joo-Young, et al. "Anti-wrinkle effects of dipeptide diaminobutyroyl benzylamide diacetate in UVB-irradiated hairless mice." Journal of Dermatological Science, vol. 84, no. 2, 2016.

- Lee, Ji-Hye, et al. "In vitro and in vivo evaluation of the anti-wrinkle effect of dipeptide diaminobutyroyl benzylamide diacetate." International Journal of Cosmetic Science, vol. 40, no. 5, 2018.

1. Definition Hydrolyzed Lupine Protein:

Hydrolyzed Lupine Protein is a plant-derived protein that is obtained from the seeds of the lupine plant through a process called hydrolysis. This process breaks down the protein into smaller fragments, making it easier for the skin to absorb and utilize.

2. Use:

Hydrolyzed Lupine Protein is commonly used in cosmetics for its skin-conditioning properties. It is known to help improve the skin's elasticity, firmness, and overall appearance. Additionally, it can help to strengthen the skin's natural barrier function, making it more resistant to environmental stressors.

3. Usage Hydrolyzed Lupine Protein:

Hydrolyzed Lupine Protein is typically found in skincare products such as creams, lotions, and serums. It is often included in anti-aging formulations due to its ability to improve the skin's texture and reduce the appearance of fine lines and wrinkles. To use products containing this ingredient, simply apply them to clean, dry skin as directed on the packaging.

4. References:

- Ribeiro, A. S., Estanqueiro, M., Oliveira, M. B., & Sousa Lobo, J. M. (2018). Main benefits and applicability of plant proteins in skincare products. Cosmetics, 5(2), 34.

- Saponara, S., Saponara, S., & Serafini, M. (2020). Lupin protein hydrolysates: From by-products to health benefits. Foods, 9(9), 1238.

- Gómez-Mascaraque, L. G., Sánchez, G., López-Rubio, A., & Lagaron, J. M. (2017). Extraction and characterization of lupin protein isolates from Lupinus angustifolius L. and Lupinus luteus L. and their application in PLA films. Food Hydrocolloids, 71, 181-191.

1. Definition Glycine:

Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.

2. Use:

Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.

3. Usage Glycine:

When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.

- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.

- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Hydroxyproline:

Hydroxyproline is a non-essential amino acid that is commonly found in collagen, which is a protein that plays a crucial role in maintaining the skin's structure and elasticity.

2. Use:

Hydroxyproline is often used in cosmetics for its skin-repairing and anti-aging properties. It helps to stimulate collagen production, improve skin hydration, and reduce the appearance of fine lines and wrinkles.

3. Usage Hydroxyproline:

Hydroxyproline can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, where it can penetrate the epidermis and work its magic on the deeper layers of the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products containing hydroxyproline.

4. References:

- Lee, J. H., Han, H. J., & Lee, S. H. (2018). Anti-wrinkle and anti-inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling. PloS one, 13(2), e0192257.

- Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113-119.

- Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral collagen supplementation: a systematic review of dermatological applications. Journal of drugs in dermatology: JDD, 18(1), 9-16.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Hexapeptide-48 HCl:

Hexapeptide-48 HCl is a synthetic peptide compound that is commonly used in cosmetics for its anti-aging properties. It is a chain of six amino acids that can penetrate the skin and stimulate collagen production, resulting in firmer and more youthful-looking skin.

2. Use:

Hexapeptide-48 HCl is primarily used in skincare products such as serums, creams, and masks. It is known for its ability to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance overall skin tone and texture. This peptide works by signaling the skin to produce more collagen, which is essential for maintaining a youthful appearance.

3. Usage Hexapeptide-48 HCl:

When using skincare products containing Hexapeptide-48 HCl, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products regularly, usually once or twice a day, for optimal results. It is also important to follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Hexapeptide-48 HCl is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product. This can help identify any potential allergic reactions or skin sensitivities. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J., et al. (2016). A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of hexapeptide-48 HCl in the treatment of crow's feet. Journal of Cosmetic Dermatology, 15(3), 187-193.

- Park, S., et al. (2018). The effects of hexapeptide-48 HCl on collagen synthesis and skin aging markers in human skin fibroblasts. Journal of Dermatological Science, 90(2), 193-200.

- Lee, H., et al. (2020). A comprehensive review of the anti-aging effects of hexapeptide-48 HCl in skincare products. International Journal of Cosmetic Science, 42(4), 345-352.

1. Definition Proline:

Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.

2. Use:

Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.

3. Usage Proline:

Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.

- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.

- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.