Name: SkinCeuticals Blemish Age Defense Salicylic Acid Acne Treatment
Brand: SkinCeuticals
Rating: 5 (6 reviews)

Water

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

Sodium Hyaluronate

Other Names: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Polyquaternium 10

Function: Antistatic Agent, Film Forming, Hair Fixing

1. Definition Polyquaternium 10:

Polyquaternium 10 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent. It is a water-soluble polymer that helps improve the texture and feel of the product, as well as providing conditioning benefits to the hair and skin.

2. Use:

Polyquaternium 10 is used in a variety of cosmetic products, including shampoos, conditioners, hair styling products, and body lotions. It helps to improve the overall performance of these products by providing conditioning benefits, reducing static electricity, and enhancing the texture and feel of the hair and skin.

3. Usage Polyquaternium 10:

When using products containing Polyquaternium 10, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, damp hair or skin and left on for a specified amount of time before rinsing off. It is important to avoid getting the product in the eyes, and if irritation occurs, discontinue use immediately.

4. References:

- "Polyquaternium-10." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/polyquaternium-10

- "Polyquaternium-10." The Derm Review, https://thedermreview.com/polyquaternium-10/

- "Polyquaternium-10." Truth In Aging, https://www.truthinaging.com/ingredients/polyquaternium-10

Salicylic Acid

Other Names: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

Glycolic Acid

Other Names: Hydroxyacetic acid

Function: pH adjusting agent, pH adjusting agent, Exfoliant

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

Methylpropanediol

Function: Solvent

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

Diisopropyl Adipate

Function: Solvent, Masking, Fragrance, Skin Conditioning, Emollient, Plasticizer

1. Definition Diisopropyl Adipate:

Diisopropyl Adipate is a clear, colorless liquid ester that is commonly used in cosmetics as a skin conditioning agent and emollient. It is derived from adipic acid and isopropyl alcohol.

2. Use:

Diisopropyl Adipate is used in a variety of cosmetic formulations such as lotions, creams, and sunscreens. It helps to improve the texture and feel of the product by providing a smooth and silky finish. Additionally, it can enhance the spreadability of the product on the skin, making it easier to apply.

3. Usage Diisopropyl Adipate:

When using Diisopropyl Adipate in cosmetics, it is important to follow the recommended guidelines and use it in the appropriate concentration as specified by the manufacturer. It is generally considered safe for use in cosmetics, but as with any ingredient, it is recommended to perform a patch test before widespread use to check for any potential allergic reactions. It is also important to store products containing Diisopropyl Adipate in a cool, dry place away from direct sunlight to maintain its stability and efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Final report on the safety assessment of diisopropyl adipate. International Journal of Toxicology, 33(3), 36S-44S.

- Personal Care Products Council. (2008). Diisopropyl Adipate. Retrieved from https://www.cosmeticsinfo.org/ingredient/diisopropyl-adipate

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.3400

Capryloyl Salicylic Acid

Function: Skin Conditioning

1. Definition Capryloyl Salicylic Acid:

Capryloyl Salicylic Acid is a derivative of salicylic acid that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It is a lipophilic beta-hydroxy acid that is known for its ability to penetrate the skin and unclog pores.

2. Use:

Capryloyl Salicylic Acid is often used in cosmetics and skincare products as an exfoliant to help remove dead skin cells, unclog pores, and improve overall skin texture. It is also known for its anti-inflammatory properties, making it a popular ingredient in products designed for acne-prone or sensitive skin.

3. Usage Capryloyl Salicylic Acid:

When using products containing Capryloyl Salicylic Acid, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of the ingredient to minimize the risk of irritation or sensitivity. It is also important to use sunscreen when using products with Capryloyl Salicylic Acid, as it can increase skin sensitivity to the sun.

4. References:

- Kwon HH, Lee JB, Yoon JY, et al. Clinical and histological effect of a low molecular weight beta-hydroxy acid skin care regimen in facial photoaging. J Cosmet Dermatol. 2009;8(4):228-233.

- Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348.

- Draelos ZD. Cosmeceuticals for the aging skin. J Drugs Dermatol. 2007;6(9):879-882.

Hydroxyethylpiperazine Ethane Sulfonic Acid

Other Names: HEPES

Function: pH adjusting agent

1. Definition Hydroxyethylpiperazine Ethane Sulfonic Acid:

Hydroxyethylpiperazine Ethane Sulfonic Acid, also known as HEPES, is a synthetic organic compound commonly used in cosmetics as a buffering agent and pH adjuster. It is a zwitterionic buffer with a pKa of 7.55, making it ideal for maintaining the pH of cosmetic formulations.

2. Use:

HEPES is primarily used in cosmetics to stabilize the pH of products, ensuring that they remain within the desired range for optimal efficacy and safety. It is often found in skincare products, hair care products, and makeup formulations to maintain the stability and effectiveness of active ingredients.

3. Usage Hydroxyethylpiperazine Ethane Sulfonic Acid:

When using products containing HEPES, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Draelos, Z. Hydroxyethylpiperazine Ethane Sulfonic Acid. Cosmetics and Dermatological Problems and Solutions. 2017.

- Lupo, M. Hydroxyethylpiperazine Ethane Sulfonic Acid: A Review of its Use in Cosmetic Formulations. Journal of Cosmetic Science. 2014.

- Cosmetic Ingredient Review. Final Report on the Safety Assessment of Hydroxyethylpiperazine Ethane Sulfonic Acid. International Journal of Toxicology. 2008.

Octadecenedioic Acid

Other Names: Mediatone

Function: Emulsifying

1. Definition Octadecenedioic Acid:

Octadecenedioic Acid, also known as Octadec-9-enedioic acid or C18:1 diacid, is a naturally occurring unsaturated fatty acid with a molecular formula C18H32O4. It is commonly used in cosmetics for its skin brightening and anti-aging properties.

2. Use:

Octadecenedioic Acid is used in cosmetics as a skin lightening agent to reduce hyperpigmentation and even out skin tone. It is also known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in anti-aging products. Additionally, it helps to improve the overall texture and appearance of the skin.

3. Usage Octadecenedioic Acid:

Octadecenedioic Acid is typically found in skincare products such as serums, creams, and lotions. It is recommended to use products containing this ingredient as directed by the manufacturer. It is important to perform a patch test before using any new product to check for any potential allergic reactions. As with any skincare ingredient, it is advisable to consult with a dermatologist before incorporating Octadecenedioic Acid into your skincare routine.

4. References:

- Pumori Saokar Telang, Vishal K. Chavhan, Ashwini S. Patil, and Amit A. Telang. "Octadecenedioic acid: A review of its chemistry, pharmacology, and therapeutic potential." Journal of Applied Pharmaceutical Science 7, no. 6 (2017): 241-247.

- J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, A. M. Rios-Romero, and A. E. Marchat. "Octadecenedioic acid inhibits migration and invasion in human lung cancer cells." Biochemical and Biophysical Research Communications 506, no. 1 (2018): 52-59.

- A. E. Marchat, J. L. Lopez-Camarillo, L. M. Arechaga-Ocampo, R. Villegas-Sepulveda, A. Gonzalez-De la Rosa, and A. M. Rios-Romero. "Octadecenedioic acid inhibits proliferation and induces apoptosis in human lung cancer cells." Oncology Reports 40, no. 5 (2018): 2859-2867.

Toluene Sulfonic Acid

Other Names: Toluenesulfonic acid

Function: Solvent to dissolve substances insoluble in water, Surfactant

1. Definition Toluene Sulfonic Acid:

Toluene Sulfonic Acid, also known as tosylic acid, is a strong organic acid commonly used in the production of various chemicals and pharmaceuticals. It is a clear, colorless liquid with a pungent odor, and it is highly soluble in water.

2. Use:

Toluene Sulfonic Acid is often used as a catalyst in chemical reactions, particularly in the synthesis of esters, ethers, and other organic compounds. It can also be used as a pH adjuster in cosmetic formulations to help maintain the stability and effectiveness of the product.

3. Usage Toluene Sulfonic Acid:

When using Toluene Sulfonic Acid in cosmetics, it is important to follow proper safety precautions. This acid can be irritating to the skin, eyes, and respiratory system, so it should be handled with care. It is recommended to wear protective gloves, goggles, and a mask when working with Toluene Sulfonic Acid. Additionally, it should be used in a well-ventilated area to minimize exposure to fumes.

4. References:

- "Toluene Sulfonic Acid." PubChem, National Center for Biotechnology Information, pubchem.ncbi.nlm.nih.gov/compound/Toluene-sulfonic-acid.

- "Safety Data Sheet - Toluene Sulfonic Acid." Fisher Scientific, www.fishersci.com/shop/msdsproxy?storeId=10652&productName=Toluene+Sulfonic+Acid&productDescription=T2905&productCategory=ACROS&productID=AC222860250.

- "Toluene Sulfonic Acid in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/toluene-sulfonic-acid.

Alcohol Denat

Other Names: SD Alcohol; SD Alcohol 40; SD Alcohol 40B; Denatured Alcohol; Dehydrated Ethanol; Alcohol Denatured

Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent

1. Definition Alcohol Denat:

Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.

2. Use:

Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.

3. Usage Alcohol Denat:

When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.

4. References:

- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.

- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.

- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Water (Solvent)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Polyquaternium 10 (Antistatic Agent, Film Forming, Hair Fixing)
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1 4	B	Glycolic Acid (pH adjusting agent, pH adjusting agent, Exfoliant)	Anti Aging Bad for sensitive skin Good for oily skin
1	-	Methylpropanediol (Solvent)
1	A	Diisopropyl Adipate (Solvent, Masking, Fragrance, Skin Conditioning, Emollient, Plasticizer)
1	B	Capryloyl Salicylic Acid (Skin Conditioning)
1	-	Hydroxyethylpiperazine Ethane Sulfonic Acid (pH adjusting agent)
1	-	Octadecenedioic Acid (Emulsifying)	Cleansing
1	A	Toluene Sulfonic Acid (Solvent to dissolve substances insoluble in water, Surfactant)	Cleansing
4	-	Alcohol Denat (Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent)	Bad for sensitive skin Bad for dry skin Alcohol

SkinCeuticals Blemish Age Defense Salicylic Acid Acne Treatment

Ingredients

Analysis results of Ingredients

Ingredient List