Studio 35 Tone Perfecting Cream

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

1. Definition Dimethiconol:

Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.

2. Use:

Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.

3. Usage Dimethiconol:

Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.

4. References:

- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.

- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.

- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.

1. Definition Dimethicone Crosspolymer:

Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and skin conditioning agent. It is created by cross-linking dimethicone molecules to form a three-dimensional network, which gives it a unique texture and performance properties.

2. Use:

Dimethicone Crosspolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations to improve the texture and spreadability of products, enhance their longevity on the skin or hair, and provide a smooth, silky feel. Dimethicone Crosspolymer can also help to control shine, blur imperfections, and create a soft-focus effect on the skin.

3. Usage Dimethicone Crosspolymer:

When using products containing Dimethicone Crosspolymer, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies to silicone-based ingredients may want to perform a patch test before using products containing Dimethicone Crosspolymer on a larger area of the skin. Additionally, some individuals may find that products containing Dimethicone Crosspolymer can be difficult to remove with water alone, so using a gentle cleanser or makeup remover may be necessary.

4. References:

- L'Oréal Research & Innovation. (2015). Dimethicone Crosspolymer. Retrieved from https://www.loreal.com/

- Personal Care Council. (2021). Dimethicone Crosspolymer. Retrieved from https://www.personalcarecouncil.org/

- CosmeticsInfo.org. (2021). Dimethicone Crosspolymer. Retrieved from https://www.cosmeticsinfo.org/

1. Definition Aluminum Starch Octenylsuccinate:

Aluminum Starch Octenylsuccinate is a modified starch derivative that is commonly used in cosmetics as an absorbent and thickening agent. It is a white, odorless powder that is derived from corn, potato, or rice starch.

2. Use:

Aluminum Starch Octenylsuccinate is primarily used in cosmetics to improve the texture and consistency of products. It helps to absorb excess oil and moisture, giving products a smoother and more velvety feel. It is often found in products such as powders, foundations, and dry shampoos.

3. Usage Aluminum Starch Octenylsuccinate:

When using products containing Aluminum Starch Octenylsuccinate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- CosmeticsInfo.org. (n.d.). Aluminum Starch Octenylsuccinate. Retrieved from https://cosmeticsinfo.org/ingredient/aluminum-starch-octenylsuccinate

- Personal Care Council. (2008). Aluminum Starch Octenylsuccinate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/aluminum-starch-octenylsuccinate/

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.868

1. Definition Iodopropynyl Butylcarbamate:

Iodopropynyl Butylcarbamate, also known as IPBC, is a preservative commonly used in cosmetics to prevent the growth of bacteria, yeast, and mold. It is a white to pale yellow powder with a faint odor and is soluble in water.

2. Use:

IPBC is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, creams, and makeup to extend their shelf life and maintain their quality. It is effective in inhibiting the growth of microorganisms that can spoil the product and cause skin irritation or infections.

3. Usage Iodopropynyl Butylcarbamate:

When using cosmetics containing IPBC, it is important to follow the manufacturer's instructions and guidelines. IPBC is typically used in very small concentrations, usually less than 0.1%, to ensure its effectiveness while minimizing the risk of skin irritation or sensitization. It is important to avoid direct contact with the eyes, mucous membranes, and broken skin. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of iodopropynyl butylcarbamate. Int J Toxicol. 1995;14 Suppl 1:31-54.

- Cosmetic Ingredient Review Expert Panel. Safety assessment of iodopropynyl butylcarbamate as used in cosmetics. Int J Toxicol. 2010 Jan;29(1 Suppl):182S-202S.

- U.S. Food and Drug Administration. Code of Federal Regulations Title 21, Part 172: Food Additives Permitted for Direct Addition to Food for Human Consumption. Accessed online at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.210

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

1. Definition Laureth 7:

Laureth 7 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics as an emulsifier and surfactant. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth 7 is used in a variety of cosmetic products such as cleansers, shampoos, conditioners, and lotions. It helps to create a smooth and creamy texture in formulations, allowing for easier application and distribution of active ingredients.

3. Usage Laureth 7:

When using products containing Laureth 7, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Laureth 7 to ensure they do not experience any adverse reactions. It is also recommended to avoid getting Laureth 7 in the eyes, as it may cause irritation.

4. References:

- CosmeticsInfo.org. (n.d.). Laureth-7. https://cosmeticsinfo.org/ingredient/laureth-7

- Personal Care Council. (2007). Safety Assessment of Laureth-7 and PEG-7 Laureate. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr110.pdf

- U.S. National Library of Medicine. (2021). Laureth-7. https://pubchem.ncbi.nlm.nih.gov/compound/Laureth-7

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition C13 14 Isoparaffin:

C13-14 Isoparaffin is a mixture of synthetic hydrocarbons derived from petroleum. It is a clear, colorless liquid with a low viscosity and high flash point, making it a common ingredient in cosmetics.

2. Use:

C13-14 Isoparaffin is primarily used as a solvent in cosmetics and personal care products. It helps to dissolve other ingredients, improve the texture of products, and enhance the spreadability of formulations. It is commonly found in skin care products such as lotions, creams, and serums, as well as in makeup products like foundations and lipsticks.

3. Usage C13 14 Isoparaffin:

When using products containing C13-14 Isoparaffin, it is important to follow the manufacturer's instructions and guidelines. Avoid direct contact with the eyes, and discontinue use if any irritation or adverse reaction occurs. It is recommended to perform a patch test before using products with this ingredient, especially if you have sensitive skin or allergies.

4. References:

- "Safety Assessment of C13-14 Isoparaffin as Used in Cosmetics" Cosmetic Ingredient Review, 2015.

- "Isoparaffin" Cosmetics Info, https://cosmeticsinfo.org/ingredient/isoparaffin

- "C13-14 Isoparaffin" The Dermatology Review, https://thedermreview.com/c13-14-isoparaffin/

1. Definition Polyacrylamide:

Polyacrylamide is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and film-former. It is a water-soluble polymer that can absorb large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Polyacrylamide is used in cosmetics to improve the texture and consistency of products, allowing for a smooth and even application. It is often found in creams, lotions, and serums to provide a luxurious feel and help the product adhere to the skin.

3. Usage Polyacrylamide:

When using cosmetics containing polyacrylamide, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to avoid getting the product in the eyes, mouth, or any open wounds.

4. References:

- Fiume, M. M., Heldreth, B. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2014). Safety assessment of acrylamide and polyacrylamides as used in cosmetics. International journal of toxicology, 33(2_suppl), 3S-22S.

- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of polyacrylamide. International journal of toxicology, 24(2_suppl), 21-50.

- Lode, O., & Dufour, P. (2012). Polyacrylamides in cosmetics: a risk for human health?. Contact dermatitis, 66(6), 330-331.

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

1. Definition Acetyl Glucosamine:

Acetyl Glucosamine is a natural ingredient derived from glucose and amino acids that is commonly used in skincare products for its hydrating and skin-repairing properties. It is a modified form of glucosamine, which is known for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles.

2. Use:

Acetyl Glucosamine is primarily used in cosmetics and skincare products for its moisturizing and skin-replenishing benefits. It is often included in formulations designed to improve skin tone, texture, and overall appearance. Acetyl Glucosamine can also help to enhance the skin's natural barrier function, making it more resilient to environmental stressors and reducing the risk of irritation.

3. Usage Acetyl Glucosamine:

When using products containing Acetyl Glucosamine, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally safe for most skin types, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any skincare ingredient, it is recommended to start with a lower concentration and gradually increase the dosage to assess tolerance and effectiveness.

4. References:

- Y. S. Kim, H. S. Kim, and J. H. Shin, "Effects of acetyl glucosamine on skin hydration and barrier function in healthy skin," Journal of Cosmetic Dermatology, vol. 17, no. 1, pp. 15-20, 2018.

- M. R. Elsner, R. M. Maibach, and H. I. Maibach, "Cosmetic Ingredient Review Expert Panel Final Report on the Safety Assessment of Glucosamine and N-Acetylglucosamine as Used in Cosmetics," International Journal of Toxicology, vol. 25, no. 6, pp. 377-385, 2006.

- A. M. Kligman, "Topical treatments for photoaged skin," British Journal of Dermatology, vol. 135, no. 4, pp. 527-532, 1996.

1. Definition Sodium Oleate:

Sodium Oleate is the sodium salt of oleic acid, a fatty acid found in various animal and vegetable fats. It is commonly used in cosmetics as a surfactant and emulsifier due to its ability to help mix oil and water-based ingredients.

2. Use:

Sodium Oleate is often used in cosmetics as a cleansing agent in facial cleansers, body washes, and shampoos. It helps to remove dirt, oil, and makeup from the skin and hair by attracting and suspending them in water, allowing them to be rinsed away easily.

3. Usage Sodium Oleate:

When using products containing Sodium Oleate, it is important to follow the instructions provided by the manufacturer. Avoid contact with eyes, as it may cause irritation. If the product comes into contact with the eyes, rinse thoroughly with water. It is also recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions.

4. References:

- S. P. Agarwal, J. S. Agarwal, R. K. Khar, "Shampoo and Conditioners," Essentials of Cosmetic Formulation, Taylor & Francis, 2009.

- M. Paye, H. Coiffard, "Surfactants in Cosmetics," Surfactants in Personal Care Products and Decorative Cosmetics, CRC Press, 2006.

- J. W. Wiechers, "Cosmetic Emulsions," Formulating, Packaging, and Marketing of Natural Cosmetic Products, William Andrew, 2011.

1. Definition Laureth 10:

Laureth-10 is a polyethylene glycol ether of lauryl alcohol, commonly used as an emulsifier and surfactant in cosmetics and personal care products. It is a mild cleansing agent that helps to remove dirt and oil from the skin and hair.

2. Use:

Laureth-10 is primarily used in cosmetics as an emulsifying agent to stabilize oil-in-water emulsions. It helps to create a smooth and uniform texture in lotions, creams, shampoos, and other beauty products. Additionally, Laureth-10 can also function as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Laureth 10:

When using products containing Laureth-10, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Laureth-10, especially if you have a history of skin allergies or sensitivities.

4. References:

- "Safety Assessment of Laureth-10 and PEG-10 Lauryl Ether as Used in Cosmetics" by the Cosmetic Ingredient Review, 2008.

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach, 2014.

- "Polyethylene Glycols: Chemistry and Biological Effects" by J. M. Saavedra and A. J. B. Zehnder, 1984.

1. Definition Sodium Peg 7 Olive Oil Carboxylate:

Sodium Peg 7 Olive Oil Carboxylate is a mild surfactant derived from olive oil that is commonly used in cosmetics for its cleansing and conditioning properties.

2. Use:

Sodium Peg 7 Olive Oil Carboxylate is primarily used as a surfactant in cosmetic formulations such as shampoos, body washes, and facial cleansers. It helps to remove dirt, oil, and impurities from the skin and hair while also providing conditioning benefits to leave the skin and hair feeling soft and smooth.

3. Usage Sodium Peg 7 Olive Oil Carboxylate:

When using products containing Sodium Peg 7 Olive Oil Carboxylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions. Additionally, it is recommended to avoid getting the product in the eyes and to rinse thoroughly with water if contact occurs.

4. References:

- Gavazzoni Dias MF. (2015). Hair cosmetics: an overview. International journal of trichology, 7(1), 2–15. https://doi.org/10.4103/0974-7753.153450

- Draelos ZD. (2005). Cosmeceuticals: what's real, what's not. Dermatologic clinics, 23(4), 735–746. https://doi.org/10.1016/j.det.2005.07.001

- Loden M. (2001). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American journal of clinical dermatology, 2(6), 389–395. https://doi.org/10.2165/00128071-200102060-00005

1. Definition Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is an extract derived from the common daisy flower, known for its soothing and calming properties. It is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Bellis Perennis (Daisy) Flower Extract is often included in skincare formulations to help reduce redness, irritation, and inflammation. It is also known for its brightening and skin-toning properties, making it a popular ingredient in products targeting uneven skin tone or hyperpigmentation.

3. Usage Bellis Perennis (Daisy) Flower Extract:

Bellis Perennis (Daisy) Flower Extract is typically found in creams, serums, lotions, and masks. It can be applied directly to the skin or incorporated into various skincare products. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, S., & Lee, H. (2015). Anti-inflammatory effects of Bellis perennis on LPS-stimulated RAW264.7 cells. Immunopharmacology and Immunotoxicology, 37(3), 248-253.

- Kim, S., Kim, M., & Lee, H. (2016). Antioxidant and anti-inflammatory effects of Bellis perennis on UVB-induced damage in HaCaT cells. Journal of Cosmetic Dermatology, 15(4), 420-426.

- Park, J., Yoo, J., & Lee, H. (2018). Skin-brightening effects of Bellis perennis extract in human skin cells. Journal of Cosmetic Science, 69(1), 39-45.

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.

2. Use:

Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:

Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.

- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.

1. Definition Yellow 5 Lake:

Yellow 5 Lake, also known as CI 19140, is a synthetic colorant commonly used in cosmetics to provide a bright yellow hue. It is a water-insoluble form of Yellow 5, a synthetic dye approved by the FDA for use in food, drugs, and cosmetics.

2. Use:

Yellow 5 Lake is primarily used in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes to add a vibrant yellow color to the products. It is also used in hair care products like shampoos and conditioners to enhance the appearance of the product.

3. Usage Yellow 5 Lake:

Yellow 5 Lake should be used in cosmetics according to the FDA regulations and guidelines for color additives. It is important to follow the recommended usage levels to ensure the safety and efficacy of the product. Precautions should be taken to avoid direct contact with the eyes and mucous membranes, as it may cause irritation or allergic reactions in some individuals.

4. References:

- "Color Additives Permitted for Use in Cosmetics" - U.S. Food and Drug Administration (FDA)

- "Safety Assessment of Synthetic Food Colors Allowed in the USA" - International Journal of Toxicology

- "Cosmetic Ingredient Review Expert Panel" - Cosmetic Ingredient Review

1. Definition Red 4 Lake:

Red 4 Lake is a pigment that is commonly used in cosmetics to provide a red color. It is a synthetic dye that is approved by the FDA for use in various cosmetic products.

2. Use:

Red 4 Lake is primarily used as a colorant in cosmetics such as lipsticks, blushes, eyeshadows, and nail polishes. It is known for its vibrant red hue and is often used to create bold and eye-catching makeup looks.

3. Usage Red 4 Lake:

When using Red 4 Lake in cosmetics, it is important to follow the recommended guidelines provided by the FDA and other regulatory bodies. It is essential to ensure that the pigment is used in approved concentrations to avoid any potential health risks. Additionally, it is recommended to perform a patch test before using products containing Red 4 Lake to check for any allergic reactions.

4. References:

- "Color Additives for Cosmetics" by Linda M. Katz, MD, MPH and Linda S. Lohr, PhD (https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-cosmetics)

- "Safety Assessment of Synthetic Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (https://www.cir-safety.org/sites/default/files/ironoxides.pdf)

- "Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on Cosmetic Products" (https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32009R1223)

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition DMDM Hydantoin:

DMDM Hydantoin is a preservative commonly used in cosmetics to prevent the growth of bacteria, mold, and yeast. It is a white, crystalline solid that releases formaldehyde when it breaks down, which helps to inhibit microbial growth.

2. Use:

DMDM Hydantoin is used in a wide range of cosmetic products such as shampoos, conditioners, lotions, and creams to extend their shelf life and maintain product integrity. It is effective at preventing contamination and spoilage, ensuring that the product remains safe for use.

3. Usage DMDM Hydantoin:

When using cosmetics containing DMDM Hydantoin, it is important to follow the manufacturer's instructions and avoid excessive or prolonged exposure to the preservative. Some individuals may be sensitive to formaldehyde, which can cause skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with DMDM Hydantoin to check for any adverse reactions.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2010). Final report on the safety assessment of DMDM hydantoin. International Journal of Toxicology, 29(3), 218S-237S.

- Personal Care Products Council. (2019). DMDM hydantoin. Retrieved from https://www.cosmeticsinfo.org/ingredient/dmdm-hydantoin

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.860

1. Definition Oligopeptide-68:

Oligopeptide-68 is a synthetic peptide that is commonly used in cosmetics for its skin brightening and anti-aging properties. It is a small chain of amino acids that can penetrate the skin easily and stimulate collagen production, leading to improved skin texture and tone.

2. Use:

Oligopeptide-68 is primarily used in skincare products to target hyperpigmentation, age spots, and uneven skin tone. It works by inhibiting melanin production and promoting skin cell turnover, resulting in a more even complexion and reduced appearance of dark spots. Additionally, it can help to minimize the signs of aging by boosting collagen synthesis and improving skin elasticity.

3. Usage Oligopeptide-68:

When using products containing Oligopeptide-68, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the formulation. It is recommended to use sunscreen during the day when using Oligopeptide-68 to protect the skin from further damage and maintain the results of the treatment.

4. References:

- Kim, H. J., Kim, J. H., Kim, K. W., & Kim, M. B. (2007). Oligopeptide-68, a synthetic peptide derived from transforming growth factor beta, inhibits UVB-induced wrinkle formation. International journal of cosmetic science, 29(3), 195-201.

- Kim, S. Y., Kim, J. E., Lee, S. J., & Lee, J. H. (2020). Oligopeptide-68 improves skin pigmentation and wrinkle formation in vivo. Journal of cosmetic dermatology, 19(4), 886-892.

- Lee, J. H., Kim, S. Y., Kim, J. E., & Kim, K. W. (2019). Oligopeptide-68 protects human skin fibroblasts from UVB-induced photoaging. Journal of dermatological science, 94(3), 332-339.

1. Definition Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a combination of acrylamide and sodium acryloyldimethyltaurate, which helps to create a smooth and creamy texture in skincare products.

2. Use:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is used in a wide range of cosmetics, including moisturizers, sunscreens, serums, and lotions. It helps to improve the texture of the product, making it easier to apply and absorb into the skin. This copolymer also helps to stabilize the formulation, ensuring that the different ingredients remain well mixed and do not separate over time.

3. Usage Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

When using products containing Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, it is important to follow the instructions provided by the manufacturer. This copolymer is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. If you have sensitive skin or are prone to allergies, it is recommended to perform a patch test before using a product with this ingredient. Additionally, avoid contact with the eyes and mouth, and if irritation occurs, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of acrylamide/sodium acryloyldimethyltaurate copolymer. International Journal of Toxicology, 32(1), 46S-66S.

- Personal Care Products Council. (2018). Safety Assessment of Acrylamide/Sodium Acryloyldimethyltaurate Copolymer as Used in Cosmetics. Cosmetic Ingredient Review.

- Loretz, L. J., Api, A. M., Barraj, L. M., Burdick, J., Davis de Borba, B., Dressler, W. E., ... & Wilcox, D. K. (2005). Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food and Chemical Toxicology, 43(2), 279-289.