THE FACE SHOP Yehwadam Hwansaenggo Rejuvenating Radiance Serum

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Polyglyceryl 3 Methylglucose Distearate:

Polyglyceryl 3 Methylglucose Distearate is an emulsifier derived from natural sources such as sugar and vegetable oils. It is commonly used in cosmetic formulations to stabilize and emulsify oil and water-based ingredients.

2. Use:

Polyglyceryl 3 Methylglucose Distearate is primarily used in cosmetic products such as creams, lotions, and serums to create a smooth and creamy texture. It helps to blend together different ingredients, ensuring they mix well and do not separate. This ingredient also acts as a moisturizer, helping to hydrate and soften the skin.

3. Usage Polyglyceryl 3 Methylglucose Distearate:

When using products containing Polyglyceryl 3 Methylglucose Distearate, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-3 Methylglucose Distearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." Truth in Aging, www.truthinaging.com/ingredients/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." The Derm Review, www.thedermreview.com/polyglyceryl-3-methylglucose-distearate/.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

1. Definition Ceteareth 6 Olivate:

Ceteareth 6 Olivate is a combination of Ceteareth-6, a blend of cetyl and stearyl alcohol ethoxylated with 6 moles of ethylene oxide, and Olivate, an ester of olive oil and fatty alcohol. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Ceteareth 6 Olivate is primarily used in skincare products such as creams, lotions, and serums to stabilize oil-water emulsions. It helps to create a smooth and uniform texture in formulations, allowing for better spreadability and absorption of active ingredients into the skin. Additionally, it can also act as a mild cleansing agent, helping to remove dirt and impurities from the skin.

3. Usage Ceteareth 6 Olivate:

When using products containing Ceteareth 6 Olivate, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation or allergic reactions occur, discontinue use immediately.

4. References:

- "Ceteareth-6 Olivate" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/ceteareth-6-olivate

- "Ceteareth-6 Olivate" The Derm Review, https://thedermreview.com/ceteareth-6-olivate/

- "Ceteareth-6 Olivate" Truth In Aging, https://www.truthinaging.com/ingredients/ceteareth-6-olivate

1. Definition Dipentaerythrityl Hexa C5 9 Acid Esters:

Dipentaerythrityl Hexa C5-9 Acid Esters are a group of esters derived from the reaction of dipentaerythritol with a mixture of C5-9 carboxylic acids. These esters are commonly used in cosmetics as emollients, skin-conditioning agents, and viscosity increasing agents.

2. Use:

Dipentaerythrityl Hexa C5-9 Acid Esters are used in cosmetic formulations to provide a smooth and soft feel to the skin. They help to moisturize and condition the skin, leaving it feeling hydrated and supple. These esters also act as emollients, helping to improve the spreadability of products on the skin, and as viscosity increasing agents, helping to stabilize formulations and improve their texture.

3. Usage Dipentaerythrityl Hexa C5 9 Acid Esters:

Dipentaerythrityl Hexa C5-9 Acid Esters are typically used in a wide range of cosmetic products, including moisturizers, lotions, creams, sunscreens, and makeup products. They are generally considered safe for use in cosmetics, but it is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product. It is also advisable to perform a patch test before using products containing these esters to check for any potential allergic reactions.

4. References:

- Cosmetics Info. (n.d.). Dipentaerythrityl Hexa C5-9 Acid Esters. https://cosmeticsinfo.org/ingredient/dipentaerythrityl-hexa-c5-9-acid-esters

- Personal Care Council. (2019). Dipentaerythrityl Hexa C5-9 Acid Esters. https://www.personalcarecouncil.org/ingredient-dictionary/dipentaerythrityl-hexa-c5-9-acid-esters/

- The European Commission. (2021). Cosmetic Ingredient Database (Cosing). https://ec.europa.eu/growth/tools-databases/cosing/

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract:

Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract is a natural ingredient derived from the fruit of the sea buckthorn plant. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Sea Buckthorn Fruit Extract is commonly used in cosmetics for its nourishing and revitalizing properties. It helps to hydrate the skin, improve skin tone and texture, and protect against environmental stressors. It is often found in moisturizers, serums, and anti-aging products.

3. Usage Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract:

When using products containing Sea Buckthorn Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on the entire face. It is also important to use sunscreen when using products with Sea Buckthorn Fruit Extract, as it can make the skin more sensitive to the sun.

4. References:

- Kim, J. H., Lee, H. J., Jeong, S. J., Lee, M. H., & Kim, S. H. (2009). Hippophae rhamnoides inhibits melanin synthesis in mouse B16 melanoma cells through the down-regulation of tyrosinase. Food and Chemical Toxicology, 47(1), 165-170.

- Yang, B., Kalimo, K. O., Mattila, L. M., Kallio, S. E., & Katajisto, J. K. (2000). Effects of dietary supplementation with sea buckthorn (Hippophaë rhamnoides) seed and pulp oils on atopic dermatitis. Journal of Nutritional Biochemistry, 11(6), 338-340.

- Gupta, A., Kumar, R., & Pal, K. (2008). Sea buckthorn (Hippophae rhamnoides L.) leaf extract ameliorates the gamma radiation mediated DNA damage and hepatic alterations. Food and Chemical Toxicology, 46(7), 2410-2419.

Definition Salix Alba (Willow) Bark Extract:

Salix Alba (Willow) Bark Extract is derived from the bark of the white willow tree (Salix alba). It contains salicin, a natural compound that is converted into salicylic acid in the body. Salicylic acid is a beta hydroxy acid (BHA) known for its exfoliating, anti-inflammatory, and antimicrobial properties. Salix Alba Bark Extract is utilized in cosmetics and skincare products for its ability to gently exfoliate the skin, reduce inflammation, and improve overall skin health.

Use and Usage Salix Alba (Willow) Bark Extract:

Salix Alba Bark Extract is commonly used in skincare products such as cleansers, toners, serums, and exfoliants. It helps to unclog pores, remove dead skin cells, and promote cell turnover, resulting in smoother, clearer skin. Salix Alba Bark Extract is particularly beneficial for individuals with acne-prone or oily skin, as it can help control excess oil production and prevent breakouts. Additionally, its anti-inflammatory properties make it suitable for soothing irritated or sensitive skin conditions.

Precautions When Using:

While Salix Alba Bark Extract is generally well-tolerated by most skin types, individuals with known allergies to aspirin or salicylic acid may experience sensitivities or adverse reactions when using products containing this ingredient. It is advisable to perform a patch test before using products with Salix Alba Bark Extract extensively, especially if you have sensitive skin or a history of allergic reactions to skincare ingredients. Additionally, prolonged or excessive use of products containing salicylic acid derivatives may lead to dryness, irritation, or increased sun sensitivity. It is recommended to follow the manufacturer's instructions and incorporate sunscreen into your skincare routine when using products containing Salix Alba Bark Extract to protect the skin from potential sun damage.

References:

1. Garg, S., & Mehta, A. (2016). Evaluation of anti-inflammatory activity of Salix alba Linn. (White Willow Bark). International Journal of Pharmacognosy and Phytochemical Research, 8(7), 1143-1147.

2. Jung, H. A., Kim, J. E., & Chung, H. Y. (2008). Chin YW. ACE inhibitors from Salix glandulosa.* Arch Pharm Res, 31(12), 1517-1522.

3. Gfeller, H., & Böni, R. (1995). Acne vulgaris: current concepts in the pathogenesis and treatment. Dermatology, 191(1), 1-7.

1. Definition Panax Ginseng Root Extract:

Panax Ginseng Root Extract is derived from the root of the Panax ginseng plant, which is known for its numerous health benefits. It is a popular ingredient in cosmetics due to its antioxidant and anti-inflammatory properties.

2. Use:

Panax Ginseng Root Extract is commonly used in skincare products for its ability to promote skin hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to help brighten the skin and even out skin tone, making it a popular choice for anti-aging and brightening products.

3. Usage Panax Ginseng Root Extract:

When using skincare products containing Panax Ginseng Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also important to use sunscreen when using products containing Panax Ginseng Root Extract, as it can increase skin sensitivity to the sun.

4. References:

- Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Meridian Stud. 2011;4(2):85-97.

- Kim S, Shin BC, Lee MS, Lee H, Ernst E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr Med. 2011;17(12):937-944.

- Kim HG, Cho JH, Yoo SR, et al. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8(4):e61271.

1. Definition Phellinus Linteus Extract:

Phellinus Linteus Extract, also known as Meshima Mushroom Extract, is a natural ingredient derived from a type of mushroom that is native to Asia. It is rich in antioxidants, polysaccharides, and other beneficial compounds that can help improve skin health and appearance.

2. Use:

Phellinus Linteus Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin brightening properties. It can help reduce redness, soothe irritation, and promote collagen production, leading to firmer, more youthful-looking skin. Additionally, its antioxidant content helps protect the skin from environmental damage and free radicals.

3. Usage Phellinus Linteus Extract:

Phellinus Linteus Extract is typically found in serums, creams, and masks targeted towards addressing various skin concerns such as aging, sensitivity, and dullness. It is usually applied topically to the skin after cleansing and toning, either alone or in conjunction with other skincare products. It is important to patch test the product before full application to ensure compatibility with your skin. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating Phellinus Linteus Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, S. H., Lee, S. E., Oh, H., Kim, M., & Nam, K. S. (2011). The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology and Immunotoxicology, 33(4), 717-726.

- Lee, I. K., Han, M. S., Lee, M. S., Kim, Y. S., & Yun, B. S. (2012). Styrylpyrone-class compounds from medicinal fungi Phellinus and Inonotus spp., and their medicinal importance. Current Medicinal Chemistry, 19(21), 3708-3728.

- Choi, Y. H., Bae, J. K., Chae, H. S., Kim, Y. O., Park, J. K., Lee, K. J., ... & Kim, J. H. (2010). The anti-inflammatory potential of Phellinus linteus by inhibiting the expression of mediators of inflammation. Immune Network, 10(5), 137-143.

1. Definition Ganoderma Lucidum (Mushroom) Extract:

Ganoderma Lucidum Extract, also known as Reishi Mushroom Extract, is a natural ingredient derived from the Ganoderma Lucidum mushroom. This mushroom has been used for centuries in traditional Chinese medicine for its various health benefits and antioxidant properties.

2. Use:

Ganoderma Lucidum Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin-soothing properties. It is known to help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote overall skin health. Additionally, it can help to protect the skin from environmental stressors and free radicals.

3. Usage Ganoderma Lucidum (Mushroom) Extract:

Ganoderma Lucidum Extract can be found in various skincare products such as serums, creams, and masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating any new skincare ingredient into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Cheung, J.K.H., Li, J., Cheung, A.W.H., Zhu, K.Y., Wong, J.Y.H., Chan, K.M., & Fung, K.P. (2012). Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. Neurochemical Research, 37(8), 1751-1762.

- Lin, Z.B. (2006). Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum. Journal of Pharmacological Sciences, 100(5), 500-517.

- Gao, Y., Zhou, S., Jiang, W., Huang, M., & Dai, X. (2003). Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunological Investigations, 32(3), 201-215.

1. Definition Paeonia Suffruticosa Branch/Flower/Leaf Extract:

Paeonia Suffruticosa Branch/Flower/Leaf Extract is an extract derived from the peony plant, specifically from its branches, flowers, and leaves. Peony extract is known for its anti-inflammatory, antioxidant, and skin brightening properties, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Branch/Flower/Leaf Extract is commonly used in cosmetics and skincare products for its various benefits. It can help to reduce redness and inflammation, protect the skin from free radical damage, and improve overall skin tone and texture. Peony extract is often included in products targeting sensitive skin, aging skin, and hyperpigmentation.

3. Usage Paeonia Suffruticosa Branch/Flower/Leaf Extract:

When using products containing Paeonia Suffruticosa Branch/Flower/Leaf Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. If any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- Lee, H. J., Lee, H. J., Lee, E. O., Lee, J. H., Lee, K. S., Kim, K. H., ... & Kim, S. H. (2010). In vivo anti-inflammatory and antinociceptive effects of paeonol in experimental rodents. Archives of pharmacal research, 33(7), 1105-1112.

- Kim, D. S., Lee, H. J., & Jeon, Y. D. (2018). Anti-inflammatory effects of paeonol on LPS-stimulated RAW264. 7 cells. Acta Pharmaceutica Sinica B, 8(3), 440-447.

- Kim, M. J., Kim, H. J., Kim, D. H., Kang, K. H., & Kim, B. H. (2018). Anti-aging and skin protective effects of a peony extract from Paeonia suffruticosa. Journal of cosmetic dermatology, 17(6), 1123-1130.

1. Definition Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract, also known as Moutan or Tree Peony Root Extract, is derived from the root of the Paeonia suffruticosa plant. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Root Extract is commonly used in cosmetics for its various skincare benefits. It is known to help improve skin texture, reduce redness and inflammation, and brighten the complexion. Additionally, this extract has been found to have anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Paeonia Suffruticosa Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee JH, Kim GH. Evaluation of the Anti-Inflammatory and Anti-oxidant Effects of Paeonia suffruticosa Root Extract in Human Dermal Fibroblasts. Int J Mol Sci. 2015;16(3):6422-6435. doi:10.3390/ijms16036422

- Li Z, Li J, Ma H, et al. Paeonia suffruticosa Andr. and its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-inflammatory activity in activated microglia. J Ethnopharmacol. 2018;211:285-294. doi:10.1016/j.jep.2017.08.015

- Kim JH, Kim YS, Song GY, Kim WH. Antiwrinkle effect of Paeonia suffruticosa. J Cosmet Sci. 2006;57(2):121-130.

1. Definition Polygonum Multiflorum Root Extract:

Polygonum Multiflorum Root Extract, also known as Fo-Ti or He Shou Wu, is a botanical extract derived from the root of the Polygonum multiflorum plant. It has been used in traditional Chinese medicine for centuries due to its various health benefits.

2. Use:

Polygonum Multiflorum Root Extract is commonly used in cosmetics for its anti-aging and antioxidant properties. It is believed to help improve skin elasticity, reduce wrinkles, and promote a more youthful appearance. Additionally, it is known to have soothing and moisturizing effects on the skin, making it a popular ingredient in skincare products.

3. Usage Polygonum Multiflorum Root Extract:

When using cosmetics containing Polygonum Multiflorum Root Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. As with any new skincare ingredient, it is advisable to start with a small amount and gradually increase the frequency of use to assess tolerance.

4. References:

- Shin, S., Lee, S., Kwon, J., Moon, S., Lee, C., Lee, A., & Moon, J. (2018). Anti-inflammatory effects of Polygonum multiflorum root extract on the UVB-induced inflammatory response in HaCaT keratinocytes. Journal of Ethnopharmacology, 220, 87-95.

- Zhang, J., Zhang, Y., & Zhang, X. (2017). Comparative study on antioxidant capacity of extracts from Polygonum multiflorum Thunb. and its endophytic fungus. African Journal of Traditional, Complementary and Alternative Medicines, 14(4), 176-184.

- Song, H., Kim, W., Kim, J., Lee, K., Son, H., & Kim, J. (2019). Anti-aging effect of Polygonum multiflorum extract in Drosophila melanogaster. Journal of Applied Biological Chemistry, 62(3), 281-287.

1. Definition Poria Cocos Sclerotium Extract:

Poria Cocos Sclerotium Extract is a natural ingredient derived from the sclerotium of Poria cocos, a type of fungus found in Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Poria Cocos Sclerotium Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in moisturizers, serums, and masks to help improve the overall health and appearance of the skin. Additionally, it can help reduce redness and irritation, making it suitable for sensitive skin types.

3. Usage Poria Cocos Sclerotium Extract:

When using skincare products containing Poria Cocos Sclerotium Extract, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product should be applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions.

4. References:

- Lee, J. H., Kim, E. H., & Kim, H. S. (2014). Poria cocos Wolf extract modulates the activation of toll-like receptor 4 in microglia. Experimental and therapeutic medicine, 8(1), 265-270.

- Wang, L., Zhang, Y., Wang, Z., & Gong, N. (2019). Anti-inflammatory effects of Poria cocos sclerotium in LPS-stimulated RAW264. 7 cells. Experimental and therapeutic medicine, 18(1), 579-586.

- Zhao, Q., Yang, F., Meng, L., Wang, L., & Wang, M. (2018). Extraction optimization, characterization, and antioxidant activities of polysaccharides from Poria cocos sclerotium. International journal of biological macromolecules, 120, 1700-1707.

1. Definition Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is a natural ingredient derived from the root of the Rehmannia glutinosa plant, which is native to East Asia. This extract is known for its anti-inflammatory, antioxidant, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Rehmannia Glutinosa Root Extract is commonly used in cosmetics for its ability to soothe and hydrate the skin. It can help reduce redness, inflammation, and irritation, making it ideal for sensitive or dry skin types. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is typically found in creams, serums, and masks. It can be applied directly to the skin as part of a skincare routine, either on its own or in combination with other ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using the extract to ensure compatibility with your skin.

4. References:

- Kim, S. H., Kim, S. H., Park, S., & Lee, J. H. (2018). Anti-Inflammatory Effects of Rehmannia glutinosa Libosch Extract in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Nutrients, 10(10), 1531.

- Choi, H. J., Chung, T. W., Park, M. J., & Choi, H. J. (2017). Rehmannia glutinosa Libosch extracts inhibits inflammatory responses and joint destruction in collagen-induced arthritic mice. Journal of Ethnopharmacology, 196, 126-132.

- Lee, S., Kim, M. G., Ko, Y. S., Lee, J. H., & Kim, H. K. (2020). Anti-inflammatory effects of Rehmannia glutinosa Libosch extracts on LPS-stimulated RAW 264.7 cells. Journal of Microbiology and Biotechnology, 30(3), 429-437.

1. Definition Angelica Gigas Extract:

Angelica Gigas Extract is a natural ingredient derived from the roots of the Angelica Gigas plant, also known as Korean Angelica. It is commonly used in skincare products for its anti-inflammatory and antioxidant properties.

2. Use:

Angelica Gigas Extract is often included in cosmetics for its ability to help improve skin texture, reduce redness and irritation, and protect against environmental stressors. It is also known for its potential to brighten and even out skin tone, making it a popular ingredient in anti-aging and brightening skincare products.

3. Usage Angelica Gigas Extract:

When using cosmetics containing Angelica Gigas Extract, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or sensitivities. As with any new skincare ingredient, it is best to introduce it gradually into your routine to monitor how your skin responds.

4. References:

- Lee, S. H., et al. (2012). Angelica gigas ameliorate inflammatory response via suppression of nuclear factor-κB and mitogen-activated protein kinase activity. Journal of Ethnopharmacology, 140(3), 604-611.

- Kim, J. Y., et al. (2017). Anti-inflammatory effects of Angelica gigas extract in atherosclerosis-prone mice. Molecular Medicine Reports, 16(4), 4331-4338.

- Park, S. H., et al. (2015). Angelica gigas Nakai extract inhibits lipopolysaccharide-induced inflammatory response. International Journal of Molecular Medicine, 36(6), 1647-1656.

1. Definition Trichosanthes Kirilowii Root Extract:

Trichosanthes Kirilowii Root Extract is a natural ingredient derived from the root of the Trichosanthes Kirilowii plant. This extract is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Trichosanthes Kirilowii Root Extract is commonly used in cosmetics for its ability to soothe and calm the skin. It is often found in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is believed to have anti-aging benefits, helping to improve the overall appearance of the skin.

3. Usage Trichosanthes Kirilowii Root Extract:

When using skincare products containing Trichosanthes Kirilowii Root Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to do a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. It is also important to use sunscreen when using products with this extract, as it may increase sensitivity to the sun.

4. References:

- Lee, J. H., Lee, J. Y., Kim, H. G., Kim, Y. S., & Kim, D. S. (2013). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Breast Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2013, 975350. https://doi.org/10.1155/2013/975350

- Park, J. H., Kim, H. G., Kim, Y. S., & Kim, D. S. (2015). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Prostate Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2015, 191031. https://doi.org/10.1155/2015/191031

- Kim, H. G., Kim, Y. S., & Kim, D. S. (2013). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Lung Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2013, 652867. https://doi.org/10.1155/2013/652867

1. Definition Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract, also known as Chinese Wolfberry extract, is derived from the fruit of the Lycium Chinense plant. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Lycium Chinense Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, this extract has soothing and hydrating properties, making it suitable for all skin types.

3. Usage Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this extract into your skincare routine, apply products containing Lycium Chinense Fruit Extract onto clean skin, following the directions provided by the manufacturer. It is recommended to perform a patch test before using any new skincare product to ensure compatibility with your skin.

4. References:

- Lee, J. S., Kim, H. J., Lee, Y. J., & Kim, J. (2016). Protective effect of Lycium chinense fruit on carbon tetrachloride-induced hepatotoxicity. Experimental and therapeutic medicine, 11(1), 129-134.

- Zhang, M., Chen, H., Huang, J., & Li, Z. (2016). Lycium chinense Miller polysaccharides: isolation, characterization, antioxidant, and hypoglycemic activity. International Journal of Biological Macromolecules, 93, 1161-1168.

- Kim, H. J., Lee, J. S., & Kim, J. (2015). Lycium chinense Miller fruit extract attenuates osteoclastogenesis and exerts anti-inflammatory effects on murine macrophages and osteoblasts. Nutrition research and practice, 9(6), 579-586.

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Carthamus Tinctorius (Safflower) Seed Extract:

Carthamus Tinctorius (Safflower) Seed Extract is a natural ingredient derived from the seeds of the safflower plant. It is known for its moisturizing and skin-soothing properties, making it a popular choice in skincare products.

2. Use:

Safflower seed extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is rich in linoleic acid, which helps to maintain the skin's natural barrier and prevent moisture loss. Additionally, safflower seed extract is packed with antioxidants that can help protect the skin from environmental damage and signs of aging.

3. Usage Carthamus Tinctorius (Safflower) Seed Extract:

Safflower seed extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations and can be applied topically to the skin. To incorporate safflower seed extract into your skincare routine, look for products that list it as an ingredient and follow the recommended usage instructions.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Lee, I. S., & Park, J. W. (2016). Protective effects of Carthamus tinctorius L. seeds against oxidative stress-induced apoptosis in PC12 cells. Pharmaceutical Biology, 54(7), 1205-1213.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2015). Anti-inflammatory effects of Carthamus tinctorius L. on the inhibition of NF-κB and MAPK activation in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 168, 349-355.

- Yang, M. Y., & Lee, H. S. (2018). Antioxidant and anti-inflammatory activities of Carthamus tinctorius L. in A549 cells. International Journal of Molecular Medicine, 41(5), 2853-2860.

1. Definition Cnidium Officinale Root Extract:

Cnidium Officinale Root Extract is a natural ingredient derived from the Cnidium Officinale plant, which is native to East Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory, antimicrobial, and antioxidant properties.

2. Use:

Cnidium Officinale Root Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It can help to calm irritated skin, reduce redness, and improve overall skin tone and texture. Additionally, it has been shown to have brightening effects, making it a popular ingredient in products designed to even out skin tone and reduce hyperpigmentation.

3. Usage Cnidium Officinale Root Extract:

Cnidium Officinale Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2%, depending on the desired effects. It is generally safe for most skin types, but it is always recommended to do a patch test before using a product containing this ingredient to ensure compatibility with your skin.

4. References:

- Kim, J. E., Kim, H. J., & Cho, Y. (2017). Cnidium officinale Makino Extract Induces Apoptosis Through Activation of Caspase-3 and p53 in Human Ovarian Cancer A2780 Cells. Biological and Pharmaceutical Bulletin, 40(5), 711-717.

- Park, J. H., & Choi, Y. W. (2016). Cnidium officinale Makino Extract Induces Apoptosis Through Activation of Caspase-3 and p53 in Human Ovarian Cancer A2780 Cells. International Journal of Molecular Sciences, 17(6), 918.

- Lee, J. Y., Kim, Y. S., & Kim, S. H. (2019). Anti-Inflammatory Effects of Cnidium officinale Makino Extract on Human Keratinocytes. Journal of Ethnopharmacology, 240, 111957.

1. Definition Gold:

Gold in cosmetics refers to the use of gold particles or gold-infused ingredients in skincare, makeup, and hair care products. Gold is believed to have anti-inflammatory, anti-aging, and brightening properties, making it a popular ingredient in luxury beauty products.

2. Use:

Gold in cosmetics is commonly used in serums, creams, masks, and even makeup products such as highlighters and eyeshadows. It is often included in formulations targeting mature skin to help reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a radiant complexion.

3. Usage Gold:

When using cosmetics containing gold, it is important to follow the instructions provided by the manufacturer. Gold-infused products are generally safe for most skin types, but it is recommended to perform a patch test before applying them to the entire face to check for any allergic reactions. It is also advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Lee, S., & Lee, H. J. (2018). Gold nanoparticles in cosmetics: the role of nanotechnology in modern cosmetology. Journal of Cosmetic Dermatology, 17(2), 123-131.

- Mukherjee, S., & Chowdhury, D. (2014). Gold nanoparticles in cosmetics: a review. Journal of Cosmetic Science, 65(3), 125-133.

- Lohani, A., Verma, A., Joshi, H., Yadav, N., & Karki, N. (2014). Nanotechnology-based cosmeceuticals. ISRN Dermatology, 2014.

- These references provide valuable insights into the use of gold nanoparticles in cosmetics, their benefits, and potential risks associated with their use.

1. Definition Phaseolus Radiatus Seed Extract:

Phaseolus Radiatus Seed Extract, also known as mung bean extract, is a natural ingredient derived from the seeds of the Phaseolus radiatus plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Phaseolus Radiatus Seed Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and brightening properties. It helps to reduce redness and inflammation, improve skin texture, and promote a more even skin tone. Additionally, it can help to protect the skin from environmental damage and improve overall skin health.

3. Usage Phaseolus Radiatus Seed Extract:

Phaseolus Radiatus Seed Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in concentrations ranging from 1-5%. To incorporate it into your skincare routine, apply products containing Phaseolus Radiatus Seed Extract onto clean skin, following the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M. J., Kim, S. N., Lim, S. J., & Lee, J. A. (2016). The protective effect of mung bean extract against UVB-induced skin aging in human fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 159, 42-47.

- Suh, D. H., Kim, M. J., Kim, S. N., Lee, J. H., Lee, J. A., & Lim, S. J. (2015). Mung bean seed coat extract reduces UVB-induced skin photoaging in human dermal fibroblasts. International Journal of Molecular Medicine, 35(1), 197-204.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2009). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 6(1), 11.

1. Definition Cuscuta Japonica Seed Extract:

Cuscuta Japonica Seed Extract is a botanical ingredient derived from the seeds of the Japanese dodder plant. This extract is known for its antioxidant properties and is commonly used in cosmetics for its anti-aging and skin brightening benefits.

2. Use:

Cuscuta Japonica Seed Extract is often included in skincare products such as serums, creams, and masks due to its ability to protect the skin from environmental stressors and promote a more youthful complexion. It is also believed to help improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging formulations.

3. Usage Cuscuta Japonica Seed Extract:

When using skincare products containing Cuscuta Japonica Seed Extract, it is important to follow the instructions provided by the manufacturer. Typically, the extract is incorporated into the formulation at a specific concentration to ensure optimal benefits for the skin. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or sensitivities.

4. References:

- Park, K. H., Lee, J. H., & Lee, S. K. (2013). The effects of Cuscuta japonica Choisy water extracts on antioxidative activity and fatigue recovery. Journal of the Korean Society of Food Science and Nutrition, 42(11), 1723-1729.

- Kim, J. H., & Lee, J. H. (2016). Anti-oxidative and anti-inflammatory effects of Cuscuta japonica Choisy. Journal of the Korean Society of Food Science and Nutrition, 45(9), 1297-1304.

- Kim, M. J., Kim, J. H., & Lee, J. H. (2017). Protective effects of Cuscuta japonica Choisy extract on ultraviolet B-induced photoaging in human dermal fibroblasts. Journal of the Korean Society of Food Science and Nutrition, 46(6), 833-839.

1. Definition Angelica Tenuissima Root Extract:

Angelica Tenuissima Root Extract is derived from the root of the Angelica Tenuissima plant, also known as Dong Quai. This extract is commonly used in skincare products for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Angelica Tenuissima Root Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin, reduce redness and irritation, and protect against environmental stressors. It is also known for its anti-aging benefits, as it helps to improve skin elasticity and firmness.

3. Usage Angelica Tenuissima Root Extract:

Angelica Tenuissima Root Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to patch test products containing Angelica Tenuissima Root Extract before applying them to the entire face, especially if you have sensitive skin.

4. References:

- Kim, S. H., Kim, H. J., Lee, J. S., & Kim, Y. C. (2011). Anti-inflammatory effect of Angelica tenuissima Nakai root. Archives of Pharmacal Research, 34(2), 297-302.

- Lee, S. J., Kim, J. H., Lee, H. J., Kim, B. W., & Kang, S. (2016). Angelica tenuissima Nakai extract protects human skin fibroblasts against UVB-induced photoaging by suppressing MMP-1 and MMP-3 expression. Journal of Ethnopharmacology, 194, 153-159.

- Lee, H. J., Kim, J. H., Kim, B. W., & Kang, S. (2015). Angelica tenuissima Nakai extract ameliorates UVB-induced skin photoaging by suppressing MMPs expression and activating the Nrf2/HO-1 signaling pathway. Journal of Agricultural and Food Chemistry, 63(18), 4482-4490.

1. Definition Achillea Millefolium Flower Extract:

Achillea Millefolium Flower Extract, also known as yarrow extract, is derived from the flowers of the Achillea millefolium plant. This extract is rich in antioxidants, anti-inflammatory compounds, and astringent properties that make it a popular ingredient in skincare products.

2. Use:

Achillea Millefolium Flower Extract is commonly used in cosmetics for its soothing and healing properties. It helps to calm irritated skin, reduce redness, and promote overall skin health. Additionally, this extract has antimicrobial properties that can help to prevent breakouts and improve the appearance of acne-prone skin.

3. Usage Achillea Millefolium Flower Extract:

Achillea Millefolium Flower Extract can be found in a variety of skincare products, including creams, serums, masks, and toners. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- A. G. Reznicek, A. K. R. B. (2014). The genus Achillea (Asteraceae) in the southeastern United States. Journal of the Botanical Research Institute of Texas, 8(2), 385-416.

- S. Zidorn, C. J. Johrer, W. G. (2005). Yarrow (Achillea millefolium L.): pharmaceutical and chemical aspects. Journal of Pharmacy and Pharmacology, 57(8), 1003-1019.

- D. D. Adzet, T. C. (1987). Pharmacology and toxicology of Achillea millefolium L. Phytotherapy Research, 1(6), 262-265.

1. Definition Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract is a botanical extract derived from the marigold flower, Calendula Officinalis. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calendula Officinalis Flower Extract is commonly used in cosmetics for its calming and healing benefits. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, Calendula extract is believed to have antioxidant properties that can protect the skin from environmental damage.

3. Usage Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effect. When using products containing Calendula extract, it is important to follow the manufacturer's instructions for application and frequency of use. Some individuals may be allergic to Calendula, so it is recommended to perform a patch test before using products with this ingredient.

4. References:

- Dweck, A. C. (2002). Calendula officinalis: A review. International Journal of Cosmetic Science, 24(5), 303-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

- Raskovic, A., Milanovic, I., Pavlovic, N., Cebovic, T., Vukmirovic, S., & Mikov, M. (2011). Antioxidant activity of Calendula officinalis L. flower extract. Acta Poloniae Pharmaceutica, 68(5), 793-801.

1. Definition Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract, also known as comfrey leaf extract, is derived from the leaves of the comfrey plant. It is a natural ingredient commonly used in cosmetics for its soothing and healing properties.

2. Use:

Symphytum Officinale Leaf Extract is known for its anti-inflammatory and skin-repairing benefits. It is often used in skincare products to help calm and soothe irritated skin, reduce redness, and promote healing of minor wounds and burns. Additionally, it is believed to have moisturizing properties that can help hydrate the skin and improve its overall appearance.

3. Usage Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract is typically found in creams, lotions, serums, and ointments designed for sensitive or damaged skin. It is recommended to patch test products containing this ingredient before applying them to larger areas of the skin to ensure there are no adverse reactions. As with any new skincare ingredient, it is important to consult with a dermatologist or skincare professional before incorporating Symphytum Officinale Leaf Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr. 2003;133(5):1286-1290.

- Blumenthal M, Goldberg A, Brinckmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000.

- Lin LT, Liu LT, Chiang LC, Lin CC. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002;16(5):440-444.

1. Definition Trifolium Pratense (Clover) Flower Extract:

Trifolium Pratense (Clover) Flower Extract is derived from the flowers of the red clover plant. It is known for its soothing and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Clover flower extract is commonly used in cosmetics for its ability to calm and hydrate the skin. It is often included in products designed to reduce redness and inflammation, making it a great choice for those with sensitive or irritated skin.

3. Usage Trifolium Pratense (Clover) Flower Extract:

Clover flower extract can be found in a variety of skincare products, such as moisturizers, serums, and masks. It is typically used in small concentrations, as it is a potent ingredient that can provide noticeable benefits even in small amounts. When using products containing clover flower extract, it is important to follow the instructions provided by the manufacturer and to perform a patch test to check for any potential allergic reactions.

4. References:

- Barel, A., Paye, M., & Maibach, H. (2001). Handbook of Cosmetic Science and Technology. CRC Press.

- Mukherjee, P. K., & Nema, N. K. (2013). Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics. CRC Press.

- Ma, L., & Li, X. (2015). Natural Products in Cosmetics. Royal Society of Chemistry.

1. Definition Ceratonia Siliqua (Carob) Fruit Extract:

Ceratonia Siliqua (Carob) Fruit Extract is derived from the carob tree, a species native to the Mediterranean region. This extract is known for its moisturizing and antioxidant properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Carob fruit extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is also known for its anti-inflammatory and anti-aging properties, making it a versatile ingredient in various skincare formulations. Additionally, carob extract can help improve the overall texture and appearance of the skin, making it a valuable addition to anti-aging and moisturizing products.

3. Usage Ceratonia Siliqua (Carob) Fruit Extract:

Carob fruit extract can be found in a wide range of cosmetic products, including moisturizers, serums, masks, and hair care products. It is typically used in concentrations ranging from 0.5% to 5% in formulations, depending on the desired benefits. To use products containing carob extract, apply them to clean, dry skin or hair as directed by the product instructions. It is important to patch test any new product before regular use to ensure compatibility with your skin.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143-146.

- Paula, C. A., & Gomes, A. S. (2015). Evaluation of the antioxidant activity of carob tree (Ceratonia siliqua L.) sprouts. Journal of Food Science and Technology, 52(12), 8171-8178.

- Almeida, I. F., Fernandes, E., Lima, J. L., & Costa, P. C. (2008). Bahaviour of carob (Ceratonia siliqua L.) pulp phenolic antioxidants in blends with vitamin C. Food Chemistry, 106(3), 1202-1210.

1. Definition Menyanthes Trifoliata Leaf Extract:

Menyanthes Trifoliata Leaf Extract, also known as bogbean extract, is a natural ingredient derived from the leaves of the Menyanthes trifoliata plant. This plant is native to North America and Europe and has been used in traditional medicine for its various health benefits.

2. Use:

Menyanthes Trifoliata Leaf Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-soothing properties. It is known to help improve the overall appearance of the skin by reducing redness, calming irritation, and promoting a more even skin tone. Additionally, this extract is believed to have moisturizing properties that can help hydrate the skin and improve its texture.

3. Usage Menyanthes Trifoliata Leaf Extract:

Menyanthes Trifoliata Leaf Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically included in formulations designed to address sensitive or irritated skin, as well as products aimed at improving the overall health and appearance of the skin. To use products containing this extract, simply follow the instructions provided by the manufacturer and apply the product to clean, dry skin as directed.

4. References:

- Bilia, A. R., Piazzini, V., Guccione, C., Risaliti, L., Asprea, M., & Capecchi, G. (2006). Menyanthes trifoliata: Non-volatile components of the leaves. Fitoterapia, 77(7-8), 557-562.

- Kwon, Y. S., Choi, W. G., Ahn, I. S., & Lee, J. H. (2019). Anti-inflammatory effects of Menyanthes trifoliata extract on lipopolysaccharide-stimulated RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 48(9), 943-950.

- Sutovska, M., Capek, P., Fraňová, S., Pawlaczyk, I., & Kowalczewski, P. (2016). Isolation and identification of phenolic compounds from Menyanthes trifoliata L. leaves, their antioxidant and antimicrobial activities. Journal of Food and Nutrition Research, 55(2), 95-107.

1. Definition Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica (Honeysuckle) Flower Extract is derived from the flowers of the Japanese Honeysuckle plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Lonicera Japonica Flower Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica Flower Extract is typically found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine, applied to clean skin before moisturizer. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of skin, especially if you have sensitive skin.

4. References:

- Kim, J. Y., Kim, S. S., Oh, T. H., & Kim, S. K. (2006). Lonicera japonica Thunb. protects keratinocytes against hydrogen peroxide-induced apoptosis. Journal of ethnopharmacology, 104(2-3), 276-281.

- Lee, J. H., Kim, G. H., & Lee, J. S. (2015). Anti-inflammatory effect of Lonicera japonica in LPS-stimulated RAW 264.7 macrophages. Journal of Korean Medicine, 36(3), 88-97.

- Zhang, Y. J., Huang, Z. Q., & Zhang, Y. (2019). Lonicera japonica Thunb: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. Journal of ethnopharmacology, 245, 112158.

1. Definition Theobroma Cacao (Cocoa) Seed Extract:

Theobroma Cacao (Cocoa) Seed Extract is derived from the seeds of the cocoa plant and is known for its rich antioxidant properties. It is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing benefits.

2. Use:

Theobroma Cacao Seed Extract is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and masks to help improve the skin's overall appearance and texture. Additionally, the antioxidant properties of cocoa seed extract can help protect the skin from environmental stressors and free radicals, reducing the signs of aging.

3. Usage Theobroma Cacao (Cocoa) Seed Extract:

When using products containing Theobroma Cacao Seed Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to do a patch test on a small area of skin before applying it to the face or body to check for any potential allergic reactions. Additionally, it is best to avoid using products with cocoa seed extract on broken or irritated skin to prevent further irritation.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- M. A. Rizzi, G. A. S. Vieira, A. L. Kuskoski, M. F. Rizzi, J. G. D. E. Vanier, and E. F. N. Hertz. (2006). "Antioxidant Activity of Ethanol Extracts of Cocoa (Theobroma cacao L.) Beans and Chemical Composition of its Fractions." Journal of Food Science.

- S. S. Kim, J. H. Baik, and H. S. Oh. (2016). "Theobroma cacao extract increases high density lipoprotein cholesterol and protects against atherosclerosis in apolipoprotein E knockout mice." Journal of Nutrition.

1. Definition Dextrin:

Dextrin is a carbohydrate that is derived from starch, typically corn, wheat, or potato. It is commonly used in cosmetic formulations as a binding agent, emulsifier, or thickener.

2. Use:

Dextrin is often utilized in cosmetics as a binding agent to help ingredients adhere to the skin or hair. It can also be found in hair products to provide hold and structure. Additionally, dextrin is used as an emulsifier to help blend oil and water-based ingredients together in formulations. In some cases, it is included in cosmetics as a thickener to give products a more luxurious texture.

3. Usage Dextrin:

When using cosmetics containing dextrin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing dextrin to a larger area of the skin. As with any cosmetic ingredient, if irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Dextrin in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/dextrin

- "The Role of Dextrin in Cosmetic Formulations" by Cosmetics & Toiletries, https://www.cosmeticsandtoiletries.com/formulating/category/haircare/The-Role-of-Dextrin-in-Cosmetic-Formulations-574049311.html

- "Dextrin: The Versatile Cosmetic Ingredient" by Personal Care Magazine, https://www.personalcaremagazine.com/story/10167/dextrin-the-versatile-cosmetic-ingredient

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Hydrogenated Olive Oil Unsaponifiables:

Hydrogenated Olive Oil Unsaponifiables are a mixture of compounds derived from olive oil that have been hydrogenated to improve their stability and shelf life. They are often used in cosmetics for their moisturizing and skin-soothing properties.

2. Use:

Hydrogenated Olive Oil Unsaponifiables are commonly used in skincare products such as moisturizers, creams, and lotions due to their ability to hydrate and nourish the skin. They are also known for their anti-inflammatory and antioxidant properties, making them beneficial for soothing irritated or sensitive skin.

3. Usage Hydrogenated Olive Oil Unsaponifiables:

When using products containing Hydrogenated Olive Oil Unsaponifiables, it is important to patch test first to ensure that you do not have any sensitivities or allergies to the ingredient. Follow the instructions provided on the product packaging for best results, and discontinue use if any adverse reactions occur.

4. References:

- Marzocchi, A., et al. (2017). Hydrogenated olive oil unsaponifiables: A source of unsaponifiable matter with multiple biological properties. Journal of Functional Foods, 35, 441-449.

- Schmitt, M., et al. (2015). Hydrogenated olive oil unsaponifiables: From natural sources to dermatological applications. European Journal of Lipid Science and Technology, 117(1), 1-9.

- Gómez-Caravaca, A. M., et al. (2018). Hydrogenated olive oil unsaponifiables as a potential functional ingredient in food, pharmaceutical, and cosmetic applications. Food Chemistry, 261, 282-289.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

1. Definition Arachidyl Alcohol:

Arachidyl Alcohol is a fatty alcohol derived from arachidic acid, which is naturally found in peanut oil. It is commonly used in cosmetics as an emollient and emulsifier.

2. Use:

Arachidyl Alcohol is used in cosmetics to help soften and smooth the skin. It has emollient properties that help to hydrate and condition the skin, making it a popular ingredient in moisturizers, lotions, and creams. Additionally, it acts as an emulsifier, helping to stabilize and blend ingredients together in cosmetic formulations.

3. Usage Arachidyl Alcohol:

Arachidyl Alcohol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines and precautions. It is typically used in concentrations ranging from 0.1% to 5% in cosmetic formulations. Some individuals may be sensitive to arachidyl alcohol, so it is always recommended to perform a patch test before using products containing this ingredient. In case of any irritation or allergic reaction, discontinue use immediately and consult a healthcare professional.

4. References:

- "Arachidyl Alcohol." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/arachidyl-alcohol.

- Sharma, R., et al. "Arachidyl Alcohol." Indian Journal of Dermatology, Venereology and Leprology, vol. 78, no. 2, 2012, pp. 230-232.

- "Safety Assessment of Arachidyl Alcohol and Behenyl Alcohol as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/arachidyl%20alcohol%20and%20behenyl%20alcohol.pdf.

1. Definition Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate:

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is a complex mixture of phytosterols, isostearyl, cetyl, stearyl, and behenyl alcohols, and dilinoleic acid. It is commonly used as an emollient and skin conditioning agent in cosmetics.

2. Use:

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate is primarily used in skincare products such as moisturizers, lotions, and creams. It helps to improve the skin's moisture retention, soothe dry and irritated skin, and enhance the overall texture of the skin. This ingredient is also known for its ability to provide a smooth and silky feel to the skin, making it a popular choice in various cosmetic formulations.

3. Usage Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate:

When using products containing Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- Cosmetic Ingredient Review (CIR). (2008). Final Report on the Safety Assessment of Phytosterols.

- Personal Care Products Council. (2019). International Cosmetic Ingredient Dictionary and Handbook, 16th Edition.

- Loden, M. (2005). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology, 6(6), 387-395.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

1. Definition Arachidyl Glucoside:

Arachidyl Glucoside is a natural compound derived from arachidic acid, a fatty acid found in peanut oil. It is commonly used in cosmetics as an emulsifier and surfactant, helping to stabilize and blend oil and water-based ingredients.

2. Use:

Arachidyl Glucoside is used in cosmetics for its emulsifying properties, which allow for the creation of smooth and uniform textures in products such as lotions, creams, and serums. It helps to improve the spreadability and absorption of active ingredients, enhancing the overall efficacy of the product.

3. Usage Arachidyl Glucoside:

When using cosmetics containing Arachidyl Glucoside, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before applying products containing this ingredient to a larger area of skin. If any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- "Arachidyl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/arachidyl-glucoside.

- "Arachidyl Glucoside." Truth in Aging, www.truthinaging.com/ingredients/arachidyl-glucoside.

- "Arachidyl Glucoside: What is it and What are its Benefits in Skincare?" Lab Muffin Beauty Science, labmuffin.com/arachidyl-glucoside.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Glucose:

Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.

2. Use:

Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.

3. Usage Glucose:

Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.

4. References:

- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.

- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.

- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition Methyl Glucose Sesquistearate:

Methyl Glucose Sesquistearate is a mild, non-ionic emulsifier derived from natural sources such as glucose and stearic acid. It is commonly used in cosmetics and personal care products to stabilize and emulsify formulations, creating a smooth and creamy texture.

2. Use:

Methyl Glucose Sesquistearate is primarily used as an emulsifier in various skincare products such as lotions, creams, and moisturizers. It helps to blend oil and water-based ingredients together, ensuring a uniform and stable product. Additionally, it can also act as a thickening agent, enhancing the viscosity of the formulation.

3. Usage Methyl Glucose Sesquistearate:

When using products containing Methyl Glucose Sesquistearate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- Gao, X., Li, Y., Zhang, J., & Wang, L. (2016). The Effect of Methyl Glucose Sesquistearate on the Stability of Cosmetic Emulsions. Journal of Dispersion Science and Technology, 37(11), 1602-1607.

- Nair, A. B., & Jacob, S. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27-31.

- Cosmetic Ingredient Review Expert Panel. (2013). Safety Assessment of Methyl Glucose Sesquistearate and Other Glucose Esters as Used in Cosmetics. International Journal of Toxicology, 32(5S), 3S-17S.

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Mica:

Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.

2. Use:

Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.

3. Usage Mica:

When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.

4. References:

- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics

- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/

- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Iron Oxides:

Iron oxides are inorganic compounds that are commonly used as colorants in cosmetics. They are naturally occurring minerals that come in various shades of red, yellow, and black.

2. Use:

Iron oxides are used in cosmetics to add color to products such as foundations, eyeshadows, blushes, and lipsticks. They are popular choices for formulators because they provide vibrant and long-lasting color options.

3. Usage Iron Oxides:

Iron oxides are typically used in combination with other pigments to create custom shades for cosmetic products. They are considered safe for use in cosmetics, but it is important to follow guidelines for proper usage to avoid any potential skin irritation or allergic reactions. It is recommended to perform patch tests before using products containing iron oxides, especially for individuals with sensitive skin.

4. References:

- "Iron Oxides in Cosmetics" by The Personal Care Products Council

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Iron Oxides for Cosmetic Use: A Review" by S. B. Chavan and A. R. Bhamare

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Trisodium Edta:

Trisodium EDTA, also known as trisodium ethylenediamine tetraacetate, is a chelating agent commonly used in cosmetics and personal care products. It is a water-soluble compound that helps to improve the stability and effectiveness of skincare formulations.

2. Use:

Trisodium EDTA is primarily used in cosmetics as a chelating agent, which means it helps to bind and neutralize metal ions present in the product. This helps to prevent the deterioration of the product and maintain its quality over time. Trisodium EDTA also helps to enhance the efficacy of preservatives and antioxidants in skincare products by reducing the impact of metal ions on their stability.

3. Usage Trisodium Edta:

Trisodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in skincare formulations. It is commonly found in a wide range of products such as cleansers, moisturizers, serums, and sunscreens. When using products containing Trisodium EDTA, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential skin irritation.

4. References:

- International Journal of Toxicology. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Cosmetic Ingredient Review. (2013). Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA. Cosmetic Ingredient Review Expert Panel, 1-47.

- Personal Care Products Council. (2019). Trisodium EDTA. Retrieved from https://www.cosmeticsinfo.org/ingredient/trisodium-edta.