Name: Topix Replenix Gly-Sal 5-2 Pads
Brand: Topix
Rating: 5 (6 reviews)

Salicylic Acid

Other Names: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

Mineral Water

1. Definition Mineral Water:

Mineral water in cosmetics refers to water sourced from natural mineral springs that contains various minerals and trace elements beneficial for the skin.

2. Use:

Mineral water is commonly used in cosmetics as a hydrating and refreshing ingredient. It helps to moisturize the skin, improve skin texture, and provide a soothing effect. Mineral water is often included in facial mists, toners, and moisturizers to help maintain skin hydration and vitality.

3. Usage Mineral Water:

Mineral water can be used in various ways in skincare routines. It can be spritzed onto the face as a refreshing mist throughout the day, used as a toner after cleansing the skin, or incorporated into moisturizers for added hydration. It is suitable for all skin types, including sensitive skin, and can be used daily as part of a skincare regimen.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2012). Dry skin and moisturizers: chemistry and function. CRC Press.

Glycolic Acid

Other Names: Hydroxyacetic acid

Function: pH adjusting agent, pH adjusting agent, Exfoliant

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

Sd40 Alcohol (13& V/V)

Ingredient data is being updated. Please check back later.

Witch Hazel

Other Names: hamamelis; hamanelis; hamamelis virginiana; Witch Hazel

1. Definition Hamamelis Virginiana (Witch Hazel):

Hamamelis Virginiana, commonly known as Witch Hazel, is a plant native to North America that has been used for centuries for its medicinal properties. Witch Hazel extract is derived from the leaves and bark of the plant and is known for its astringent, anti-inflammatory, and antioxidant properties.

2. Use:

Witch Hazel is commonly used in cosmetics for its ability to tighten and tone the skin, reduce inflammation, and minimize the appearance of pores. It is often found in toners, cleansers, and moisturizers for its soothing and clarifying effects on the skin. Witch Hazel is also used in hair care products to help balance oil production and promote a healthy scalp.

3. Usage Hamamelis Virginiana (Witch Hazel):

Witch Hazel can be applied topically to the skin using a cotton pad or as an ingredient in skincare products. It is generally safe for most skin types, but it is recommended to do a patch test before using it on the face or body to check for any allergic reactions. Witch Hazel should not be ingested and should be kept out of reach of children.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine: The Definitive Home Reference Guide to 550 Key Herbs with all their Uses as Remedies for Common Ailments. DK Publishing, 2016.

- Duke, James A., and Mary Jo Bogenschutz-Godwin. Handbook of Medicinal Herbs, Second Edition. CRC Press, 2002.

- Reuter, J., et al. "Investigations on the anti-inflammatory activity of a herbal drug combination of stinging nettle herb, couch grass root and witch hazel leaves." Phytomedicine 10.8 (2003): 700-708.

Ammonium Hydroxide

Function: pH adjusting agent, pH adjusting agent, Denaturant

1. Definition Ammonium Hydroxide:

Ammonium hydroxide, also known as ammonia solution, is a colorless liquid chemical compound composed of ammonia and water. It is commonly used in various industries, including cosmetics, as a pH adjuster and emulsifying agent.

2. Use:

In cosmetics, ammonium hydroxide is primarily used as a pH adjuster to help maintain the desired acidity or alkalinity of a product. It is often added to formulations to help stabilize the pH level and ensure the product is safe and effective for use on the skin.

3. Usage Ammonium Hydroxide:

When using cosmetics containing ammonium hydroxide, it is important to follow the manufacturer's instructions carefully. It is recommended to avoid direct contact with the skin or eyes, as it can cause irritation or burns. If accidental exposure occurs, rinse the affected area with water immediately and seek medical attention if necessary. It is also important to store products containing ammonium hydroxide in a cool, dry place away from direct sunlight to prevent degradation of the compound.

4. References:

- "Ammonium Hydroxide." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/ammonium-hydroxide.

- "Ammonium Hydroxide." Personal Care Council, www.personalcarecouncil.org/ingredient-ammonium-hydroxide/.

- "Ammonium Hydroxide." Environmental Working Group, www.ewg.org/skindeep/ingredients/702159-AMMONIUM_HYDROXIDE/.

Polysorbate 20

Other Names: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Disodium Edta

Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Sodium Benzoate

Other Names: natri benzoat

Function: Masking, Fragrance, Preservative, Anticorrosive

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

Acetone

Other Names: Axetol

Function: Solvent, Fragrance, Denaturant

1. Definition Acetone:

Acetone is a colorless, volatile liquid solvent that is commonly used in cosmetics as a nail polish remover. It is also known as propanone and is a key ingredient in many personal care products.

2. Use:

Acetone is primarily used in cosmetics as a solvent to dissolve other substances, such as nail polish. It is highly effective at removing nail polish quickly and efficiently, making it a popular choice for consumers looking to change their nail color. Acetone is also used in some skincare products as a degreasing agent to remove oils and fats from the skin.

3. Usage Acetone:

When using acetone in cosmetics, it is important to take precautions to avoid skin irritation or other adverse effects. It is recommended to use acetone in a well-ventilated area to prevent inhalation of fumes. Additionally, it is important to avoid contact with the eyes and skin, as acetone can cause irritation and dryness. It is also recommended to wash hands thoroughly after using acetone to remove any residue.

4. References:

- "Acetone in Cosmetics: Safety and Regulatory Considerations" by J. J. Scrafford and M. A. Maronpot

- "The Role of Acetone in Cosmetics and Personal Care Products" by M. A. Kline

- "Acetone: A Versatile Solvent in Cosmetics" by S. M. Smith

Imidazolidinyl Urea

Other Names: Germall 115; Imidurea

Function: Preservative

1. Definition Imidazolidinyl Urea:

Imidazolidinyl Urea is a synthetic preservative that is commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde, which acts as a preservative.

2. Use:

Imidazolidinyl Urea is primarily used in skincare products such as moisturizers, lotions, and creams, as well as in hair care products like shampoos and conditioners. It is also found in makeup products like foundations and mascaras. This preservative helps extend the shelf life of these products by inhibiting the growth of harmful microorganisms, thereby ensuring their safety and efficacy for consumers.

3. Usage Imidazolidinyl Urea:

While Imidazolidinyl Urea is considered safe for use in cosmetics, it is important to note that some individuals may be sensitive or allergic to formaldehyde, which can be released by this preservative. Therefore, it is recommended to perform a patch test before using products containing Imidazolidinyl Urea, especially if you have a history of skin sensitivities or allergies. Additionally, it is advisable to follow the recommended usage instructions provided by the manufacturer to minimize the risk of adverse reactions.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Imidazolidinyl Urea. International Journal of Toxicology. 1996;15(Suppl 1):123-141.

- Personal Care Products Council. Imidazolidinyl Urea. Accessed from: https://www.cosmeticsinfo.org/ingredient/imidazolidinyl-urea

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. Accessed from: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.19

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1	-	Mineral Water
1 4	B	Glycolic Acid (pH adjusting agent, pH adjusting agent, Exfoliant)	Anti Aging Bad for sensitive skin Good for oily skin
-	-	Sd40 Alcohol (13& V/V)
1	-	Witch Hazel
2 3	-	Ammonium Hydroxide (pH adjusting agent, pH adjusting agent, Denaturant )
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger Cleansing
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 3	A	Sodium Benzoate (Masking, Fragrance, Preservative, Anticorrosive)
3	-	Acetone (Solvent, Fragrance, Denaturant )	Bad for sensitive skin
6	A	Imidazolidinyl Urea (Preservative)

Topix Replenix Gly-Sal 5-2 Pads

Ingredients

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Ingredient List