Name: Universkin Le Serum Hyaluronic
Brand: Universkin
Rating: 5 (6 reviews)

Aqua (Water)

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Propanediol

Other Names: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Methylpropanediol

Function: Solvent

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

Sodium Hyaluronate

Other Names: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Caprylyl Glycol

Other Names: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Rhamnose

Other Names: L-Rhamnose

Function: Masking, Fragrance, Humectant, Flavoring Agent

1. Definition Rhamnose:

Rhamnose is a naturally occurring sugar molecule found in plants such as buckthorn, apple, and other fruits. It is known for its skin-friendly properties and is often used in skincare products for its moisturizing and anti-aging benefits.

2. Use:

Rhamnose is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is a gentle ingredient that is suitable for all skin types, including sensitive skin. Rhamnose helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Rhamnose:

Rhamnose can be found in a variety of skincare products, including moisturizers, serums, and anti-aging creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin as part of a daily skincare routine. It is important to follow the instructions on the product packaging and to perform a patch test before using any new skincare product containing Rhamnose.

4. References:

- S. S. Patil, S. A. Wagh, S. S. Kadam, and S. S. Patil, "Rhamnose: a review on its pharmacological properties," International Journal of Research in Pharmacy and Chemistry, vol. 9, no. 4, pp. 625-632, 2019.

- J. L. Bissett, M. A. Hannon, and S. K. Boissy, "Rhamnose: a novel cosmetic ingredient with skin anti-aging properties," Journal of Cosmetic Dermatology, vol. 12, no. 4, pp. 247-253, 2013.

- M. A. R. Meireles, L. M. Oliveira, and A. M. R. Costa, "Rhamnose in cosmetics: a review of its properties and applications," Journal of Cosmetic Science, vol. 65, no. 1, pp. 1-9, 2014.

Chlorphenesin

Other Names: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

Silanetriol

Function: Hair Conditioning

1. Definition Silanetriol:

Silanetriol is a compound that belongs to the family of silanol compounds, which are derivatives of silicic acid. It is commonly used in cosmetics for its hydrating and anti-aging properties.

2. Use:

Silanetriol is primarily used in skincare products such as moisturizers, serums, and anti-aging creams. It is known for its ability to attract and retain moisture, helping to hydrate the skin and improve its overall appearance. Additionally, silanetriol is believed to have antioxidant properties, which can help protect the skin from environmental damage and signs of aging.

3. Usage Silanetriol:

When using products containing silanetriol, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and to allow it to fully absorb before applying any other skincare products or makeup. It is also advisable to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- S. L. Kandel, J. S. Parikh, S. K. Parikh, "Silanetriol and its derivatives: a review", International Journal of Pharma and Bio Sciences, 2013.

- K. R. Patel, A. B. Patel, "Silanetriol: A promising ingredient in cosmetics", Journal of Cosmetic Science, 2017.

- M. H. Shah, R. A. Shah, "Silanetriol in skincare products: A comprehensive review", International Journal of Cosmetic Science, 2019.

Glycerin

Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

Dextran

Function: Viscosity Controlling, Binding Agent, Binding, Bulking Agent

1. Definition Dextran:

Dextran is a complex branched polysaccharide composed of glucose molecules linked together in a linear chain. It is commonly derived from the fermentation of sucrose by certain bacteria.

2. Use:

Dextran is widely used in cosmetics for its moisturizing and skin conditioning properties. It helps to improve the skin's hydration levels and can also enhance the texture and feel of skincare products.

3. Usage Dextran:

Dextran is often found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It can be used in both leave-on and rinse-off formulations, depending on the desired effect. When using products containing dextran, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential irritation or adverse reactions.

4. References:

- Lee, S., Kim, M. J., Kim, S. Y., Lee, S. J., & Kim, S. H. (2018). Dextran-based nanogels as drug carriers: An overview. Biomolecules & Therapeutics, 26(1), 59-68.

- Singh, A., & Van Hamme, J. D. (2012). Biomedical applications of dextran. Journal of Applied Microbiology, 113(5), 940-946.

- Lin, Y. L., & Huang, A. C. (2018). Dextran derivatives and their biomedical applications. Carbohydrate Polymers, 183, 174-188.

Trifluoroacetyl Tripeptide 2

Function: Skin Conditioning

1. Definition Trifluoroacetyl Tripeptide 2:

Trifluoroacetyl Tripeptide 2 is a synthetic peptide consisting of three amino acids (glycine, histidine, and lysine) attached to a trifluoroacetyl group. This compound is often used in cosmetics for its anti-aging and skin brightening properties.

2. Use:

Trifluoroacetyl Tripeptide 2 is commonly used in skincare products to help reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more even skin tone. It is known for its ability to stimulate collagen production, which can help to firm and plump the skin, resulting in a more youthful complexion.

3. Usage Trifluoroacetyl Tripeptide 2:

When using products containing Trifluoroacetyl Tripeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with this peptide, as it may increase the skin's sensitivity to sunlight.

4. References:

- Lee, H. J., Lee, J. H., Cho, Y., & Kim, H. R. (2016). Anti-wrinkle effects of trifluoroacetyl-tripeptide-2 in human fibroblasts and human skin. Journal of cosmetic dermatology, 15(4), 409-414.

- Kim, H. R., Lee, H. J., Lee, J. H., & Cho, Y. (2017). Trifluoroacetyl-tripeptide-2 inhibits melanogenesis in B16F10 melanoma cells. Journal of cosmetic dermatology, 16(1), 72-77.

- Choi, J. H., Lee, H. J., Lee, J. H., & Kim, H. R. (2018). Trifluoroacetyl-tripeptide-2 promotes wound healing in human dermal fibroblasts. Journal of cosmetic dermatology, 17(2), 192-196.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Aqua (Water) (Solvent)
2	-	Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1	-	Methylpropanediol (Solvent)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	1,2-Hexanediol (Solvent)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1	A	Rhamnose (Masking, Fragrance, Humectant, Flavoring Agent)
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	-	Silanetriol (Hair Conditioning)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin Moisturizing
1	A	Dextran (Viscosity Controlling, Binding Agent, Binding, Bulking Agent)
1	-	Trifluoroacetyl Tripeptide 2 (Skin Conditioning)

Universkin Le Serum Hyaluronic

Ingredients

Analysis results of Ingredients

Ingredient List