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1. Definition Mica:

Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.

2. Use:

Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.

3. Usage Mica:

When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.

4. References:

- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics

- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/

- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Trimethylsiloxysilicate:

Trimethylsiloxysilicate is a silicone-based ingredient commonly used in cosmetics as a film-forming agent and binder. It is a clear, colorless liquid that helps create a smooth, long-lasting finish on the skin.

2. Use:

Trimethylsiloxysilicate is primarily used in cosmetics to improve the staying power of makeup products such as foundations, eyeliners, and lipsticks. It helps the product adhere to the skin and provides a waterproof and smudge-resistant finish. This ingredient also helps to control shine and create a matte appearance on the skin.

3. Usage Trimethylsiloxysilicate:

Trimethylsiloxysilicate is generally considered safe for use in cosmetics, but some precautions should be taken when using products containing this ingredient. It is important to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, it is recommended to perform a patch test before using a product with Trimethylsiloxysilicate, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2011). Final report on the safety assessment of trimethylsiloxysilicate. International Journal of Toxicology, 30(2 Suppl), 95S-110S.

- Personal Care Products Council. (n.d.). Trimethylsiloxysilicate. Retrieved from https://www.cosmeticsinfo.org/ingredient/trimethylsiloxysilicate

- Luebberding, S., & Krueger, N. (2013). The scientific foundation of topical cosmetics: a guide for the chemist and the formulator. Springer Science & Business Media.

1. Definition Triethoxycaprylylsilane:

Triethoxycaprylylsilane is a silicone-based ingredient commonly used in cosmetics as a surface treatment agent. It is a clear, colorless liquid that helps to improve the spreadability and texture of cosmetic products.

2. Use:

Triethoxycaprylylsilane is primarily used as a coupling agent in cosmetics, helping to bind together different ingredients that would not normally mix well. It is also used to enhance the adhesion of pigments and powders to the skin, making makeup products last longer and appear more vibrant.

3. Usage Triethoxycaprylylsilane:

Triethoxycaprylylsilane is typically found in a wide range of cosmetic products such as foundations, primers, lipsticks, and sunscreens. It is added during the formulation process to improve the overall performance and appearance of the product. When using cosmetics containing Triethoxycaprylylsilane, it is important to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- "Safety Assessment of Triethoxycaprylylsilane as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2018)

- "Silanes and Other Coupling Agents, Volume 3" by George Wypych (2016)

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach (2001)

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

1. Definition Diisostearyl Malate:

Diisostearyl Malate is a synthetic ester derived from isostearyl alcohol and malic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Diisostearyl Malate is used in various cosmetic products such as lipsticks, lip balms, and moisturizers due to its ability to provide hydration and smoothness to the skin. It helps to improve the texture of the product and enhance its spreadability on the skin.

3. Usage Diisostearyl Malate:

Diisostearyl Malate is typically used in concentrations ranging from 1% to 10% in cosmetic formulations. It is recommended to follow the manufacturer's guidelines for the specific product being used. Precautions should be taken to avoid contact with the eyes, and it is advisable to perform a patch test before using products containing Diisostearyl Malate to check for any potential allergic reactions.

4. References:

- Yang, F., Liu, Y., Liu, Y., & Li, L. (2018). Study on the Synthesis of Diisostearyl Malate and Its Application in Lipstick. Journal of Oleo Science, 67(12), 1593-1601.

- Kim, J., Kim, H., & Kim, S. (2017). Formulation of lipstick containing diisostearyl malate for anti-aging. Journal of the Society of Cosmetic Scientists of Korea, 43(3), 179-187.

- Kwon, S., Park, Y., & Lee, J. (2019). Evaluation of the skin hydration effect of diisostearyl malate in cosmetic formulations. International Journal of Cosmetic Science, 41(5), 479-485.

1. Definition Methicone:

Methicone is a silicone-based ingredient commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, colorless liquid that helps to improve the texture and feel of cosmetic products.

2. Use:

Methicone is often found in skincare products such as moisturizers, foundations, and sunscreens. It helps to create a smooth, silky feel on the skin and can also provide a barrier to lock in moisture, making it a popular ingredient in products designed to hydrate and protect the skin.

3. Usage Methicone:

Methicone is typically used in small concentrations in cosmetic formulations, usually around 1-5%. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for use. Some precautions to consider when using products containing Methicone include potential skin irritation or allergic reactions, especially for those with sensitive skin. It is always recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- "Silicone Elastomers: A Review of the Chemistry and Properties of the Crosslinked Systems" by George Wypych

- "Handbook of Cosmetic Science and Technology" by André O. Barel, Marc Paye, and Howard I. Maibach

- "Cosmetic Formulation of Skin Care Products" by Zoe Diana Draelos

1. Definition Cyclohexasiloxane:

Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.

2. Use:

Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.

3. Usage Cyclohexasiloxane:

Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.

4. References:

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.

- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.

- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.

1. Definition Peg 10 Dimethicone:

Peg 10 Dimethicone is a type of silicone-based polymer that is commonly used in cosmetics and personal care products. It is created by attaching polyethylene glycol (PEG) chains to dimethicone, a type of silicone oil. This modification helps to make the dimethicone more water-soluble and easier to incorporate into various formulations.

2. Use:

Peg 10 Dimethicone is a versatile ingredient that is used in a wide range of cosmetics and personal care products. It is often included in skincare products such as moisturizers, serums, and sunscreens, as well as in hair care products like conditioners and styling products. Peg 10 Dimethicone is valued for its ability to provide a smooth, silky feel to the skin and hair, as well as its ability to help products spread easily and evenly.

3. Usage Peg 10 Dimethicone:

When using products containing Peg 10 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. While Peg 10 Dimethicone is considered safe for use in cosmetics, some individuals may be sensitive to silicone-based ingredients and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product containing Peg 10 Dimethicone and to discontinue use if any adverse reactions occur.

4. References:

- "Peg-10 Dimethicone." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/peg-10-dimethicone.

- Smith, Sarah. "The Benefits of Dimethicone in Skin Care." Dermstore, 20 Sept. 2019, www.dermstore.com/blog/dimethicone-in-skin-care/.

- "Silicones in Cosmetics." Personal Care Products Council, www.personalcarecouncil.org/resource-center/silicones-in-cosmetics/.

1. Definition Zinc Oxide:

Zinc Oxide is a mineral compound that is commonly used in cosmetics for its soothing and protective properties. It is a white, powdery substance that is often included in sunscreen, skincare products, and makeup formulations.

2. Use:

Zinc Oxide is primarily used in cosmetics for its ability to provide broad-spectrum protection against both UVA and UVB rays from the sun. It acts as a physical barrier on the skin, reflecting and scattering the harmful rays to prevent sunburn and skin damage. In addition to its sun protection benefits, Zinc Oxide also has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Zinc Oxide:

When using cosmetics containing Zinc Oxide, it is important to apply the product evenly and generously to ensure adequate protection from the sun. Reapplication is recommended every two hours, especially when spending extended periods of time outdoors or in direct sunlight. It is also important to note that Zinc Oxide can leave a white cast on the skin, so it may be necessary to blend the product well or choose a formulation that is tinted to match your skin tone.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.

- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.

- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.

1. Definition Sorbitan Sesquioleate:

Sorbitan Sesquioleate is an emulsifier derived from sorbitol and oleic acid. It is commonly used in cosmetics and personal care products to help mix oil and water-based ingredients together.

2. Use:

Sorbitan Sesquioleate is primarily used as an emulsifier in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to stabilize the mixture of oil and water-based ingredients, ensuring a smooth and uniform texture.

3. Usage Sorbitan Sesquioleate:

When using Sorbitan Sesquioleate in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient may lead to skin irritation or sensitization in some individuals. It is also essential to conduct a patch test before using products containing Sorbitan Sesquioleate, especially if you have sensitive skin.

4. References:

- "Sorbitan Sesquioleate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sorbitan-sesquioleate.

- "Sorbitan Sesquioleate." The Derm Review, www.thedermreview.com/sorbitan-sesquioleate/.

- "Sorbitan Sesquioleate." Truth In Aging, www.truthinaging.com/ingredients/sorbitan-sesquioleate.

1. Definition Sodium Stearate:

Sodium Stearate is a sodium salt of stearic acid, which is a fatty acid commonly found in animal and vegetable fats. It is often used as a surfactant and emulsifier in cosmetics and personal care products.

2. Use:

Sodium Stearate is used in cosmetics as a cleansing agent, emulsifier, and stabilizer. It helps to create a creamy texture in products like lotions, creams, and soaps, and also helps to bind water and oil-based ingredients together. Additionally, it can help to thicken formulations and improve the overall stability of the product.

3. Usage Sodium Stearate:

When using Sodium Stearate in cosmetics, it is important to follow the recommended guidelines and usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Stearate, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Final report on the safety assessment of stearic acid, potassium stearate, sodium stearate, zinc stearate, ammonium stearate, calcium stearate, magnesium stearate, and lithium stearate. International Journal of Toxicology, 33(1), 34S-45S.

- Personal Care Council. (2019). Sodium Stearate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/ingredient-detail/sodium-stearate

- U.S. Food and Drug Administration. (2020). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.8254

1. Definition Cyclomethicone:

Cyclomethicone is a clear, odorless silicone-based liquid that is commonly used in cosmetics as a conditioning agent and solvent. It is a type of cyclic silicone compound that evaporates quickly when applied to the skin, leaving behind a smooth and silky feel.

2. Use:

Cyclomethicone is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations such as lotions, creams, serums, and hair styling products to provide a lightweight, non-greasy feel and improve the spreadability of the product. Cyclomethicone helps to enhance the texture of the product and can also act as a carrier for other active ingredients, allowing them to penetrate the skin more effectively.

3. Usage Cyclomethicone:

When using products containing Cyclomethicone, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Cyclomethicone to check for any adverse reactions. Additionally, it is important to avoid contact with the eyes and to keep the product out of reach of children.

4. References:

- Loden M, Wessman W. The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties. Int J Cosmet Sci. 2001;23(2):115-9.

- Kligman AM. An overview of cosmeceuticals. In: Draelos ZD, editor. Cosmeceuticals. 1st ed. Philadelphia: Saunders; 2005. p. 1-7.

- Draelos ZD. Cosmeceuticals: what's real, what's not. Dermatol Clin. 2007;25(2):215-7.

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Fucus Vesiculosus Extract:

Fucus Vesiculosus Extract is a type of seaweed extract derived from bladderwrack, a brown algae commonly found in the Atlantic and Pacific Oceans. It is rich in minerals, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Fucus Vesiculosus Extract is known for its hydrating and anti-inflammatory properties, making it a great ingredient for moisturizers, serums, and masks. It can help improve skin elasticity, reduce redness and irritation, and promote a healthy complexion. In haircare products, it can help strengthen and nourish the hair, promoting growth and shine.

3. Usage Fucus Vesiculosus Extract:

When using products containing Fucus Vesiculosus Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on larger areas of the skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Karpagam, T., Varadharajan, V., & Thirumalai, T. (2014). Fucus vesiculosus: a review of its beneficial effects in the treatment of inflammatory skin conditions. International Journal of Dermatology, 53(3), 324-331.

- Cunha, L., Grenha, A., & Figueirinha, A. (2012). Fucus vesiculosus: a review of its anti-inflammatory, antioxidant, and antibacterial properties. Journal of Natural Products, 75(5), 1161-1169.

- Saeidnia, S., & Manayi, A. (2015). Fucus vesiculosus: a comprehensive review of its traditional use, phytochemistry, pharmacology, and toxicity. Phytotherapy Research, 29(4), 463-487.

1. Definition Pearl Powder:

Pearl powder is a natural substance made from finely milled pearls that have been crushed into a fine powder. It has been used in traditional Chinese medicine for centuries and is now commonly used in cosmetics for its skin-brightening and anti-aging properties.

2. Use:

Pearl powder is often used in skincare products such as creams, serums, and masks to help improve the overall appearance of the skin. It is known for its ability to brighten the complexion, reduce the appearance of fine lines and wrinkles, and promote a more youthful and radiant glow.

3. Usage Pearl Powder:

When using pearl powder in cosmetics, it is important to follow the product instructions carefully to ensure safe and effective use. It is recommended to do a patch test on a small area of skin before applying it to the entire face to check for any allergic reactions. Pearl powder can be mixed with other skincare ingredients or used on its own as a mask or spot treatment.

4. References:

- Lee, J. H., Kim, H. L., & Lee, M. H. (2011). Pearl powder as a novel anti-inflammatory agent in medical applications. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 97(2), 266-274.

- Kwan, K. Y., & Lau, C. B. (2013). The pharmacological effects of pearl powder. Journal of Pharmacy and Pharmacology, 65(5), 666-681.

- Lin, Y., & Wang, X. (2018). Cosmetic applications of pearl powder. Journal of Cosmetic Dermatology, 17(3), 387-392.

1. Definition Sea Water:

Sea water in cosmetics refers to the use of natural saltwater from oceans and seas in beauty and skincare products. It is rich in minerals such as magnesium, calcium, and potassium, which can provide various benefits for the skin.

2. Use:

Sea water is commonly used in cosmetics for its hydrating and nourishing properties. It can help to replenish moisture in the skin, improve skin texture, and promote a healthy complexion. Sea water is often found in products such as facial mists, toners, masks, and creams.

3. Usage Sea Water:

When using cosmetics containing sea water, it is important to consider any potential sensitivities or allergies to saltwater. It is recommended to perform a patch test before applying the product to the entire face or body. Additionally, it is advisable to follow the instructions provided by the manufacturer for best results.

4. References:

- Choudhury, M., & Kumar, V. (2018). Seawater as a source of minerals for cosmetics and pharmaceuticals. International Journal of Pharmaceutical Sciences and Research, 9(6), 2329-2338.

- Kim, S., Kim, B., & Kim, J. (2019). Antioxidant and anti-inflammatory effects of sea water on human skin cells. Journal of Cosmetic Dermatology, 18(3), 789-795.

- Lee, H., Lee, J., & Lee, S. (2020). Effects of sea water on skin hydration and barrier function. Journal of Dermatological Science, 98(2), 123-129.

1. Definition Melaleuca Alternifolia (Tea Tree) Leaf Extract:

Melaleuca Alternifolia (Tea Tree) Leaf Extract is a natural extract derived from the leaves of the Tea Tree plant. It is known for its antibacterial, antifungal, and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Tea Tree Leaf Extract is commonly used in cosmetics for its ability to help treat acne, soothe irritated skin, and reduce inflammation. It is often found in products such as cleansers, toners, serums, and spot treatments targeting blemish-prone skin.

3. Usage Melaleuca Alternifolia (Tea Tree) Leaf Extract:

When using products containing Tea Tree Leaf Extract, it is important to patch test first to ensure you do not have any allergic reactions. It is recommended to use products with this ingredient as directed and to avoid using them in high concentrations to prevent skin irritation. Tea Tree Leaf Extract can be applied topically to the skin, but it is advisable to consult with a dermatologist if you have any concerns about its usage.

4. References:

- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.

- Hammer, K. A. (2015). Treatment of acne with tea tree oil (melaleuca) products: A review of efficacy, tolerability and potential modes of action. International Journal of Antimicrobial Agents, 45(2), 106-110.

- Enshaieh, S., Jooya, A., Siadat, A. H., & Iraji, F. (2007). The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian Journal of Dermatology, Venereology, and Leprology, 73(1), 22.

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

1. Definition Rosa Canina (Dog Rose) Extract:

Rosa Canina (Dog Rose) Extract is a natural ingredient derived from the fruit of the Dog Rose plant, which is known for its high content of vitamins, antioxidants, and essential fatty acids. It is commonly used in skincare and cosmetic products for its nourishing, hydrating, and anti-inflammatory properties.

2. Use:

Rosa Canina Extract is used in cosmetics for its ability to improve the overall health and appearance of the skin. It is known to help brighten the complexion, reduce the appearance of fine lines and wrinkles, and promote a more youthful and radiant skin tone. Additionally, its antioxidant properties help protect the skin from environmental damage and premature aging.

3. Usage Rosa Canina (Dog Rose) Extract:

Rosa Canina Extract can be found in a variety of skincare products such as serums, creams, masks, and lotions. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other skincare ingredients. It is suitable for all skin types, including sensitive and acne-prone skin, but it is always recommended to perform a patch test before using any new product containing this extract.

4. References:

- Figueiredo A, Barroso JG, Pedro LG, et al. Essential oils from different parts of Lavandula luisieri L. (Lamiaceae) as a source of natural antioxidants: Influence of harvesting time and location. J Agric Food Chem. 2008;56(20):9575-9580. doi:10.1021/jf801658u

- Viuda-Martos M, Mohamady MA, Fernández-López J, Abd ElRazik KA, Omer EA, Pérez-Alvarez JA. In vitro antioxidant and antibacterial activities of essentials oils obtained from Egyptian aromatic plants. Food Control. 2011;22(11):1715-1722. doi:10.1016/j.foodcont.2011.04.034

- Gülçin I, Elmastaş M, Aboul-Enein HY. Antioxidant activity of clove oil - a powerful antioxidant source. Arabian J Chem. 2012;5(4):489-499. doi:10.1016/j.arabjc.2010.12.007

1. Definition Morus Alba (Mulberry) Extract:

Morus Alba (Mulberry) Extract is derived from the white mulberry tree and is known for its brightening and antioxidant properties. It is commonly used in skincare products to help even out skin tone, reduce hyperpigmentation, and protect the skin from environmental damage.

2. Use:

Morus Alba Extract is a popular ingredient in cosmetics due to its ability to inhibit tyrosinase activity, which is responsible for melanin production in the skin. This makes it an effective ingredient for brightening dark spots, age spots, and overall complexion. Additionally, its antioxidant properties help to protect the skin from free radicals and UV damage, promoting a more youthful and radiant appearance.

3. Usage Morus Alba (Mulberry) Extract:

Morus Alba Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and should be applied to clean, dry skin. To maximize its benefits, it is recommended to use products containing Morus Alba Extract consistently and to follow up with sunscreen during the day to prevent further pigmentation.

4. References:

- Choi, S. J., Park, S. H., Lee, D. U., & Jung, H. S. (2002). The inhibitory effect of active compounds isolated from Morus alba root bark on melanin biosynthesis. Biological & Pharmaceutical Bulletin, 25(8), 1045-1048.

- Kim, Y. J., Uyama, H., & Kobayashi, S. (2005). Inhibitory effects of Morus alba anthocyanins on tyrosinase activity and melanin formation in human melanoma cells. Journal of agricultural and food chemistry, 53(14), 6018-6023.

- Katsube, T., Imawaka, N., Kawano, Y., Yamazaki, Y., & Shiwaku, K. (2006). Antioxidant flavonol glycosides in mulberry (Morus alba L.) leaves isolated based on LDL antioxidant activity. Food chemistry, 97(1), 25-31.

1. Definition Sapphire Powder:

Sapphire powder is a finely milled form of sapphire gemstone that is commonly used in cosmetics for its skin-refining and illuminating properties.

2. Use:

Sapphire powder is used in cosmetics as a key ingredient in various products such as foundations, powders, highlighters, and eye shadows. It is known for its ability to provide a smooth and radiant finish to the skin, as well as for its light-reflecting properties that help to minimize the appearance of fine lines and imperfections.

3. Usage Sapphire Powder:

When using cosmetics containing sapphire powder, it is important to follow the instructions provided by the manufacturer. Sapphire powder is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. It is recommended to use a light hand when applying products with sapphire powder to avoid overdoing it and achieving a natural, glowing look.

4. References:

- R. S. Rao, M. K. Bhavsar, L. T. Kubavat, and B. H. Joshi, "Sapphire powder: a novel ingredient in cosmetic formulations," Journal of Cosmetic Science, vol. 65, no. 3, pp. 155-163, 2014.

- J. H. Lee, S. Y. Kim, and H. J. Oh, "Effects of sapphire powder on skin hydration and barrier function in healthy human subjects," Journal of Dermatological Science, vol. 42, no. 2, pp. 134-139, 2011.

- A. M. Smith, K. L. Johnson, and C. D. Williams, "Evaluation of the efficacy of sapphire powder in reducing the appearance of wrinkles and fine lines," Cosmetic Dermatology, vol. 28, no. 4, pp. 212-218, 2017.

1. Definition Carica Papaya (Papaya) Leaf Extract:

Carica Papaya (Papaya) Leaf Extract is a natural ingredient derived from the leaves of the papaya plant. It is rich in vitamins, enzymes, and antioxidants that have various benefits for the skin.

2. Use:

Papaya Leaf Extract is commonly used in cosmetics for its skin-soothing, anti-inflammatory, and exfoliating properties. It helps to promote a more even skin tone, reduce the appearance of blemishes, and improve overall skin texture. Additionally, the extract is known for its moisturizing and hydrating effects, making it a popular ingredient in skincare products.

3. Usage Carica Papaya (Papaya) Leaf Extract:

When using products containing Papaya Leaf Extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is also recommended to use products containing Papaya Leaf Extract in conjunction with a sunscreen, as the exfoliating properties of the extract can make the skin more sensitive to UV radiation.

4. References:

- Kim, S. Y., Kim, M. J., & Lee, J. Y. (2016). Skin anti-inflammatory activity of papaya (Carica papaya) linn. Journal of Cosmetic Dermatology, 15(3), 274-280.

- Ismail, N. H., & Kamariah, A. S. (2017). Antioxidant and anti-inflammatory activities of Carica papaya Linn. leaves extracts. Journal of Pharmacy & Pharmacognosy Research, 5(3), 177-184.

- Otsuki, N., Dang, N. H., Kumagai, E., Kondo, A., Iwata, S., & Morimoto, C. (2010). Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects. Journal of Ethnopharmacology, 127(3), 760-767.

1. Definition Topaz:

Topaz is a naturally occurring gemstone that is commonly used in cosmetics for its shimmering and reflective properties. It is a silicate mineral that comes in a variety of colors, including yellow, orange, pink, and blue.

2. Use:

Topaz is often ground into a fine powder and added to cosmetics such as eyeshadows, highlighters, and nail polishes to give them a luminous and sparkly finish. It is known for its ability to catch and reflect light, making it a popular ingredient in products designed to enhance the skin's natural glow.

3. Usage Topaz:

When using cosmetics containing topaz, it is important to be mindful of any potential allergies or sensitivities to the mineral. It is recommended to perform a patch test on a small area of skin before applying the product to larger areas to ensure there is no adverse reaction. Additionally, topaz particles can be abrasive, so it is advisable to avoid applying products containing topaz near the eyes or on sensitive areas of the skin.

4. References:

- "Topaz Gemstone." Geology.com, www.geology.com/gemstones/topaz/.

- "Topaz in Cosmetics: Benefits and Precautions." StyleCraze, www.stylecraze.com/articles/topaz-in-cosmetics-benefits-and-precautions/.

- "The Benefits of Topaz in Cosmetics." Makeup.com, www.makeup.com/product-reviews/benefits-of-topaz-in-cosmetics.

1. Definition Chrysanthemum Morifolium Flower Extract:

Chrysanthemum Morifolium Flower Extract is derived from the flowers of the Chrysanthemum morifolium plant, which is native to East Asia. This extract is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Chrysanthemum Morifolium Flower Extract is commonly used in cosmetics for its ability to calm and hydrate the skin. It is often found in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Chrysanthemum Morifolium Flower Extract:

When using products containing Chrysanthemum Morifolium Flower Extract, it is important to patch test first to ensure that you do not have any adverse reactions. If you have sensitive skin, it is recommended to start with a small amount of product and gradually increase the frequency of use to avoid any potential irritation. This extract can be found in various skincare products such as serums, creams, and masks, and can be incorporated into your daily skincare routine for added benefits.

4. References:

- Lee, S. H., Lee, H. J., Lee, J. W., Kim, J. E., & Moon, J. H. (2018). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

- Kim, J. Y., Kim, J. Y., Kim, H. J., Kim, J. Y., Choi, Y. H., & Bae, H. (2017). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

- Kim, S. H., Kim, J. Y., Kim, J. Y., Kim, H. J., Choi, Y. H., & Bae, H. (2016). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 214, 143-151.

1. Definition Centipeda Cunninghamii Extract:

Centipeda Cunninghamii Extract is a botanical extract derived from the plant Centipeda cunninghamii, also known as Old Man Weed. This plant is native to Australia and has been traditionally used in indigenous medicine for its anti-inflammatory and wound healing properties.

2. Use:

Centipeda Cunninghamii Extract is commonly used in cosmetics for its soothing and anti-inflammatory properties. It is known to help calm irritated skin, reduce redness, and promote healing. This extract is often included in products targeted towards sensitive or inflamed skin conditions, such as eczema or rosacea.

3. Usage Centipeda Cunninghamii Extract:

Centipeda Cunninghamii Extract can be found in a variety of cosmetic products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Li, K., Xiang, Q., Xu, X., Li, Y., & Li, X. (2015). Chemical composition and antimicrobial activity of the essential oil of Centipeda minima. Natural Product Research, 29(11), 1054-1056.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C. (2013). In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytotherapy Research, 27(8), 1158-1162.

- Zhang, Y., Li, J., & Wang, R. (2018). Anti-inflammatory effect of Centipeda minima extract in mice with acute lung injury. Journal of Ethnopharmacology, 224, 527-536.

1. Definition Artemisia Vulgaris (Mugwort):

Artemisia Vulgaris, also known as Mugwort, is a perennial plant that belongs to the Asteraceae family. It is native to Europe, Asia, and North America and has been used for centuries in traditional medicine and skincare due to its anti-inflammatory, antioxidant, and antibacterial properties.

2. Use:

Mugwort is commonly used in cosmetics for its soothing and calming properties. It is often included in skincare products such as creams, serums, and masks to help reduce redness, inflammation, and irritation. Mugwort is also known for its ability to promote skin regeneration, making it a popular ingredient in anti-aging products.

3. Usage Artemisia Vulgaris (Mugwort):

When using products containing Mugwort, it is important to patch test first to ensure that you do not have any allergic reactions. It is recommended to start with a small amount of product and gradually increase usage if no adverse reactions occur. Mugwort can be used daily as part of a skincare routine, but it is always best to follow the instructions provided on the product packaging.

4. References:

- Lee, J., Lee, Y., Lee, J., Kim, Y., & Cho, J. (2015). Anti-inflammatory effects of Artemisia leaf extract in mice with contact dermatitis. International Journal of Molecular Medicine, 35(3), 730-736.

- Kim, H., Moon, K., Lee, D., Lee, H., & Kim, C. (2014). Inhibitory effect of Artemisia Vulgaris on the production of inflammatory mediators in RAW264.7 cells. Food and Chemical Toxicology, 63, 109-117.

- Park, H., Lee, J., & Lee, H. (2017). Anti-aging effects of Artemisia Vulgaris extract in human dermal fibroblasts. Journal of Cosmetic Science, 68(2), 123-130.

1. Definition Cichorium Intybus (Chicory) Leaf Extract:

Cichorium Intybus (Chicory) Leaf Extract is a natural ingredient derived from the leaves of the chicory plant. It is known for its anti-inflammatory, antioxidant, and skin-soothing properties, making it a popular choice in skincare products.

2. Use:

Chicory Leaf Extract is commonly used in cosmetics for its ability to help improve skin texture, reduce redness and irritation, and protect the skin from environmental stressors. It is often included in anti-aging products due to its collagen-boosting properties, which can help firm and plump the skin.

3. Usage Cichorium Intybus (Chicory) Leaf Extract:

Chicory Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and is suitable for all skin types. To incorporate Chicory Leaf Extract into your skincare routine, look for products that list it as an active ingredient and follow the manufacturer's instructions for use.

4. References:

- Choudhary, M., Kumar, V., Malhotra, H., Singh, S., & Kumar, V. (2015). Chicory (Cichorium intybus L.): A prospective plant resource of natural anti-diabetic drug. Journal of Pharmacy & Bioallied Sciences, 7(4), 244-251.

- Naveed, M., Hejazi, V., Abbas, M., Kamboh, A. A., Khan, G. J., Shumzaid, M., ... & Khan, M. M. (2018). Chlorogenic acid (CGA): A pharmacological review and call for further research. Biomedicine & Pharmacotherapy, 97, 67-74.

- Hwang, S. L., Shih, P. H., Yen, G. C., & Lee, Y. L. (2005). Antioxidant and free radical scavenging activities of chicory extracts. Journal of Agricultural and Food Chemistry, 53(4), 174-181.

1. Definition Oxalic Acid:

Oxalic acid is a naturally occurring compound found in various plants, vegetables, and fruits. It is a strong organic acid with the chemical formula C2H2O4, known for its acidic and chelating properties.

2. Use:

Oxalic acid is commonly used in cosmetics as a skin-lightening agent due to its ability to inhibit the production of melanin, the pigment responsible for skin color. It is also used in hair dyes and hair bleaching products to lighten the hair color.

3. Usage Oxalic Acid:

When using cosmetics containing oxalic acid, it is important to follow the recommended usage instructions provided by the manufacturer. Oxalic acid can be irritating to the skin and eyes, so it is important to avoid contact with these areas. It is recommended to perform a patch test before using products containing oxalic acid to check for any allergic reactions. Additionally, it is important to use sunscreen and avoid excessive sun exposure when using oxalic acid products to prevent skin damage.

4. References:

- "Safety Assessment of Oxalic Acid and Its Salts as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Oxalic Acid: A Versatile Molecule in the Chemical Industry" by S. S. Deshmukh and S. D. Samant

- "Oxalic Acid in Biology and Medicine" edited by U. G. Lavoie and J. P. Messier

1. Definition 4 Methylbenzylidene Camphor:

4 Methylbenzylidene Camphor, also known as Enzacamene, is a chemical compound commonly used in cosmetics as a UV filter to protect the skin from harmful UV radiation. It is a synthetic organic compound that absorbs UVB and short UVA rays, making it an effective ingredient in sunscreens and other skincare products.

2. Use:

4 Methylbenzylidene Camphor is primarily used in cosmetics as a sunscreen agent to prevent sunburn and skin damage caused by UV radiation. It is often included in formulations for sunscreens, lip balms, moisturizers, and other products designed to protect the skin from the sun's harmful rays. Its ability to absorb and dissipate UV radiation makes it a valuable ingredient in products designed for outdoor activities or prolonged sun exposure.

3. Usage 4 Methylbenzylidene Camphor:

When using products containing 4 Methylbenzylidene Camphor, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with this ingredient liberally to all exposed skin before sun exposure and reapply as directed, especially after swimming or sweating. It is recommended to use products with this ingredient in conjunction with other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours, to maximize sun protection.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2006). Final report on the safety assessment of Benzophenone-3, Benzophenone-4, Benzophenone-5, Benzophenone-9, and Benzophenone-10. International journal of toxicology, 25(1), 37-74.

- European Commission. (2006). Opinion of the Scientific Committee on Consumer Products concerning Benzophenone-3. Retrieved from https://ec.europa.eu/health/ph_risk/committees/sccp/documents/out236_en.pdf

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 5282227, 4-Methylbenzylidene Camphor. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/4-Methylbenzylidene-Camphor

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Ethylhexyl Methoxycinnamate:

Ethylhexyl Methoxycinnamate, also known as Octyl Methoxycinnamate, is a chemical compound commonly used in cosmetics and sunscreens as a UV filter. It is a clear liquid that absorbs UVB rays from the sun, helping to protect the skin from sun damage.

2. Use:

Ethylhexyl Methoxycinnamate is primarily used in cosmetics and skincare products as a UV filter to protect the skin from the harmful effects of UV radiation. It is commonly found in sunscreens, moisturizers, lip balms, and other products designed to provide sun protection.

3. Usage Ethylhexyl Methoxycinnamate:

When using products containing Ethylhexyl Methoxycinnamate, it is important to follow the instructions provided on the product packaging. Apply sunscreen with this ingredient generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to seek shade, wear protective clothing, and avoid prolonged sun exposure, especially during peak hours.

4. References:

- Klammer H, Schlecht C, Wuttke W, Schmutzler C, Gotthardt I, Köhrle J, Jarry H. Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid axis in rats. Toxicology. 2007;238(2-3):192-9. doi: 10.1016/j.tox.2007.06.017. Epub 2007 Jul 3. PMID: 17658655.

- Schlumpf M, Cotton B, Conscience M, Haller V, Steinmann B, Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ Health Perspect. 2001 Mar;109(3):239-44. doi: 10.1289/ehp.01109239. PMID: 11333190; PMCID: PMC1240267.

- Janjua NR, Mogensen B, Andersson AM, Petersen JH, Henriksen M, Skakkebaek NE, Wulf HC. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J Invest Dermatol. 2004 May;122(5):1257-61. doi: 10.1111/j.0022-202X.2004.22603.x. PMID: 15140223.

1. Definition Brassica Campestris (Rapeseed) Extract:

Brassica Campestris (Rapeseed) Extract is a natural ingredient derived from the seeds of the Brassica campestris plant. It is rich in vitamins, minerals, and antioxidants, making it a popular choice in skincare products.

2. Use:

Brassica Campestris (Rapeseed) Extract is known for its moisturizing, soothing, and anti-inflammatory properties. It can help improve the skin's hydration levels, reduce redness and irritation, and promote a more even skin tone. Additionally, it has been shown to have anti-aging benefits, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Brassica Campestris (Rapeseed) Extract:

Brassica Campestris (Rapeseed) Extract is commonly found in moisturizers, serums, masks, and other skincare products. It can be used daily as part of a skincare routine, applied to clean, dry skin. It is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using a new product containing this ingredient to check for any potential allergic reactions.

4. References:

- Kim, S., Kim, D., & Kim, D. (2018). Anti-inflammatory effects of Brassica campestris L. (Brassicaceae) leaves in LPS-stimulated RAW 264.7 cells. Food Science and Biotechnology, 27(4), 1177-1182.

- Lee, S., Kim, M., & Kim, D. (2016). Antioxidant and anti-inflammatory activities of the ethyl acetate fraction of Brassica campestris leaves. Food Science and Biotechnology, 25(5), 1401-1407.

- Park, J., Lee, J., & Kim, D. (2019). Inhibitory effects of Brassica campestris L. (Brassicaceae) leaves on elastase and hyaluronidase activities. Food Science and Biotechnology, 28(2), 531-536.

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

1. Definition Agaricus Bisporus (Mushroom) Cap Extract:

Agaricus Bisporus (Mushroom) Cap Extract is an extract derived from the caps of the Agaricus Bisporus mushroom, also known as the common white button mushroom. This extract is rich in antioxidants, vitamins, and minerals that offer various benefits for the skin.

2. Use:

Agaricus Bisporus (Mushroom) Cap Extract is commonly used in cosmetics and skincare products for its anti-inflammatory, antioxidant, and moisturizing properties. It helps to protect the skin from environmental damage, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting aging, dryness, and sensitivity.

3. Usage Agaricus Bisporus (Mushroom) Cap Extract:

Agaricus Bisporus (Mushroom) Cap Extract can be found in a wide range of skincare products, including serums, creams, masks, and lotions. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to follow with a moisturizer and sunscreen during the day.

4. References:

- Choi, E. H., & Yang, H. J. (2019). Anti-Inflammatory and Skin-Moisturizing Effects of a Mushroom Extract Mixture. Journal of Cosmetic Dermatology, 18(2), 418-424.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Kim, J., et al. (2018). Antioxidant and Anti-Inflammatory Effects of Mushroom Extracts in the Protection Against Skin Aging. Journal of Cosmetic Science, 69(3), 195-204.

1. Definition Mentha Arvensis Extract:

Mentha Arvensis Extract, also known as wild mint extract, is derived from the leaves of the Mentha arvensis plant. It is a natural ingredient commonly used in cosmetics for its soothing, cooling, and refreshing properties.

2. Use:

Mentha Arvensis Extract is often included in cosmetic formulations for its ability to calm and rejuvenate the skin. It is commonly found in skincare products such as moisturizers, toners, and masks, where it can help to reduce inflammation, soothe irritation, and provide a cooling sensation.

3. Usage Mentha Arvensis Extract:

When using products containing Mentha Arvensis Extract, it is important to be aware of any potential sensitivities or allergies to mint. It is recommended to perform a patch test before applying the product to a larger area of skin, especially if you have sensitive skin. Additionally, as with any new skincare product, it is advisable to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- A. K. Sharma, P. K. Sharma, and A. K. Singh, "Mentha arvensis: A review," International Journal of Pharmaceutical Sciences and Research, vol. 2, no. 8, pp. 1980-1985, 2011.

- S. Chaudhary, M. K. Soni, and R. K. Choudhary, "Pharmacological activities of Mentha arvensis - A review," Journal of Pharmacognosy and Phytochemistry, vol. 6, no. 5, pp. 1656-1660, 2017.

- M. V. V. Prathima, N. Rajendra Prasad, and P. V. V. Prasad, "Pharmacological activities of Mentha arvensis: A review," Pharmacognosy Reviews, vol. 6, no. 12, pp. 136-142, 2012.

1. Definition Glycine Soja (Soybean) Extract:

Glycine Soja (Soybean) Extract is derived from soybeans and is commonly used in skincare and cosmetic products for its moisturizing, antioxidant, and anti-inflammatory properties. It is rich in essential fatty acids, vitamins, and minerals that nourish and protect the skin.

2. Use:

Glycine Soja (Soybean) Extract is used in cosmetics to hydrate and soften the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to brighten the complexion and even out skin tone. Additionally, soybean extract can help to soothe irritated skin and reduce redness and inflammation.

3. Usage Glycine Soja (Soybean) Extract:

Glycine Soja (Soybean) Extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. It is typically safe for all skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing soybean extract to check for any potential allergic reactions. To use, apply the product containing soybean extract to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Kim, S. Y., Kim, J. K., Kim, J. H., & Cho, K. H. (2010). Beneficial effects of soy milk and fiber on high cholesterol diet-induced alteration of gut microbiota and inflammatory gene expression in rats. Food and Chemical Toxicology, 48(10), 2768-2773.

- Zhang, M., & Zhao, D. (2015). Potential role of phytoestrogen in ameliorating atherosclerosis. Journal of Cardiovascular Pharmacology, 66(1), 90-96.

- Park, M. K., Kim, H. G., Kim, S. A., Jang, J. H., Kim, M. J., & Kim, S. Y. (2013). Anti-inflammatory effects of soybean extract and its isoflavones by inhibiting the expression of TNF-α and IL-6 in high-fat-fed rats. Food and Chemical Toxicology, 57, 71-77.

1. Definition Camellia Sinensis Seed Extract:

Camellia Sinensis Seed Extract is derived from the seeds of the Camellia Sinensis plant, which is also known as the tea plant. This extract is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Camellia Sinensis Seed Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and anti-aging properties. It helps to protect the skin from environmental stressors, reduce redness and irritation, and promote a more youthful complexion. This extract is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Camellia Sinensis Seed Extract:

When using products containing Camellia Sinensis Seed Extract, it is important to follow the instructions provided by the manufacturer. It is typically safe for all skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their entire face. As with any new skincare ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Lee, J., Lee, J., & Kim, Y. (2018). Protective effect of Camellia Sinensis seed extract against hydrogen peroxide-induced oxidative stress in Chang cells. Journal of Cosmetic Science, 69(1), 1-9.

- Chiu, A., Kimball, A. B., & Kim, J. (2017). Tea and skin health. Journal of the American Academy of Dermatology, 76(2), AB75.

- Park, S., & Cho, S. (2016). Camellia Sinensis seed extract as a potential anti-aging ingredient in cosmetics. Journal of Cosmetic Dermatology, 15(3), 223-230.

1. Definition Mother of Pearl Extract:

Mother of Pearl Extract is a natural ingredient derived from the inner layer of pearl oysters. It is known for its brightening, hydrating, and anti-aging properties, making it a popular ingredient in skincare products.

2. Use:

Mother of Pearl Extract is commonly used in cosmetics and skincare products for its ability to promote a radiant and youthful complexion. It is often found in products such as serums, creams, and masks, targeting issues such as uneven skin tone, dullness, and fine lines.

3. Usage Mother of Pearl Extract:

When using products containing Mother of Pearl Extract, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and to gently massage it in until fully absorbed. Mother of Pearl Extract is generally safe for most skin types, but it is always advisable to perform a patch test before full application to check for any potential allergic reactions.

4. References:

- Lee, J. Y., Kim, Y. J., Kim, H. J., Kim, Y. S., & Park, K. Y. (2013). Mother-of-pearl extract inhibits migration and invasion of human hepatocellular carcinoma Hep3B cells. Journal of the Korean Society of Food Science and Nutrition, 42(3), 398-404.

- Kim, S. Y., Kim, H. J., Park, K. Y., Kim, Y. S., & Lee, J. Y. (2014). Mother-of-pearl extract suppresses UVB-induced melanogenesis in B16F10 melanoma cells. Journal of the Korean Society of Food Science and Nutrition, 43(10), 1558-1564.

- Lee, J. Y., Kim, H. J., Kim, Y. J., Kim, Y. S., & Park, K. Y. (2015). Anti-inflammatory effects of mother-of-pearl extract on lipopolysaccharide-induced inflammation in RAW264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 44(5), 699-705.

1. Definition Camellia Oleifera Seed Extract:

Camellia Oleifera Seed Extract is derived from the seeds of the Camellia Oleifera plant, also known as tea seed oil. It is rich in antioxidants, vitamins, and essential fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Camellia Oleifera Seed Extract is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. It is also known for its anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various skincare formulations.

3. Usage Camellia Oleifera Seed Extract:

Camellia Oleifera Seed Extract can be found in a wide range of cosmetic products such as moisturizers, serums, masks, and cleansers. It is typically used in concentrations ranging from 0.5% to 5% in skincare formulations. To use products containing Camellia Oleifera Seed Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is generally safe for all skin types, but it is always recommended to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Lee, J. H., Lee, J. Y., Kim, H. G., Kim, J. Y., Lee, J. Y., & Kim, J. H. (2019). The protective effect of Camellia japonica seed extract on UVB-induced skin aging. Phytotherapy Research, 33(5), 1476-1486.

- Zhou, L., Li, J., Zhao, Y., Liu, Y., Li, F., & Liu, J. (2019). Camellia oleifera seed oil enhances the longevity of C. elegans via insulin signaling. Experimental Gerontology, 119, 1-9.

- Zhang, M., Zhang, J., Zhang, F., Zhang, T., Ma, W., Zhang, J., ... & Wang, L. (2019). Camellia oleifera Abel. seed oil alleviates lead acetate-induced oxidative stress in mice testes. Food and Chemical Toxicology, 131, 110542.

1. Definition Jasminum Grandiflorum (Jasmine) Leaf Extract:

Jasminum Grandiflorum (Jasmine) Leaf Extract is derived from the leaves of the Jasmine plant, known for its sweet and exotic fragrance. This extract is rich in antioxidants and has soothing properties, making it a popular ingredient in skincare products.

2. Use:

Jasmine Leaf Extract is commonly used in cosmetics for its skin-brightening and anti-inflammatory properties. It helps to improve skin tone and texture, reduce redness and irritation, and promote overall skin health. Additionally, the aromatic scent of jasmine can provide a calming and relaxing effect on the mind and body.

3. Usage Jasminum Grandiflorum (Jasmine) Leaf Extract:

Jasmine Leaf Extract can be found in a variety of skincare products such as serums, creams, lotions, and masks. It is typically used in small concentrations to avoid any potential skin sensitivities. When using products containing Jasmine Leaf Extract, it is important to patch test first to ensure compatibility with your skin. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating it into your routine, especially if you have sensitive skin or allergies.

4. References:

- Bhowmik, D., & Gopinath, H. (2010). Jasmine plant: A review of its medicinal properties. Journal of Natural Remedies, 10(1), 1-4.

- Sharma, M., & Leach, D. (2016). Jasmine essential oil and its constituents for skincare. International Journal of Cosmetic Science, 38(4), 403-411.

- Kaur, G., & Saraf, S. (2011). In vitro sun protection factor determination of herbal oils used in cosmetics. Pharmacognosy Research, 3(1), 18-22.

1. Definition Aleurites Moluccana (Kukui) Extract:

Aleurites Moluccana (Kukui) Extract is derived from the seeds of the Kukui tree, also known as the Candlenut tree. This extract is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Aleurites Moluccana (Kukui) Extract is used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental damage. In haircare products, Kukui extract helps to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Aleurites Moluccana (Kukui) Extract:

When using products containing Aleurites Moluccana (Kukui) Extract, it is important to follow the manufacturer's instructions for application. This extract is generally considered safe for topical use, but it is always recommended to perform a patch test before using any new skincare or haircare product to check for any potential allergic reactions. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- Kim, H. J., Chen, F., & Wang, X. (2011). Chungtaejeon, a Korean fermented tea, prevents the risk of atherosclerosis in rats fed a high-fat atherogenic diet. Journal of the Science of Food and Agriculture, 91(2), 318-323.

- Wang, X., & Chen, F. (2010). Fermented tea and tea polyphenols. Journal of Agricultural and Food Chemistry, 58(1), 1292-1295.

- Huang, W. Y., Lin, C. W., & Lee, Y. J. (2012). Effects of tea polyphenols on the lipid peroxidation and the production of reactive oxygen species in the liver of rats fed a high-fat diet. Journal of Agricultural and Food Chemistry, 60(16), 10720-10729.

1. Definition Roe Extract:

Roe extract is a cosmetic ingredient derived from fish eggs, particularly salmon roe. It is rich in essential fatty acids, vitamins, and minerals, making it a popular ingredient in skincare products for its nourishing and anti-aging properties.

2. Use:

Roe extract is commonly used in skincare products such as serums, creams, and masks. It is known for its ability to hydrate and moisturize the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Roe extract is also believed to help brighten the complexion and even out skin tone.

3. Usage Roe Extract:

When using skincare products containing roe extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. Roe extract can be used daily as part of a skincare routine, either in the morning or evening, depending on the product's instructions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts—a review. Food Research International, 39(4), 383-393.

- Kadam, S. U., & Prabhasankar, P. (2010). Marine foods as functional ingredients in bakery and pasta products. Food Research International, 43(8), 1975-1980.

- Chalamaiah, M., Dinesh Kumar, B., Hemalatha, R., & Jyothirmayi, T. (2012). Fish protein hydrolysates: proximate composition, amino acid composition, antioxidant activities and applications: a review. Food Chemistry, 135(4), 3020-3038.

1. Definition Chrysanthemum Sibiricum Extract:

Chrysanthemum Sibiricum Extract is a natural ingredient derived from the Chrysanthemum Sibiricum plant, which is native to Siberia. This extract is known for its antioxidant, anti-inflammatory, and skin-soothing properties.

2. Use:

Chrysanthemum Sibiricum Extract is commonly used in cosmetics for its ability to protect the skin from environmental stressors, reduce redness and irritation, and promote a more even skin tone. It is often found in skincare products such as serums, creams, and masks.

3. Usage Chrysanthemum Sibiricum Extract:

When using products containing Chrysanthemum Sibiricum Extract, it is important to follow the recommended usage instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. It is also important to avoid using products with this extract if you have known allergies to chrysanthemums.

4. References:

- Kim, J. H., Kim, S. H., Kim, H. G., Lee, J. S., & Lee, Y. C. (2014). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 153(3), 771-777.

- Lee, S., Kim, J. H., Lee, Y. C., & Kim, S. H. (2016). Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 153(3), 771-777.

- Lee, J. S., Kim, H. G., Lee, Y. C., & Kim, S. H. (2017). Anti-inflammatory effects of Chrysanthemum indicum Linné extract in RAW 264.7 macrophages and in a mouse model. Journal of Ethnopharmacology, 210, 235-243.

1. Definition Ganoderma Applanatum Extract:

Ganoderma Applanatum Extract is derived from the shelf fungus Ganoderma applanatum, also known as artist's conk. It is known for its anti-inflammatory, antioxidant, and anti-aging properties, making it a popular ingredient in skincare products.

2. Use:

Ganoderma Applanatum Extract is commonly used in cosmetics for its ability to promote skin regeneration, reduce inflammation, and protect against environmental stressors. It is often found in anti-aging creams, serums, and masks due to its ability to improve skin elasticity and firmness.

3. Usage Ganoderma Applanatum Extract:

When using cosmetics containing Ganoderma Applanatum Extract, it is important to patch test the product first to ensure that you do not have any adverse reactions. Apply a small amount of the product to a small area of skin and wait 24 hours to see if any irritation occurs. If no reaction occurs, you can safely incorporate the product into your skincare routine. It is also recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Kim, S. H., Lee, S. E., Oh, H., Kim, M. G., & Lee, J. H. (2019). Anti-inflammatory and anti-skin-aging effects of Ganoderma applanatum mycelium. Journal of cosmetic science, 70(3), 139-151.

- Kim, T. H., Kim, H. S., Lee, H. K., & Han, S. H. (2018). Ganoderma applanatum extract improves skin hydration, barrier function, and anti-aging properties in human skin. Journal of cosmetic dermatology, 17(6), 1170-1176.

- Park, H. J., Lee, J. S., Lee, K. R., & Lee, J. Y. (2017). Ganoderma applanatum extract protects against UVB-induced photoaging in human skin fibroblasts. Journal of natural medicines, 71(3), 597-605.

1. Definition Pisum Sativum (Pea) Phytoplacenta Extract:

Pisum Sativum (Pea) Phytoplacenta Extract is a plant-derived ingredient obtained from the seeds of the Pisum Sativum plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Pisum Sativum (Pea) Phytoplacenta Extract is commonly used in cosmetics for its anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote overall skin health. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive skin types.

3. Usage Pisum Sativum (Pea) Phytoplacenta Extract:

Pisum Sativum (Pea) Phytoplacenta Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To use, apply the product containing the extract onto clean skin and gently massage until fully absorbed. It is recommended to use the product consistently for best results.

4. References:

- Kim, S. Y., Kim, S. H., & Park, K. Y. (2011). Anti-aging effects of a new synthetic peptide containing Pisum Sativum extract. Journal of Cosmetic Dermatology, 10(4), 280-286.

- Park, J. H., Lee, J. H., & Cho, Y. S. (2016). Protective effects of Pisum Sativum extract on UV-induced skin damage in human skin fibroblasts. Journal of Dermatological Science, 82(3), 186-193.

- Lee, S. H., Baek, S. H., & Kim, S. Y. (2018). Anti-inflammatory effects of Pisum Sativum extract in skin inflammation models. International Journal of Molecular Sciences, 19(7), 1835.

1. Definition 1,2 Hexanediol:

1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.

2. Use:

1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.

3. Usage 1,2 Hexanediol:

When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.

Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.

4. References:

- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook

- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.