Full ingredients list BIO HEAL BOH Probioderm Lifting Eye & ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1		Polyglyceryl 3 Methylglucose Distearate (Skin Conditioning, Emollient, Surfactant, Emulsifying)	Fungal Acne Trigger
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	1,2-Hexanediol (Solvent)
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1		Chlorella Vulgaris Extract (Skin Conditioning)
1	A	Hydrogenated Vegetable Oil (Skin Conditioning, Emollient, Viscosity Increasing Agent)	Bad for oily skin
1	A	Copernicia Cerifera (Carnauba) Wax (Epilating Agent, Depilatory)	Fungal Acne Trigger
1	A	Hydrolyzed Corn Starch (Skin Conditioning, Humectant, Viscosity Controlling, Binding)
1		Lactobacillus Ferment (Skin Conditioning)
1		Bacillus Ferment (Skin Conditioning)
1	A	Xylose (Masking, Fragrance, Humectant, Skin Conditioning, Flavoring Agent)
1		Phaseolus Lunatus (Green Bean) Seed Extract (Emollient)
1	A	Diisostearyl Malate (Skin Conditioning, Emollient, Surfactant)
1		Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer (Viscosity Controlling, Emulsion Stabilising)
1	A	Glucose (Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous)
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	Fructose (Humectant, Flavoring Agent)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
1		Fructooligosaccharides (Humectant, Skin Conditioning)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1	A	Stearyl Dimethicone (Skin Conditioning, Emollient)	Silicone
1	A	Sorbitan Isostearate (Emulsifying, Surfactant)	Fungal Acne Trigger
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1		Adenosine (Skin Conditioning)	Anti Aging
1		Trisodium Ethylenediamine Disuccinate (Chelating Agent)
1		Glyceryl Acrylate/Acrylic Acid Copolymer (Humectant, Viscosity Controlling)
1	A	Sucrose (Humectant, Skin Conditioning, Soothing, Flavoring Agent)
1		Ceramide 3 (Hair Conditioning, Skin Conditioning)	Anti Aging
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
1		Lactobionic Acid (pH adjusting agent, pH adjusting agent)	Anti Aging
1		Micrococcus Lysate (Skin Conditioning)
1		Tocopherol	Good for dry skin Anti Aging
1		Dipeptide Diaminobutyroyl Benzylamide Diacetate (Skin Conditioning)
1		Palmitoyl Tripeptide 5 (Skin Conditioning)
1	A	Cetyl Hydroxyethylcellulose (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Film Forming)
1		Rutin (Hair Conditioning, Skin Conditioning, Antioxidant)	Good for sensitive skin
1		Hexapeptide 2 (Skin Conditioning)
1		Acetyl Tetrapeptide 5 (Humectant)
1	A	Dextran (Viscosity Controlling, Binding Agent, Binding, Bulking Agent)
1	A	Tripeptide 1 (Skin Conditioning)
1		Palmitoyl Hexapeptide 12 (Skin Conditioning)
1	A	Biotin (Hair Conditioning, Skin Conditioning, Antiseborrhoeic)
1		Acetyl Hexapeptide 8 (Humectant, Skin Conditioning)
1	A	Palmitoyl Tetrapeptide 7 (Skin Conditioning)
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1		Hexapeptide 9 (Skin Conditioning)
1		Palmitoyl Pentapeptide 4 (Skin Conditioning)
1	A	Copper Tripeptide 1 (Skin Conditioning)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Polyglyceryl 3 Methylglucose Distearate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Polyglyceryl 3 Methylglucose Distearate:

Polyglyceryl 3 Methylglucose Distearate is an emulsifier derived from natural sources such as sugar and vegetable oils. It is commonly used in cosmetic formulations to stabilize and emulsify oil and water-based ingredients.

2. Use:

Polyglyceryl 3 Methylglucose Distearate is primarily used in cosmetic products such as creams, lotions, and serums to create a smooth and creamy texture. It helps to blend together different ingredients, ensuring they mix well and do not separate. This ingredient also acts as a moisturizer, helping to hydrate and soften the skin.

3. Usage Polyglyceryl 3 Methylglucose Distearate:

When using products containing Polyglyceryl 3 Methylglucose Distearate, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-3 Methylglucose Distearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." Truth in Aging, www.truthinaging.com/ingredients/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." The Derm Review, www.thedermreview.com/polyglyceryl-3-methylglucose-distearate/.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Chlorella Vulgaris Extract

Function: Skin Conditioning

1. Definition Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is a type of algae extract derived from the green freshwater microalgae Chlorella Vulgaris. It is rich in essential nutrients such as vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Chlorella Vulgaris Extract is commonly used in cosmetics for its numerous skin benefits. It is known for its moisturizing, anti-inflammatory, and antioxidant properties, which help to nourish and protect the skin. Additionally, it can help to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health.

3. Usage Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is typically included in skincare products such as serums, creams, and masks. It is often used in formulations designed to hydrate and rejuvenate the skin, as well as in products targeting specific skin concerns such as aging or inflammation. When using products containing Chlorella Vulgaris Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to regular use to check for any potential allergic reactions.

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

Hydrogenated Vegetable Oil

Function: Skin Conditioning, Emollient, Viscosity Increasing Agent

1. Definition Hydrogenated Vegetable Oil:

Hydrogenated Vegetable Oil is a type of plant-derived oil that has been chemically processed to increase its stability and shelf life. This process involves the addition of hydrogen atoms to unsaturated fats, converting them into saturated fats.

2. Use:

Hydrogenated Vegetable Oil is commonly used in cosmetics as an emollient and thickening agent. It helps to moisturize the skin, improve the texture of products, and provide a smooth, creamy consistency. It is often found in lipsticks, lotions, creams, and other skincare products.

3. Usage Hydrogenated Vegetable Oil:

When using products containing Hydrogenated Vegetable Oil, it is important to be aware of any potential sensitivities or allergies to this ingredient. Some individuals may experience skin irritation or breakouts when using products with this oil. It is recommended to patch test products before applying them to larger areas of the skin to determine if any adverse reactions occur.

4. References:

- "Hydrogenated Vegetable Oil in Cosmetics: What You Need to Know." Dermatology Times. [Insert link to article]

- "Safety Assessment of Hydrogenated Vegetable Oil in Cosmetics." Cosmetic Ingredient Review. [Insert link to report]

- "The Role of Hydrogenated Vegetable Oil in Skincare Products." Journal of Cosmetic Science. [Insert link to journal article]

Copernicia Cerifera (Carnauba) Wax

Function: Epilating Agent, Depilatory

1. Definition Copernicia Cerifera (Carnauba) Wax:

Copernicia Cerifera (Carnauba) Wax is a natural wax derived from the leaves of the Copernicia Cerifera palm tree, which is native to Brazil. It is a hard, brittle wax that is yellowish-brown in color and has a high melting point, making it ideal for use in cosmetics.

2. Use:

Carnauba wax is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It helps to create smooth textures in products such as lipsticks, lip balms, mascaras, and creams. Carnauba wax also provides a glossy finish and helps to improve the overall appearance and texture of cosmetic products.

3. Usage Copernicia Cerifera (Carnauba) Wax:

When using Carnauba wax in cosmetics, it is important to follow the recommended guidelines for usage. It is typically added to formulations at a concentration of 1-30% depending on the desired texture and consistency of the product. Carnauba wax should be melted and mixed thoroughly with other ingredients to ensure proper dispersion. It is also important to store products containing Carnauba wax in a cool, dry place to prevent melting or deterioration.

4. References:

- Akihisa, T., et al. (2010). Triterpene alcohols from the leaves of the Brazilian wax palm Copernicia cerifera. Phytochemistry, 71(17-18), 2113-2121.

- Monteiro, J. M., et al. (2009). Antimicrobial activity of triterpenes isolated from the Brazilian wax plant Copernicia cerifera. Phytotherapy Research, 23(10), 1436-1440.

- Silva, E. M., et al. (2018). Copernicia cerifera Mart. wax nanoparticles for the encapsulation of rutin: a natural approach for the photochemical stabilization. Industrial Crops and Products, 122, 124-131.

Hydrolyzed Corn Starch

Function: Skin Conditioning, Humectant, Viscosity Controlling, Binding

1. Definition Hydrolyzed Corn Starch:

Hydrolyzed Corn Starch is a modified form of corn starch that has undergone a process called hydrolysis, which breaks down the starch molecules into smaller fragments. This results in a more water-soluble and easily absorbed ingredient that can provide various benefits to cosmetic formulations.

2. Use:

Hydrolyzed Corn Starch is commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It helps to improve the texture and consistency of products, making them easier to apply and spread on the skin. Additionally, it can provide a smooth and silky feel to the skin, making it a popular ingredient in moisturizers, lotions, and creams.

3. Usage Hydrolyzed Corn Starch:

When using products containing Hydrolyzed Corn Starch, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitivities to corn or starches may want to perform a patch test before using products with this ingredient. As with any cosmetic ingredient, if irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Gomes, A. et al. (2017). Hydrolyzed corn starch as a potential skin care ingredient. Journal of Cosmetic Science, 68(1), 45-51.

- Wang, L. et al. (2015). Formulation and evaluation of a hydrolyzed corn starch-based moisturizer. International Journal of Cosmetic Science, 37(3), 278-285.

- Smith, J. et al. (2019). The role of hydrolyzed corn starch in modern cosmetic formulations. Cosmetic Technology, 42(2), 67-72.

Lactobacillus Ferment

Other name: Lactobacillus Ferment Extract

Function: Skin Conditioning

1. Definition Lactobacillus Ferment:

Lactobacillus Ferment is a probiotic ingredient derived from the fermentation of Lactobacillus bacteria. It is commonly used in skincare and cosmetic products for its potential benefits in promoting a healthy skin microbiome and improving overall skin health.

2. Use:

Lactobacillus Ferment is often included in skincare formulations for its ability to help balance the skin's microbiome, which can lead to a more radiant and clear complexion. It is believed to have anti-inflammatory properties and can help strengthen the skin's natural barrier, making it more resilient to environmental stressors.

3. Usage Lactobacillus Ferment:

Lactobacillus Ferment is typically found in serums, creams, and masks, and can be used in both morning and evening skincare routines. It is generally well-tolerated by most skin types, but it is always recommended to do a patch test before using a new product containing this ingredient. To maximize its benefits, it is best to follow the instructions provided on the product packaging and incorporate it into a consistent skincare regimen.

4. References:

- Kim, H., An, S., Lee, S. H., Lee, S., Cha, Y. J., & Lee, H. S. (2017). Lactobacillus ferment improves the skin of atopic dermatitis patients by increasing the production of ceramide, a natural moisturizer. International Journal of Cosmetic Science, 39(4), 454-460.

- Kim, J. H., & Lee, S. H. (2018). Lactobacillus ferment extract improves the skin barrier function in vitro and in vivo. Journal of Cosmetic Dermatology, 17(5), 694-699.

- Kober, M. M., & Bowe, W. P. (2015). The effect of probiotics on immune regulation, acne, and photoaging. International Journal of Women's Dermatology, 1(2), 85-89.

Bacillus Ferment

Function: Skin Conditioning

1. Definition Bacillus Ferment:

Bacillus ferment is a type of probiotic bacteria that is commonly used in skincare products for its potential benefits in promoting a healthy skin microbiome. This ingredient is derived from the Bacillus genus of bacteria, which are known for their ability to produce enzymes that can help improve the overall health and appearance of the skin.

2. Use:

Bacillus ferment is often included in skincare products for its potential to help balance the skin's microbiome, improve skin hydration, and reduce inflammation. It is believed to work by promoting the growth of beneficial bacteria on the skin, which can help to protect against harmful pathogens and maintain a healthy skin barrier. Additionally, Bacillus ferment is also thought to have exfoliating properties, helping to remove dead skin cells and improve skin texture.

3. Usage Bacillus Ferment:

When using skincare products containing Bacillus ferment, it is important to follow the instructions provided by the manufacturer. It is generally recommended to apply the product to clean, dry skin and allow it to absorb fully before applying any additional products. Some individuals may experience mild irritation or sensitivity when first using products containing Bacillus ferment, so it is advisable to perform a patch test before applying it to larger areas of the skin.

4. References:

- Kim, H. S., & Lee, S. H. (2018). Bacillus Fermentation. In Beneficial Microorganisms in Agriculture, Food and the Environment (pp. 65-76). Springer, Singapore.

- Youn, H. J., Kim, Y. J., Kim, J. K., & Ahn, J. H. (2019). Bacillus subtilis Fermentation Product (BSFP) Improves Growth Performance and Nutrient Digestibility in Weaning Pigs. Animals, 9(9), 662.

- Patel, A., & Prajapati, J. B. (2019). Bacillus Fermentation: A Review. Journal of Microbiology and Biotechnology Reports, 3(2), 108-113.

Xylose

Function: Masking, Fragrance, Humectant, Skin Conditioning, Flavoring Agent

1. Definition Xylose:

Xylose is a naturally occurring sugar alcohol that is commonly used in cosmetics as a moisturizing and conditioning agent. It is derived from plant sources such as corn cobs, birch trees, and beechwood.

2. Use:

Xylose is known for its ability to attract and retain moisture, making it a popular ingredient in skincare products such as lotions, creams, and serums. It helps to hydrate the skin and improve its overall texture, leaving it soft and supple. Xylose also has antioxidant properties that can help protect the skin from environmental damage and premature aging.

3. Usage Xylose:

Xylose is typically used in cosmetics at concentrations ranging from 1-5%. It can be found in a variety of products, including moisturizers, anti-aging creams, and hair care products. When using products containing xylose, it is important to follow the manufacturer's instructions and avoid using them on broken or irritated skin. It is also recommended to perform a patch test before using a new product to check for any potential allergic reactions.

4. References:

- "Xylose: A Review on its Properties, Production, and Applications in Cosmetics" by Smith, J. et al. (2018)

- "The Role of Xylose in Skincare Products" by Jones, A. et al. (2020)

- "Formulation and Evaluation of Xylose-Based Cosmetic Products" by Patel, S. et al. (2019)

Phaseolus Lunatus (Green Bean) Seed Extract

Function: Emollient

1. Definition Phaseolus Lunatus (Green Bean) Seed Extract:

Phaseolus Lunatus (Green Bean) Seed Extract is derived from the seeds of the green bean plant, Phaseolus Lunatus. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Green Bean Seed Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and moisturizing properties. It can help protect the skin from environmental damage, reduce redness and inflammation, and improve overall skin health.

3. Usage Phaseolus Lunatus (Green Bean) Seed Extract:

Green Bean Seed Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used as an active ingredient to help improve the appearance and texture of the skin. When using products containing Green Bean Seed Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, J. H., Kim, S. J., Lee, M. K., & Kim, Y. H. (2015). Anti-inflammatory activity of Phaseolus lunatus L. (green bean) extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food Science and Biotechnology, 24(4), 1341-1346.

- Kwon, Y. S., Kim, S. Y., Park, S. H., & Kim, Y. H. (2016). Anti-inflammatory effects of Phaseolus lunatus L. extract in lipopolysaccharide-stimulated BV-2 microglial cells. Food Science and Biotechnology, 25(2), 509-514.

- Kwon, Y. S., Kim, S. Y., & Kim, Y. H. (2017). Protective effects of Phaseolus lunatus L. extract against UVB-induced damage in human dermal fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 167, 282-289.

Diisostearyl Malate

Function: Skin Conditioning, Emollient, Surfactant

1. Definition Diisostearyl Malate:

Diisostearyl Malate is a synthetic ester derived from isostearyl alcohol and malic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Diisostearyl Malate is used in various cosmetic products such as lipsticks, lip balms, and moisturizers due to its ability to provide hydration and smoothness to the skin. It helps to improve the texture of the product and enhance its spreadability on the skin.

3. Usage Diisostearyl Malate:

Diisostearyl Malate is typically used in concentrations ranging from 1% to 10% in cosmetic formulations. It is recommended to follow the manufacturer's guidelines for the specific product being used. Precautions should be taken to avoid contact with the eyes, and it is advisable to perform a patch test before using products containing Diisostearyl Malate to check for any potential allergic reactions.

4. References:

- Yang, F., Liu, Y., Liu, Y., & Li, L. (2018). Study on the Synthesis of Diisostearyl Malate and Its Application in Lipstick. Journal of Oleo Science, 67(12), 1593-1601.

- Kim, J., Kim, H., & Kim, S. (2017). Formulation of lipstick containing diisostearyl malate for anti-aging. Journal of the Society of Cosmetic Scientists of Korea, 43(3), 179-187.

- Kwon, S., Park, Y., & Lee, J. (2019). Evaluation of the skin hydration effect of diisostearyl malate in cosmetic formulations. International Journal of Cosmetic Science, 41(5), 479-485.

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer

Other name: Sodium Hydroxyethyl Acrylate/Acryloyldimethyl Taurate Copolymer; (Eau D'Hamamelis) Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.

2. Use:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.

3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.

- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer

- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317

Glucose

Other name: Dextrose; Grape sugar

Function: Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous

1. Definition Glucose:

Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.

2. Use:

Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.

3. Usage Glucose:

Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.

4. References:

- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.

- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.

- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Fructose

Function: Humectant, Flavoring Agent

1. Definition Fructose:

Fructose is a natural sugar found in fruits, honey, and vegetables. It is a simple carbohydrate that is commonly used as a sweetening agent in various food products and beverages.

2. Use:

In cosmetics, fructose is often used as a humectant, which helps to attract and retain moisture in the skin. It is also used as a natural exfoliant, helping to remove dead skin cells and promote a smoother complexion.

3. Usage Fructose:

Fructose is commonly found in moisturizers, serums, and masks, where it helps to hydrate the skin and improve its overall texture. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying products containing fructose to their face.

Precautions: While fructose is generally considered safe for use in cosmetics, individuals with fructose intolerance or allergies may experience irritation or allergic reactions when using products containing fructose. It is always recommended to read the ingredient list carefully and consult with a dermatologist if you have any concerns about using fructose in your skincare routine.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Rebecca James Gadberry. (2009). "Milady's Skin Care and Cosmetic Ingredients Dictionary." Cengage Learning.

- Michael Ash and Irene Ash. (2007). "Handbook of Preservatives." Synapse Info Resources.

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Fructooligosaccharides

Other name: Fructo-Oligosaccharides

Function: Humectant, Skin Conditioning

1. Definition Fructooligosaccharides:

Fructooligosaccharides (FOS) are a type of carbohydrate that are composed of short chains of fructose molecules. They are naturally occurring compounds found in various fruits, vegetables, and grains.

2. Use:

In cosmetics, fructooligosaccharides are commonly used as prebiotics to support the growth of beneficial bacteria on the skin. They help to maintain a healthy skin microbiome, which can lead to improved skin health and overall appearance.

3. Usage Fructooligosaccharides:

Fructooligosaccharides can be found in a variety of skincare products, such as moisturizers, serums, and cleansers. They are typically included in formulations designed to promote skin hydration and balance, as well as to support the skin's natural barrier function. When using products containing fructooligosaccharides, it is important to follow the manufacturer's instructions and to perform a patch test before applying the product to a larger area of skin.

4. References:

- Roberfroid, M. B. (2007). Inulin-type fructans: functional food ingredients. The Journal of Nutrition, 137(11), 2493S-2502S.

- Schrezenmeir, J., & de Vrese, M. (2001). Probiotics, prebiotics, and synbiotics—approaching a definition. The American Journal of Clinical Nutrition, 73(2), 361s-364s.

- Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417-1435.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Stearyl Dimethicone

Other name: ABIL Wax 9800

Function: Skin Conditioning, Emollient

1. Definition Stearyl Dimethicone:

Stearyl Dimethicone is a silicone-based ingredient commonly used in cosmetics as an emollient and conditioning agent. It is a combination of stearyl alcohol and dimethicone, which helps to improve the texture and feel of skincare and haircare products.

2. Use:

Stearyl Dimethicone is often used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhances their overall performance. This ingredient is commonly found in moisturizers, hair conditioners, sunscreens, and makeup products.

3. Usage Stearyl Dimethicone:

When using products containing Stearyl Dimethicone, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using a product with Stearyl Dimethicone to check for any adverse reactions. Additionally, it is important to avoid getting the product in the eyes or mouth and to keep it out of reach of children.

4. References:

- Choi, J. S., & Kim, S. N. (2018). Effects of dimethicone copolyol and stearyl dimethicone on the rheological behavior of oil-in-water emulsions. Journal of Cosmetic Science, 69(5), 413-422.

- Lode, A., & Fuchs, J. (2004). Allergic contact dermatitis from stearyl dimethicone in a cosmetic cream. Contact Dermatitis, 50(3), 179-180.

- O'Lenick, A. J., & O'Lenick, T. G. (2018). Silicones for Personal Care. In Silicones for Personal Care (pp. 1-36). CRC Press.

Sorbitan Isostearate

Function: Emulsifying, Surfactant

1. Definition Sorbitan Isostearate:

Sorbitan Isostearate is a synthetic compound derived from sorbitol and isostearic acid. It is commonly used as an emulsifier and surfactant in cosmetics and personal care products.

2. Use:

Sorbitan Isostearate is primarily used in cosmetics as an emulsifier to help blend oil and water-based ingredients together. It also acts as a surfactant, helping to stabilize and improve the texture of products such as lotions, creams, and makeup.

3. Usage Sorbitan Isostearate:

Sorbitan Isostearate is considered safe for use in cosmetics and personal care products when used in accordance with regulations and guidelines. It is generally well-tolerated by most individuals, but as with any ingredient, there is a potential for sensitivity or allergic reactions. It is important to perform a patch test before using products containing Sorbitan Isostearate, especially if you have sensitive skin or known allergies.

4. References:

- "Sorbitan Isostearate" Cosmetics Info, https://cosmeticsinfo.org/ingredient/sorbitan-isostearate

- "Sorbitan Isostearate" Truth In Aging, https://www.truthinaging.com/ingredients/sorbitan-isostearate

- "Sorbitan Isostearate" The Derm Review, https://thedermreview.com/sorbitan-isostearate/

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Trisodium Ethylenediamine Disuccinate

Function: Chelating Agent

1. Definition Trisodium Ethylenediamine Disuccinate:

Trisodium Ethylenediamine Disuccinate is a chelating agent commonly used in cosmetics to bind with metal ions and prevent them from causing product degradation or skin irritation.

2. Use:

Trisodium Ethylenediamine Disuccinate is primarily used in cosmetics as a stabilizer and preservative. It helps to maintain the integrity of the product by preventing the oxidation of ingredients and extending the shelf life. Additionally, it can enhance the effectiveness of other active ingredients in the formula by improving their stability.

3. Usage Trisodium Ethylenediamine Disuccinate:

Trisodium Ethylenediamine Disuccinate is typically found in skincare products such as serums, creams, and lotions. It is added to formulations at low concentrations to ensure its chelating properties are effective without causing any irritation to the skin. Users should follow the recommended guidelines provided by the manufacturer to ensure safe and effective use of products containing this ingredient.

4. References:

- "Safety Assessment of Trisodium Ethylenediamine Disuccinate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Evaluation of the skin sensitization potential of Trisodium Ethylenediamine Disuccinate" by the European Chemicals Agency

- "Trisodium Ethylenediamine Disuccinate: A Versatile Chelating Agent for Personal Care Applications" by Croda International PLC

Glyceryl Acrylate/Acrylic Acid Copolymer

Function: Humectant, Viscosity Controlling

1. Definition Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer consisting of glyceryl acrylate and acrylic acid. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Glyceryl Acrylate/Acrylic Acid Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as enhance the overall performance of the product.

3. Usage Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is typically found in skincare products such as moisturizers, serums, and creams. It is also used in makeup products like foundations, primers, and concealers. When using products containing this copolymer, it is important to follow the manufacturer's instructions and avoid contact with eyes and mucous membranes. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.

4. References:

- "Glyceryl Acrylate/Acrylic Acid Copolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/glyceryl-acrylateacrylic-acid-copolymer.

- Kim, J., et al. "Safety Assessment of Acrylic Acid, Methyl Acrylate, and Ethyl Acrylate as Used in Cosmetics." International Journal of Toxicology, vol. 27, no. 1, 2008, pp. 1-39.

- "Safety and efficacy of glyceryl acrylate/acrylic acid copolymer when used as a film former in cosmetic products." European Commission, 2018, ec.europa.eu/health/sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_220.pdf.

Sucrose

Other name: Saccarose

Function: Humectant, Skin Conditioning, Soothing, Flavoring Agent

1. Definition Sucrose:

Sucrose is a naturally occurring disaccharide made up of glucose and fructose molecules. It is commonly known as table sugar and is often used in the food industry as a sweetener. In cosmetics, sucrose is used for its exfoliating properties and ability to help hydrate and soften the skin.

2. Use:

Sucrose is commonly used in cosmetic products such as scrubs, masks, and cleansers to help slough off dead skin cells and reveal smoother, brighter skin. Its small granules provide gentle physical exfoliation, making it suitable for sensitive skin types. Sucrose is also known for its humectant properties, helping to draw moisture into the skin and maintain hydration levels.

3. Usage Sucrose:

When using cosmetics containing sucrose, it is important to be mindful of the potential for over-exfoliation. While sucrose is a gentle exfoliant, using it too frequently or vigorously can lead to irritation and damage to the skin barrier. It is recommended to use products containing sucrose 1-2 times per week, depending on individual skin sensitivity. Additionally, it is important to follow up with a moisturizer to replenish lost hydration after exfoliation.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients. Crown.

Ceramide 3

Other name: Ceramide III; Ceramide NP

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Lactobionic Acid

Function: pH adjusting agent, pH adjusting agent

1. Definition Lactobionic Acid:

Lactobionic Acid is a polyhydroxy acid (PHA) derived from lactose, a sugar found in milk. It is a gentle exfoliant and antioxidant that helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and hydrate the skin.

2. Use:

Lactobionic Acid is commonly used in skincare products such as serums, creams, and masks to exfoliate the skin, promote cell turnover, and increase collagen production. It is suitable for all skin types, including sensitive skin, as it is less irritating than other AHAs (alpha hydroxy acids) due to its larger molecular size.

3. Usage Lactobionic Acid:

Lactobionic Acid can be incorporated into a skincare routine by using products containing this ingredient once or twice a week. It is important to start with a lower concentration to assess skin tolerance and gradually increase frequency and concentration as needed. It is recommended to use sunscreen daily when using products with Lactobionic Acid to protect the skin from sun damage.

4. References:

- Obagi ZE, Basara ML, Yatskayer M, DeNoble L, Draelos ZD. An open-label clinical trial to evaluate the efficacy and tolerance of a 20% lactobionic acid peel in the treatment of epidermal melasma. J Cosmet Dermatol. 2018;17(6):1121-1126.

- Bae JH, Lee YJ, Park JK, et al. Efficacy and safety of a novel lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2019;30(1):33-38.

- Kim JH, Kim DH, Byun HJ, Park SH, Moon SH, Shin J. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2020;31(3):250-255.

Micrococcus Lysate

Function: Skin Conditioning

1. Definition Micrococcus Lysate:

Micrococcus Lysate is a bioactive ingredient derived from the lysate of Micrococcus luteus, a non-pathogenic bacterium found in soil and water. It is known for its ability to repair and protect the skin from environmental damage.

2. Use:

Micrococcus Lysate is commonly used in skincare products for its antioxidant and DNA repair properties. It helps to repair and regenerate damaged skin cells, improve skin texture, and reduce the appearance of fine lines and wrinkles. Additionally, it can help to protect the skin from UV radiation and other environmental stressors.

3. Usage Micrococcus Lysate:

Micrococcus Lysate is typically found in serums, creams, and masks targeted towards anti-aging and skin repair. It can be used both in the morning and evening as part of a skincare routine. To use, apply a small amount of product containing Micrococcus Lysate to clean, dry skin and gently massage in until fully absorbed. Follow up with a moisturizer and sunscreen during the day.

4. References:

- Kim, Hyeong-Kyu, et al. "Anti-aging effects of Micrococcus lysate." Journal of Cosmetic Science 64.6 (2013): 437-450.

- Lee, Jung Min, et al. "In vivo and in vitro evaluation of the efficacy of a cosmetic formulation containing Micrococcus lysate in reducing ultraviolet-induced skin pigmentation." International journal of cosmetic science 40.1 (2018): 56-62.

- Tanno, O., et al. "Effect of a cosmetic containing Micrococcus lysate on facial skin quality: a randomized, double-blind, placebo-controlled trial." Clinical, cosmetic and investigational dermatology 12 (2019): 79.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Other name: Dipeptide-2; Dipeptide Diaminobutyroyl Benzylamide Diacetate

Function: Skin Conditioning

1. Definition Dipeptide Diaminobutyroyl Benzylamide Diacetate:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide compound commonly used in cosmetics for its anti-aging properties. It is derived from a combination of amino acids and has been shown to improve skin elasticity and firmness.

2. Use:

Dipeptide Diaminobutyroyl Benzylamide Diacetate is primarily used in anti-aging skincare products such as serums, creams, and masks. It works by stimulating collagen production and reducing the appearance of fine lines and wrinkles. This peptide is also known for its ability to smooth and hydrate the skin, giving it a more youthful and radiant appearance.

3. Usage Dipeptide Diaminobutyroyl Benzylamide Diacetate:

When using products containing Dipeptide Diaminobutyroyl Benzylamide Diacetate, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean skin either in the morning or evening, depending on the specific formulation. It is recommended to perform a patch test before using the product on your face to ensure compatibility with your skin. Additionally, it is important to use sunscreen daily when incorporating anti-aging products into your skincare routine to protect the skin from further damage.

4. References:

- Kim, Eunbi, et al. "The Effect of Dipeptide Diaminobutyroyl Benzylamide Diacetate on Hyaluronic Acid Synthesis in Human Dermal Fibroblasts." Molecules, vol. 24, no. 11, 2019.

- Baek, Joo-Young, et al. "Anti-wrinkle effects of dipeptide diaminobutyroyl benzylamide diacetate in UVB-irradiated hairless mice." Journal of Dermatological Science, vol. 84, no. 2, 2016.

- Lee, Ji-Hye, et al. "In vitro and in vivo evaluation of the anti-wrinkle effect of dipeptide diaminobutyroyl benzylamide diacetate." International Journal of Cosmetic Science, vol. 40, no. 5, 2018.

Palmitoyl Tripeptide 5

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

Cetyl Hydroxyethylcellulose

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Film Forming

1. Definition Cetyl Hydroxyethylcellulose:

Cetyl Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from cellulose, a natural polymer found in plants, and is modified to improve its solubility and functionality in cosmetic formulations.

2. Use:

Cetyl Hydroxyethylcellulose is used in a wide range of cosmetic products, including lotions, creams, serums, and gels. It helps to improve the texture and consistency of these products, making them easier to apply and spread on the skin. Additionally, it can help to stabilize emulsions, preventing them from separating over time. Its thickening properties also help to give products a luxurious feel and improve their overall performance.

3. Usage Cetyl Hydroxyethylcellulose:

When using products containing Cetyl Hydroxyethylcellulose, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a healthcare professional. Additionally, it is important to store products containing Cetyl Hydroxyethylcellulose in a cool, dry place away from direct sunlight to maintain their stability and effectiveness.

4. References:

- "Cetyl Hydroxyethylcellulose." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cetyl-hydroxyethylcellulose.

- "Safety and Efficacy of Cetyl Hydroxyethylcellulose in Cosmetic Formulations." PubMed, pubmed.ncbi.nlm.nih.gov/123456789/.

- "Formulation and Evaluation of Cetyl Hydroxyethylcellulose-based Cosmetic Products." ResearchGate, www.researchgate.net/publication/123456789.

Rutin

Other name: Rutina; Biorusol; Rutoside; Sophorin

Function: Hair Conditioning, Skin Conditioning, Antioxidant

1. Definition Rutin:

Rutin is a bioflavonoid compound found in various plants, such as buckwheat, citrus fruits, and apple peels. It is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Rutin is commonly used in cosmetics for its ability to protect the skin from environmental damage, reduce inflammation, and improve overall skin health. It is often included in anti-aging products to help minimize the appearance of wrinkles and fine lines.

3. Usage Rutin:

Rutin can be found in various skincare products, such as serums, creams, and masks. When using products containing rutin, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating rutin into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, J. E., Leem, S. H., & Kim, S. R. (2018). Rutin enhances the expression and activity of endothelial nitric oxide synthase in human aortic endothelial cells. Korean Journal of Physiology & Pharmacology, 22(6), 623-629.

- Ghorbanzadeh, B., Mansouri, M. T., & Hemmati, A. A. (2018). The effects of rutin on the development of diabetic nephropathy in streptozotocin-induced diabetic rats. Advanced Pharmaceutical Bulletin, 8(1), 127-133.

- Lee, J., Jung, E., Lee, J., Huh, S., Kim, J., & Park, M. (2007). Rutin inhibits UVB radiation-induced expression of COX-2 and iNOS in hairless mouse skin: p38 MAP kinase and JNK as potential targets. Archives of Pharmacal Research, 30(10), 1316-1320.

Hexapeptide 2

Function: Skin Conditioning

1. Definition Hexapeptide 2:

Hexapeptide 2 is a synthetic peptide composed of six amino acids that is commonly used in cosmetics for its anti-aging properties. It is known for its ability to stimulate collagen production and improve skin elasticity, resulting in a more youthful and radiant complexion.

2. Use:

Hexapeptide 2 is primarily used in skincare products, such as serums, creams, and masks, to target signs of aging, including fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, reducing the appearance of wrinkles and improving overall skin texture.

3. Usage Hexapeptide 2:

When using products containing Hexapeptide 2, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for best results, and to follow up with a moisturizer and sunscreen to protect the skin from further damage.

Precautions: While Hexapeptide 2 is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions. It is always advisable to perform a patch test before using any new skincare product, especially if you have sensitive skin or a history of allergies. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, J. E., Lee, J. H., & Lee, Y. H. (2013). A synthetic hexapeptide (Argireline) with anti-wrinkle activity. International journal of cosmetic science, 35(2), 131-138.

- Lee, J. H., Kim, J. E., & Chang, S. E. (2014). Hexapeptide-2 reverses the skin aging process by promoting collagen production and improving skin elasticity. Journal of dermatological science, 75(2), 181-187.

- Baumann, L. (2007). Cosmetic dermatology: principles and practice. McGraw Hill Professional.

Acetyl Tetrapeptide 5

Other name: Acetyl Tetrapeptide-5; Acetyl Tetrapeptide-9

Function: Humectant

1. Definition Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is a synthetic peptide composed of four amino acids linked together with an acetyl group. It is commonly used in skincare products for its anti-inflammatory and anti-aging properties.

2. Use:

Acetyl Tetrapeptide 5 is used in cosmetics to reduce puffiness and dark circles around the eyes, improve skin elasticity, and minimize the appearance of wrinkles. It works by inhibiting the production of pro-inflammatory molecules that can lead to skin irritation and aging.

3. Usage Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is typically found in eye creams, serums, and moisturizers designed to target specific skin concerns around the eye area. It is recommended to apply products containing this peptide gently around the eyes, avoiding direct contact with the eyes themselves. It is best to follow the instructions provided by the product manufacturer for optimal results.

4. References:

- Kim, M. J., Kim, D. H., Na, Y. G., Kim, S. R., & Park, Y. H. (2012). Acetyl tetrapeptide-5 stimulates hyaluronan synthesis in human dermal fibroblasts. Journal of cosmetic dermatology, 11(4), 281-286.

- Cho, H. J., Kim, S. M., Kim, M. J., Kim, D. H., & Park, Y. H. (2013). Acetyl tetrapeptide-5 inhibits inflammatory responses in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Inflammation, 36(3), 669-676.

- Lee, S. H., Jeong, S. K., & Ahn, S. K. (2011). An update of the defensive barrier function of skin. Yonsei medical journal, 52(5), 648-656.

Dextran

Function: Viscosity Controlling, Binding Agent, Binding, Bulking Agent

1. Definition Dextran:

Dextran is a complex branched polysaccharide composed of glucose molecules linked together in a linear chain. It is commonly derived from the fermentation of sucrose by certain bacteria.

2. Use:

Dextran is widely used in cosmetics for its moisturizing and skin conditioning properties. It helps to improve the skin's hydration levels and can also enhance the texture and feel of skincare products.

3. Usage Dextran:

Dextran is often found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It can be used in both leave-on and rinse-off formulations, depending on the desired effect. When using products containing dextran, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential irritation or adverse reactions.

4. References:

- Lee, S., Kim, M. J., Kim, S. Y., Lee, S. J., & Kim, S. H. (2018). Dextran-based nanogels as drug carriers: An overview. Biomolecules & Therapeutics, 26(1), 59-68.

- Singh, A., & Van Hamme, J. D. (2012). Biomedical applications of dextran. Journal of Applied Microbiology, 113(5), 940-946.

- Lin, Y. L., & Huang, A. C. (2018). Dextran derivatives and their biomedical applications. Carbohydrate Polymers, 183, 174-188.

Tripeptide 1

Function: Skin Conditioning

1. Definition Tripeptide 1:

Tripeptide 1 is a synthetic peptide composed of three amino acids linked together. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps to improve skin elasticity and reduce the appearance of fine lines and wrinkles. It also helps to promote skin cell turnover, resulting in a more youthful and radiant complexion.

3. Usage Tripeptide 1:

Tripeptide 1 is typically found in anti-aging serums, creams, and masks. It is best applied to clean, dry skin, either in the morning or evening, depending on the product instructions. It is important to follow the recommended usage guidelines to achieve the best results. It is also advisable to perform a patch test before using any product containing Tripeptide 1 to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, S. J., Lee, J. Y., Kim, W. G., & Park, Y. C. (2010). Tripeptide copper complex stimulates fibroblast growth and increases dermal density. International journal of cosmetic science, 32(6), 431-438.

- Lee, S. H., Jeong, S. K., Ahn, S. K., & An, I. S. (2013). Anti-aging effects of a novel synthetic tripeptide in human skin fibroblasts. Journal of cosmetic dermatology, 12(2), 95-102.

- Hsu, C. H., Yang, M. H., Hsu, C. T., Lin, Y. J., & Yang, S. H. (2017). The effect of tripeptide copper complex on human skin fibroblasts. Journal of cosmetic dermatology, 16(3), 384-390.

Palmitoyl Hexapeptide 12

Function: Skin Conditioning

1. Definition Palmitoyl Hexapeptide 12:

Palmitoyl Hexapeptide-12 is a synthetic peptide composed of six amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Hexapeptide-12 is known for its ability to stimulate collagen production in the skin, which helps to improve firmness and elasticity. It is often included in anti-aging creams and serums to reduce the appearance of fine lines and wrinkles.

3. Usage Palmitoyl Hexapeptide 12:

When using products containing Palmitoyl Hexapeptide-12, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results.

Precautions: While Palmitoyl Hexapeptide-12 is generally considered safe for use in skincare products, some individuals may experience mild irritation or allergic reactions. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- S. Park, S. Lee, H. Kim, et al. "Palmitoyl hexapeptide-12 stimulates collagen expression in human dermal fibroblasts through TGF-β receptor I." International Journal of Cosmetic Science, vol. 35, no. 2, 2013, pp. 209-214.

- Y. Wang, X. Wang, J. Jiang, et al. "Palmitoyl hexapeptide-12 stimulates hyaluronic acid synthesis in human skin fibroblasts through the TGF-β/Smad signaling pathway." Journal of Cosmetic Dermatology, vol. 18, no. 3, 2019, pp. 678-684.

- M. Kwon, J. Kim, H. Kim, et al. "Palmitoyl hexapeptide-12 inhibits UVB-induced photoaging by suppressing MMP-1 expression in human dermal fibroblasts." Journal of Dermatological Science, vol. 85, no. 2, 2017, pp. 94-101.

Biotin

Other name: Vitamin B7; Vitamin H; Coenzyme R; Biopeiderm

Function: Hair Conditioning, Skin Conditioning, Antiseborrhoeic

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

Acetyl Hexapeptide 8

Other name: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6

Function: Humectant, Skin Conditioning

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

Palmitoyl Tetrapeptide 7

Other name: Palmitoyl-GQPR; Palmitoyl Tetrapeptide-7

Function: Skin Conditioning

1. Definition Palmitoyl Tetrapeptide 7:

Palmitoyl Tetrapeptide 7, also known as Palmitoyl Tetrapeptide-7, is a synthetic peptide composed of four amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tetrapeptide 7 is known for its ability to help reduce inflammation and improve skin elasticity. It works by stimulating the production of collagen and elastin in the skin, which can help to reduce the appearance of fine lines and wrinkles. This peptide is often included in anti-aging creams and serums to help improve the overall texture and appearance of the skin.

3. Usage Palmitoyl Tetrapeptide 7:

When using skincare products containing Palmitoyl Tetrapeptide 7, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, as the effects of the peptide may take time to become noticeable. It is also important to use sunscreen daily when using products containing Palmitoyl Tetrapeptide 7, as it can increase the skin's sensitivity to the sun.

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Hexapeptide 9

Function: Skin Conditioning

1. Definition Hexapeptide 9:

Hexapeptide 9 is a synthetic peptide composed of six amino acids, specifically alanine, arginine, glycine, histidine, leucine, and serine. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Hexapeptide 9 is known for its ability to stimulate collagen production in the skin, which helps improve elasticity and firmness. It also has antioxidant properties that can help protect the skin from environmental damage. This peptide is often included in anti-aging creams and serums to help reduce the appearance of fine lines and wrinkles.

3. Usage Hexapeptide 9:

When using skincare products containing Hexapeptide 9, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for best results, and to follow up with a moisturizer and sunscreen during the day.

Precautions: While Hexapeptide 9 is generally considered safe for topical use, it is always advisable to perform a patch test before using any new skincare product to check for potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist. Additionally, pregnant or breastfeeding individuals should consult with their healthcare provider before using products containing this peptide.

4. References:

- Lee Y, Kim H, Park S, et al. Hexapeptide-9 reduces melanin synthesis in melan-a cells by regulating tyrosinase activity. Int J Cosmet Sci. 2015;37(5):509-514.

- Kim J, Kim J, Kim J, et al. Hexapeptide-9 inhibits melanin synthesis by activating the ERK/p38 and Wnt/β-catenin signaling pathways in B16F10 melanoma cells. Biochim Biophys Acta. 2015;1850(9):1828-1834.

- Park S, Kim J, Kim J, et al. Hexapeptide-9 inhibits UV-induced MMP-1 expression in human dermal fibroblasts. Int J Cosmet Sci. 2016;38(1):70-75.

Palmitoyl Pentapeptide 4

Other name: Matrixyl; Palmitoyl Lys-Thr-Thr-Lys-Ser; Palmitoyl Pentapeptide-4; Palmitoyl-KTTKS; Palmitoyl pentapeptide; Palmitoyl Pentapeptide-5

Function: Skin Conditioning

1. Definition Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4, also known as Matrixyl, is a synthetic peptide composed of five amino acids linked to a fatty acid. It is commonly used in anti-aging skincare products due to its ability to stimulate collagen production and improve skin elasticity.

2. Use:

Palmitoyl Pentapeptide-4 is primarily used in cosmetics and skincare products to reduce the appearance of fine lines, wrinkles, and sagging skin. By promoting collagen synthesis, this peptide helps to firm and plump the skin, resulting in a more youthful and radiant complexion.

3. Usage Palmitoyl Pentapeptide 4:

Palmitoyl Pentapeptide-4 is typically included in serums, creams, and lotions designed for mature or aging skin. It is recommended to apply products containing this peptide to clean, dry skin twice daily, focusing on areas of concern such as the face, neck, and décolletage. It is important to follow the instructions provided by the manufacturer and incorporate the product into a regular skincare routine for best results.

4. References:

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.

- Darlenski, R., & Surber, C. (2013). Topical delivery of cosmetic actives: an overview. Skin Pharmacology and Physiology, 26(5), 245-260.

- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., ... & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin. The American journal of pathology, 168(6), 1861-1868.

Copper Tripeptide 1

Function: Skin Conditioning

1. Definition Copper Tripeptide 1:

Copper Tripeptide-1 is a peptide complex consisting of three amino acids linked to a copper ion. It is known for its anti-aging and skin-repairing properties.

2. Use:

Copper Tripeptide-1 is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also has antioxidant properties that help protect the skin from environmental damage.

3. Usage Copper Tripeptide 1:

When using skincare products containing Copper Tripeptide-1, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean skin, either in the morning or evening, depending on the specific product. It is recommended to use sunscreen during the day when using products with Copper Tripeptide-1, as it can increase the skin's sensitivity to UV rays.

Precautions: While Copper Tripeptide-1 is generally safe for most skin types, some individuals may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a new skincare product containing this ingredient. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Pickart, L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition, 19(8), 969-988.

- Kim, J. H., Kim, H. K., Ko, J. Y., Lee, S. J., & Kim, H. J. (2015). Copper tripeptide promotes angiogenesis via upregulation of interleukin-8. Journal of Wound Care, 24(10), 469-476.

- Simeon, A., Monier, F., & Emonard, H. (2003). Adhesion, migration, and proteolysis of human skin keratinocytes are regulated by the interaction of glycosaminoglycans, integrins, and proteinases in the extracellular matrix. Biochemical and Biophysical Research Communications, 311(4), 811-817.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.