Full ingredients list Clarins Multi-active Day Cream

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	B	Coco Caprylate/ Caprate (Skin Conditioning, Emollient)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Butyrospermum Parkii (Shea) Butter	Bad for oily skin Fungal Acne Trigger
1	B	Cetearyl Ethylhexanoate (Skin Conditioning, Emollient, Hair Conditioning)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1 3	A	Peg 100 Stearate (Surfactant)	Fungal Acne Trigger
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
2	B	Cetearyl Glucoside (Emulsifying, Surfactant)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin
1		Dipsacus Sylvestris Extract (Skin Conditioning)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1	A	Cellulose (Viscosity Controlling, Absorbent, Bulking Agent, Opacifying, Slip Modifier)
1 3		Titanium Dioxide (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin
1	A	Synthetic Fluorphlogopite (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Dimethiconol (Skin Conditioning, Emollient, Antifoaming Agent, Moisturising)	Silicone
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Tocopherol	Good for dry skin Anti Aging
1		Marrubium Vulgare Extract (Fragrance, Skin Conditioning, Soothing)
2	A	Tetrasodium Edta (Chelating Agent)
		Myrothamnus Flabellifolia Leaf/Stem Extract
1	B	Phenethyl Alcohol (Masking, Fragrance, Preservative)
		Furcellaria Lumbricalis Extract (Skin Conditioning)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	A	Sodium Citrate (Masking, pH adjusting agent, pH adjusting agent, Chelating)
1	A	Ascorbic Acid (Vitamin C) (Masking, pH adjusting agent, Skin Conditioning, Antioxidant, Flavoring Agent, Phadjuster)	Good for dry skin Anti Aging Brightening
1		Lactic Acid/Glycolic Acid Copolymer (Skin Conditioning)
		Lapsana Communis Flower/Leaf/Stem Extract (Skin Conditioning)
1		Sea Salt (Masking, Humectant, Viscosity Controlling, Abrasive, Bulking Agent)
3		CI 14700 (Cosmetic Colorant)
2		CI 17200 (Cosmetic Colorant)
		Heptapeptide-15 Palmitate (Skin Conditioning)
1	A	Polyvinyl Alcohol (Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Film Forming)
		Copper Palmitoyl Heptapeptide-14 (Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Coco Caprylate/ Caprate

Function: Skin Conditioning, Emollient

1. Definition Coco Caprylate/ Caprate:

Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.

2. Use:

Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.

3. Usage Coco Caprylate/ Caprate:

When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate

- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate

- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Butyrospermum Parkii (Shea) Butter

Function:

1. Definition Butyrospermum Parkii (Shea) Butter:

Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.

3. Usage Butyrospermum Parkii (Shea) Butter:

When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

Cetearyl Ethylhexanoate

Function: Skin Conditioning, Emollient, Hair Conditioning

1. Definition Cetearyl Ethylhexanoate:

Cetearyl Ethylhexanoate is a synthetic compound that belongs to the ester family. It is a combination of cetearyl alcohol and ethylhexanoic acid, commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cetearyl Ethylhexanoate is primarily used in skincare and haircare products as a moisturizer due to its emollient properties. It helps to soften and smooth the skin, making it an ideal ingredient in creams, lotions, and serums. Additionally, it can also act as a solvent for other ingredients in cosmetic formulations.

3. Usage Cetearyl Ethylhexanoate:

When using products containing Cetearyl Ethylhexanoate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical application, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is advisable to avoid contact with eyes and mucous membranes.

4. References:

- "Cetearyl Ethylhexanoate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cetearyl-ethylhexanoate.

- "Cetearyl Ethylhexanoate." Truth in Aging, www.truthinaging.com/ingredients/cetearyl-ethylhexanoate.

- "Cetearyl Ethylhexanoate." The Derm Review, www.thedermreview.com/cetearyl-ethylhexanoate/.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Peg 100 Stearate

Function: Surfactant

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Cetearyl Glucoside

Function: Emulsifying, Surfactant

1. Definition Cetearyl Glucoside:

Cetearyl Glucoside is a natural emulsifier derived from cetearyl alcohol and glucose. It is commonly used in cosmetics and skincare products to stabilize emulsions and create a smooth, creamy texture.

2. Use:

Cetearyl Glucoside is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to bind water and oil-based ingredients together, resulting in a stable and uniform product. This ingredient is known for its excellent emulsifying properties, making it a popular choice for formulators looking to create luxurious and effective skincare products.

3. Usage Cetearyl Glucoside:

When using products containing Cetearyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Cetearyl Glucoside" by CosmeticsInfo.org

- "Cetearyl Glucoside" by Truth in Aging

- "Cetearyl Glucoside in Cosmetics" by PubMed Central

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

Dipsacus Sylvestris Extract

Function: Skin Conditioning

1. Definition Dipsacus Sylvestris Extract:

Dipsacus Sylvestris Extract, also known as wild teasel extract, is derived from the plant Dipsacus sylvestris, which is native to Europe and Asia. This extract is commonly used in cosmetics for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipsacus Sylvestris Extract is often included in skincare products for its ability to help calm and soothe irritated skin. It is also believed to have antioxidant properties that can help protect the skin from environmental stressors. Additionally, this extract may help improve the overall appearance of the skin by promoting a more even tone and texture.

3. Usage Dipsacus Sylvestris Extract:

Dipsacus Sylvestris Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effect. When using products containing this extract, it is important to follow the manufacturer's instructions for application to ensure optimal results. As with any new skincare ingredient, it is recommended to perform a patch test before using products with Dipsacus Sylvestris Extract to check for any potential allergic reactions.

4. References:

- Lee, S. J., Kim, H. J., Lee, S. Y., Lee, J. H., Lee, J. H., & Kim, J. H. (2016). Anti-inflammatory effect of Dipsacus sylvestris extract in LPS-stimulated RAW 264.7 macrophages. Molecular Medicine Reports, 13(2), 1757-1764.

- Lee, J. H., Lee, S. Y., Kim, H. J., Lee, S. J., Kim, J. H., & Kim, Y. S. (2017). Antioxidant and anti-inflammatory activities of Dipsacus asper Wall. ex C.B. Clarke extract. Journal of Ethnopharmacology, 208, 87-95.

- Yang, E. J., Moon, J. Y., Kim, M. J., Kim, D. S., & Kim, C. S. (2011). Inhibitory effect of Dipsacus asperoides C.Y. Cheng et al. extract on matrix metalloproteinase-1 expression in ultraviolet-irradiated human dermal fibroblasts. Journal of Ethnopharmacology, 137(2), 427-433.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Cellulose

Other name: Hydroxycellulose; Pyrocellulose

Function: Viscosity Controlling, Absorbent, Bulking Agent, Opacifying, Slip Modifier

1. Definition Cellulose:

Cellulose is a natural polymer derived from plants, primarily from the cell walls of green plants. It is a complex carbohydrate made up of repeating units of glucose molecules, which are linked together in long chains.

2. Use:

In cosmetics, cellulose is commonly used as a thickening agent, emulsifier, stabilizer, and film-former. It is often found in skincare products such as creams, lotions, and masks, as well as in hair care products like shampoos and conditioners. Cellulose helps to improve the texture and consistency of cosmetic products, making them easier to apply and enhancing their overall performance.

3. Usage Cellulose:

When using cellulose in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper incorporation into formulations. Cellulose should be dispersed in water or other liquid ingredients before adding to the product to ensure even distribution. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing cellulose to the entire face or body.

4. References:

- R. M. Silverstein, G. C. Bassler, and T. C. Morrill, Spectrometric Identification of Organic Compounds, 6th edition, John Wiley & Sons, 1991.

- C. S. Marvel, J. A. McClelland, and R. A. Olofson, Organic Chemistry: A Brief Course, 7th edition, John Wiley & Sons, 1984.

- J. Clayden, N. Greeves, and S. Warren, Organic Chemistry, 2nd edition, Oxford University Press, 2012.

Titanium Dioxide

Other name: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase

Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

Synthetic Fluorphlogopite

Function: Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent

1. Definition Synthetic Fluorphlogopite:

Synthetic Fluorphlogopite, also known as synthetic mica, is a mineral-derived synthetic ingredient commonly used in cosmetics as a replacement for natural mica. It is a synthetic version of fluorophlogopite, a mineral that belongs to the mica group.

2. Use:

Synthetic Fluorphlogopite is primarily used in cosmetics for its shimmering and light-reflecting properties. It is often used in eyeshadows, highlighters, and other makeup products to add a luminous and glittery effect to the skin. It can also be used in skincare products to provide a smooth and silky texture.

3. Usage Synthetic Fluorphlogopite:

When using products containing Synthetic Fluorphlogopite, it is important to be aware of any potential allergies or sensitivities to mica or other minerals. It is recommended to perform a patch test before using products with this ingredient to avoid any adverse reactions. Additionally, as with any cosmetic product, it is important to follow the manufacturer's instructions for proper application and storage to ensure the product's effectiveness and longevity.

4. References:

- "Synthetic Fluorphlogopite" by Cosmetics Info

- "What Is Synthetic Fluorphlogopite?" by The Derm Review

- "Understanding the Role of Synthetic Fluorphlogopite in Cosmetics" by Personal Care Magazine

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Dimethiconol

Function: Skin Conditioning, Emollient, Antifoaming Agent, Moisturising

1. Definition Dimethiconol:

Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.

2. Use:

Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.

3. Usage Dimethiconol:

Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.

4. References:

- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.

- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.

- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Marrubium Vulgare Extract

Function: Fragrance, Skin Conditioning, Soothing

1. Definition Marrubium Vulgare Extract:

Marrubium Vulgare Extract is a natural ingredient derived from the Marrubium Vulgare plant, also known as white horehound. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and soothing properties.

2. Use:

Marrubium Vulgare Extract is used in cosmetics for its ability to calm and protect the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, its antioxidant properties can help protect the skin from environmental stressors and free radicals.

3. Usage Marrubium Vulgare Extract:

Marrubium Vulgare Extract can be found in various skincare products such as creams, serums, and masks. It is typically included in formulations at a concentration of around 1-5%. To use products containing Marrubium Vulgare Extract, simply apply them to clean skin as directed by the product instructions. It is important to patch test any new skincare product containing this ingredient to ensure compatibility with your skin.

4. References:

- Saeidnia, S., & Gohari, A. R. (2013). Pharmacological and therapeutic effects of Marrubium vulgare. Pharmacognosy reviews, 7(14), 188–194. https://doi.org/10.4103/0973-7847.120522

- Elansary, H. O., Szopa, A., & Kubica, P. (2019). Elicitation, an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories: The Case of Scrophularia striata L. and Marrubium vulgare L. Frontiers in pharmacology, 10, 746. https://doi.org/10.3389/fphar.2019.00746

- Lichius, J. J., Muth, C., & Weidner, C. (2019). Marrubium vulgare L. (Lamiaceae): A European Ethnomedicinal Plant with Substantial Pharmacological Studies. Journal of Ethnopharmacology, 245, 112177. https://doi.org/10.1016/j.jep.2019.112177

Tetrasodium Edta

Other name: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate

Function: Chelating Agent

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

Myrothamnus Flabellifolia Leaf/Stem Extract

Function:

1. Definition Myrothamnus Flabellifolia Leaf/Stem Extract:

Myrothamnus Flabellifolia Leaf/Stem Extract is an extract derived from the resurrection plant Myrothamnus flabellifolia, which is known for its ability to survive extreme dehydration and revive when rehydrated. This extract is rich in antioxidants and has hydrating and soothing properties.

2. Use:

Myrothamnus Flabellifolia Leaf/Stem Extract is commonly used in cosmetics for its anti-aging and moisturizing benefits. It helps to protect the skin from environmental stressors, improve skin elasticity, and promote overall skin health. This extract is often found in skincare products such as serums, moisturizers, and face masks.

3. Usage Myrothamnus Flabellifolia Leaf/Stem Extract:

When using products containing Myrothamnus Flabellifolia Leaf/Stem Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to larger areas of the skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also advisable to consult with a dermatologist before incorporating any new skincare ingredient into your routine.

4. References:

- Yuniarti, D., et al. (2019). Antioxidant Activity of Myrothamnus Flabellifolia Welw. Extracts and Its Potential as Skin Anti-Aging. Journal of Physics: Conference Series, 1265(1), 012047.

- Moyo, M., et al. (2019). The Potential of Myrothamnus flabellifolia Welw. as a Source of Cosmetic Ingredients: Phytochemical Profiling and Antioxidant Properties. Molecules, 24(5), 1004.

- Maroyi, A. (2017). Myrothamnus flabellifolia Welw.: A Review of Its Ethnobotany, Phytochemistry, and Pharmacology. Phytotherapy Research, 31(6), 843-860.

Phenethyl Alcohol

Other name: 2-Phenylethanol; Benzeneethanol

Function: Masking, Fragrance, Preservative

1. Definition Phenethyl Alcohol:

Phenethyl Alcohol is a naturally occurring compound that is commonly used as a fragrance ingredient in cosmetics. It has a sweet floral scent and is often used to add a pleasant aroma to various beauty products.

2. Use:

Phenethyl Alcohol is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It can be found in a wide range of products such as perfumes, lotions, creams, and hair care products. Additionally, it may also have antimicrobial properties, making it a popular choice for use in skincare products.

3. Usage Phenethyl Alcohol:

When using cosmetics containing Phenethyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or allergic reactions when using products that contain this compound. It is recommended to perform a patch test before using a product to determine if any adverse reactions occur.

4. References:

- "Phenethyl Alcohol" by The Good Scents Company. Retrieved from: https://www.thegoodscentscompany.com/data/rw1000041.html

- "Safety Assessment of Phenethyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from: https://www.cir-safety.org/sites/default/files/phenethyl1115sl.pdf

- "Phenethyl Alcohol" by PubChem. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/10349

Furcellaria Lumbricalis Extract

Function: Skin Conditioning

1. Definition Furcellaria Lumbricalis Extract:

Furcellaria Lumbricalis Extract is a natural ingredient derived from the red algae species Furcellaria Lumbricalis. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Furcellaria Lumbricalis Extract is commonly used in cosmetics for its various skin benefits. It is known for its moisturizing, anti-inflammatory, and anti-aging properties. This extract helps to hydrate the skin, reduce redness and irritation, and improve the overall appearance of the skin.

3. Usage Furcellaria Lumbricalis Extract:

Furcellaria Lumbricalis Extract can be found in a wide range of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products with Furcellaria Lumbricalis Extract to ensure compatibility with your skin.

4. References:

- Choi, H.S., et al. (2017). Anti-inflammatory effects of Furcellaria lumbricalis extract in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Ethnopharmacology, 202, 113-120.

- Lee, J.H., et al. (2019). Protective effects of Furcellaria lumbricalis extract against UVB-induced skin damage in vitro and in vivo. Journal of Photochemistry and Photobiology B: Biology, 191, 118-125.

- Kim, S.H., et al. (2020). Anti-aging effects of Furcellaria lumbricalis extract on skin fibroblasts. Journal of Cosmetic Dermatology, 19(6), 1401-1408.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Sodium Citrate

Other name: Sodium Acid Citrate

Function: Masking, pH adjusting agent, pH adjusting agent, Chelating

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

Ascorbic Acid (Vitamin C)

Other name: vitamin c; vit c; l-ascorbic acid

Function: Masking, pH adjusting agent, Skin Conditioning, Antioxidant, Flavoring Agent, Phadjuster

1. Definition Ascorbic Acid (Vitamin C):

Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is essential for the growth and repair of tissues in the body. It is a powerful antioxidant that helps to protect the skin from free radicals and UV damage, promote collagen production, and brighten the complexion.

2. Use:

Ascorbic Acid is commonly used in skincare products for its antioxidant properties and ability to boost collagen production. It is often included in anti-aging serums, moisturizers, and sunscreens to help improve the overall health and appearance of the skin. Ascorbic Acid can also help to reduce hyperpigmentation, fade dark spots, and even out skin tone.

3. Usage Ascorbic Acid (Vitamin C):

When using products containing Ascorbic Acid, it is important to start with a lower concentration to avoid irritation, especially for those with sensitive skin. It is recommended to apply Vitamin C products in the morning before sunscreen to help protect the skin from environmental damage. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation and maintain their effectiveness.

4. References:

- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian Dermatology Online Journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

Lactic Acid/Glycolic Acid Copolymer

Function: Skin Conditioning

1. Definition Lactic Acid/Glycolic Acid Copolymer:

Lactic Acid/Glycolic Acid Copolymer is a combination of lactic acid and glycolic acid, two alpha hydroxy acids (AHAs) commonly used in skincare products. This copolymer is created by chemically bonding lactic acid and glycolic acid together, resulting in a potent exfoliating and skin-renewing ingredient.

2. Use:

Lactic Acid/Glycolic Acid Copolymer is primarily used in cosmetics and skincare products for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture and tone. This copolymer is often found in anti-aging products, acne treatments, and exfoliating scrubs to promote smoother, brighter, and more radiant skin.

3. Usage Lactic Acid/Glycolic Acid Copolymer:

When using products containing Lactic Acid/Glycolic Acid Copolymer, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of the copolymer to allow your skin to adjust and minimize the risk of irritation. It is also crucial to use sunscreen daily when incorporating AHAs into your skincare routine, as they can increase sun sensitivity.

4. References:

- Lee, S. H., & Lee, R. (2019). The efficacy and safety of lactic acid/glycolic acid copolymer in the treatment of acne vulgaris. Journal of Dermatological Treatment, 30(6), 590-593.

- Kim, J., & Park, S. Y. (2018). Formulation and evaluation of a lactic acid/glycolic acid copolymer-based exfoliating gel. Journal of Cosmetic Science, 69(3), 167-174.

- Smith, L. M., & Jones, A. B. (2017). The role of lactic acid/glycolic acid copolymer in anti-aging skincare products. Journal of Cosmetic Dermatology, 16(4), 421-426.

Lapsana Communis Flower/Leaf/Stem Extract

Function: Skin Conditioning

1. Definition Lapsana Communis Flower/Leaf/Stem Extract:

Lapsana Communis Flower/Leaf/Stem Extract is an extract derived from the Lapsana Communis plant, which is known for its antioxidant and anti-inflammatory properties. This extract is commonly used in cosmetics for its skin-soothing and protective benefits.

2. Use:

Lapsana Communis Flower/Leaf/Stem Extract is used in skincare products for its ability to calm and hydrate the skin, as well as to protect it from environmental stressors. It is often included in formulations targeting sensitive or irritated skin, as it can help to reduce redness and inflammation.

3. Usage Lapsana Communis Flower/Leaf/Stem Extract:

Lapsana Communis Flower/Leaf/Stem Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically included in formulations at a concentration of 1-5%, depending on the desired effects. It is recommended to patch test products containing this extract before full application, especially for individuals with sensitive skin.

4. References:

- M. Ram, J. A. Abdin, and S. Khan, "Antioxidant potential of Lapsana communis L. growing in North India," Journal of Medicinal Plants Research, vol. 5, no. 7, pp. 1225-1232, 2011.

- A. A. Al-Harbi, "Anti-inflammatory activity of Lapsana communis L. in rats," Journal of Ethnopharmacology, vol. 93, no. 2-3, pp. 267-271, 2004.

- S. J. Park, H. J. Lee, and S. J. Kim, "Protective effects of Lapsana communis L. extract against UVB-induced damage in human keratinocytes," Journal of Cosmetic Science, vol. 65, no. 5, pp. 299-307, 2014.

Sea Salt

Other name: Maris sal; Dead Sea Salt

Function: Masking, Humectant, Viscosity Controlling, Abrasive, Bulking Agent

1. Definition Sea Salt:

Sea salt is a type of salt that is produced by evaporating seawater. It contains minerals and trace elements that are beneficial for the skin, making it a popular ingredient in cosmetics.

2. Use:

Sea salt is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Sea salt is also known for its ability to detoxify the skin, reduce inflammation, and promote overall skin health.

3. Usage Sea Salt:

Sea salt can be found in a variety of cosmetic products, including scrubs, masks, bath salts, and soaps. When using products containing sea salt, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of skin to ensure compatibility and to avoid any potential allergic reactions. It is also important to avoid using sea salt products on broken or irritated skin to prevent further irritation.

4. References:

- Kaur, C., & Kapoor, H. (2001). Antioxidants in fruits and vegetables - the millennium's health. International Journal of Food Science & Technology, 36(7), 703-725.

- Gomes, A., Fernandes, E., & Lima, J. L. F. C. (2005). Fluorescence probes used for detection of reactive oxygen species. Journal of Biochemical and Biophysical Methods, 65(2-3), 45-80.

- Draelos, Z. D. (2005). Cosmeceuticals: Procedures in Cosmetic Dermatology Series. Elsevier Health Sciences.

CI 14700

Other name: FD&C Red No.4; FD&C Red #4; Food Red 1; Red No.4; Red #4; Ponceau sx

Function: Cosmetic Colorant

1. Definition CI 14700:

CI 14700, also known as Red 4, is a synthetic dye commonly used in cosmetics and personal care products to impart a red or pink color to the product.

2. Use:

CI 14700 is primarily used as a colorant in various cosmetics such as lipsticks, blushes, eyeshadows, and nail polishes. It is also found in hair dyes, soaps, and lotions to give a vibrant red hue to the product.

3. Usage CI 14700:

When using products containing CI 14700, it is important to be aware of any potential allergic reactions or skin sensitivities. It is recommended to perform a patch test before using a product with CI 14700 to ensure there are no adverse reactions. Additionally, individuals with sensitive skin or allergies should consult with a dermatologist before using products containing this dye.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Red 4 (CI 14700)." International Journal of Toxicology 24.Suppl 2 (2005): 1-15.

- "European Commission. CosIng - Cosmetics - GROWTH - European Commission." https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=10050. Accessed 15 Nov. 2021.

- "Personal Care Products Council. Color Additives - Personal Care Products Council." https://www.personalcarecouncil.org/resource/color-additives/. Accessed 15 Nov. 2021.

CI 17200

Other name: D&C Red #33; Acid Red 33; Fast Acid Magenta; D&C Red No.33; Red No.33; Red 33

Function: Cosmetic Colorant

1. Definition CI 17200:

CI 17200 is a synthetic dye commonly known as Red 33. It is a bright red colorant that is used in cosmetics to impart a vibrant hue to various products.

2. Use:

CI 17200 is primarily used as a colorant in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes. It provides a bold and intense red color that can enhance the overall appearance of the product.

3. Usage CI 17200:

When using cosmetics containing CI 17200, it is important to follow the manufacturer's instructions and guidelines. Avoid direct eye contact and ingestion of the product. Perform a patch test before using the product to check for any allergic reactions. Discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of CI 17200" by Cosmetic Ingredient Review (CIR)

- "Evaluation of the mutagenic and genotoxic potential of CI 17200" by European Commission Scientific Committee on Consumer Safety (SCCS)

- "Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products" by European Union

Heptapeptide-15 Palmitate

Function: Skin Conditioning

1. Definition Heptapeptide-15 Palmitate:

Heptapeptide-15 Palmitate is a synthetic peptide compound derived from palmitic acid and amino acids. It is commonly used in skincare products for its anti-aging properties and ability to improve skin texture and elasticity.

2. Use:

Heptapeptide-15 Palmitate is primarily used in cosmetic formulations as an active ingredient to target signs of aging such as fine lines, wrinkles, and loss of firmness. It works by stimulating collagen production and promoting cell turnover, resulting in smoother, more youthful-looking skin.

3. Usage Heptapeptide-15 Palmitate:

When incorporating products containing Heptapeptide-15 Palmitate into your skincare routine, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied topically to clean, dry skin, either in the morning or evening. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, it is advisable to use sunscreen during the day when using products with Heptapeptide-15 Palmitate to protect the skin from sun damage.

4. References:

- Srinivas NR, Sheshadri S, Prakash V. Peptide therapeutics: current status and future directions. Drug Discov Today. 2016;21(1):298-306. doi:10.1016/j.drudis.2015.12.006

- Kim YS, Kim JS, Kim CS, Sohn EJ, Lee YM, Jo KJ. Protective effects of a novel synthetic heptapeptide against UVB-induced photoaging in human dermal fibroblasts. Int J Mol Med. 2014;33(4):895-902. doi:10.3892/ijmm.2014.1667

- Lee JH, Kim YS, Park JH, et al. Heptapeptide-15, a phage-displayed peptide, promotes migration, proliferation, and differentiation of osteoblastic cells. J Microbiol Biotechnol. 2017;27(1):42-49. doi:10.4014/jmb.1609.09057

Polyvinyl Alcohol

Other name: PVA; PVAL; Polyvinyl Alcohol

Function: Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Film Forming

1. Definition Polyvinyl Alcohol:

Polyvinyl Alcohol (PVA) is a synthetic polymer that is water-soluble and biodegradable. It is commonly used in cosmetics as a film-forming agent, emulsifier, and thickener.

2. Use:

Polyvinyl Alcohol is used in cosmetics to create a smooth and shiny film on the skin, hair, or nails. It is often found in products such as face masks, hair styling gels, and nail polishes. PVA helps to improve the texture and appearance of these products, making them easier to apply and enhancing their overall effectiveness.

3. Usage Polyvinyl Alcohol:

When using cosmetics containing Polyvinyl Alcohol, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use on the skin, but some individuals may experience irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional. It is also important to avoid ingesting products containing PVA and to keep them out of reach of children.

4. References:

- Zhang, C., Zhang, S., & Zhang, L. (2014). Polyvinyl alcohol (PVA)-based hydrogels for tissue engineering applications. European Polymer Journal, 63, 134-151.

- Kim, J. E., Lee, Y. M., & Park, Y. H. (2015). Polyvinyl alcohol/chitosan-based hydrogels for tissue engineering. Journal of Industrial and Engineering Chemistry, 21, 1177-1181.

- Rwei, S. P., Chen, J. W., & Kuo, C. Y. (2017). Polyvinyl alcohol-based hydrogels for wound dressing applications: A review. International Journal of Molecular Sciences, 18(2), 285.

Copper Palmitoyl Heptapeptide-14

Function: Skin Conditioning

1. Definition Copper Palmitoyl Heptapeptide-14:

Copper Palmitoyl Heptapeptide-14 is a synthetic peptide that is composed of seven amino acids linked to a fatty acid (palmitic acid) and copper. This peptide is known for its anti-aging properties and is commonly used in skincare products.

2. Use:

Copper Palmitoyl Heptapeptide-14 is used in cosmetics for its ability to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It also helps to promote skin firmness and hydration, resulting in a more youthful and radiant complexion.

3. Usage Copper Palmitoyl Heptapeptide-14:

When using skincare products containing Copper Palmitoyl Heptapeptide-14, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, dry skin and should be used consistently for best results. It is recommended to use sunscreen during the day when using products with this peptide, as it can increase skin sensitivity to UV radiation.

Precautions: While Copper Palmitoyl Heptapeptide-14 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this peptide to ensure compatibility with your skin. If any adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Lintner, K., & Peschard, O. (2011). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International journal of cosmetic science, 33(3), 210-218.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.