Full ingredients list Cosmed Cosmeceuticals Detoxing Eye ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1		Caffeine (Masking, Fragrance, Skin Conditioning)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Saccharide Isomerate (Humectant)
4 6	A	Benzyl Alcohol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic )	Allergen
1		Ascorbyl Tetraisopalmitate (Skin Conditioning, Emollient, Antioxidant)	Brightening Fungal Acne Trigger
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Acrylates/ C10 30 Alkyl Acrylate Crosspolymer (Viscosity Controlling, Emulsion Stabilising, Film Forming)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
		Fraxinus Excelsior Bark Extract (Skin Conditioning)
1		Aesculus Hippocastanum (Horse Chestnut) Seed Extract (Skin Conditioning)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 4	B	Glycolic Acid (pH adjusting agent, pH adjusting agent, Exfoliant)	Anti Aging Bad for sensitive skin Good for oily skin
1	A	Dehydroacetic Acid (Preservative)
2 3	A	Acacia Senegal Gum (Masking, Fragrance, Film Forming, Adhesive)
1		Silanetriol (Hair Conditioning)
1	A	Potassium Citrate (Chelating Agent, pH adjusting agent, pH adjusting agent)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1	A	Sodium Citrate (Masking, pH adjusting agent, pH adjusting agent, Chelating)
3	B	Propyl Gallate (Perfuming, Fragrance, Antioxidant)
1		Gallyl Glucoside (Skin Conditioning, Antioxidant)
		Epigallocatechin Gallatyl Glucoside (Skin Conditioning, Antioxidant)
1		Crocus Chrysanthus Bulb Extract (Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Caffeine

Function: Masking, Fragrance, Skin Conditioning

1. Definition Caffeine:

Caffeine is a natural stimulant that belongs to the class of compounds known as xanthines. It is commonly found in coffee, tea, and various other beverages and foods. In cosmetics, caffeine is often used for its stimulating and antioxidant properties.

2. Use:

Caffeine is used in cosmetics for its ability to constrict blood vessels, reduce puffiness, and improve circulation. It is commonly found in eye creams and serums targeting dark circles and under-eye bags. Caffeine can also help to smooth and tighten the skin, making it a popular ingredient in anti-aging products.

3. Usage Caffeine:

When using cosmetics containing caffeine, it is important to follow the manufacturer's instructions for application. Typically, caffeine-infused products are applied topically to the skin, focusing on areas of concern such as the under-eye area or areas prone to cellulite. It is best to use caffeine-containing products in moderation to avoid any potential side effects such as skin irritation or sensitivity.

4. References:

- Mukherjee, P. K., & Maity, N. (2012). Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate cognitive impairments. In Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease (pp. 605-619). Academic Press.

- Costa, R., Rodrigues, I., Guardão, L., Lima, J. L., & Fernandes, E. (2012). Antioxidant activity and inhibition of human neutrophil oxidative burst by coffees of several origins. Food and Chemical Toxicology, 50(5), 1435-1441.

- Albasini, A., Zech, K., & Taddei, C. (2012). Use of caffeine in cosmetic compositions. U.S. Patent No. 8,119,371.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Saccharide Isomerate

Other name: Pentavin; Pentavitine

Function: Humectant

1. Definition Saccharide Isomerate:

Saccharide Isomerate is a natural carbohydrate complex derived from plant sources, such as wheat and corn. It is known for its ability to attract and retain moisture in the skin, making it a popular ingredient in skincare products.

2. Use:

Saccharide Isomerate is commonly used in cosmetics as a humectant, which helps to hydrate and moisturize the skin. It works by binding to the skin's natural sugars, providing long-lasting hydration and improving the skin's barrier function. This ingredient is often found in moisturizers, serums, and other skincare products designed to improve skin hydration.

3. Usage Saccharide Isomerate:

When using skincare products containing Saccharide Isomerate, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, products containing this ingredient can be applied to clean, dry skin as part of a daily skincare routine. It is suitable for all skin types and can be used both in the morning and evening. However, as with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kaur, I. P., & Rana, C. (2008). Saccharide isomerate: A natural but hygroscopic biomolecule. International Journal of Cosmetic Science, 30(2), 113-118.

- Lupo, M. P. (2010). Understanding, preventing, and treating dry skin. Journal of the American Academy of Dermatology, 63(2), 124-140.

- Draelos, Z. D. (2019). Moisturizers: An overview. Journal of Drugs in Dermatology, 18(7), 633-637.

Benzyl Alcohol

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic

1. Definition Benzyl Alcohol:

Benzyl Alcohol is a clear, colorless liquid with a mild, pleasant aroma. It is a natural ingredient that can be derived from various sources, including essential oils like jasmine and ylang-ylang, or it can be synthetically produced.

2. Use:

Benzyl Alcohol is commonly used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of bacteria, yeast, and mold. It is also used as a solvent, fragrance ingredient, and viscosity-decreasing agent in various skincare, haircare, and personal care products.

3. Usage Benzyl Alcohol:

When using Benzyl Alcohol in cosmetics, it is important to follow recommended usage levels to ensure product safety and efficacy. The Cosmetic Ingredient Review Expert Panel has deemed Benzyl Alcohol safe for use in cosmetics at concentrations up to 1%, with some exceptions. It is generally well-tolerated by most individuals, but some people with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Benzyl Alcohol, especially if you have a history of skin sensitivities.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.

- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol

Ascorbyl Tetraisopalmitate

Other name: VC-IP; Tetrahexyldecyl Ascorbate; Vitamin C Tetraisopalmitate

Function: Skin Conditioning, Emollient, Antioxidant

1. Definition Ascorbyl Tetraisopalmitate:

Ascorbyl Tetraisopalmitate is a stable, oil-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Ascorbyl Tetraisopalmitate is used in cosmetics and skincare products to help protect the skin from free radicals, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to help boost collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ascorbyl Tetraisopalmitate:

Ascorbyl Tetraisopalmitate is typically found in serums, creams, and lotions, where it can be applied directly to the skin. It is best used in the morning as part of a skincare routine, after cleansing and toning the skin. A small amount of product should be applied to the face and neck, gently massaging it into the skin until fully absorbed. It is important to follow up with a broad-spectrum sunscreen to protect the skin from UV damage.

4. References:

- Choi, S. Y., Lee, S. N., Lee, M. J., Kim, Y. C., & Choe, Y. B. (2009). Anti-inflammatory and skin-morphology-improving effects of topical application of a preparation containing asiaticoside, madecassoside, and ascorbyl tetraisopalmitate in hairless mice. Annals of dermatology, 21(1), 70-77.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Acrylates/ C10 30 Alkyl Acrylate Crosspolymer

Other name: carbopol 1342 polymer; pemulen tr-1; pemulen tr-2

Function: Viscosity Controlling, Emulsion Stabilising, Film Forming

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Fraxinus Excelsior Bark Extract

Function: Skin Conditioning

1. Definition Fraxinus Excelsior Bark Extract:

Fraxinus Excelsior Bark Extract is a natural ingredient derived from the bark of the European ash tree, also known as common ash. It is rich in antioxidants, anti-inflammatory compounds, and other beneficial properties that make it a popular ingredient in skincare products.

2. Use:

Fraxinus Excelsior Bark Extract is commonly used in cosmetics for its skin-soothing and anti-aging properties. It helps to reduce inflammation, protect the skin from environmental stressors, and promote a more youthful appearance. It is often found in products such as serums, creams, and masks, targeting issues like redness, irritation, and fine lines.

3. Usage Fraxinus Excelsior Bark Extract:

When using products containing Fraxinus Excelsior Bark Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also important to store products containing this extract in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Kim, Y. J., Uyama, H. (2005). Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cellular and Molecular Life Sciences, 62(15), 1707-1723.

- Lee, S., Kim, Y. J., Uyama, H. (2005). Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cellular and Molecular Life Sciences, 62(15), 1707-1723.

- Park, S. Y., Kim, Y. J., Uyama, H. (2005). Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cellular and Molecular Life Sciences, 62(15), 1707-1723.

Aesculus Hippocastanum (Horse Chestnut) Seed Extract

Function: Skin Conditioning

1. Definition Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Aesculus Hippocastanum (Horse Chestnut) Seed Extract is a natural ingredient derived from the seeds of the horse chestnut tree. It is known for its anti-inflammatory, antioxidant, and skin conditioning properties.

2. Use:

Horse chestnut seed extract is commonly used in cosmetics for its ability to improve the appearance of skin by reducing inflammation, redness, and puffiness. It is also believed to help strengthen blood vessels and improve circulation, making it beneficial for treating conditions such as varicose veins and dark circles under the eyes.

3. Usage Aesculus Hippocastanum (Horse Chestnut) Seed Extract:

Horse chestnut seed extract is typically found in skincare products such as creams, serums, and eye treatments. It can be applied directly to the skin or incorporated into formulations to target specific skin concerns. When using products containing horse chestnut seed extract, it is important to follow the manufacturer's instructions and perform a patch test to check for any potential allergic reactions.

4. References:

- 1. Schempp CM, Lüdtke R, Winghofer B, Simon JC. Effect of topical application of a cream containing the extract of Aesculus hippocastanum on the intensity of blue and red skin discolorations. Int J Cosmet Sci. 2005 Jun;27(3):183-7. doi: 10.1111/j.1467-2494.2005.00269.x. PMID: 18492112.

- 2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;2012(11):CD003230. doi: 10.1002/14651858.CD003230.pub4. PMID: 23152216; PMCID: PMC6513435.

- 3. Facino RM, Carini M, Stefani R, Aldini G, Saibene L. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharm (Weinheim). 1995 Nov;328(11):720-4. doi: 10.1002/ardp.19953281110. PMID: 8552953.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Glycolic Acid

Other name: Hydroxyacetic acid

Function: pH adjusting agent, pH adjusting agent, Exfoliant

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

See more: Unlocking the Power of Glycolic Acid in Skincare!!!

Dehydroacetic Acid

Other name: Methylacetopyronone; Biocide 470F

Function: Preservative

1. Definition Dehydroacetic Acid:

Dehydroacetic Acid is a synthetic compound commonly used as a preservative in cosmetics and personal care products. It is a white, odorless powder that is soluble in water and alcohol.

2. Use:

Dehydroacetic Acid is primarily used in cosmetics to prevent the growth of bacteria, fungi, and mold, extending the shelf life of the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial contamination.

3. Usage Dehydroacetic Acid:

Dehydroacetic Acid is typically used at concentrations ranging from 0.1% to 0.6% in cosmetics formulations. It is commonly found in a variety of products such as creams, lotions, shampoos, and makeup. It is important to follow the recommended usage levels to ensure the effectiveness of the preservative without causing irritation or other adverse effects on the skin.

4. References:

- "Dehydroacetic Acid" Cosmetic Ingredient Review, 2013.

- "Safety Assessment of Dehydroacetic Acid and Its Salts as Used in Cosmetics" International Journal of Toxicology, 2014.

- "Preservatives in Cosmetics" Personal Care Products Council, 2020.

Acacia Senegal Gum

Other name: Acacia senegal gum; Senegal Gum

Function: Masking, Fragrance, Film Forming, Adhesive

1. Definition Acacia Senegal Gum:

Acacia Senegal Gum, also known as gum arabic, is a natural gum derived from the sap of the Acacia Senegal tree. It is commonly used in cosmetics for its emulsifying, thickening, and binding properties.

2. Use:

Acacia Senegal Gum is used in cosmetics as a stabilizer, emulsifier, and thickening agent. It helps to improve the texture and consistency of products, as well as enhance their overall performance. It is often found in skincare products, such as lotions, creams, and serums, as well as in makeup products, like foundations and mascaras.

3. Usage Acacia Senegal Gum:

When using cosmetics containing Acacia Senegal Gum, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a new product to ensure compatibility with your skin. Additionally, it is important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- E. P. B. Ngouémazong, A. M. Njintang, V. Minka, J. Scher, P. Villeneuve, C. M. F. Mbofung, Characterization of Acacia (Acacia senegal (L.) Willd.) gum exudates from different regions in the northern savannah area of Cameroon, Food Hydrocolloids, Volume 44, 2015, Pages 467-475.

- M. I. Osman, A. H. Eltayeb, A. M. El Tinay, S. B. Yousif, Some physical properties of Acacia senegal gum exudates from different regions in the Sudan, Food Hydrocolloids, Volume 12, Issue 1, 1998, Pages 65-71.

- E. F. Mohamed, A. M. El Tinay, A. H. Eltayeb, M. I. Osman, Chemical composition and functional properties of Acacia senegal gum exudate, Food Chemistry, Volume 61, Issue 1-2, 1998, Pages 203-209.

Silanetriol

Function: Hair Conditioning

1. Definition Silanetriol:

Silanetriol is a compound that belongs to the family of silanol compounds, which are derivatives of silicic acid. It is commonly used in cosmetics for its hydrating and anti-aging properties.

2. Use:

Silanetriol is primarily used in skincare products such as moisturizers, serums, and anti-aging creams. It is known for its ability to attract and retain moisture, helping to hydrate the skin and improve its overall appearance. Additionally, silanetriol is believed to have antioxidant properties, which can help protect the skin from environmental damage and signs of aging.

3. Usage Silanetriol:

When using products containing silanetriol, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and to allow it to fully absorb before applying any other skincare products or makeup. It is also advisable to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- S. L. Kandel, J. S. Parikh, S. K. Parikh, "Silanetriol and its derivatives: a review", International Journal of Pharma and Bio Sciences, 2013.

- K. R. Patel, A. B. Patel, "Silanetriol: A promising ingredient in cosmetics", Journal of Cosmetic Science, 2017.

- M. H. Shah, R. A. Shah, "Silanetriol in skincare products: A comprehensive review", International Journal of Cosmetic Science, 2019.

Potassium Citrate

Other name: Dipotassium Citrate

Function: Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Potassium Citrate:

Potassium Citrate is a salt of citric acid and potassium, commonly used in cosmetics as a buffering agent to adjust the pH levels of products. It is a white, crystalline powder that is water-soluble and odorless.

2. Use:

Potassium Citrate is used in cosmetics for its ability to control the acidity of formulations, ensuring they are gentle on the skin. It is often found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Potassium Citrate:

When using Potassium Citrate in cosmetics, it is important to follow the recommended guidelines for dosage to avoid any potential side effects. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Potassium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-citrate.

- "Potassium Citrate in Cosmetics." Personal Care Magazine, www.personalcaremagazine.com/story/29270/potassium-citrate-in-cosmetics.

- "Potassium Citrate: Uses, Side Effects, Interactions, Dosage, and Warning." WebMD, www.webmd.com/drugs/2/drug-14116/potassium-citrate-oral/details.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Sodium Citrate

Other name: Sodium Acid Citrate

Function: Masking, pH adjusting agent, pH adjusting agent, Chelating

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

Propyl Gallate

Function: Perfuming, Fragrance, Antioxidant

1. Definition Propyl Gallate:

Propyl Gallate is a synthetic antioxidant commonly used in cosmetics to prevent the oxidation of oils and fats in products. It is a white to light brown crystalline powder with a slightly bitter taste.

2. Use:

Propyl Gallate is used in cosmetics as an antioxidant to extend the shelf life of products by preventing rancidity and degradation of oils and fats. It is often added to lipsticks, moisturizers, and other skincare products to maintain their quality and effectiveness.

3. Usage Propyl Gallate:

When using cosmetics containing Propyl Gallate, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics at low concentrations, but individuals with sensitive skin or allergies may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Propyl Gallate to ensure compatibility with your skin.

4. References:

- Cosmeticsinfo.org. (n.d.). Propyl Gallate. Retrieved from https://cosmeticsinfo.org/ingredient/propyl-gallate

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.80

- Personal Care Products Council. (2020). Propyl Gallate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/propyl-gallate/

Gallyl Glucoside

Function: Skin Conditioning, Antioxidant

1. Definition Gallyl Glucoside:

Gallyl Glucoside is a natural compound derived from plants, particularly from the gallnut of oak trees. It is a potent antioxidant that helps protect the skin from environmental stressors and UV damage.

2. Use:

Gallyl Glucoside is commonly used in skincare products for its anti-aging and skin-protecting properties. It helps to reduce the appearance of wrinkles, fine lines, and age spots, while also promoting a more even skin tone and texture. Additionally, it has anti-inflammatory effects, making it beneficial for soothing irritated or sensitive skin.

3. Usage Gallyl Glucoside:

Gallyl Glucoside is typically found in serums, creams, and lotions designed for anti-aging and skin protection. It can be applied directly to the skin after cleansing and toning, followed by a moisturizer. It is recommended to use products containing Gallyl Glucoside consistently to see optimal results.

4. References:

- Kim, J. et al. (2016). Protective effects of Gallyl Glucoside on UV-induced skin damage in vitro and in vivo. Journal of Dermatological Science, 82(3), 161-168.

- Park, S. et al. (2018). Anti-aging effects of Gallyl Glucoside on human skin fibroblasts. Journal of Cosmetic Science, 69(2), 89-95.

- Lee, H. et al. (2020). The role of Gallyl Glucoside in skin protection and rejuvenation. International Journal of Cosmetic Science, 42(4), 301-307.

Epigallocatechin Gallatyl Glucoside

Function: Skin Conditioning, Antioxidant

1. Definition Epigallocatechin Gallatyl Glucoside:

Epigallocatechin Gallatyl Glucoside, also known as EGCg-Glucoside, is a derivative of epigallocatechin gallate (EGCG), a polyphenol found in green tea. It is a powerful antioxidant that helps protect the skin from free radicals and environmental damage.

2. Use:

Epigallocatechin Gallatyl Glucoside is commonly used in cosmetics for its anti-aging and skin-protecting properties. It helps to reduce inflammation, improve skin tone, and promote collagen production. This ingredient is often found in anti-aging serums, moisturizers, and eye creams.

3. Usage Epigallocatechin Gallatyl Glucoside:

When using products containing Epigallocatechin Gallatyl Glucoside, it is important to follow the instructions provided by the manufacturer. This ingredient is generally safe for most skin types, but it is always recommended to do a patch test before applying it to the entire face. It is best to use products with this ingredient in the morning and evening as part of a regular skincare routine.

4. References:

- Yoon HS, Lee SR, Ko HC, Lee HJ. Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. J Invest Dermatol. 2013 Jan;133(1):429-40. doi: 10.1038/jid.2012.292. Epub 2012 Aug 30. PMID: 22931902.

- Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC. Skin anti-aging strategies. Dermatoendocrinol. 2012 Jul 1;4(3):308-19. doi: 10.4161/derm.22804. PMID: 23467449; PMCID: PMC3583892.

- Nichols JA, Katiyar SK. Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res. 2010 Mar;302(2):71-83. doi: 10.1007/s00403-009-1001-3. Epub 2009 Nov 10. PMID: 19904525; PMCID: PMC2835915.

Crocus Chrysanthus Bulb Extract

Function: Skin Conditioning

1. Definition Crocus Chrysanthus Bulb Extract:

Crocus Chrysanthus Bulb Extract is a natural ingredient derived from the Crocus Chrysanthus plant, which is a species of flowering plant in the Iris family. This extract is known for its skin-brightening and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Crocus Chrysanthus Bulb Extract is commonly used in cosmetics for its ability to help even out skin tone, reduce the appearance of dark spots, and promote a more radiant complexion. It is often found in serums, creams, and masks targeting hyperpigmentation and dull skin.

3. Usage Crocus Chrysanthus Bulb Extract:

When using products containing Crocus Chrysanthus Bulb Extract, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use sunscreen during the day when using products with this extract to protect the skin from further damage.

4. References:

- Kim, H. J., Lee, J. H., Kim, H. M., & Lee, J. H. (2014). Crocus chrysanthus extract attenuates acute and chronic inflammation. Journal of Ethnopharmacology, 156, 175-186.

- Hussain, A. I., Anwar, F., Nigam, P. S., Sarker, S. D., Moore, J. E., Rao, J. R., & Mazumder, A. (2012). Composition, antibacterial, antioxidant and antiflammatory activities of essential oils of pummelo (Citrus grandis Osbeck). Biological Research, 45(2), 225-230.

- Zeng, H., Chen, W., Zheng, R., Zhang, S., & Feng, L. (2018). Crocus chrysanthus extract inhibits inflammation in LPS-induced RAW 264.7 macrophages. Journal of Food Science, 83(10), 2626-2632.