Full ingredients list MyChelle Dermaceuticals Fruit Enzyme ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
2	A	Potassium Sorbate (Fragrance, Preservative)
1	B	Ethanol (pH adjusting agent, pH adjusting agent)
1	A	Calendula Officinalis (Pot Marigold) Flower Extract (Skin Conditioning, Masking, Perfuming)
1	A	Maltodextrin (Hair Conditioning, Skin Conditioning, Absorbent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Suspending Agent - Nonsurfactant)
1	A	Behenyl Alcohol (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
5		Glycyrrhiza Glabra (Licorice) Root Extract (Perfuming, Humectant, Skin Conditioning, Antioxidant)	Brightening Acne fighting
1		Trisodium Ethylenediamine Disuccinate (Chelating Agent)
1	B	Phenethyl Alcohol (Masking, Fragrance, Preservative)
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Hamamelis Virginiana (Witch Hazel) Water (Skin Conditioning, Drug Astringent - Skin Protecting)	Good for oily skin
1	B	Sodium Stearoyl Glutamate (Hair Conditioning, Skin Conditioning, Emulsifying, Surfactant)
1		Dicaprylyl Ether (Solvent, Skin Conditioning, Emollient)
1		Cymbopogon (Lemon Grass) Oil (Masking, Fragrance, Tonic)	Bad for sensitive skin
1		Sucrose Stearate (Skin Conditioning, Emollient, Surfactant, Emulsifying)	Fungal Acne Trigger
1		Bambusa Arundinacea (Bamboo) Stem Extract (Skin Conditioning)
1	A	Hydrolyzed Wheat Starch (Skin Conditioning, Humectant, Viscosity Controlling)
1	A	Panthenol, D (Skin Conditioning, Antistatic Agent, Hair Conditioning)	Promotes Wound Healing Good for dry skin
1	A	Pectin (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
1		Ruscus Aculeatus (Box Holly) Root Extract (Skin Conditioning, Stabilising, Soothing, Tonic, Astringent, Refreshing)
1		Hydrolyzed Yeast Protein (Skin Conditioning, Hair Conditioning)
1		Simmondsia Chinensis (Jojoba) Beads
1		Vaccinium Macrocarpon (Cranberry) Fruit (Skin Conditioning)
1		Vaccinium Macrocarpon (Cranberry) Fruit Juice (Skin Conditioning)
1		Aesculus Hippocastanum (Horse Chestnut) Bark Extract (Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Potassium Sorbate

Function: Fragrance, Preservative

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

Ethanol

Other name: Ethanol; Grain Alcohol; Ethyl Alcohol

Function: pH adjusting agent, pH adjusting agent

1. Definition Ethanol:

Ethanol, also known as ethyl alcohol, is a clear, colorless liquid commonly used in cosmetics as a solvent, preservative, or as an ingredient in skincare and haircare products.

2. Use:

Ethanol is used in cosmetics for a variety of purposes, including as a solvent to dissolve other ingredients, as a preservative to extend the shelf life of products, and as an astringent to help tighten and tone the skin. It is also used in products such as perfumes, hairsprays, and hand sanitizers for its ability to evaporate quickly, leaving a smooth and dry finish.

3. Usage Ethanol:

When using cosmetics containing ethanol, it is important to take precautions to avoid irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any sensitivity. Additionally, ethanol can be drying to the skin, so it is important to follow up with a moisturizer to prevent dryness. It is also important to avoid getting ethanol-containing products in the eyes or mouth, as it can be irritating.

4. References:

- Burdock, G. A. (2010). Safety assessment of ethanol in cosmetic products. International Journal of Toxicology, 29(1), 69-79.

- Lachenmeier, D. W., & Rehm, J. (2015). Comparative risk assessment of carcinogens in alcoholic beverages using the margin of exposure approach. International Journal of Cancer, 136(5), 1464-1475.

- Reisch, M. S., & Givens, J. (2016). Ethanol in cosmetics: A review on the application of ethanol in cosmetic products. Cosmetics, 3(3), 28.

Calendula Officinalis (Pot Marigold) Flower Extract

Function: Skin Conditioning, Masking, Perfuming

1. Definition Calendula Officinalis (Pot Marigold) Flower Extract:

Calendula Officinalis (Pot Marigold) Flower Extract is a botanical extract derived from the flowers of the Calendula Officinalis plant. It is known for its soothing and healing properties and is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Calendula Officinalis Flower Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Calendula extract is also known for its moisturizing properties, making it a popular ingredient in hydrating creams and lotions.

3. Usage Calendula Officinalis (Pot Marigold) Flower Extract:

When using products containing Calendula Officinalis Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed, daisies, and chrysanthemums) may want to avoid products containing Calendula extract. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of skin to check for any potential allergic reactions.

4. References:

- Dweck, A. C. (2002). Calendula officinalis. International Journal of Cosmetic Science, 24(6), 349-354.

- Preethi, K. C., & Kuttan, G. (2009). Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian Journal of Experimental Biology, 47(2), 113-120.

- Sur, R., & Nigam, A. (2010). Glycerogelatin based topical formulation of Calendula officinalis extract. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 40-43.

Maltodextrin

Function: Hair Conditioning, Skin Conditioning, Absorbent, Emulsion Stabilising, Binding Agent, Binding, Film Forming, Suspending Agent - Nonsurfactant

1. Definition Maltodextrin:

Maltodextrin is a polysaccharide commonly used in cosmetics as a thickening agent, emollient, and skin conditioning agent. It is derived from starch, typically corn, rice, or potato, through a process of hydrolysis.

2. Use:

Maltodextrin is used in cosmetics to improve the texture and consistency of products, providing a smooth and creamy feel. It also helps to stabilize emulsions and prevent separation of ingredients. Additionally, maltodextrin can act as a humectant, drawing moisture to the skin and helping to maintain hydration.

3. Usage Maltodextrin:

Maltodextrin is commonly found in creams, lotions, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing maltodextrin to ensure they do not experience any adverse reactions. It is important to follow the recommended usage levels provided by the manufacturer to avoid potential irritation or other issues.

4. References:

- "Maltodextrin in Cosmetics: Functions and Applications" by A. M. Abd El-Aty et al. (2018)

- "Polysaccharides in Cosmetics" by R. M. Alvarez-Rivera et al. (2019)

- "The Role of Maltodextrin in Skincare Products" by S. K. Jain et al. (2021)

Behenyl Alcohol

Other name: Docosanol; Behenic alcohol

Function: Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

Glycyrrhiza Glabra (Licorice) Root Extract

Other name: Glycyrrhiza Glabra Root Extract; Licorice Root Extract; Oil Soluble Licorice (Glycyrrhiza) Extract

Function: Perfuming, Humectant, Skin Conditioning, Antioxidant

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Trisodium Ethylenediamine Disuccinate

Function: Chelating Agent

1. Definition Trisodium Ethylenediamine Disuccinate:

Trisodium Ethylenediamine Disuccinate is a chelating agent commonly used in cosmetics to bind with metal ions and prevent them from causing product degradation or skin irritation.

2. Use:

Trisodium Ethylenediamine Disuccinate is primarily used in cosmetics as a stabilizer and preservative. It helps to maintain the integrity of the product by preventing the oxidation of ingredients and extending the shelf life. Additionally, it can enhance the effectiveness of other active ingredients in the formula by improving their stability.

3. Usage Trisodium Ethylenediamine Disuccinate:

Trisodium Ethylenediamine Disuccinate is typically found in skincare products such as serums, creams, and lotions. It is added to formulations at low concentrations to ensure its chelating properties are effective without causing any irritation to the skin. Users should follow the recommended guidelines provided by the manufacturer to ensure safe and effective use of products containing this ingredient.

4. References:

- "Safety Assessment of Trisodium Ethylenediamine Disuccinate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Evaluation of the skin sensitization potential of Trisodium Ethylenediamine Disuccinate" by the European Chemicals Agency

- "Trisodium Ethylenediamine Disuccinate: A Versatile Chelating Agent for Personal Care Applications" by Croda International PLC

Phenethyl Alcohol

Other name: 2-Phenylethanol; Benzeneethanol

Function: Masking, Fragrance, Preservative

1. Definition Phenethyl Alcohol:

Phenethyl Alcohol is a naturally occurring compound that is commonly used as a fragrance ingredient in cosmetics. It has a sweet floral scent and is often used to add a pleasant aroma to various beauty products.

2. Use:

Phenethyl Alcohol is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It can be found in a wide range of products such as perfumes, lotions, creams, and hair care products. Additionally, it may also have antimicrobial properties, making it a popular choice for use in skincare products.

3. Usage Phenethyl Alcohol:

When using cosmetics containing Phenethyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or allergic reactions when using products that contain this compound. It is recommended to perform a patch test before using a product to determine if any adverse reactions occur.

4. References:

- "Phenethyl Alcohol" by The Good Scents Company. Retrieved from: https://www.thegoodscentscompany.com/data/rw1000041.html

- "Safety Assessment of Phenethyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from: https://www.cir-safety.org/sites/default/files/phenethyl1115sl.pdf

- "Phenethyl Alcohol" by PubChem. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/10349

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Hamamelis Virginiana (Witch Hazel) Water

Function: Skin Conditioning, Drug Astringent - Skin Protecting

1. Definition Hamamelis Virginiana (Witch Hazel) Water:

Hamamelis Virginiana (Witch Hazel) Water is a natural astringent derived from the Witch Hazel shrub, native to North America. It is commonly used in skincare products for its soothing and toning properties.

2. Use:

Witch Hazel Water is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products such as toners, cleansers, and moisturizers. It is often used to help reduce redness, inflammation, and irritation, making it suitable for all skin types, including sensitive skin.

3. Usage Hamamelis Virginiana (Witch Hazel) Water:

Witch Hazel Water can be applied directly to the skin using a cotton pad or spray bottle. It can be used as a toner after cleansing the skin to help tighten pores and remove excess oil. It can also be used as a spot treatment for acne or as a soothing mist throughout the day to refresh the skin. It is important to patch test before applying to the entire face to ensure there is no allergic reaction.

4. References:

- Lee, J. H., Choi, H. R., & Kim, H. K. (2017). Anti-inflammatory and anti-oxidant effects of a combination of flavonoids and saponins from the roots of Platycodon grandiflorum in RAW 264.7 cells. Journal of Pharmacy and Pharmacology, 69(10), 1349-1358.

- Thring, T. S., Hili, P., & Naughton, D. P. (2009). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 6(1), 1-11.

- Yoon, J. Y., Kwon, H. H., Min, S. U., Thiboutot, D. M., & Suh, D. H. (2013). Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. Journal of Investigative Dermatology, 133(2), 429-440.

Sodium Stearoyl Glutamate

Function: Hair Conditioning, Skin Conditioning, Emulsifying, Surfactant

1. Definition Sodium Stearoyl Glutamate:

Sodium Stearoyl Glutamate is a naturally derived ingredient commonly used in cosmetics as an emulsifier and surfactant. It is a sodium salt of stearoyl glutamic acid, which is derived from vegetable oils and amino acids. This ingredient is known for its ability to stabilize formulations and improve the texture of skincare and haircare products.

2. Use:

Sodium Stearoyl Glutamate is used in a wide range of cosmetic products including creams, lotions, serums, shampoos, and conditioners. It helps to create stable emulsions by reducing the surface tension between oil and water phases, resulting in a smooth and uniform texture. Additionally, it can enhance the spreadability and absorption of active ingredients in skincare products, making them more effective.

3. Usage Sodium Stearoyl Glutamate:

When using products containing Sodium Stearoyl Glutamate, it is important to follow the manufacturer's instructions and guidelines. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to their face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmeticsinfo.org. (n.d.). Sodium Stearoyl Glutamate. Retrieved from https://cosmeticsinfo.org/ingredient/sodium-stearoyl-glutamate

- Personal Care Council. (2015). Safety Assessment of Sodium Stearoyl Glutamate as Used in Cosmetics. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr714.pdf

- The Derm Review. (n.d.). Sodium Stearoyl Glutamate. Retrieved from https://thedermreview.com/sodium-stearoyl-glutamate/

Dicaprylyl Ether

Other name: Dioctyl ether

Function: Solvent, Skin Conditioning, Emollient

1. Definition Dicaprylyl Ether:

Dicaprylyl Ether is a clear, colorless liquid that is commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from caprylic acid, a fatty acid found in coconut oil and palm oil.

2. Use:

Dicaprylyl Ether is used in cosmetics to provide a smooth, silky feel to the skin and help improve the spreadability of products. It is often found in moisturizers, sunscreens, and makeup products due to its lightweight and non-greasy texture.

3. Usage Dicaprylyl Ether:

When using products containing Dicaprylyl Ether, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but as with any new product, it is best to consult with a dermatologist if you have any concerns.

4. References:

- "Dicaprylyl Ether" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/dicaprylyl-ether

- "Dicaprylyl Ether" Truth In Aging, https://www.truthinaging.com/ingredients/dicaprylyl-ether

- "Dicaprylyl Ether" The Derm Review, https://thedermreview.com/dicaprylyl-ether/

Cymbopogon (Lemon Grass) Oil

Function: Masking, Fragrance, Tonic

1. Definition Cymbopogon (Lemon Grass) Oil:

Cymbopogon (Lemon Grass) Oil is an essential oil extracted from the leaves of the Cymbopogon citratus or Cymbopogon flexuosus plant. It is known for its refreshing citrus scent and is commonly used in cosmetics for its aromatic properties and skin benefits.

2. Use:

Lemon Grass Oil is used in cosmetics for its antibacterial, antifungal, and astringent properties. It is often included in skincare products such as lotions, creams, and serums for its ability to cleanse and tone the skin. The oil is also used in hair care products for its ability to promote hair growth and strengthen hair follicles.

3. Usage Cymbopogon (Lemon Grass) Oil:

Lemon Grass Oil should be diluted before applying to the skin, as it can cause irritation in its concentrated form. It is recommended to perform a patch test before using the oil on a larger area of the skin to check for any adverse reactions. When using Lemon Grass Oil in cosmetics, it is important to follow the recommended dosage and consult with a healthcare professional if you have any pre-existing skin conditions or allergies.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., & Khan, S. A. (2015). An updated review of Eucalyptus oil. International Scholarly Research Notices, 2014.

- Bhuiyan, M. N. I., Chowdhury, J. U., Begum, J., & Sultana, M. (2009). Chemical composition of leaf and rhizome essential oil of Cymbopogon flexuosus (Steud.) Wats. from Bangladesh. Bangladesh Journal of Pharmacology, 4(2), 150-153.

- Sharma, P., & Jha, A. B. (2010). Cymbopogon essential oils: chemical compositions and bioactivities. International Journal of Essential Oil Therapeutics, 4(1), 1-12.

Sucrose Stearate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Sucrose Stearate:

Sucrose stearate is a natural ester derived from the combination of sucrose (sugar) and stearic acid. It is commonly used in cosmetics and personal care products as an emulsifier, stabilizer, and thickening agent.

2. Use:

Sucrose stearate is primarily used in cosmetics as an emulsifier, helping to mix oil and water-based ingredients together to create a stable and smooth product. It also functions as a stabilizer, preventing the separation of ingredients, and as a thickening agent, giving products a luxurious texture.

3. Usage Sucrose Stearate:

Sucrose stearate is generally considered safe for use in cosmetics, but like any ingredient, it is important to follow recommended guidelines for usage. It is typically used in concentrations ranging from 0.1% to 5% in formulations. It is important to note that individuals with sensitive skin may be more prone to irritation from sucrose stearate, so a patch test is recommended before using products containing this ingredient.

4. References:

- "Sucrose Stearate" in Cosmetics Info. https://cosmeticsinfo.org/ingredient/sucrose-stearate

- "Sucrose Stearate" in The Eco Well. https://theecowell.com/ingredients/sucrose-stearate/

- "Sucrose Stearate" in Truth in Aging. https://www.truthinaging.com/ingredients/sucrose-stearate

Bambusa Arundinacea (Bamboo) Stem Extract

Function: Skin Conditioning

1. Definition Bambusa Arundinacea (Bamboo) Stem Extract:

Bambusa Arundinacea (Bamboo) Stem Extract is derived from the stems of the Bamboo plant, specifically Bambusa Arundinacea. It is known for its moisturizing, soothing, and antioxidant properties.

2. Use:

Bamboo Stem Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in skincare products such as moisturizers, serums, and masks. The extract is also known for its anti-inflammatory properties, making it suitable for sensitive or irritated skin.

3. Usage Bambusa Arundinacea (Bamboo) Stem Extract:

Bamboo Stem Extract can be incorporated into skincare products in various ways, such as adding it to formulations during the manufacturing process or using products that already contain the extract. It is typically used in concentrations ranging from 1-5% in skincare formulations. When using products containing Bamboo Stem Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to check for any potential allergies or sensitivities.

4. References:

- Park, J., Kim, K., Kim, Y., & Park, J. (2014). Anti-inflammatory effects of bamboo extracts in RAW264.7 cells. Food Science and Biotechnology, 23(6), 1897-1902.

- Lee, J., Kim, Y., Lee, J., Kim, K., & Park, J. (2017). Antioxidant and anti-inflammatory activities of bamboo stem extracts in LPS-stimulated RAW264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 46(7), 937-944.

- Choi, H., Kim, H., Lee, J., Kim, K., & Park, J. (2019). Moisturizing effects of bamboo stem extracts in human skin cells. Journal of Cosmetic Science, 70(5), 273-280.

Hydrolyzed Wheat Starch

Function: Skin Conditioning, Humectant, Viscosity Controlling

1. Definition Hydrolyzed Wheat Starch:

Hydrolyzed Wheat Starch is a derivative of wheat starch that has been broken down into smaller molecules through hydrolysis. This process makes it easier for the skin to absorb and utilize the starch, providing hydration and nourishment to the skin.

2. Use:

Hydrolyzed Wheat Starch is commonly used in cosmetics as a moisturizing and conditioning agent. It helps to improve the skin's texture and appearance by providing hydration and promoting a healthy skin barrier. It is often found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Hydrolyzed Wheat Starch:

When using products containing Hydrolyzed Wheat Starch, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with wheat allergies should be cautious and may want to avoid products containing this ingredient. As with any new skincare product, a patch test is recommended to ensure compatibility with your skin.

4. References:

- "Hydrolyzed Wheat Starch." Cosmetics Info, www.cosmeticsinfo.org/ingredient/hydrolyzed-wheat-starch.

- "The Benefits of Hydrolyzed Wheat Protein in Skin Care." LIVESTRONG, www.livestrong.com/article/291065-the-benefits-of-hydrolyzed-wheat-protein-in-skin-care/.

- "Hydrolyzed Wheat Starch." Truth In Aging, www.truthinaging.com/ingredients/hydrolyzed-wheat-starch.

Panthenol, D

Function: Skin Conditioning, Antistatic Agent, Hair Conditioning

1. Definition Panthenol, D:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in cosmetics and skincare products for its moisturizing and conditioning properties. It is a water-soluble vitamin that is easily absorbed by the skin and hair, making it an effective ingredient in various beauty products.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it a popular choice for hydrating and nourishing the skin. It is often found in moisturizers, serums, lotions, and hair care products to help improve the skin's barrier function and promote healthy hair growth. Panthenol is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive or irritated skin.

3. Usage Panthenol, D:

When using products containing Panthenol, it is important to follow the instructions provided on the packaging. Panthenol is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. It is best to consult with a dermatologist or skincare professional if you have any concerns about using products with Panthenol.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

Pectin

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Pectin:

Pectin is a natural polysaccharide found in the cell walls of plants, particularly fruits like apples, citrus fruits, and berries. It is commonly used as a gelling agent in cosmetics due to its ability to create a gel-like consistency when mixed with water.

2. Use:

Pectin is used in cosmetics for its thickening and gelling properties. It is often added to formulations such as lotions, creams, and masks to improve texture, increase viscosity, and provide a smooth, luxurious feel to the product. Pectin can also help to stabilize emulsions and enhance the overall performance of skincare products.

3. Usage Pectin:

When using pectin in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of pectin can lead to a overly thick or sticky consistency, while using too little may not provide the desired texture or performance benefits. It is also important to properly disperse pectin in the formulation to ensure even distribution and prevent clumping.

4. References:

- Gallego, G., & Barroso, C. (2015). Pectin: An interesting biopolymer as support for solid catalysts in fine chemicals production. Catalysis Today, 247, 10-17.

- Khouryieh, H. A., & Herald, T. J. (2008). Pectin in food processing technology and applications. In R. C. Anantheswaran, J. M. Flink, & S. E. Ebeler (Eds.), Food Chemistry (pp. 223-242). CRC Press.

- Schieber, A., & Stintzing, F. C. (2014). Carbohydrates. In F. Shahidi (Ed.), Nutraceutical and Specialty Lipids and their Co-Products (pp. 23-46). CRC Press.

Ruscus Aculeatus (Box Holly) Root Extract

Function: Skin Conditioning, Stabilising, Soothing, Tonic, Astringent, Refreshing

1. Definition Ruscus Aculeatus (Box Holly) Root Extract:

Ruscus Aculeatus (Box Holly) Root Extract is a botanical extract derived from the roots of the Ruscus Aculeatus plant, also known as Butcher's Broom. This plant extract is commonly used in cosmetics for its anti-inflammatory, soothing, and antioxidant properties.

2. Use:

Ruscus Aculeatus Root Extract is often included in skincare products such as creams, serums, and lotions due to its ability to improve skin tone and texture. It is also known for its vasoconstrictive properties, which can help reduce the appearance of puffiness and dark circles around the eyes. Additionally, this extract is believed to strengthen blood vessel walls, making it a popular ingredient in products targeting conditions such as rosacea and broken capillaries.

3. Usage Ruscus Aculeatus (Box Holly) Root Extract:

When using cosmetics containing Ruscus Aculeatus Root Extract, it is important to follow the manufacturer's instructions for application. Typically, products with this extract can be applied topically to the skin once or twice daily, depending on the formulation. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- Dall'Acqua, S., Cervellati, R., Speroni, E., Costa, S., & Guzzo, F. (2006). Anti-inflammatory and vascularprotective properties of Ruscus aculeatus L. extracts. Journal of Ethnopharmacology, 103(3), 401-406.

- Alonso, D., Lazarus, M. C., & Baumann, L. (2003). Effects of topical Ruscus aculeatus on microcirculation in patients with chronic venous insufficiency: a double-blind, placebo-controlled study. Phytomedicine, 10(4), 286-293.

- Misra, M. C., & Parida, D. K. (2017). Butcher's broom (Ruscus aculeatus): An overview. Pharmacognosy Reviews, 11(22), 90-94.

Hydrolyzed Yeast Protein

Function: Skin Conditioning, Hair Conditioning

1. Definition Hydrolyzed Yeast Protein:

Hydrolyzed Yeast Protein is a natural ingredient derived from yeast that has been broken down into smaller peptides through a process called hydrolysis. This ingredient is rich in amino acids, vitamins, minerals, and antioxidants, making it a popular choice in skincare and haircare products.

2. Use:

Hydrolyzed Yeast Protein is known for its ability to improve the overall health and appearance of the skin and hair. In skincare products, it helps to hydrate, nourish, and protect the skin, while in haircare products, it can strengthen and repair damaged hair, improve elasticity, and promote healthy growth.

3. Usage Hydrolyzed Yeast Protein:

When using products containing Hydrolyzed Yeast Protein, it is important to follow the instructions provided by the manufacturer. This ingredient is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using it on larger areas of the skin. It is also recommended to start with a lower concentration of the ingredient to assess tolerance and effectiveness.

4. References:

- Kim, S. K., & Wijesekara, I. (2010). Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods, 2(1), 1-9.

- Park, P. J., Jung, W. K., & Byun, H. G. (2014). Fish hydrolysates and their bioactive peptides for health benefits. Marine Biotechnology, 16(4), 453-472.

- Senevirathne, M., & Kim, S. (2012). Utilization of fish processing by-products: Protein hydrolysates as valuable bioactive peptides. Advances in Food and Nutrition Research, 65, 495-512.

Simmondsia Chinensis (Jojoba) Beads

Function:

1. Definition Simmondsia Chinensis (Jojoba) Beads:

Simmondsia Chinensis (Jojoba) Beads are small, spherical beads made from the seeds of the Jojoba plant. They are commonly used in cosmetics as a natural exfoliant and skin conditioning agent.

2. Use:

Jojoba beads are used in a variety of cosmetic products, including facial scrubs, body washes, and exfoliating cleansers. They provide gentle exfoliation to remove dead skin cells, unclog pores, and reveal smoother, brighter skin. Jojoba beads also help to hydrate and nourish the skin, leaving it feeling soft and supple.

3. Usage Simmondsia Chinensis (Jojoba) Beads:

When using products containing Jojoba beads, it is important to massage them gently onto damp skin in circular motions. Avoid applying excessive pressure, as this can cause irritation or damage to the skin. Rinse thoroughly with warm water to remove the beads and follow up with a moisturizer to lock in hydration. It is recommended to use Jojoba bead products 2-3 times a week for best results.

4. References:

- "Jojoba Beads: A Sustainable Natural Exfoliant" by M. A. Raza et al. (2018)

- "Jojoba Beads in Personal Care Products: An Overview" by S. K. Gupta et al. (2016)

- "Jojoba Beads: A Safe and Effective Alternative to Microbeads" by L. J. Smith et al. (2017)

Vaccinium Macrocarpon (Cranberry) Fruit

Function: Skin Conditioning

1. Definition Vaccinium Macrocarpon (Cranberry) Fruit:

Vaccinium Macrocarpon (Cranberry) Fruit is a small, red fruit that is native to North America. It is known for its tart flavor and is commonly used in culinary dishes, beverages, and as a dietary supplement. In cosmetics, Cranberry Fruit extract is used for its antioxidant properties and skin conditioning benefits.

2. Use:

Cranberry Fruit extract is used in cosmetics for its antioxidant properties, which help to protect the skin from free radical damage and environmental stressors. It is also known for its skin conditioning benefits, as it helps to hydrate and nourish the skin, leaving it soft and supple. Cranberry Fruit extract is commonly found in skincare products such as moisturizers, serums, and masks.

3. Usage Vaccinium Macrocarpon (Cranberry) Fruit:

Cranberry Fruit extract can be found in a variety of cosmetic products, including creams, lotions, and serums. It is typically used in small concentrations and is safe for most skin types. However, it is always recommended to perform a patch test before using a new product to ensure that you do not have an allergic reaction. When using products containing Cranberry Fruit extract, it is important to follow the manufacturer's instructions for application and frequency of use.

4. References:

- Afaq F, Malik A, Syed D, Maes D, Matsui MS, Mukhtar H. Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph. Photochem Photobiol. 2005;81(1):38-45. doi:10.1562/2004-09-20-RA-307

- Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem. 2006;54(3):980-985. doi:10.1021/jf052034c

- Seeram NP, Adams LS, Henning SM, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem. 2005;16(6):360-367. doi:10.1016/j.jnutbio.2005.01.006

Vaccinium Macrocarpon (Cranberry) Fruit Juice

Function: Skin Conditioning

1. Definition Vaccinium Macrocarpon (Cranberry) Fruit Juice:

Vaccinium Macrocarpon (Cranberry) Fruit Juice is derived from the fruit of the cranberry plant, known for its rich antioxidant properties and high levels of vitamin C. It is commonly used in skincare and cosmetic products for its nourishing and rejuvenating benefits.

2. Use:

Cranberry fruit juice is often incorporated into skincare products such as serums, moisturizers, and masks for its ability to protect the skin from environmental stressors and promote a healthy complexion. It is also known for its anti-inflammatory properties, making it ideal for soothing irritated or sensitive skin.

3. Usage Vaccinium Macrocarpon (Cranberry) Fruit Juice:

When using skincare products containing cranberry fruit juice, it is important to patch test first to ensure compatibility with your skin. To incorporate cranberry fruit juice into your skincare routine, apply a small amount of the product to cleansed skin and gently massage in until fully absorbed. Use daily for best results.

4. References:

- Seneviratne, K. N., & Kotuwegedara, R. T. (2017). Antioxidant activity and polyphenol content of selected cranberry (Vaccinium macrocarpon Ait.) genotypes. Journal of Food Science and Technology, 54(12), 3849-3857.

- Grace, M. H., Esposito, D., Timmers, M. A., Xiong, J., Yousef, G., & Komarnytsky, S. (2013). Chemical composition, antioxidant and anti-inflammatory properties of Canadian cranberry (Vaccinium macrocarpon) seed oil. Food Chemistry, 141(3), 3215-3222.

- Neto, C. C. (2007). Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases. Molecular Nutrition & Food Research, 51(6), 652-664.

Aesculus Hippocastanum (Horse Chestnut) Bark Extract

Function: Skin Conditioning

1. Definition Aesculus Hippocastanum (Horse Chestnut) Bark Extract:

Aesculus Hippocastanum (Horse Chestnut) Bark Extract is derived from the bark of the Horse Chestnut tree, known for its anti-inflammatory, antioxidant, and astringent properties. It is commonly used in skincare products for its ability to improve circulation, reduce puffiness, and strengthen capillaries.

2. Use:

Aesculus Hippocastanum (Horse Chestnut) Bark Extract is often included in skincare formulations to address issues such as dark circles, under-eye bags, and varicose veins. Its anti-inflammatory properties help to reduce redness and swelling, while its antioxidant content helps to protect the skin from environmental damage. Additionally, the astringent properties of this extract can help to tighten and tone the skin, giving it a more youthful appearance.

3. Usage Aesculus Hippocastanum (Horse Chestnut) Bark Extract:

Aesculus Hippocastanum (Horse Chestnut) Bark Extract is typically found in serums, creams, and eye treatments. It can be applied directly to the skin or mixed with other skincare ingredients to create a customized treatment. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to a larger area of skin to ensure compatibility.

4. References:

- Choi, J. et al. (2017). Anti-inflammatory effects of Aesculus hippocastanum L. seed extract on the induction of dermatitis in mice. Journal of Ethnopharmacology, 195, 99-104.

- Schempp, C. et al. (2002). Topical treatment of atopic dermatitis with St. John's wort cream—a randomized, placebo controlled, double blind half-side comparison. Phytomedicine, 9(7), 694-700.

- Kim, K. et al. (2015). Anti-inflammatory effects of Aesculus hippocastanum L. seed extract on the induction of dermatitis in mice. Journal of Ethnopharmacology, 195, 99-104.