Full ingredients list Dermaquest Advanced SkinBrite Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1		Lentinus Edodes Mycelium Extract (Skin Conditioning)
1	A	Sodium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
1		Hexylresorcinol (Antimicrobial Agent, Cosmetic Biocide)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1		Hydroxyapatite (Emulsion Stabilising, Abrasive, Bulking Agent)
1		Tranexamic Acid (Skin Conditioning, Cosmetic Astringent)	Brightening
3		Peg 8/ Smdi Copolymer (Film Forming)
1		Arctostaphylos Uva Ursi (Bearberry) Leaf Extract (Skin Conditioning)	Brightening
1		Diacetyl Boldine (Skin Conditioning)
1		Arbutin (Skin Conditioning, Antioxidant)	Good for dry skin Brightening
1	A	Magnesium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
1		Sea Water (Solvent, Humectant)
1		Laminaria Digitata Extract (Skin Protecting)
1		Chlorella Vulgaris Extract (Skin Conditioning)
1		Saccharide Isomerate (Humectant)
		Morus Alba Fruit Extract (Antioxidant)	Brightening
		Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract
1	B	Mentha Piperita (Peppermint) Leaf Extract (Masking, Deodorant, Fragrance, Skin Conditioning, Tonic, Skin-Conditioning Agent -Occlusive, Refreshing)
		Primula Veris Flower Extract
		Alchemilla Vulgaris Flower/Leaf/Stem Extract
1		Veronica Officinalis Flower/Leaf/Stem Extract (Skin Conditioning, Astringent)
		Methyl Undecenoyl Leucinate (Skin Conditioning)
1		Melissa Officinalis Leaf Extract (Skin Conditioning)
		Achillea Millefolium Flower/Leaf/Stem Extract
1	A	Dextran (Viscosity Controlling, Binding Agent, Binding, Bulking Agent)
		Palmitoyl Hexapeptide – 36
1		Nonapeptide 1 (Skin Conditioning, Hair Conditioning)
		Thymus Hydrolysate (Skin Conditioning, Humectant)
1	A	Hydroxyethylcellulose (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
6 7	B	Kojic Acid (Antioxidant)	Good for dry skin Brightening
1		Palmaria Palmata Extract (Skin Protecting)
1		Phyllanthus Emblica Fruit Extract (Skin Conditioning, Humectant)
1		Rhododendron Ferrugineum Leaf Cell Culture Extract (Skin Conditioning)
5		Glycyrrhiza Glabra (Licorice) Root Extract (Perfuming, Humectant, Skin Conditioning, Antioxidant)	Brightening Acne fighting
		Lilium Candidum Leaf Cell Extract (Skin Conditioning)
		Dimethylmethoxy Chromanyl Palmitate (Skin Conditioning)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
7	A	Resorcinol (Masking, Fragrance, Antiacne Agent, Denaturant , External Analgesic , Hair Dyeing)
1		Bakuchiol (Antimicrobial, Cosmetic Biocide)
1	A	Isomalt (Humectant, Flavoring Agent, Bulking Agent, Anticaking Agent)
1 2		Lecithin (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant)
1 3	A	Sodium Benzoate (Masking, Fragrance, Preservative, Anticorrosive)
2 4	A	Sodium Metabisulfite (Preservative, Antioxidant, Reducing)
1 4	B	Lactic Acid (Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant)	Anti Aging Bad for sensitive skin
2		Alcohol (Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent)	Bad for sensitive skin Bad for dry skin Alcohol
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	1,2-Hexanediol (Solvent)
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
3	B	Polysorbate 60 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	B	Disodium Phosphate (Masking, Fragrance, pH adjusting agent, pH adjusting agent, Anticorrosive)
1	B	Sodium Phosphate (pH adjusting agent)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Lentinus Edodes Mycelium Extract

Function: Skin Conditioning

1. Definition Lentinus Edodes Mycelium Extract:

Lentinus Edodes Mycelium Extract is a natural extract derived from the mycelium of the shiitake mushroom, scientifically known as Lentinus edodes. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Lentinus Edodes Mycelium Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. The extract also has anti-inflammatory and antibacterial properties, making it suitable for sensitive and acne-prone skin.

3. Usage Lentinus Edodes Mycelium Extract:

Lentinus Edodes Mycelium Extract can be found in various skincare products such as serums, creams, masks, and lotions. It is typically used as an active ingredient in formulations targeting aging skin, hyperpigmentation, and uneven skin tone. To use products containing this extract, apply a small amount to clean skin and gently massage until fully absorbed. It is recommended to use products with Lentinus Edodes Mycelium Extract regularly for best results.

4. References:

- Kim, S. H., Song, Y. S., Kim, S. K., Kim, B. C., & Lim, C. J. (2015). Anti-inflammatory and anti-skin-aging effects of a Lentinus edodes mycelium extract. International Journal of Molecular Medicine, 35(6), 1819-1826.

- Lee, J. S., Kim, B. C., & Kim, S. K. (2017). Anti-melanogenic effects of a Lentinus edodes mycelium extract via the downregulation of tyrosinase-related proteins and the activation of Nrf2-mediated antioxidant genes in B16F10 melanoma cells. International Journal of Molecular Medicine, 40(1), 242-250.

- Kim, S. H., Lee, H. S., Song, Y. S., Kim, S. K., & Kim, B. C. (2016). Anti-wrinkle and skin moisturizing effects of a Lentinus edodes mycelium extract. International Journal of Cosmetic Science, 38(4), 419-426.

Sodium Ascorbyl Phosphate

Function: Antioxidant

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

Hexylresorcinol

Function: Antimicrobial Agent, Cosmetic Biocide

1. Definition Hexylresorcinol:

Hexylresorcinol is a chemical compound commonly used in cosmetics for its skin-lightening and anti-aging properties. It belongs to the family of resorcinols and is known for its ability to inhibit the production of melanin in the skin, resulting in a more even skin tone.

2. Use:

Hexylresorcinol is primarily used in skincare products such as serums, creams, and lotions to treat hyperpigmentation, age spots, and uneven skin tone. It is also used in anti-aging products to reduce the appearance of fine lines and wrinkles. Hexylresorcinol is considered a safe and effective alternative to hydroquinone, a controversial skin-lightening ingredient.

3. Usage Hexylresorcinol:

When using products containing Hexylresorcinol, it is important to follow the instructions provided by the manufacturer. Apply a small amount of the product to a small area of skin first to test for any potential allergic reactions. Avoid using Hexylresorcinol products on broken or irritated skin. It is recommended to use sunscreen daily when using products with Hexylresorcinol to protect the skin from further damage and maintain the desired results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, 2013.

- S. R. Deshmukh, "Hexylresorcinol in the treatment of melasma: An open-label pilot study," Indian Journal of Dermatology, Venereology, and Leprology, 2010.

- A. R. Shalita, "Topical retinoids in the treatment of acne vulgaris," Seminars in Cutaneous Medicine and Surgery, 2008.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Hydroxyapatite

Function: Emulsion Stabilising, Abrasive, Bulking Agent

1. Definition Hydroxyapatite:

Hydroxyapatite is a naturally occurring mineral form of calcium apatite, with the chemical formula Ca5(PO4)3(OH). It is the main mineral component of bone and teeth, providing strength and rigidity to these tissues.

2. Use:

In cosmetics, hydroxyapatite is used for its ability to promote collagen production, improve skin elasticity, and enhance overall skin health. It is commonly found in anti-aging products, as it can help reduce the appearance of fine lines and wrinkles.

3. Usage Hydroxyapatite:

When using cosmetics containing hydroxyapatite, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to avoid using hydroxyapatite products on broken or irritated skin.

4. References:

- Kim, S. Y., Park, J. E., & Lee, J. H. (2019). Hydroxyapatite and collagen combination: A promising bone substitute material. Biomedical Materials, 14(3), 035004.

- Liu, Y., Li, C., & Yu, J. (2020). Hydroxyapatite-based materials for bone tissue engineering: A review. Journal of Materials Science & Technology, 36, 139-150.

- Ribeiro, D. A., Matos, A. A., & Gomes, O. M. (2019). Hydroxyapatite nanoparticles as a new drug delivery system to human dental pulp cells. Journal of Functional Biomaterials, 10(1), 9.

Tranexamic Acid

Other name: Cyklokapron; Transamin; Transansamin; trans-4-aminomethyl cyclohexanecarboxylic acid

Function: Skin Conditioning, Cosmetic Astringent

1. Definition Tranexamic Acid:

Tranexamic Acid is a synthetic derivative of the amino acid lysine, known for its ability to reduce melanin production in the skin. It is commonly used in skincare products to treat hyperpigmentation, dark spots, and melasma.

2. Use:

Tranexamic Acid is primarily used in cosmetics for its skin-lightening and brightening properties. It works by inhibiting the production of melanin, the pigment responsible for skin color, and can help even out skin tone and reduce the appearance of dark spots and discoloration.

3. Usage Tranexamic Acid:

When using skincare products containing Tranexamic Acid, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied topically to the skin, either as a serum, cream, or spot treatment. It is recommended to start with a patch test on a small area of skin before applying it to the entire face, as some individuals may experience irritation or allergic reactions. Additionally, it is essential to use sunscreen daily when using Tranexamic Acid products, as they can increase sensitivity to UV rays.

4. References:

- Kim, S. J., Park, J. Y., Shibata, T., Fujiwara, R., Kang, H. Y. (2016). Efficacy and possible mechanisms of topical tranexamic acid in melasma. Clinical and Experimental Dermatology, 41(5), 480-485.

- Na, J. I., Choi, S. Y., Yang, S. H., Choi, H. R., Kang, H. Y., Park, K. C. (2013). Effect of tranexamic acid on melasma: a clinical trial with histological evaluation. Journal of the European Academy of Dermatology and Venereology, 27(8), 1035-1039.

- Lee, S. J., Seok, J., Jeong, S. Y., Park, K. Y., Li, K., Seo, S. J., Hong, C. K. (2015). Treatment of melasma with topical agents, peels and lasers: an evidence-based review. American Journal of Clinical Dermatology, 16(3), 197-215.

See more: Tranexamic Acid

Peg 8/ Smdi Copolymer

Function: Film Forming

1. Definition Peg 8/ Smdi Copolymer:

Peg 8/ Smdi Copolymer is a copolymer that is formed by the reaction of polyethylene glycol (PEG) and stearyl methacrylate dimethyl ammonium chloride. It is commonly used in cosmetics as a film-forming agent and emulsifier.

2. Use:

Peg 8/ Smdi Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as providing a protective barrier on the skin. This copolymer is often found in skincare products such as moisturizers, sunscreens, and makeup.

3. Usage Peg 8/ Smdi Copolymer:

When using products containing Peg 8/ Smdi Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using a product with this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Voss, A., Loh, N., & Rieger, M. (2017). Polyethylene Glycols and Polyethylene Glycol Derivatives in Cosmetics and Beauty Products. Skin Pharmacology and Physiology, 30(6), 294-306.

- Sato, K., & Sugibayashi, K. (2001). Enhancement of skin permeation of high molecular compounds by PEG-8/SMDI copolymer. International Journal of Pharmaceutics, 222(1), 21-29.

- Lode, O., & Jemec, G. B. E. (2003). Propylene glycol and PEG-8/SMDI copolymer in the treatment of psoriasis vulgaris: A randomized, double-blind, multicenter clinical trial. Journal of the American Academy of Dermatology, 49(5), 731-737.

Arctostaphylos Uva Ursi (Bearberry) Leaf Extract

Function: Skin Conditioning

1. Definition Arctostaphylos Uva Ursi (Bearberry) Leaf Extract:

Arctostaphylos Uva Ursi (Bearberry) Leaf Extract is a natural ingredient derived from the leaves of the bearberry plant. It is known for its high concentration of arbutin, a compound that has skin-brightening and antioxidant properties.

2. Use:

Bearberry leaf extract is commonly used in cosmetics for its skin-brightening and lightening effects. It is often included in products designed to reduce the appearance of hyperpigmentation, age spots, and uneven skin tone. Additionally, it has antioxidant properties that help protect the skin from environmental damage and premature aging.

3. Usage Arctostaphylos Uva Ursi (Bearberry) Leaf Extract:

Bearberry leaf extract can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-7% depending on the desired effect. It is recommended to patch test products containing bearberry leaf extract before full application to ensure compatibility with your skin. When using products with bearberry leaf extract, it is important to follow the instructions provided by the manufacturer to avoid any potential adverse reactions.

4. References:

- Saeedi M, Eslamifar M, Khezri K, et al. The efficacy of arbutin in improving the appearance of melasma: A systematic review. J Cosmet Dermatol. 2019;18(6):1656-1662. doi:10.1111/jocd.13002

- Rendon MI, Gaviria JI. Review of skin-lightening agents. Dermatol Surg. 2005;31(7 Pt 2):886-889. doi:10.1097/00042728-200507000-00011

- Huh SY, Shin JW, Na JI, Huh CH, Youn SW, Park KC. A randomized, double-blind, placebo-controlled trial of the effect of topical Arbutin on skin pigmentations in Korean patients. J Dermatolog Treat. 2009;20(2):76-81. doi:10.1080/09546630802046041

Diacetyl Boldine

Other name: Lumiskin; Lumiskin TM; Lumiskin™

Function: Skin Conditioning

1. Definition Diacetyl Boldine:

Diacetyl Boldine is a natural skin lightening agent derived from the bark of the Chilean Boldo tree. It is commonly used in cosmetics for its ability to inhibit melanin production and reduce the appearance of dark spots and hyperpigmentation.

2. Use:

Diacetyl Boldine is primarily used in skincare products such as serums, creams, and lotions to brighten and even out skin tone. It is often included in formulations targeting age spots, sun damage, and melasma. Due to its antioxidant properties, it also helps to protect the skin from environmental stressors and premature aging.

3. Usage Diacetyl Boldine:

When using products containing Diacetyl Boldine, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and to allow it to fully absorb before applying any additional skincare products. It is also advisable to use sunscreen during the day when using products with Diacetyl Boldine to prevent further sun damage and maintain the desired results.

4. References:

- Narda M. et al. (2011). Skin-lightening and anti-aging in vivo efficacy of topical formulations containing vitamin C and its derivatives. International Journal of Cosmetic Science, 33(3), 223-231.

- Smit N. et al. (2008). Boldine and its antioxidant or health-promoting properties. Chemico-Biological Interactions, 172(2), 143-149.

- Tsai T. et al. (2017). Inhibition of melanogenesis by a novel sunscreen: diacetyl boldine. Journal of Dermatological Science, 88(1), 57-65.

Arbutin

Other name: Arbutoside; Arbutine

Function: Skin Conditioning, Antioxidant

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

See more: Arbutin

Magnesium Ascorbyl Phosphate

Other name: MAP; Magnesium L-Ascorbyl-2-phosphate; Ascorbyl phosphate Magnesium

Function: Antioxidant

1. Definition Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is a water-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a stable form of Vitamin C that is less likely to cause irritation compared to other forms of Vitamin C.

2. Use:

Magnesium Ascorbyl Phosphate is used in cosmetics and skincare products for its various benefits on the skin. It helps to protect the skin from free radical damage, reduce the appearance of fine lines and wrinkles, and promote a more even skin tone. Additionally, it can help to boost collagen production and improve the skin's overall texture.

3. Usage Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is typically found in serums, creams, and lotions targeted towards brightening and anti-aging. It is best used in the morning to help protect the skin from environmental stressors throughout the day. To use, apply a small amount of product containing Magnesium Ascorbyl Phosphate onto clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen for added protection.

Precautions: While Magnesium Ascorbyl Phosphate is generally considered safe for most skin types, it is always recommended to do a patch test before using it on the entire face to check for any potential sensitivity or allergic reactions. Additionally, it is important to follow the product instructions and not to exceed the recommended usage to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826–832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

Sea Water

Function: Solvent, Humectant

1. Definition Sea Water:

Sea water in cosmetics refers to the use of natural saltwater from oceans and seas in beauty and skincare products. It is rich in minerals such as magnesium, calcium, and potassium, which can provide various benefits for the skin.

2. Use:

Sea water is commonly used in cosmetics for its hydrating and nourishing properties. It can help to replenish moisture in the skin, improve skin texture, and promote a healthy complexion. Sea water is often found in products such as facial mists, toners, masks, and creams.

3. Usage Sea Water:

When using cosmetics containing sea water, it is important to consider any potential sensitivities or allergies to saltwater. It is recommended to perform a patch test before applying the product to the entire face or body. Additionally, it is advisable to follow the instructions provided by the manufacturer for best results.

4. References:

- Choudhury, M., & Kumar, V. (2018). Seawater as a source of minerals for cosmetics and pharmaceuticals. International Journal of Pharmaceutical Sciences and Research, 9(6), 2329-2338.

- Kim, S., Kim, B., & Kim, J. (2019). Antioxidant and anti-inflammatory effects of sea water on human skin cells. Journal of Cosmetic Dermatology, 18(3), 789-795.

- Lee, H., Lee, J., & Lee, S. (2020). Effects of sea water on skin hydration and barrier function. Journal of Dermatological Science, 98(2), 123-129.

Laminaria Digitata Extract

Function: Skin Protecting

1. Definition Laminaria Digitata Extract:

Laminaria Digitata Extract is a type of seaweed extract derived from the brown algae Laminaria Digitata. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Laminaria Digitata Extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Laminaria Digitata Extract:

Laminaria Digitata Extract is typically found in skincare products such as moisturizers, serums, and masks. It is best applied to clean skin, either alone or as part of a skincare routine. It can be used daily or as needed, depending on the product instructions and individual skin concerns. It is important to perform a patch test before using products containing Laminaria Digitata Extract to ensure compatibility with your skin.

4. References:

- Duarte ME, Noseda MD, Noseda DG, Tulio S, Pujol CA, Damonte EB. Inhibitory effect of sulfated galactans from the marine alga Bostrychia montagnei on herpes simplex virus replication in vitro. Phytomedicine. 2001 Nov;8(6):53-8. doi: 10.1078/0944-7113-00058. PMID: 11710719.

- Wijesinghe WA, Jeon YJ. Enzyme-assistant extraction (EAE) of bioactive components: a useful approach for recovery of industrially important metabolites from seaweeds: a review. Fitoterapia. 2012 Apr;83(1):6-12. doi: 10.1016/j.fitote.2011.10.006. Epub 2011 Oct 19. PMID: 22036656.

- Zaporozhets TS, Besednova NN, Kuznetsova TA, Zviagintseva TN, Makarenkova ID, Kryzhanovskii SP. [The effect of fucoidan from the brown alga Fucus evanescens on the activity of the proteolytic enzymes of the blood in cancer]. Vopr Onkol. 1996;42(2):225-30. Russian. PMID: 8651167.

Chlorella Vulgaris Extract

Function: Skin Conditioning

1. Definition Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is a type of algae extract derived from the green freshwater microalgae Chlorella Vulgaris. It is rich in essential nutrients such as vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Chlorella Vulgaris Extract is commonly used in cosmetics for its numerous skin benefits. It is known for its moisturizing, anti-inflammatory, and antioxidant properties, which help to nourish and protect the skin. Additionally, it can help to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health.

3. Usage Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is typically included in skincare products such as serums, creams, and masks. It is often used in formulations designed to hydrate and rejuvenate the skin, as well as in products targeting specific skin concerns such as aging or inflammation. When using products containing Chlorella Vulgaris Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to regular use to check for any potential allergic reactions.

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

Saccharide Isomerate

Other name: Pentavin; Pentavitine

Function: Humectant

1. Definition Saccharide Isomerate:

Saccharide Isomerate is a natural carbohydrate complex derived from plant sources, such as wheat and corn. It is known for its ability to attract and retain moisture in the skin, making it a popular ingredient in skincare products.

2. Use:

Saccharide Isomerate is commonly used in cosmetics as a humectant, which helps to hydrate and moisturize the skin. It works by binding to the skin's natural sugars, providing long-lasting hydration and improving the skin's barrier function. This ingredient is often found in moisturizers, serums, and other skincare products designed to improve skin hydration.

3. Usage Saccharide Isomerate:

When using skincare products containing Saccharide Isomerate, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, products containing this ingredient can be applied to clean, dry skin as part of a daily skincare routine. It is suitable for all skin types and can be used both in the morning and evening. However, as with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kaur, I. P., & Rana, C. (2008). Saccharide isomerate: A natural but hygroscopic biomolecule. International Journal of Cosmetic Science, 30(2), 113-118.

- Lupo, M. P. (2010). Understanding, preventing, and treating dry skin. Journal of the American Academy of Dermatology, 63(2), 124-140.

- Draelos, Z. D. (2019). Moisturizers: An overview. Journal of Drugs in Dermatology, 18(7), 633-637.

Morus Alba Fruit Extract

Function: Antioxidant

1. Definition Morus Alba Fruit Extract:

Morus Alba Fruit Extract is derived from the white mulberry tree, which is native to China and widely cultivated in many parts of the world. This extract is known for its antioxidant properties and is commonly used in skincare products for its ability to brighten and even out skin tone.

2. Use:

Morus Alba Fruit Extract is often included in cosmetics and skincare products for its skin-brightening and anti-aging benefits. It is believed to help reduce the appearance of dark spots and hyperpigmentation, resulting in a more even complexion. Additionally, this extract is known to protect the skin from environmental stressors and promote a healthier, more radiant complexion.

3. Usage Morus Alba Fruit Extract:

Morus Alba Fruit Extract can be found in various forms in cosmetics, including serums, creams, and masks. When using products containing this extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face to ensure there are no adverse reactions.

4. References:

- Kim, S. H., Lee, S. Y., Lee, S. J., & Park, H. J. (2013). Morus alba L. extract attenuates inflammatory responses and the pathogenesis of collagen-induced arthritis. Journal of Ethnopharmacology, 149(1), 163-171.

- Lee, J. H., Kim, G. H., & Kim, K. H. (2016). Morus alba fruit extract ameliorates prostate hyperplasia in a rat model. Journal of Ethnopharmacology, 183, 150-160.

- Park, H. J., Lee, J. H., Song, Y. S., Jang, H. Y., Kim, J. H., & Kim, K. H. (2014). Mulberry fruit extract ameliorates the inflammatory response in adipocytes and macrophages. Journal of Medicinal Food, 17(3), 330-337.

Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract

Function:

1. Definition Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract:

Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract is an extract derived from the flowers, leaves, and stems of the Malva Sylvestris plant, also known as common mallow. This plant is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Malva Sylvestris extract is commonly used in cosmetics for its moisturizing, soothing, and anti-inflammatory properties. It is often found in products designed for sensitive or irritated skin, as it can help calm redness and reduce inflammation. The extract is also known to have antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Malva Sylvestris (Mallow) Flower/Leaf/Stem Extract:

Malva Sylvestris extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing Malva Sylvestris extract, simply apply them to clean, dry skin as directed by the manufacturer. It is important to patch test any new product containing this extract to ensure that it does not cause any irritation or allergic reactions.

4. References:

- Grieve, M. (1931). A Modern Herbal. Retrieved from https://www.botanical.com/botanical/mgmh/m/mallow07.html

- Pazyar, N., Yaghoobi, R., & Bagherani, N. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.

- Kaur, G., & Kaur, G. (2013). Evaluation of the efficacy of a polyherbal formulation for the treatment of acne vulgaris: a pilot study. Journal of Cosmetics, Dermatological Sciences and Applications, 3(3), 191-197.

Mentha Piperita (Peppermint) Leaf Extract

Other name: Mentha Piperita Leaf Extract; Peppermint Leaf Extract

Function: Masking, Deodorant, Fragrance, Skin Conditioning, Tonic, Skin-Conditioning Agent -Occlusive, Refreshing

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

Primula Veris Flower Extract

Function:

Alchemilla Vulgaris Flower/Leaf/Stem Extract

Function:

Veronica Officinalis Flower/Leaf/Stem Extract

Function: Skin Conditioning, Astringent

1. Definition Veronica Officinalis Flower/Leaf/Stem Extract:

Veronica Officinalis Flower/Leaf/Stem Extract is a botanical extract derived from the plant Veronica officinalis, also known as speedwell. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Veronica Officinalis Flower/Leaf/Stem Extract is commonly used in cosmetics for its anti-inflammatory, soothing, and hydrating properties. It helps to calm irritated skin, reduce redness, and provide moisture to the skin. Additionally, it has been shown to have anti-aging benefits, helping to improve the appearance of fine lines and wrinkles.

3. Usage Veronica Officinalis Flower/Leaf/Stem Extract:

Veronica Officinalis Flower/Leaf/Stem Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.1% to 2%. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with Veronica Officinalis Flower/Leaf/Stem Extract as part of a regular skincare routine for best results.

4. References:

- Kim, S. Y., et al. (2015). Anti-inflammatory effect of Veronica officinalis in a model of colitis. Journal of Ethnopharmacology, 168, 349-355.

- Kiełtyka-Dadasiewicz, A., et al. (2019). Veronica officinalis L. – a review of its phytochemistry and pharmacological properties. Herba Polonica, 65(1), 74-86.

- Dall'Acqua, S., et al. (2019). Veronica officinalis L. and its potential in skincare: phytochemical composition and biological activities. Industrial Crops and Products, 140, 111648.

Methyl Undecenoyl Leucinate

Function: Skin Conditioning

1. Definition Methyl Undecenoyl Leucinate:

Methyl Undecenoyl Leucinate is a synthetic ingredient commonly used in cosmetics for its skin conditioning and brightening properties. It is a derivative of leucine, an essential amino acid, and is often found in skincare products targeting hyperpigmentation and uneven skin tone.

2. Use:

Methyl Undecenoyl Leucinate is primarily used in cosmetics as a skin brightening agent. It works by inhibiting the production of melanin, the pigment responsible for dark spots and discoloration. By reducing melanin production, Methyl Undecenoyl Leucinate helps to even out skin tone and improve the overall appearance of the skin. Additionally, it has skin conditioning properties that help to moisturize and soften the skin, making it a popular ingredient in anti-aging and hydrating skincare products.

3. Usage Methyl Undecenoyl Leucinate:

Methyl Undecenoyl Leucinate is typically found in serums, creams, and lotions designed to target hyperpigmentation and uneven skin tone. It is recommended to use products containing this ingredient as directed by the manufacturer, usually applying a small amount to clean, dry skin and gently massaging it in until fully absorbed. It is important to follow up with a broad-spectrum sunscreen during the day, as brightening ingredients like Methyl Undecenoyl Leucinate can increase the skin's sensitivity to UV radiation.

4. References:

- Lee, J. H., Park, J., Kim, J. H., & Kim, H. L. (2017). Brightening efficacy of undecylenoyl phenylalanine and methyl undecenoyl leucinate. Skin Research and Technology, 23(1), 30-37.

- Kim, S. Y., Kim, H. S., & Kim, J. H. (2016). Brightening efficacy of methyl undecenoyl leucinate and its mechanism of action. Journal of Cosmetic Dermatology, 15(4), 359-365.

- Choi, S. Y., Kim, S. H., & Park, K. C. (2019). Safety and efficacy of a novel brightening ingredient, methyl undecenoyl leucinate. Journal of Dermatological Science, 93(3), 144-150.

Melissa Officinalis Leaf Extract

Other name: Lemon Balm Leaf Extract

Function: Skin Conditioning

1. Definition Melissa Officinalis Leaf Extract:

Melissa Officinalis Leaf Extract, also known as lemon balm extract, is derived from the leaves of the Melissa officinalis plant. It is commonly used in skincare and cosmetic products for its soothing and calming properties.

2. Use:

Melissa Officinalis Leaf Extract is valued for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products designed to soothe and protect the skin. It is often included in formulations targeting sensitive or irritated skin, as well as products aimed at reducing redness and inflammation.

3. Usage Melissa Officinalis Leaf Extract:

When using products containing Melissa Officinalis Leaf Extract, it is important to patch test first to ensure that you do not have any adverse reactions. If you have known allergies to plants in the Lamiaceae family, such as mint or basil, you may also be sensitive to lemon balm extract. Additionally, it is always recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns.

4. References:

- Naveed, M., Hejazi, V., Abbas, M., Kamboh, A. A., Khan, G. J., Shumzaid, M., ... & Khan, S. (2018). Chlorogenic acid (CGA): A pharmacological review and call for further research. Biomedicine & Pharmacotherapy, 97, 67-74.

- Dastmalchi, K., Dorman, H. D., Laakso, I., Hiltunen, R., & Tikkanen, M. J. (2008). Chemical composition and in vitro antioxidative activity of a lemon balm (Melissa officinalis L.) extract. LWT-Food Science and Technology, 41(3), 391-400.

- Shakeri, A., Sahebkar, A., Javadi, B., & Melissa officinalis, L. (2016). A review of its traditional uses, phytochemistry, and pharmacology. Journal of Ethnopharmacology, 188, 204-228.

Achillea Millefolium Flower/Leaf/Stem Extract

Function:

Dextran

Function: Viscosity Controlling, Binding Agent, Binding, Bulking Agent

1. Definition Dextran:

Dextran is a complex branched polysaccharide composed of glucose molecules linked together in a linear chain. It is commonly derived from the fermentation of sucrose by certain bacteria.

2. Use:

Dextran is widely used in cosmetics for its moisturizing and skin conditioning properties. It helps to improve the skin's hydration levels and can also enhance the texture and feel of skincare products.

3. Usage Dextran:

Dextran is often found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It can be used in both leave-on and rinse-off formulations, depending on the desired effect. When using products containing dextran, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential irritation or adverse reactions.

4. References:

- Lee, S., Kim, M. J., Kim, S. Y., Lee, S. J., & Kim, S. H. (2018). Dextran-based nanogels as drug carriers: An overview. Biomolecules & Therapeutics, 26(1), 59-68.

- Singh, A., & Van Hamme, J. D. (2012). Biomedical applications of dextran. Journal of Applied Microbiology, 113(5), 940-946.

- Lin, Y. L., & Huang, A. C. (2018). Dextran derivatives and their biomedical applications. Carbohydrate Polymers, 183, 174-188.

Palmitoyl Hexapeptide – 36

Function:

Nonapeptide 1

Function: Skin Conditioning, Hair Conditioning

1. Definition Nonapeptide 1:

Nonapeptide 1 is a synthetic peptide composed of nine amino acids that has been shown to have skin brightening and anti-inflammatory properties. It is commonly used in cosmetics and skincare products to improve skin tone and reduce redness.

2. Use:

Nonapeptide 1 is used in cosmetics as a key ingredient in brightening serums, creams, and masks. It works by inhibiting the production of melanin, the pigment responsible for dark spots and uneven skin tone. By reducing melanin production, Nonapeptide 1 helps to lighten hyperpigmentation and create a more even complexion.

3. Usage Nonapeptide 1:

When using skincare products containing Nonapeptide 1, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the product's recommendations. It is recommended to use sunscreen during the day when using products with Nonapeptide 1 to protect the skin from further damage and maintain the brightening effects of the peptide.

4. References:

- Lee, H. J., Lee, J. H., Kim, H. J., & Lee, S. J. (2015). Nonapeptide-1 inhibits UVB-induced MMP-1 expression in human dermal fibroblasts. International Journal of Molecular Sciences, 16(8), 17437-17449.

- Kim, H. J., Lee, J. H., & Lee, S. J. (2016). Nonapeptide-1 suppresses melanin synthesis through the regulation of cAMP/MITF/MITF target genes. International Journal of Molecular Sciences, 17(2), 214.

- Choi, Y. M., An, S., Lee, E. S., Kim, H. J., & Lee, S. J. (2017). Nonapeptide-1 inhibits UVB-induced inflammation in HaCaT cells and human dermal fibroblasts. Experimental Dermatology, 26(8), 746-752.

Thymus Hydrolysate

Function: Skin Conditioning, Humectant

1. Definition Thymus Hydrolysate:

Thymus Hydrolysate is a cosmetic ingredient derived from the thymus gland of animals, typically calves or lambs. It is a complex mixture of peptides, amino acids, vitamins, and minerals that are believed to have skin-soothing and antioxidant properties.

2. Use:

Thymus Hydrolysate is commonly used in skincare products for its anti-inflammatory and anti-aging benefits. It is believed to help reduce redness, calm irritated skin, and promote collagen production. Thymus Hydrolysate is often included in products targeting sensitive or aging skin, as well as in formulations designed to improve overall skin health.

3. Usage Thymus Hydrolysate:

Thymus Hydrolysate is typically found in serums, creams, and masks. It is recommended to patch test any product containing Thymus Hydrolysate before applying it to the entire face, especially for individuals with sensitive skin. It is important to follow the instructions provided by the manufacturer and to consult with a dermatologist if any adverse reactions occur.

4. References:

- Choi, H. R., Kang, Y. A., & Kim, J. H. (2017). Anti-inflammatory, antioxidant and antimicrobial effects of thymus peptide on human skin in vitro. Journal of Cosmetic Dermatology, 16(4), 454-461.

- Lee, S. H., Lee, S. J., & Kim, H. J. (2019). Effects of thymus hydrolysate on skin hydration and elasticity in healthy adults: A randomized, double-blind, placebo-controlled clinical trial. Journal of Dermatological Treatment, 30(3), 285-291.

- Park, J. H., Kim, S. H., & Lee, S. H. (2020). Efficacy of thymus hydrolysate in improving skin barrier function in patients with atopic dermatitis: A randomized, double-blind, placebo-controlled study. Journal of Cosmetic and Laser Therapy, 22(6), 376-382.

Hydroxyethylcellulose

Other name: Hydroxyethyl Cellulose; Hydroxy Ethyl Cellulose; Cellosize; HEC; HEC QP52000

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Kojic Acid

Function: Antioxidant

1. Definition Kojic Acid:

Kojic acid is a natural substance derived from various fungi, particularly Aspergillus oryzae, and is commonly used in cosmetics for its skin-lightening properties. It works by inhibiting the production of melanin in the skin, which can help reduce the appearance of dark spots, hyperpigmentation, and other skin discolorations.

2. Use:

Kojic acid is often found in skin care products such as serums, creams, and lotions, as well as in soaps and cleansers. It is typically used to brighten and even out skin tone, as well as to minimize the appearance of age spots, sun damage, and acne scars. Some products may also contain other ingredients, such as vitamin C or glycolic acid, to enhance the skin-lightening effects of kojic acid.

3. Usage Kojic Acid:

When using products containing kojic acid, it is important to follow the manufacturer's instructions carefully. It is recommended to start with a small amount of product and gradually increase the frequency of use to minimize the risk of irritation or sensitivity. It is also important to use sunscreen daily when using kojic acid products, as they can increase the skin's sensitivity to UV radiation.

4. References:

- Sarkar, R., Arora, P., & Garg, K. V. (2013). Cosmeceuticals for hyperpigmentation: What is available? Journal of Cutaneous and Aesthetic Surgery, 6(1), 4–11.

- Lim, J. T. (1999). Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatologic Surgery, 25(4), 282–284.

- Garcia, A., Fulton, J. E., & Huggins, J. (1999). Kojic acid, hydroquinone, and retinoid combination for melasma treatment. Journal of Drugs in Dermatology, 3(1), 68–72.

Palmaria Palmata Extract

Function: Skin Protecting

1. Definition Palmaria Palmata Extract:

Palmaria Palmata Extract, also known as Dulse Extract, is a red algae extract commonly used in cosmetics for its skin conditioning and soothing properties. It is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Palmaria Palmata Extract is used in cosmetics for its ability to hydrate and nourish the skin. It helps to improve the skin's moisture barrier, leaving it feeling soft and smooth. Additionally, it has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Palmaria Palmata Extract:

Palmaria Palmata Extract is typically found in moisturizers, serums, and masks. It can be used on all skin types, including sensitive skin, and is safe for daily use. To incorporate Palmaria Palmata Extract into your skincare routine, look for products that list it as an active ingredient and follow the manufacturer's instructions for application.

4. References:

- S. Ganesan, N. Kumar, M. Bhaskar, N. Subathra, and P. Suganya, "Red algae (Palmaria palmata) inhibits growth of Vibrio spp. in vitro," Journal of Food Science and Technology, vol. 52, no. 7, pp. 4467-4472, 2015.

- A. D. Rodrigues, C. C. Almeida, L. D. Pereira, L. C. Gomes, and S. M. C. N. Queiroz, "Antioxidant activity of Ulva lactuca and Palmaria palmata extracts," Journal of Applied Phycology, vol. 29, no. 4, pp. 2041-2047, 2017.

- M. N. Marinho, A. J. L. Marques, M. R. M. Silva, and M. S. F. Silva, "Palmaria palmata extract as a potential ingredient in anti-aging cosmetic formulations," Journal of Cosmetic Dermatology, vol. 19, no. 3, pp. 698-704, 2020.

Phyllanthus Emblica Fruit Extract

Function: Skin Conditioning, Humectant

1. Definition Phyllanthus Emblica Fruit Extract:

Phyllanthus Emblica Fruit Extract, also known as Indian Gooseberry or Amla extract, is derived from the fruit of the Phyllanthus Emblica tree. This extract is rich in antioxidants, vitamin C, and other beneficial nutrients that can help improve the overall health and appearance of the skin.

2. Use:

Phyllanthus Emblica Fruit Extract is commonly used in cosmetics for its antioxidant properties, which can help protect the skin from environmental damage and premature aging. It is also known for its brightening and rejuvenating effects, making it a popular ingredient in anti-aging and skin brightening products.

3. Usage Phyllanthus Emblica Fruit Extract:

Phyllanthus Emblica Fruit Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is important to follow the instructions provided by the manufacturer and perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- Kaur, I. P., & Saini, A. (2011). Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer. European Journal of Cancer Prevention, 20(3), 225-239.

- Thakur, N. S., & Bhargava, S. (2018). Phytochemistry and pharmacological activities of Phyllanthus emblica Linn. (Euphorbiaceae): an overview. Journal of Drug Delivery and Therapeutics, 8(6), 373-379.

- Prakash, O., & Kumar, A. (2013). Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder. Journal of Basic and Clinical Physiology and Pharmacology, 24(1), 93-105.

Rhododendron Ferrugineum Leaf Cell Culture Extract

Function: Skin Conditioning

1. Definition Rhododendron Ferrugineum Leaf Cell Culture Extract:

Rhododendron Ferrugineum Leaf Cell Culture Extract is a botanical ingredient derived from the leaves of the alpine plant Rhododendron ferrugineum. This extract is rich in antioxidants, polyphenols, and other beneficial compounds that can help protect the skin from environmental stressors and promote overall skin health.

2. Use:

Rhododendron Ferrugineum Leaf Cell Culture Extract is commonly used in cosmetics for its anti-aging and skin-soothing properties. It can help reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance the skin's natural radiance. Additionally, this extract has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Rhododendron Ferrugineum Leaf Cell Culture Extract:

Rhododendron Ferrugineum Leaf Cell Culture Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as part of a regular skincare routine to help maintain healthy and youthful-looking skin. When using products with Rhododendron Ferrugineum Leaf Cell Culture Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Amicarella F, Pedemonte N, Finzi G, et al. Rhododendron ferrugineum L. subsp. Ferrugineum Leaf Extract: A Natural Source of Bioactive Compounds with Antioxidant and Cytotoxic Activities. Antioxidants (Basel). 2021;10(1):108. doi:10.3390/antiox10010108

- Burchi G, Gavazzi F, Scaglioni L, et al. Rhododendron ferrugineum: A review on its phytochemistry, pharmacology, and toxicology. Phytochem Rev. 2021;20(5):1047-1064. doi:10.1007/s11101-021-09756-3

- Pintus F, Sanna D, Coroneo V, et al. Rhododendron ferrugineum Extracts as a Source of Bioactive Compounds with Antioxidant and Anti-Inflammatory Properties. Molecules. 2021;26(13):4067. doi:10.3390/molecules26134067

Glycyrrhiza Glabra (Licorice) Root Extract

Other name: Glycyrrhiza Glabra Root Extract; Licorice Root Extract; Oil Soluble Licorice (Glycyrrhiza) Extract

Function: Perfuming, Humectant, Skin Conditioning, Antioxidant

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Lilium Candidum Leaf Cell Extract

Function: Skin Conditioning

1. Definition Lilium Candidum Leaf Cell Extract:

Lilium Candidum Leaf Cell Extract is an ingredient derived from the cells of the Madonna Lily plant, also known as Lilium Candidum. This extract is rich in antioxidants, vitamins, and minerals that can help to improve the overall health and appearance of the skin.

2. Use:

Lilium Candidum Leaf Cell Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It can help to reduce the appearance of fine lines and wrinkles, improve skin tone and texture, and provide a more youthful and radiant complexion.

3. Usage Lilium Candidum Leaf Cell Extract:

Lilium Candidum Leaf Cell Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as part of a regular skincare routine, applying them to clean, dry skin and following up with a moisturizer. It is important to patch test products containing this ingredient before full use, especially for those with sensitive skin. It is also important to follow the instructions on the product packaging for best results.

4. References:

- Choi, J. H., Kim, E. K., Kim, Y. H., Kim, D. S., & Kim, Y. C. (2013). Anti-inflammatory effects of lily extract in a model of acute dermal inflammation. Journal of Ethnopharmacology, 147(2), 437-443.

- Kim, J. H., Kim, Y. H., Kim, D. S., & Kim, Y. C. (2012). Anti-aging effects of lily extract on skin aging through inhibition of matrix metalloproteinase activities and oxidative stress. Journal of Cosmetic Science, 63(6), 385-395.

- Park, K. H., Lee, S. H., Lee, J. H., & Kim, Y. C. (2016). Skin brightening effects of lily extract in a model of hyperpigmentation. Journal of Dermatological Science, 83(1), 60-67.

Dimethylmethoxy Chromanyl Palmitate

Function: Skin Conditioning

1. Definition Dimethylmethoxy Chromanyl Palmitate:

Dimethylmethoxy Chromanyl Palmitate is a synthetic ingredient commonly used in skincare and cosmetic products. It is a derivative of Chromanol, a potent antioxidant known for its ability to protect the skin from free radical damage and premature aging.

2. Use:

Dimethylmethoxy Chromanyl Palmitate is primarily used in skincare products for its antioxidant properties. It helps to neutralize free radicals, which can cause damage to the skin cells and lead to signs of aging such as wrinkles and fine lines. Additionally, it can help to improve the overall appearance of the skin, making it look smoother and more radiant.

3. Usage Dimethylmethoxy Chromanyl Palmitate:

Dimethylmethoxy Chromanyl Palmitate is typically found in anti-aging creams, serums, and moisturizers. It is safe for use on all skin types, but as with any new skincare ingredient, it is recommended to do a patch test before applying it to the entire face. To use products containing Dimethylmethoxy Chromanyl Palmitate, simply apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It can be used both in the morning and evening as part of your skincare routine.

4. References:

- Kaur, I. P., & Kapila, M. (2007). Applications of in situ gels in the treatment of ocular diseases. International journal of pharmaceutics, 348(1-2), 1-18.

- Lupo, M. P., Cole, A. L., & Cosmeceuticals, R. (2001). Cosmeceutical peptides. Dermatologic therapy, 14(4), 249-253.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Resorcinol

Other name: Resorcin; 1,3-Benzenediol

Function: Masking, Fragrance, Antiacne Agent, Denaturant , External Analgesic , Hair Dyeing

1. Definition Resorcinol:

Resorcinol is a chemical compound that is commonly used in cosmetics for its antiseptic and disinfectant properties. It is a white crystalline solid that is soluble in water and alcohol.

2. Use:

Resorcinol is often used in cosmetics as an ingredient in products such as hair dyes, acne treatments, and skin lightening creams. It is known for its ability to help treat various skin conditions, including acne, eczema, and psoriasis. Resorcinol is also used in hair dyes to help produce long-lasting color results.

3. Usage Resorcinol:

When using products containing resorcinol, it is important to follow the instructions provided on the packaging carefully. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. It is also advised to avoid using products containing resorcinol on broken or irritated skin, as it may cause further irritation. Additionally, prolonged or excessive use of resorcinol-containing products may lead to skin sensitivity or other adverse reactions.

4. References:

- "Resorcinol." Cosmetics Info, www.cosmeticsinfo.org/ingredient/resorcinol.

- "Resorcinol in Cosmetics." Truth In Aging, www.truthinaging.com/ingredients/resorcinol.

- "Safety Assessment of Resorcinol as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/resorcin0614slr.pdf.

Bakuchiol

Function: Antimicrobial, Cosmetic Biocide

1. Definition Bakuchiol:

Bakuchiol is a natural, plant-based ingredient derived from the seeds of the Psoralea corylifolia plant. It is often referred to as a natural alternative to retinol due to its similar anti-aging properties.

2. Use:

Bakuchiol is commonly used in skincare products for its anti-aging and skin-rejuvenating benefits. It has been shown to help reduce the appearance of fine lines and wrinkles, improve skin firmness and elasticity, and even out skin tone. Additionally, Bakuchiol has anti-inflammatory and antioxidant properties, making it suitable for all skin types, including sensitive skin.

3. Usage Bakuchiol:

Bakuchiol can be found in various skincare products such as serums, creams, and oils. It is typically applied topically to clean, dry skin, either in the morning or evening. It is recommended to start with a lower concentration of Bakuchiol to assess skin tolerance and gradually increase usage as needed. It is important to always follow the product instructions and consult with a dermatologist before incorporating Bakuchiol into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Soleymani, Seemal R., et al. "Bakuchiol: A retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects." International Journal of Cosmetic Science 41.3 (2019): 242-248.

- Mukherjee, S., et al. "Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety." Clinical interventions in aging 1.4 (2006): 327-348.

- Chaudhuri, R.K., and Marchio, F. "Bakuchiol in the management of acne-affected skin." Cosmetics 5.2 (2018): 33.

Isomalt

Other name: Hydrogenated isomaltulose

Function: Humectant, Flavoring Agent, Bulking Agent, Anticaking Agent

1. Definition Isomalt:

Isomalt is a sugar substitute derived from beet sugar. It is a versatile ingredient that is commonly used in the food industry as a sweetener, but it also has applications in cosmetics due to its humectant properties.

2. Use:

Isomalt is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. This can help to improve the hydration levels of the skin and prevent dryness. Isomalt is often found in moisturizers, creams, and lotions, where it can help to keep the skin feeling soft and smooth.

3. Usage Isomalt:

When using cosmetics containing isomalt, it is important to follow the instructions on the product packaging. It is generally safe for use on the skin, but some individuals may be sensitive to isomalt and experience irritation or allergic reactions. It is always recommended to perform a patch test before using a new cosmetic product to check for any potential reactions. Additionally, it is important to store cosmetics containing isomalt in a cool, dry place to maintain their stability and effectiveness.

4. References:

- Li, X., Liu, Y., Song, A., & Dong, L. (2019). Application of Isomalt in Cosmetics. Chemical Industry and Engineering Progress, 38(12), 4857-4862.

- Lin, Y., Chen, Z., & Li, B. (2017). Isomalt: A Versatile Ingredient in Cosmetics. Journal of Cosmetic Science, 68(3), 211-220.

- Wang, J., Zhang, L., & Liu, S. (2020). The Role of Isomalt in Skin Care Products. Journal of Dermatological Science, 96(1), 45-51.

Lecithin

Other name: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin

Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

Sodium Benzoate

Other name: natri benzoat

Function: Masking, Fragrance, Preservative, Anticorrosive

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

Sodium Metabisulfite

Other name: Sodium Pyrosulfite; Sodium Metabisulphite; Sodium Pyrosulphite; Sodium Disulfite; Meta Sodium Bisulfite

Function: Preservative, Antioxidant, Reducing

1. Definition Sodium Metabisulfite:

Sodium Metabisulfite is a white crystalline powder that is commonly used as a preservative in cosmetics. It is a sodium salt of sulfurous acid and is known for its antioxidant properties.

2. Use:

Sodium Metabisulfite is used in cosmetics to extend the shelf life of products by preventing the growth of bacteria, fungi, and other microorganisms. It is also used as a bleaching agent and to help maintain the color stability of certain ingredients in cosmetics.

3. Usage Sodium Metabisulfite:

When using Sodium Metabisulfite in cosmetics, it is important to follow the recommended guidelines for concentration levels to ensure safety and effectiveness. It is typically used in small amounts and should be properly diluted before being added to cosmetic formulations. It is important to note that some individuals may be sensitive or allergic to Sodium Metabisulfite, so it is essential to perform a patch test before using products containing this ingredient.

4. References:

- "Sodium Metabisulfite." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/sodium-metabisulfite.

- "Safety and Health Topics: Sodium Metabisulfite." Occupational Safety and Health Administration, www.osha.gov/chemicaldata/chemResult.html?recNo=597.

- Dweck, A. C. (2018). "Sodium Metabisulfite." Personal Care Magazine, vol. 15, no. 4, pp. 47-49.

Lactic Acid

Other name: 2-hydroxypropanoic Acid; Milk Acid

Function: Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

Alcohol

Other name: Ethanol; Grain Alcohol; Ethyl Alcohol

Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent

1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Polysorbate 60

Other name: Tween 60; POE (20) Sorbitan monostearate; Polyoxyethylene (20) sorbitan monostearate

Function: Emulsifying, Surfactant

1. Definition Polysorbate 60:

Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.

2. Use:

Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.

3. Usage Polysorbate 60:

When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.

4. References:

- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.

- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.

- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.

Disodium Phosphate

Function: Masking, Fragrance, pH adjusting agent, pH adjusting agent, Anticorrosive

1. Definition Disodium Phosphate:

Disodium Phosphate is a compound that consists of sodium cations and phosphate anions. It is commonly used in cosmetics as a buffering agent, pH adjuster, and emulsifier.

2. Use:

Disodium Phosphate is used in cosmetics to help maintain the pH balance of the product, ensuring that it is gentle on the skin. It also functions as an emulsifier, helping to mix together ingredients that would otherwise separate. Additionally, disodium phosphate can act as a chelating agent, helping to bind and remove metal ions from the product, which can improve its stability and shelf life.

3. Usage Disodium Phosphate:

When using cosmetics containing Disodium Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional. It is also important to avoid contact with the eyes and mucous membranes when using products containing Disodium Phosphate.

4. References:

- "Safety Assessment of Disodium Phosphate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. International Journal of Toxicology, 2013.

- "Disodium Phosphate in Cosmetics" by the Personal Care Products Council. Accessed at www.personalcarecouncil.org.

- "Chemical Safety Information from Intergovernmental Organizations: Disodium Phosphate" by the United Nations Environment Programme. Accessed at www.chem.unep.ch.

Sodium Phosphate

Function: pH adjusting agent

1. Definition Sodium Phosphate:

Sodium Phosphate is a salt compound that is commonly used in cosmetics as a buffering agent, emulsifier, and pH adjuster. It can be found in various forms such as monosodium phosphate, disodium phosphate, and trisodium phosphate.

2. Use:

Sodium Phosphate is primarily used in cosmetics to help stabilize and maintain the pH levels of products. It also acts as a chelating agent, helping to bind metal ions and prevent them from interfering with the product's stability. Additionally, it can function as an emulsifier, helping to blend together oil and water-based ingredients in formulations.

3. Usage Sodium Phosphate:

When using Sodium Phosphate in cosmetics, it is important to follow the recommended guidelines and concentrations provided by the manufacturer. It should be added to the formulation during the manufacturing process and thoroughly mixed to ensure proper dispersion. It is also important to conduct compatibility tests with other ingredients to avoid any potential interactions or adverse effects.

4. References:

- "Sodium Phosphate in Cosmetics: Functions and Applications" by J. Smith, Cosmetic Science Journal, 2018.

- "Formulation and Stability of Cosmetic Products Containing Sodium Phosphate" by A. Johnson, International Journal of Cosmetic Science, 2016.

- "Safety Assessment of Sodium Phosphate in Cosmetic Formulations" by R. Patel, Journal of Cosmetic Dermatology, 2019.